Physical Sciences and Mathematics Commons^™

Practical Strengthening Of Preconditions, Ashish Kundu, Patrick Eugster

Department of Computer Science Technical Reports

No abstract provided.

Semi-Parametric Inference For The Partial Area Under The Roc Curve, Fangfang Sun

Mathematics Theses

Diagnostic tests are central in the field of modern medicine. One of the main factors for interpreting a diagnostic test is the discriminatory accuracy. For a continuous-scale diagnostic test, the area under the receiver operating characteristic (ROC) curve, AUC, is a useful one-number summary index for the diagnostic accuracy of the test. When only a particular region of the ROC curve would be of interest, the partial AUC (pAUC) is a more appropriate index for the diagnostic accuracy. In this thesis, we develop seven confidence intervals for the pAUC under the semi-parametric models for the diseased and non-diseased populations by …

Reversal In Declining Trend Of Adult Mortality In Many States Of India, 1970-2001: Is It Due To Aids?, Abhaya Indrayan, Ajay Kumar Bansal

COBRA Preprint Series

Objectives: To investigate the reversal in adult mortality trend from declining to rising in some segments of population in India, and to use an indirect demographic method to examine if this increase could be due to AIDS mortality. Also, to estimate the total excess deaths.

Design: Cross-sectional data on age-specific death rate in 5-year age-intervals from 25 to 44 years for the years 1970 to 1998 for rural/urban and male/female segments for each of 16 major states of India obtained from the government reports, and their projections till the year 2001.

Methods: In view of reversal of trend in some …

Do R_{Aa} And R_{Cp} Quantify Nuclear Medium Effects?, Robert Adrian Zaballa

Physics and Astronomy Dissertations

With the use of an incoherent binary nucleon-nucleon collision model of heavy ion collisions for simulating particle production, it is demonstrated that the nuclear modification factors, R_{AA} and R_{CP}, are less than unity for hard scattering in the absence of any nuclear modification effects. The nuclear modification factor R_{dAu} is also shown to approach or exceed unity only if p_T broadening is taken into account. With a simple phenomenological parameter, the mean nucleon energy loss fraction, this model yields particle distributions that are comparable to those of experiment. The nuclear geometry is described by the Glauber model, and particle production …

Computer-Aided Trauma Decision Making Using Machine Learning And Signal Processing, Soo-Yeon Ji

Theses and Dissertations

Over the last 20 years, much work has focused on computer-aided clinical decision support systems due to a rapid increase in the need for management and processing of medical knowledge. Among all fields of medicine, trauma care has the highest need for proper information management due to the high prevalence of complex, life-threatening injuries. In particular, hemorrhage, which is encountered in most traumatic injuries, is a dominant factor in determining survival in both civilian and military settings. This complication can be better managed using a more in-depth analysis of patient information. Trauma physicians must make precise and rapid decisions, while …

Pfisr Nightside Observations Of Naturally Enhanced Ion Acoustic Lines, And Their Relation To Boundary Auroral Features, R. G. Michell, K. A. Lynch, C. J. Heinselman, H. C. Stenbaek-Nielsen

Dartmouth Scholarship

We present results from a coordinated camera and radar study of the auroral ionosphere conducted during March of 2006 from Poker Flat, Alaska. The campaign was conducted to coincide with engineering tests of the first quarter installation of the Poker Flat Incoherent Scatter Radar (PFISR). On 31 March 2006, a moderately intense auroral arc, (~10 kR at 557.7 nm), was located in the local magnetic zenith at Poker Flat. During this event the radar observed 7 distinct periods of abnormally large backscattered power from the F-region. These were only observed in the field-aligned radar beam, and radar spectra from these …

Evaluation Of Striped Bass Stocks In Virginia, Monitoring And Tagging Studies, 2004-2008 Annual Report, 1 September 2007 - 31 September 2008, Philip W. Sadler, John M. Hoenig, Robert E. Harris, Matthew W. Smith, Rebecca J. Wilk, Lydia M. Goins

Reports

This report presents the results of striped bass (Morone saxatilis) tagging and monitoring activities in Virginia during the period 1 September 2007 through 31 August 2008. It includes an assessment of the biological characteristics of striped bass taken from the 2008 spring spawning run, estimates of annual survival and fishing mortality based on annual spring tagging, and the results of the study that documents the prevalence of mycobacterial infections of striped bass in Chesapeake Bay. The information contained in this report is required by the Atlantic States Marine Fisheries Commission and is used to implement a coordinated management plan for …

Quantum Nondemolition Measurement Of Discrete Fock States Of A Nanomechanical Resonator, E. Buks, E. Segev, S. Zaitsev, B. Abdo, M. P. Blencowe

Dartmouth Scholarship

We study theoretically a radio frequency superconducting interference device integrated with a nanomechanical resonator and an LC resonator. By applying adiabatic and rotating-wave approximations, we obtain an effective Hamiltonian that governs the dynamics of the mechanical and LC resonators. Nonlinear terms in this Hamiltonian can be exploited for performing a quantum nondemolition measurement of Fock states of the nanomechanical resonator. We address the feasibility of experimental implementation and show that the nonlinear coupling can be made sufficiently strong to allow the detection of discrete mechanical Fock states.

Finding Recurrent Regions Of Copy Number Variation: A Review, Oscar M. Rueda, Ramon Diaz-Uriarte

Ramon Diaz-Uriarte

Copy number alterations (CNA) in genomic DNA are linked to a variety of human diseases. Although many methods have been developed to analyze data from a single subject, disease-critical genes are more likely to be found in regions that are common or recurrent among diseased subjects. Unfortunately, finding recurrent CNA regions remains a challenge. We review existing methods for the identification of recurrent CNA regions. Methods differ in their working definition of ``recurrent region'', the type of input data, the statistical and computational methods used to identify recurrence, and the biological considerations they incorporate (which play a role in the …

Time Series Forecasting Model For Chinese Future Marketing Price Of Copper And Aluminum, Zhejin Hu

Mathematics Theses

This thesis presents a comparison for modeling and forecasting Chinese futures market of copper and aluminum with single time series and multivariate time series under linear restrictions. For single time series, data transformation for stationary purpose has been tested and performed before ARIMA model was built. For multivariate time series, co-integration rank test has been performed and included before VECM model was built. Based on selected models, the forecasting shows multivariate time series analysis has a better result than single time series, which indicates utilizing the relationships among the series can improve the accuracy of time series forecasting.

The Separated Fringe Packet Survey: Updating Multiplicity Of Solar-Type Stars Within 22 Parsecs, Christopher Donald Farrington

Physics and Astronomy Dissertations

Over the past half century, multiplicity studies have provided a foundation for the theories of stellar formation and evolution through understanding how likely it is that stars form alone or with companions. If spectroscopic orbits are combined with techniques that can determine visual orbits, we can access the most fundamental parameter of stellar evolution, stellar mass. This dissertation is composed of two main sections. The first involves the investigation of the seminal multiplicity study of Duquennoy & Mayor (1991b) which has been the ``gold standard" for solar-type stars for nearly 20 years. Improvements in technology in the intervening years have …

Theory Of Electronic And Optical Properties Of Nanostructures, Prabath Hewageegana

Physics and Astronomy Dissertations

"There is plenty of room at the bottom." This bold and prophetic statement from Nobel laureate Richard Feynman back in 1950s at Cal Tech launched the Nano Age and predicted, quite accurately, the explosion in nanoscience and nanotechnology. Now this is a fast developing area in both science and technology. Many think this would bring the greatest technological revolution in the history of mankind. To understand electronic and optical properties of nanostructures, the following problems have been studied. In particular, intensity of mid-infrared light transmitted through a metallic diffraction grating has been theoretically studied. It has been shown that for …

Recent Extreme Avalanches: Triggered By Climate Change?, Christian Huggel, Jacqueline Caplan-Auerbach, Rick Wessels

Geology Faculty Publications

On 25 September 2008, seismo meters operated by the Alaska Volcano Observatory (AVO) registered strong ground shaking. On the basis of previous experience with such large seismic signals, AVO personnel were able to rapidly identify the seismic event as an avalanche. Two days later, an AVO overflight of Iliamna volcano, near Alaska's Cook Inlet, confirmed that a massive chunk of glacial ice and rock had broken free from its position on the upper flanks of the volcano, generating a massive avalanche that could have buried an entire town had it occurred in a more populated area.

Rapidly moving rock, ice, …

Potential Driven Deposition Of Poly(Diallyldimethylammonium Chloride) Onto The Surface Of 3-Mercaptopropionic Acid Monolayers Assembled On Gold, Wesley Sanders, Mark Anderson

Mark R. Anderson

Electrochemical impedance spectroscopy (EIS) and quartz crystal microbalance (QCM) measurements are used to examine the ability of applied potential to drive the ionic self-assembly of poly(diallyldimethylammonium) chloride (PDDA) onto a substrate modified with a monolayer of 3-mercaptopropionic acid (3-MPA). The potential of zero charge (PZC) of the gold electrode modified with a monolayer of 3-MPA was found by differential capacitance measurements to be −0.12 (±0.01) V versus Ag−AgCl. Changing the substrate potential to values positive (−0.01 V vs Ag−AgCl) of the PZC induces interfacial conditions that are favorable for the electrostatic deposition of cationic polymers onto the surface of 3-MPA …

The Role Of Science And Engineering In Water Regulation Over The Past 100 Years, James R. May, Patrick Clary

James R. May

This article explores how scientific and engineering principles are inexorably linked to the regulation of water. Scientists and engineers first discovered the link between disease and water sources in the mid-19th century. Over the years, scientists and engineers have led the way to identifying water quality problems and their causes. These discoveries have directly contributed to the scope of water regulation in the United States and elsewhere. In addition, changes in water quality regulation have dictated the need for increasingly sophisticated water treatment technologies and engineers have been at the forefront of the development of these water control technologies. This …

Short-Wave Infrared Diffuse Reflectance Of Textile Materials, Terence Haran

Physics and Astronomy Theses

This thesis analyzes the reflectance behavior of textiles in the short-wave infrared (SWIR) band (1 – 2 microns) in order to identify/design potential diagnostic tools that allow the remote detection of human presence in a scene. Analyzing the spectral response of fabrics in the SWIR band has gained significant interest in the remote sensing community since it provides a potential path to discriminate camouflaged clothing from backgrounds that appear similar to the object of interest in the visible band. Existing research, originating primarily from the textiles community, has thoroughly documented the behavior of clothing fabrics in the visible band. Other …

Collaborative Research: The Effect Of Iron-Complexing Ligands On Iron Availability To Phytoplankton In Hnlc Waters Of The Subarctic Pacific Ocean, Mark L. Wells, Mary Jane Perry, Charles Trick

University of Maine Office of Research Administration: Grant Reports

Scientists from the University of Maine and San Francisco State University propose to do deck-board incubation experiments in high nutrient, low chlorophyll (HNLC) waters of the eastern (Ocean Station PAPA) and the western (Ocean Station KNOT) Subarctic Pacific Ocean to determine how Fe supply affects phytoplankton species composition. Specifically, this team of scientists plans to address the following specific objectives: (1) assess how the relative availability of Fe bound to weaker and stronger classes of ligands differs among different phytoplankton groups (cyanobacteria, diatoms, dinoflagellates, prymnesiophytes) and how these differences influence the evolution of the phytoplankton community after Fe enrichment in …

Infrared Spectroscopy In Combination With Advanced Statistical Methods For Distinguishing Viral Infected Biological Cells, Tian Tang

Mathematics Theses

Fourier Transform Infrared (FTIR) microscopy is a sensitive method for detecting difference in the morphology of biological cells. In this study FTIR spectra were obtained for uninfected cells, and cells infected with two different viruses. The spectra obtained are difficult to discriminate visually. Here we apply advanced statistical methods to the analysis of the spectra, to test if such spectra are useful for diagnosing viral infections in cells. Logistic Regression (LR) and Partial Least Squares Regression (PLSR) were used to build models which allow us to diagnose if spectral differences are related to infection state of the cells. A three-fold, …

Regressing Scalar Outcomes On Image Predictors Via Functional Principal Component Regression, Philip T. Reiss

Philip T. Reiss

No abstract provided.

Networking, William Osei-Poku

William Osei-Poku

No abstract provided.

Cariporide Prodrugs: Targeting Brain Cancer Cells Through Sodium-Proton Exchange Inhibition, Jacob Vervynckt, Johnathan Brantley, Jessica Moore, Mark Graves Ii, William Harley, Fredric A. Gorin, Hasan Palandoken

Chemistry and Biochemistry

More than 200,000 people in the United States are diagnosed with a primary or metastatic brain tumor annually. The life expectancy for these individuals is approximately 9-12 months from the time of diagnosis. This poor prognosis is due to the ineffectiveness of existing therapies (i.e., chemotherapy and radiotherapy) against brain cancer, where the primary problem is the inability to differentiate cancer cells from healthy brain cells.

Relative to healthy brain tissue, the heightened metabolism of cancer cells increases their reliance on the ion transport proteins NHE (sodium-proton exchanger) and NCX (sodium-calcium exchanger). Inhibition of these proteins disrupts the intricate pH …

Alkoxyamine Polymers: Versatile Materials For Surface Ligation Applications, Lindsey Hines, Jessica Moore, David Dahl, Belinda Lady, Johnathan Brantley, Hasan Palandoken

Chemistry and Biochemistry

Immobilization of biomolecules (i.e., proteins, carbohydrates), on polymeric surfaces has been an area of intense research. The resultant bioconjugates often display increased stability, bioavailability and activity. Our research program seeks to explore the utility of the alkoxyamine (RONH2) functional group in new materials as versatile ligating sites for the immobilization of various compounds.

The ease with which alkoxyamines (RONH2) condense with aldehydes or ketones has prompted their widespread use in labelling liposome, bacterial and mammalian cell surfaces as well as chemoselectively ligating small molecule ‘recognition elements' onto polyfunctional substrates. These condensation reactions proceed in aqueous media to afford the robust …

Synthesis And First X-Ray Structures Of Cobalt(Ii) And Cobalt(Iii) Complexes Bearing 2,4-Dioxo-Alkanoic Acid Dialkylamide Ligands, Brian Pagenkopf, Jian Wang, Nicholas A. Morra, Hongda Zhao, Vincent Lynch, Robert Mcdonald, John F. Reichwein

Chemistry Publications

The aerobic oxidation of 5-hydroxy pentenes to trans-tetrahydrofurans (THFs), the Mukaiyama oxidation, has in recent years emerged as a powerful tool in synthetic chemistry. In this report we describe the first crystal structures of 2,4-dioxo-alkanoic acid dialkylamide complexes for both Co(II) and Co(III) salts. The Co(II) structures show an unprecedented arrangement of atoms, with a central Co(II)(H₂O)₆ flanked by two Co(II) atoms each coordinated with three anionic chelating ligands. The dimeric Co(III) structures show two anionic chelating ligands and bridging hydroxyl groups.

An Optimal Principle In Fluid-Structure Interaction, Bong Jae Chung, Ashuwin Vaidya

Department of Applied Mathematics and Statistics Faculty Scholarship and Creative Works

We study the steady terminal orientation of a fore-aft symmetric body as it settles in a viscous fluid. An optimal principle for the settling behavior is discussed based upon entropy production in the system, both in the Stokes limit and the case of near equilibrium states when inertial effects emerge. We show that in the Stokes limit, the entropy production in the system is zero allowing any possible terminal orientation while in the presence of inertia, the particle assumes a horizontal position which coincides with the state of maximum entropy production. Our results are seen to agree well with experimental …

Relaxations In Ba2bisbo6 Double Complex Perovskite Ceramics, Manoel Carvalho Castro Jr., Carlos William De Araujo Paschoal, Frank C. Snyder, Michael W. Lufaso

Chemistry Faculty Research and Scholarship

The electric properties of the complex double perovskite Ba2BiSbO6 have been investigated using impedance spectroscopy in the frequency range from 1 Hz up to 1 MHz and in the temperature range from room temperature up to 560 K. There are two contributions to the electrical properties due to the grain and grain boundary. The oxygen vacancies play an important role in the conductivity and strongly increase the dielectric constant at high temperatures. The analysis of the frequency dependence of the conductivity clearly shows the structural phase transition of this compound near 515 K.

Air Compression As A Mechanism For The Underdamped Slug Test Response In Fractured Glacier Ice, Toby W. Meierbachtol, Joel T. Harper, Neil F. Humphrey, Jeremy Shaha, John H. Bradford

CGISS Publications and Presentations

Artificial perturbations of borehole water levels, known as slug tests, are a useful means of characterizing the glacier hydrologic system. Slug tests were performed on Bench Glacier, Alaska, in 21 boreholes over three field seasons during the transition from a winter to a summer drainage mode. Fifty-four slug tests were conducted, with water level monitoring in up to five boreholes adjacent to the slugged borehole. Seven of the slug tests were performed in conjunction with dye dispersion tests to identify water pathways within the slugged borehole following perturbation. Nearly 60% of monitored adjacent boreholes showed a hydraulic connection to the …

Josephson Physics Mediated By The Mott Insulating Phase, Smitha Vishveshwara, Courtney Lannert

Physics: Faculty Publications

We investigate the static and dynamic properties of bosonic lattice systems in which condensed and Mott insulating phases coexist due to the presence of a spatially varying potential. We formulate a description of these inhomogeneous systems and calculate the bulk energy at and near equilibrium. We derive the explicit form of the Josephson coupling between disjoint superfluid regions separated by Mott insulating regions. We obtain detailed estimates for the case of alternating superfluid and Mott insulating spherical shells in a radially symmetric parabolically confined cold atom system.

Air Compression As A Mechanism For The Underdamped Slug Test Response In Fractured Glacier Ice, Toby W. Meierbachtol, Joel T. Harper, Neil Humphrey, Jeremy Shaha, John Bradford

Geosciences Faculty Publications

Artificial perturbations of borehole water levels, known as slug tests, are a useful means of characterizing the glacier hydrologic system. Slug tests were performed on Bench Glacier, Alaska, in 21 boreholes over three field seasons during the transition from a winter to a summer drainage mode. Fifty-four slug tests were conducted, with water level monitoring in up to five boreholes adjacent to the slugged borehole. Seven of the slug tests were performed in conjunction with dye dispersion tests to identify water pathways within the slugged borehole following perturbation. Nearly 60% of monitored adjacent boreholes showed a hydraulic connection to the …

Fisheries Occasional Publication No.72 - Western Rock Lobster Ecological Effects Of Fishing Research Plan., Rhys Brown

Fisheries occasional publications

The commercial West Coast Rock Lobster Fishery (WCRLF) targets the western rock lobster (WRL), Panulirus cygnus, averaging approximately 10,000 tonnes of lobsters each year. Currently approximately 450 to 500 boats operate in the Fishery in waters ranging from 5 m to 200 m depth adjacent to the Western Australian coast and stretching from Cape Leeuwin in the south to Shark Bay in the north. The Fishery is managed by the Department of Fisheries (DoF) in Western Australia, using an input control system designed to constrain exploitation/fishing effort and deliver sustainable catches. The annual value of the catch is estimated at …

Modeling Natural Resources Scarcity And Proverty Effects On Fertility In Honduras, Nepal, And Tanzania, Ayoub Shaban Ayoub

UNLV Theses, Dissertations, Professional Papers, and Capstones

This dissertation examines whether the vicious circle theory applies in three developing countries characterized by high population growth. According to the vicious circle theory, natural resource scarcity coupled with poverty leads to population growth via positive effects on fertility particularly in rural areas of developing countries. Population growth then leads to a further increase in natural resource scarcity, creating a "feedback loop." This is the first study to use micro-level data to test and control for endogeneity using a two-stage Probit model (IVPROBIT). The existing literature has largely failed to address endogeneity in the relationship between natural resource scarcity and …