Physical Sciences and Mathematics Commons^™

Design, Synthesis And Applications Of Nanoparticles In Suppression Of Mosquito-Born Flaviviridae Viruses, Maria R. Blahove

Electronic Theses and Dissertations

Recently, nanoparticles have become an origin of exploration in the chemistry field due to their unique medical uses. The current drug delivery models of nanoparticles often include a metal base with a drug conjugated to its surface. However this raises concerns regarding toxicity. A novel approach to solving this dilemma is the development of nanosized biocompatible polymer-based micelles, created from PEG-PCL-PEG triblock polymer, and formed around a drug of choice. The goal is to create a drug carrier nanoparticle system that is labile at a specific intracellular pH, without undue toxicity to the cell. This creates a drug-loaded nanoparticle that …

A Study Of Factors That Influence Symbol Selection On Augmentative And Alternative Communication Devices For Individuals With Autism Spectrum Disorder, William Todd Dauterman

CCE Theses and Dissertations

According to the American Academy of Pediatrics (AAP), 1 in 59 children are diagnosed with Autism Spectrum Disorder (ASD) each year. Given the complexity of ASD and how it is manifested in individuals, the execution of proper interventions is difficult. One major area of concern is how individuals with ASD who have limited communication skills are taught to communicate using Augmentative and Alternative Communication devices (AAC). AACs are portable electronic devices that facilitate communication by using audibles, signs, gestures, and picture symbols. Traditionally, Speech-Language Pathologists (SLPs) are the primary facilitators of AAC devices and help establish the language individuals with …

A Comprehensive Review On Medical Diagnosis Using Machine Learning, Kaustubh Arun Bhavsar, Ahed Abugabah, Jimmy Singla, Ahmad Ali Alzubi, Ali Kashif Bashir, Nikita

All Works

The unavailability of sufficient information for proper diagnosis, incomplete or miscommunication between patient and the clinician, or among the healthcare professionals, delay or incorrect diagnosis, the fatigue of clinician, or even the high diagnostic complexity in limited time can lead to diagnostic errors. Diagnostic errors have adverse effects on the treatment of a patient. Unnecessary treatments increase the medical bills and deteriorate the health of a patient. Such diagnostic errors that harm the patient in various ways could be minimized using machine learning. Machine learning algorithms could be used to diagnose various diseases with high accuracy. The use of machine …

Modeling And Analysis Of Covid-19 And Dynamical Systems In Biology And Physics, Vladimir Grbic

Honors Undergraduate Theses

In this paper, we study various examples of dynamical systems found in nature and extract the necessary concepts to build upon. Then, we develop and propose a new deterministic model for COVID-19 propagation. Our model should serve two purposes. First, we will approximate the infected and deceased individuals after a given time during the pandemic. Then, using a linearized subsystem describing infectious compartments about the disease- free equilibrium (DFE), we will determine the basic reproductive number (R0) by the next-generation matrix method.

Solutions For Fermi Questions, March 2021, Larry Weinstein

Physics Faculty Publications

No abstract provided.

Food Contact Surfaces: Challenges, Legislation And Solutions, Shubham Sharma, Amit Jaiswal, Brendan Duffy, Swarna Jaiswal

Articles

Food contact surfaces (FCSs) include all surfaces that may come in contact with the food during production, processing, and packaging. Food processing industries encounter several challenges due to its microbial interaction with the FCSs, such as cross-contamination of pathogenic microorganisms or allergens in food, formation of biofilm, biodeterioration of food contact surface leads to food with reduced shelf-life and quality. A legal EU framework provides the fundamental postulates for the safety and inertness of all Food Contact Materials (FCMs). Legislations have an important role in providing regulatory guidance on the quality assurance systems and verifying their implementation as a means …

Data-Fusion For Epidemiological Analysis Of Covid-19 Variants In Uae, Anoud Bani-Hani, Anaïs Lavorel, Newel Bessadet

All Works

Since December 2019, a new pandemic has appeared causing a considerable negative global impact. The SARS-CoV-2 first emerged from China and transformed to a global pandemic within a short time. The virus was further observed to be spreading rapidly and mutating at a fast pace, with over 5,775 distinct variations of the virus observed globally (at the time of submitting this paper). Extensive research has been ongoing worldwide in order to get a better understanding of its behaviour, influence and more importantly, ways for reducing its impact. Data analytics has been playing a pivotal role in this research to obtain …

Early Detection Of Lung Cancer - A Challenge, Fatma Taher, Neema Prakash, Ashraf Alzaabi

All Works

Lung cancer or lung carcinoma, is a common and serious type of cancer caused by rapid cell growth in tissues of the lung. Lung cancer detection at its earlier stage is very difficult because of the structure of the cell alignment which makes it very challenging. Computed tomography (CT) scan is used to detect the presence of cancer and its spread. Visual analysis of CT scan can lead to late treatment of cancer; therefore, different steps of image processing can be used to solve this issue. A comprehensive framework is used for the classification of pulmonary nodules by combining appearance …

Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence

Theses and Dissertations

Combining vibrating mesh nebulizers with additional new technologies leads to substantial improvements in pharmaceutical aerosol delivery to the lungs across therapeutic administration methods. In this dissertation, streamlined components, aerosol administration synchronization, and/or Excipient Enhanced Growth (EEG) technologies were utilized to develop and test several novel devices and aerosol delivery systems. The first focus of this work was to improve the poor delivery efficiency, e.g., 3.6% of nominal dose (Dugernier et al. 2017), of aerosolized medication administration to adult human subjects concurrent with high flow nasal cannula (HFNC) therapy, a form of continuous-flow non-invasive ventilation (NIV). The developed Low-Volume Mixer-Heater (LVMH) …

Dietary Flexibility Of Wood Storks In Response To Human-Induced Rapid Environmental Change, Betsy A. Evans, Jessica A. Klassen, Dale E. Gawlik

United States Department of Agriculture Wildlife Services: Staff Publications

Human-induced rapid environmental change (HIREC) has altered landscape processes and negatively impacted many species globally. Some of the most dramatic changes have been in wetlands where flows have been disrupted, and new wetlands have been created to retain runoff. In response to disrupted natural wetland conditions, Wood Stork (Mycteria americana) populations in South Florida have significantly declined over the past several decades. Despite the well-documented sensitivity of Wood Storks to natural wetland conditions, Wood Storks are often observed foraging in roadside created wetlands; however, the availability of prey in created wetlands is currently unknown. We sampled natural and created wetlands …

Social Identity And Acceptability Of Wild Pig (Sus Scrofa) Control Actions: A Case Study Of Texas Hunters, Lauren Jaebker, Tara L. Teel, Alan D. Bright, Hailey E. Mclean, John M. Tomeček, Maureen G. Frank, Rachael L. Connally, Stephanie A. Shwiff, Keith M. Carlisle

United States Department of Agriculture Wildlife Services: Staff Publications

Wild pigs (Sus scrofa) pose significant challenges to wildlife managers. This research explored Texas hunters’ acceptability of wild pig control actions, and whether acceptability varied according to hunters’ affiliation with four different categories of natural resource organizations as an indicator of social identity. Results of a survey (n = 37,317) revealed that most hunters were accepting of all control actions except toxicants and non-lethal deterrents. Mean acceptability scores for each action differed significantly across the four affiliation categories, but effect sizes were minimal. Hunters affiliated with agricultural organizations were the most accepting of control actions, while hunters with …

Social Media As A Window Into Human-Wildlife Interactions And Zoonotic Disease Risk: An Examination Of Wild Pig Hunting Videos On Youtube, Hailey E. Mclean, Lauren M. Jaebker, Aaron M. Anderson, Tara L. Teel, Alan D. Bright, Stephanie A. Shwiff, Keith M. Carlisle

United States Department of Agriculture Wildlife Services: Staff Publications

Wild pigs (Sus scrofa) damage agriculture and the environment, as well as transmit diseases to animals and people. Hunters are particularly vulnerable to zoonotic disease risks when harvesting wild pigs. Management agencies have endeavored to inform the public about disease risks associated with wild pigs and best practices for mitigating such risks. However, the extent that this guidance has reached hunters and influenced their practices is unclear. We approached this topic through an analysis of wild pig hunting videos on YouTube. We found evidence of relatively few behaviors and communications regarding disease risks and best practices for personal …

Strategic Considerations For Invasive Species Managers In The Utilization Of Environmental Dna (Edna): Steps For Incorporating This Powerful Surveillance Tool, Jeffrey Morisette, Stanley Burgiel, Kelsey Brantley, Wesley M. Daniel, John Darling, Jeanette Davis, Thomas Franklin, Keith Gaddis, Margaret Hunter, Richard Lance, Tracy Leskey, Yale Passamaneck, Antoinette Piaggio, Brian Rector, Adam Sepulveda, Melissa Smith, Carol A. Stepien, Taylor Wilcox

United States Department of Agriculture Wildlife Services: Staff Publications

Invasive species surveillance programs can utilize environmental DNA sampling and analysis to provide information on the presence of invasive species. Wider utilization of eDNA techniques for invasive species surveillance may be warranted. This paper covers topics directed towards invasive species managers and eDNA practitioners working at the intersection of eDNA techniques and invasive species surveillance. It provides background information on the utility of eDNA for invasive species management and points to various examples of its use across federal and international programs. It provides information on 1) why an invasive species manager should consider using eDNA, 2) deciding if eDNA can …

Reproductive Trade-Offs In The Colorado Checkered Whiptail Lizard (Aspidoscelis Neotesselatus): An Examination Of The Relationship Between Clutch And Follicle Size, Hannah E. Caracalas, S. S. French, S. B. Hudson, B. M. Kluever, A. C. Webb, D. Eifler, A. J. Lehmicke, Lise M. Aubry

United States Department of Agriculture Wildlife Services: Staff Publications

Life history theory predicts that there should be an inverse relationship between offspring size and number, because individuals cannot simultaneously maximize both when resources are limited. Although extensively studied in avian species, the occurrence and determinants of reproductive tradeoffs in oviparous reptiles are far less understood, particularly in parthenogenetic species. We studied this trade-off in the Colorado Checkered Whiptail, Aspidoscelis neotesselatus, a female-only parthenogenetic lizard. Using data previously collected in 2018 and 2019, we tested for clutch and egg size trade-offs and determined whether this relationship could be influenced by female size and aspects of physiological condition. Physiological condition …

Differing Alterations Of Odor Volatiles Among Pathogenic Stimuli, Patrick Millet, Talia Martin, Maryanne Opiekun, Gary K. Beauchamp, Bruce A. Kimball

United States Department of Agriculture Wildlife Services: Staff Publications

Alterations of the volatile metabolome (the collection of volatiles present in secretions and other emanations) that occur in response to inflammation can be detected by conspecifics and chemometric analyses. Using a model system where mouse urinary metabolites are altered by treatment with lipopolysaccharide (found in the outer cell membrane of gram-negative bacteria), we hypothesized that alteration of body odor volatiles will vary according to the pathogen responsible for inducing the inflammation. We tested this hypothesis by treating mice with different immunogens that engage different immune signaling pathways. Results suggest that alterations of body odor volatiles resulting from inflammation do contain …

Influenza A Virus Surveillance, Infection And Antibody Persistence In Snow Geese (Anser Caerulescens), Susan A. Shriner, J. Jeffrey Root, Jeremy W. Ellis, Kevin T. Bentler, Kaci K. Vandalen, Thomas Gidlewski, Sarah N. Bevins

United States Department of Agriculture Wildlife Services: Staff Publications

Some snow geese (Anser caerulescens) migrate between Eurasia and North America and exhibit high seroprevalence for influenza A viruses (IAVs). Hence, these birds might be expected to play a role in intercontinental dispersal of IAVs. Our objective in this manuscript was to characterize basic incidence and infection characteristics for snow geese to assess whether these birds are likely to significantly contribute to circulation of IAVs. Thus, we 1) estimated snow goose infection prevalence by summarizing > 5,000 snow goose surveillance records, 2) experimentally infected snow geese with a low pathogenic IAV (H4N6) to assess susceptibility and infection dynamics and …

Social Structure Defines Spatial Transmission Of African Swine Fever In Wild Boar, Kim M. Pepin, Andrew J. Golnar, Tomasz Podgórski

United States Department of Agriculture Wildlife Services: Staff Publications

The spatial spread of infectious disease is determined by spatial and social processes such as animal space use and family group structure. Yet, the impacts of social processes on spatial spread remain poorly understood and estimates of spatial transmission kernels (STKs) often exclude social structure. Understanding the impacts of social structure on STKs is important for obtaining robust inferences for policy decisions and optimizing response plans. We fit spatially explicit transmission models with different assumptions about contact structure to African swine fever virus surveillance data from eastern Poland from 2014 to 2015 and evaluated how social structure affected inference of …

Scaup Depredation On Arkansas Baitfish And Sportfish Aquaculture, Stephen A. Clements, Brian S. Dorr, J. Brian Davis, Luke A. Roy, Carole R. Engle, Katie C. Hanson-Dorr, Anita M. Kelly

United States Department of Agriculture Wildlife Services: Staff Publications

Lesser scaup (Aythya affinis) and greater scaup (A. marila), hereafter scaup, consume a variety of aquatic invertebrates, plants, and occasionally small fish. Scaup have foraged on commercial aquaculture farms in the southern United States for decades. However, the types, abundance, and rate of fish exploitation by scaup on baitfish and sportfish farms are not well documented. Thus, information is needed to understand how fish and other foods influence scaup use of aquatic resources, and any potential economic effects of depredation of fish. From November–March in winters 2016–2017 and 2017–2018, we conducted 1,458 pond surveys to estimate …

Using Object-Based Image Analysis To Detect Laughing Gull Nests, Benjamin F. Martini, Douglas A. Miller

United States Department of Agriculture Wildlife Services: Staff Publications

Remote sensing has long been used to study wildlife; however, manual methods of detecting wildlife in aerial imagery are often time-consuming and prone to human error, and newer computer vision techniques have not yet been extensively applied to wildlife surveys. We used the object-based image analysis (OBIA) software eCognition to detect laughing gull (Leucophaeus atricilla) nests in Jamaica Bay as part of an ongoing monitoring effort at the John F. Kennedy International Airport. Our technique uses a combination of high resolution 4-band aerial imagery captured via manned aircraft with a multispectral UltraCam Falcon M2 camera, LiDAR point cloud data, and …

Detection Of Two Dissimilar Chronic Wasting Disease Isolates In Two Captive Rocky Mountain Elk (Cervus Canadensis) Herds: Two Distinctive Chronic Wasting Disease Isolates Identified In Captive Elk, Tracy A. Nichols, Eric M. Nicholson, Yihui Liu, Wanyin Tao, Terry R. Spraker, Michael Lavelle, Justin W. Fischer, Qingzhong Kong, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Chronic wasting disease (CWD) continues to spread in both wild and captive cervid herds in North America and has now been identified in wild reindeer and moose in Norway, Finland and Sweden. There is limited knowledge about the variety and characteristics of isolates or strains of CWD that exist in the landscape and their implications on wild and captive cervid herds. In this study, we evaluated brain samples from two captive elk herds that had differing prevalence, history and timelines of CWD incidence. Site 1 had a 16-year history of CWD with a consistently low prevalence between 5% and 10%. …

Spatial Transferability Of Expert Opinion Models For American Beaver Habitat, Isidro Barela, Leslie M. Burger, Guiming Wang, Kristine O. Evans, Qingmin Meng, Jimmy D. Taylor

United States Department of Agriculture Wildlife Services: Staff Publications

Species distribution models and habitat suitability models (HSMs) have become a popular tool in the conservation of biodiversity. However, the ability to predict species spatial distributions at sites beyond the data source sites (i.e., spatial transferability) is critical for the applications of HSMs in the management and conservation of rare or endangered species. The main objective of our study was to assess the predictive performance and spatial transferability of expert opinion models (EOMs). To build EOMs, we identified through extensive literature reviews 17 key landscape variables to characterize habitat use by American beaver (Castor canadensis). We developed 31 pairwise opinion …

Evaluating Potential Effects Of Solar Power Facilities On Wildlife From An Animal Behavior Perspective, Rachel Y. Chock, Barbara Clucas, Elizabeth K. Peterson, Bradley Blackwell, Daniel T. Blumstein, Kathleen Church, Esteban Fernández-Juricic, Gabriel Francescoli, Alison L. Greggor, Paul Kemp, Gabriela M. Pinho, Peter M. Sanzenbacher, Bruce A. Schulte, Pauline Toni

United States Department of Agriculture Wildlife Services: Staff Publications

Solar power is a renewable energy source with great potential to help meet increasing global energy demands and reduce our reliance on fossil fuels. However, research is scarce on how solar facilities affect wildlife. With input from professionals in ecology, conservation, and energy, we conducted a research-prioritization process and identified key questions needed to better understand impacts of solar facilities on wildlife. We focused on animal behavior, which can be used to identify population responses before mortality or other fitness consequences are documented. Behavioral studies can also offer approaches to understand the mechanisms leading to negative interactions (e.g., collision, singeing, …

Food Habits Of Wintering Double-Crested Cormorants In The Mississippi Delta, Terrel W. Christie, Brian S. Dorr, J. Brian Davis, Luke A. Roy, Carole R. Engle, Katie Hanson-Dorr, Anita M. Kelly

United States Department of Agriculture Wildlife Services: Staff Publications

Given its ubiquity, it is not surprising that agriculture, including fin fish aquaculture, contributes to food webs worldwide and is used by numerous wildlife for foraging and meeting other needs. Double-crested Cormorants (Phalacrocorax auritus) impact United States commercial aquaculture and are considered the primary avian predator in catfish (Ictalurus spp.) aquaculture facilities in the Mississippi Delta. Recent changes in aquaculture practices, regulatory policies, and decreased overall hectares in production prompted this study that assessed cormorant consumption of catfish in relation to their night roosts through surveys and diet analysis. Cormorants were collected from night roosts from October …

Principal Economic Effects Of Cormorant Predation On Catfish Farms, Carole R. Engle, Terrel W. Christie, Brian S. Dorr, Ganesh Kumar, Luke A. Roy, Anita M. Kelly

United States Department of Agriculture Wildlife Services: Staff Publications

Substantial economic losses of farmed catfish to fish-eating birds such as the double-crested cormorant, Phalacrocorax auritus, continue to be reported on U.S. catfish farms. An economic analysis was conducted of the on-farm effects of both the increased expenditures to scare fish-eating birds from catfish farms and of the value of the catfish that were consumed by cormorants. A survey was conducted of U.S. catfish farmers in the Delta region of Mississippi and Arkansas, to obtain farm-level data on expenditures to scare birds. Estimations of the lost revenue from catfish consumed by cormorants were developed from a concurrent study on …

Population Genomic Transformations Induced By Isolation Of Wild Bird Avian Influenza Viruses (Orthomyxoviridae) In Embryonated Chicken Eggs, Matthew W. Hopken, Antoinette J. Piaggio, K. L. Pabilonia, James Pierce, Theodore Anderson, Courtney Pierce, Zaid Abdo

United States Department of Agriculture Wildlife Services: Staff Publications

Isolation and cultivation of wild-type viruses in model organism cells or tissues is standard practice in virology. Oftentimes, the virus host species is distantly related to the species from which the culture system was developed. Thus, virus culture in these tissues and cells basically constitutes a host jump, which can lead to genomic changes through genetic drift and/or adaptation to the culture system. We directly sequenced 70 avian influenza virus (Orthomyxoviridae) genomes from oropharyngeal/cloacal swabs collected from wild bird species and paired virus isolates propagated from the same samples following isolation in specific-pathogen-free embryonated chicken eggs. The data were analyzed …

Variation In Angiostrongylus Cantonensis Infection In Definitive And Intermediate Hosts In Hawaii, A Global Hotspot Of Rat Lungworm Disease, Chris Niebuhr, Shane R. Siers, Israel Leinbach, Lisa M. Kaluna, Susan I. Jarvi

United States Department of Agriculture Wildlife Services: Staff Publications

Angiostrongylus cantonensis (rat lungworm) is a tropical and subtropical parasitic nematode, with infections in humans causing angiostrongyliasis (rat lungworm disease), characterized by eosinophilic meningitis. Hawaii has been identified as a global hotspot of infection, with recent reports of high infection rates in humans, as well as rat definitive and snail intermediate hosts. This study investigated variation in A. cantonensis infection, both prevalence and intensity, in wild populations of two species of rats (Rattus exulans and R. rattus) and one species of snail (Parmarion martensi). An overall infection prevalence of 86.2% was observed in P. martensi and …

Estimation Of Wildlife Damage From Federal Crop Insurance Data, Sophie Mckee, Stephanie A. Shwiff, Aaron M. Anderson

United States Department of Agriculture Wildlife Services: Staff Publications

BACKGROUND: Wildlife damage to crops is a persistent and costly problem for many farmers in the USA. Most existing estimates of crop damage have relied on direct assessment methods such as field studies conducted by trained biologists or surveys distributed to farmers. In this paper, we describe a new method of estimating wildlife damage that exploits federal crop insurance data. We focused our study on four crops: corn, soybean, wheat, and cotton, chosen because of their economic importance and their vulnerability to wildlife damage.

RESULTS: We determined crop-raiding hot spots across the USA over the 2015–2019 period and identified the …

Avian Use Of Exotic Street Treescapes In Metropolitan Areas Of Phoenix, Arizona, Brian E. Washburn, Karen Hoss, David L. Bergman

United States Department of Agriculture Wildlife Services: Staff Publications

Urban areas are highly modified environments that are strongly influenced by a variety of anthropogenic factors. Consequently, these areas contain unique wildlife communities typically dominated by species that are generalist in nature or highly adaptable. We examined the use of five species of exotic treescapes by exotic and native birds in metropolitan areas of Phoenix, Arizona. House Sparrows [Passer domesticus (37%)], European Starlings [Sturnus vulagris (27%)], Mourning Doves [Zenaida macroura (11%)], and Great-tailed Grackles [Quiscalus mexicanus (7%)] were the most frequently observed species during the study. Approximately two-thirds (67%) of the birds observed during the study were exotic species. Avian …

Anthraquinone Repellent Seed Treatment On Corn Reduces Feeding By Wild Pigs, Nathan P. Snow, Joseph M. Halseth, Scott J. Werner, Kurt C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Wild pigs (Sus scrofa) are a destructive invasive species that cause extensive damage to agriculture throughout many regions of the world. In particular wild pigs damage corn more than any other crop, and most of that damage occurs immediately after planting when wild pigs excavate and consume planted seeds. We evaluated whether anthraquinone (AQ), a repellent, could be useful for protecting seed corn from consumption by wild pigs. Specifically, we conducted cafeteria-style tests at 16 bait sites for 6 nights using concentrations of: untreated, 0.5, 1.5, and 3.0% AQ by weight sprayed on whole-kernel corn in AL and …

The Evolutionary Consequences Of Human–Wildlife Conflict In Cities, Christopher J. Schell, Lauren Stanton, Julie K. Young, Lisa Angeloni, Joanna E. Lambert, Stewart W. Breck, Maureen H. Murray

United States Department of Agriculture Wildlife Services: Staff Publications

Human–wildlife interactions, including human–wildlife conflict, are increasingly common as expanding urbanization worldwide creates more opportunities for people to encounter wildlife. Wildlife–vehicle collisions, zoonotic disease transmission, property damage, and physical attacks to people or their pets have negative consequences for both people and wildlife, underscoring the need for comprehensive strategies that mitigate and prevent conflict altogether. Management techniques often aim to deter, relocate, or remove individual organisms, all of which may present a significant selective force in both urban and nonurban systems. Managementinduced selection may significantly affect the adaptive or nonadaptive evolutionary processes of urban populations, yet few studies explicate the …