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Articles 1471 - 1500 of 12585
Full-Text Articles in Physical Sciences and Mathematics
Electrospun Nanofibers: Shaping The Future Of Controlled And Responsive Drug Delivery., Michael Joshua Wildy, Ping Lu
Electrospun Nanofibers: Shaping The Future Of Controlled And Responsive Drug Delivery., Michael Joshua Wildy, Ping Lu
College of Science & Mathematics Departmental Research
Electrospun nanofibers for drug delivery systems (DDS) introduce a revolutionary means of administering pharmaceuticals, holding promise for both improved drug efficacy and reduced side effects. These biopolymer nanofiber membranes, distinguished by their high surface area-to-volume ratio, biocompatibility, and biodegradability, are ideally suited for pharmaceutical and biomedical applications. One of their standout attributes is the capability to offer the controlled release of the active pharmaceutical ingredient (API), allowing custom-tailored release profiles to address specific diseases and administration routes. Moreover, stimuli-responsive electrospun DDS can adapt to conditions at the drug target, enhancing the precision and selectivity of drug delivery. Such localized API …
A Bayesian Network-Based Methodology For Improved Bridge Load Rating And Asset Management, Jeffery Mark Roberts
A Bayesian Network-Based Methodology For Improved Bridge Load Rating And Asset Management, Jeffery Mark Roberts
Dissertations and Theses
From the day a new structure is made available for use, to the day that the structure is no longer able to fulfill an intended purpose, structural safety is a vital interest. Managing a portfolio of structures can be a difficult undertaking for an asset manager, particularly if different types of structures are being maintained. The goal is to manage assets in the most efficient manner which can be influenced by, at a minimum, safety and financial concerns.
A potential tool for an asset manager or owner is the use of Bayesian Networks (BNs). When a BN is used to …
11.6.2023, Liz Williamson
Effect Of Hf Alloying On Magnetic, Structural, And Magnetostrictive Properties In Feco Films For Magnetoelectric Heterostructure Devices, Thomas Mion, Margo Staruch, Konrad Bussmann, Goran Karapetrov, Olaf Van 'T Erve, Sara Mills, Heonjune Ryou, Ramasis Goswami, Patrick G. Callahan, David J. Rowenhorst, Syed B. Qadri, Samuel Lofland, Peter Finkel
Effect Of Hf Alloying On Magnetic, Structural, And Magnetostrictive Properties In Feco Films For Magnetoelectric Heterostructure Devices, Thomas Mion, Margo Staruch, Konrad Bussmann, Goran Karapetrov, Olaf Van 'T Erve, Sara Mills, Heonjune Ryou, Ramasis Goswami, Patrick G. Callahan, David J. Rowenhorst, Syed B. Qadri, Samuel Lofland, Peter Finkel
College of Science & Mathematics Departmental Research
Materials with high magnetoelectric coupling are attractive for use in engineered multiferroic heterostructures with applications such as ultra-low power magnetic sensors, parametric inductors, and non-volatile random-access memory devices. Iron-cobalt alloys exhibit both high magnetostriction and high saturation magnetization that are required for achieving significantly higher magnetoelectric coupling. We report on sputter-deposited (Fe0.5Co0.5)1-xHfx (x = 0 - 0.14) alloy thin films and the beneficial influence of Hafnium alloying on the magnetic and magnetostrictive properties. We found that co-sputtering Hf results in the realization of the peening mechanism that drives film stress from highly tensile to slightly compressive. Scanning electron microscopy and …
The Age Of Synthetic Realities: Challenges And Opportunities, João Phillipe Cardenuto, Jing Yang, Rafael Padilha, Renjie Wan, Daniel Moreira, Haoliang Li, Shiqi Wang, Fernanda Andaló, Sébastien Marcel, Anderson Rocha
The Age Of Synthetic Realities: Challenges And Opportunities, João Phillipe Cardenuto, Jing Yang, Rafael Padilha, Renjie Wan, Daniel Moreira, Haoliang Li, Shiqi Wang, Fernanda Andaló, Sébastien Marcel, Anderson Rocha
Computer Science: Faculty Publications and Other Works
Synthetic realities are digital creations or augmentations that are contextually generated through the use of Artificial Intelligence (AI) methods, leveraging extensive amounts of data to construct new narratives or realities, regardless of the intent to deceive. In this paper, we delve into the concept of synthetic realities and their implications for Digital Forensics and society at large within the rapidly advancing field of AI. We highlight the crucial need for the development of forensic techniques capable of identifying harmful synthetic creations and distinguishing them from reality. This is especially important in scenarios involving the creation and dissemination of fake news, …
System-Level Noise Performance Of Coherent Imaging Systems, Derek J. Burrell, Joshua H. Follansbee, Mark F. Spencer, Ronald G. Driggers
System-Level Noise Performance Of Coherent Imaging Systems, Derek J. Burrell, Joshua H. Follansbee, Mark F. Spencer, Ronald G. Driggers
Faculty Publications
We provide an in-depth analysis of noise considerations in coherent imaging, accounting for speckle and scintillation in addition to “conventional” image noise. Specifically, we formulate closed-form expressions for total effective noise in the presence of speckle only, scintillation only, and speckle combined with scintillation. We find analytically that photon shot noise is uncorrelated with both speckle and weak-to-moderate scintillation, despite their shared dependence on the mean signal. Furthermore, unmitigated speckle and scintillation noise tends to dominate coherent-imaging performance due to a squared mean-signal dependence. Strong coupling occurs between speckle and scintillation when both are present, and we characterize this behavior …
Preface: Special Issue On Nlp Approaches To Offensive Content Online, Marcos Zampieri, Isabelle Augenstein, Siddharth Krishnan, Joshua Melton, Preslav Nakov
Preface: Special Issue On Nlp Approaches To Offensive Content Online, Marcos Zampieri, Isabelle Augenstein, Siddharth Krishnan, Joshua Melton, Preslav Nakov
Natural Language Processing Faculty Publications
No abstract provided.
Re: Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Residential Metals Abatement Program (Rmap) Peoples Park Soil Remedial Action Work Plan (Dated November 2, 2023), Nikia Greene
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Dynamic Regulation Of Store-Operated Calcium Entry By Protein S-Acylation, Goutham Kodakandla
Dynamic Regulation Of Store-Operated Calcium Entry By Protein S-Acylation, Goutham Kodakandla
Theses and Dissertations
Calcium plays a pivotal role in many physiological functions in cells. Cytosolic calcium levels are finely tuned by calcium ion channels, pumps, and intracellular organelles. Store-operated calcium entry (SOCE) is when depletion of endoplasmic reticulum (ER) calcium stores activates a calcium sensor known as stromal interaction molecule 1 (STIM1). Activation of STIM1 leads to a conformational change from a compact state to an extended state. This extended state of STIM1 allows it to bind to a calcium channel in the plasma membrane (PM) known as Orai1. The binding of Orai1 and STIM1 leads to opening of Orai1 channels and calcium …
Developing 3d Printed Integrated Microfluidic Devices For Microchip Electrophoresis Separation Of Preterm Birth Biomarkers, Joule E. Esene
Developing 3d Printed Integrated Microfluidic Devices For Microchip Electrophoresis Separation Of Preterm Birth Biomarkers, Joule E. Esene
Theses and Dissertations
Preterm birth is a global health challenge and the leading cause of neonatal mortality. Each year, about 15 million babies are born preterm globally. Traditional tools that have been exploited for the detection of preterm birth biomarkers are expensive, time consuming, or lack multiplexing capabilities. The work described in this dissertation highlights techniques developed to detect preterm birth biomarkers rapidly and accurately in the effort to mitigate preterm birth risk. In this dissertation, I first demonstrated the use of stereolithography digital light processing-based 3D printing and microfluidics for the development of microfluidic devices that had microvalves for fluid control. I …
Integrating Embeddings From Multiple Protein Language Models To Improve Protein O-Glcnac Site Prediction, Suresh Pokharel, Pawel Pratyush, Hamid D. Ismail, Junfeng Ma, Dukka Kc
Integrating Embeddings From Multiple Protein Language Models To Improve Protein O-Glcnac Site Prediction, Suresh Pokharel, Pawel Pratyush, Hamid D. Ismail, Junfeng Ma, Dukka Kc
Michigan Tech Publications, Part 2
O-linked β-N-acetylglucosamine (O-GlcNAc) is a distinct monosaccharide modification of serine (S) or threonine (T) residues of nucleocytoplasmic and mitochondrial proteins. O-GlcNAc modification (i.e., O-GlcNAcylation) is involved in the regulation of diverse cellular processes, including transcription, epigenetic modifications, and cell signaling. Despite the great progress in experimentally mapping O-GlcNAc sites, there is an unmet need to develop robust prediction tools that can effectively locate the presence of O-GlcNAc sites in protein sequences of interest. In this work, we performed a comprehensive evaluation of a framework for prediction of protein O-GlcNAc sites using embeddings from pre-trained protein language models. In particular, we …
Long-Acting Cabotegravir And The Emergence Of Drug-Resistant Hiv, Katharine Gurski
Long-Acting Cabotegravir And The Emergence Of Drug-Resistant Hiv, Katharine Gurski
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Utilizing Non-Negative Least Squares For Data-Driven Discovery Of Dynamics, Tracey G. Oellerich
Utilizing Non-Negative Least Squares For Data-Driven Discovery Of Dynamics, Tracey G. Oellerich
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Effect Of Under-Reporting, Vaccine Efficiency And Social Behavior On Epidemic Progression, Samiran Ghosh, Samiran Ghosh
Effect Of Under-Reporting, Vaccine Efficiency And Social Behavior On Epidemic Progression, Samiran Ghosh, Samiran Ghosh
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Risk Management Meets Politics And The General Public: Is Risk Management Increasing Risk, Rodger Singley
Risk Management Meets Politics And The General Public: Is Risk Management Increasing Risk, Rodger Singley
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Baa-Ttling Sore Mouth In Sheep With Mathematical Modeling, David C. Elzinga, W. Christopher Strickland
Baa-Ttling Sore Mouth In Sheep With Mathematical Modeling, David C. Elzinga, W. Christopher Strickland
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Incorporating Adaptive Human Behavior Into Epidemiological Models Using Equation Learning, Austin Barton, Jordan Klein, Jonathan Greer, Kevin Flores, Patrick Haughey
Incorporating Adaptive Human Behavior Into Epidemiological Models Using Equation Learning, Austin Barton, Jordan Klein, Jonathan Greer, Kevin Flores, Patrick Haughey
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Computational Modeling Using A Novel Continuum Approach Coupled With Pathway-Informed Neural Networks To Optimize Dynein-Mediated Centrosome Positioning In Polarized Cells, Arkaprovo Ghosal, Padmanabhan Seshaiyar Dr., Adriana Dawes Dr., General Genomics Inc.
Computational Modeling Using A Novel Continuum Approach Coupled With Pathway-Informed Neural Networks To Optimize Dynein-Mediated Centrosome Positioning In Polarized Cells, Arkaprovo Ghosal, Padmanabhan Seshaiyar Dr., Adriana Dawes Dr., General Genomics Inc.
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
An Ode Model For Investigating The Sleep-Pain Relationship In Sickle Cell Disease, Quindel Jones, Angela Reynolds, Rebecca Segal, Reginald Mcgee
An Ode Model For Investigating The Sleep-Pain Relationship In Sickle Cell Disease, Quindel Jones, Angela Reynolds, Rebecca Segal, Reginald Mcgee
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Environmental, Ecological, And Epidemiological Applications: Introduction To Mathematical Modeling, Suzanne Sumner
Environmental, Ecological, And Epidemiological Applications: Introduction To Mathematical Modeling, Suzanne Sumner
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Scicomm To The Rescue, Becky Sanft, Angel Kaur, Evan Couzo, Sally Wasileski, Jessica Pisano
Scicomm To The Rescue, Becky Sanft, Angel Kaur, Evan Couzo, Sally Wasileski, Jessica Pisano
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
A Multi-Model Approach To Understanding Growth, Reproduction, And Life History Strategies In Bromeliads, Erin N. Bodine
A Multi-Model Approach To Understanding Growth, Reproduction, And Life History Strategies In Bromeliads, Erin N. Bodine
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Understanding Impact Of Educational Awareness And Vaccines As Optimal Control Mechanisms For Changing Human Behavior In Disease Epidemics, Manal Badgaish, Dr. Padmanabhan Seshaiyer
Understanding Impact Of Educational Awareness And Vaccines As Optimal Control Mechanisms For Changing Human Behavior In Disease Epidemics, Manal Badgaish, Dr. Padmanabhan Seshaiyer
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Parameter Estimation In Epidemiological And Climate Models Using Ensemble Smoothing With Multiple Data Assimilation, Emmanuel Fleurantin
Parameter Estimation In Epidemiological And Climate Models Using Ensemble Smoothing With Multiple Data Assimilation, Emmanuel Fleurantin
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
From Formulas To Futures: Mathematical Insights Into Endosomal Escape, Fnu Nisha
From Formulas To Futures: Mathematical Insights Into Endosomal Escape, Fnu Nisha
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling, Analysis, And Simulation Of High School Student Mental Health Using Compartmental Models And Physics Informed Neural Networks, Sashwat Ravishankar, Padmanabhan Seshaiyer
Modeling, Analysis, And Simulation Of High School Student Mental Health Using Compartmental Models And Physics Informed Neural Networks, Sashwat Ravishankar, Padmanabhan Seshaiyer
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Modeling-Forward Initiatives In Differential Equations, Laura Ellwein
Modeling-Forward Initiatives In Differential Equations, Laura Ellwein
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Using A Coupled Integral Projection Model To Investigate Interspecific Competition During An Invasion: An Application To Silver Carp (Hypophthalmichthys Molitrix) And Gizzard Shad (Dorosoma Cepedianum), James Peirce
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Msis-Capaldi: Modelling The Winter Tick Epizootic In Moose, Charlotte Beckford
Msis-Capaldi: Modelling The Winter Tick Epizootic In Moose, Charlotte Beckford
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.
Bayesian Adaptive Smoothing For Activation Detection In Fmri, Juan Florez
Bayesian Adaptive Smoothing For Activation Detection In Fmri, Juan Florez
Annual Symposium on Biomathematics and Ecology Education and Research
No abstract provided.