Physical Sciences and Mathematics Commons^™

Sonogashira Coupling Routes To Ortho-Alkynl-And- Fused-Ring Sydnones, Andrew John Weisner

Browse all Theses and Dissertations

In the present work, suitably functionalized arylsydnones were used to synthesize a variety of ortho-alkynyl sydnones both as potential precursors to novel sydnoquinolines and to provide non-linear optical (NLO) species of interest to Wright-Patterson Air Force Base (WPAFB). The versatile intermediate, 3-(2-(trimethylsilylethynyl)phenyl)sydnone, was prepared in good yield by the coupling of 3-(2-iodophenyl)sydnone with trimethylsilyl acetylene under Sonogashira conditions. From this intermediate, several ortho-alkynyl sydnones were prepared via a one-pot desilylation with tetrabutylammonium fluoride and Sonogashira coupling with para-substituted aryl iodides. In addition, a three-reaction-in-one-pot procedure was developed to access some of these species directly from 3-(2- iodophenyl)-sydnone. Subsequent reaction of …

Urer, The Transcriptional Activator Of The Proteus Mirabilis Urease Gene Cluster, Is Required For Urease Activity And Virulence In Experimental Urinary Tract Infections, Jonathan D. Dattelbaum, C. Virginia Lockatell, David E. Johnson, Harry L.T. Mobley

Chemistry Faculty Publications

Proteus mirabilis, a cause of complicated urinary tract infection, produces urease, an essential virulence factor for this species. UreR, a member of the AraC/XylS family of transcriptional regulators, positively activates expression of the ure gene cluster in the presence of urea. To specifically evaluate the contribution of UreR to urease activity and virulence in the urinary tract, a ureR mutation was introduced into P. mirabilis HI4320 by homologous recombination. The isogenic ureR::aphA mutant, deficient in UreR production, lacked measurable urease activity. Expression was not detected in the UreR-deficient strain by Western blotting with monoclonal antibodies raised against UreD. Urease …

John Russell Bozeman Papers, Zach S. Henderson Library Special Collections

Finding Aids

This collection consists of research materials belonging to Georgia Southern College instructor, John Russell Bozeman. Materials span 1948-1994 and include research files on beach erosion, the ecology of the Georgia barrier islands, and general information on Southeastern ecology and topography.

Find this collection in the University Libraries' catalog.

The Foldings Of A Square To Convex Polyhedra, Rebecca Alexander, Heather Dyson, Joseph O'Rourke

Computer Science: Faculty Publications

The structure of the set of all convex polyhedra foldable from a square is detailed. It is proved that five combinatorially distinct nondegenerate polyhedra, and four different flat polyhedra, are realizable. All the polyhedra are continuously deformable into each other, with the space of polyhedra having the topology of four connected rings.

Double Stranded Dna-Binding Studies Of Potential Rhodium(Ll) Antitumor Complexes, Amity Elizabeth Burr

Honors Theses

In 1952, Dwyer and coworkers began testing a series of metal complexes for potential inhibition of cancer cell proliferation in animals.[l] The complexes tested were unsuitable for such studies due to their high toxicity. Therefore, no further work was done on the project. However, in 1965, Rosenberg and coworkers revisited the possibility of potential metal-based drugs. Serendipitously, they discovered that cis-diamminedichloroplatinum(lI) (cisplatin) inhibits cell division in E. coli.[2] Further studies of this and other platinum compounds revealed inhibition of tumor cell lines sarcoma 180 and leukemia LI2l0 in mice.[l] Cisplatin was approved by the Food and Drug Administration in 1970 …

Synthesis Of Montiporynes A And B, Traci Jenelle Speed

Honors Theses

This thesis reports the first complete synthesis of monriporynes A and B. isomeric diacetylenes that bear α, β unsaturated ketone functionalities. Recently isolated from the stony coral Montipora sp. these compounds are reported to possess in vitro cytotoxic activity against several human solid tumor cells. We have synthesized both isomers in three simple steps. In the first step, l-iodononyne was prepared by reacting 1-nonyne with N-iodosuccinimide and a catalytic amount of silver nitrate. This iodoalkyne was then coupled with propargyl alcohol using copper iodide as the catalyst to give 2,4dodecadiynyl alcohol. Finally, the diacetylenic alcohol was subjected to the Swern …

On The Development Of The Intersection Of A Plane With A Polytope, Joseph O'Rourke

Computer Science: Faculty Publications

Define a “slice” curve as the intersection of a plane with the surface of a polytope, i.e., a convex polyhedron in three dimensions. We prove that a slice curve develops on a plane without self-intersection. The key tool used is a generalization of Cauchy's arm lemma to permit nonconvex “openings” of a planar convex chain.

Ce-Qual-W2: A Two-Dimensional, Laterally Averaged, Hydrodynamic And Water Quality Model, Version 3.1, Thomas M. Cole, Scott A. Wells

Civil and Environmental Engineering Faculty Publications and Presentations

CE-QUAL-W2 is a two-dimensional, longitudinal/vertical, hydrodynamic and water quality model. Because the model assumes lateral homogeneity, it is best suited for relatively long and narrow waterbodies exhibiting longitudinal and vertical water quality gradients. The model has been applied to rivers, lakes, reservoirs, estuaries, and combinations thereof.

The application of CE-QUAL-W2 requires knowledge in the following areas: 1. Hydrodynamics 2. Aquatic biology 3. Aquatic chemistry 4. Numerical methods 5. Computers and FORTRAN coding 6. Statistics 7. Data assembly and reconstruction.

Water quality modeling is in many ways an art requiring not only knowledge in these areas but also experience in their …

Phosphorus Contamination And Storage In Bottom Sediments Of The James River Arm Of Table Rock Lake, Southwest Missouri, Marc R. Owen

MSU Graduate Theses

Eutrophic conditions in the upper James River Arm (JRA) of Table Rock Lake have been linked to phosphorus (P) inputs by wastewater treatment facilities and increasing urban development in the upper James River Basin (3,770 km2). Since the majority of P in aquatic environments is bound to sediments, bottom sediment can function as both a source and sink of P in lake systems. This study evaluates the spatial distribution, physical and chemical characteristics, and storage of sediment-P in the active layer ( < 5cm) of bottom sediments in the JRA. The JRA makes up about 20% of Table Rock Lake’s surface area, contributes about 30% of the inflow, and has the poorest water quality of the entire lake. For this study, grab samples were collected in the main arm and tributary coves at the deepest part of the lake and at several shallow sites along the main arm. Concentrations increase in a down-lake direction in the main arm ranging from 5 to >2000 ppm P. However, water-column P concentrations show a decrease down-lake, indicating that sedimentation is removing P from …

Temporal Analysis Of Floodplain Deposition Using Urban Pollution Stratigraphy, Wilson Creek, Sw Missouri, Kathy A. Shade

MSU Graduate Theses

Alluvial sediments record both hydrologic changes and variations of sediment quality affecting watersheds. This study uses urban pollution signatures as temporal tracers to date alluvial deposits along Wilson Creek located within Wilson’s Creek National Battlefield Park in southwestern Missouri. The creek drains Springfield, the third largest city in the state, which was settled in 1833. This study has three main objectives: (1) review historical documents to develop a pollution history for the watershed; (2) determine if there is a correlation between heavy metal and phosphorus concentrations in sediment cores and the timing of release of those elements into the creek …

The Role Of Physical, Chemical, And Microbial Heterogeneity On The Field-Scale Transport And Attachment Of Bacteria, Brian J. Mailloux, Mark E. Fuller, Tullis C. Onstott, James Hall, Hailiang Dong, Mary F. Deflaun, Sheryl H. Streger, Randi K. Rothmel, Maria Green, Donald J. P. Swift, Jon Radke

OES Faculty Publications

A field-scale bacterial transport experiment was conducted at the Narrow Channel Focus Area of the South Oyster field site located in Oyster, Virginia. The goal of the field experiment was to determine the relative influence of subsurface heterogeneity and microbial population parameters on flow direction, velocity, and attachment of bacteria at the field scale. The field results were compared with results from laboratory-scale column experiments to develop a method for predicting field-scale bacterial transport. The field site is a shallow, sandy, unconfined, aerobic aquifer that has been characterized by geophysical, sedimentological, and hydrogeological methods. Comamonas sp. strain DA001 and a …

Academic Fleet Renewal- Two Years Later, Larry Atkinson

CCPO Publications

(First paragraph) In November 2000, I wrote a Soapbox article on fleet renewal for Sea Technology. It is a little unsettling to see how slowly ideas move towards implementation. Nevertheless, we are making progress. In this editorial I will note a bit of that progress and try to guess where we will be in two more years.

Observations Of Cross Channel Structure Of Flow In An Energetic Tidal Channel, Mario Caceres, Arnoldo Valle-Levinson, Larry P. Atkinson

CCPO Publications

[1] Measurements of velocity and density profiles were made to describe the transverse structure of flow in Chacao Channel, Southern Chile (41.75 degreesS), where typical tidal velocities are similar to4 m/s. Current profiles were obtained with a 307.2 kHz Acoustic Doppler Current Profiler (ADCP) over 25 repetitions of a cross-channel transect during one semidiurnal tidal cycle. The 2.2 km long transect ran northeast/southwest across the channel. A northern channel (120 m deep) and a southern channel (85 m deep) were separated by Remolinos Rock, a pinnacle that rises to 20 m depth at similar to0.7 km from the southern side. …

Soil Survey Of Grand Staircase- Escalante National Monument Area, Parts Of Kane And Garfield Counties, Utah, United States Department Of Agriculture, Natural Resources Conservation Service

All U.S. Government Documents (Utah Regional Depository)

This soil survey contains information that affects land use planning in this survey area. It contains predictions of soil behavior for selected land uses. The survey also highlights soil limitations, improvements needed to overcome the limitations and the impact of selected land uses on the environment. This soil survey is designed for many different users. Farmers, ranchers, foresters and agronomists can use it to evaluate the potential of the soil and the management needed for maximum food and fiber production. Planners, community officials, engineers, developers, builders and home buyers can use the survey to plan land use, select sites for …

The Utah Trails Initiative: Partnerships, Research, And Action, Steven W. Burr, Dale J. Blahna, Douglas K. Reiter, Michael Butkus

All U.S. Government Documents (Utah Regional Depository)

As a result of changing social values regarding the development and use of our natural resources, more and more emphasis is being placed on the vale of amenity resources, concerning scenery and aesthetics, opportunities for a diversity of recreation experiences, providing habitat for wildlife, and preserving biological diversity (Burr & Blahna, 2000; Siehl, 1990). Many people enjoy a variety of trail-based activities as a source of their recreation. With all their attributes and varieties of usage, trails and pathways are high priorities for many people, including the citizens of Utah. Trails provide access to Utah's outstanding public lands, opportunities for …

Land Health Assessment For The Colorado Canyons National Conservation Area, U.S. Department Of The Interior, Bureau Of Land Management, Grand Junction Field Office, Grand Junction, Colorado

All U.S. Government Documents (Utah Regional Depository)

The Colorado Canyons National Conservation Area (CCNCA) is located about 7 miles west of Grand Junction, Colorado. The CCNCA includes rolling saltbush-covered hills, pinyon-junpier and sagebrush-covered mesas, a 24-mile corridor along the Colorado River through Horsethief and Ruby Canyons, and over 70,000 acres of sheer-sided, red-rock canyons, natural arches, caves and alcoves. The 75,550-acre Black Ridge Canyons Wilderness comprises the heart of the CCNCA, with another 5,200 acres stretching into Utah.

The CCNCA was given a high priority for land health assessment, a valuable tool in developing the CCNCA Resource Management Plan (RMP).

An Architectural Pattern For Adaptable Middleware Infrastructure, Jason J. Mitchell

UNF Graduate Theses and Dissertations

Middleware technologies change so rapidly that designers must adapt existing software architectures to incorporate new emerging ones. This project proposes an architectural pattern and guidelines to abstract the communication barrier whereby allowing the developer to concentrate on the application logic.

We demonstrate our approach and the feasibility of easily upgrading the middleware infrastructure by implementing a sample project and three case studies using three different middlewares on the .NET framework.

Comparison Of Javaspace And Corba Technologies, Anjani Kumar Jha

UNF Graduate Theses and Dissertations

With computer industry increasingly moving towards network-centric systems, particularly the Internet, competing technologies that help design and develop such systems are fast emerging in the marketplace. The fundamental characteristics of a networked environment are heterogeneity, partial failure, latency and difficulty of "gluing together" multiple, independent processes into a robust, scalable application. JavaSpaces, a shared memory paradigm, provides high-level coordination mechanism for Java easing the burden of creating distributed systems. Large class of distributed problems can be approached using Javaspaces' simple framework. JavaSpaces allows processes to communicate even if each was wholly ignorant of the others. CORBA on the other hand …

Development Of An Expert System Tool For Environmental Impact Assessment, Raed Mohamed M. Al Marzouqi

Theses

In this study, approaches to environmental impact assessment are reviewed and discussed. An expert system tool has been developed via the use of Microsoft Access tool for data management and Visual Basic programming for decision-making. Policies and regulations included in the program are based on the Technical Guidelines # 4 of the Dubai Municipality. The salient features of the program can be summarized as follows: the program allows the EIA applicant to input all the necessary information about his/her company and its activities. All discharges to air, water and land are compared with TG # 4 and status report is …

Deuterium Nmr Studies Of Bulk And Silica-Absorbed Polystyrene, Macduff O. Okuom, Jinhua Yang, Frank D. Blum

Chemistry Faculty Research & Creative Works

Thin polymer films are used in applications such as electronics, biomedical devices and coatings. As the trend to make the devices smaller continues, a film's influence on a material's overall properties becomes more prominent. Previous studies have shown that thin polymer films have characteristics slightly different from those of bulk polymers. Film behavior has been characterized by examining thermal expansion, diffusion, conformation, density and glass transitions. The dynamics of glassy polystyrene has been investigated using a wide variety of theoretical and experimental methods. Schaefer et al., using 13C NMR, reported that ~7% of phenyl rings in polystyrene undergo -flips. Using …

Molecular Mass And Dynamics In Pma-D₃ In The Glass Transition Region, Burak Metin, Frank D. Blum

Chemistry Faculty Research & Creative Works

The segmental dynamics through the glass transition region, by which the glassy polymer becomes rubbery, are not well understood. Free volume, thermodynamic and kinetic theories have been used to describe the phenomenon behind the glass transition and some of those theories were tested with computer simulations. Different experimental techniques, such as NMR, thermo-mechanical analysis (TMA), differential scanning calorimetry (DSC), dilatometry and dynamic mechanical analysis (DMA) have all been also used to probe this important phenomena. Deuterium (2H) NMR has been a valuable tool for the investigation of the dynamics of macromolecules. Deuteration of macromolecules at specific locations on the chains …

Ray Tracing And Global Illumination, Jason Rupard

All Volumes (2001-2008)

In order to represent real-world images with a computer, a program has to relate three-dimensional images on a two-dimensional monitor screen. Several ways of doing this exist with varying degrees of realism. One of the most successful methods can be grouped in a "screen-to-world method" of viewing, which is also known as "ray-tracing."
This computer graphics technology simulates light rays within a 3D environment. Since light rays have predictable physical properties, the raytracing algorithm can attempt to calculate the exact coloring of each ray/object intersection at any given pixel. Advanced levels of ray tracing allow light rays to bounce from …

Soil Solution Dynamics In Response To Elevated Nitrogen And Sulfur Treatments At The Bear Brook Watershed In Maine, Johanna Szillery

Electronic Theses and Dissertations

Base cation depletion in forest soils of northeastern North America is a continuing concern because of the ongoing elevated deposition of sulfur (S) and nitrogen (N), intensive-management practices, and the often poorly understood implications of land-use history on modem ecosystem function. At the Bear Brook Watershed in Maine (BBWM), one of two paired, forested watersheds has been subjected to experimental additions of S and N for over a decade. Treatments consist of 28.8 kg S ha-' yr-' and 25.2 kg N ha-' yr-' in the form of granular (NH&SO4 applied bimonthly by helicopter. Ceramic cup tension lysimeters were used to …

12,000-Year Record Of Lake-Level And Vegetative Change At Mathews Pond, Piscataquis County, Maine, Usa, Andrea Masterman Nurse

Electronic Theses and Dissertations

This study of late-glacial and Holocene changes in lake-level and vegetation at Mathews Pond contributes new information about Holocene environments in northeastern North America. The research establishes a 12,000-year record of paleohydrology for the watershed adjacent to Big Reed Forest Reserve, the largest stand of old-growth forest in the northeastern United States. Mathews Pond is a 7.4 ha, closed-basin, groundwaterseepage lake located in an upland, forested region of the Aroostook River drainage system. Glacial meltwater briefly filled the basin - 13.0 ka (1 ka = 1000 I4C yr BP)). The lake existed as a shallow pool in the deep area …

An Information Theoretic Study Of The Ising Antiferromagnet With Quenched Dilution On A Triangular Lattice, Matthew D. Robinson

Electronic Theses and Dissertations

This investigation applies information theoretic techniques to study the ordering and structure of the Ising antiferromagnet with quenched disorder on a triangular lattice. The pure system shows no phase transition due to the high degree of frustration present. However, when quenched vacancies are introduced randomly into this geometrically frustrated system, a phase transition at finite temperature, to an ordered phase, can arise. If the vacancies are introduced on all three sublattices of the triangular lattice, then a two-dimensional spin-glass transition occurs. If dilution takes place on only one sublattice, then the other two sublattices develop magnetiza- tions below the critical …

Crevassing And Calving Of Glacial Ice, James Patrick Kenneally

Electronic Theses and Dissertations

Calving of ice is a relatively new area of research in the still young field of glaciology. In the short time that calving has been studied, it has been mainly treated as an afterthought, with the predominant mode of thinking being that it will happen so to concern oneself with why is not important. Many studies dealt with observations of calving front positions over time vs. ice velocity in an attempt to quantify the calving rate as the difference between the two, while others have attempted to deduce some empirical relationship between calving rate and variables such as water depth …

Performance Advantages Of Maximum Likelihood Methods In Prbs-Modulated Time-Of-Flight Energy Loss Spectroscopy, Zhongyu Yang

Electronic Theses and Dissertations

This thesis describes the design, experimental performance, and theoretical simulation of a novel time-of-flight analyzer that was integrated into a high resolution electron energy loss spectrometer (TOF-HREELS). First we examined the use of an interleaved comb chopper for chopping a continuous electron beam. Both static and dynamic behaviors were simulated theoretically and measured experimentally, with very good agreement. The finite penetration of the field beyond the plane of the chopper leads to non-ideal chopper response, which is characterized in terms of an "energy corruption" effect and a lead or lag in the time at which the beam responds to the …

Design, Implementation And Assessment Of An Earth Systems Science Course For Secondary Teachers, Jeffery C. Owen

Electronic Theses and Dissertations

In the fall of 2002 the Department of Earth Sciences at the University of Maine piloted an innovative course developed as a core offering for the new Master of Science in Teaching program. A team of four instructors comprised of two Earth Sciences faculty and two science educators developed the course and implemented it with nine students- six in-service teachers and three pre-service teachers. The course addressed multiple needs of secondary teachers through the integration of instruction in curriculum design, pedagogy, assessment, and classroom-level educational research, and earth systems science content. The components of instruction taught in the course included: …

Comparison Of Isoflurane And Sevoflurane For Anesthesia In Beaver, Stewart W. Breck, James S. Gaynor

United States Department of Agriculture Wildlife Services: Staff Publications

We compared the hemodynamic and respiratory effects, recovery time, and cost of two gas inhalants (isoflurane and sevoflurane) for anesthetic induction and maintenance of beaver (Castor canadensis) during surgery to implant radio transmitters in the peritoneal cavity. Heart rate, respiratory rate, relative hemoglobin saturation with oxygen (SpO₂), and body temperature were measured every 5 min for the first 45 min, and arterial blood gas was measured once, 25 min into the anesthetic procedure. Induction for either agent was smooth and rapid. Heart rate and respiratory rate both decreased during the procedure though neither was lower than …

Beaver Population Size Estimation In Mississippi, Seth R. Swafford, Dale L. Nolte, Kris Godwin, Charles A. Sloan, Jeanne Jones

United States Department of Agriculture Wildlife Services: Staff Publications

Methods to better quantify beaver (Castor canadensis) population size need to be developed to assist in the direct control methods being implemented by Wildlife Services. Many state game and fish departments rely on lodge counts, cache counts, or fur harvest reports to estimate a station-wide or regional population of beaver. However, Wildlife Services is concerned with estimating population size on a per site basis to assist in estimating project costs and to minimize the number of non-target captures. Six sites in Mississippi were selected to test various methods of population estimation. Various methods included indexing population size based …