Physical Sciences and Mathematics Commons^™

Radiomic Features To Predict Overall Survival Time For Patients With Glioblastoma Brain Tumors Based On Machine Learning And Deep Learning Methods, Lina Chato

UNLV Theses, Dissertations, Professional Papers, and Capstones

Machine Learning (ML) methods including Deep Learning (DL) Methods have been employed in the medical field to improve diagnosis process and patient’s prognosis outcomes. Glioblastoma multiforme is an extremely aggressive Glioma brain tumor that has a poor survival rate. Understanding the behavior of the Glioblastoma brain tumor is still uncertain and some factors are still unrecognized. In fact, the tumor behavior is important to decide a proper treatment plan and to improve a patient’s health. The aim of this dissertation is to develop a Computer-Aided-Diagnosis system (CADiag) based on ML/DL methods to automatically estimate the Overall Survival Time (OST) for …

Dust-Gas Dynamics Driven By The Streaming Instability With Various Pressure Gradients, Stanley Antedio Baronett

UNLV Theses, Dissertations, Professional Papers, and Capstones

The radial pressure gradient (RPG), along the midplane of gaseous protoplanetary disks (PPD) – planetary nurseries – poses a severe obstacle to planet formation. Micron-sized dust grains, embedded in the disc, must quickly grow to kilometer-sized planetesimals – the building blocks of planets – before fatally drifting inwards, by RPG-induced gas drag, into a central host star. However, the RPG simultaneously powers one of the most robust processes to overcome this radial-drift barrier: the streaming instability (SI). Spontaneously triggered, the SI aerodynamically concentrates drifting dust via drag-induced, coupled interactions and feedback with the surrounding gas. In particular, the non-linear phase …

The Effects Of Winds On Accretion Disks And Spectra Of X-Ray Binaries And Active Galactic Nuclei, Shalini Ganguly

UNLV Theses, Dissertations, Professional Papers, and Capstones

Active galactic nuclei (AGNs) and X-ray binaries (XRBs) contain at their cores supermassive black holes (SMBH), and stellar mass black holes or neutron stars, respectively. These objects bind matter gravitationally, leading to the formation of accretion disks. The accretion of matter leads to efficient conversion of gravitational potential energy into radiation. When the force and/or energy imparted by this radiation on matter exceeds the attractive force due to the local gravitational field, it leads to the launching of matter in the form of outflows or winds. These outflows produce blueshifted (and occasionally redshifted) emission or absorption components in the spectra …

The Dissolution And Recovery Of Critical Materials (Li2co3 And Uf6) From Ionic Liquid, Cassara Higgins

UNLV Theses, Dissertations, Professional Papers, and Capstones

Lithium and uranium are critical materials in both the energy industry and for national security. Lithium is necessary for the next generation of batteries and 6Li is valuable for the production of tritium necessary for both fusion energy and to maintain our nuclear stockpiles. Uranium is a fuel source or precursor fuel source for commercially operating nuclear fission power. The monitoring of uranium hexafluoride (UF6) enrichment at foreign facilities is important for the monitoring of nuclear safeguards and enforcement of non-proliferation treaties. Recovery methods for lithium at the end of life of batteries are necessary to ensure abundance of the …

Positive Solutions To Semilinear Elliptic Equations With Logistic-Type Nonlinearities And Harvesting In Exterior Domains, Eric Jameson

UNLV Theses, Dissertations, Professional Papers, and Capstones

Existing results provide the existence of positive solutions to a class of semilinear elliptic PDEs with logistic-type nonlinearities and harvesting terms both in RN and in bounded domains U ⊂ RN with N ≥ 3, when the carrying capacity of the environment is not constant. We consider these same equations in the exterior domain Ω, defined as the complement of the closed unit ball in RN , N ≥ 3, now with a Dirichlet boundary condition. We first show that the existing techniques forsolving these equations in the whole space RN can be applied to the exterior domain with some …

Revisiting The Chemistry Of Uranium And Rhenium Fluorides: Implication To Fuel Cycle And Nuclear Forensics Science, James Amos-Aimé Louis-Jean

UNLV Theses, Dissertations, Professional Papers, and Capstones

Fluorine plays a major role in the nuclear industry where F2(g) and HF(g) are critical to the preparation of UF6 and UF4. These materials are prepared for uranium enrichment to increase the isotopic concentration of 235U. During separation efforts, the isotope 99Tc (a high yield fission product, 6.1% from 235U) is extracted along with uranium and can be converted to binary technetium fluorides (i.e., TcF4, TcF6) during re-enrichment of used uranium material. This provides a route for 99Tc to reenter the reactor environment and affect the nuclear properties of fuel pellets made with reprocessed uranium. The objective of this work …

Viability Of Energy And Fuel Sources For Interstellar Travel; Design And Feasibility Of The Construction Of Manned Interstellar Space Shuttles, Lukas Mittelman

UNLV Theses, Dissertations, Professional Papers, and Capstones

The importance of proving the viability of interstellar transport and addressing its potential hazards and pitfalls is immense. If we do not look toward the future and examine what could be waiting for us, we are doing our children, our children’s children, and so on, a disservice. Here we must attempt to lay the groundwork for our future scientists, engineers, and adventurers. Asking and answering questions like, which propulsion and energy systems must we incorporate to send us through the cosmos? Will we utilize technologies known today, such as fossil fuel rockets, fission or fusion rockets, and antimatter drives (pion …

A Survey Of The Br´Ezis-Nirenberg Problem And Related Theorems, Edward Huynh

UNLV Theses, Dissertations, Professional Papers, and Capstones

Nonlinear elliptic partial differential equations on bounded domains arise in several different areas of mathematics that include geometry, mathematical physics, and the calculus of variations. The Br ́ezis-Nirenberg problem is concerned with a boundary-value problem that is intimately connected to the existence of positive solutions of the Yamabe problem, of non-minimal solutions to Yang-Mills functionals, and of extremal functions to several important inequalities. Results on existence and uniqueness have been obtained in cases when the exponent is sub-critical, but such results have not been obtained when the exponent is critical due to a lack of compactness. The earliest results obtained …

An Empirical Investigation Into The Impact Of Automated Grading, Alex James St. Aubin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Context: Computer Science enrollment has seen increases in recent years. At the University of Nevada, Las Vegas we have seen an average year to year growth rate of 17.33% in the spring and 13.71% in the fall over the past 10 years in our entry level programming course. These enrollment increases have led to considerable additional costs for grading course material.Objective: The goal of this study is to determine the impact of automatic grading systems on students. If automatic grading is at least as effective as manual grading in practice, it may reduce cost under the context of at least …

Miocene Ichnofaunas And Mammalian Communities In The Great Basin Region, Nevada And California, Annmarie R. Jones

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of this dissertation is to document and interpret three new ichnofaunas and two fossil assemblages from the Neogene of Nevada and California. Ichnofossils are important for understanding behavior and geographical range of animals in the distant past and are key to locating and preserving sensitive material for future studies. I examined ichnofauna at three localities: two within the Mio-Pliocene Muddy Creek Formation of Nevada, and one within the Miocene China Ranch Beds of California. My research focuses primarily on (1) camelid and ursid ichnotaxa and how these new localities help in understanding the evolutionary history of these taxa …

Effects Of Distributed Energy Resources On The Bulk Electric System, Stryder Loveday

UNLV Theses, Dissertations, Professional Papers, and Capstones

The traditional power grid was designed with a centralized resource distribution in mind, with a relatively small number of large power generation facilities supplying the vast majority of load. With recent efforts to further diversify the power grid as well as an increased interest in renewable energy sources, there has been an unprecedented amount of new DistributedEnergy Resources (DERs) added to the grid within the last decade. This often heavily influences the local demand where these resources are installed, often causing power to flow in ways not anticipated by the original design of the grid. This thesis reviews the potential …

Dispersion In High Temperature Superconductors, Lazar Novakovic

Undergraduate Research Symposium Podium Presentations

Superconductors are used in many different industries: Efficient power transmission, Maglev train, MRIs

Expanding The Library Of Planet Building Materials In Magrathea, Rosalie Chaleunsouck, Tristan Benally

Undergraduate Research Symposium Posters

Exoplanets are often modeled with fully-differentiated layers of iron, silicates, water, and gas. The large pressure and temperature ranges within each layer results in changes of phase and mineral equilibrium. MAGRATHEA is an open-course planet interior structure code with a large library of equations of state for planet building materials. This allows for the user to build detailed planet models and test differing measurements of the equation of state. We extend MAGRATHEA's library to include upper-mantle materials and various phases of iron cores. We show the impact of these materials on the characterization of rocky planet interiors.

Microbial Life In Deep-Subsurface Environments: The Role Of High Pressure In Biogeochemical Cycles, Cheyenne Brokaw

Undergraduate Research Symposium Posters

Ocean World: An ocean world is considered any planet or moon currently with a liquid ocean. While the deepest part of the Ocean (Mariana Trench, 11,000 mbsl, 110 Mpa) and the lithosphere host microbial life, it begs the question, How?

Low-Cost Adsorbent For Disinfection Byproduct Removal From Drinking Water, Savanna Vacek, Suraj Pochampally

Undergraduate Research Symposium Posters

Disinfection byproducts (DBPs) are harmful contaminants that are unintentionally created in disinfected water after chlorination. Activated carbon, often expensive and difficult to acquire in low-income and rural areas, has previously been used to remove DBPs from drinking water. Biochar is made from agricultural waste (i.e. feedstock) and has been identified as a low-cost yet effective adsorbent to remote contaminants from drinking water. This work focuses on the efficacy of biochar and activated carbon to remove DBPs from drinking water for the purpose of treating drinking water after emergency chlorination. This study has the potential to help water distributors and disadvantaged …

Identification Of Lipid Species: Potential Biomarkers For Early Detection Of Hepatocellular Carcinoma, Kit Yee Leung, Kaylee Freitas

Undergraduate Research Symposium Posters

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HCC is associated with cirrhosis. Poor survival rate of HCC is due to diagnosis of HCC at late stage.

Powering A Sustainable Electric Vehicle Future, Harmony Ruth, Jordan Brickman

Undergraduate Research Symposium Posters

Electric vehicle sales account for roughly 20% of total sales world wide and are projected to be 80% by 2050. China's electric vehicle market holds a 13.3% market share. China exported 550,000 electric vehicles in 2021. China represents a 54% share of the world's coal consumption as of 2020. Why study China on this issue? China is a major player in the World Economy.

Synthesis Of Modified Walnut Shell Biochar And Material Characterization In Ground Water Treatment, Maaike Parajes, Suraj Pochampally

Undergraduate Research Symposium Posters

Biochar (BC) is a carbon-rich material synthesized from the pyrolysis of biomasses and developed to remove soil and wastewater contaminants. The pyrolysis process involves thermally decomposing the organic materials in the absence of oxygen. Biochar has the potential to be an eco-friendly and effective adsorbent for heavy metals and toxic organic compounds. An adsorbent is a material that attracts other substances on its surface, chemically and physically. Walnut shells were chosen for the biochar modification to improve the surface morphology, pore structure, and adsorption capability.

Biochar Hydrophilicity Characterization By A Smartphone-Based Apparatus: Design, Construction, And Measurement Calibration, Emma Letourneau, Suraj Pochampally

Undergraduate Research Symposium Posters

Water contact angles are used to determine hydrophilicity, which is a material's attraction to water. A water contact angle of greater than 90 degrees indicates a hydrophobic material that repels water, whereas a contact angle of less than 90 degrees indicates a hydrophilic material [Fig. 1]. Water contact angles are measured through a goniometer, which can cost between $2000 to $10,000.

Biochar is a porous carbon material created from biological waste products, that is pyrolyzed (i.e. burned) in a low-oxygen, high heat environment. Biochar can be used to remove contaminants from water and remediate soil while reusing waste, making it …

Climate Change Hope Scale: Factor Analysis In An Adult Sample, Gemma Ortega, Steven J. Glover, Jesse Tabaczynksi, Orei Z. Odents

Undergraduate Research Symposium Posters

Willpower - how much individuals believe that set goals can be met. Waypower - the extent to which individuals can think of strategies for accomplishing those goals.

The Climate Change Hope Scale (CCHS; Li & Monroe, 2017) was designed to measure three aspects of hope: 1. Personal sphere willpower and waypower (WP) 2. Collective sphere willpower and waypower (CW) 3. Lack of willpower and waypower (LW).

A three-factor model fits the CCHS among adolescents. The purpose of our study was to determine if the three-factor model fits the CCHS in adults.

Quantification Of Organic Carbon Sequestered By Biogenic Iron Sulfide Minerals In Long-Term Anoxic Laboratory Incubations, Nader Nabeh, Cheyenne Brokaw, Aude Picard

Life Sciences Faculty Research

Organic carbon sequestration in sedimentary environments controls oxygen and carbon dioxide concentrations in the atmosphere. While minerals play an important role in the preservation of organic carbon, there is a lack of understanding about the formation and stability of organo-mineral interactions in anoxic environments, especially those involving authigenic iron sulfide minerals. In this study, we quantified organic carbon and nitrogen sequestered in biogenic iron sulfide minerals co-precipitated with sulfate-reducing bacteria (SRB) in freshwater and marine conditions in long-term laboratory experiments. The amounts of C and N associated with biogenic iron sulfide minerals increased with increasing cell biomass concentrations available in …

Artificial Intelligence Framework Identifies Candidate Targets For Drug Repurposing In Alzheimer’S Disease, Jiansong Fang, Pengyue Zhang, Quan Wang, Chien Wei Chiang, Yadi Zhou, Yuan Hou, Jielin Xu, Rui Chen, Bin Zhang, Stephen J. Lewis, James B. Leverenz, Andrew A. Pieper, Bingshan Li, Lang Li, Jeffrey Cummings, Feixiong Cheng

Brain Health Faculty Research

Background: Genome-wide association studies (GWAS) have identified numerous susceptibility loci for Alzheimer’s disease (AD). However, utilizing GWAS and multi-omics data to identify high-confidence AD risk genes (ARGs) and druggable targets that can guide development of new therapeutics for patients suffering from AD has heretofore not been successful. Methods: To address this critical problem in the field, we have developed a network-based artificial intelligence framework that is capable of integrating multi-omics data along with human protein–protein interactome networks to accurately infer accurate drug targets impacted by GWAS-identified variants to identify new therapeutics. When applied to AD, this approach integrates GWAS findings, …

Evaluation Of Continuous Power-Down Schemes, James Andro-Vasko, Wolfgang Bein

Computer Science Faculty Research

We consider a power-down system with two states—“on” and “off”—and a continuous set of power states. The system has to respond to requests for service in the “on” state and, after service, the system can power off or switch to any of the intermediate power-saving states. The choice of states determines the cost to power on for subsequent requests. The protocol for requests is “online”, which means that the decision as to which intermediate state (or the off-state) the system will switch has to be made without knowledge of future requests. We model a linear and a non-linear system, and …

Novel Architecture Of Onem2m-Based Convergence Platform For Mixed Reality And Iot, Seungwoon Lee, Woogeun Kil, Byeong Hee Roh, Si-Jung Kim, Jin Suk Kang

College of Engineering Faculty Research

There have been numerous works proposed to merge augmented reality/mixed reality (AR/MR) and Internet of Things (IoT) in various ways. However, they have focused on their specific target applications and have limitations on interoperability or reusability when utilizing them to different domains or adding other devices to the system. This paper proposes a novel architecture of a convergence platform for AR/MR and IoT systems and services. The proposed architecture adopts the oneM2M IoT standard as the basic framework that converges AR/MR and IoT systems and enables the development of application services used in general-purpose environments without being subordinate to specific …

An Approach For Material Model Identification Of A Composite Coating Using Micro-Indentation And Multi-Scale Simulations, Pouya Shojaei, Riccardo Scazzosi, Mohamed Trabia, Brendan O’Toole, Marco Giglio, Xing Zhang, Yiliang Liao, Andrea Manes

Mechanical Engineering Faculty Research

While deposited thin film coatings can help enhance surface characteristics such as hardness and friction, their effective incorporation in product design is restricted by the limited understand-ing of their mechanical behavior. To address this, an approach combining micro-indentation and meso/micro-scale simulations was proposed. In this approach, micro-indentation testing was conducted on both the coating and the substrate. A meso-scale uniaxial compression finite element model was developed to obtain a material model of the coating. This material model was incorporated within an axisymmetric micro-scale model of the coating to simulate the indentation. The proposed approach was applied to a Ti/SiC metal …

Stability And Mechanical Properties Of W1-X Mox B4.2 (X=0.0-1.0) From First Principles, Weiguang Gong, Rui Xu, Xuecheng Shao, Quan Li, Changfeng Chen

Physics & Astronomy Faculty Research

Heavy transition-metal tetraborides (e.g., tungsten tetraboride, molybdenum tetraboride, and molybdenum-doped tungsten tetraboride) exhibit superior mechanical properties, but solving their complex crystal structures has been a long-standing challenge. Recent experimental x-ray and neutron diffraction measurements combined with first-principles structural searches have identified a complex structure model for tungsten tetraboride that contains a boron trimer as an unusual structural unit with a stoichiometry of 1:4.2. In this paper, we expand the study to binary MoB4.2 and ternary W1-xMoxB4.2 (x=0.0-1.0) compounds to assess their thermodynamic stability and mechanical properties using a tailor-designed crystal structure search method in conjunction with first-principles energetic calculations. Our …

Numerical Modeling Of Mineralizing Processes During The Formation Of The Yangzhuang Kiruna-Type Iron Deposit, Middle And Lower Yangtze River Metallogenic Belt, China: Implications For The Genesis And Longevity Of Kiruna-Type Iron Oxide-Apatite Systems, Xunyu Hu, Simon Jowitt, Feng Yuan, Guangxian Liu, Jinhui Luo, Yuhua Chen, Hui Yang, Keyue Ren, Yongguo Yang

Geoscience Faculty Research

The Yangzhuang iron deposit is a Kiruna-type iron oxide-apatite (IOA) deposit within the Ningwu mining district of the Middle and Lower Yangtze River Metallogenic Belt (MLYRMB), China. This study applies a numerical modeling approach to identify the key processes associated with the formation of the deposit that cannot be easily identified using traditional analytical approaches, including the duration of the mineralizing process and the genesis of iron orebodies within intrusions associated with the deposit. This approach highlights the practical value of numerical modeling in quantitatively analyzing mineralizing processes during the formation of mineral deposits and assesses how these methods can …

Eccentric Neutron Star Disk Driven Type Ii Outburst Pairs In Be/X-Ray Binaries, Alessia Franchini, Rebecca G. Martin

Physics & Astronomy Faculty Research

Be star X-ray binaries are transient systems that show two different types of outbursts. Type I outbursts occur each orbital period while type II outbursts have a period and duration that are not related to any periodicity of the binary system. Type II outbursts may be caused by mass transfer to the neutron star from a highly eccentric Be star disk. A sufficiently misaligned Be star decretion disk undergoes secular Von Zeipel-Lidov-Kozai (ZLK) oscillations of eccentricity and inclination. Observations show that in some systems the type II outbursts come in pairs with the second being of lower luminosity. We use …

Machine Learning And Radiomic Features To Predict Overall Survival Time For Glioblastoma Patients, Lina Chato, Shahram Latifi

Electrical & Computer Engineering Faculty Research

Glioblastoma is an aggressive brain tumor with a low survival rate. Understanding tumor behavior by predicting prognosis outcomes is a crucial factor in deciding a proper treatment plan. In this paper, an automatic overall survival time prediction system (OST) for glioblastoma patients is developed on the basis of radiomic features and machine learning (ML). This system is designed to predict prognosis outcomes by classifying a glioblastoma patient into one of three survival groups: short-term, mid-term, and long-term. To develop the prediction system, a medical dataset based on imaging information from magnetic resonance imaging (MRI) and non-imaging information is used. A …

Data Of The Constructivist Practices In The Learning Environment Survey From Engineering Undergraduates: An Exploratory Factor Analysis, Chengcheng Li, Shaoan Zhang, Tiberio Garza, Yingtao Jiang

Teaching and Learning Faculty Research

This paper presents the dataset of a questionnaire on first-year engineering undergraduates’ perceptions of constructivist practices in the learning environment. The questionnaire with a 5-Likert scale was adapted from previous research. The sample consisted of 293 first-year engineering undergraduates in the southwest region of the United States. The online questionnaire was sent to participants who completed it voluntarily at the end of Fall 2019. A total of 274 of 293 participants completed the questionnaire with a response rate of 93.515%. Exploratory factor analysis was conducted to test the underlying factor structure of the questionnaire, which serves as a good reference …