Physical Sciences and Mathematics Commons^™

Data In Support Of Quantification Of Pyrophosphate As A Universal Approach To Determine Polymerase Activity And Assay Polymerase Inhibitors, S. Malvezzi, S. J. Sturla, Marina Tanasova

Michigan Tech Publications

Characterization of synthetic oligonucleotides and quantification of primer extension mediated by a human translesion synthesis polymerase η (Pol η) over drug-induced DNA lesions in the presence on modified nucleotide analogs is described. Extent of primer extension for each reaction was monitored by denaturing gel electrophoresis. The data was obtained to assess the performance of the fluorescence-based primer extension (PE-PiPer) assay [1] with respect to the established and conventionally used denaturing gel electrophoresis. The obtained data reflects the specific inhibition of translesion synthesis over cisplatin containing DNA with 5-OH-CTP.

Geometric Integrators With Application To Hamiltonian Systems, Hebatallah Jamil Al Sakaji

Theses

Geometric numerical integration is a relatively new area of numerical analysis. The aim is to preserve the geometric properties of the flow of a differential equation such as symplecticity or reversibility. A conventional numerical integrator approximates the flow of the continuous-time equations using only the information about the vector field, ignoring the physical laws and the properties of the original trajectory. In this way, small inaccuracies accumulated over long periods of time will significantly diminish the operational lifespan of such discrete solutions. Geometric integrators, on the other hand, are built in a way that preserve the structure of continuous dynamics, …

The Strange Evolution Of The Large Magellanic Cloud Cepheid Ogle-Lmc-Cep1812, Hilding R. Neilson, Robert G. Izzard, Nobert Langer, Richard Ignace

ETSU Faculty Works

Classical Cepheids are key probes of both stellar astrophysics and cosmology as standard candles and pulsating variable stars. It is important to understand Cepheids in unprecedented detail in preparation for upcoming Gaia, James Webb Space Telescope (JWST) and extremely-large telescope observations. Cepheid eclipsing binary stars are ideal tools for achieving this goal, however there are currently only three known systems. One of those systems, OGLE-LMC-CEP1812, raises new questions about the evolution of classical Cepheids because of an apparent age discrepancy between the Cepheid and its red giant companion. We show that the Cepheid component is actually the product of a …

Conditional Dimension In Metric Spaces: A Natural Metric-Space Counterpart Of Kolmogorov-Complexity-Based Mutual Dimension, Vladik Kreinovich, Luc Longpre, Olga Kosheleva

Departmental Technical Reports (CS)

It is known that dimension of a set in a metric space can be characterized in information-related terms -- in particular, in terms of Kolmogorov complexity of different points from this set. The notion of Kolmogorov complexity K(x) -- the shortest length of a program that generates a sequence x -- can be naturally generalized to conditionalKolmogorov complexity K(x:y) -- the shortest length of a program that generates x by using y as an input. It is therefore reasonable to use conditional Kolmogorov complexity to formulate a conditional analogue of dimension. Such a generalization has indeed been proposed, under …

Global Projections Of Intense Tropical Cyclone Activity For The Late Twenty-First Century From Dynamical Downscaling Of Cmip5/Rcp4.5 Scenarios, Thomas R. Knutson, Joseph J. Sirutis, Ming Zhao, Robert E. Tuleya, Morris Bender, Gabriel A. Vecchi, Gabriele Villarini, Daniel Chavas

CCPO Publications

Global projections of intense tropical cyclone activity are derived from the Geophysical Fluid Dynamics Laboratory (GFDL) High Resolution Atmospheric Model (HiRAM; 50-km grid) and the GFDL hurricane model using a two-stage downscaling procedure. First, tropical cyclone genesis is simulated globally using HiRAM. Each storm is then downscaled into the GFDL hurricane model, with horizontal grid spacing near the storm of 6 km, including ocean coupling (e.g., "cold wake" generation). Simulations are performed using observed sea surface temperatures (SSTs) (1980-2008) for a "control run" with 20 repeating seasonal cycles and for a late-twenty-first-century projection using an altered SST seasonal cycle obtained …

Substrate-Mediated Deactivation Of A Ru(PTBu2nBn2) Cooperative Complex, John Paul J. Bow, Paul D. Boyle, Johanna M. Blacquiere

Chemistry Publications

Ligand design for metal-ligand cooperative (MLC) catalysis is inherently more complex than that for traditional non-cooperative ligands. The basicity, sterics and structure of the acid/base group in MLC proton-transfer (PT) complexes, for instance, undoubtedly influence catalyst performance. Herein, we evaluate the highly tunable PR2NR′2 (1,5-R′-3,7-R-1,5-diaza-3,7-diphosphacyclooctane) ligand family for the first time in an organic transformation. With [Ru(Cp)(PtBu2NBn2)(MeCN)][PF6] as the catalyst, no turnover was observed in the anti-Markovnikov hydration of alkynes, a known PT MLC reaction. Treatment of the cooperative complex with phenylacetylene affords a vinylammonium product in which the pendant nitrogen atom of the PtBu2NBn2 ligand forms a Lewis acid-base …

Theoretical And Experimental Study Of (E,2e) Ionization Of The Co₂ (1ΠG) Molecule At 250 Ev, Mevlut Dogan, Zehra Nur Ozer, Murat Yavuz, Osman Alwan, Adnan Naja, Boghos B. Joulakian, Esam S M Ali, Chuangang Ning, Don H. Madison

Physics Faculty Research & Creative Works

Triple differential cross sections (TDCSs) of the electron-impact ionization of carbon dioxide are measured in the coplanar asymmetric geometry, with incident electron energy value of 250eV, and ejected electron of 37eV. We will report the experimental results in comparison with the theoretical calculations of the M3DW and TCC (type 5) calculations.

First Evidence Of Interference Effects In The Ionization Of N₂ Molecule, Zehra Nur Ozer, Hari Chaluvadi, Mevlut Dogan, James Colgan, Don H. Madison

Physics Faculty Research & Creative Works

We will present an experimental and theoretical investigation of triple differential cross sections for electron- impact ionization of nitrogen molecules at intermediate energies. A discussion of interference effects contained in the theoretical and experimental interference factors will be presented.

Hydrological Partitioning In The Critical Zone: Recent Advances And Opportunities For Developing Transferable Understanding Of Water Cycle Dynamics, Paul D. Brooks, Jon Chorover, Ying Fan, Sarah E. Godsey, Reed M. Maxwell, James P. Mcnamara, Christina Tague

Geosciences Faculty Publications and Presentations

Hydrology is an integrative discipline linking the broad array of water-related research with physical, ecological, and social sciences. The increasing breadth of hydrological research, often where subdisciplines of hydrology partner with related sciences, reflects the central importance of water to environmental science, while highlighting the fractured nature of the discipline itself. This lack of coordination among hydrologic subdisciplines has hindered the development of hydrologic theory and integrated models capable of predicting hydrologic partitioning across time and space. The recent development of the concept of the critical zone (CZ), an open system extending from the top of the canopy to the …

Umphlett Qci Sept 2015, Natalie Umphlett

High Plains Regional Climate Center: Personnel Publications

Highlights for the Basin

Temperature and Precipitation Anomalie

Streamflow

Heavy Rains Continued

Positive and Negative Impacts to Agriculture

Persistent Smoke from Wildfires

3-Month Precipitation and Temperature Outlooks

Managing Precision Dairy Farming Technologies, Barbara Alice Wadsworth, Amanda Stone, Lauren M. Mayo, Nicky Tsai, Jeffrey M. Bewley

Agriculture and Natural Resources Publications

Precision dairy farming is the use of technologies to measure physiological, behavioral, and production indicators of individual animals to improve management strategies and farm performance. These systems have the potential to detect disease and estrus and to evaluate cow comfort by monitoring activity, feeding time, lying time, mounting activity, real-time location, reticulorumen pH, rumination time, and body temperature.

The data provided by a precision dairy farming device is only valuable if it records the data properly for the right cow and is used by the producer. This factsheet will describe problems that researchers at the University of Kentucky have experienced …

Transients Of Platoons With Asymmetric And Different Laplacians, Ivo Herman, Dan Martinec, J. J. P. Veerman

Mathematics and Statistics Faculty Publications and Presentations

We consider an asymmetric control of platoons of identical vehicles with nearest-neighbor interaction. Recent results show that if the vehicle uses different asymmetries for position and velocity errors, the platoon has a short transient and low overshoots. In this paper we investigate the properties of vehicles with friction. To achieve consensus, an integral part is added to the controller, making the vehicle a third-order system. We show that the parameters can be chosen so that the platoon behaves as a wave equation with different wave velocities. Simulations suggest that our system has a better performance than other nearest-neighbor scenarios. Moreover, …

A Comparative Study Of Polyurethane Nanofibers With Different Patterns And Its Analogous Nanofibers Containing Mwcnts, Javier Macossay-Torres, Faheem A. Sheikh, Hassan Ahmad, Hern Kim, Gary L. Bowlin

Chemistry Faculty Publications and Presentations

Tissue engineering is a multidisciplinary field that has evolved in various dimensions in recent years. One of the main aspects in this field is the proper adjustment and final compatibility of implants at the target site of surgery. For this purpose, it is desired to have the materials fabricated at the nanometer scale, since these dimensions will ultimately accelerate the fixation of implants at the cellular level. In this study, electrospun polyurethane nanofibers and their analogous nanofibers containing MWCNTs are introduced for tissue engineering applications. Since MWCNTs agglomerate to form bundles, a high intensity sonication procedure was used to disperse …

Household Bush Burning Practice And Related Respiratory Symptoms In Grenada, The Caribbean, Muge Akpinar-Elci, Kareem Coomansingh, James Blando, Larissa Mark

Center for Global Health Publications

The practice of household bush burning in Grenada occurs frequently, though it is not well documented. The effects of the emissions from bush burning on respiratory health of the population have never been researched in Grenada. The goal of the study was to measure the frequency of bush burning and to investigate the relationship between bush burning practice and respiratory health in Grenada. In this cross-sectional study, a questionnaire was used to gather information from households in the parishes of St. George and St. Andrew, Grenada. In total, 225 participants were recruited and their responses on household bush burning and …

A Joint Model Of Product Properties, Aspects And Ratings For Online Reviews, Ding Ying, Jing Jiang

Research Collection School Of Computing and Information Systems

Product review mining is an important task that can benefit both businesses and consumers. Lately a number of models combining collaborative filtering and content analysis to model reviews have been proposed, among which the Hidden Factors as Topics (HFT) model is a notable one. In this work, we propose a new model on top of HFT to separate product properties and aspects. Product properties are intrinsic to certain products (e.g. types of cuisines of restaurants) whereas aspects are dimensions along which products in the same category can be compared (e.g. service quality of restaurants). Our proposed model explicitly separates the …

Candy Crushing Your Sleep, Kasthuri Jeyarajah, Meeralakshi Radhakrishnan, Steven C. H. Hoi, Archan Misra

Research Collection School Of Computing and Information Systems

Growing interest in quantified self has led to the popularity of lifelogging applications. In particular, health and wellness related applications have seen an upsurge with the advent of wearables such as the Fitbit. In this paper, we focus on the quality of sleep that directly impacts the overall wellness of individuals. In particular, in this work, we present a first of its kind study that (1) unobtrusively quantifies the quality of sleep and (2) seeks to identify attributing aspects of our daily lives such as an individual's usage of apps throughout the day and his/her physical environment that may affect …

Stafford County, Virginia Shoreline Inventory Report Methods And Guidelines, Marcia Berman, Karinna Nunez, Sharon Killeen, Tamia Rudnicky, Julie Bradshaw, Karen Duhring, David Stanhope, David Weiss, Carl Hershner

Reports

The data inventory developed for the Shoreline Inventory is based on a three tiered shoreline assessment approach. This assessment characterizes conditions that can be observed from a small boat navigating along the shoreline or by using observations made remotely at the desktop using high resolution imagery. The three tiered shoreline assessment approach divides the shorezone into three regions:

1) the immediate riparian zone, evaluated for land use; 2) the bank, evaluated for height, cover and natural protection; and 3) the shoreline, describing the presence of shoreline structures for shore protection and recreational purposes.

The 2015 Inventory for Stafford County was …

Nanoscale Alloying In Electrocatalysts, Shiyao Shan, Jinfang F. Wu, Ning Kang, Hannah Cronk, Yinguang G. Zhao, Wei Zhao, Zakiya Skeete, Joseph Pharrah, Bryan Trimm, Jin Luo, Chuan-Jian Zhong

Chemistry Faculty Scholarship

In electrochemical energy conversion and storage, existing catalysts often contain a high percentage of noble metals such as Pt and Pd. In order to develop low-cost electrocatalysts, one of the effective strategies involves alloying noble metals with other transition metals. This strategy promises not only significant reduction of noble metals but also the tunability for enhanced catalytic activity and stability in comparison with conventional catalysts. In this report, some of the recent approaches to developing alloy catalysts for electrocatalytic oxygen reduction reaction in fuel cells will be highlighted. Selected examples will be also discussed to highlight insights into the structural …

Generalized Synthesis Of Eas [E = Fe, Co, Mn, Cr] Nanostructures And Investigating Their Morphology Evolution, Prachi Desai, Nikitaa Ashokan, Manashi Nath

Chemistry Faculty Research & Creative Works

This paper illustrates a novel route for the synthesis of nanostructured transition metal arsenides including those of FeAs, CoAs, MnAs, and CrAs through a generalized protocol. The key feature of the method is the use of one-step hot-injection and the clever use of a combination of precursors which are low-melting and highly reactive such as metal carbonyls and triphenylarsine in a solventless setup. This method also facilitates the formation of one-dimensional nanostructures as we move across the periodic table from CrAs to CoAs. The chemical basis of this reaction is simple redox chemistry between the transition metals, wherein the transition …

Properties Of Catlin’S Reduced Graphs And Supereulerian Graphs, Wei-Guo Chen, Zhi-Hong Chen, Mei Lu

Scholarship and Professional Work - LAS

A graph G is called collapsible if for every even subset R ⊆ V (G), there is a spanning connected subgraph H of G such that R is the set of vertices of odd degree in H. A graph is the reduction of G if it is obtained from G by contracting all the nontrivial collapsible subgraphs. A graph is reduced if it has no nontrivial collapsible subgraphs. In this paper, we first prove a few results on the properties of reduced graphs. As an application, for 3-edge-connected graphs G of order n with d(u) + d(v) ≥ 2(n/p − …

The Ras G Domain Lacks The Intrinsic Propensity To Form Dimers, Elizaveta A. Kovrigina, Azamat R. Galiakhmetov, Evgueni Kovriguine

Chemistry Faculty Research and Publications

Ras GTPase is a molecular switch controlling a number of cellular pathways including growth, proliferation, differentiation, and apoptosis. Recent reports indicated that Ras undergoes dimerization at the membrane surface through protein-protein interactions. If firmly established this property of Ras would require profound reassessment of a large amount of published data and modification of the Ras signaling paradigm. One proposed mechanism of dimerization involves formation of salt bridges between the two GTPase domains (G domains) leading to formation of a compact dimer as observed in Ras crystal structures. In this work, we interrogated the intrinsic ability of Ras to self-associate in …

On Indistinguishability In Remote Data Integrity Checking, Xinyu Fan, Guomin Yang, Yi Mu, Yong Yu

Research Collection School Of Computing and Information Systems

With a rapid growth of data storage in the cloud, data integrity checking in a remote data storage system has become an important issue. A number of protocols, which allow remote integrity checking by a third party, have been proposed. Although those protocols are provably secure, the data privacy issues in those protocols have not been considered. We believe that these issues are equally important since the communication flows of integrity proofs from the cloud server should not reveal any useful information of the stored data. In this paper, we introduce a new definition of data privacy called ‘INDPrivacy’ by …

Cobweb: A Robust Map Update System Using Gps Trajectories, Zhangqing Shan, Hao Wu, Weiwei Sun, Baihua Zheng

Research Collection School Of Computing and Information Systems

The accuracy and completeness of a digital map plays a critical role in determining the quality of most location-based services. Unfortunately, road networks change frequently. Consequently, we study the issue of automatic map update in this paper. We propose a system called COBWEB which takes all the unmatched trajectories as input and generates the missing road segments with both the geometry properties and topology features well preserved. We conduct a comprehensive experimental study via real trajectory data generated by roughly 15,000 taxis in Singapore within a 5-month period. Compared with existing work, COBWEB demonstrates a better and more stable performance …

Tonetrack: Leveraging Frequency-Agile Radios For Time-Based Indoor Wireless, Jie Xiong, Karthikeyan Sundaresan, Kyle Jamieson

Research Collection School Of Computing and Information Systems

Indoor localization of mobile devices and tags has received much attention recently, with encouraging fine-grained localization results available with enough line-of-sight coverage and hardware infrastructure. Some of the most promising techniques analyze the time-of-arrival of incoming signals, but the limited bandwidth available to most wireless transmissions fundamentally constrains their resolution. Frequency-agile wireless networks utilize bandwidths of varying sizes and locations in a wireless band to effi- ciently share the wireless medium between users. ToneTrack is an indoor location system that achieves sub-meter accuracy with minimal hardware and antennas, by leveraging frequency-agile wireless networks to increase the effective bandwidth. Our novel …

Tagcombine: Recommending Tags To Contents In Software Information Sites, Xin Yu Wang, Xin Xia, David Lo

Research Collection School Of Computing and Information Systems

Nowadays, software engineers use a variety of online media to search and become informed of new and interesting technologies, and to learn from and help one another. We refer to these kinds of online media which help software engineers improve their performance in software development, maintenance, and test processes as software information sites. In this paper, we propose TagCombine, an automatic tag recommendation method which analyzes objects in software information sites. TagCombine has three different components: 1) multi-label ranking component which considers tag recommendation as a multi-label learning problem; 2) similarity-based ranking component which recommends tags from similar objects; 3) …

On Security Of Content-Based Video Stream Authentication, Swee Won Lo, Zhou Wei, Deng, Robert H., Xuhua Ding

Research Collection School Of Computing and Information Systems

Content-based authentication (CBA) schemes are used to authenticate multimedia streams while allowing content-preserving manipulations such as bit-rate transcoding. In this paper, we survey and classify existing transform-domain CBA schemes for videos into two categories, and point out that in contrary to CBA for images, there exists a common design flaw in these schemes. We present the principles (based on video coding concept) on how the flaw can be exploited to mount semantic-changing attacks in the transform domain that cannot be detected by existing CBA schemes. We show attack examples including content removal, modification and insertion attacks. Noting that these CBA …

Answering Why-Not Questions On Reverse Top-K Queries, Yunjun Gao, Qing Liu, Gang Chen, Baihua Zheng, Linlin Zhou

Research Collection School Of Computing and Information Systems

Why-not questions, which aim to seek clarifications on the missing tuples for query results, have recently received considerable attention from the database community. In this paper, we systematically explore why-not questions on reverse top-k queries, owing to its importance in multi-criteria decision making. Given an initial reverse top-k query and a missing/why-not weighting vector set Wm that is absent from the query result, why-not questions on reverse top-k queries explain why Wm does not appear in the query result and provide suggestions on how to refine the initial query with minimum penalty to include Wm in the refined query result. …

Evaluation And Improvement Of Procurement Process With Data Analytics, Melvin H. C. Tan, Wee Leong Lee

Research Collection School Of Computing and Information Systems

Analytics can be applied in procurement to benefit organizations beyond just prevention and detection of fraud. This study aims to demonstrate how advanced data mining techniques such as text mining and cluster analysis can be used to improve visibility of procurement patterns and provide decision-makers with insight to develop more efficient sourcing strategies, in terms of cost and effort. A case study of an organization’s effort to improve its procurement process is presented in this paper. The findings from this study suggest that opportunities exist for organizations to aggregate common goods and services among the purchases made under and across …

Information Retrieval And Spectrum Based Bug Localization: Better Together, Tien-Duy B. Le, Richard J. Oentaryo, David Lo

Research Collection School Of Computing and Information Systems

Debugging often takes much effort and resources. To help developers debug, numerous information retrieval (IR)-based and spectrum-based bug localization techniques have been proposed. IR-based techniques process textual information in bug reports, while spectrum-based techniques process program spectra (i.e., a record of which program elements are executed for each test case). Both eventually generate a ranked list of program elements that are likely to contain the bug. However, these techniques only consider one source of information, either bug reports or program spectra, which is not optimal. To deal with the limitation of existing techniques, in this work, we propose a new …

Need Accurate User Behaviour?: Pay Attention To Groups!, Kasthuri Jayarajah, Youngki Lee, Archan Misra, Rajesh Krishna Balan

Research Collection School Of Computing and Information Systems

In this paper, we show that characterizing user behaviour from location or smartphone usage traces, without accounting for the interaction of individuals in physical-world groups, can lead to erroneous results. We conducted one of the largest studies in the UbiComp domain thus far, involving indoor location traces of more than 6,000 users, collected over a 4-month period at our university campus, and further studied fine-grained App usage of a subset of 156 Android users. We apply a state-of-the-art group detection algorithm to annotate such location traces with group vs. individual context, and then show that individuals vs. groups exhibit significant …