Physical Sciences and Mathematics Commons^™

The Santa Clara, 2014-02-13, Santa Clara University

The Santa Clara

No abstract provided.

Genetic Diversity And Demographic History Of Cajanus Spp. Illustrated From Genome-Wide Snps, Rachit K. Saxena, Eric Von Wettberg, Hari D. Upadhyaya, Vanessa Sanchez, Serah Songok, Kulbhushan Saxena, Paul Kimurto, Rajeev K. Varshney

College of Agriculture and Life Sciences Faculty Publications

Understanding genetic structure of Cajanus spp. is essential for achieving genetic improvement by quantitative trait loci (QTL) mapping or association studies and use of selected markers through genomic assisted breeding and genomic selection. After developing a comprehensive set of 1,616 single nucleotide polymorphism (SNPs) and their conversion into cost effective KASPar assays for pigeonpea (Cajanus cajan), we studied levels of genetic variability both within and between diverse set of Cajanus lines including 56 breeding lines, 21 landraces and 107 accessions from 18 wild species. These results revealed a high frequency of polymorphic SNPs and relatively high level of cross-species transferability. …

Identification Of Tetrapeptides From A Mixture Based Positional Scanning Library That Can Restore Nm Full Agonist Function Of The L106p, I69t, I102s, A219v, C271y, And C271r Human Melanocortin-4 Polymorphic Receptors (Hmc4rs), Erica M. Haslach, Huisuo Huang, Marvin Dirain, Ginamarie Debevec, Phaedra Geer, Radleigh Santos, Marc Giulianotti, Clemencia Pinilla, Jon R. Appel, Skye R. Doering, Michael A. Walters, Richard A. Houghten, Carrie Haskell-Luevano

Mathematics Faculty Articles

Human obesity has been linked to genetic factors and single nucleotide polymorphisms (SNPs). Melanocortin-4 receptor (MC4R) SNPs have been associated with up to 6% frequency in morbidly obese children and adults. A potential therapy for individuals possessing such genetic modifications is the identification of molecules that can restore proper receptor signaling and function. These compounds could serve as personalized medications improving quality of life issues as well as alleviating diseases symptoms associated with obesity including type 2 diabetes. Several hMC4 SNP receptors have been pharmacologically characterized in vitro to have a decreased, or a lack of response, to endogenous agonists …

The Santa Clara, 2014-02-06, Santa Clara University

The Santa Clara

No abstract provided.

Randomized And Efficient Authentication In Mobile Environments, Wei Jiang, Dan Lin, Feng Li, Elisa Bertino

Cyber Center Publications

In a mobile environment, a number of users act as a network nodes and communicate with one another to acquire location based information and services. This emerging paradigm has opened up new business opportunities and enables numerous applications such as road safety enhancement, service recommendations and mobile entertainment. A fundamental issue that impacts the success of these applications is the security and privacy concerns raised regarding the mobile users. In that, a malicious user or service provider can track the locations of a user traveled so that other malicious act can be carried out more effectively against the user. Therefore, …

Computational Model For Survey And Trend Analysis Of Patients With Endometriosis : A Decision Aid Tool For Ebm, Salvo Reina, Vito Reina, Franco Ameglio, Mauro Costa, Alessandro Fasciani

COBRA Preprint Series

Endometriosis is increasingly collecting worldwide attention due to its medical complexity and social impact. The European community has identified this as a “social disease”. A large amount of information comes from scientists, yet several aspects of this pathology and staging criteria need to be clearly defined on a suitable number of individuals. In fact, available studies on endometriosis are not easily comparable due to a lack of standardized criteria to collect patients’ informations and scarce definitions of symptoms. Currently, only retrospective surgical stadiation is used to measure pathology intensity, while the Evidence Based Medicine (EBM) requires shareable methods and correct …

Place Events Spring 2014, Place

PLACE Historical Documents

This document describes PLACE events at Linfield College for spring 2014.

Place Events Spring 2014 Highlights, Place

PLACE Historical Documents

This document summarizes highlights of PLACE events at Linfield College for spring 2014.

A Multi-Center, Two-Arm, Single-Blind Randomized Trial Of Two Different Intravenous Fluids During Labor (Poster)., Lisa M. Dapuzzo-Argiriou Md, John C. Smulian Md, Mph, Meredith Rochon Md, Luisa Galdi Do, Jessika Kissling Md, Peter F. Schnatz Do, George Neubert Md, Angel Gonzalez-Rios Md, James Airoldi Md, Mary Anne Carrillo Md, Jaimie Maines Md, Allen R. Kunselman Ms, John Repke Md, Richard S. Legro Md

Department of Obstetrics & Gynecology

No abstract provided.

An Ethnobotanical, Ecological And Lc-Ms-Based Chemometric Investigation Of Phaleria Nisidai, A Traditional Adaptogen Containing Diterpene Esters From Palau, Micronesia, Daniel Kulakowski

Dissertations, Theses, and Capstone Projects

An ethnobotanical, ecological and LC-MS-based chemometric investigation of Phaleria nisidai, a traditional adaptogen containing diterpene esters from Palau, Micronesia

Palau is a country with a rich heritage of traditional medicine still being practiced. One of the most popular and respected remedies in Palau is a tea made from fresh leaves of Phaleria nisidai Kaneh. (Thymelaeaceae). Interviews conducted to determine the use of this plant revealed that it is employed non-specifically to treat a variety of general health concerns. Its use as a prophylactic to keep away sickness, as a 'system cleaner', as well as for strength and energy indicate …

Development Of A Novel Affinity Membrane Purification System For Deoxyribonuclease, Kyle Landry, Robert Levin

Kyle S Landry

Adaptive Pair-Matching In The Search Trial And Estimation Of The Intervention Effect, Laura Balzer, Maya L. Petersen, Mark J. Van Der Laan

Laura B. Balzer

In randomized trials, pair-matching is an intuitive design strategy to protect study validity and to potentially increase study power. In a common design, candidate units are identified, and their baseline characteristics used to create the best n/2 matched pairs. Within the resulting pairs, the intervention is randomized, and the outcomes measured at the end of follow-up. We consider this design to be adaptive, because the construction of the matched pairs depends on the baseline covariates of all candidate units. As consequence, the observed data cannot be considered as n/2 independent, identically distributed (i.i.d.) pairs of units, as current practice assumes. …

Adaptive Pair-Matching In The Search Trial And Estimation Of The Intervention Effect, Laura Balzer, Maya L. Petersen, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

In randomized trials, pair-matching is an intuitive design strategy to protect study validity and to potentially increase study power. In a common design, candidate units are identified, and their baseline characteristics used to create the best n/2 matched pairs. Within the resulting pairs, the intervention is randomized, and the outcomes measured at the end of follow-up. We consider this design to be adaptive, because the construction of the matched pairs depends on the baseline covariates of all candidate units. As consequence, the observed data cannot be considered as n/2 independent, identically distributed (i.i.d.) pairs of units, as current practice assumes. …

Concomitant Socioeconomic, Behavioral, And Biological Factors Associated With The Disproportionate Hiv Infection Burden Among Black Men Who Have Sex With Men In 6 U.S. Cities, Kenneth H. Mayer, Lei Wang, Beryl A. Koblin, Sharon B. Mannheimer, Manya Magnus, +13 Additional Authors

Epidemiology Faculty Publications

Background

American Black men who have sex with men (MSM) are disproportionately affected by HIV, but the factors associated with this concentrated epidemic are not fully understood.

Methods

Black MSM were enrolled in 6 US cities to evaluate a multi-component prevention intervention, with the current analysis focusing on the correlates of being newly diagnosed with HIV compared to being HIV-uninfected or previously diagnosed with HIV.

Results

HPTN 061 enrolled 1553 Black MSM whose median age was 40; 30% self-identified exclusively as gay or homosexual, 29% exclusively as bisexual, and 3% as transgender. About 1/6th(16.2%) were previously diagnosed with HIV (PD); …

The Santa Clara, 2014-01-30, Santa Clara University

The Santa Clara

No abstract provided.

Extracting Vessel Structure From 3d Image Data, Yuchen Zhong

Electronic Thesis and Dissertation Repository

This thesis is focused on extracting the structure of vessels from 3D cardiac images. In many biomedical applications it is important to segment the vessels preserving their anatomically-correct topological structure. That is, the final result should form a tree. There are many technical challenges when solving this image analysis problem: noise, outliers, partial volume. In particular, standard segmentation methods are known to have problems with extracting thin structures and with enforcing topological constraints. All these issues explain why vessel segmentation remains an unsolved problem despite years of research.

Our new efforts combine recent advances in optimization-based methods for image analysis …

Is Hyperbaric Oxygen Therapy An Effective Treatment For Autism? A Review, Daniel Dunleavy, Bruce A. Thyer

Journal of Adolescent and Family Health

Objectives: We review outcome studies regarding the effectiveness of hyperbaric oxygen therapy (HBOT) for Autism Spectrum Disorders (ASD). Method: Studies were identified through electronic bibliographic databases and manual searches of article reference lists. Results: A total of 8 studies met eligibility criteria, consisting of three randomized controlled trials (RCTs), one quasi-experimental study involving a comparison group, two pre-experimental one-group pretest–posttest studies, and two single-system designs. Studies reviewed did not offer credible evidence to suggest that HBOT is an effective treatment for autism. Conclusion: It is premature to call HBOT an effective treatment for Autism and ASD. Individuals clinically treated with …

The Santa Clara, 2014-01-23, Santa Clara University

The Santa Clara

No abstract provided.

The Santa Clara, 2014-01-16, Santa Clara University

The Santa Clara

No abstract provided.

Predictors And Moderators Of Outcomes Of Hiv/Std Sex Risk Reduction Interventions In Substance Abuse Treatment Programs: A Pooled Analysis Of Two Randomized Controlled Trials, Paul Crits-Christoph, Robert Gallop, Jaclyn S. Sadicario, Hannah M. Markell, Donald A. Calsyn, Wan Tang, Hua He, Xin Tu, George Woody

Mathematics Faculty Publications

No abstract provided.

Introduction To Volume 6, Michael Sherr

Journal of Adolescent and Family Health

Introduction to Volume 6

The Santa Clara, 2014-01-09, Santa Clara University

The Santa Clara

No abstract provided.

Assessing The Optimal Virulence Of Malaria‐Targeting Mosquito Pathogens: A Mathematical Study Of Engineered Metarhizium Anisopliae, Bernhard Konrad, Michael R. Lindstrom, Anja Gumpinger, Jielin Zhu, Daniel Coombs

School of Mathematical and Statistical Sciences Faculty Publications and Presentations

Background

Metarhizium anisopliae is a naturally occurring fungal pathogen of mosquitoes. Recently, Metarhizium has been engineered to act against malaria by directly killing the disease agent within mosquito vectors and also effectively blocking onward transmission. It has been proposed that efforts should be made to minimize the virulence of the fungal pathogen, in order to slow the development of resistant mosquitoes following an actual deployment.

Results

Two mathematical models were developed and analysed to examine the efficacy of the fungal pathogen. It was found that, in many plausible scenarios, the best effects are achieved with a reduced or minimal pathogen …

Image Fusion And Axial Labeling Of The Spine, Brandon Miles

Electronic Thesis and Dissertation Repository

In order to improve radiological diagnosis of back pain and spine disease, two new algorithms have been developed to aid the 75% of Canadians who will suffer from back pain in a given year. With the associated medical imaging required for many of these patients, there is a potential for improvement in both patient care and healthcare economics by increasing the accuracy and efficiency of spine diagnosis. A real-time spine image fusion system and an automatic vertebra/disc labeling system have been developed to address this. Both magnetic resonance (MR) images and computed tomography (CT) images are often acquired for patients. …

Relationship Between Altitude And Lithium In Groundwater In The United States Of America: Results Of A 1992–2003 Study, Rebekah S. Huber, Namkug Kim, Carl E. Renshaw, Perry F. Renshaw, Douglas Kondo

Dartmouth Scholarship

Therapeutic dosages of lithium are known to reduce suicide rates, which has led to investigations of confounding environmental risk factors for suicide such as lithium in groundwater. It has been speculated that this might play a role in the potential relationship between suicide and altitude. A recent study in Austria involving geospatial analysis of lithium in groundwater and suicide found lower levels of lithium at higher altitudes. Since there is no reason to suspect this correlation is universal given variation in geology, the current study set out to investigate the relationship between altitude and lithium in groundwater in the United …

Problem Based Learning In Engineering Education: Meeting The Needs Of Industry, Katarina Grolinger

Katarina Grolinger

Industry hires engineers primarily for solving workplace problems; consequently problem solving skills are an essential part of an engineering education. However, industry problems, as well as the environment engineers work in, are often quite different than what students experience at universities. This workshop explores problem based learning, the differences between problems students typically solve in the classroom and the workplace, as well as the strategies for making classroom problems emulate real-world workplace problems. As the main goal of engineering education is to prepare students for work in industry, closing the gap between classroom and workplace problems will result in better …

Research Week 2014, Linda Gardiner

Office of Research Institutional Research and Scholarship

No abstract provided.

The Journal Of Undergraduate Research: Volume 12

The Journal of Undergraduate Research

This is the complete issue of the South Dakota State University Journal of Undergraduate Research, Volume 12.

Skin Lesion Extraction And Its Application, Yanliang Gu

Dissertations, Master's Theses and Master's Reports - Open

In this thesis, I study skin lesion detection and its applications to skin cancer diagnosis. A skin lesion detection algorithm is proposed. The proposed algorithm is based color information and threshold. For the proposed algorithm, several color spaces are studied and the detection results are compared. Experimental results show that YUV color space can achieve the best performance. Besides, I develop a distance histogram based threshold selection method and the method is proven to be better than other adaptive threshold selection methods for color detection. Besides the detection algorithms, I also investigate GPU speed-up techniques for skin lesion extraction and …

Use Of An Electrical Impedance Tomography Method To Detect And Track Fractures In A Gelatin Medium, Evan G. Lucas

Dissertations, Master's Theses and Master's Reports - Open

Electrical impedance tomography is applied to the problem of detecting, locating, and tracking fractures in ballistics gelatin. The hardware developed is intended to be physically robust and based on off-the-shelf hardware. Fractures were created in two separate ways: by shooting a .22 caliber bullet into the gelatin and by injecting saline solution into the gelatin. The .22 caliber bullet created an air gap, which was seen as an increase in resistivity. The saline solution created a fluid filled gap, which was seen as a decrease in resistivity. A double linear array was used to take data for each of the …