Physical Sciences and Mathematics Commons^™

Synthesis Of 3-(P-Methyl-M-Nitro-Phenyl)-Butyric Acid, Beverly Thomas Adams

Honors Theses

The purpose of the research reported in this thesis was the synthesis of one of a class of compounds, ω-napthyl-alkyl-substituted nitro benzaldehydes, for use in later work involving photochemistry. The compound chosen was p-(ω-naphthyl-propyl-)-2-nitro-banzaldehyde.

A Polarographic Analysis Of The Tetracyanoaurate (Iii) And The Dicyanoaurate (I) Complexes, David Jefferson Mcclemens

Honors Theses

A polarographic analysis of the two gold complexes, dicyanoaurate (I) and tetracyanoaurate (III), was undertaken. Both complexes were shown to have distinguishable current-voltage curves. Previous work on the dicyanoaurate (I) was confirmed, and new data was added for the low concentrations. The tetracyanoaurate (III) was investigated, and the half-wave potential was found to be -0.32 volts. Maxima problems with the complex were encountered and resolved.

Edta Titrations With Mercury Amalgam Indicator Electrodes, Kenneth Deardorff Legg

Honors Theses

A study of the characteristics of certain mercury amalgam electrodes as used in these types of analysis has been made. The overall applicability and usefullness of a bismuth-mercury slurry electrode is studied. The effect of several solution conditions on the electrode characteristics has been observed.

Molybdenum-L-Histidine Complexes, Jiing-Yun Lee

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

L- Histidine is a very important amino acid and is widely distributed in living systems. In the growth and multiplication of animal cells, it was found that L-histidine is one of the amino acids that must be present. From the kinetic studies of certain enzymes such as chymotrypsin and ribonuclease, it has been proposed that the imidazolyl group of the histidine residue may serve as the basic electron donor, and that the histidine residue in some cases may be the active site of the enzyme. The interactions of L-histidine with heavy metal ions, including Ni (II) (1), Zn (II) (1, …

The Synthesis And Reactions Of 6-Carboxy Isatoic Anhydride, Jacqueline I. Kroschwitz

Chemistry Honors Papers

This 27 page thesis researches the preparation and characterization of 6-carboxy isatoic anhydride and the study of the reactions of this compound, leading to the synthesis of a series of compounds of new composition.

A Calorimetric Study Of Metal Amino Acid Complexes In Aqueous Solution. I. The Copper (Ii) Glycine System. Ii. The Nickel (Ii) Glycine, Alanine And Phenylalanine Systems, Wilbur Orme Greenhalgh

Theses and Dissertations

Calorimeter values were obtained for the standard enthalpy change for the following reactions at 10,25, and 40 degrees C.: 1. The dissaciation of the amino acid, glycine, in the zwitterion form (HA) to give the basic form (A-) and a proton. 2. The reactions of copper (II) ion with glycine to form the Cu gly+ and Cu (gly)2 complexes. 3. The reactions of nickel (II) ion with glycine and alanine to form Ni gly+, Ni (gly)2, Ni al+, and Ni (al)2 complexes. For calorimetric enthalpy calculations, the initial and final concentrations of all species in the calorimeter must be known; …

The Pyrolysis Of Menthol, John James Westbrook Iii

Master's Theses

Research on the pyrolysis or organic compounds has received an increasing amount of attention in recent years. The pyrolysis of terpene hydrocarbons has been of interest primarily because of their wide-spread and abundant natural occurrence. In addition terpenes have been investigated because of their interesting stereochemistry.

Menthol is a C₁₀ monocyolic terpene alcohol. Its thermal decomposition at temperatures greater than 500°C has not been investigated previously because of inadequate methods of analysis.

The pyrolysis of other terpene hydrocarbons has revealed new routes to useful intermediates from relatively cheap source materials. Menthol, however, has never been considered as a possibility …

"Equilibria In Solution" : 2,2,8,8-Tetrakishydroxymethyl-3, 7-Diaza-1, 5,9 -Nonanetriol And 2,2,8,8-Tetramethyl-3, 7-Diaza-5-Nonaneol With Copper (Ii), Ronald Weston Davis

Master's Theses

The chelating agents, 2, 2, 8, 8-Tetrakishydroxymethyl1-3, 7-diaza-1, 5, 9-nonanetriol (''Disec") and 2, 2, 8 ,8-Tetramethyl1-3, 7-diaza-5-nonaneol ("Symaminol") were prepared and investigated with respect to their Basicity and Stability Constants.

The compound, "Disec," investigated in earlier work was again studied using more precise and controlled conditions of temperature (30.000 + - 0.002°C), measured pH readings and volume readings.

Tbe compound, "Symaminol," was prepared in the laboratory and studied in the same manner as "Disec." Examination of the literature yielded no evidence of "Symaminol" having been previously investigated.

By means of a digital computer, the data was correlated in a manner …

Potential Diuretic Agents;The Synthesis Of 4, 7-Disubstituted Derivatives Of 2-Phenylimidazo [4, 5-D]Pyridazine., Miriam P. Malm

Chemistry and Chemical Biology ETDs

"The maintenance of the water balance of an organism is of prime importance for its physiologic well-being." (1) Water, which composes approximately two-thirds of the entire human body weight, is the fluid in which all vital chemical reactions occur. A loss of 25 percent of body water usually proves fatal. The inherent physical and chemical properties of water render it as the ideal fluid to meet the physiological demands of the organism.

Studies In The Behavior Of Certain Cyclic Olefins Toward Divalent Platinum And Palladium, Ernest Sam Juljian

University of the Pacific Theses and Dissertations

The initial program of study for consideration was the extension of cyclooctatetraene complexation to other metals of the transition group. Compounds of (COT) with iron, cobalt, chromium, molybdenum, and tungsten which have been reported in the literature involve carbonyl ligands simultaneously as (COT)M(CO)_x with x = 2,3----; only Ag(I) as AgN03 adducts are known. Rhodium (I) is said to form an unstable dimer while ruthenium (I) forms a polymer. (COT)Pt(II) chloride, bromide and iodide have been reported but only the iodide has been studied; only (COT)PdCl₂ has been reported recently. It was further conceived that substituted (COT) would …

Put Garden Rubbish To Work In A Compost Heap, W Dawson

Journal of the Department of Agriculture, Western Australia, Series 4

THERE'S a surprising amount of mumbo jumbo written about the simple compost heap. By the time you've waded through all the instructions, you feel as if you ought to have prerequisites of a doctorate in soil chemistry or an unbroken ancestry of at least three generations of professional English gardeners.

The Reaction Of Ketosemicarbazones With Lead Tetraacetate, Thomas M. Davies

Masters Theses

Introduction

It has been demonstrated that lead tetraacetate will oxidize ketohydrazones to azoacetates in good yields (11).

R₂C=N-NH-R + Pb(OAc)₄ ------> R₂C(OAc)-N=N-R + Pb(OAc)₂ + HOAc

Since ketosemicarbazones are structurally equivalent to ketohydrazones, it was thought that the reaction of ketosemicarbazones with lead tetraacetate would proceed in a similar manner. Originally the object of this research was to prepare a series of new azo compounds related to semicarbazones by lead tetraacetate oxidation.

Pachycereus Marginatus Alkaloids, John M. Brewer

Masters Theses

Introduction

Serturner's paper, 1817, "Morphis, a New Salt-forming Substance, and Meconic Acid, as the Chief Constituents of Opium", opened a new era of discovery in organic plant chemistry. His isolation of the first alkaloid was soon followed by the isolation or narcotine by Robiquet and strychnine by Pelletier and Caventou. These basic compounds were at first called vegetable alkalies, but were later renamed alkaloids, meaning alkali-like¹¹.

The Protein Of Phleum Pratense, Clifford A. Dean

University of the Pacific Theses and Dissertations

As the chemist increases his knowledge and understanding of the complex and delicate nature of the proteins, many of the methods which are used in the handling and treatment of protein systems need to be reviewed and reexamined in the light of the new information which is now available.

This study has endeavored to take the biologically active protein system from the pollen or timothy grass (Phleum pratense) and examine its stability under currently used methods of extraction, purification, and storage.

New chemical agents were studied in connection with the above mentioned protein tor their possible use in the place …

A Study Of The Platinum (Ii), Palladium (Ii), And Rhodium (Iii) Chelates Of Aspartic And Glutamic Acid, Cecilia Elizabeth Luschak

University of the Pacific Theses and Dissertations

It is fairly well known that alpha-amino dicarboxylic acids combine quite readily with basic metal ions such as the alkaline earths. The nature of the problem includes the synthesis and characterization of six platinum metal chelates of two alpha-animo dicarboxylic acids, namely aspartic and glutamic acids. The metal ion upon which the investigation is focused are platinum (II), palladium (II), and rhodium (III). Several of these are reported as having been repaired. The series is incomplete, however, and little study has been done correlating the abilities and trends of the complexes as a function of the metal ion and carbon …

Chalcone Derivatives From Pyrrole-2-Aldehyde, Ahmad Hamidi

University of the Pacific Theses and Dissertations

Claisen first synthesized Chalcone in 1881 by condensing acetophenone with benzaldehyde using sodium methoxide as a condensing agent. Chalcone and its derivatives have been prepared primarily as intermediates for the synthesis of anthocyanins and other related pigments.

In recent years extensive preparation and study of chalcones has been carried out utilizing chalcones for their biological effects in medical and pharmaceutical fields. It has been shown that certain highly substituted compounds present in the flower pigments as additives to adhesive absorb ultraviolet radiation. Carboxylic acid chalcones have become known for their therapeutic action in the treatment of chronic kidney diseases, diseases …

The Transition Metal Complexes Of Anthranilic Acid And Its Derivatives, Jesse Smith Decker

University of the Pacific Theses and Dissertations

Part of this investigation was undertaken to determine the effects of functional group substitution on the ring - as well as on the -NH₂ radical - on the formation of metal complexes with the first transition series in the periodic classification of the elements.

The outline of the investigation in this report is as follows: (1) To mind methods for the preparation of the complexes.; (2) To examine the relative ease of formation, and the relative solubility of such chelates in common laboratory reagents.; (3) To determine the relative stabilities by relative molar conductance measurements.; (4) To discover relative …

Controlled-Potential Polarography In Liquid Ammonia: Inorganic Half-Wavepotentials, Ronald Alan Head

University of the Pacific Theses and Dissertations

The literature of polarography is so vast that any new publication in the field is likely to have an impact comparable to that of a raindrop falling on an ocean. If, however, through some alchemy of the imagination, the raindrop transformed to quicksilver and accompanied by discharge of "lightning"; and the "ocean" be a solution under carefully controlled conditions, then the effect may be measurable--even reproducible--and thus subject to rational interpretation. Since Jaroslav Heyrovsky's pioneer work in the early nineteen twenties, many such drops have fallen, bringing the science and art of polarography to its present highly developed state. Though …

Solubility And Structure Studies Of Nickel (Ii) Acetate, Richard J. Baird

Masters Theses

"The effects of ammonium acetate on the solubility of anhydrous nickel (II) acetate in anhydrous acetic acid was investigated and was found to behave similar to the zinc (II), copper (II), and cobalt (II) systems. Problems with equilibrium, encountered by previous investigators, were overcome. The determination of the structure of nickel (II) acetate hemiacetate was atacked by infrared studies, preparation of adducts, cryoscopic studies, magnetic susceptibility measurements, and absorption spectra. It was found that nickel (II) acetate hemiacetate is octahedrally coordinated with two coordination sites vacant. It was shown that the binuclear cage structure common to copper (II), chromium (II), …

Distribution Of Sodium Perchlorate Between Tributyl Phosphate And Water, John A. Tengler

Masters Theses

"The questions posed by Carroll (23) concerning a TBP-H₂O system and an alkali salt -which is appreciably soluble in TBP have been partially answered by the experiments described in this thesis"--Conclusions, page 38.

Correlation Between Drying Times Of A Vinyl Copolymer Solution And Properties Of Dried Films., Abd El-Rahman M. Naser

Masters Theses

"One of the common methods used in film formation is the solvent evaporation method. As the evaporation starts the viscosity increases due to the inability of the solvent to keep the chains apart, which leads to a drag between molecules.

The rate of evaporation of the solvent (loss of solvent) cannot be equated with the rate of drying, since the latter depends on the results of the loss of solvents in terms of viscosity and plastic properties. The drying time can be defined as the rate at which a film increases its viscosity and thus changes the properties of a …

Some Quadrivalent Compounds Of Rhenium And Technetium Containing Fluorine, David E. Lavalle

Masters Theses

The work in this laboratory was begun with the aim of producing pure K₂ReF₆, as a possible intermediate in the preparation of the lower fluorides of rhenium and as a "stand-in" for the preparation of K₂TcF₆. It meant, therefore, the preparation of the white form of K₂ReF₆ which both Weise and Peacock had described as the pure form of the compound.

I. Preparation And Properties Of Alkyl And Aryl Substituted Thioquinazolines And Sulfoxides ; Ii. An Investigation Of The Quinazoline 3-Oxide--1,4-Benzodiazepine 4-Oxide Rearrangement, Marvin C. J. Kuchar

Theses and Dissertations

I. The quinazolines, a branch of the benzodiazine class of aromatic nitrogen hetercycles, do not occur to any great extent in naturally occurring compounds. The discovery of the antimalarial febrifugine and its structure elucidation led to the preparation and investigation of a host of new quinazolines in the search for new and more effective antimalarials. Most of the present body of information governing the quinazolines arose out of these synthetic studies. The present study has been accomplished with a four-fold purpose in mind: (1) to investigate the susceptibility of chloroquinazolines to nucleophilic displacement reactions by thiols or their salts, (2) …

Energy Migration In Rare Earth Complexes, John Jerome Freeman

Chemistry and Chemical Biology ETDs

Complexes of trivalent samarium, europium, terbium, and dysprosium were prepared for investigations of the luminescence properties of complexed rare earth ions. Rare earth chilates derived from benzoylacetone, dibenzoylmethane, and acetylacetone; rare earth chlorides solvated with water and deuterium oxide; and rare earth oxides dissolved in sodium metaphosphate glasses were synthesized for these studies.

Radiochemical Studies: Isotopic Exchange Reactions, Solvent Effects, Preparation And Properties Of Carrier-Free Amalgams, Hans L. Hamster

Chemistry and Chemical Biology ETDs

The work described in this section is concerned with the kinetics of an S_N2 reaction, the isotopic exchange reaction between iodide ions and p-nitrobenzyl iodide, carried out in an aprotic solvent, acetone, in the presence of various substituted phenols and anisole. This reaction was carried out at concentration of potassium iodide low enough to insure the absence of ion pairs.

6th Annual Rocky Mountain Spectroscopy Conference Program

Rocky Mountain Conference on Magnetic Resonance

Program from the 6th annual meeting of the Rocky Mountain Spectroscopy Conference, sponsored by the Rocky Mountain Section of the Society for Applied Spectroscopy. Held in Denver, Colorado, August 12-13, 1963.

6th Annual Rocky Mountain Spectroscopy Conference Reply Card

Rocky Mountain Conference on Magnetic Resonance

Reply Card for the 6th annual meeting of the Rocky Mountain Spectroscopy Conference, sponsored by the Rocky Mountain Section of the Society for Applied Spectroscopy. Held in Denver, Colorado, August 12-13, 1963.

6th Annual Rocky Mountain Spectroscopy Conference Abstracts Of Papers

Rocky Mountain Conference on Magnetic Resonance

Abstracts of papers presented at the 6th annual meeting of the Rocky Mountain Spectroscopy Conference, sponsored by the Rocky Mountain Section of the Society for Applied Spectroscopy. Held in Denver, Colorado, August 12-13, 1963.

A Modified Procedure For The Quantitative Determination Of Fluoride And The Application Of This Procedure To A Fluoride Balance Study In Children, Beatrice Shuang Wu

Masters Theses

Introduction

This research problem was done in connection with the fluoride balance studies on twelve children at Plymouth State Home. The retention balance studies of fluoride by children can be studied indirectly by measuring the amounts of fluoride excreted in the urine and feces after administration of the fluoride in water or in vitamins as sodium fluoride. The fluoride balance study was repeated, because in the previous study (19), there were no samples collected for a base day in which the fluoride was not given. The previous data also indicated that fluoride retention was merely a function of the interval …

Thermodynamics Of I) Metal Cyanide Coordination, Ii) Water Formation, And Iii) Metal Halide Coordination, John Dewey Hale

Theses and Dissertations

ΔH values for the formation of Ni(CN)4(aq)= have been determined calorimetrically at 25° using a simple calorimeter and a thermometric titration procedure at high and low ionic strengths, respectively. Extrapolation of these ΔH values to infinite dilution resulted in a ΔH° value of -42.7 kcal./mole. Combination of ΔH° and ΔF° values gives a ΔS° value of -5.5 e.u. for Ni(CN)4(aq)= formation. A value of +70 e.u. is calculated for the ionic entropy of Ni(CN)4(aq)=. A preliminary investigation of the Zn(CN)4(aq)= system indicated the existence of zinc cyanide complexes other than Zn(CN)4= and allowed calculation of an approximate ΔH° value of …