Physical Sciences and Mathematics Commons^™

Perspectives In Hospital Pharmacy Design Based On Functional Requirements, Robert Kenneth Overend

University of the Pacific Theses and Dissertations

It is significant that the separation of pharmacy from medicine occurred for the first time in institutions under ecclesiastic authority which were devoted to the care of the sick. In this period of history, there was little division between the church and state; therefore, business did not play any part in the overall health care scheme. The prime consideration was the delivery of the highest quality of pharmaceutical and medical services. This was best accomplished by a division of labor between the expert in the medical treatment and the expert in the selection, preservation and prepagation of medicinals. In other …

The Formulation And Physical Analyses Of Antibiotic Aerosol Foams For The Development Of Potential Topical Dermatologicals, Joseph Alexander Woelfel

University of the Pacific Theses and Dissertations

Within the last two decades the consumer market has been deluged with a diversity of aerosol products. The acceptability and utility of these products is reflected by the number found in the household and industry.

An antibiotic foam would obviate the necessity of manual application as is the case with the ointment or cream type products. Therefore, there would be less irritation to the already traumatized or infected sites by mechanical, chemical, or bacterial vectors.

Thus, the objective of this research will be to systematically develop suitable aerosol foam systems which contain therapeutically effective topical antibiotics with a subsequent evaluation …

Spectrophotometric And Microbiological Determination Of The Stability Of Sodium Ampicillin As Affected By Ph, Enrico Frank Raffanti

University of the Pacific Theses and Dissertations

The specific purpose of this investigation was to determine the effect of pH on the stability of ampicillin sodium for injection. Then, to correlate this information, a pH profile may be established to predict chemical stability with ampicillin sodium alone or when other drugs may be included in the admixture. With a pH profile the pharmacist could predict the length of time after which more than a 10 percent loss of activity would occur. Stability measurements were to be accomplished through a microbiological assay after adding ampicillin sodium to different buffer solutions. At the end of four hours, eight hours, …

Metabolic Role Of Sulfates And Sulfides Producing Bacteria In Pollution Of Waters, M. I. H. Aleem

KWRRI Research Reports

Cytochrome transport particles from Nitrobacter catalyzed nitrite, ascorbate as well as NADH oxidation with concomitant phosphate esterification yielding P/0 ratios of 1.0, 0.6 and 2.0 respectively. Phosphorylation coupled to nitrite oxidation was not effected by rotenone, amytal or antimycin while 50 and 70% inhibition of the NADH-linked phosphorylation was observed in the presence of HOQNO and rotenone respectively. Cell-free extracts from Nitrobacter also catalyzed an energy-dependent reduction of NAD⁺ by nitrite. The reduction of cytochrome c by NŌ₂ was energy-dependent which involved the reversal of electrons from cytochrome a₁. The subsequent energy-linked reduction of the flavoproteins …

Sero-Epidemiology Of Q Fever With Special Reference To Complications In A Hospital Population Of Southern California, Ajit Singh Randhawa

Loma Linda University Electronic Theses, Dissertations & Projects

[Abstract Not Included]

The Effects Of A Topically Applied Anti-Inflammatory Agent On Root Resorption In The Replanted Teeth Of Canines, William L. Young

Loma Linda University Electronic Theses, Dissertations & Projects

Root resorption is a constant finding on the roots of replanted teeth. In this study it was suggested that root resorption is perhaps related to inflammation and that teeth incubated in an anti-inflammatory agent such as triamcinolone acetonide, a corticosteroid, before replantation would have less resorption. To investigate this hypothesis nineteen mature teeth in five mongrel dogs were extracted and replanted. Ten of the teeth were incubated for five minutes in the steroid and nine control teeth for the same period in a saline solution. Before euthanizing the animals at one, three, five, and seven weeks, a clinical evaluation of …

The Effect Of Early Postpartum Teaching Of Infant Feeding On Maternal Concern, Linda M. Richter, K. Judy Toews

Loma Linda University Electronic Theses, Dissertations & Projects

An experimental study was conducted on thirty primiparae during the postpartum period to determine if individualized instruction regarding infant feeding would result in a lower level of maternal concern in this area. The study sample was randomly and evenly divided into a control and an experimental group. It was statistically determined that the two groups were homogeneous in regard to age, education, occupation, previous information (prenatal classes and reading) and help at home. The experimental group received individualized instruction by the researchers concerning their chosen method of infant feeding on the second postpartum day. There was no instruction given the …

A Comparison Of Various Teaching Methods For Patients With Chronic Obstructive Pulmonary Diseases, B. Carol Altizer, Nancy S. Bailey

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to find out whether patients with chronic obstructive pulmonary disease (C.O.P.D.) learn more from auditory or from visual teaching. Of the 30 patients in the sample, 10 used a programmed instruction booklet, 10 used a taped recording of the same programmed material and 10 were in a control group which received no specific teaching.

A pre-test was given to each of the patients who met the criteria for the study. One researcher gave the pre-test through an oral interview with the patient. After the pre-test, the patient received the teaching device assigned to him …

Using A Participating Relationship To Improve Teen-Age Unwed Mother's Self-Esteem, Linda Gail Reeves

Loma Linda University Electronic Theses, Dissertations & Projects

The study was to provide an approach to help teen-age unwed mothers increase their feelings of self-esteem and thereby attain a conceptual buffer for better coping with life. Self-esteem was defined as individual perception of the worth of oneself relative to that of significant others. The hypothesis tested was that the participating relationship a community health nurse has with a teen-age unwed mother will significantly increase the mother's self-esteem as measured by statistical Q-Sort analysis.

A convenience sample of twenty teen-age unwed mothers was obtained from referrals from San Bernardino County Health, Welfare, and Probation Departments. The girls were between …

A Computerized Study Of Midpalatal Suture Expansion, Clelan G. Ehrler

Loma Linda University Electronic Theses, Dissertations & Projects

An investigation has been conducted to consider the effects of midpalatal suture expansion on the cranial-facial complex. Nine patients were treated that had constricted maxillae. Data was obtained from frontal and lateral headplate radiographs which were taken at four intervals during treatment. The Rocky Mountain Data Systems diagnosis was utilized to interpret the radiographic data.

The data from the nine cases were averaged to obtain a composit [sic] change at each of the four times.

Examination of the lateral headplate data revealed that no permanent significant alteration occurred to the positions of the mandible or maxilla in a vertical or …

Relationship Of Ventilation Ability And Positioning In Left-Sided Congestive Heart Failure Patients, Nancy E. Carson

Loma Linda University Electronic Theses, Dissertations & Projects

Proper positioning is used to relieve dyspnea, edema, and fatigue in congestive heart failure patients. According to the review of literature, improved ventilation as measured by specific lung volumes and lung mechanics occurred with upright positioning in normal persons. The effects of specific changes in lung volumes related to position change in congestive heart failure patients has not been documented in literature, although various recommendations related to positioning are made. This exploratory study was undertaken with nine congestive heart failure patients to see if a relationship existed between degree of head elevation and lung ventilation ability as measured by water-bell …

Procedures For Trace Analysis Of Dissolved Inorganic And Organic Constituents In Water, Gary D. Christian, Charles E. Matkovich, W. Lynn Schertz

KWRRI Research Reports

A study of different solvent systems for the atomic absorption determination of cobalt revealed that acetone results in best sensitivity. Acetone is the solvent of choice for the sensitive measurement of several metals. Hence, methods were investigated for the separation of acetone from water by salting out so that possible solvent extraction of metal chelates into this solvent could be performed. About two-thirds saturated calcium chloride proved to be the best system for salting out of the acetone. It is essentially a neutral salt and is in general a weakly complexing salt, resulting in minimum interference in solvent extractions. Solvent …

The Effects Of Indomethacin On A Strain Of Fibroblasts Cultivated In Vitro, John Thomas Mccloskey

University of the Pacific Theses and Dissertations

Man has always searched for greater understanding of himself and his environment. As a result, much scientific investigation has been directed towards the understanding of the life process. In recent years, such scientific inquiry has become increasingly focused on the fundamental biochemical events taking place at the cellular, subcellular, and molecular levels. In the course of investigation into the nature of living things, research has often necessitated the development of new techniques and investigational tools to serve as experimental systems. Very often such new methods have made possible the discovery of previously unknown processes. One very interesting and useful investigational …

Influence Of Hospital Communication On Health Supervision Of High-Risk Infants, Alda L. Forte

Loma Linda University Electronic Theses, Dissertations & Projects

The study was conducted to explore the extent to which communication about high-risk infants identified prior to hospital discharge, influences the public health nursing supervision to these infants during the neonatal period. A high-risk infant was defined as one that stands a greater than average chance of developing neonatal, life threatening disease or sequellae (physical, intellectual, or social handicap) due usually to maternal health or social factors, infant factors such as length of gestation, birth trauma, or complications at birth. The hypothesis tested was that when high-risk infants are identified prior to hospital discharge and this information communicated on the …

Depression And Uncooperativeness In Public Health Patients, P. Sherrill Baugher, Nancy Lynn Swan

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine whether uncooperative behavior and a quantitative measurement of depression exist in the same patient in a public health nurse's caseload. Seven full-time public health nurses were randomly selected from the San Bernardino Public Health Department staff. They reviewed their caseloads and selected all the patients who met the general criteria.

Patients were then classified as cooperative or uncooperative based on the following specific criteria: (1) gives unreliable information, (2) uses the nurse as a "buffer" between helping agencies, (3) demands immediate gratification of requests in a stressful situation, (4) makes only token …

Algal Growth And Decomposition: Effects On Water Quality, Phase Ii, Edward G. Foree, Ronald L. Barrow

KWRRI Research Reports

The decomposition and associated nutrient regeneration of three unialgal cultures and one mixed culture containing an indigenous population of bacteria and microscopic animals were studied under dark, constant temperature laboratory conditions. After periods of nutrient-deficient growth ranging from O to 30 days, these cultures were inoculated with decomposer populations and subjected to anaerobic and aerobic environments for the decomposition studies. The extend of decomposition was determined from the percentage volatile suspended solids and percentage particulate COD remaining after 200 days of decomposition. The average extent of decomposition was greater for aerobic than for anaerobic conditions. However, significant portions of the …

Labor Time Analysis By Work Function Activity In Production Of Vegetarian Entrees, Maynard W. Lebrun

Loma Linda University Electronic Theses, Dissertations & Projects

The specific objectives of this research were to (1) develop a method for determining labor time and labor cost of cooks by work functions in the production of selected vegetarian entrees, and (2) determine the percentage relationship of cooks' labor to food cost in selected classifications of entrees.

Application of the continuous time study methodology as developed in this research was restricted to the observation of entree cooks in a 408 bed non-profit university hospital. Observation of work function activities during the first week of a four week cycle menu for three consecutive cycles was classified under three major categories: …

An In Vivo Perfusion Apparatus For Studies On Gingival Disease In The Albino Rat : Assessment By A Perfusion Of The Enzymes Collagenase And Hyaluronidase, James A. Smith

Loma Linda University Electronic Theses, Dissertations & Projects

This thesis describes an in vivo perfusion apparatus which can continuously deliver controlled quantities of solutions to localized, contralateral intraoral areas in albino rats. Three animals were per fused on the experimental area (the mesial sulcular area of the maxillary first molar) on one side with tap water and Trypan blue. Localization of the solution delivered and minimal histological changes due to the presence of the apparatus was demonstrated on these animals. Solutions of .5%, 1%, and 2% hyaluronidase and collagenase were perfused on the experimental areas of nine animals. When both enzymes were used, hyaluronidase always preceded collagenase in …

Periodontal Pocket Reduction Following Gingival Curettage, Robert B. Tandy

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to evaluate pocket reduction following gingival curettage. The effects of temporary pressure packing, inflammation, oral hygiene, pocket depth, age and sex of the patient were evaluated.

Three hundred twenty-eight periodontal pockets were studied in forty-one adult patients selected with interdental lesions ranging from 3.0 - 7.5 mm. in depth. Pocket depth and gingival height were measured preoperatively, one month postoperatively and two months postoperatively. The mean change in pocket depth and gingival height was calculated and statistical significance was determined for all measurements.

The results show that after a two-month postoperative evaluation following gingival …

A Study To Demonstrate The Immediate Destination Of An Embolus Formed In The Lumen Of A Peripheral Venous Catheter, Rosemarie Morikone Emori

Loma Linda University Electronic Theses, Dissertations & Projects

This study was designed to show the immediate destination of an embolus formed in the lumen of an intravenous catheter placed in a peripheral vessel. The hypothesis stated that clots injected into a peripheral vessel will lodge in the lungs. A subhypothesis was that the clot may lodge anywhere along the circulatory pathway.

Indications of need for the study as shown by the review of literature were the following: (1) the complications resulting from the frequent use of intravenous polyethylene catheters, (2) experimental studies that showed that clots were formed around intravenous catheters, (3) the evidence that intravenous catheters predispose …

An Analysis Of Orthodontic Treatment Results Employing Class Ii Armstrong Adjustable Intermaxillary Springs, Michael E. Shumate

Loma Linda University Electronic Theses, Dissertations & Projects

A study of orthodontic treatment results employing Class II Armstrong Adjustable Intermaxillary Springs was made on twenty-eight randomly selected patients which were treated by Dr. Maclay Armstrong.

The skeletal and dental changes observed during treatment with the Class II springs was compared with those results observed when comparable type malocclusions were treated with Class II elastics. A list of changes which were observed during treatment with Class II elastics was compiled from the literature using individual studies published by Ricketts, Creekmore and Hanes.

The study was based on the findings observed in the initial and final cephalometric radiographs. A statistical …

A Comparative Roentgenographic Cephalometric Study Of The Facial Profile Of Orthodontic Patients Treated At Loma Linda University With Winners Of The "Smiles Of The Year" Contest, Romeo I. Stoll

Loma Linda University Electronic Theses, Dissertations & Projects

The "Smiles of the Year" winners and patients treated at Loma Linda University by the extraction or non-extraction approach were compared by linear and angular variables of skeletal, dental and soft tissue components. These findings were analyzed statistically to determine significant differences in the profile and detect the relationship between the integument and hard structures.

The following conclusions were drawn from this investigation to reflect the trend of treatment at Loma Linda University.

1. After treatment the patients had less skeletal convexity, but were more convexity than established standards.
2. The incisors of the patients treated by the extraction approach were less …

Ecological Planning Workshop Poster April, 1970, Ian Mcharg, Risd Archives

Ecology and Environment

Ecological Planning Workshop Poster by Ian McHarg. April 24, 1970, RISD Auditorium.

The Pharmacology Of Rodenticides, S. A. Peoples

Vertebrate Pest Conference Proceedings: 4th (1970)

The compounds used as rodenticides are tremendously varied in their chemical structure and mechanism of action. With a few exceptions, these agents are generally poisonous to all animals, including man, and a great deal of study has been directed to their toxicity in animals other than rodents. However, the development of new compounds as Norbormide and certain antifertility drugs which are highly selective in their action may justify the hope that the ideal rodenticide free of secondary toxic hazards will soon be available. Until this happy announcement is made, a review of the pharmacology of the older compounds is in …

Algal Growth And Decomposition: Effects On Water Quality, Edward G. Foree, John S. Tapp Jr.

KWRRI Research Reports

The chemical composition of algae grown in batch culture depends mainly on environmental conditions, nutrient availability, presence of predators, cell age, and species. The effects of nutrient availability and cell age on the composition of three unialgal cultures (algae + bacteria) and one hetergeneous culture (algae + bacteria + microscopic animals) were evaluated. The cultures were grown in batch culture under both nutrient-abundant and nutrient deficient conditions and the changes in compositions were observed. Luxurious uptake where nutrients are incorporated into cellular protoplasm at levels greater than those necessary for growth, and super-luxurious uptake, where some nutrients are stored rather …

Proceedings Of The Arkansas Academy Of Science - Volume 24 1970, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

The Effect Of Removing The Crevicular Epithelium Upon Canine Tooth Replantation, Leon A. Leonard

Loma Linda University Electronic Theses, Dissertations & Projects

The nature of epithelium and the remarkable facility with which it aggressively covers granulation tissue, suggests that removal of the sulcular epithelium surrounding the extraction wound of a tooth to be replanted could promote reattachment of the periodontal tissues at a more nearly ideal coronal level. To investigate this hypothesis twenty mature teeth in five mongrel dogs were experimentally replanted. One half of them were replanted in alveoli around which the crevicular epithelium had been removed, the remaining teeth without creviculoectomy acting as controls. Animals were euthanized at one, two, three, five, and sixteen weeks. After clinical evaluation of the …

A Historical Study Of The Nursing Care Of The Newborn Infant In The Hospital Nursery, Synnove Wasli

Loma Linda University Electronic Theses, Dissertations & Projects

This was a historical study of past ideas, beliefs, and practices in the nursing care of the normal newborn infant in the hospital nursery. The study covered the years 1930 to 1965 and was divided into four cross sections, namely, 1930 to 1935, 1940 to 1945, 1950 to 1955, and 1960 to 1965.

The primary sources used in this study consisted of one hundred infant medical records which were made available by a 382-bed, private, general hospital located in a Los Angeles suburb. One procedure manual used in this hospital during the years 1944-1955 qualified as a primary source. Personal …

The Effect Of Selected Nurse-Patient Contacts On The Attendance Of Non-Private Patients At Preparation For Childbirth Classes, Judith A. Hart

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to determine whether selected nurse-patient contacts effected the attendance of non-private patients at Preparation for Childbirth classes. During the data collection period only six of the eight patients who met the criteria for this study were available. Each of the six patients was reached by at least one of the three types of nurse-patient contacts-- a letter of invitation to the Preparation for Childbirth classes, weekly contacts with the patients at the classes and three home visits to each patient. Tools used to collect data for this study were a personal information questionnaire, home …

Study To Save Block Island, Designer's News, May 19,1969, Students Of Risd, Risd Archives

Ecology and Environment

RISD Landscape Architecture Study to Save Block Island Article from Designer's News, May 19, 1969 student newspaper.