Physical Sciences and Mathematics Commons^™

Nickel-Catalyzed Oxidative Decarboxylative (Hetero)Arylation Reactions, Aaron P. Honeycutt

Graduate Theses, Dissertations, and Problem Reports

Transition-metal-catalyzed decarboxylative coupling reactions have gained considerable attention over the past decade as an efficient route to form heterobiaryls. However, current methods for oxidative decarboxylative (hetero)arylation with unactivated C-H bonds have been limited by poor substrate scope, control of regioselectivity, and chemospecificity. This thesis describes the development of a new nickel-catalyzed oxidative decarboxylative coupling (ODC) with unactivated C-H bonds. The first chapter discusses the development of the new nickel-catalyzed ODC reaction to enable the coupling of a N,N'-bidentate directing group with a broad scope of heteroaromatic carboxylates and ortho-substituted benzoates, a scope that has not been achieved in previous …

Application Of Molecular Pathology Techniques To Understand Mechanisms Of Disease In Smallmouth Bass, Heather Leigh Walsh

Graduate Theses, Dissertations, and Problem Reports

In the Chesapeake Bay drainage, smallmouth bass Micropterus dolomieu are used as an indicator species of estrogenic contaminant exposure and have been implicated in fish kills and disease since 2005. In the Potomac River drainage, adult smallmouth bass have experienced mortality and disease and males have a high prevalence of intersex (testicular oocytes). Conversely, in the Susquehanna River drainage mortalities and disease of young-of-the-year smallmouth bass (YOY SMB) have occurred and resulted in a population shift to older and larger fish. The exact cause of these events remains unknown; however, factors such as poor water quality, contaminants, pathogens and parasites, …

Stationary Automata, Anaam Mutar Bidhan

Graduate Theses, Dissertations, and Problem Reports

In this dissertation, we investigate new automata, we call it stationary automata or ST-automata. This concept is based on the definition of TF-automaton by Wojciechowski [Woj2]. What is new in our approach is that we incorporate stationary subsets of limit ordinals of uncountable cofinality. The first objective of the thesis is to motivate the new construction of automata. This concept of ST-automata allows us to make a connection with infinite graph theory. Aharoni, Nash-Williams, and Shelah [AhNaSh] formulated a condition that is necessary and sufficient for a bipartite graph to have a matching. For a bipartite …

Syntheses Of Azepinoindole Alkaloids Cimitrypazepine, Fargesine And Hyrtioreticulins C & D, Ganesh Ghimire

Graduate Theses, Dissertations, and Problem Reports

The Watanabe-Cenini-Söderberg reductive N-heterocyclization has emerged as a powerful tool for the synthesis of a variety of functionalized indoles. Söderberg’s elaboration of this methodology has been utilized as a late-stage cyclization protocol for the synthesis of azepinoindole alkaloids, a class of natural products characterized by an azepane skeleton fused with an indole ring. Short syntheses of the naturally occurring azepino[5,4,3-cd]indole alkaloids, cimitrypazepine, fargesine, and the diastereomeric hyrtioreticulins C & D have been completed starting from commercially available tetra-substituted benzene derivatives. The key azepinoindole core in each case was assembled via an intramolecular Mizoroki-Heck reaction followed by a …

An Interspecies Investigation Of Thyroid Plasma Hormone Concentrations, Histology, And Gene Expression, Emily A. Underwood

Graduate Theses, Dissertations, and Problem Reports

A high prevalence of endocrine disrupting chemicals (EDCs) in Great Lakes Areas of Concern (AOCs) has raised concerns as to the health and fitness of fish and wildlife. It is not well understood to what extent existing contaminants, many with continuing inflows into the environment, may impact fish populations. This study provides an initial characterization of thyroid endocrine-related effects in two indigenous fish species sampled from Great Lakes AOCs. Biomonitoring was conducted on a pelagic, top predator species, smallmouth bass (Micropterus dolomieu) and benthic, omnivorous brown bullhead (Ameiurus nebulosus) at 7 sites in spring and fall …

Qualitative And Quantitative Analysis Of Carbonate Waters In The Peters Mountain Region Of Monroe County, Wv, Emily A. Bausher

Graduate Theses, Dissertations, and Problem Reports

Water in Monroe County, WV is used extensively for public and private supply and requires quantification, chemical analysis, and assessment for contamination susceptibility. Over 250 springs were previously identified in the eastern side of Monroe County on or near Peters Mountain; 14 were continuously monitored in this study. Springs were grouped based on geologic and spatial distribution: interbedded clastic-rock springs on the mountain flanks, carbonate springs in the valley, and a thermal spring associated with the St. Clair thrust fault. Clastic and carbonate springs have calcium-magnesium-bicarbonate chemistries, neutral pHs and high alkalinities; the thermal spring has calcium-magnesium-sulfate-carbonate chemistry, low pH, …

Spatial And Temporal Analysis Of Surface Water Quality In Relation To Marcellus Shale Gas Development In The Northern Panhandle Of West Virginia, Rachel Yesenchak

Graduate Theses, Dissertations, and Problem Reports

Pre-existing water chemistry data available from the West Virginia Department of Environmental Protection were used to examine temporal changes in surface water quality related to the onset of Marcellus Shale gas drilling activity in the state of West Virginia. Drilling is concentrated in the northwestern portion of the state. Watersheds were delineated for twelve discrete stream sampling locations in the Upper Ohio-Wheeling HUC-8 sub-basin, where shale gas drilling is prevalent. Kruskal-Wallis tests were deployed to compare pre- and post-drilling concentrations of conductivity, chloride, and total suspended solids for each location. Increased concentrations of these parameters are associated with surface water …

Hydrogeology And Water Management In The Arkwright Underground Coal Mine, Pittsburgh Seam, Northern West Virginia, Bryant D. Mountjoy

Graduate Theses, Dissertations, and Problem Reports

Arkwright #1 is a closed underground mine in the Pittsburgh coal seam near Morgantown, West Virginia USA. Arkwright shares perimeter boundaries/barriers with three other closed Pittsburgh seam mines (Osage #3, Jordan #93, Federal #1) and is partially overlain by flooded Sewickley seam mines, 25 m above it. This mine is significant primarily because it manages and treats water diverted from nearly 20 other closed mines over a 600 square kilometer area. This study examines water levels, pump records, and mine maps to describe the hydrogeology of Arkwright Mine. After closure in 1995, Arkwright and the adjacent northern Osage mines began …

Integrating Microscale Enzyme And Lectin Reactions Using Nanogel Assisted Capillary Electrophoresis, Srikanth Gattu

Graduate Theses, Dissertations, and Problem Reports

Protein glycosylation is one of the most prevalent post-translational modifications which plays an important role in determining the structure, stability, and function of proteins. Changes in glycosylation patterns are a hallmark of cancer and other diseases. Characterizing glycosylation is difficult because these structures vary in their linkage and monomer sequence, which gives rise to vast microheterogenity that could affect the function of the molecule. A novel method using capillary gel electrophoresis by integrating microscale enzymes and lectin reactions in the capillary was developed to verify glycan structure by analyzing monosaccharides. Capillary electrophoresis (CE) improves upon conventional methods of glycan structure …

Understanding The Novice Decision-Making Process In Forensic Footwear Examinations: Accuracy And Decision Rules, Madonna A. Nobel

Graduate Theses, Dissertations, and Problem Reports

The reproducibility of experienced-based forensic pattern interpretation is founded on the notion that domain-specific knowledge can be successfully distributed and applied among experts within a group. This assumption persists, even when the examination is complicated by variations in case circumstances, such as impression clarity and totality, as well as media, substrate, collection mechanism and enhancement. While it is further theorized that many of these factors (as well as additional confounding factors) are at play during an examination, the manner and extent to which these sources of variability affect the examination of footwear evidence remain unclear. In order to explore this …

Boundization, Closure And Convergence For The Ultra Extended Complex Banach And Hilbert Spaces With Applications, Salah Hamad

Graduate Theses, Dissertations, and Problem Reports

We study Boundization, Closure and Convergence of Complex Banach and Hilbert spaces. We augment a Banach space with elements “infinity” and turn the augmented set into a metric space by appropriate distance functions. This new metric space is called the Ultra Extended Banach Space. A new family of bijections, motivated by nonlinear projections, take an Ultra Extended Banach Space into bounded subsets of a “larger” Banach space. We compare the family of new metrics induced and show which ones are equivalent and which ones are unexpectedly not equivalent. Some applications are provided.

Algorithmic Issues In Some Disjoint Clustering Problems In Combinatorial Circuits, Zola Nailah Donovan

Graduate Theses, Dissertations, and Problem Reports

As the modern integrated circuit continues to grow in complexity, the design of very large-scale integrated (VLSI) circuits involves massive teams employing state-of-the-art computer-aided design (CAD) tools. An old, yet significant CAD problem for VLSI circuits is physical design automation. In this problem, one needs to compute the best physical layout of millions to billions of circuit components on a tiny silicon surface. The process of mapping an electronic design to a chip involves several physical design stages, one of which is clustering. Even for combinatorial circuits, there exist several models for the clustering problem. In particular, we consider the …

Multi-Telescope Radio Observations For Low Frequency Gravitational Wave Astrophysics, Megan L. Jones

Graduate Theses, Dissertations, and Problem Reports

The North American Nanohertz Observatory for Gravitational Waves (NANOGrav) has the principal goal of detecting gravitational waves (GWs) in the nanohertz part of the spectrum using pulsar timing. This thesis presents results from radio campaigns at frequencies from 322 MHz to 10 GHz aimed at both multi-messenger constraints on GW sources and improving the timing sensitivity. The primary expected source of GWs at the nanohertz frequencies to which pulsar timing is sensitive are supermassive black hole (SMBH) binaries. We investigate a purported SMBH displaced from the galactic photocenter in NGC 3115. We explore the possibilities that the source is a …

Wintering American Black Duck Ecology Of Central Appalachia, Sara E. Yannuzzi

Graduate Theses, Dissertations, and Problem Reports

The American black duck (Anas rubripes) is a species of dabbling duck found only in the northeastern part of North America, and widely hunted until its decline. Since the 1950s, the total population has decreased by 53%. Habitat degradation and decline of wintering and breeding wetlands, historic overharvest, and interactions with the mallard (A. platyrhynchos) are attributed as some of the main causes of the black duck population’s decrease. Many policies and taxa- and habitat-specific joint ventures have since been created to aid in studying and improving North American wetlands and black duck populations throughout both their breeding and wintering …

The Use Of Item Response Theory In Survey Methodology: Application In Seat Belt Data, Mark K. Ledbetter, Norou Diawara, Bryan E. Porter

Mathematics & Statistics Faculty Publications

Problem: Several approaches to analyze survey data have been proposed in the literature. One method that is not popular in survey research methodology is the use of item response theory (IRT). Since accurate methods to make prediction behaviors are based upon observed data, the design model must overcome computation challenges, but also consideration towards calibration and proficiency estimation. The IRT model deems to be offered those latter options. We review that model and apply it to an observational survey data. We then compare the findings with the more popular weighted logistic regression. Method: Apply IRT model to the observed data …

Numerical Simulation For A Rising Bubble Interacting With A Solid Wall: Impact, Bounce, And Thin Film Dynamics, Changjuan Zhang, Jie Li, Li-Shi Luo, Tiezheng Qian

Mathematics & Statistics Faculty Publications

Using an arbitrary Lagrangian-Eulerian method on an adaptive moving unstructured mesh, we carry out numerical simulations for a rising bubble interacting with a solid wall. Driven by the buoyancy force, the axisymmetric bubble rises in a viscous liquid toward a horizontal wall, with impact on and possible bounce from the wall. First, our simulation is quantitatively validated through a detailed comparison between numerical results and experimental data. We then investigate the bubble dynamics which exhibits four different behaviors depending on the competition among the inertial, viscous, gravitational, and capillary forces. A phase diagram for bubble dynamics has been produced using …

The Beauty Of Numbers In Nature: Mathematical Patterns And Principles From The Natural World [Book Review], John A. Adam

Mathematics & Statistics Faculty Publications

(First paragraph) It came as quite a shock at the time. I cannot recall exactly when it happened, but it certainly caught me by surprise. For most of my life, and certainly from elementary school (or “primary” school in the UK) through high school I had become used to seeing posters and books illustrating the “standard” map of the world: the Mercator projection. Of course, Greenwich, London, sat at longitude 0◦ (and still does!). And certainly I knew that planet Earth is spheroidal and that this flat projection distorted the shapes and areas (especially near the polar regions), but somehow …

Dimensional Analysis: Physical Insight Gained Through Algebra, John A. Adam

Mathematics & Statistics Faculty Publications

No abstract provided.

Magnetron Sputtering Of Nb3Sn For Srf Cavities, Md. N. Sayeed, H. Elsayed-Ali, G. V. Eremeev, M. J. Kelley, U. Pudasaini, C. E. Reece

Electrical & Computer Engineering Faculty Publications

Nb₃Sn is a potential candidate for surface material of SRF cavities since it can enable the cavity to operate at higher temperatures with high quality factor and at an increased accelerating gradient. Nb-Sn films were deposited using magnetron sputtering of individual Nb and Sn targets onto Nb and sapphire substrates. The as-deposited films were annealed at 1200 °C for 3 hours. The films were characterized for their structure by X-ray Diffraction (XRD), morphology by Field Emission Scanning Electron Microscopy (FESEM), and composition by Energy Dispersive X-ray Spectroscopy (EDS) and Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS). The …

Effects Of Light Reflection On Spatial Visualization Ability And Implications For Engineering Technology Students, Petros Katsioloudis, Mildred Jones

STEMPS Faculty Publications

Results from a number of studies indicate that the type of light generated by the reflection on the surface of different types of surfaces can influence the spatial visualization ability; however, research provides inconsistent results. Considering this, a quasi-experimental study was conducted to identify the existence of statistically significant effects on spatial visualization ability as measured by the Mental Cutting Test and Sectional View drawing ability due to the impacts of light reflection. In particular, the study compared three types of light reflection; mirror, specular and diffuse and whether a significant difference exists among engineering technology students. According to the …

Transient Lattice Deformations Of Crystals Studied By Means Of Ultrafast Time-Resolved X-Ray And Electron Diffraction, Runze Li, Kyle Sundqvist, Jie Chen, H. E. Elsayed-Ali, Jie Zhang, Peter M. Rentzepis

Electrical & Computer Engineering Faculty Publications

Ultrafast lattice deformation of tens to hundreds of nanometer thick metallic crystals, after femtosecond laser excitation, was measured directly using 8.04 keV subpicosecond x-ray and 59 keV femtosecond electron pulses. Coherent phonons were generated in both single crystal and polycrystalline films. Lattice compression was observed within the first few picoseconds after laser irradiation in single crystal aluminum, which was attributed to the generation of a blast force and the propagation of elastic waves. The different time scales of lattice heating for tens and hundreds nanometer thick films are clearly distinguished by electron and x-ray pulse diffraction. The electron and lattice …

Positive Definite Functions And Dual Pairs Of Locally Convex Spaces, Daniel Alpay, Saak Gabriyelyan

Mathematics, Physics, and Computer Science Faculty Articles and Research

Using pairs of locally convex topological vector spaces in duality and topologies defined by directed families of sets bounded with respect to the duality, we prove general factorization theorems and general dilation theorems for operator-valued positive definite functions.

On The Efficacy Of High-Dose Ascorbic Acid As Anticancer Treatment: A Literature Survey, Florentin Smarandache, Victor Christianto

Branch Mathematics and Statistics Faculty and Staff Publications

Vitamin C (ascorbic acid, ascorbate) has a controversial history in cancer treatment. Emerging evidence indicates that ascorbate in cancer treatment deserves re-examination. As research results concerning ascorbate pharmacokinetics and its mechanisms of action against tumor cells have been published, and as evidence from case studies has continued to mount that ascorbate therapy could be effective if the right protocols were used, interest among physicians and scientists has increased.

Rough Neutrosophic Digraphs With Application, Florentin Smarandache, Sidra Sayed, Nabeela Ishfaq, Muhammad Akram

Branch Mathematics and Statistics Faculty and Staff Publications

A rough neutrosophic set model is a hybrid model which deals with vagueness by using the lower and upper approximation spaces. In this research paper, we apply the concept of rough neutrosophic sets to graphs. We introduce rough neutrosophic digraphs and describe methods of their construction. Moreover, we present the concept of self complementary rough neutrosophic digraphs. Finally, we consider an application of rough neutrosophic digraphs in decision-making.

Mental Models And Neutrosophic Cognitive Maps (Modelos Mentales Y Mapas Cognitivos Neutrosóficos), Maykel Leyva-Vazquez, Rebeca Escobar-Jara, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this work, elements related to mental models elicitation and analysis are addressed through causal models. Issues related to the need to include indeterminacy in causal relationships through neutrophic cognitive maps are discussed. A proposal for static analysis in neutrosophic cognitive maps is presented. The following activities are included in the proposal: Calculate, measures of centrality, Classify nodes, De-neutrosification, and Ranking nodes. As future works, the incorporation of new metrics of centrality in neutrosophic cognitive maps is proposed. The inclusion of scenario analysis to the proposal is another area of future work.

Neutropsychic Personality / A Mathematical Approach To Psychology (Third Enlarged Edition), Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

Neutropsyche is the psychological theory that studies the soul or spirit using the neutrosophy and neutrosohic theories. In other words: Neutrosophic Psychological Theory. It is based on triadic neutrosophic psychological concepts of the form (A, neutA, antiA).

Neutropsychic Personality is a neutrosophic dynamic open psychological system of tendencies to feel, think, and act specific to each individual, based on

Neutrosophic Refined Memory: that restructured the division of memory into: consciousness, aconsciousness (which we introduce as a blend of consciousness and unconsciousness), and unconsciousness. Aconscious was further subdivided into preconscious, subconscious, semiconscious = semiunconscious, subunconscious, and preunconscious …

Mod Rectangular Natural Neutrosophic Numbers, Florentin Smarandache, K. Ilanthenral, W.B. Vasantha Kandasamy

Branch Mathematics and Statistics Faculty and Staff Publications

In this book authors introduce the new notion of MOD rectangular planes. The functions on them behave very differently when compared to MOD planes (square). These are different from the usual MOD planes. Algebraic structures on these MOD rectangular planes are defined and developed. However we have built only MOD interval natural neutrosophic products

Application Of Machine Learning On Fracture Interference, Dennis Wayne Chamberlain Jr.

Graduate Theses, Dissertations, and Problem Reports

A method has been developed that locates and determines well-to-well hydraulic fracture interference (frac-hit) in shale plays using hard data. This method uses Artificial Neural Networks (ANN) with designated parameters and target outputs in conjunction with graphs of gas flowrate, tubing pressure, and cumulative gas prediction. The method was created to address the significant increase in frac-hit occurrences due to the infill wells being completed in shale plays. The production data of the well is first cleaned to eliminate outliers in the initial timeframe of the well and periods of no production so that the ANN model can be accurately …

Habitat Suitability Of Restored Wetlands And An Investigation Of Sampling Bias For Freshwater Turtles In West Virginia, Alissa L. Gulette

Graduate Theses, Dissertations, and Problem Reports

Loss and drainage of wetlands in the United States has been remediated in part by wetland restoration on agricultural lands through the Agricultural Conservation Easement Program (ACEP), operated by the Natural Resources Conservation Service. Freshwater turtles are important components of wetland ecosystems, where they contribute to nutrient cycling, storage, and transfer between terrestrial and aquatic systems, and function as apex predators. In 2016 and 2017, we investigated use of wetlands restored through the ACEP program in West Virginia by two common freshwater turtle species, snapping turtles (Chelydra serpentina) and painted turtles (Chrysemys picta), and obtained comparative data from reference wetlands. …

An Analysis Of Multiple Stressors On Resident Benthic Communities In A California Agricultural Stream, Lenwood W. Hall Jr., Ronald D. Anderson, William D. Killen, Raymond W. Allen Iii

Office of the Provost (TUN) Publications and Research

This 3-year study (2015-2017) was designed to characterize benthic communities (macroinvertebrates) and physical habitat in an agriculturally dominated waterbody in the Central Coast area of California (Santa Maria River). Benthic communities as represented by various metrics that represent richness, composition, tolerance/intolerance and trophic measures were used as response variables for the various stressors described below. Concurrent water quality evaluations, physical sediment parameters (grain size and total organic carbon [TOC]), pyrethroids, bulk metals—including simultaneously extracted metals (SEM) and acid volatile sulfides (AVS) ratios—and nutrients were measured. The relationship of various benthic metrics to physical habitat metrics, pyrethroids, metals, nutrients and sediment …