Physical Sciences and Mathematics Commons^™

Electric Power And The Global Economy: Advances In Database Construction And Sector Representation, Jeffrey C. Peters

Open Access Dissertations

The electricity sector plays a crucial role in the global economy. The sector is a major consumer of fossil fuel resources, producer of greenhouse gas emissions, and an important indicator and correlate of economic development. As such, the sector is a primary target for policy-makers seeking to address these issues. The sector is also experiencing rapid technological change in generation (e.g. renewables), primary inputs (e.g. horizontal drilling and hydraulic fracturing), and end-use efficiency. This dissertation seeks to further our understanding of the role of the electricity sector as part of the dynamic global energy-economy, which requires significant research advances in …

Statistical Analysis Of The Effectiveness Of Seawalls And Coastal Forests In Mitigating Tsunami Impacts In Iwate And Miyagi Prefectures, Roshanak Nateghi, Jeremy D. Bricker, Seth D. Guikema, Akane Bessho

School of Industrial Engineering Faculty Publications

The Pacific coast of the Tohoku region of Japan experiences repeated tsunamis, with the most recent events having occurred in 1896, 1933, 1960, and 2011. These events have caused large loss of life and damage throughout the coastal region. There is uncertainty about the degree to which seawalls reduce deaths and building damage during tsunamis in Japan. On the one hand they provide physical protection against tsunamis as long as they are not overtopped and do not fail. On the other hand, the presence of a seawall may induce a false sense of security, encouraging additional development behind the seawall …

Missing Gene Identification Using Functional Coherence Scores, Meghana Chitale, Ishita K. Khan, Daisuke Kihara

Department of Biological Sciences Faculty Publications

Reconstructing metabolic and signaling pathways is an effective way of interpreting a genome sequence. A challenge in a pathway reconstruction is that often genes in a pathway cannot be easily found, reflecting current imperfect information of the target organism. In this work, we developed a new method for finding missing genes, which integrates multiple features, including gene expression, phylogenetic profile, and function association scores. Particularly, for considering function association between candidate genes and neighboring proteins to the target missing gene in the network, we used Co-occurrence Association Score (CAS) and PubMed Association Score (PAS), which are designed for capturing functional …

Improved Prediction Of Severe Thunderstorms Over The Indian Monsoon Region Using High-Resolution Soil Moisture And Temperature Initialization, K. K. Osuri, R. Nadimpalli, U. C. Mohanty, F. Chen, M. Rajeevan, Dev Niyogi

Department of Earth, Atmospheric, and Planetary Sciences Faculty Publications

The hypothesis that realistic land conditions such as soil moisture/soil temperature (SM/ST) can significantly improve the modeling of mesoscale deep convection is tested over the Indian monsoon region (IMR). A high resolution (3 km foot print) SM/ST dataset prepared from a land data assimilation system, as part of a national monsoon mission project, showed close agreement with observations. Experiments are conducted with (LDAS) and without (CNTL) initialization of SM/ST dataset. Results highlight the significance of realistic land surface conditions on numerical prediction of initiation, movement and timing of severe thunderstorms as compared to that currently being initialized by climatological fields …

A Study Of Alterations In Dna Epigenetic Modifications (5mc And 5hmc) And Gene Expression Influenced By Simulated Microgravity In Human Lymphoblastoid Cells, Basudev Chowdhury, Arun Seetharam, Zhiping Wang, Yunlong Liu, Amy C. Lossie, Jyothi Thimmapuram

Cyber Center Publications

Cells alter their gene expression in response to exposure to various environmental changes. Epigenetic mechanisms such as DNA methylation are believed to regulate the alterations in gene expression patterns. In vitro and in vivo studies have documented changes in cellular proliferation, cytoskeletal remodeling, signal transduction, bone mineralization and immune deficiency under the influence of microgravity conditions experienced in space. However microgravity induced changes in the epigenome have not been well characterized. In this study we have used Next-generation Sequencing (NGS) to profile ground-based “simulated” microgravity induced changes on DNA methylation (5-methylcytosine or 5mC), hydroxymethylation (5-hydroxymethylcytosine or 5hmC), and simultaneous gene …

Size And Chemistry Selective Membranes From Block Polymer Templates, Ryan A. Mulvenna

Open Access Dissertations

The use of block polymers continues to gain attention with their myriad applications in industry for advanced applications in biology, medicine, electronics, and separations. The ability of block polymers to self assemble into ordered states on the nanometer level makes these materials suitable for applications that mandate structural order on this scale. By tuning the chemistry of these block domains, we may explore their utilization for advanced separations.

In this dossier, we detail the efforts into the controlled radical polymerization of polyisoprene-b-polystyrene-b-poly( N,N-dimethylacrylamide) (PI-PS-PDMA) via. a facile reversible addition-fragmentation chain transfer (RAFT) mechanism. For this …

Tailoring Optical And Plasmon Resonances In Core-Shell And Core-Multishell Nanowires, Sarath Ramadurgam

Open Access Dissertations

Semiconductor nanowires (NWs) are sub-wavelength structures which exhibit strong optical (Mie) resonances in the visible range. In addition to such optical resonances, the localized surface plasmon resonances (LSPR) in metal and semiconductor (or dielectric) based core-shell (CS) and core-multishell (CMS) NWs can be tailored to achieve novel negative-index metamaterials (NIM), extreme absorbers, invisibility cloaks and sensors. Particularly, in this dissertation, the versatility of CS and CMS NWs for the design of negative-index metamaterials in the visible range and, plasmonic light harvesting in ultrathin photocatalyst layers for water splitting are studied.

Utilizing the LSPR in the metal layer and the magnetic …

System-Wide Prediction Of General, All-Cause, Preventable Hospital Readmissions, Ken Musselman, Brandon Pope, Steve Witz, Zhiyi Tian, Lingsong Zhang, Linda Leon, Ann Davis

RCHE Publications

Existing studies of hospital readmissions typically focus on specific diagnoses, age groups, discharge dispositions, payer classes, or hospitals, and often use small samples. It is not clear how predictive models generated from such studies generalize across diseases, hospitals, or time periods. In this study, a logistic regression model of readmission risk within 30 days based on hospital administrative data was constructed and validated across hospitals and time periods. The hospitals included both general and specialty hospitals such as long-term care, women’s, and children’s hospitals. The administrative data included information on patient’s demographics, diagnoses, procedures, and discharge disposition. Derivation and validation …

Pre-Mission Input Requirements To Enable Successful Sample Collection By A Remote Field/Eva Team, Barbara A. Cohen, Darlene S. S. Lim, Kelsey E. Young, Anna Brunner, Richard C. Elphic, Audrey Horne, Mary C. Kerrigan, Gordon O. Osinski, John R. Skok, Steven W. Squyres, David Saint-Jacques, Jennifer L. Heldmann

Journal of Human Performance in Extreme Environments

We used a field excursion to the West Clearwater Lake Impact structure as an opportunity to test factors that contribute to the decisions a remote field team (for example, astronauts conducting extravehicular activities (EVA) on planetary surfaces) makes while collecting samples for return to Earth. We found that detailed background on the analytical purpose of the samples, provided to the field team, enables them to identify and collect samples that meet specific analytical objectives. However, such samples are not always identifiable during field reconnaissance activities, and may only be recognized after outcrop characterization and interpretation by crew and/or science team …

Web Based Cyber Forensics Training For Law Enforcement, Nick Sturgeon

Purdue Polytechnic Masters Theses

Training and education are two of the most important aspects within cyber forensics. These topics have been of concern since the inception of the field. Training law enforcement is particularly important to ensure proper execution of the digital forensics process. It is also important because the proliferation of technology in to society continues to grow at an exponential rate. Just as technology is used for good there are those that will choose to use it for criminal gains. It is critical that Law Enforcement have the tools and training in cyber forensics. This research looked to determine if web based …

The Impact Of Crystal Morphology On The Thermal Responses Of Ultrasonically-Excited Energetic Materials, J. K. Miller, J. O. Mares, I. E. Gunduz, Steven F. Son, Jeff Rhoads

Purdue Energetics Research Center Articles

The ability to detect explosive materials may be significantly enhanced with local increases in vapor pressure caused by an elevation of the materials'temperature. Recently, ultrasonic excitation has been shown to generate heat within plastic-bonded energetic materials. To investigate the impact of crystal morphology on this heating, samples of elastic binder are implanted with single ammonium perchlorate crystals of two distinct shape groups. Contact piezoelectric transducers are then used to excite the samples at ultrasonicfrequencies. The thermal responses of the crystals are recorded using infrared thermography, and the rate of heating is estimated. Surface temperature increases up to 15 °C …

Generalized Techniques For Using System Execution Traces To Support Software Performance Analysis, Thelge Manjula Peiris

Open Access Dissertations

This dissertation proposes generalized techniques to support software performance analysis using system execution traces in the absence of software development artifacts such as source code. The proposed techniques do not require modifications to the source code, or to the software binaries, for the purpose of software analysis (non-intrusive). The proposed techniques are also not tightly coupled to the architecture specific details of the system being analyzed. This dissertation extends the current techniques of using system execution traces to evaluate software performance properties, such as response times, service times. The dissertation also proposes a novel technique to auto-construct a dataflow model …

Estimating The Water Quality Condition Of River And Lake Water In The Midwestern United States From Its Spectral Characteristics, Jing Tan

Open Access Dissertations

This study focuses on developing/calibrating remote sensing algorithms for water quality retrieval in Midwestern rivers and lakes. In the first part of this study, the spectral measurements collected using a hand-held spectrometer as well as water quality observations for the Wabash River and its tributary the Tippecanoe River in Indiana were used to develop empirical models for the retrieval of chlorophyll (chl) and total suspended solids (TSS). A method for removing sky and sun glint from field spectra for turbid inland waters was developed and tested. Empirical models were then developed using a subset of the field measurements with the …

Time Distortion In Bierce's "One Of The Missing" And Uroshevic's "Ракописот Од Китаб-Ан" ("The Manuscript From Kitab-An"), Kalina Maleska

CLCWeb: Comparative Literature and Culture

In her article "Time Distortion in Bierce's 'One of the Missing' and Uroshevic's 'Ракописот од Китаб-Ан' ('The Manuscript from Kitab-An')" Kalina Maleska examines the relationship between literature and astronomy in the context of time. The two stories share several common elements: they explore the possible manipulations of time in unexpected and extraordinary ways and come close to certain scientific explorations of time. For "One of the Missing," Albert Einstein's theory of relativity provides an interesting foundation for understanding Bierce's treatment of time. For The Manuscript of Kitab-An, the speculations of time travel starting from the Einstein-Rosen concept of the black …

Assessing A Monitoring Scale Of Physiological Health And Risk Assessment Among Those Exposed To Heated Environments: A Brief Report, Corey A. Peacock, Ellen L. Glickman, Gabriel J. Sanders, Yong Suk Seo, Brandon S. Pollock, Keith J. Burns, Lynn Kakos, John Gunstad

Journal of Human Performance in Extreme Environments

Background: Prevention of heat illness is of considerable medical interest within the field of occupational work. There are many established methods of perceptual health assessment; however, many are rather unpractical and timely. The objective was to improve the practicality and timeliness of perceptual physiological monitoring; a Heat Thermal Sensation scale has been developed. The usefulness of the scale was assessed on its ability to monitor physiological variable. Materials and Methods: Ten apparently healthy individuals performed physically exerting activity while exposed to 37 °C. Sensation and physiology were measured throughout. Results: The perceptual monitoring scale demonstrated weak positive correlations with human …

Stress Granules Modulate Syk To Cause Microglial Cell Dysfunction In Alzheimer's Disease, Soumira Ghosh, Robert Geahlen

Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications

Microglial cells in the brains of Alzheimer's patients are known to be recruited to amyloid-beta (Aβ) plaques where they exhibit an activated phenotype, but are defective for plaque removal by phagocytosis. In this study, we show that microglia stressed by exposure to sodium arsenite or Aβ(1–42) peptides or fibrils form ex- tensive stress granules (SGs) to which the tyrosine kinase, SYK, is recruited. SYK enhances the formation of SGs, is active within the resulting SGs and stimulates the production of reactive oxygen and nitrogen species that are toxic to neuronal cells. This sequestration of SYK inhibits the ability of microglial …

Analysis Of The Fabrication Conditions In Organic Field-Effect Transistors, Rachel M. Rahn, Yan Zhao, Jianguo Mei

The Summer Undergraduate Research Fellowship (SURF) Symposium

Polymer-based organic field-effect transistors have raised substantial awareness because they enable low-cost, solution processing techniques, and have the potential to be implemented in flexible, disposable organic electronic devices. The performance of these devices is highly dependent on the processing conditions, as well as the intrinsic properties of the polymer. Processing conditions play an important role in semiconductor film formation and device performance. These factors may provide an important link between structure and performance. In this study, an empirical analysis tool, Process Scout, was applied to assess processing factors such as polymer concentration and silicon modification. This sanctioned the creation of …

Studies Of Optical And Electronic Properties Of Nanoparticles For Solar Energy Conversion, Caitlin Kruse, Libai Huang

The Summer Undergraduate Research Fellowship (SURF) Symposium

The higher energy needs for today's technological society requires sustainable and renewable energy source, such as solar energy. This study focuses on using semiconducting quantum dots and fluorescent dyes as light absorbers for solar energy conversion devices such as solar cells. Quantum dots are small nanocrystals (usually 2-10 nm in diameter) with tunable absorbing properties. The smaller the dot, the shorter the wavelength being absorbed. Quantum dots are extremely efficient light absorbers and emitters. Fluorescent dyes have a high quantum yield. In order to examine the energy conversion, cadmium selenide (CdSe) quantum dots and Rhodamine 6G (R6G) dye were spin …

Effect Of Helium Ions Energy On Molybdenum Surfaces Under Extreme Conditions, Joseph Fiala, Jitendra K. Tripathi, Sean Gonderman, Ahmed Hassanein

The Summer Undergraduate Research Fellowship (SURF) Symposium

Plasma facing components (PFCs) in fusion devices must be able to withstand high temperatures and erosion due to incident energetic ion radiations. Tungsten has become the material of choice for PFCs due to its high strength, thermal conductivity, and low erosion rate. However, its surface deteriorates significantly under helium ion irradiation in fusion-like conditions and forms nanoscopic fiber-like structures, or fuzz. Fuzz is brittle in nature and has relatively lower thermal conductivity than that of the bulk material. Small amounts of fuzz may lead to excessive contamination of the plasma, preventing the fusion reaction from taking place. Despite recent efforts, …

Implementation Of A Speech Recognition Algorithm To Facilitate Verbal Commands For Visual Analytics Law Enforcement Toolkit, Shubham S. Rastogi, David L. Wiszowaty, Hanye Xu, Abish Malik, David S. Ebert

The Summer Undergraduate Research Fellowship (SURF) Symposium

The VALET (Visual Analytics Law Enforcement Toolkit) system allows the user to visualize and predict crime hotspots and analyze crime data. Police officers have difficulty in using VALET in a mobile situation, since the system allows only conventional input interfaces (keyboard and mouse). This research focuses on introducing a new input interface to VALET in the form of speech recognition, which allows the user to interact with the software without losing functionality. First an Application Program Interface (API) that was compatible with the VALET system was found and initial code scripts to test its functionality were written. Next, the code …

Development Of A Scalable Synthesis Of Hp-Β-Cd Pluronic Polyrotaxanes, Joseph L. Skulsky, Elizabeth A. Slepko, Bradley P. Loren, David H. Thompson

The Summer Undergraduate Research Fellowship (SURF) Symposium

Polyrotaxanes are polymers that have macrocycles threaded onto them, analogous to beads threaded onto a string. These materials are used for a variety of different biomedical applications.^1-3 The Thompson group has been developing 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) polyrotaxanes as therapeutics for the treatment of Niemann-Pick Type C (NPC) disease. NPC is a debilitating genetic disorder where cholesterol accumulates in the lysosomes of cells.⁴ Developing a scalable process is crucial for the advancement of these materials as NPC therapeutics. The goal of this project is to optimize the only protocol for the synthesis of HP-β-CD/Pluronic polyrotaxanes in order to develop a …

Using Dissipative Particle Dynamics For Modeling Surfactants, Yuchen Zhang, Arezoo M. Ardekani

The Summer Undergraduate Research Fellowship (SURF) Symposium

Oil recovery is an industrial process that injects aqueous solutions into an oil reservoir to pump out crude oil and promote the oil production. The aqueous solution contains surfactants for reducing the interfacial tension (IFT) between aqueous phase and oil. The critical micelle concentration (CMC) is the concentration of surfactant above which micelles form and the interfacial tension reaches a plateau. Our research seeks to measure IFT and CMC for surfactants using dissipative particle dynamics (DPD) technique, which is a coarse-grained method based on the molecular dynamics. We first study how IFT is influenced by the surfactant concentration. Furthermore, another …

Optical Emission Spectroscopy Diagnostics Of Cold Plasmas For Food Sterilization, Abhijit Jassem, Michael Lauria, Russell Brayfield Ii, Kevin M. Keener, Allen L. Garner

The Summer Undergraduate Research Fellowship (SURF) Symposium

There is a growing need for economical, effective, and safe methods of sterilizing fresh produce. The most common method is a chlorine wash, which is expensive and may introduce carcinogens. High voltage cold atmospheric pressure plasmas are a promising solution that has demonstrated a germicidal effect; however, the responsible chemical mechanisms and reaction pathways are not fully understood. To elucidate this chemistry, we used optical emission spectroscopy to measure the species produced in the plasma generated by a 60 Hz pulsed dielectric barrier discharge in a plastic box containing various fill gases (He, N₂, CO₂, dry …

Web-Based Fragment Library, Junjie Wang, Lyudmila Slipchenko

The Summer Undergraduate Research Fellowship (SURF) Symposium

A new polarized force field BioEFP for modeling process in biology is far superior in accuracy to the common classical force fields. One of the main shortcomings of BioEFP is that the parameters are not readily available, thus it will take a lot of time to be calculated.

Developing an online repository of pre-computed fragment parameters and a similarity algorithm will allow ascribing each fragment of a biological macromolecule to a pre-defined fragment.

This study incorporates three parts to create the online repository. First, the visual design for the website using the Hypertext Markup Language and the Cascading Style Sheets …

Classification And Visualization Of Crime-Related Tweets, Ransen Niu, Jiawei Zhang, David S. Ebert

The Summer Undergraduate Research Fellowship (SURF) Symposium

Millions of Twitter posts per day can provide an insight to law enforcement officials for improved situational awareness. In this paper, we propose a natural-language-processing (NLP) pipeline towards classification and visualization of crime-related tweets. The work is divided into two parts. First, we collect crime-related tweets by classification. Unlike written text, social media like Twitter includes substantial non-standard tokens or semantics. So we focus on exploring the underlying semantic features of crime-related tweets, including parts-of-speech properties and intention verbs. Then we use these features to train a classification model via Support Vector Machine. The second part is to utilize visual …

Gpu/Cpu Performance Of Image Processing Tasks For Use In The Cam 2 System, Jonathan Cottom, Yung-Hsiang Lu, Young-Sol Koh

The Summer Undergraduate Research Fellowship (SURF) Symposium

Over the past several years, graphics processing units (GPU) have increasingly been viewed as the future of image processing engines. Currently, the Continuous Analysis of Many CAMeras (CAM²) project performs its processing on CPUs, which will potentially be more costly as the system scales to service more users. This study seeks to analyze the performance gains of GPU processing and evaluate the advantage of supporting GPU-accelerated analysis for CAM² users. The platform for comparing the CPU and GPU performance has been the NVIDIA Jetson TK1. The target hardware implementation is an Amazon cloud instance, where final cost …

Kinetic Modeling Of Roll To Roll Rfcvd Plasma, Kudzo S. Ahegbebu, Siva Sashank Tholeti, Alina A. Alexeenko

The Summer Undergraduate Research Fellowship (SURF) Symposium

Roll-to-roll radio frequency plasma enhanced chemical vapor deposition (R2R RFCVD) is a technique for large-scale synthesis of high quality graphitic nanopetals. Graphitic nanopetals are petal-like graphene structures with remarkable electrical and mechanical properties with major industrial applications such as microsupercapacitors. RFCVD uses a non-equilibrium plasma with high energy electrons to catalyze chemical reactions, induce the creation of free radicals, and promote otherwise high temperature chemistry in a low temperature environment. Understanding how bulk plasma characteristics (particularly, power and number densities) vary with changing reactor parameters is an important step towards optimizing synthesis techniques. In our present work we use the …

Dsmc Simulation Of Microstructure Actuation By Knudsen Thermal Force, Aaron Pikus, Israel Sebastiao, Andrew Strongrich, Alina Alexeenko

The Summer Undergraduate Research Fellowship (SURF) Symposium

In many industrial and research applications there is a need for vacuum sensors with higher accuracy and spatial resolution than what is currently available. Examples of target applications include high-altitude platforms, satellites and in-vacuum manufacturing processes such as freeze-drying of food and pharmaceuticals. In this connection, a novel pressure sensor, named Microelectromechanical In-plane Knudsen Radiometric Actuator (MIKRA), has been developed by at Purdue University. MIKRA is based on Knudsen thermal forces generated by rarefied flow driven by thermal gradients within the microstructure Thus, the goal of this work is to model the rarefied gas flow in the MIKRA sensor under …

Bio-Inspired Composite Hydrogels For Osteochondral Regenerative Engineering, Grant N. Gellert, Liangju Kuang, Chunhui Jiang, Nur P. Damayanti, Joseph Irudayaraj, Meng Deng

The Summer Undergraduate Research Fellowship (SURF) Symposium

Treatment of osteochondral defects encompassing injury or degeneration to both the articular cartilage as well as the underlying subchondral bone presents a significant medical challenge. Current treatment options including autografts and allografts suffer from limited availability and risk of immunogenicity, respectively. The long term goal of this work is to develop an integrated scaffold system for treatment of osteochondral defects via in situ regeneration of bone, cartilage and the bone-cartilage interface. Hydrogels composed of polymer networks swollen in water provide an attractive biomaterial platform for regeneration of cartilage. In the present study, we have developed a novel composite hydrogel consisting …

Synthesis, Characterization, And Thermoelectric Properties Of Radical Siloxanes, Arnold J. Eng, Bryan Boudouris, Edward P. Tomlinson, Martha Emily Hay

The Summer Undergraduate Research Fellowship (SURF) Symposium

More than half of the annual energy consumption in the United States is lost as waste heat. Polymer-based thermoelectric devices have the potential to utilize this waste heat both sustainably and cost-effectively. Although conjugated polymers currently dominate research in organic thermoelectrics, the potential of using polymers with radical pendant groups have yet to be realized. These polymers have been found to be as conductive as pristine (i.e., not doped) poly(3-hexylthiophene) (P3HT), a commonly-used charge-transporting conjugated polymer. This could yield promising avenues for thermoelectric material design as radical polymers are more synthetically tunable and are hypothesized to have a high Seebeck …