Physical Sciences and Mathematics Commons^™

Exploring The Interaction Of Minor-Groove-Binder Netropsin With Dna Using Optical Tweezers, Irbazhusain Shaikh

Honors Program Theses and Projects

Netropsin is an antibiotic that binds in the minor grooves of DNA, which also exhibits anticancer properties. There have been many previous studies that explored the binding of this drug to DNA using traditional methods where an ensemble averaging is used. In this study we explore the interaction of Netropsin with DNA at a single molecule level using dual beam optical tweezers. We trapped and stretched a single DNA molecule using optical tweezers to measure the force experienced by the DNA as a function of extension in the absence and presence of various concentrations of Netropsin. Our results show the …

Glitch Subtraction From Gravitational Wave Data Using Adaptive Spline Fitting, Soumya D. Mohanty, Mohammad A. T. Chowdhury

Physics and Astronomy Faculty Publications and Presentations

Transient signals of instrumental and environmental origins ("glitches") in gravitational wave data elevate the false alarm rate of searches for astrophysical signals and reduce their sensitivity. Glitches that directly overlap astrophysical signals hinder their detection and worsen parameter estimation errors. As the fraction of data occupied by detectable astrophysical signals will be higher in next generation detectors, such problematic overlaps could become more frequent. These adverse effects of glitches can be mitigated by estimating and subtracting them out from the data, but their unpredictable waveforms and large morphological diversity pose a challenge. Subtraction of glitches using data from auxiliary sensors …

Horizon Content Knowledge And Its Integration Into Physics Education Research: Case Study Analysis On Physical Science And Physics Teachers, Trevor A. Robertson

Electronic Theses and Dissertations

Teachers focused on just one year of instruction may neglect what students need most– a coherent structure of learning across disciplines that advances students’ understanding. The topic of coherence has been a major motivator for education research, including investigations in student- teacher interactions, epistemological beliefs, and large-scale curricular reform. One framework of knowledge, horizon content knowledge (HCK), can aid in describing the knowledge a teacher needs to see beyond their own instruction and provide a coherent structure for students.

While horizon content knowledge exists in one of the most widely adopted teacher frameworks of knowledge in mathematics, mathematical knowledge for …

Influence Of Platinum Nanoparticles On Ionic Transport And Hydrogen Reactivity Of Yttria-Stabilized Zirconia Thin Films, Firas Mahyob

Electronic Theses and Dissertations

Yttria-stabilized zirconia (YSZ) is a widely used ceramic material in solid oxide fuel cells, oxygen sensors, and sensing applications due to its high ionic conductivity, chemical inertness, and thermal stability. YSZ is promising active coating for use in miniaturized harsh environment wireless surface acoustic sensors to monitor gases such as H₂. Adding catalytic Pt nanoparticles can enhance gas reactivity and lead to associated film conductivity changes.

In this work, thin films with an (8% Y₂O₃ - 92% ZrO₂) composition were deposited onto piezoelectric langasite substrates using RF magnetron sputtering in Ar:O₂ - …

The Future Is Now In Twisted Coil Polymer Actuators (Tcpa), Ryan Ronquillo

Electronic Theses and Dissertations

This thesis aimed to fabricate and test twisted coiled polymer actuators (TCPA) to understand the mechanical and thermal aspects of this artificial muscle fiber. The purpose of this thesis was to find a linear relationship using the LVDT sensor, fabricating TCPA fibers, and interpreting the data. The project tested whether nylon/polymer could be used as a better artificial muscle fiber.

This research accomplished three goals: (1) designing and fabricating a system capable of creating supercoiled muscle fibers consistently, (2) calibrating the Linear Variable Differential Transformer (LVDT) and Core, and (3) analyzing/interpreting the data of the Twisted Coiled Polymer Actuators (TCPA) …

Improvements To Isru For Rocket Fuel Generation, Justin Sharp

James Madison Undergraduate Research Journal (JMURJ)

The development of efficient in-situ resource utilization (ISRU) technologies is crucial for the establishment of an extraterrestrial, self-sustaining colony. The generation of rocket fuel at potential colony locations is necessary to provide the transportation of people and cargo to and from these locations.Three processes are discussed for the improvement of ISRU methods to generate rocket fuel: electrolysis and electrochemical improvements to the process of crude fuel production, physical and chemical methods for separation of gaseous H2 and O2, and materials and cryogenics engineering for storage and transportation of liquid hydrogen (LH2) and liquid oxygen (LOX). Storage and transportation of cryogenics …

Electron And Other Quarks As Particles Made Of Elementary Particles Of Charge E/3 And Mass Me/6, Polievkt Perov

College of Arts & Sciences Faculty Works

We suggest that the first-generation quarks are not elementary particles, but structures made of a basic elementary particle of charge e/3 and its antiparticle, interacting via an electrostatic force. The structures are suggested for d-quark as consisting of one positive and two negative basic elementary charges, for u-quark as a structure with one negative and three positive basic charges, for an electron as a quark with one positive and four negative basic charges, and for one more quark made of one positive and one negative basic charge. All the suggested structures are in a spinning motion and are stable. The …

Transit Photometry Of Multiple Exoplanet Watch Targets, Jonah Becken

Celebrating Scholarship and Creativity Day (2018-)

Since 1995 exoplanet research has increase dramatically, as a result it is more important than ever to precisely know the dates and times of future transits for repeated observations of a target. NASA’s Exoplanet Watch database and accompanying light curve producing code EXOTIC have the goal of allowing small observatories across the world help find future transits. Under these objective observations of known exoplanet transits where made, using the Saint John’s University observatory, to find the transit midpoint, the ratio of the planet radius and the solar radius, and the period. Using these values, the confirmation that a transit happened …

Radon In Utah Homes, Madison Mackay

Physics Capstone Projects

Radon gas can be found nearly everywhere. It is formed by the decay of radium, which is found in rocks, soil, plants, and animals. Radon gas can become trapped in buildings and is dangerous at high levels. It is particularly known to be high in many areas of the state of Utah. It is important for the average citizen in Utah to understand more about radon and what levels they may be exposed to. An experiment was done to try an alternate, faster method of testing for radon gas. This experiment was performed in several different locations in Utah. While …

Search For B Mesogenesis At Babar, J. P. Lees, V. Poireau, E. Grauges, A. Palano, G. Eigen, D. N. Brown, Yu. G. Kolomensky, M. Fritsch, H. Koch, R. Cheaib, C. Hearty, T. S. Mattison, J. A. Mckenna, R. Y. So, V. E. Blinov, A. R. Buzykaev, V. P. Druzhinin, E. A. Kozyrev, Milind Purohit, Et. Al.

Faculty Publications

A new mechanism has been proposed to simultaneously explain the presence of dark matter and the matter-antimatter asymmetry in the Universe. This scenario predicts exotic B-meson decays into a baryon and a dark-sector antibaryon (ψD) with branching fractions accessible at B factories. We present a search for B→Λψ_D decays using data collected by the BABAR experiment at SLAC. This reaction is identified by fully reconstructing the accompanying B meson and requiring the presence of a single Λ baryon in the remaining particles. No significant signal is observed, and bounds on the B→Λψ …

Optimizing Greenhouses: A Comparative Analysis Of Csb+Sju Greenhouses, Jervon Sands

CSB and SJU Distinguished Thesis

This research aims to determine the optimal design of modern greenhouses through a comparative analysis of three on campus greenhouses. Temperature and humidity measurements as well as physical observations for each site were compared to standard measurements and ideal greenhouse design components. The results of a comparative analysis allowed for the three on-campus greenhouses to be ranked against this section. The trends found in the data confirmed the findings of previous research. Recommendations for operating an optimal greenhouse derived from the analysis and observations along with suggestions for experimental improvements based on a previous study are also included.

Domain Wall Saddle Point Morphology In Ferroelectric Triglycine Sulfate, C. J. Mccluskey, A. Kumar, Alexei Gruverman, I. Luk’Yanchuk, J. M. Gregg

Alexei Gruverman Publications

Ferroelectric domain walls, across which there is a divergence in polarization, usually have enhanced electrical conductivity relative to bulk. However, in lead germanate, head-to-head and tail-to-tail walls are electrically insulating. Recent studies have shown that this is because, when oppositely oriented domains meet, polar divergence is obviated by a combination of domain bifurcation and suspected local dipolar rotation. To explore the uniqueness, or otherwise, of this microstructure, we have used tomographic piezoresponse force microscopy to map three-dimensional domain morphologies in another uniaxial ferroelectric system: triglycine sulfate. This mapping reveals an abundance of domain wall saddle points, which are characteristic of …

Understanding Quantum Field Theory And Standard Model To Explore Beyond Standard Model Physics, Alize Sucsuzer

Honors Program Theses and Projects

Motivated by the goal of participating in astroparticle physics research in graduate school, we aimed to understand the Standard Model of particle physics and the Feynman diagrams through which particle interactions are described, so that we could learn about the properties of certain astroparticles. The axiomatic principle that governs fundamental physics is manifest covariance, implying that the mathematical forms of the physical laws are the same to all observers. Maintaining covariance requires 4-vector representation using group theoretical techniques based on symmetries, as well as a transition from single-particle quantum physics to many-particle quantum field theory (QFT). The Standard Model of …

Preparation, Characterization And Electron Yield Analysis On Highly Insulating Granular Particles, Heather Allen

Physics Capstone Projects

This study focuses on obtaining reliable electron yield measurements of highly insulating granular particles of various shape, size, and composition. Measurements of this kind have long been considered too difficult to collect on granular samples due to experimental complexities leading to a critical knowledge gap in the fundamental electrostatic behaviors of dust. A significant portion of this study was spent on preparing and characterizing granular samples before any type of measurement took place. Particles of varying sizes ranging from ~1 μm to ~100 μm, shapes including cubical, spherical, and angular, and composition including NaCl, MgO, Al₂O₃ and …

Sub-Chandrasekhar Type Ia Supernovae Scenarios With Increased Pathways For Neutronization, Fernando Hernan Rivas

Doctoral Dissertations

Type Ia supernovae are thermonuclear explosions of white dwarfs (WD), electron-degenerate cores of old intermediate mass stars(under 8$M_{\odot}$). Reaching energies of $10^{51}$\si{\erg}, they outshine whole galaxies as they synthesize and distribute most of the iron group elements (IGE; V, Cr, Mn, Fe, Co, Ni) into the interstellar medium, thus being one of the main agents in cosmic chemical evolution. Also, given their notably homogeneous lightcurves, they form the last step in the cosmic distance ladder outdistancing Cepheid variables by orders of magnitude. Though calibration of said lightcurves is dependent on a high number of confirmed events, the limits of statistical …

Fabrication, Measurements, And Modeling Of Semiconductor Radiation Detectors For Imaging And Detector Response Functions, Corey David Ahl

Doctoral Dissertations

In the first part of this dissertation, we cover the development of a diamond semiconductor alpha-tagging sensor for associated particle imaging to solve challenges with currently employed scintillators. The alpha-tagging sensor is a double-sided strip detector made from polycrystalline CVD diamond. The performance goals of the alpha-tagging sensor are 700-picosecond timing resolution and 0.5 mm spatial resolution. A literature review summarizes the methodology, goals, and challenges in associated particle imaging. The history and current state of alpha-tagging sensors, followed by the properties of diamond semiconductors are discussed to close the literature review. The materials and methods used to calibrate the …

Pointing Control And Stabilization Of The High-Energy Uv Laser For Laser-Assisted Charge Exchange, Martin Joseph Kay

Doctoral Dissertations

Laser-Assisted Charge Exchange (LACE) is an experimental method of charge exchange injection into a proton accumulator ring that is being developed at the Spallation Neutron Source (SNS) in Oak Ridge National Laboratory (ORNL) as an alternative to hazardous injection foils. The current scheme of LACE requires a high-energy, low-repetition-rate UV (355 nm) laser beam (140 mJ pulses at 10 Hz) to be transported over 65 meters to the laser-particle interaction point (IP) in a high-radiation area of the accelerator. Thermal effects and other disturbances along the free-space laser transport line cause the beam to slowly drift away from the IP …

Total Absorption Spectroscopy Of Mo-106 And Tc-106, Michael Cooper

Doctoral Dissertations

Total absorption spectroscopy is a method of gamma-ray spectroscopy that has gained prominence in the past several decades, as nuclear data revisions are performed on older nuclear data, which is often incomplete. A strong understanding of underlying nuclear data, particularly fission and beta decay data, is essential for nuclear reactors and nuclear fuel decay heat. This PhD work involves the analysis of fission fragments 106Mo [Mo-106] and 106Tc [Tc-106]. These neutron rich isotopes contribute upwards of 6% of the cumulative fission yield of 241Pu [Pu-241] fission, and 4% of 239Pu [Pu-239] fission. Prior data for these two fission fragments only …

Tdcosmo - Xii. Improved Hubble Constant Measurement From Lensing Time Delays Using Spatially Resolved Stellar Kinematics Of The Lens Galaxy, Anowar J. Shajib, Pritom Mozumdar, Geoff C.-F. Chen, Tommaso Treu, Michele Cappellari, Shawn Knabel, Sherry H. Suyu, Vardha N. Bennert, Joshua A. Frieman, Dominique Sluse, Simon Birrer, Frederic Courbin, Christopher D. Fassnacht, Lizvette Villafaña, Peter R. Williams

Physics

Strong-lensing time delays enable the measurement of the Hubble constant (H₀) independently of other traditional methods. The main limitation to the precision of time-delay cosmography is mass-sheet degeneracy (MSD). Some of the previous TDCOSMO analyses broke the MSD by making standard assumptions about the mass density profile of the lens galaxy, reaching 2% precision from seven lenses. However, this approach could potentially bias the H₀ measurement or underestimate the errors. For this work, we broke the MSD for the first time using spatially resolved kinematics of the lens galaxy in RXJ1131−1231 obtained from the Keck Cosmic …

College Of Natural Sciences Newsletter, March - May 2023, College Of Natural Sciences

College of Natural Sciences Newsletters and Reports

Volume 4, Issue 2

Page 1 Dean's Message
Page 2-7 Awards and Recognition
Page 8 March 3rd Corothers Seminar
Page 9 54th Geography Convention
Page 10 Spring 2023 Day of Scholars
Page 11 2023 URSCAD Snaps
Page 12-14 Media Coverage of CNS
Page 15 Open PRAIRIE Data

Analysis Of The Electrostatic Characteristics Of The Zika Virus Capsid Using Computational Methods, Cassandra Guadalupe Del Rio De Avila

Open Access Theses & Dissertations

Zika virus (ZIKV) is a flavivirus that is usually transmitted through the bite of infected mosquitoes. This virus can cause a variety of neurological disorders, the most common being Guillain-Barré syndrome in adults. Moreover, it is of great concern in pregnant women, since can cause deformities in the brain and other organs of newborns.Studying the structural characteristics of the virus during its mature and infectious phase can provide crucial information on the mechanisms by which it enters and replicates within host cells, as well as its evolution, transmission, and interaction with other living organisms. The symmetric pattern present in the …

Sexual Dimorphism Of Glomerular Capillary Morphology In Rats, Zackarias Coker

Undergraduate Honors Theses

Chronic kidney disease (CKD) progresses faster in males than females; however, the underlying mechanisms remain poorly understood. Sex differences in glomerular capillary morphology has been hypothesized to contribute, in part, to the increased susceptibility to hypertension-induced renal injury and CKD progression in males, but this has not been investigated. The goal of the present study was to assess glomerular capillary morphology in male vs. female rats with intact kidneys and after uninephrectomy (UNX). We hypothesized that glomerular capillary radii (R_CAP) and length (L_CAP) would be greater in male rats.

Male (n=4) and female (n=4) with intact …

Development Of Multi-Configuration Methods On Density Functional Theory Orbitals And Application On The Study Of Dimers, Jose Gustavo Bravo Flores

Open Access Theses & Dissertations

The configuration interaction (CI) methods is an exact method to solve the non relativistic Schrodinger equation, describing the wave function as a linear combination of Slater determinants. Because the computation time grows factorially as the number of electrons, CI is mostly used for relatively small systems. Density functional theory (DFT) rose as one of the most used methods for computational quantum chemistry in the last 30 years. DFT can describe a system's properties with the electron density, which only depends of of three coordinates. Due to its low computational costs it allows one to study bigger systems than CI, however …

Microscopic And Spectroscopic Analysis Of Nordihydroguaiaretic Acid Effect On Astrocytes, Lizbeth Vanessa Martinez Lopez

Open Access Theses & Dissertations

Astrocytes, one of the most abundant cell components in the central nervous system (CNS), have been a research target in the last few years. Several studies have found that astrocytes are not only mere supporters of neurons but also of essential processes developed in the CNS. Their malfunction could induce neurodegenerative diseases and brain tumors. Thus, further understanding of astrocytes and their role is of high interest to develop possible new treatments and methods of disease diagnosis, especially in brain cancer. The plant Larrea tridentata (La Gobernadora in Mexico or Creosote bush in the United States) is known to have …

Studies Of The Ionosphere-Thermosphere Responses To Multi-Scale Energy Deposition Processes, Haonan Wu

All Dissertations

The Ionosphere-Thermosphere (I-T) system is greatly affected by the magnetospheric energy deposition from above and subjected to forcing from the lower atmosphere simultaneously. A central problem in studying the coupled I-T system is to analyze the multi-scale processes naturally embedded in both ways. Magnetospheric energy input such as auroral precipitation and electric field demonstrates multi-scale structures during magnetic storms, resulting in multi-scale I-T responses when deposited into the I-T system. To better quantify the multi-scale aurora and electric field, we developed a new data assimilation model based on a multi-resolution Gaussian process model to synthesize empirical models and observational data …

Designing Noncentrosymmetric Multifunctional Materials, Ebube Oyeka

All Dissertations

Noncentrosymmetric (NCS) materials with crystal lattices lacking spatial inversion symmetry display a wide range of exciting functionalities. This dissertation covers two classes of functional NCS materials: magnetic skyrmion-host compounds and multifunctional materials. Magnetic skyrmion and multifunctional materials combining optical and magnetic responses are providing avenues for developing and optimizing the performance of electronic devices that can have uses in memory storage, laser technology, medicine, sensors, etc. The formation of skyrmions is driven by asymmetric Dzyaloshinskii–Moriya (DM) interaction facilitated by broken spatial inversion symmetry and large spin-orbit coupling (SOC), while multiple functionalities arise when spin carriers and optical chromophores are optimally …

The Search For Heavily Obscured Active Galactic Nuclei In The Local Universe, Ross Silver

All Dissertations

Active galactic nuclei (AGN) are supermassive black holes (SMBHs) in the center of galaxies that accrete surrounding gas and emit across the entire electromagnetic spectrum. They are the most energetic persistent emitters in the Universe, capable of outshining their host galaxies despite their emission originating from a region smaller than our Solar System. AGN were some of the first sources discovered that helped teach us that there were galaxies outside of our own, and they proved the existence of black holes. Moreover, AGN can give us valuable insights into other branches of astrophysics. For example, they can be used to …

Machine Learning-Based Data And Model Driven Bayesian Uncertanity Quantification Of Inverse Problems For Suspended Non-Structural System, Zhiyuan Qin

All Dissertations

Inverse problems involve extracting the internal structure of a physical system from noisy measurement data. In many fields, the Bayesian inference is used to address the ill-conditioned nature of the inverse problem by incorporating prior information through an initial distribution. In the nonparametric Bayesian framework, surrogate models such as Gaussian Processes or Deep Neural Networks are used as flexible and effective probabilistic modeling tools to overcome the high-dimensional curse and reduce computational costs. In practical systems and computer models, uncertainties can be addressed through parameter calibration, sensitivity analysis, and uncertainty quantification, leading to improved reliability and robustness of decision and …

Effects Of Factors On The Market Price Of The Shares Using Design Of Experiment, Amir Ahmad Dar, Mohammad Shahfaraz Khan, Imran Azad, Tanveer Ahmad Tarray, N. Anuradha, Qaiser Farroq Dar

Applied Mathematics & Information Sciences

When the cost of capital, dividends and the price of the share at the beginning is known, Modigliani and Miller’s model can be used to estimate the price of the share at the end of the period. A design of experiment (Taguchi’s orthogonal array) is used in order to investigate the impact of three parameters on the price of the share at the end of the period. The main aim of this research article is to find which parameter is more significant on the price of the share at the end of the period. Taguchi’s methodology of design of the …

Modeling, Simulation And Control Of Microrobots For The Microfactory., Zhong Yang

Electronic Theses and Dissertations

Future assembly technologies will involve higher levels of automation in order to satisfy increased microscale or nanoscale precision requirements. Traditionally, assembly using a top-down robotic approach has been well-studied and applied to the microelectronics and MEMS industries, but less so in nanotechnology. With the boom of nanotechnology since the 1990s, newly designed products with new materials, coatings, and nanoparticles are gradually entering everyone’s lives, while the industry has grown into a billion-dollar volume worldwide. Traditionally, nanotechnology products are assembled using bottom-up methods, such as self-assembly, rather than top-down robotic assembly. This is due to considerations of volume handling of large …