Physical Sciences and Mathematics Commons^™

2014 Fall Engr333 Project Final Report, John Sherwood, Jonathan Crow, Nicolaas Ourensma, Zak Devries, Andy Frandsen, Jack Kregel, Ryan Rhodes, Connor Vandongen, Schieffer Kwong, Jee Myung Kim, Matthew Deyoung, Jeff Demaagd, Tyler Devries, Doug Faber, Garrick Hershberger, Jake Derooy, Dustin Brouwer, David Evenhouse, Patrick Anderson, Thomas Brown, Ed Smit, Joel Smith, Thane Symens, Kaitlyn Weinstein, Seth Koetje, Nick Memmelaar, Austin Juza, Matt Ramaker, Ryan Demeester, Jordan Newhof, Wes Richards, Josh Vanderbyl

ENGR 333

The net-zero homes project that this class worked on throughout the semester was designed to determine what it would take to bring a home in Grand Rapids, Michigan to the status of net-zero and whether or not it is feasible to do so. The idea behind a net-zero home is to reduce the energy usage in the home, whether it is by lifestyle changes, insulation additions, or by appliance upgrades, and then produce the remaining energy deficit from renewable sources, so that the homeowner has a net usage of zero at the end of the year. This report details the …

Dynamics Of Propagation Of Premature Impulses In Structurally Remodeled Infarcted Myocardium: A Computational Analysis, Candido Cabo

Publications and Research

Initiation of cardiac arrhythmias typically follows one or more premature impulses either occurring spontaneously or applied externally. In this study, we characterize the dynamics of propagation of single (S2) and double premature impulses (S3), and the mechanisms of block of premature impulses at structural heterogeneities caused by remodeling of gap junctional conductance (Gj) in infarcted myocardium. Using a sub-cellular computer model of infarcted tissue, we found that |INa,max|, prematurity (coupling interval with the previous impulse), and conduction velocity (CV) of premature impulses change dynamically as they propagate away from the site of initiation. There are fundamental differences between the dynamics …

A More Efficient Nonparametric Test Of Symmetry Based On Overlapping Coefficient, Hani M. Samawi, Robert L. Vogel

Biostatistics Faculty Publications

In this paper we provide a more efficient nonparametric test of symmetry based on the empirical overlap coefficient using kernel density estimation applied to an extreme order statistics, namely extreme ranked set sampling. Our simulation investigation reveals that our proposed test of symmetry is at least as powerful as currently available tests of symmetry. Intensive simulation is conducted to examine the power of the proposed test. An illustration is provided using cardiac output and body weight of neonates in a neonatal intensive care unit.

Response Of Soil Nitrification To The Veterinary Pharmaceuticals Monensin, Ivermectin And Zinc Bacitracin, Magda A. Konopka

Electronic Thesis and Dissertation Repository

Pharmaceutical residues can reach agricultural land through amendment with animal or human waste. Since 2010, a series of replicated plots received annual applications of ivermectin, monensin and zinc bacitracin, either singly or in a mixture, at 0.1 mg/kg and 10 mg/kg concentrations. I collected soil samples before and after the fourth annual application of pharmaceuticals and assayed them for functional changes and amoA gene abundance, a gene needed for ammonia oxidation. In 2013, I exposed the soils to 100 mg/kg in a laboratory experiment which resulted in acceleration of nitrification. Under 10 mg/kg treatments in the field the abundance of …

Protein-Protein Interaction Network Alignment, Yu Qian

Electronic Thesis and Dissertation Repository

Proteins are some of the building blocks of organisms. They usually perform their functions by interacting with each other and forming protein complexes. A protein -protein interaction network is a graph that consists of proteins as vertices and their interactions as edges. Protein-protein interaction network alignment is very important in identifying protein complexes and predicting protein functions. Many algorithms based on graph theory have been developed to improve the accuracy of alignment, but due to the sparsity of protein-protein interactions, the result is far from satisfactory.

We propose to improve the network alignment through adding protein interactions to existing PPI …

The Effect Of Ph And Counterion On The Size Distribution And Luminescence Lifetime Of Terbium-Doped Lanthanum Nanocrystals, Sarah Baker

Undergraduate Honors Theses

In recent years, nanoparticles have been applied to and have gained prevalence in fields such as chemistry, biology, the medical sciences, and biotechnology,and have attracted the attention of medical researchers as potential microscopic drug delivery systems in the human body. In particular, nanoparticles made with the lanthanides have shown themselves to be useful to many biological applications due to their unique luminescent properties. It is crucial to determine optimum synthetic parameters so that nanoparticles are both small enough to pass through the kidneys and also have the ability to attach different functional groups so that they may be relevant to …

Star Cluster Populations In Compact Groups Of Galaxies, Konstantin Fedotov

Electronic Thesis and Dissertation Repository

In this thesis, I have explored the star cluster populations of several compact groups of galaxies, based on observations with the Advanced Camera for Surveys and the Wide Field Camera 3 on the Hubble Space Telescope. Low velocity dispersions and high galaxy number densities, the conditions of compact groups (in particular Hickson Compact Groups), represent an environment with frequent and prolonged interactions. Such environment can trigger the formation of star cluster populations associated with specific events. The BVI study has shown that star clusters can be used as a powerful tool for studying such events triggered by mergers and …

Mapping Thunder Sources By Inverting Acoustic And Electromagnetic Observations, J. F. Anderson, J. B. Johnson, R. O. Arechiga, R. J. Thomas

Geosciences Faculty Publications and Presentations

We present a new method of locating current flow in lightning strikes by inversion of thunder recordings constrained by Lightning Mapping Array observations. First, radio frequency (RF) pulses are connected to reconstruct conductive channels created by leaders. Then, acoustic signals that would be produced by current flow through each channel are forward modeled. The recorded thunder is considered to consist of a weighted superposition of these acoustic signals. We calculate the posterior distribution of acoustic source energy for each channel with a Markov Chain Monte Carlo inversion that fits power envelopes of modeled and recorded thunder; these results show which …

A Content-Sensitive Wiki Help System, Eswara Satya Pavan Rajesh Pinapala

Master's Projects

Context-sensitive help is a software application component that enables users to open help pertaining to their state, location, or the action they are performing within the software. Context-sensitive “wiki” help, on the other hand, is help powered by a wiki system with all the features of context-sensitive help. A context-sensitive wiki help system aims to make the context-sensitive help collaborative; in addition to seeking help, users can directly contribute to the help system. I have implemented a context-sensitive wiki help system into Yioop, an open source search engine and software portal created by Dr. Chris Pollett, in order to measure …

The Nax Language: Unifying Functional Programming And Logical Reasoning In A Language Based On Mendler-Style Recursion Schemes And Term-Indexed Types, Ki Yung Ahn

Dissertations and Theses

Two major applications of lambda calculi in computer science are functional programming languages and mechanized reasoning systems (or, proof assistants). According to the Curry--Howard correspondence, it is possible, in principle, to design a unified language based on a typed lambda calculus for both logical reasoning and programming. However, the different requirements of programming languages and reasoning systems make it difficult to design such a unified language that provides both. Programming languages usually extend lambda calculi with programming-friendly features (e.g., recursive datatypes, general recursion) for supporting the flexibility to model various computations, while sacrificing logical consistency. Logical reasoning systems usually extend …

Developing Professional Skills In Stem Students: Data Information Literacy, Lisa Zilinski, Megan R. Sapp Nelson, Amy S. Van Epps

Lisa Zilinski

Undergraduate STEM students are increasingly expected to have some data use skills upon graduation, whether they pursue post-graduate education or move into industry. This project was an initial foray into the application of data information literacy competencies to training undergraduate students to identify markers of data and information quality. The data consumer training appeared within two courses to help students evaluate data objects, including databases and datasets available on the Internet. The application of the Data Credibility Checklist provides a foundation for developing data reuse competencies. Based upon the initial presentation of the content, it became obvious that students need …

Integrating Path-Dependent Functionals On Yeh-Wiener Space, Ian Pierce, David Skough

Department of Mathematics: Faculty Publications

Denote by Ca,b(Q) the generalized two-parameter Yeh-Wiener space with associated Gaussian measure. We investigate several scenarios in which integrals of functionals on this space can be reduced to integrals of related functionals over an appropriate single-parameter generalized Wiener space Cˆa,ˆb[0, T ]. This extends some interesting results of R. H. Cameron and D. A. Storvick.

Kaczmarz Iterative Projection And Nonuniform Sampling With Complexity Estimates, Tim Wallace, Ali Safak Sekmen

Computer Science Faculty Research

Kaczmarz’s alternating projection method has been widely used for solving mostly over-determined linear system of equations Ax = b in various fields of engineering, medical imaging, and computational science. Because of its simple iterative nature with light computation, this method was successfully applied in computerized tomography. Since tomography generates a matrix A with highly coherent rows, randomized Kaczmarz algorithm is expected to provide faster convergence as it picks a row for each iteration at random, based on a certain probability distribution. Since Kaczmarz’s method is a subspace projection method, the convergence rate for simple Kaczmarz algorithm was developed in …

Climate-Induced Changes In The Germination Phenology Of Boechera Stricta, Samuel Johnson

Theses and Dissertations

Climate change is having demonstrable, worldwide impacts on ecological systems in ways that have modified aspects of organism behavior. Plant phenologies have responded to warmer temperatures in a variety of ways that may have implications for long-term species survival. How germination phenology changes in response to warmer climate is a largely unexplored question yet the ability of a plant to advance or delay germination in unfavorable conditions is critical for survival. Knowing the relative success and timing of germination under different climate regimes is important in understanding whether species can keep pace with the rate of climate change via migration …

Surface Functionalization Of Inorganic Substrates With Polymeric Ligands Using Raft Polymerization, Anand Viswanath

Theses and Dissertations

This work focused on using polymers to modify the surface of various inorganic substrates, ranging from TiO2, ITO, CDSe and CdS nanostructures to micron sized silica particles. The synthesis of the polymers using the RAFT technique and the characterization of the functionalized substrates were analyzed in detail to provide insights into their use for various applications. In the first part of this work, novel phosphate based RAFT agents and phosphate containing polymers, including poly(methyl methacrylate) (PMMA), poly(glycidyl methacrylate) (PGMA) and poly(dimethyl siloxane) (PDMS) were synthesized. Alkyne functionalized PGMA was used to click to ITO surfaces in a grafting-to method, and …

Temporal Constraints On Holocene Initiation And Termination Of Mound Development At An Episodic Gas Hydrate And Cold Seep System, Woolsey Mound, Northern Gulf Of Mexico, Nathan Robinson

Theses and Dissertations

Woolsey Mound is a thermogenic gas hydrate and cold seep system in the deepwater (900m) Gulf of Mexico. A set of sub-bottom seismic profiles acquired at MC-118 Woolsey Mound provide decimeter-scale vertical resolution of the upper ~50m of the subsurface throughout the lease block. Integration of these data with radiocarbon, lithostratigraphic, and biostratigraphic data from shallow gravity cores provides the basis for detailed interpretation of the mound evolution within the last 12,000 years. Uniform sedimentation during the Last Glacial Maximum and following changes in sediment distribution over MC-118 suggests modern mound activity did not begin until at least ~12ka. Development …

X-Ray Polarimetry With X-Calibur, Qingzhen Guo

Arts & Sciences Electronic Theses and Dissertations

ABSTRACT

X-Ray Polarimetry with X-Calibur

by

Qingzhen Guo

Doctor of Philosophy in Physics, Washington University in St. Louis,

September, 2014. Professor Henric Krawczynski, Chair

X-ray polarimetry is a prime tool to investigate the unexplored compact sources and to provide crucial information that other techniques can not produce. By measuring the degree and orientation of the polarization of radiation from a cosmic source, unique inferences about the morphology and the magnetic field structure can be made.

Krawczysnki's group at Washington University is working on a uniquely sensitive scattering polarimeter, X-Calibur, to be used in the focal plane of a focusing X-ray …

Poly-3-Hexylthiophene Nanorods As A Donor For Organic Photovoltaics, Dharmesh Patel

Mahurin Honors College Capstone Experience/Thesis Projects

Poly-3-hexylthiophene functionalized silsesquioxane nanorods (P3HT-NRs) were prepared by direct hydrolysis and condensation of P3HT-silane precursor using the modified Stöber method. The silane precursor was stirred in a mixture of two solvents in the presence of a base under room temperature for three different reaction times. The size, shape, and morphology of these novel nanostructures were visualized using the transmission electron microscope (TEM) and scanning electron microscope (SEM). The composition of the P3HT-NRs was confirmed by FTIR and its silane by proton NMR. Future work will focus on evaluating photovoltaic performance of these nanorods as a donor for organic photovoltaics.

Mitigating The Effects Of Climate Change With Wind Energy And Gis, Rachael Isphording, Richard Snow, Mary Snow

Publications

The climate is changing, and humans are heavily exacerbating these changes. As the effects of climate change are being felt across the planet, scientists and policy makers are uniting to increase mitigation efforts and are researching renewable, clean energy sources to reduce the amount of greenhouse gas emissions released into the atmosphere during energy production. Of the different renewable energy technologies, wind energy is one of the most researched and implemented. Over the past twenty years, researchers have been applying Geographic Information Systems (GIS) to their climate change studies. GIS allows the user to spatially view, manipulate, and analyze data …

A Survey Of Shark Population In Winyah Bay, Sc: A Comparison Of Data From 2002-2006 And From 2012-2014, Jessica Bruce

Honors Theses

As a result of a long-term longline study conducted by Coastal Carolina University, data on the population structure of sharks in Winyah Bay, SC have been recorded since 2002. The data are collected from late spring to fall each year. Two separate data sets, from 2002 to 2006 and from 2012 to 2014, were analyzed for catch per unit effort (CPUE), catch composition, sex ratios, and average precaudallengths (PCL) for males and females. The average CPUE for the 2002-2006 data set was 2.68 with a standard deviation of 0.73 while the average for the most recent data set was 3.20 …

Neutral Density Behavior From 45-90 Km Based On Rayleigh Lidar Observations Above Usu, David Barton

Physics Capstone Projects

There are over 900 nights of observations taken by the Rayleigh lidar above Utah State University from 1993 to 2004. The data have been reduced to give absolute temperatures and relative densities in the mesosphere, from 45-90 km (Herron, 2004, 2007). From the 11 years of relative density data an 11-year climatology of mesospheric densities above Logan, Utah has been created. From this climatology I have been able to normalize the 11 years of density data to the following models: the MSISe00 empirical model, the CPC (Climate Prediction Center) reanalysis model, the ERA Interim reanalysis model, and the NASA MERRA …

Polyglyoxylates: A New Class Of Triggerable Self-Immolative Polymers, Bo Fan

Electronic Thesis and Dissertation Repository

Self-immolative polymers, which degrade by an end-to-end depolymerization mechanism in response to the cleavage of a stabilizing end-cap from the polymer terminus, are of increasing interest for a wide variety of applications ranging from sensors to controlled release. However, the preparation of these materials often requires expensive, multi-step monomer syntheses and the degradation products such as quinone methides or phthalaldehydes are potentially toxic to humans and the environment. We demonstrate here that polyglyxoylates can serve as a new and versatile class of self-immolative polymers. Polymerization of the commercially available monomer ethyl glyoxylate, followed by end-capping with a 6-nitroveratryl carbonate provides …

The Impacts Of Climate Change On The World’S Economic, Political, And Demographic Structures, Dino Kanlic

Arts & Sciences Electronic Theses and Dissertations

Climate change will have negative impacts on the political, economic, and demographic structures of society. These include a rise in ethnic tensions in the Indian Sub Continent, massive immigration to Europe, regional economic collapse and political destabilization in Africa, the inundation of island nations and economic losses in the Americas among many other changes which will combine to destabilize humanity for generations. International affairs has failed to come up with a solution because global warming is a universal prevention focused problem that trades short term gains for long term losses. Global warming will be solved by the onset of grid …

Simulation Based Evaluation Of Multiscale Small Area Health Models, Purbasha Dasgupta

Theses and Dissertations

The effects of scale on the analysis of spatial data, often referred to as the modifiable areal unit problem in spatial studies, is one of the issues often encountered in small area health models. These spatial effects of scale are also seen in the areas of disease mapping where data are usually available in counts. Often there is a need to consider the different scales of aggregation that exist within count data, since inferences based on analyses can vary if we change the definition of the unit of analysis. This thesis provides a framework that describes the distribution of relative …

Modeling Mussel Mortality: Investigating The Importance Of Swash And The Potential Implications Of Changing Wave Environments, Shadow Leigh Gulledge

Theses and Dissertations

Rising sea level and increases in temperature are causing biogeographic shifts in intertidal zones and can also lead to shifts in the local vertical zonation of organisms due to changes in body temperature during aerial exposure during low tide. Swash is an important determinant of aerial body temperatures, and vulnerability of intertidal zones to changes in climate could potentially depend on how much and how often animals are cooled by waves. While wave heights (and thus swash) are generally expected to increase with climate change, anthropogenic physical structures, such as breakwaters and wave energy converters, can decrease wave height and …

Remote Sensing Satellite Image Acquisition Planning: Framework, Methods And Application, Shufan Liu

Theses and Dissertations

This dissertation explores the theories and methods of satellite remote sensing image acquisition planning within a spatial temporal context. For many time sensitive applications, such as disaster emergency response, timely acquisition of critical information is the key to intelligent and effective decision making. Remote sensing plays an important role in information collection for these time sensitive applications. Imagery collected from hundreds of remote sensing satellite sensors offer accurate, frequent and almost instantaneous data covering the Earth in a relatively short time. However, determining which satellite sensors can provide an appropriated kind of imageries during a restricted collection window for the …

Methods For Identifying Regions Of Brain Activation Using Fmri Meta-Data, Meredith A. Ray

Theses and Dissertations

Functional neuroimaging is a relatively young discipline within the neurosciences that has led to significant advances in our understanding of the human brain and progress in neuroscientific research related to public health. Accurately identifying activated regions in the brain showing a strong association with an outcome of interest is crucial in terms of disease prediction and prevention. Functional magnetic resonance imaging (fMRI) is the most widely used method for this type of study as it has the ability to measure and identify the location of changes in tissue perfusion, blood oxygenation, and blood volume. In practice, the three-dimensional brain locations …

The Geologic Implications Of The Factors That Affected Relative Sea-Level Positions In South Carolina During The Pleistocene And The Associated Preserved High-Stand Deposits, William Richardson Doar Iii

Theses and Dissertations

This work utilizes the current understanding of South Carolina geology to provide a stratigraphic review of the late-Pliocene and Pleistocene marine deposits. Almost two centuries of recorded geological study includes geomorphic and stratigraphic units that were described, proposed, revised, abandoned, and revived. Along with the history of the age assignments, changes in geological time scales, and the changes in the understanding of geological concepts, this review is necessary because two concurrent and conflicting stratigraphies exist for late-Pliocene and Pleistocene marine sediments that record multiple sea-level transgressions that were more often destructive than constructive. The result, when tested against existing geological …

Cationic Metallocene-Containing Polymers: From Synthesis To Applications, Jiuyang Zhang

Theses and Dissertations

Metallopolymers, with the combination of metals and polymeric framworks, have attracted a lot of attention during the past decades. The development of metallopolymers has been largely driven by the desire to combine the synthetic efficiency and versatility of an organic polymer framework with the unique redox, responsive and catalytic properties of inorganic metals. Among different kinds of metallopolymers, metallocene-containing polymers， have been widely utilized for applications ranging from electrochemical sensors to templates for advanced inorganic catalysts to battery materials, due to their unique physicochemical properties. In the first part of my thesis, we showed controlled/living polymerization strategies to prepare well-defined …

Toward The Combinatorial Development Of Hydrophobic-Tagged Antifolate-Directed Degradation Of Human Thymidylate Synthase, Daniel J. Menasco

Theses and Dissertations

Direct post-translational control over a protein of interest (POI) can be exploited by manipulating the cells protein quality-control systems responsible for either intracellular turnover through ubiquitination (POI half-life) or repairing and degrading misfolded proteins.1 In an effort to target and degrade a high value POI we selected the enzyme human thymidylate synthase (TS) for post-translational degradation through ligand-directed ubiquitination and hydrophobic tagging. Thymidylate synthase catalyzes the reductive methylation of 2’-deoxyuridine monophosphate (dUMP) to 2’-deoxythymidine monophosphate (dTMP). As the de novo source of dTMP the regulation of intracellular TS is strictly controlled by ubiquitinindependent proteasomal degradation mediated by an internal TS-degron …