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2011

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Articles 211 - 240 of 10326

Full-Text Articles in Physical Sciences and Mathematics

Quality Selection For Dynamic Adaptive Streaming Over Http With Scalable Video Coding, Travis L. Andelin Dec 2011

Quality Selection For Dynamic Adaptive Streaming Over Http With Scalable Video Coding, Travis L. Andelin

Theses and Dissertations

Video streaming on the Internet is increasingly using Dynamic Adaptive Streaming over HTTP (DASH), in which the video is converted into various quality levels and divided into two-second segments. A client can then adjust its video quality over time by choosing to download the appropriate quality level for a given segment using standard HTTP. Scalable Video Coding (SVC) is a promising enhancement to the DASH protocol. With SVC, segments are divided into subset bitstream blocks. At playback, blocks received for a given segment are combined to additively increase the current quality. Unlike traditional DASH, which downloads segments serially, this encoding …

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Quantification Of Glacier Melt Volume In The Indus River Watershed, Maria Nicole Asay Dec 2011

Quantification Of Glacier Melt Volume In The Indus River Watershed, Maria Nicole Asay

Theses and Dissertations

Quantifying the contribution of glaciers to water resources is particularly important in locations where glaciers may provide a large percentage of total river discharge. In some remote locations, direct field measurements of melt rates are difficult to acquire, so alternate approaches are needed. Positive degree-day modeling (PDD) of glacier melt is a valuable tool to making first order approximations of the volume of melt coming from glaciers. In this study, a PDD-melt model is applied to glaciers in the Indus River watershed located in Afghanistan, China, India, and Pakistan. Here, millions of people rely on the water from the Indus …

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The Gravitational-Wave Memory From Eccentric Binaries, Marc Favata Dec 2011

The Gravitational-Wave Memory From Eccentric Binaries, Marc Favata

Department of Physics and Astronomy Faculty Scholarship and Creative Works

The nonlinear gravitational-wave memory causes a time-varying but nonoscillatory correction to the gravitational-wave polarizations. It arises from gravitational-waves that are sourced by gravitational-waves. Previous considerations of the nonlinear memory effect have focused on quasicircular binaries. Here I consider the nonlinear memory from Newtonian orbits with arbitrary eccentricity. Expressions for the waveform polarizations and spin-weighted spherical-harmonic modes are derived for elliptic, hyperbolic, parabolic, and radial orbits. In the hyperbolic, parabolic, and radial cases the nonlinear memory provides a 2.5 post-Newtonian (PN) correction to the leading-order waveforms. This is in contrast to the elliptical and quasicircular cases, where the nonlinear memory corrects …

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2011 Fall Engr333 Student Seminar Presentation, 2011 Fall Engr333 Dec 2011

2011 Fall Engr333 Student Seminar Presentation, 2011 Fall Engr333

ENGR 333

File for student presentation, given by students in the Fall 2010 class of ENGR333.

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Do You Believe The Climate Is Changing? Answers From New Survey Research, Lawrence C. Hamilton Dec 2011

Do You Believe The Climate Is Changing? Answers From New Survey Research, Lawrence C. Hamilton

Carsey School of Public Policy

This brief explores how political views influence Americans’ understanding and perception of science. The research is based on a national version of the Community and Environment in Rural America survey called NCERA, and on New Hampshire’s statewide Granite State Poll. Author Lawrence Hamilton reports that most people on both surveys feel that they understand either a great deal or a moderate amount about global warming or climate change. However, deep partisan divisions affect both personal beliefs about climate change and perceptions of agreement among scientists. Democrats are much more likely to state they believe that climate change is happening, caused …

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New Frontiers In Ocean Exploration: The 2011 E/V Nautilus Field Season, K. Bell, R. Ballard, D. Coleman, C. Roman, M. Brennan, T. Turanli, M. Duman, S. Carey, P. Nomikou, M. Marani, M. Rosi, J. Austin, M. Canals, J. Karson, L. Mayer, Y. Makovsky Dec 2011

New Frontiers In Ocean Exploration: The 2011 E/V Nautilus Field Season, K. Bell, R. Ballard, D. Coleman, C. Roman, M. Brennan, T. Turanli, M. Duman, S. Carey, P. Nomikou, M. Marani, M. Rosi, J. Austin, M. Canals, J. Karson, L. Mayer, Y. Makovsky

Christopher N. Roman

In the summer of 2011, the Exploration Vessel NAUTILUS is undertaking a four-month expedition to the Black, Aegean and Mediterranean Seas, and North Atlantic Ocean. The primary goal of the NAUTILUS is to create a focus of international leadership for the development and integration of leading-edge technologies, educational programs, field operations, and public outreach programs for ocean exploration, in partnership with NOAA, National Geographic Society, Office of Naval Research, and other sponsors. To do so, the program uses a complement of deep submergence vehicle systems and “telepresence” technologies to engage scientists, educators and the public, both at sea and ashore, …

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Acrb Trimer Stability And Efflux Activity, Insight From Mutagenesis Studies, Linliang Yu, Wei Lu, Yinan Wei Dec 2011

Acrb Trimer Stability And Efflux Activity, Insight From Mutagenesis Studies, Linliang Yu, Wei Lu, Yinan Wei

Chemistry Faculty Publications

The multidrug transporter AcrB in Escherichia coli exists and functions as a homo-trimer. The assembly process of obligate membrane protein oligomers, including AcrB, remains poorly understood. In a previous study, we have shown that individual AcrB subunit is capable of folding independently, suggesting that trimerization of AcrB follows a three-stage pathway in which monomers first fold, and then assemble. Here we destabilized the AcrB trimer through mutating a single Pro (P223) in the protruding loop of AcrB, which drastically reduced the protein activity. We replaced P223 separately with five residues, including Ala, Val, Tyr, Asn, and Gly, and found that …

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Mixed Discriminants, Eduardo Cattani, Maria Angelica Cueto, Alicia Dickenstein, Sandra Di Rocco, Bernd Strumfels Dec 2011

Mixed Discriminants, Eduardo Cattani, Maria Angelica Cueto, Alicia Dickenstein, Sandra Di Rocco, Bernd Strumfels

Eduardo Cattani

No abstract provided.

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Partial Connectivity In Wireless Sensor Networks, Robert Andre Murphy Dec 2011

Partial Connectivity In Wireless Sensor Networks, Robert Andre Murphy

Dissertations

Given a bounded region of the 2-dimensional plane, a discrete set of nodes is distributed throughout according to a Poisson point process. Given some fixed, finite, real number, two nodes are said to connect and form an edge if their mutual distance is less than this number. Let G be the graph of all such edges over the set of generated nodes and let C be any set of mutually connected nodes. It is shown that there is a critical mutual distance such that at least half of all generated nodes are mutually connected to form a connected cluster. Now, …

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Analyzing Ecohydrology Of Subirrigated Meadow, Dry Valley And Upland Dune Ecosystems Using Remote Sensing And In-Situ Estimations In The Semiarid Sand Hills Region Of Nebraska, Usa, Nathan C. Healey Dec 2011

Analyzing Ecohydrology Of Subirrigated Meadow, Dry Valley And Upland Dune Ecosystems Using Remote Sensing And In-Situ Estimations In The Semiarid Sand Hills Region Of Nebraska, Usa, Nathan C. Healey

School of Natural Resources: Dissertations, Theses, and Student Research

Nebraska’s dependence upon the High Plains (Ogallala) Aquifer for agricultural production is vital to the state’s economy, ecology and hydrology. The Sand Hills region (58,000 km2) of Nebraska is a unique system of lakes, (~5%) wetlands, (~10%) subirrigated meadows, (~20%) dry valleys and (~65%) upland sand dune ecosystems. Understanding how each of these land cover types reacts to climate conditions of different water limitations is vital to regional water resource management. This research explores the ecohydrological behavior of different land cover types at the Gudmundsen Sand Hills Research Laboratory (GSRL) near Whitman, Nebraska in the heart of the …

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Remote Analysis Of Grain Size Characteristic In Submarine Pyroclastic Deposits From Kolumbo Volcano, Greece, Clara Smart, D. P. Whitesell, Christopher N. Roman, Steven Carey Dec 2011

Remote Analysis Of Grain Size Characteristic In Submarine Pyroclastic Deposits From Kolumbo Volcano, Greece, Clara Smart, D. P. Whitesell, Christopher N. Roman, Steven Carey

Graduate School of Oceanography Faculty Publications

Grain size characteristics of pyroclastic deposits provide valuable information about source eruption energetics and depositional processes. Maximum size and sorting are often used to discriminate between fallout and sediment gravity flow processes during explosive eruptions. In the submarine environment the collection of such data in thick pyroclastic sequences is extremely challenging and potentially time consuming. A method has been developed to extract grain size information from stereo images collected by a remotely operated vehicle (ROV). In the summer of 2010 the ROV Hercules collected a suite of stereo images from a thick pumice sequence in the caldera walls of Kolumbo …

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Statistical Inferences For The Youden Index, Haochuan Zhou Dec 2011

Statistical Inferences For The Youden Index, Haochuan Zhou

Mathematics Dissertations

In diagnostic test studies, one crucial task is to evaluate the diagnostic accuracy of a test. Currently, most studies focus on the Receiver Operating Characteristics Curve and the Area Under the Curve. On the other hand, the Youden index, widely applied in practice, is another comprehensive measurement for the performance of a diagnostic test. For a continuous-scale test classifying diseased and non-diseased groups, finding the Youden index of the test is equivalent to maximize the sum of sensitivity and specificity for all the possible values of the cut-point. This dissertation concentrates on statistical inferences for the Youden index. First, an …

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Detection Of Diffuse Sea Floor Venting Using Structured Light Imaging, Gabrielle Inglis, Clara Smart, Christopher Roman, Steven Carey Dec 2011

Detection Of Diffuse Sea Floor Venting Using Structured Light Imaging, Gabrielle Inglis, Clara Smart, Christopher Roman, Steven Carey

Graduate School of Oceanography Faculty Publications

Efficiently identifying and localizing diffuse sea floor venting at hydrothermal and cold seep sites is often difficult. Actively venting fluids are usually identified by a temperature induced optical shimmering seen during direct visual inspections or in video data collected by vehicles working close to the sea floor. Relying on such direct methods complicates establishing spatial relations between areas within a survey covering a broad area. Our recent work with a structured light laser system has shown that venting can also be detected in the image data in an automated fashion. A structured light laser system consists of a camera and …

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Nanozeolites Doped Photopolymer Layers With Reduced Shrinkage, Mohesh Moothanchery, Izabela Naydenova, Svetlana Mintova, Vincent Toal Dec 2011

Nanozeolites Doped Photopolymer Layers With Reduced Shrinkage, Mohesh Moothanchery, Izabela Naydenova, Svetlana Mintova, Vincent Toal

Articles

An acrylamide based photopolymer doped with pure silica MFI-type zeolite (silicalite-1) nanoparticles has been characterized for holographic recording purposes. The concentrations of the silicalite-1 nanoparticles in the photopolymer layers were 1, 2.5, 5 and 7.5 wt.%. The inclusion of silicalite-1 nanoparticle in the photopolymer has resulted in an increase of the diffraction efficiency by up to 40%, and decrease of the shrinkage from 1.32% to 0.57%. The best results were obtained in layers doped with 5 wt.% silicalite-1 nanoparticles.

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The Laboca Survey Of The Extended Chandra Deep Field-South: Clustering Of Submillimetre Galaxies, Ryan C. Hickox, J. L. Wardlow, Ian Smail, A. D. Myers Dec 2011

The Laboca Survey Of The Extended Chandra Deep Field-South: Clustering Of Submillimetre Galaxies, Ryan C. Hickox, J. L. Wardlow, Ian Smail, A. D. Myers

Dartmouth Scholarship

We present a measurement of the spatial clustering of submillimetre galaxies (SMGs) at z = 1–3. Using data from the 870 μm LABOCA submillimetre survey of the Extended Chandra Deep Field South, we employ a novel technique to measure the cross-correlation between SMGs and galaxies, accounting for the full probability distributions for photometric redshifts of the galaxies. From the observed projected two-point cross-correlation function we derive the linear bias and characteristic dark matter halo masses for the SMGs. We detect clustering in the cross-correlation between SMGs and galaxies at the > 4σ level. Accounting for the clustering of galaxies from their …

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Dynamic Appointment Scheduling In Healthcare, Mckay N. Heasley Dec 2011

Dynamic Appointment Scheduling In Healthcare, Mckay N. Heasley

Theses and Dissertations

In recent years, healthcare management has become fertile ground for the scheduling theory community. In addition to an extensive academic literature on this subject, there has also been a proliferation of healthcare scheduling software companies in the marketplace. Typical scheduling systems use rule-based analytics that give schedulers advisory information from programmable heuristics such as the Bailey-Welch rule cite{B,BW}, which recommends overbooking early in the day to fill-in potential no-shows later on. We propose a dynamic programming problem formulation to the scheduling problem that maximizes revenue. We formulate the problem and discuss the effectiveness of 3 different algorithms that solve the …

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Investigating The Impact Of Restricted Irrigation Practices On Soil Moisture Variability And Distribution In A Dry Farmed Vineyard Site, Boise, Idaho, J. Duffin, David Wilkins, J. Guenther Dec 2011

Investigating The Impact Of Restricted Irrigation Practices On Soil Moisture Variability And Distribution In A Dry Farmed Vineyard Site, Boise, Idaho, J. Duffin, David Wilkins, J. Guenther

David E. Wilkins

Changing climate in semiarid regions may result in increased water stresses for agricultural production as timing and form of precipitation may result in diminished surface water for irrigation. To prepare for these changing conditions, studies are being conducted on the possibility of dry farmed agriculture as an alternative to irrigated production. This study specifically investigates the ability to grow productive wine grapes with limited or zero irrigation in the Boise Front Foothills, West Foothills TIC Vineyard, located in a climate zone receiving less than 300 mm of annual precipitation. Traditional vineyard performance factors such as planting densities, soil type, rootstock, …

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Sophomore Field Experiences As An Introduction To The Nature Of Geosciences: Data Collection And Analysis Using Dendrochronology, David Wilkins, M. Kunkel Dec 2011

Sophomore Field Experiences As An Introduction To The Nature Of Geosciences: Data Collection And Analysis Using Dendrochronology, David Wilkins, M. Kunkel

David E. Wilkins

Opportunities for field experiences are often presented as a primary reason that undergraduate students gravitate towards geosciences as a major field of study. What those students may not understand is that, for professional geoscientists, field experiences go beyond the freshman-level field trip, and students may overlook the processes of observation, data collection and analysis that are inherent to the science. The Department of Geosciences at Boise State has developed a set of sophomore field experience courses designed to "set the hook" into new majors and prepare them for field experiences in upper division coursework. These sophomore courses have been shown …

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High Resolution Sea Floor Bathymetry Using High Frequency Multibeam Sonar And Structured Light Laser Imaging, C. Roman, G. Inglis, C. Smart, I. Vaughn, S. Carey Dec 2011

High Resolution Sea Floor Bathymetry Using High Frequency Multibeam Sonar And Structured Light Laser Imaging, C. Roman, G. Inglis, C. Smart, I. Vaughn, S. Carey

Christopher N. Roman

Detailed bathymetric maps of the sea floor with centimeter level resolution can be produced by underwater vehicles using multibeam sonars and structured light laser imaging. Over spatial scales up to tens of thousands of square meters it is possible to produce maps gridded to sub centimeter levels. This level of accuracy demands detailed treatments of the sensor relative data, the vehicle navigation data and the vehicle to sensor position and rotational offsets. The presented results will show comparisons between these two sensor modalities. Data have a been collected during recent field programs to the Kolumbo volcanic crater and the Southern …

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Remote Analysis Of Grain Size Characteristic In Submarine Pyroclastic Deposits From Kolumbo Volcano, Greece, C. Smart, D. P. Whitesell, C. Roman, S. Carey Dec 2011

Remote Analysis Of Grain Size Characteristic In Submarine Pyroclastic Deposits From Kolumbo Volcano, Greece, C. Smart, D. P. Whitesell, C. Roman, S. Carey

Christopher N. Roman

Grain size characteristics of pyroclastic deposits provide valuable information about source eruption energetics and depositional processes. Maximum size and sorting are often used to discriminate between fallout and sediment gravity flow processes during explosive eruptions. In the submarine environment the collection of such data in thick pyroclastic sequences is extremely challenging and potentially time consuming. A method has been developed to extract grain size information from stereo images collected by a remotely operated vehicle (ROV). In the summer of 2010 the ROV Hercules collected a suite of stereo images from a thick pumice sequence in the caldera walls of Kolumbo …

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Detection Of Diffuse Sea Floor Venting Using Structured Light Imaging, G. Inglis, C. Smart, C. Roman, S. Carey Dec 2011

Detection Of Diffuse Sea Floor Venting Using Structured Light Imaging, G. Inglis, C. Smart, C. Roman, S. Carey

Christopher N. Roman

Efficiently identifying and localizing diffuse sea floor venting at hydrothermal and cold seep sites is often difficult. Actively venting fluids are usually identified by a temperature induced optical shimmering seen during direct visual inspections or in video data collected by vehicles working close to the sea floor. Relying on such direct methods complicates establishing spatial relations between areas within a survey covering a broad area. Our recent work with a structured light laser system has shown that venting can also be detected in the image data in an automated fashion. A structured light laser system consists of a camera and …

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Global Effects Of Climate Change On Wildfire: Causal Relationships Of Fire, The Natural Environment And Human Activities, Lindon N. Pronto Dec 2011

Global Effects Of Climate Change On Wildfire: Causal Relationships Of Fire, The Natural Environment And Human Activities, Lindon N. Pronto

Lindon N Pronto

Climate change and human activity is significantly impacting the frequency and severity of wildfires across the globe. Although climate change and human population are the overarching factors affecting wildfires in the current dialogue, the issues are more complex and often not fully understood. These issues range from global temperature increases and severe drought cycles to the relatively new phenomenon of the wildland urban interface (WUI). This is the area where structures are integrated with or immediately surrounded by areas of moderate to high fire risk and are directly linked to fuel types and topographic features. Because climate change is such …

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User Choice Between Traditional And Computerized Methods: An Activity Perspective, Jun Sun Dec 2011

User Choice Between Traditional And Computerized Methods: An Activity Perspective, Jun Sun

Information Systems Faculty Publications and Presentations

Numerous computerized methods emerge to replace traditional methods in people’s personal, work and social lives, but many are hesitant to make the transition. This study examines the factors that influence human choice between different methods. According to Activity Theory, traditional and computerized methods are both tools that a person uses for a certain task. The situated experiences with various methods shape people’s attitude toward using them later in terms of tool readiness. The understanding leads to hypothesized relationships between user-, method- and task-specific factors and the dependent variable. The results from an empirical study support that method experiences have strong …

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The Design And Evolution Of Zipcode, Anthony Skjellum, Steven G. Smith, Nathan E. Doss, Alvin Leung Dec 2011

The Design And Evolution Of Zipcode, Anthony Skjellum, Steven G. Smith, Nathan E. Doss, Alvin Leung

Steven D. Smith

Zipcode is a message-passing and process-management system that was designed for multicomputers and homogeneous networks of computers in order to support libraries and large-scale multicomputer software. The system has evolved significantly over the last five years, based on our experiences and identified needs. Features of Zipcode that were originally unique to it, were its simultaneous support of static process groups, communication contexts, and virtual topologies, forming the "mailer" data structure. Point-to-point and collective operations reference the underlying group, and use contexts to avoid mixing up messages. Recently, we have added "gather-send" and "receive-scatter" semantics, based on persistent Zipcode "invoices," both …

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Inferring Phytoplankton Carbon And Eco-Physiological Rates From Diel Cycles Of Spectral Particulate Beam-Attenuation Coefficient, G. Dall'olmo, E. Boss, M. J. Behrenfeld, T. K. Westberry, C. Courties, L. Prieur, M. Pujo-Pay, N. Hardman-Mountford, T. Moutin Dec 2011

Inferring Phytoplankton Carbon And Eco-Physiological Rates From Diel Cycles Of Spectral Particulate Beam-Attenuation Coefficient, G. Dall'olmo, E. Boss, M. J. Behrenfeld, T. K. Westberry, C. Courties, L. Prieur, M. Pujo-Pay, N. Hardman-Mountford, T. Moutin

Marine Sciences Faculty Scholarship

The diurnal fluctuations in solar irradiance impose a fundamental frequency on ocean biogeochemistry. Observations of the ocean carbon cycle at these frequencies are rare, but could be considerably expanded by measuring and interpreting the inherent optical properties. A method is presented to analyze diel cycles in particulate beam-attenuation coefficient (cp) measured at multiple wavelengths. The method is based on fitting observations with a size-structured population model coupled to an optical model to infer the particle size distribution and physiologically relevant parameters of the cells responsible for the measured diel cycle in cp. Results show that the information related to size …

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A Search For The Transit Of Hd 168443b: Improved Orbital Parameters And Photometry, Genady Pilyavsky, Suvrath Mahadevan, Stephen R. Kane, Andrew W. Howard, David R. Ciardi, Chris De Pree, Diana Dragomir, Debra A. Fischer, Gregory W. Henry, Eric L. N. Jensen, Gregory Laughlin Dec 2011

A Search For The Transit Of Hd 168443b: Improved Orbital Parameters And Photometry, Genady Pilyavsky, Suvrath Mahadevan, Stephen R. Kane, Andrew W. Howard, David R. Ciardi, Chris De Pree, Diana Dragomir, Debra A. Fischer, Gregory W. Henry, Eric L. N. Jensen, Gregory Laughlin

Information Systems and Engineering Management Research Publications

The discovery of transiting planets around bright stars holds the potential to greatly enhance our understanding of planetary atmospheres. In this work we present the search for transits of HD 168443b, a massive planet orbiting the bright star HD 168443 (V = 6.92) with a period of 58.11 days. The high eccentricity of the planetary orbit (e = 0.53) significantly enhances the a priori transit probability beyond that expected for a circular orbit, making HD 168443 a candidate for our ongoing Transit Ephemeris Refinement and Monitoring Survey. Using additional radial velocities from Keck High Resolution Echelle Spectrometer, we refined the …

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Global Change, Global Trade, And The Next Wave Of Plant Invasions, Bethany A. Bradley, Dana M. Blumenthal, Regan Early, Edwin D. Grosholz, Joshua J. Lawler, Luke P. Miller, Cascade J.B. Sorte, Carla M. D'Antonio, Jeffrey M. Diez, Jeffrey S. Dukes, Ines Ibanez, Julian D. Olden Dec 2011

Global Change, Global Trade, And The Next Wave Of Plant Invasions, Bethany A. Bradley, Dana M. Blumenthal, Regan Early, Edwin D. Grosholz, Joshua J. Lawler, Luke P. Miller, Cascade J.B. Sorte, Carla M. D'Antonio, Jeffrey M. Diez, Jeffrey S. Dukes, Ines Ibanez, Julian D. Olden

Faculty Publications, Biological Sciences

Many non-native plants in the US have become problematic invaders of native and managed ecosystems, but a new generation of invasive species may be at our doorstep. Here, we review trends in the horticultural trade and invasion patterns of previously introduced species and show that novel species introductions from emerging horticultural trade partners are likely to rapidly increase invasion risk. At the same time, climate change and water restrictions are increasing demand for new types of species adapted to warm and dry environments. This confluence of forces could expose the US to a range of new invasive species, including many …

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Designed Synthesis Of Halogenated Borazine-Linked Polymers And Their Applications In Gas Storage And Separation, Thomas Reich Dec 2011

Designed Synthesis Of Halogenated Borazine-Linked Polymers And Their Applications In Gas Storage And Separation, Thomas Reich

Theses and Dissertations

The synthesis of highly porous organic polymers with predefined porosity has attracted considerable attention due to their potential in a wide range of applications. Of particular interest in porous organic polymers is their potential use in automotive applications as well as separation processes whereby advancements could result in a reduction in carbon dioxide emissions and the production of natural gas in a more economically friendly manner. Along these pursuits, seven borazine-linked polymers (BLPs) have been synthesized through the introduction of p-phenylenediamine, 1,3,5-tris-(4-aminophenyl)benzene, benzidine, or tetra-(4-aminophenyl)methane with boron tribromide or boron trichloride followed by the thermolysis reaction of the resulting in …

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A Study Of Correlations Between The Definition And Application Of The Gene Ontology, Yuji Mo Dec 2011

A Study Of Correlations Between The Definition And Application Of The Gene Ontology, Yuji Mo

Department of Computer Electronics and Engineering: Dissertations, Theses, and Student Research

When using the Gene Ontology (GO), nucleotide and amino acid sequences are annotated by terms in a structured and controlled vocabulary organized into relational graphs. The usage of the vocabulary (GO terms) in the annotation of these sequences may diverge from the relations defined in the ontology. We measure the consistency of the use of GO terms by comparing GO's defined structure to the terms' application. To do this, we first use synthetic data with different characteristics to understand how these characteristics influence the correlation values determined by various similarity measures. Using these results as a baseline, we found that …

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Development And Optimization Of Organic Based Monoliths For Use In Affinity Chromatography, Erika L. Pfaunmiller Dec 2011

Development And Optimization Of Organic Based Monoliths For Use In Affinity Chromatography, Erika L. Pfaunmiller

Department of Chemistry: Dissertations, Theses, and Student Research

Affinity chromatography is an important and useful tool for studying biological interactions, such as the binding of an antibody with an antigen. Monolithic supports offer many advantages over traditional packed bed supports in affinity chromatography, including their ease of preparation, low back pressures and good mass transfer properties. Monoliths can be broken down into two basic categories: organic (polymer) and inorganic (silica) monoliths. There are many varieties of polymer based monoliths; however, a large focus has been on co-polymers of glycidyl methacrylate (a functional monomer) and ethylene dimethacrylate (a cross-linking agent). The solvents of choice for making this type of …

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