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2013

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Articles 11071 - 11100 of 11462

Full-Text Articles in Physical Sciences and Mathematics

A Novel Dynamic Bandwidth Selection Method For Thinning Noisy Point Clouds, Mehmet Öztürk, Zeynep Hasirci Jan 2013

A Novel Dynamic Bandwidth Selection Method For Thinning Noisy Point Clouds, Mehmet Öztürk, Zeynep Hasirci

Turkish Journal of Electrical Engineering and Computer Sciences

In this paper, we propose a dynamic bandwidth selection method for thinning noisy point clouds into curves. Due to the nonhomogeneous distribution of noise or varying curvature of the data, the thinning procedure requires a dynamically adjusted bandwidth along the curve. On the other hand, the selected local region must be sorted along a suitable direction vector for local curve fitting purposes. The contribution of this paper to the field is 2-folded: first, a normalized eigenvalue analysis-based method is used to determine the best local bandwidth. The second task is getting a good regression line of the local region for …


Stopping Spam With Sending Session Verification, Ahmet Baran Jan 2013

Stopping Spam With Sending Session Verification, Ahmet Baran

Turkish Journal of Electrical Engineering and Computer Sciences

Spam has become one of the most significant problems for Internet communication and users today. The traditional filtering methods and signature-based spam blocking systems that have come into prominence recently fall short, as statistics demonstrate that spam further mounts up day after day. In this study, a new method is recommended to block spam mails. In this recommended method, a mail sending session is verified during mail envelope communication by adding small attachments to the simple mail transfer protocol, so spam mails can be blocked before leaving the sender domain or relay machine. Additionally, hijacked user accounts are able to …


Optimal Placement And Sizing Of Distributed Generations In Distribution Systems For Minimizing Losses And Thd_V Using Evolutionary Programming, Aida Fazliana Abdul Kadir, Azah Mohamed, Hussain Shareef, Mohd Zamri Che Wanik Jan 2013

Optimal Placement And Sizing Of Distributed Generations In Distribution Systems For Minimizing Losses And Thd_V Using Evolutionary Programming, Aida Fazliana Abdul Kadir, Azah Mohamed, Hussain Shareef, Mohd Zamri Che Wanik

Turkish Journal of Electrical Engineering and Computer Sciences

Growing concerns over environmental impacts, improvement of the overall network conditions, and rebate programs offered by governments have led to an increase in the number of distributed generation (DG) units in commercial and domestic electric power production. However, a large number of DG units in a distribution system may sometimes contribute to high levels of harmonic distortion, even though the emission levels of the individual DG units comply with the harmonic standards. It is known that the nonoptimal size and nonoptimal placement of DG units may lead to high power losses, bad voltage profiles, and harmonic propagations. Therefore, this paper …


Ssr Mitigation With Sssc Thanks To Fuzzy Control, Seyed Mohammad Hassan Hosseini, Hadi Samadzadeh, Javad Olamaei, Murtaza Farsadi Jan 2013

Ssr Mitigation With Sssc Thanks To Fuzzy Control, Seyed Mohammad Hassan Hosseini, Hadi Samadzadeh, Javad Olamaei, Murtaza Farsadi

Turkish Journal of Electrical Engineering and Computer Sciences

This paper deals with the capability of a static synchronous series compensator (SSSC) to attenuate the subsynchronous resonance (SSR). Two well-known controllers are designed, namely a conventional damping controller (CDC) and fuzzy logic damping controller (FLDC). These 2 damping controllers are added to a main control loop of a SSSC operating as a SSR damping controller. It should be noted that, to optimize the parameters of the CDC, a versatile optimization technique is implemented, namely particle swarm optimization (PSO). A comprehensive comparison between the 2 control methods is carried out for different operational conditions. To observe the superior performance of …


Hybrid Spr Algorithm To Select Predictive Genes For Effectual Cancer Classification, Aruna Sundaram, Nandakishore Lellapalli Venkata, Rajagopalan Sarukai Parthasarathy Jan 2013

Hybrid Spr Algorithm To Select Predictive Genes For Effectual Cancer Classification, Aruna Sundaram, Nandakishore Lellapalli Venkata, Rajagopalan Sarukai Parthasarathy

Turkish Journal of Electrical Engineering and Computer Sciences

Designing an automated system for classifying DNA microarray data is an extremely challenging problem because of its high dimension and low amount of sample data. In this paper, a hybrid statistical pattern recognition algorithm is proposed to reduce the dimensionality and select the predictive genes for the classification of cancer. Colon cancer gene expression profiles having 62 samples of 2000 genes were used for the experiment. A gene subset of 6 highly informative genes was selected by the algorithm, which provided a classification accuracy of 93.5%.


A Video-Based Eye Pupil Detection System For Diagnosing Bipolar Disorder, Gökay Akinci, Edi̇z Polat, Orhan Murat Koçak Jan 2013

A Video-Based Eye Pupil Detection System For Diagnosing Bipolar Disorder, Gökay Akinci, Edi̇z Polat, Orhan Murat Koçak

Turkish Journal of Electrical Engineering and Computer Sciences

Eye pupil detection systems have become increasingly popular in image processing and computer vision applications in medical systems. In this study, a video-based eye pupil detection system is developed for diagnosing bipolar disorder. Bipolar disorder is a condition in which people experience changes in cognitive processes and abilities, including reduced attentional and executive capabilities and impaired memory. In order to detect these abnormal behaviors, a number of neuropsychological tests are also designed to measure attentional and executive abilities. The system acquires the position and radius information of eye pupils in video sequences using an active contour snake model with an …


Flow Velocity Measurement And Analysis Based On Froth Image Sift Features And Kalman Filter For Froth Flotation, Jinping Liu, Weihua Gui, Zhaohui Tang Jan 2013

Flow Velocity Measurement And Analysis Based On Froth Image Sift Features And Kalman Filter For Froth Flotation, Jinping Liu, Weihua Gui, Zhaohui Tang

Turkish Journal of Electrical Engineering and Computer Sciences

The flow velocity of flotation froth involves important information about the concentrate grade and the mineral recovery. It is significant to maintain the flow velocity of the froth at proper levels to achieve a good production performance in the machine vision-based process monitoring and control. However, the accurate velocity field measurement for the heavily deformed and seriously fragile froth bubbles is still a great challenge. Scale-invariant feature transform (SIFT) feature-based image matching provides an effective registration method for deformed objects, but most of the processing time would be wasted on the feature extraction and matching in irrelevant regions of the …


Automated Parameter Tuning Framework For Heterogeneous And Large Instances: Case Study In Quadratic Assignment Problem, Linda Lindawati, Zhi Yuan, Hoong Chuin Lau, Feida Zhu Jan 2013

Automated Parameter Tuning Framework For Heterogeneous And Large Instances: Case Study In Quadratic Assignment Problem, Linda Lindawati, Zhi Yuan, Hoong Chuin Lau, Feida Zhu

Research Collection School Of Computing and Information Systems

This paper is concerned with automated tuning of parameters of algorithms to handle heterogeneous and large instances. We propose an automated parameter tuning framework with the capability to provide instance-specific parameter configurations. We report preliminary results on the Quadratic Assignment Problem (QAP) and show that our framework provides a significant improvement on solutions qualities with much smaller tuning computational time.


The Pricing Model Of Cloud Computing Services, Jianhui Huang, Dan Ma Jan 2013

The Pricing Model Of Cloud Computing Services, Jianhui Huang, Dan Ma

Research Collection School Of Computing and Information Systems

Cloud computing service providers offer computing resource as a utility and software as a service over network. Many believe that Cloud computing is making an industry-wise paradigm shift for IT use. Besides its technique issues, the business feature of Cloud computing attracts our interests. Specifically the practice of Amazon EC2 introduces an interesting pricing scheme. Amazon provides users with virtual computing instances as a combination of interruptible service (i.e., spot instance) and uninterruptible service (i.e., on-demand and reserved instance). Spot instance is charged at a per use price which is dynamically changing over time; users of spot instance face the …


Accountable Trapdoor Sanitizable Signatures, Junzuo Lai, Xuhua Ding, Yongdong Wu Jan 2013

Accountable Trapdoor Sanitizable Signatures, Junzuo Lai, Xuhua Ding, Yongdong Wu

Research Collection School Of Computing and Information Systems

Sanitizable signature (SS) allows a signer to partly delegate signing rights to a predetermined party, called sanitizer, who can later modify certain designated parts of a message originally signed by the signer and generate a new signature on the sanitized message without interacting with the signer. One of the important security requirements of sanitizable signatures is accountability, which allows the signer to prove, in case of dispute, to a third party that a message was modified by the sanitizer. Trapdoor sanitizable signature (TSS) enables a signer of a message to delegate the power of sanitization to any parties at anytime …


Verifiable And Private Top-K Monitoring, Xuhua Ding, Hwee Hwa Pang Jan 2013

Verifiable And Private Top-K Monitoring, Xuhua Ding, Hwee Hwa Pang

Research Collection School Of Computing and Information Systems

In a data streaming model, records or documents are pushed from a data owner, via untrusted third-party servers, to a large number of users with matching interests. The match in interest is calculated from the correlation between each pair of document and user query. For scalability and availability reasons, this calculation is delegated to the servers, which gives rise to the need to protect the privacy of the documents and user queries. In addition, the users need to guard against the eventuality of a server distorting the correlation score of the documents to manipulate which documents are highlighted to certain …


Engagingness And Responsiveness Behavior Models On The Enron Email Network And Its Application To Email Reply Order Prediction, Byung-Won On, Ee Peng Lim, Jing Jiang, Loo Nin Teow Jan 2013

Engagingness And Responsiveness Behavior Models On The Enron Email Network And Its Application To Email Reply Order Prediction, Byung-Won On, Ee Peng Lim, Jing Jiang, Loo Nin Teow

Research Collection School Of Computing and Information Systems

In email networks, user behaviors affect the way emails are sent and replied. While knowing these user behaviors can help to create more intelligent email services, there has not been much research into mining these behaviors. In this paper, we investigate user engagingness and responsiveness as two interaction behaviors that give us useful insights into how users email one another. Engaging users are those who can effectively solicit responses from other users. Responsive users are those who are willing to respond to other users. By modeling such behaviors, we are able to mine them and to identify engaging or responsive …


Valuation Of Participation In Social Gaming, Kwansoo Kim, Byungjoon Yoo, Robert J. Kauffman Jan 2013

Valuation Of Participation In Social Gaming, Kwansoo Kim, Byungjoon Yoo, Robert J. Kauffman

Research Collection School Of Computing and Information Systems

This study examines the value of the time that a user spends to participate in a social game. We focus on how a massive multiplayer online role-playing game (MMORPG) vendor can establish prices to encourage participation and retain its players. We estimate value through an application of the hedonic pricing model and analyze a data set for an MMORPG in Korea. The results permit us to estimate the value of game-playing time in monetary terms. Based on our empirical results, we propose an economic model and conduct numerical simulation to show how a game vendor can apply differential pricing in …


Firm Strategy And The Internet In U.S. Commercial Banking, K. H. Goh, Robert J. Kauffman Jan 2013

Firm Strategy And The Internet In U.S. Commercial Banking, K. H. Goh, Robert J. Kauffman

Research Collection School Of Computing and Information Systems

As information technology (IT) becomes more accessible, sustaining any competitive advantage from it becomes challenging. This has caused some critics to dismiss IT as a less valuable resource. We argue that, in addition to being able to generate strategic advantage, IT should also be viewed as a strategic necessity that prevents competitive disadvantage in rapidly changing business environments. We test a set of hypotheses on strategic advantage and strategic necessity in the context of Internet banking investments among the entire population of the United States Federal Deposit Insurance Corporation (FDIC) banks from 2003 to 2005. We seek to understand whether …


Cqarank: Jointly Model Topics And Expertise In Community Question Answering, Liu Yang, Minghui Qiu, Swapna Gottopati, Feida Zhu, Jing Jiang, Huiping Sun, Zhong Chen Jan 2013

Cqarank: Jointly Model Topics And Expertise In Community Question Answering, Liu Yang, Minghui Qiu, Swapna Gottopati, Feida Zhu, Jing Jiang, Huiping Sun, Zhong Chen

Research Collection School Of Computing and Information Systems

Community Question Answering (CQA) websites, where people share expertise on open platforms, have become large repositories of valuable knowledge. To bring the best value out of these knowledge repositories, it is critically important for CQA services to know how to find the right experts, retrieve archived similar questions and recommend best answers to new questions. To tackle this cluster of closely related problems in a principled approach, we proposed Topic Expertise Model (TEM), a novel probabilistic generative model with GMM hybrid, to jointly model topics and expertise by integrating textual content model and link structure analysis. Based on TEM results, …


Warcreate And Wail: Warc, Wayback, And Heritrix Made Easy, Mat Kelly, Michael L. Nelson, Michele C. Weigle Jan 2013

Warcreate And Wail: Warc, Wayback, And Heritrix Made Easy, Mat Kelly, Michael L. Nelson, Michele C. Weigle

Computer Science Faculty Publications

[First slide]

The Problem

Institutional Tools, Personal Archivists

  • ON YOUR MACHINE

-Complex to Operate

-Require Infrastructure

  • DELEGATED TO INSTITUTIONS

-$$$

-Lose original perspective

  • Locale content tailoring (DC vs. San Francisco)
  • Observation Medium (PC web browser vs. Crawler)


Bacterial Colonization And Extinction On Marine Aggregates: Stochastic Model Of Species Presence And Abundance, Andrew M. Kramer, M. Maille Lyons, Fred C. Dobbs, John M. Drake Jan 2013

Bacterial Colonization And Extinction On Marine Aggregates: Stochastic Model Of Species Presence And Abundance, Andrew M. Kramer, M. Maille Lyons, Fred C. Dobbs, John M. Drake

OES Faculty Publications

Organic aggregates provide a favorable habitat for aquatic microbes, are efficiently filtered by shellfish, and may play a major role in the dynamics of aquatic pathogens. Quantifying this role requires understanding how pathogen abundance in the water and aggregate size interact to determine the presence and abundance of pathogen cells on individual aggregates. We build upon current understanding of the dynamics of bacteria and bacterial grazers on aggregates to develop a model for the dynamics of a bacterial pathogen species. The model accounts for the importance of stochasticity and the balance between colonization and extinction. Simulation results suggest that while …


Intercalibraton In Chemical Oceanography-- Getting The Right Number, Gregory A. Cutter Jan 2013

Intercalibraton In Chemical Oceanography-- Getting The Right Number, Gregory A. Cutter

OES Faculty Publications

Intercalibration has a strict metrological definition, but in brief, it's an open sharing of methods and results between laboratories to achieve the most accurate data with the fewest random and systematic errors. In the field of chemical oceanography where concentrations of many constituents can be in the nano- to picomolar range, the salt water matrix can be difficult to analyze, and knowing the exact concentrations, or even chemical forms, of biologically required elements is essential, intercalibration is a very relevant and needed tool. Implementing it is not simple because errors can occur at any step in the process of taking …


Using Ammonium Pore Water Profiles To Assess Stoichiometry Of Deep Remineralization Processes In Methanogenic Continental Margin Sediments, David J. Burdige, Tomoko Komada Jan 2013

Using Ammonium Pore Water Profiles To Assess Stoichiometry Of Deep Remineralization Processes In Methanogenic Continental Margin Sediments, David J. Burdige, Tomoko Komada

OES Faculty Publications

In many continental margin Sediments, a deep reaction zone exists which is separated from remineralization processes near the sediment surface. Here, methane diffuses upward to a depth where it is oxidized by downwardly diffusing sulfate. However, the methane sources that drive this anaerobic oxidation of methane (AOM) in the sulfate-methane transition zone (SMT) may vary among sites. In particular, these sources can be thought of as either (i) "internal" sources from in situ methanogenesis (regardless of where it occurs in the sediment column) that are ultimately coupled to organic matter deposition and burial, or (ii) "external" sources such as hydrocarbon …


Surface Production Fuels Deep Heterotrophic Respiration In Northern Peatlands, J. Elizabeth Corbett, David J. Burdige, Malak M. Tfaily, Angela R. Dial, William T. Cooper, Paul H. Glaser, Jeffrey P. Chanton Jan 2013

Surface Production Fuels Deep Heterotrophic Respiration In Northern Peatlands, J. Elizabeth Corbett, David J. Burdige, Malak M. Tfaily, Angela R. Dial, William T. Cooper, Paul H. Glaser, Jeffrey P. Chanton

OES Faculty Publications

Multiple analyses of dissolved organic carbon (DOC) from pore waters were conducted to define the processes that govern carbon balance in peatlands: (1) source, reactivity, and transport of DOC with respect to vegetation, peat, and age of carbon substrate, (2) reactivity of DOC with respect to molecular size, and (3) lability to photoxidation of surficial DOC. We found that surface organic production fuels heterotrophic respiration at depth in advection-dominated peatlands, especially in fens. Fen DOC was Δ14Cenriched relative to the surrounding fen peat, and fen respiration products were similar to this enriched DOC indicating that DOC was the …


Development And Deployment Of A Point-Source Digital Inline Holographic Microscope For The Study Of Plankton And Particles To A Depth Of 6000 M, Alexander B. Bochdansky, Manfred H. Jericho, Gerhard J. Herndl Jan 2013

Development And Deployment Of A Point-Source Digital Inline Holographic Microscope For The Study Of Plankton And Particles To A Depth Of 6000 M, Alexander B. Bochdansky, Manfred H. Jericho, Gerhard J. Herndl

OES Faculty Publications

Bochdansky, A. B., Jericho, M. H., & Herndl, G. J. (2013). Development and deployment of a point-source digital inline holographic microscope for the study of plankton and particles to a depth of 6000 m. Limnology and Oceanography: Methods, 11, 28-40. doi: 10.4319/lom.2013.11.28


Microbially Induced Sedimentary Structures Recording An Ancient Ecosystem In The Ca. 3.48 Billion-Year-Old Dresser Formation, Pilbara, Western Australia, Nora Noffke, Daniel Christian, David Wacey, Robert M. Hazen Jan 2013

Microbially Induced Sedimentary Structures Recording An Ancient Ecosystem In The Ca. 3.48 Billion-Year-Old Dresser Formation, Pilbara, Western Australia, Nora Noffke, Daniel Christian, David Wacey, Robert M. Hazen

OES Faculty Publications

Microbially induced sedimentary structures (MISS) result from the response of microbial mats to physical sediment dynamics. MISS are cosmopolitan and found in many modern environments, including shelves, tidal flats, lagoons, riverine shores, lakes, interdune areas, and sabkhas. The structures record highly diverse communities of microbial mats and have been reported from numerous intervals in the geological record up to 3.2 billion years (Ga) old. This contribution describes a suite of MISS from some of the oldest well-preserved sedimentary rocks in the geological record, the early Archean (ca. 3.48 Ga) Dresser Formation, Western Australia. Outcrop mapping at the meter to …


Isotopic (Δ13c, Δ14c) Analysis Of Organic Acids In Marine Samples Using Wet Chemical Oxidation, Susan Q. Lang, G. L. Früh-Green, S. M. Bernasconi, L. Wacker Jan 2013

Isotopic (Δ13c, Δ14c) Analysis Of Organic Acids In Marine Samples Using Wet Chemical Oxidation, Susan Q. Lang, G. L. Früh-Green, S. M. Bernasconi, L. Wacker

Faculty Publications

We present a method for the isolation and off-line isotope analysis of formate and acetate in marine samples. Organic acids are separated by high performance liquid chromatography and collected in glass Exetainer® screw-capped vials that have been prespiked with an oxidant and flushed with helium. The vials are subsequently heated to convert the organic compounds to CO2 for radiocarbon and δ13C analysis. Small aliquots are sampled for measurement of δ13C by isotope ratio mass spectrometry, whereas the majority of the CO2 is saved for radiocarbon analysis by accelerator mass spectrometry using a gas ion …


A Technical Framework For Resource Synchronization, Martin Klein, Robert Sanderson, Herbert Van De Sompel, Simeon Warner, Bernhard Haslhofer, Carl Lagoze, Michael L. Nelson Jan 2013

A Technical Framework For Resource Synchronization, Martin Klein, Robert Sanderson, Herbert Van De Sompel, Simeon Warner, Bernhard Haslhofer, Carl Lagoze, Michael L. Nelson

Computer Science Faculty Publications

This is the second paper in D-Lib Magazine about the ResourceSync effort conducted by the National Information Standards Organization (NISO) and the Open Archives Initiative (OAI). The first part provided a perspective on the resource synchronization problem and introduced a template that organized possible components of a resource synchronization framework in a modular manner. This paper details a technical framework devised using that template.


Statistical Analysis Of Microarray Data In Sleep Deprivation, Stephanie Marie Berhorst Jan 2013

Statistical Analysis Of Microarray Data In Sleep Deprivation, Stephanie Marie Berhorst

Masters Theses

"Microarray technology is a useful tool for studying the expression levels of thousands of genes or exons within a single experiment. Data from microarray experiments present many challenges for researchers since costly resources often limit the experimenter to small sample sizes and large amounts of data are generated. The researcher must carefully consider the appropriate statistical analysis to use that aligns with the experimental design employed. In this work, statistical issues are investigated and addressed for a microarray experiment that examines how expression levels change over time as individuals are sleep deprived. Over the course of 48 hours of sleep …


Characterization Of Mass Wasting Through The Spectral Analysis Of Lidar Imagery: Owyhee River, Southeastern Oregon, Christopher Earl Markley Jan 2013

Characterization Of Mass Wasting Through The Spectral Analysis Of Lidar Imagery: Owyhee River, Southeastern Oregon, Christopher Earl Markley

All Master's Theses

Quantifying landslide character is an important aspect of understanding hillslope-channel interactions. Spectral analysis of high-resolution, LiDAR derived, DEMs was carried out following methods described by Booth et al. (2009) to determine the characteristic spectral signature inherent in different styles of landslides in the Owyhee River Canyon in southeastern Oregon. The main factor in landslide generation in this location is a lithologic contact in which a coherent basaltic caprock overlies relatively weak sediments where most of the landslide failure surfaces originated. Changes in spectral power distribution through time were quantified by comparing a sequence of adjacent rotational landslides of apparent different …


3d Seismic Data Interpretation Of Boonsville Field, Texas, Aamer Ali Alhakeem Jan 2013

3d Seismic Data Interpretation Of Boonsville Field, Texas, Aamer Ali Alhakeem

Masters Theses

"The Boonsville field is one of the largest gas fields in the US located in the Fort Worth Basin, north central Texas. The highest potential reservoirs reside in the Bend Conglomerate deposited during the Pennsylvanian. The Boonsville data set is prepared by the Bureau of Economic Geology at the University of Texas, Austin, as part of the secondary gas recovery program. The Boonsville field seismic data set covers an area of 5.5 mi². It includes 38 wells data. The Bend Conglomerate is deposited in fluvio-deltaic transaction. It is subdivided into many genetic sequences which include depositions of sandy conglomerate representing …


A Structural Analysis Of The El Kasr Structure In The Western Desert Of Egypt, Trevor Charles Ellis Jan 2013

A Structural Analysis Of The El Kasr Structure In The Western Desert Of Egypt, Trevor Charles Ellis

Masters Theses

"The El Kasr structure was studied in order to investigate the origins and evolution of the enigmatic Desert Eyes structures of the Western Desert due to its accessibility and uniqueness among the structures. The El Kasr structure, an elongate structural basin with low limb dips, is unique among the "Desert Eyes" structures in that it: 1) occurs in isolation in otherwise horizontal sedimentary rock, 2) the long dimension of the basin is oriented NNW, 3) it is closely spatially associated with the less common NNW fault zones, and 4) is composite in nature. The structure was investigated using remote sensing …


Efficient Integrity Verification Of Replicated Data In Cloud, Raghul Mukundan Jan 2013

Efficient Integrity Verification Of Replicated Data In Cloud, Raghul Mukundan

Masters Theses

"The cloud computing is an emerging model in which computing infrastructure resources are provided as a service over the Internet. Data owners can outsource their data by remotely storing them in the cloud and enjoy on-demand high quality services from a shared pool of configurable computing resources. By using these data storage services, the data owners can relieve the burden of local data storage and maintenance. However, since data owners and the cloud servers are not in the same trusted domain, the outsourced data may be at risk as the cloud server may no longer be fully trusted. Therefore, data …


Intensity-Based Skeletonization Of Cryoem Gray-Scale Images Using A True Segmentation-Free Algorithm, Kamal Al Nasr, Chunmei Liu, Mugizi Rwebangira, Legand Burge, Jing He Jan 2013

Intensity-Based Skeletonization Of Cryoem Gray-Scale Images Using A True Segmentation-Free Algorithm, Kamal Al Nasr, Chunmei Liu, Mugizi Rwebangira, Legand Burge, Jing He

Computer Science Faculty Publications

Cryo-electron microscopy is an experimental technique that is able to produce 3D gray-scale images of protein molecules. In contrast to other experimental techniques, cryo-electron microscopy is capable of visualizing large molecular complexes such as viruses and ribosomes. At medium resolution, the positions of the atoms are not visible and the process cannot proceed. The medium-resolution images produced by cryo-electron microscopy are used to derive the atomic structure of the proteins in de novo modeling. The skeletons of the 3D gray-scale images are used to interpret important information that is helpful in de novo modeling. Unfortunately, not all features of the …