Physical Sciences and Mathematics Commons^™

Heterojunction Engineering For Next Generation Hybrid Ii-Vi Materials, Thor Garcia

Dissertations, Theses, and Capstone Projects

Molecular Beam Epitaxy(MBE) is a versatile thin film growth technique with monolayer control of crystallization. The flexibility and precision afforded by the technique allows for unique control of interfaces and electronic structure of the films grown. This facilitates the realization of novel devices and structures within a research environment normally only achieved though complex industrial processes. In the past, the control of each interface in MBE has been explored to great benefit. In this work, we study the control of these interfaces so as to increase the performance of novel devices material systems. This dissertation focuses on two main areas …

Continuum Electrostatics Analysis Of The Kok Cycle Of Photosystem Ii, Witold Szejgis

Dissertations, Theses, and Capstone Projects

The Kok cycle is catalytic process by which the oxygen-evolving complex (OEC) of photosystem II (PSII) oxidizes two water molecules forming oxygen. Four OEC oxidation states (S₀ to S₃) in the Kok cycle precede the final product formation in the S₄ state. Here a semi-empirical classical electrostatics analysis is applied to S₀ to S₃ states of the OEC is used to estimate the electrochemical midpoints for each S-state transition and the proton loss coupled to oxidation. To account for geometrical rearrangement within the cluster during Kok cycle optimized QM/MM geometries are used for each …

Machine Learning Approach To Retrieving Physical Variables From Remotely Sensed Data, Fazlul Shahriar

Dissertations, Theses, and Capstone Projects

Scientists from all over the world make use of remotely sensed data from hundreds of satellites to better understand the Earth. However, physical measurements from an instrument is sometimes missing either because the instrument hasn't been launched yet or the design of the instrument omitted a particular spectral band. Measurements received from the instrument may also be corrupt due to malfunction in the detectors on the instrument. Fortunately, there are machine learning techniques to estimate the missing or corrupt data. Using these techniques we can make use of the available data to its full potential.

We present work on four …

A Combinatorial Framework For Multiple Rna Interaction Prediction, Syed Ali Ahmed

Dissertations, Theses, and Capstone Projects

The interaction of two RNA molecules involves a complex interplay between folding and binding that warranted recent developments in RNA-RNA interaction algorithms. However, biological mechanisms in which more than two RNAs take part in an interaction also exist.

A typical algorithmic approach to such problems is to find the minimum energy structure. Often the computationally optimal solution does not represent the biologically correct structure of the interaction. In addition, different biological structures may be observed, depending on several factors. Furthermore, scoring techniques often miss critical details about dependencies within different parts of the structure, which typically leads to lower scores …

Characterization Of Hydrophobic Interactions Of Polymers With Water And Phospholipid Membranes Using Molecular Dynamics Simulations, Mihaela Drenscko

Dissertations, Theses, and Capstone Projects

Polymers and lipid membranes are both essential soft materials. The structure and hydrophobicity/hydrophilicity of polymers, as well as the solvent they are embedded in, ultimately determines their size and shape. Understating the variation of shape of the polymer as well as its interactions with model biological membranes can assist in understanding the biocompatibility of the polymer itself. Computer simulations, in particular molecular dynamics, can aid in characterization of the interaction of polymers with solvent, as well as polymers with model membranes. In this thesis, molecular dynamics serve to describe polymer interactions with a solvent (water) and with a lipid membrane. …

A Realization Of Modernity: Case Studies In Connectivity And Time, Mari Gorman

Dissertations, Theses, and Capstone Projects

My stated goal in applying to The Graduate Center was to explore my previous research in diverse fields of study. This research, the result of a formal investigation of acting, was and still is centrally focused on the subject of relationship itself, relationships being what actors create. In pursuit of a greater understanding of the essential nature of relationship in practical terms, a self-organizing complex system that constitutes universal relationship was unexpectedly discovered. As such, this system has been shown to offer solutions to many outstanding problems in diverse areas of study. The Liberal Studies program track, Approaches to Modernity …

Machine Learning Algorithms For Automated Satellite Snow And Sea Ice Detection, George Bonev

Dissertations, Theses, and Capstone Projects

The continuous mapping of snow and ice cover, particularly in the arctic and poles, are critical to understanding the earth and atmospheric science. Much of the world's sea ice and snow covers the most inhospitable places, making measurements from satellite-based remote sensors essential. Despite the wealth of data from these instruments many challenges remain. For instance, remote sensing instruments reside on-board different satellites and observe the earth at different portions of the electromagnetic spectrum with different spatial footprints. Integrating and fusing this information to make estimates of the surface is a subject of active research.

In response to these challenges, …

Involute Analysis: Virtual Discourse, Memory Systems And Archive In The Involutes Of Thomas De Quincey, Kimberley A. Garcia

Dissertations, Theses, and Capstone Projects

Thomas De Quincey’s involutes inform metaphysical thought on memory and language, particularly concerning multiplicity and the virtual, repetition and difference. When co-opting the mathematic and mechanic involute in Suspiria de Profundis, De Quincey generates an interdisciplinary matrix for the semiotics underpinning his philosophy of language and theory of memory and experience. Involutes entangle and reproduce. De Quincey’s involute exposes the concrete and actual through which all experience accesses the abstract or virtual. The materiality of their informatics and technics provides a literary model and theoretical precursor to a combination of archive and systems theory. The textuality of involute system(s)—both …

Control Of Light-Matter Interaction In 2d Semiconductors, Zheng Sun

Dissertations, Theses, and Capstone Projects

In this thesis we discuss the control of light matter interaction in low dimensional nanostructure cavity light confining structures. These structures have controllable dispersion properties through design which can be exploited to modify the interaction of light and matter. We will discuss two different types of light confining microcavities: a dielectric cavity and a metal cavity. The specific design of the cavity gives rise to the confinement of the electric field in the center where the nano-materials are placed. In this work, the main material was on the new class of two- dimensional semiconductors of transition metal dichalcogenides (TMDs). Due …

The Formation Of Fine-Grained Chondrule Rims In Unequilibrated Ordinary Chondrites, John Bigolski

Dissertations, Theses, and Capstone Projects

Fine-grained rims are ubiquitous, non-igneous, features that completely or partially envelope the majority of chondrules within the least equilibrated of the unequilibrated ordinary chondrites (UOCs). A detailed examination of such rims in 4 UOC samples less than petrologic type 3.2 was conducted in order to 1) characterize the relative distribution of rims within chondrite samples, 2) inspect differences between fine-grained rims and adjacent matrix material, 3) petrologically analyze the rims and their relationships with chondrule cores, 4) characterize an ungrouped UOC, Northwest Africa 5717, 5) conduct a microanalytical investigation of rim / matrix boundaries to discern relative chronologies of fine-grained …

A Stochastic Mesoscale Model Of Transiently Networked Fluids., Lin Zhou, L. Pamela Cook

Publications and Research

Macroscale models of physically networked fluids suffer from the inability to connect directly to mesoscale processes due to nonlinearity and thus the need for closure approximations. In this paper physically networked complex fluids are modeled stochastically at the mesoscale, thus avoiding the need for closure assumptions. In the modeling and simulations the network consists of linear chains of Hookean bead-spring dumbbells. The linear chains break and reform stochastically subject to prescribed local attractive potentials. In the simulations the topology of the network is tracked allowing for quantification of the distribution of chain lengths and of individual dumbbell stretch. This formulation …

Synthesis And Evaluation Of Tetrahydroprotoberberines As Dopamine Receptor Ligands, Satishkumar V. Gadhiya

Dissertations, Theses, and Capstone Projects

Dopamine (DA) receptors belong to the G-protein coupled receptors (GPCRs) family, divided in to two groups based on their high homology transmembrane domains; D1-like DA receptors (D1, D5) and D2-like DA receptors (D2-D4). DA receptor specific ligands have been exploited as a means for studying the prognosis and curing several CNS disorders. Though several efforts have been devoted to discover selective and potent DA receptor ligands, complete selectivity within the DA receptor subtypes remains a challenge.

Tetrahydroprotoberberines (THPBs) are a group of naturally occurring tetracyclic alkaloids that belong to the tetrahydroisoquinoline family. A wide range of biological activities are associated …

Some Metric Properties Of The Teichmüller Space Of A Closed Set In The Riemann Sphere, Nishan Chatterjee

Dissertations, Theses, and Capstone Projects

Let E be an infinite closed set in the Riemann sphere, and let T(E) denote its Teichmüller space. In this dissertation we study some metric properties of T(E). We prove Earle's form of Teichmüller contraction for T(E), holomorphic isometries from the open unit disk into T(E), extend Earle's form of Schwarz's lemma for classical Teichmüller spaces to T(E), and finally study complex geodesics and unique extremality for T(E).

Nonlinear Optical Studies Of Defects And Domain Structures In Perovskite-Type Dielectric Ceramics, David J. Ascienzo

Dissertations, Theses, and Capstone Projects

In order to improve future generations of dielectric capacitors a deeper understanding of voltage-induced dielectric breakdown and electrical energy storage limitations is required. This dissertation presents the use of far-field optical second harmonic generation (SHG) polarimetry for probing structural defects and polar domains in linear and nonlinear perovskite dielectric ceramics. We investigated the formation of electric field-induced structural distortions at pristine Fe-doped SrTiO₃ (Fe:STO) electrode interfaces, structural defect and strain formation due to oxygen vacancy migration in electrodegraded Fe:STO single crystals, and mixed tetragonal and rhombohedral phase domains in ferroelectric Zr-doped BaTiO₃ (BZT) films exhibiting excellent …

Stereospecific Electrophilic Fluorination Of Alkylcarbastannatrane Reagents, Xinghua Ma

Dissertations, Theses, and Capstone Projects

The introduction of fluorine atoms into organic molecules significantly changes their physical, chemical, and biological properties. Fluorinated organic compounds are used as pharmaceuticals, agrochemicals, materials, and tracers for positron emission tomography (PET). For example, the site-specific fluorination of drugs can block sites of phase I metabolism by cytochrome P450 enzymes as well as improve target-binding affinities. In view of the unique features of fluorine-containing compounds, there has been increasing interest in the development of novel methods for the synthesis of fluorinated molecules, especially the site-specific monofluorination of complex molecules. Herein, we present the enantiospecific conversion of chiral secondary alkylcarbastannatranes into …

Secure And Efficient Delegation Of A Single And Multiple Exponentiations To A Single Malicious Server, Matluba Khodjaeva

Dissertations, Theses, and Capstone Projects

Group exponentiation is an important operation used in many cryptographic protocols, specifically public-key cryptosystems such as RSA, Diffie Hellman, ElGamal, etc. To expand the applicability of group exponentiation to computationally weaker devices, procedures were established by which to delegate this operation from a computationally weaker client to a computationally stronger server. However, solving this problem with a single, possibly malicious, server, has remained open since a formal cryptographic model was introduced by Hohenberger and Lysyanskaya in 2005. Several later attempts either failed to achieve privacy or only achieved constant security probability.

In this dissertation, we study and solve this problem …

Morphogenesis And Growth Driven By Selection Of Dynamical Properties, Yuri Cantor

Dissertations, Theses, and Capstone Projects

Organisms are understood to be complex adaptive systems that evolved to thrive in hostile environments. Though widely studied, the phenomena of organism development and growth, and their relationship to organism dynamics is not well understood. Indeed, the large number of components, their interconnectivity, and complex system interactions all obscure our ability to see, describe, and understand the functioning of biological organisms.

Here we take a synthetic and computational approach to the problem, abstracting the organism as a cellular automaton. Such systems are discrete digital models of real-world environments, making them more accessible and easier to study then their physical world …

Computational Investigation Of The Pore Formation Mechanism Of Beta-Hairpin Antimicrobial Peptides, Richard Lipkin

Dissertations, Theses, and Capstone Projects

β-hairpin antimicrobial peptides (AMPs) are small, usually cationic peptides that provide innate biological defenses against multiple agents. They have been proposed as the basis for novel antibiotics, but their pore formation has not been directly observed on a molecular level. We review previous computational studies of peptide-induced membrane pore formation and report several new molecular dynamics simulations of β-hairpin AMPs to elucidate their pore formation mechanism. We simulated β-barrels of various AMPs in anionic implicit membranes, finding that most of the AMPs’ β-barrels were not as stable as those of protegrin. We also performed an optimization study of protegrin β-barrels …

Nuclear Magnetic Resonance Studies Of Electrode And Electrolyte Materials For Li-Ion Batteries, Lisa Cirrincione

Dissertations, Theses, and Capstone Projects

In this thesis, Nuclear Magnetic Resonance (NMR) spectroscopic techniques are used to study lithium electrode and electrolyte materials for advanced rechargeable lithium ion batteries. Three projects are described in this thesis. The first involves ²³Na and ³⁷Al static and magic angle spinning NMR studies of NaAlH₄/C anode materials for advanced rechargeable batteries. The second project is a study of paramagnetic lithium transition-metal phosphate cathode materials for Li-ion batteries, where ⁷Li, and ³¹P single crystal NMR was used in order to obtain detailed information on the local electronic and magnetic environments. The third project investigates …

Economic Burden, Mortality, And Institutionalization In Patients Newly Diagnosed With Alzheimer’S Disease, Christopher M. Black, Howard Fillit, Lin Xie, Xiaohan Hu, M. Furaha Kariburyo, Baishali M. Ambegaonkar, Onur Baser, Huseyin Yuce, Rezaul K. Khandker

Publications and Research

Background: Current information is scarce regarding comorbid conditions, treatment, survival, institutionalization, and health care utilization for Alzheimer’s disease (AD) patients.

Objectives: Compare all-cause mortality, rate of institutionalization, and economic burden between treated and untreated newly-diagnosed AD patients.

Methods: Patients aged 65–100 years with ≥1 primary or ≥2 secondary AD diagnoses (ICD-9-CM:331.0] with continuous medical and pharmacy benefits for ≥12 months pre-index and ≥6 months post-index date (first AD diagnosis date) were identified from Medicare fee-for-service claims 01JAN2011–30JUN2014. Patients with AD treatment claims or AD/ADrelated dementia diagnosis during the pre-index period were excluded. Patients were assigned to treated and untreated cohorts …

The Effect Of Hydrogen Bonding In Enhancing The Ionic Affinities Of Immobilized Monoprotic Phosphate Ligands, Spiro D. Alexandratos, Xiaoping Liu

Publications and Research

Environmental remediation requires ion-selective polymers that operate under a wide range of solution conditions. In one example, removal of trivalent and divalent metal ions from waste streams resulting from mining operations before they enter the environment requires treatment at acidic pH. The monoethyl ester phosphate ligands developed in this report operate from acidic solutions. They have been prepared on polystyrene-bound ethylene glycol, glycerol, and pentaerythritol, and it is found that intra-ligand hydrogen bonding affects their metal ion affinities. The affinity for a set of trivalent (Fe(III), Al(III), La(III), and Lu(III)) and divalent (Pb(II), Cd(II), Cu(II), and Zn(II)) ions is greater …

Zero Textbook Cost Syllabus For Cis 3367 (Spreadsheet Applications In Business), Soniya Dsouza

Open Educational Resources

The primary focus of this course is to learn how to construct and use powerful spreadsheets for effective managerial decision-making. This course is mostly project- oriented with a dual focus on spreadsheet engineering and quantitative modeling of financial applications. Students will learn to develop powerful spreadsheet models and perform data analysis using Pivot Tables, VLookUp, Data Validation techniques and Sub Total functions. Students will also learn how to enhance spreadsheets by creating dashboards on financial data. The Visual Basic (macro) concepts will also be introduced to students. With the knowledge and hands-on experience of these concepts, students will be prepared …

On The Pursuit Of Relevance In Standards-Based Curriculum Development: The Ccny Approach, Angelo Lampousis

Publications and Research

The Society for Standards Professionals (SES) has a significant history of documenting the use of standards in research and academia. For instance, during the 62nd Annual SES Conference in 2013 in Savannah, Georgia, the author participated in such a session highlighting examples of relationships between academic institutions, government, and standards developing organizations. In this article, we attempt to capture the current advances made from similar relationships specific to our home institution, the City College of New York (CCNY) of the City University of New York (CUNY.) These advances have become possible through a grant issued under the Standards Services Curricula …

Digital Anti-Forensics: An Implementation And Examination, Stephanie Dachs

Student Theses

The rise of computer use and technical adeptness by the general public in the last two decades are undeniable. With greater use comes a greater possibility for misuse, evidenced by today’s incredible number of crimes involving computers as well as the growth in severity from that of cyber hooliganism to cyber warfare. Although frequently utilized for privacy and security purposes, the vast range of anti-forensic techniques has contributed to the ability for hackers and criminals to obstruct computer forensic investigations.

Understanding how anti-forensics may alter important and relevant data on an electronic device will prove useful for the success and …

Introduction To Gis Using Open Source Software, 8th Ed, Frank Donnelly

Open Educational Resources

This tutorial was created to accompany the GIS Practicum, a day-long workshop offered by the Newman Library at Baruch College CUNY that introduces participants to geographic information systems (GIS) using the open source software QGIS. The practicum introduces GIS as a concept for envisioning information and as a tool for conducting geographic analyses and creating maps. Participants learn how to navigate a GIS interface, how to prepare layers and conduct a basic geographic analysis, and how to create thematic maps. This tutorial was written using QGIS version 2.18 "Las Palmas", a cross-platform (Windows, Mac, Linux) desktop GIS software package.

Content Analysis Of Data Science Graduate Programs In The U.S., Duo Li, Elizabeth Milonas, Qiping Zhang

Publications and Research

Data science is an emerging academic field (Paul & Aithal, 2018), which has its origins in “Big Data/Cloud Computing” and complexity science domains. Data Science is about managing large and complex data (Big Data management) and analytics technologies (Paul & Aithal, 2018). Data, technology, and people are the three pillars of data science. In addition, Data Science is composed of three key areas: analytics, infrastructure, and data curation (Tang & Sae-Lim, 2016). Stanton (2012) defined data science as “an emerging area of work concerned with the collection, preparation, analysis, visualization, management, and preservation of large collections of information (Song & …

Chelator-Free Radiolabeling Of Serrs Nanoparticles For Whole-Body Pet And Intraoperative Raman Imaging, Matthew A. Wall, Travis Shaffer, Stefan Harmsen, Darjus-Felix Tschaharganeh, Chun-Hao Huang, Scott W. Lowe, Charles Michael Drain, Moritz F. Kircher

Publications and Research

A single contrast agent that offers whole-body non-invasive imaging along with the superior sensitivity and spatial resolution of surface-enhanced resonance Raman scattering (SERRS) imaging would allow both pre-operative mapping and intraoperative imaging and thus be highly desirable. We hypothesized that labeling our recently reported ultrabright SERRS nanoparticles with a suitable radiotracer would enable pre-operative identification of regions of interest with whole body imaging that can be rapidly corroborated with a Raman imaging device or handheld Raman scanner in order to provide high precision guidance during surgical procedures. Here we present a straightforward new method that produces radiolabeled SERRS nanoparticles for …

Tumor Necrosis Factor Dynamically Regulates The Mrna Stabilome In Rheumatoid Arthritis Fibroblast-Like Synoviocytes, Konstantinos Loupasakis, David Kuo, Upneet K. Sokhi, Christopher Sohn, Bethany Syracuse, Eugenia G. Giannopoulou, Sung Ho Park, Hyelim Kang, Gunnar Rätsch, Lionel B. Ivashkiv, George D. Kalliolias

Publications and Research

During rheumatoid arthritis (RA), Tumor Necrosis Factor (TNF) activates fibroblast-like synoviocytes (FLS) inducing in a temporal order a constellation of genes, which perpetuate synovial inflammation. Although the molecular mechanisms regulating TNF-induced transcription are well characterized, little is known about the impact of mRNA stability on gene expression and the impact of TNF on decay rates of mRNA transcripts in FLS. To address these issues we performed RNA sequencing and genome-wide analysis of the mRNA stabilome in RA FLS. We found that TNF induces a biphasic gene expression program: initially, the inducible transcriptome consists primarily of unstable transcripts but progressively switches …

Distinct Properties Of The Triplet Pair State From Singlet Fission, M. Tuan Trinh, Andrew Pinkard, Andrew B. Pun, Samuel N. Sanders, Elango Kumarasamy, Matthew Y. Sfeir, Luis M. Campos, Xavier Roy, X.-Y. Zhu

Publications and Research

Singlet fission, the conversion of a singlet exciton (S₁) to two triplets (2 × T₁), may increase the solar energy conversion efficiency beyond the Shockley-Queisser limit. This process is believed to involve the correlated triplet pair state ¹(TT). Despite extensive research, the nature of the ¹(TT) state and its spectroscopic signature remain actively debated. We use an end-connected pentacene dimer (BP0) as a model system and show evidence for a tightly bound ¹(TT) state. It is characterized in the near-infrared (IR) region (~1.0 eV) by a distinct excited-state absorption (ESA) spectral feature, which …

Holography For Field Theory Solitons, Sophia K. Domokos, Andrew B. Royston

Publications and Research

We extend a well-known D-brane construction of the AdS/dCFT correspondence to non-abelian defects. We focus on the bulk side of the correspondence and show that there exists a regime of parameters in which the low-energy description consists of two approximately decoupled sectors. The two sectors are gravity in the ambient spacetime, and a six-dimensional supersymmetric Yang-Mills theory. The Yang-Mills theory is defined on a rigid AdS4 S2 background and admits sixteen supersymmetries. We also consider a one-parameter deformation that gives rise to a family of Yang-Mills theories on asymptotically AdS4 S2 spacetimes, which are invariant under eight supersymmetries. With future …