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Articles 3031 - 3060 of 11885

Full-Text Articles in Physical Sciences and Mathematics

Nicotine In Tobacco Product Aerosols: 'It's Deja Vu All Over Again', Anna K. Duell, James F. Pankow, David H. Peyton Nov 2020

Nicotine In Tobacco Product Aerosols: 'It's Deja Vu All Over Again', Anna K. Duell, James F. Pankow, David H. Peyton

Chemistry Faculty Publications and Presentations

Introduction: The distribution of nicotine among its free-base (fb) and protonated forms in aerosolised nicotine affects inhalability. It has been manipulated in tobacco smoke and now in electronic cigarettes by the use of acids to de-freebase nicotine and form ‘nicotine salts’.

Methods: Measurements on electronic cigarette fluids (e-liquids) were carried out to determine (1) the fraction of nicotine in the free-base form (α fb) and (2) the levels of organic acid(s) and nicotine. Samples included JUUL ‘pods’, ‘look-a-like/knock-off’ pods and some bottled ‘nicotine salt’ and ‘non-salt’ e-liquids.

Results: α fb= 0.12 ±0.01 at 40°C (≈ 37°C) for 10 JUUL products, …


A Statistical Learning Regression Model Utilized To Determine Predictive Factors Of Social Distancing During Covid-19 Pandemic, Timothy A. Smith, Albert J. Boquet, Matthew V. Chin Nov 2020

A Statistical Learning Regression Model Utilized To Determine Predictive Factors Of Social Distancing During Covid-19 Pandemic, Timothy A. Smith, Albert J. Boquet, Matthew V. Chin

Publications

In an application of the mathematical theory of statistics, predictive regression modelling can be used to determine if there is a trend to predict the response variable of social distancing in terms of multiple predictor input “predictor” variables. In this study the social distancing is measured as the percentage reduction in average mobility by GPS records, and the mathematical results obtained are interpreted to determine what factors drive that response. This study was done on county level data from the state of Florida during the COVID-19 pandemic, and it is found that the most deterministic predictors are county population density …


Spotted Owls And Forest Fire: Comment, Gavin M. Jones, R. J. Gutiérrez, William M. Block, Peter C. Carlson, Emily J. Comfort, Samuel A. Cushman, Raymond J. Davis, Stephanie A. Eyes, Alan B. Franklin, Joseph L. Ganey, Shaula Hedwall, John J. Keane, Rodd Kelsey, Damon B, Lesmeister, Malcolm P. North, Susan L. Roberts, Jeremy T. Rockweit, Jamie S. Sanderlin, Sarah C. Sawyer, Ben Solvesky, Douglas J. Tempel, Ho Yi Wan, A. Leroy Westerling, Gary C. White, M. Zachariah Peery Nov 2020

Spotted Owls And Forest Fire: Comment, Gavin M. Jones, R. J. Gutiérrez, William M. Block, Peter C. Carlson, Emily J. Comfort, Samuel A. Cushman, Raymond J. Davis, Stephanie A. Eyes, Alan B. Franklin, Joseph L. Ganey, Shaula Hedwall, John J. Keane, Rodd Kelsey, Damon B, Lesmeister, Malcolm P. North, Susan L. Roberts, Jeremy T. Rockweit, Jamie S. Sanderlin, Sarah C. Sawyer, Ben Solvesky, Douglas J. Tempel, Ho Yi Wan, A. Leroy Westerling, Gary C. White, M. Zachariah Peery

United States Department of Agriculture Wildlife Services: Staff Publications

Western North American forest ecosystems are experiencing rapid changes in disturbance regimes because of climate change and land use legacies (Littell et al. 2018). In many of these forests, the accumulation of surface and ladder fuels from a century of fire suppression, coupled with a warming and drying climate, has led to increases in the number of large fires (Westerling 2016) and the proportion of areas burning at higher severity (Safford and Stevens 2017, Singleton et al. 2018). While the annual area burned by fire is still below historical levels (Taylor et al. 2016), some forest types in the west …


9th International Conference On Business, Technology And Innovation 2020, University For Business And Technology - Ubt Oct 2020

9th International Conference On Business, Technology And Innovation 2020, University For Business And Technology - Ubt

UBT International Conference

Welcome to IC – UBT 2020

UBT Annual International Conference is the 9th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make …


Multi-Ancestry Genome-Wide Association Study Accounting For Gene-Psychosocial Factor Interactions Identifies Novel Loci For Blood Pressure Traits, Daokun Sun, Melissa A. Richard, Soloman K. Musani, Yun Ju Sung, Thomas W. Winkler, Karen Schwander, Jin Fang Chai, Xiuqing Guo, Tuomas O. Kilpeläinen, Dina Vojinovic, Hugues Aschard, Traci M. Bartz, Lawrence F. Bielak, Michael R. Brown, Kumaraswamy Chitrala, Fernando P. Hartwig, Andrea R. V. R. Horimoto, Yongmei Liu, Alisa K. Manning, Raymond Noordam, Donna K. Arnett Oct 2020

Multi-Ancestry Genome-Wide Association Study Accounting For Gene-Psychosocial Factor Interactions Identifies Novel Loci For Blood Pressure Traits, Daokun Sun, Melissa A. Richard, Soloman K. Musani, Yun Ju Sung, Thomas W. Winkler, Karen Schwander, Jin Fang Chai, Xiuqing Guo, Tuomas O. Kilpeläinen, Dina Vojinovic, Hugues Aschard, Traci M. Bartz, Lawrence F. Bielak, Michael R. Brown, Kumaraswamy Chitrala, Fernando P. Hartwig, Andrea R. V. R. Horimoto, Yongmei Liu, Alisa K. Manning, Raymond Noordam, Donna K. Arnett

Epidemiology and Environmental Health Faculty Publications

Psychological and social factors are known to influence blood pressure (BP) and risk of hypertension and associated cardiovascular diseases. To identify novel BP loci, we carried out genome-wide association meta-analyses of systolic, diastolic, pulse, and mean arterial BP, taking into account the interaction effects of genetic variants with three psychosocial factors: depressive symptoms, anxiety symptoms, and social support. Analyses were performed using a two-stage design in a sample of up to 128,894 adults from five ancestry groups. In the combined meta-analyses of stages 1 and 2, we identified 59 loci (p value < 5e−8), including nine novel BP loci. The novel associations were observed mostly with pulse pressure, with fewer observed with mean arterial pressure. Five novel loci were identified in African ancestry, and all but one showed patterns of interaction with at least one psychosocial factor. Functional annotation of the novel loci supports a major role for genes implicated in the immune response (PLCL2), synaptic function and neurotransmission (LIN7A …


The Use Of Penalized Regression Analysis To Identify County-Level Demographic And Socioeconomic Variables Predictive Of Increased Covid-19 Cumulative Case Rates In The State Of Georgia, Holly L. Richmond, Joana Tome, Haresh Rochani, Isaac Chun-Hai Fung, Gulzar H. Shah, Jessica S. Schwind Oct 2020

The Use Of Penalized Regression Analysis To Identify County-Level Demographic And Socioeconomic Variables Predictive Of Increased Covid-19 Cumulative Case Rates In The State Of Georgia, Holly L. Richmond, Joana Tome, Haresh Rochani, Isaac Chun-Hai Fung, Gulzar H. Shah, Jessica S. Schwind

Department of Biostatistics, Epidemiology, and Environmental Health Sciences Faculty Publications

Systemic inequity concerning the social determinants of health has been known to affect morbidity and mortality for decades. Significant attention has focused on the individual-level demographic and co-morbid factors associated with rates and mortality of COVID-19. However, less attention has been given to the county-level social determinants of health that are the main drivers of health inequities. To identify the degree to which social determinants of health predict COVID-19 cumulative case rates at the county-level in Georgia, we performed a sequential, cross-sectional ecologic analysis using a diverse set of socioeconomic and demographic variables. Lasso regression was used to identify variables …


A Hybrid Agent-Based And Equation Based Model For The Spread Of Infectious Diseases, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher Oct 2020

A Hybrid Agent-Based And Equation Based Model For The Spread Of Infectious Diseases, Elizabeth Hunter, Brian Mac Namee, John D. Kelleher

Articles

Both agent-based models and equation-based models can be used to model the spread of an infectious disease. Equation-based models have been shown to capture the overall dynamics of a disease outbreak while agent-based models are able to capture heterogeneous characteristics of agents that drive the spread of an outbreak. However, agent-based models are computationally intensive. To capture the advantages of both the equation-based and agent-based models, we create a hybrid model where the disease component of the hybrid model switches between agent-based and equation-based. The switch is determined using the number of agents infected. We first test the model at …


A New Efficient Method To Detect Genetic Interactions For Lung Cancer Gwas, Jennifer Luyapan, Xuemei Ji, Siting Li, Xiangjun Xiao, Dakai Zhu, Eric J. Duell, David C. Christiani, Matthew B. Schabath, Susanne M. Arnold, Shanbeh Zienolddiny, Hans Brunnström, Olle Melander, Mark D. Thornquist, Todd A. Mackenzie, Christopher I. Amos, Jiang Gui Oct 2020

A New Efficient Method To Detect Genetic Interactions For Lung Cancer Gwas, Jennifer Luyapan, Xuemei Ji, Siting Li, Xiangjun Xiao, Dakai Zhu, Eric J. Duell, David C. Christiani, Matthew B. Schabath, Susanne M. Arnold, Shanbeh Zienolddiny, Hans Brunnström, Olle Melander, Mark D. Thornquist, Todd A. Mackenzie, Christopher I. Amos, Jiang Gui

Markey Cancer Center Faculty Publications

BACKGROUND: Genome-wide association studies (GWAS) have proven successful in predicting genetic risk of disease using single-locus models; however, identifying single nucleotide polymorphism (SNP) interactions at the genome-wide scale is limited due to computational and statistical challenges. We addressed the computational burden encountered when detecting SNP interactions for survival analysis, such as age of disease-onset. To confront this problem, we developed a novel algorithm, called the Efficient Survival Multifactor Dimensionality Reduction (ES-MDR) method, which used Martingale Residuals as the outcome parameter to estimate survival outcomes, and implemented the Quantitative Multifactor Dimensionality Reduction method to identify significant interactions associated with age of …


S3e7: Did Climate Impact Wwi, Spanish Flu Casualties?, Ron Lisnet, Paul A. Mayewski, Alex More Oct 2020

S3e7: Did Climate Impact Wwi, Spanish Flu Casualties?, Ron Lisnet, Paul A. Mayewski, Alex More

The Maine Question

Incessant torrential rain and cold air over Europe from 1914 to 1919 likely increased the number of people who died during World War I (22 million) and the Spanish flu pandemic (50 million). Alex More and Paul Mayewski from the Climate Change Institute connected data from climate science, history and public health to make the discovery. The colleagues say the once-in-a-century climate anomaly may have been caused by dust and explosives from the war that impacted the local atmosphere. As we anticipate another wave of COVID-19, More says we should be mindful of the interconnectedness of human-caused climate change, environmental …


Combating Acquired Resistance To Mapk Inhibitors In Melanoma By Targeting Abl1/2-Mediated Reactivation Of Mek/Erk/Myc Signaling, Rakshamani Tripathi, Zulong Liu, Aditi Jain, Anastasia Lyon, Christina Meeks, Dana Richards, Jinpeng Liu, Daheng He, Chi Wang, Marika Nespi, Andrey Rymar, Peng Wang, Melissa Wilson, Rina Plattner Oct 2020

Combating Acquired Resistance To Mapk Inhibitors In Melanoma By Targeting Abl1/2-Mediated Reactivation Of Mek/Erk/Myc Signaling, Rakshamani Tripathi, Zulong Liu, Aditi Jain, Anastasia Lyon, Christina Meeks, Dana Richards, Jinpeng Liu, Daheng He, Chi Wang, Marika Nespi, Andrey Rymar, Peng Wang, Melissa Wilson, Rina Plattner

Pharmacology and Nutritional Sciences Faculty Publications

Metastatic melanoma remains an incurable disease for many patients due to the limited success of targeted and immunotherapies. BRAF and MEK inhibitors reduce metastatic burden for patients with melanomas harboring BRAF mutations; however, most eventually relapse due to acquired resistance. Here, we demonstrate that ABL1/2 kinase activities and/or expression are potentiated in cell lines and patient samples following resistance, and ABL1/2 drive BRAF and BRAF/MEK inhibitor resistance by inducing reactivation of MEK/ERK/MYC signaling. Silencing/inhibiting ABL1/2 blocks pathway reactivation, and resensitizes resistant cells to BRAF/MEK inhibitors, whereas expression of constitutively active ABL1/2 is sufficient to promote resistance. Significantly, nilotinib (2nd generation …


Global Air Quality Trekkers: Nandi Clean Kitchen Study, Samantha Dykhuis, Stephanie Schiavo, Avalin Senefeld Oct 2020

Global Air Quality Trekkers: Nandi Clean Kitchen Study, Samantha Dykhuis, Stephanie Schiavo, Avalin Senefeld

Purdue Journal of Service-Learning and International Engagement

Indoor air pollution is a widespread environmental health challenge sub-Saharan Africa and is the leading cause of premature death in many sub-Saharan African countries. This pollution is primarily caused by the burning of biomass fuels inside an enclosed kitchen in order to provide heat for cooking. Global Air Quality Trekkers is an undergraduate engineering team within the EPICS department at Purdue that began in fall 2016. Our objective is to create a kitchen design that utilizes natural ventilation to mitigate the amount of air pollutants present in these kitchens, specifically in the Nandi community of Western Kenya. This year, our …


Association Between Dietary Inflammatory Index And Type 2 Diabetes Mellitus In Xinjiang Uyghur Autonomous Region, China, Wenhui Fu, Hualian Pei, Nitin Shivaooa, James R. Hébert, Tao Luo, Tian Tian, Dilibaier Alimu, Zewen Zhang, Jianghong Dai Oct 2020

Association Between Dietary Inflammatory Index And Type 2 Diabetes Mellitus In Xinjiang Uyghur Autonomous Region, China, Wenhui Fu, Hualian Pei, Nitin Shivaooa, James R. Hébert, Tao Luo, Tian Tian, Dilibaier Alimu, Zewen Zhang, Jianghong Dai

Faculty Publications

Background Diet and inflammation have both been studied in relation to type 2 diabetes mellitus (T2DM). The aim of this cross-sectional study was to examine the association between the Dietary Inflammatory Index (DII®) and T2DM. Methods Subjects were adults enrolled in the baseline study of the Xinjiang multi-ethnic natural population cohort and health follow-up study from January to May 2019. The study involved 5,105 subjects (58.7% men) between 35 and 74 years of age. The DII score was calculated from a data obtained via a food frequency questionnaire consisting of 127 food items. Results Logistic regression analyses were used to …


Loci Associated With Antibody Response In Feral Swine (Sus Scrofa) Infected With Brucella Suis, Courtney F. Pierce, Vienna R. Brown, Steven C. Olsen, Paola Boggiatto, Kerri Pedersen, Ryan S. Miller, Scott E. Speidel, Timothy J. Smyser Oct 2020

Loci Associated With Antibody Response In Feral Swine (Sus Scrofa) Infected With Brucella Suis, Courtney F. Pierce, Vienna R. Brown, Steven C. Olsen, Paola Boggiatto, Kerri Pedersen, Ryan S. Miller, Scott E. Speidel, Timothy J. Smyser

United States Department of Agriculture Wildlife Services: Staff Publications

Feral swine (Sus scrofa) are a destructive invasive species widespread throughout the United States that disrupt ecosystems, damage crops, and carry pathogens of concern for the health of domestic stock and humans including Brucella suis—the causative organism for swine brucellosis. In domestic swine, brucellosis results in reproductive failure due to abortions and infertility. Contact with infected feral swine poses spillover risks to domestic pigs as well as humans, companion animals, wildlife, and other livestock. Genetic factors influence the outcome of infectious diseases; therefore, genome wide association studies (GWAS) of differential immune responses among feral swine can provide …


Covid-19 And Quantitative Literacy: Focusing On Probability, Michael A. Lewis Oct 2020

Covid-19 And Quantitative Literacy: Focusing On Probability, Michael A. Lewis

Numeracy

The COVID-19 pandemic is arguably the worst crisis the world has faced, so far, in this new century. We haven’t seen a pandemic like this since the 1918 Flu at the beginning of the last century, and, as of this writing, there appears to be no end in sight. What those of us who’re focused on quantitative methods have noticed, in addition to the many people dying, becoming ill, and losing their livelihoods, is the importance of quantitative literacy to an understanding of what’s going on. That’s what this article is about. Specifically, it’s about how the COVID-19 pandemic is …


A Review Of Avian Influenza A Virus Associations In Synanthropic Birds, Susan A. Shriner, J. Jeffrey Root Oct 2020

A Review Of Avian Influenza A Virus Associations In Synanthropic Birds, Susan A. Shriner, J. Jeffrey Root

United States Department of Agriculture Wildlife Services: Staff Publications

Avian influenza A viruses (IAV) have received significant attention due to the threat they pose to human, livestock, and wildlife health. In this review, we focus on what is known about IAV dynamics in less common avian species that may play a role in trafficking IAVs to poultry operations. Specifically, we focus on synanthropic bird species. Synanthropic species, otherwise known as peridomestic, are species that are ecologically associated with humans and anthropogenically modified landscapes, such as agricultural and urban areas. Aquatic birds such as waterfowl and shorebirds are the species most commonly associated with avian IAVs, and are generally considered …


Synthesis, In Vitro, And In Vivo Evaluation Of Novel N-Phenylindazolyl Diarylureas As Potential Anti-Cancer Agents., Lucas N Solano, Grady L Nelson, Conor T Ronayne, Shirisha Jonnalagadda, Sravan K Jonnalagadda, Kaija Kottke, Robert Chitren, Joseph L Johnson, Manoj K Pandey, Subash C. Jonnalagadda, Venkatram R Mereddy Oct 2020

Synthesis, In Vitro, And In Vivo Evaluation Of Novel N-Phenylindazolyl Diarylureas As Potential Anti-Cancer Agents., Lucas N Solano, Grady L Nelson, Conor T Ronayne, Shirisha Jonnalagadda, Sravan K Jonnalagadda, Kaija Kottke, Robert Chitren, Joseph L Johnson, Manoj K Pandey, Subash C. Jonnalagadda, Venkatram R Mereddy

College of Science & Mathematics Departmental Research

Novel N-phenylindazole based diarylureas have been designed, synthesized and evaluated as potential anticancer agents. In vitro cell viability studies of these derivatives illustrate good potency with IC50 values in the range of 0.4–50 μM in several cancer cell lines including murine metastatic breast cancer 4T1, murine glioblastoma GL261, human triple negative breast cancer MDA-MB-231, human pancreatic cancer MIAPaCa-2, and human colorectal cancer cell line WiDr. The ester group in the lead compound 8i was modified to incorporate amino-amides to increase solubility and stability while retaining biological activity. Further in vitro studies reveal that lead candidates inhibit tube length in HUVEC …


Sure 2020 Undergraduate Science Conference Booklet, Sure Network Oct 2020

Sure 2020 Undergraduate Science Conference Booklet, Sure Network

Group Reports

The SURE 2020 Conference was the third series of Science Undergraduate Research Experience (SURE) Conferences, following earlier series in 2018 (with three conferences in Dublin, Athlone and Waterford) and in 2019 (with three conferences in Dublin, Sligo and Carlow). The 2020 online conference had a total of 24 oral presentations and 35 poster presentations, and was attended by over 450 students, academic staff, professional body and industry representatives.

The aims of the conference were to:

  1. Provide current students with an opportunity to gain an understanding of the work which has been undertaken by recent graduates, and the career opportunities that …


Mobilizing Crop Biodiversity, Susan Mccouch, Zahra Katy Navabi, Michael Abberton, Noelle L. Anglin, Rosa Lia Barbieri, Michael Baum, Kirstin Bett, Helen Booker, Gerald L. Brown, Glenn J. Bryan, Luigi Cattivelli, David Charest, Kellye Eversole, Marcelo Freitas, Kioumars Ghamkhar, Dario Grattipaglia, Robert Henry, Maria Cleria Valadares Inglis, Tofazzal Islam, Zakaria Kehel, Paul J. Kersey, Graham J. King, Stephen Kresovich, Emily Marden, Sean Mayes, Marie Noelle Ndjiondjiop, Henry T. Nguyen, Samuel Rezende Paiva, Roberto Papa, Peter W.B. Phillips, Awais Rasheed Oct 2020

Mobilizing Crop Biodiversity, Susan Mccouch, Zahra Katy Navabi, Michael Abberton, Noelle L. Anglin, Rosa Lia Barbieri, Michael Baum, Kirstin Bett, Helen Booker, Gerald L. Brown, Glenn J. Bryan, Luigi Cattivelli, David Charest, Kellye Eversole, Marcelo Freitas, Kioumars Ghamkhar, Dario Grattipaglia, Robert Henry, Maria Cleria Valadares Inglis, Tofazzal Islam, Zakaria Kehel, Paul J. Kersey, Graham J. King, Stephen Kresovich, Emily Marden, Sean Mayes, Marie Noelle Ndjiondjiop, Henry T. Nguyen, Samuel Rezende Paiva, Roberto Papa, Peter W.B. Phillips, Awais Rasheed

College of Agriculture and Life Sciences Faculty Publications

No abstract provided.


Modeling The Influence Of Public Risk Perceptions On The Adoption Of Green Stormwater Infrastructure: An Application Of Bayesian Belief Networks Versus Logistic Regressions On A Statewide Survey Of Households In Vermont, Qing Ren, Asim Zia, Donna M. Rizzo, Nancy Mathews Oct 2020

Modeling The Influence Of Public Risk Perceptions On The Adoption Of Green Stormwater Infrastructure: An Application Of Bayesian Belief Networks Versus Logistic Regressions On A Statewide Survey Of Households In Vermont, Qing Ren, Asim Zia, Donna M. Rizzo, Nancy Mathews

College of Engineering and Mathematical Sciences Faculty Publications

There is growing environmental psychology and behavior literature with mixed empirical evidence about the influence of public risk perceptions on the adoption of environmentally friendly “green behaviors”. Adoption of stormwater green infrastructure on residential properties, while costlier in the short term compared to conventional greywater infrastructure, plays an important role in the reduction of nutrient loading from non-point sources into freshwater rivers and lakes. In this study, we use Bayesian Belief Networks (BBNs) to analyze a 2015 survey dataset (sample size = 472 respondents) about the adoption of green infrastructure (GSI) in Vermont’s residential areas, most of which are located …


Santa Clara Magazine, Volume 61 Number 3, Fall 2020 [Print Issue V.61:2], Santa Clara University Oct 2020

Santa Clara Magazine, Volume 61 Number 3, Fall 2020 [Print Issue V.61:2], Santa Clara University

Santa Clara Magazine

16 - THE GIFT Is sacrifice, given willingly and with love, what makes us human? Leslie Griffy.

20 - NOT A MOMENT, BUT A MOVEMENT From protests in Benson in 1969 to a multi-decade movement called Unity, students of color have consistently pushed SCU to progress. Matt Morgan.

28 - ON BEING BETTER Discover the ways we can better support each other, particularly as white people seek to become allies to people of color. Lauren Loftus.

32 - THE SACRIFICIAL TWEET Social media missteps are costly, perhaps now more than ever. Just what are we willing to give up to …


Imaging Data On Characterization Of Retinal Autofluorescent Lesions In A Mouse Model Of Juvenile Neuronal Ceroid Lipofuscinosis (Cln3 Disease), Qing Jun Wang, Kyung Sik Jung, Kabhilan Mohan, Mark E. Kleinman Oct 2020

Imaging Data On Characterization Of Retinal Autofluorescent Lesions In A Mouse Model Of Juvenile Neuronal Ceroid Lipofuscinosis (Cln3 Disease), Qing Jun Wang, Kyung Sik Jung, Kabhilan Mohan, Mark E. Kleinman

Ophthalmology and Visual Science Faculty Publications

Juvenile neuronal ceroid lipofuscinosis (JNCL, aka. juvenile Batten disease or CLN3 disease), a lethal pediatric neurodegenerative disease without cure, often presents with vision impairment and characteristic ophthalmoscopic features including focal areas of hyper-autofluorescence. In the associated research article “Loss of CLN3, the gene mutated in juvenile neuronal ceroid lipofuscinosis, leads to metabolic impairment and autophagy induction in retinal pigment epithelium” (Zhong et al., 2020) [1], we reported ophthalmoscopic observations of focal autofluorescent lesions or puncta in the Cln3Δex7/8 mouse retina at as young as 8 month old. In this data article, we performed differential interference contrast and …


Genome-Wide Association Study In Accessions Of The Mini-Core Collection Of Mungbean (Vigna Radiata) From The World Vegetable Gene Bank (Taiwan), Alena Sokolkova, Marina Burlyaeva, Tatjana Valiannikova, Margarita Vishnyakova, Roland Schafleitner, Cheng Ruei Lee, Chau Ti Ting, Ramakrishnan Madhavan Nair, Sergey Nuzhdin, Maria Samsonova, Eric Von Wettberg Oct 2020

Genome-Wide Association Study In Accessions Of The Mini-Core Collection Of Mungbean (Vigna Radiata) From The World Vegetable Gene Bank (Taiwan), Alena Sokolkova, Marina Burlyaeva, Tatjana Valiannikova, Margarita Vishnyakova, Roland Schafleitner, Cheng Ruei Lee, Chau Ti Ting, Ramakrishnan Madhavan Nair, Sergey Nuzhdin, Maria Samsonova, Eric Von Wettberg

College of Agriculture and Life Sciences Faculty Publications

Background: Mungbean (Vigna radiata (L.) R. Wilczek, or green gram) is important tropical and sub-tropical legume and a rich source of dietary protein and micronutrients. In this study we employ GWAS to examine the genetic basis of variation in several important traits in mungbean, using the mini-core collection established by the World Vegetable Center, which includes 296 accessions that represent the major market classes. This collection has been grown in a common field plot in southern European part of Russia in 2018. Results: We used 5041 SNPs in 293 accessions that passed strict filtering for genetic diversity, linkage disequilibrium, population …


Gym Usage Behavior & Desired Digital Interventions: An Empirical Study, Meeralakshmi Radhakrishnan, Archan Misra, Rajesh Krishna Balan, Youngki Lee Oct 2020

Gym Usage Behavior & Desired Digital Interventions: An Empirical Study, Meeralakshmi Radhakrishnan, Archan Misra, Rajesh Krishna Balan, Youngki Lee

Research Collection School Of Computing and Information Systems

Understanding individual’s exercise motives, participation patterns in a gym and reasons for dropout are essential for designing strategies to help gym-goers with long-term exercise adherence. In this work, we derive insights on various exercise-related behaviors of gymgoers, including evidence of a significant number of individuals exhibiting early dropout and also describing their attitudes towards digital technologies for sustained gym participation. By utilizing gym visitation data logs of 6513 individuals over a longitudinal period of 16 months in a campus gym, we show the retention and dropout rates of gym-goers. Our data indicates that 32% of the people quit their gym …


Dynamical Climatic Model For Time To Flowering In Vigna Radiata, Konstantin Kozlov, Alena Sokolkova, Cheng Ruei Lee, Chau Ti Ting, Roland Schafleitner, Eric Bishop-Von Wettberg, Sergey Nuzhdin, Maria Samsonova Oct 2020

Dynamical Climatic Model For Time To Flowering In Vigna Radiata, Konstantin Kozlov, Alena Sokolkova, Cheng Ruei Lee, Chau Ti Ting, Roland Schafleitner, Eric Bishop-Von Wettberg, Sergey Nuzhdin, Maria Samsonova

College of Agriculture and Life Sciences Faculty Publications

Background: Phenology data collected recently for about 300 accessions of Vigna radiata (mungbean) is an invaluable resource for investigation of impacts of climatic factors on plant development. Results: We developed a new mathematical model that describes the dynamic control of time to flowering by daily values of maximal and minimal temperature, precipitation, day length and solar radiation. We obtained model parameters by adaptation to the available experimental data. The models were validated by cross-validation and used to demonstrate that the phenology of adaptive traits, like flowering time, is strongly predicted not only by local environmental factors but also by plant …


Modeling Alternative Collaborative Governance Network Designs: An Agent-Based Model Of Water Governance In The Lake Champlain Basin, Vermont, Patrick Bitterman, Christopher J. Koliba Oct 2020

Modeling Alternative Collaborative Governance Network Designs: An Agent-Based Model Of Water Governance In The Lake Champlain Basin, Vermont, Patrick Bitterman, Christopher J. Koliba

College of Agriculture and Life Sciences Faculty Publications

Published by Oxford University Press on behalf of the Public Management Research Association. With the widespread use of collaborative governance mechanisms for mitigating water pollution, an opportunity exists to test alternative institutional designs based on collaborative governance theory using computer simulation models, particularly when there is a clear relationship between governance networks, observable resource allocation decisions, and measurable outcomes. This is especially the case for wicked problems like nonpoint source water pollution where there are compelling questions regarding how best to design policies, allocate funds, and build administrative capacity to meet water quality standards. We present an agent-based model (ABM) …


2020 Celebration Of Scholarship, Creativity, And Engagement, Todd Bruns, Beth Heldebrandt Oct 2020

2020 Celebration Of Scholarship, Creativity, And Engagement, Todd Bruns, Beth Heldebrandt

Programs

The 2020-2021 academic year is truly extraordinary and higher education’s new, hopefully temporary, normal began on rather short notice in Spring 2020. While our environment has changed, we, as a shared community, are pleased that the important work of faculty continues and evolves as faculty broaden and redefine the boundaries of scholarship, creativity, and innovation in accelerating hybrid and remote environments. And, as new forms and strategies for scholarship and creativity emerge, the core principles of faculty life and student learning remain central to the mission of Eastern Illinois University.

For that reason, our faculty, department chairs, college deans, the …


Instability Of Glucocorticoid Metabolites In Coyote Scats: Implications For Field Sampling, Erika T. Stevenson, Eric M. Gese, Lorin A. Neuman-Lee, Susannah S. French Oct 2020

Instability Of Glucocorticoid Metabolites In Coyote Scats: Implications For Field Sampling, Erika T. Stevenson, Eric M. Gese, Lorin A. Neuman-Lee, Susannah S. French

United States Department of Agriculture Wildlife Services: Staff Publications

Studying physiologic stress responses can assist in understanding the welfare of animals. One method of measuring the physiologic stress response is evaluating concentrations of glucocorticoid metabolites in feces. Previously, using an adrenocorticotropic hormone challenge, we found fecal glucocorticoid metabolite levels were a reliable indicator of physiologic stress response in coyotes (Canis latrans). We determine whether glucocorticoid metabolite concentrations remain stable when collecting feces over a 2-week period, a timeframe commonly used in scat surveys for wild canids. We collected feces from 6 captive coyotes maintained at the U.S. Department of Agriculture, Wildlife Services, National Wildlife Research Center, Predator …


Mapping Disparities In Covid-19: Determining The Demographic, Economic, Educational, Housing, Quality Of Life, And Health Factors That Relate To Disparities In Covid-19 Infections And Deaths, Kate Stanley, Naima Shifa Oct 2020

Mapping Disparities In Covid-19: Determining The Demographic, Economic, Educational, Housing, Quality Of Life, And Health Factors That Relate To Disparities In Covid-19 Infections And Deaths, Kate Stanley, Naima Shifa

Annual Student Research Poster Session

Background: Throughout the pandemic, minority groups, particularly African Americans and Hispanic/Latino Americans have experienced disproportionately high infection and death rates as compared to their white and Asian counterparts. Though this phenomenon could be attributed to high rates of pre-existing conditions in black and Hispanic communities, there are other underlying factors that cause such disparity. We set out to determine whether or not various demographic, economic, educational, health, housing, and quality of life indicators were correlated with higher rates of COVID-19 infection.

Methods: We used USAFacts COVID-19 data to select the 150 United States counties with the highest infection rates. We …


Tools, Techniques And Teamwork: Transferring New Technologies For Wildlife Management, Conservation And Economic Development, John Eisemann, Gail Keirn Oct 2020

Tools, Techniques And Teamwork: Transferring New Technologies For Wildlife Management, Conservation And Economic Development, John Eisemann, Gail Keirn

United States Department of Agriculture Wildlife Services: Staff Publications

Did you ever wonder who invented radio telemetry? Or breakaway snares? What about the bird repellent methyl anthranilate or the livestock protection collar? These and many other tools used in wildlife damage management resulted from creative thinking by biologists, technicians, researchers and managers working to solve complex wildlife issues. Over the past 90 years, these “aha moments” within the U.S. Department of Agriculture’s Wildlife Services program have ranged from developing novel scare devices, traps and vaccines to exploiting an animal’s visual capabilities to stop unwanted behaviors. Once discovered, these unique ideas may lead to practical, feasible and cost-effective wildlife damage …


Pattern Of Health Behavior And Its Association With Self-Rated Health: Evidence From The 2018 Behavioral Risk Factor Surveillance System In The United States, Linh Nguyen, Mamunur Rashid, M Mazharul Islam Oct 2020

Pattern Of Health Behavior And Its Association With Self-Rated Health: Evidence From The 2018 Behavioral Risk Factor Surveillance System In The United States, Linh Nguyen, Mamunur Rashid, M Mazharul Islam

Annual Student Research Poster Session

Physical inactivity, tobacco use, and alcohol consumption are linked with increased morbidity and mortality. To improve public health services, we need to keep policymakers updated with health-related issues. Yet, there are limited numbers of recent research on the combination of those lifestyle behaviors as the determinants of self-rated health (SRH) in the US. Therefore, this study (1) examines the pattern of physical activities, smoking, alcohol consumption, and SRH, and (2) investigates the association between the behaviors and SRH status among US citizens. We extracted data from the latest state-based survey of the 2018 Behavioral Risk Factor Surveillance System (BRFSS), which …