Physical Sciences and Mathematics Commons^™

Thermodynamics Of Charge Transfer Complexes, Reed J. Jensen

Theses and Dissertations

Charge transfer complexes were studied spectrophotometrically in the liquid state by a modified Benesi-Hildabrand method. TiCl_4 - Benzene and TiCl_4 - diphenyl ether solutions were found to form contact charge transfer complexes, that is complexes with very weak and non-directional interactions. The systems TiCl_4 - anisole and TiCl_4 - diethyl ether form complexes of the types AD and AD_2 where A stands for TiCl_4 and D stand s for the organic donor. The formation constants for the complexes were, for the TiCl_4 - anisole, K_1 = 0.077, K_2 = 0.01; and TiCl_4 - diethyl ether, K_1= 3.0, K_2 = 1.0. …

The Kinetics And Mechanism Of The Reaction Of Molybdenum(V) With Iodine, Oxygen And Nitrate, Ervin Park Guymon

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Molybdenum compounds present a series of baffling chemical puzzles. By no means are all of these yet even clearly defined and many may never be. This complexity results from the ability of molybdenum to form six different oxidation states, which can possess three different coordination numbers. Furthermore, molybdenum compounds readily disproportionate to yield mixed valence compounds; and finally, molybdate ions readily aggregate in solution to form a variety of polyions by polymerization-condensation reactions which are controlled by pH and the concentration of the system. Molybdenum's complexity can best be summed up in the words of the late Edgar Smith who …

Thermochemistry Of Cyclophanes, Chyi-Feng Shieh

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The syntheses and properties of various cyclophanes have been extensively investigated by Cram and others. The paracyclophanes are compounds in which benzene rings are linked to each other by two saturated chains at the para positions, as in structure I. When they are joined to the meta positions, they are called metacyclophanes.

Properties Of Chlorophyll Derivatives Bonded To Polymers, Richard Grant Jensen

Theses and Dissertations

Two types of water-soluble complexes of chlorophyll a with organic polymers have been investigated: chlorophyll a coordinately bonded to poly 4-vinylpyridine and a chlorophyll derivative, Mg-chlorin e_6 phytyl methyl ester, covalently bonded to GANTREZ AN (poly (methyl vinyl ether/maleic anhydride) ). The first complex was observed upon dissolving chlorophyll a and poly 4-vinylpyridine in aqueous ethanol solutions. The Mg-chlorin e_6 diester-GANTREZ AN complex (chlorophyll a/polymer) was made by aminolysing the chlorophyll ring V with 1, 6-hexanediamine to give an intermediate product, Mg-chlorin e_6 -6-N-(6' -aminohexyl) carboxamide, phytyl methyl ester. This was attached to GANTREZ AN by linkage of the 6'-amine …

The Synthesis And Reactions Of 8-Carboxy Isatoic Anhydride, James E. Scheirer

Chemistry Honors Papers

This 34 page thesis examines the preparation and characterization of 8-carboxy isatoic anhydride and the study of its reactions, leading to the synthesis of compounds of new composition.

A Thermodynamic Study Of (1) Ligand Replacement Reactions And (2) The Interaction Of Hgcl[Subscript 2](Aq) With Hydroxide Ion, Ethylenediamine, Glycinate Ion, And Methylamine, Jerry Alvin Partridge

Theses and Dissertations

A method is reported for determining the species formed in solution by ligand replacement reactions. Reactions in dilute aqueous solution were studied in which the Cl^- on HgCl_2(aq) was replaced by hydroxide ion, ethylenediamine, glycinate ion, and methylamine. The species formed by the replacement reactions were established through computer analysis of pH titration data. Various reaction sequences were proposed for each system and log K values were calculated for each sequence. The selection of the correct reaction sequence for each system was based on the premise that only when the correct sequence is proposed will consistent log K values be …

Hydrogenation Of 4-Methylcinnoline, William E. Maycock

Theses and Dissertations

The rapid expansion of knowledge of cinnoline chemistry since 1941 has not included the hydrocinnolines. Not one catalytic hydrogenation of a fully aromatic cinnoline had been reported. This thesis is an effort to enlarge knowledge of this particular area of cinnoline chemistry. The work is a natural outgrowth of that done at Brigham Young University on decahydroquinoxaline, both the cis- and trans- isomers having been prepared and characterized. 4-Methylcinnoline, prepared by the method of Jacobs, et.al., was hydrogenated in neutral and acidic ethanolic solutions at 2000-3000 psig. hydrogen pressure and 100-266°. The catalysts used were 5% palladium on alumina, ruthenium …

A Study Of The Boron - Curcumin System, John Bowlin Forehand

Master's Theses

The discovery of the usefulness of curcumin for detecting boron was made over 100 years ago. Since that time a great deal of work has been done in developing new methods based on this compound and in modifying and improving existing methods. However, very little has been done to determine the mechanism of the reactions involved or the structures of the compounds formed.

The purpose of this work was to gather evidence in support of the mechanism proposed in 1956 by Powell, Hardcastle and Poindexter for the formation of the boron - oxalic acid - curcumin complex (Rubrocuraumin) in the …

Coordination Compounds And Complex Ions, Carole Nelson

Honors Theses

Coordination compounds and complex ions are an important and practical part of fundamental chemistry. Their composition and formation should be understood by a chemistry student.

Transformations Of Tryptamine And Tryptophan By Basidiomycetes, Hsaio-Lung Cheng

Masters Theses

"The product formed from tryptamine by Trichloloma nudum was identified as indoleacetic acid (IAA) and from tryptophan by Cantharellus cibrarius as indolelactic acid (ILA). The products were extracted from the spent media with organic solvents. Purification and identification of the crystalline transformation products were accomplished by means of paper chromatography, spectrophotometry and thin layer chromatography.

The conversion of tryptamine and tryptophan was also studied in cultures of Lencopaxillus paradoxus, Pluteus granularis and Pleuatus ostreatus. Only Pluteus granularis was found to transform tryptamine into IAA. Lencopaxillus paradoxus transformed tryptamine into oxindoleacetic acid (OIAA).

Paper chromatography proved to be useful …

Studies On The Conversion Of Indole Acetic Acid And Oxindole Acetic Acid By Hygrophorous Conicus, Barbara Ruth Patterson

Masters Theses

"The fungus, Hygrophorous conicus, produces the enzyme, indole acetic acid oxidase, when grown in the presence of indole acetic acid (IAA) or tryptamine. The IAA acts both as an inducer and a substrate for this intracellular enzyme. The product of the oxidation catalyzed by the IAA oxidase is oxindole acetic acid (OIAA). Since the IAA and OIAA absorb maximally at two different wavelengths the use of spectrophotometric analysis was possible for assaying for the IAA oxidase activity. Paper chromatography was used for qualitative identification of the IAA and OIAA. The rate of growth and the rate of formation of the …

Stereochemistry Of Chlorinated Diels-Alder Adducts, Harry R. Musser

Masters Theses

"Hexachlorocyclopentadiene and related compounds have been studied extensively in connection with Diels-Alder reactions. Many of the adducts formed are used as intermediates in insecticide syntheses. It is of interest to study the stereochemistry of the adducts of one of the hexachlorocyclopentadiene derivaites. 5,5-Dimethoxy-1,2,3,4-tetrachlorocyclopentadiene and various dienophiles, when allowed to react, yield compounds of the bridges bicyclo [2.2.1] hept-2-ene series. The study of the endo and/or exo configuration of various functional groups such as carboxyl, aldehyde, and hydroxymethyl can be related to the known exo-5-hydroxymethyl1-1,2,3,4-tetrachlorobicyclo-[2.2.1] help-2-ene-7-one"--Introduction, page [1].

Construction Of Nuclear Magnetic Resonance Spectroscope And Its Calibration, Irshad Ahmad

University of the Pacific Theses and Dissertations

Soon after the importance of Nuclear Magnetic Resonance Spectroscopy was established more sophisticated instruments started coming into use. At present High Resolution Spectroscopes which are of the self-recording type are extensively used in research.

However, the high cost of the instrument prevents its use in smaller and poorer schools. In recent years a low cost instrument of the single coil type has been constructed by the Aero Medical Laboratory which is alright for demonstration purposes but cannot be used for research because of low resolution.

The idea of the present project was to see whether a similar instrument of double …

Spectrophotometric Study Of The Copper (Ii) Complexes Of Alpha-Omega Diamino Adipic Acid And Alpha-Omega Diamino Pimelic Acid, Julius Caesar Hastings

University of the Pacific Theses and Dissertations

The chenistry of diamino dicarboxylic acids together with that of monoamino dicarboxylie and monocarboxylic acids in of great importance to the chemist because of the rolation- ship of these compounds to the biochemistry of cancer.

Diamino dicarboxylic acids in general, contain two asymmetric carbon atoms and may exist in one optically inactive and two optically active forma. Alpha-omoga diamino pinolic acid is the only member of the alpha-omoga diamino dicarboxylic acids thus far known to occur naturally.

Polarography Of Selected Metal Ions In Anhydrous Aliphatic Diamines, Frederick William Foss Jr.

University of the Pacific Theses and Dissertations

A search of the literature revealed that no study has sought to measure and compare the polarographic solvent properties of the anhydrous aliphatic diamines. In fact, there has been no reported instance of the use of anhydrous 1,3-propanediamine or 1,4-butanediamine in any electro- chemical system.

Some Spectrophotometric Studies Of Molecular Complexes For Phenanthrene, Anthracene, Pyrene, Chrysene, And Benzanthracene With Iodine Monochloride, Joe Boyd Coacher

University of the Pacific Theses and Dissertations

The principal purpose of the present study was to prove the existence of the weak interaction between the halogenoid iodine monochloride and the condensed polycyclic aromatic hydrocarbons, phenanthrene, anthracene pyrene, chrysene, and benzanthracene (see Figure 1).

Use Of Neutron Activation Analysis In The Study Of Biological Disposition Of Antimony Compounds, Moustafa Mahmoud Mansour

Archived Theses and Dissertations

No abstract provided.

Fluorescein As A Reagent In A Spectrophotometric Determination Of Micro-Amounts Of Iodine: Application To Glucose Determination, Donald Eugene Braun

University of the Pacific Theses and Dissertations

The increasing awareness of the close inter-relationships between biological activity and chemical reactions has resulted in a rapidly growing pursuit of biochemical knowledge. Research in the related fields of medicine, virology, pharmacy, and biophysics is expanding at a rapid rate. Problems related to food production for an exploding population, space explorations, world health issues, the utilization of the resources of the oceans, and the proper employment of energy sources have spurred man to delve deeper into the secrets of creation. The mysteries of life itself are slowly being revealed through finding in egentic studies.

With this ever expanding biochemical and …

Polarography Of Mercury In Aliphatic Diamines, John Charles Richardson

University of the Pacific Theses and Dissertations

The problem taken for investigation was discovered when a cryostat needed for use in polarography in liquid ammonia (the original problem) was found broken. For experience it was decided to turn to another form of nonaqueous polarography while the parts were on order. Materials remaining from a previous diamine investigation by Foss (21) were found in the laboratory. After reading the dissertation in which they had been used, it was decided to reproduce some of the results that had been previously obtained. Following preparation of the chemicals and several polarographic runs, a previously unreported wave was persistently observed. Further perusal …

The Synthesis Of 2,6-Diamino-2,6-Dideoxy-D-Galactose., Lester Vern Smith Jr.

University of the Pacific Theses and Dissertations

The objectives of this research problem were divided into several parts. The first objective was to develop a practical method of preparing 2,6-diamino-2,6-dideoxy-galactose. A second objective was to investigate the derivatives of benzyl-N-carbobenzoxy-α-D-galactosaminide. FInally, the third objective was to lay the groundwork for another possible route for the synthesis of 2,6-diamino-2,6-dideoxy-galactose other than the uronic acid route.

The Binary Halides Of Molybdenum(Iv) And Tungsten(Iv) And The Oxochlorides Of Tungsten(Vi), Edward Roy Epperson

University of the Pacific Theses and Dissertations

It was the purpose of this study to investigate the reaction of molybdenum and tungsten dioxides with carbon tetrachloride and bromoform (via the method of Knox and Tyree) to produce anhydrous molybdenum and tungsten tetrachlorides and bromides and to determine whether the method is a reliable one for the synthesis of these compounds. Out of this grew an investigation into the preparation of the oxochlorides of tungsten(VI) using the same preparative technique.

The results of this study are here set forth. An attempt is made to systematize the published material on the synthesis and properties of the binary halides of …

Polarography As A Measure Of Ionic Environment, James Wilburne Larsen

University of the Pacific Theses and Dissertations

The present work is a polarographic study of the alkali metals and selected first row transition metals in DMSO (dimethylsulfoxide) with tetraethylammonium perchlorate as a supporting electrolyte. DMSO was chosen as a solvent because of its interesting solvent and complexing properties. Tetraethylammonium perchlorate was chosen as a supporting electrolyte because of its lack of complex forming tendencies and because of the wide range of voltages available for polarographic investigation before the supporting electrolyte ions react electrochemically.

One of the problems, particularly in nonaqueous polarography, is the low conductivity of the solutions leading to high cell resistance. As current flows through …

Anomers Of D-Galactosamine Benzoates, Robert Stanley Strong

University of the Pacific Theses and Dissertations

D-Galactosamine has been known as one of the rarer amino sugars, occurring widely distributed in small concentrations in living organisms. The biological importance of D-galactosamine and its derivatives was thought to justify a study of the chemical properties of this group of compounds. As a result of this study the reactions of D-galactosamine have been found to differ more than previously thought from those of D-glucosamine, the more common amino sugar

For this investigation D-galactosamine hydrochloride was isolated from chondroitin sulfate, a polysaccharide obtained from the cartilaginous tissues of animals. This was changed by appropriate reactions to the 1,3,4,6-tetra-0-benzoyl-N-carbobenzoxy-α-β-D-galactosamine (III). …

Thin Layer Chromatography Of The Platinum Metal Ions, Anthony Paul Trujillo

University of the Pacific Theses and Dissertations

Recent work in this laboratory has centered about the platinum metals and their complexes. The current activity in thin layer chromatography, and especially the work of Seiler in using the technique for inorganic applications, led to speculation regarding the separation and identification of the platinum metal ions by thin layer chromatography. Specifically, then, the purpose of this study was twofold: (1) to find a suitable adsorbent and solvent system to separate some or all of the platinum metal ions; (2) to find appropriate locating agents, so that once the separation had been accomplished, the ions could be identified.

Derivatives Of Benzyl N-Benzoyl-A-D-Glucosaminide, Kenji Miyai

University of the Pacific Theses and Dissertations

Within the past few decades, interest in the field of aminosugar chemistry has been stimulated to a remarkable degree and the discovery and syntheses of a wide range of new aminosugars of differing types, for example of two monoamino-tetroses (12,19), nineteen monoamino-pentoses, two diamino-pentoses, thirty-three monoamino-hexoses, and eighteen diamino-hexoses (20) have been accomplished. It is well undterstood that the aminosugars, significant constituents in mnay biologically important materials (11), consist of substances that may be regarded a teh condesation products of an amine and a carbohydrate. Falling into this category are the 2-amino-hexoses which may be derived conceptually as the condensation …

Studies On The Rates Of Mutarotation Of The Benzyl-N-Carbobenzoxy-D-Glucosaminides, Kamthorn Sukumarabandhu

University of the Pacific Theses and Dissertations

The independent interconversion of alpha-N-carbobenzoxy-D-glucosaminide to the beta- form, and vice versa, suggests that the proper treatment of the rate data must involve a system of opposing reactions. It is evident from the data cited in the preceding chapter that such opposing rates must necessarily involve the HCl which is included in the reaction mixture. Thus, as the first approach to the analyzed data, it is reasonable to suppose that the rate law for opposing second-order rates will apply. However, it is also apparent from the data that the concentration of HCl used in all this work exceeds the glycoside …

A New Two-Position Protecting Group: Preparation And Properties Of Glucopyranosido-(1,2: 4',5')-2'-Oxazolidone And Syntheses Of D-Glucosaminides, Sharad Ramchandra Kulkarni

University of the Pacific Theses and Dissertations

The present work consists of two parts. The first part contains the synthesis of 3,4,6-tri-o-benzoyl-D-glucopyranosido-[1,2:4¹,5¹]-2¹-oxazolidone (III) and the study of its chemistry in order to determine whether it could be used as a simultaneous protecting group for C₁ and C₂ in the preparation of new aminosugars. The second part covers the synthesis and de-o-benzoylation of β-D-glucosaminides. The products thus obtained can be used to prepare new disaccharides. In addition new aminosugar derivatives have been prepared.

Thermal Hydrolysis And Structure Studies On Cobalt (Ii) Acetate, Russell J. Hesch

Masters Theses

"The object of this study was to investigate the structure of cobalt (II) acetate, isolated from glacial acetic acid, without recourse to standard x-ray methods"--Introduction, page 1.

Carcinostatic Sulfonic Acid Esters Of Selected 1,4-Diols, Robert A. Earl

Masters Theses

Introduction

The purpose of this research was to prepare the bisarylsulfonic acid esters of 1,4-butanediol and 1,4-but-2-ynediol.

This series of compounds is of interest because of the antitumor activity exhibited by the bismethanesulfonates of 1,4-butanediol and 1,4-but-2-ynediol. The compounds which were prepared were submitted to Cancer Chemotherapy National Service Center for evaluation in their anticancer program.

It was hoped that the compounds synthesized would be of pharmacological value. It was further hoped that the biological test data of these compounds would demonstrate a correlation between types of substituents on the aromatic nucleus and the degree of activity of the compounds. …

I. An Investigation Of The Organic Compounds In The Media And Mycelium Of Naucoria Confragosa. Ii. Study Of The Extra-Cellular Pigments Of An Unknown Fungus, Yueh-Tsun Chen

Masters Theses

"The fungal metabolites excreted into the culture fluid by basidiomycetes growing on synthetic glucose media as well as formed in the mycelia of the organisms were investigated in this thesis. Earlier unpublished work had shown that Maucoria confragosa excreted into the medium compounds which were thought to be phenols. Insufficient material was recovered from an ethyl acetate extract of the medium in the present study for further investigation. Colorimetric methods were employed both for the quantitative estimation of reducing sugar not consumed by the microorganisms as well as for a measure of the total organic solids present in the spent …