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2024

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Articles 1681 - 1710 of 8401

Full-Text Articles in Physical Sciences and Mathematics

Novel Physics In Unconventional Superconductors, Adil Amin Aug 2024

Novel Physics In Unconventional Superconductors, Adil Amin

Theses and Dissertations

In this work, we consider the interplay of different magnetic orders and superconductivity.We consider both phenomenological and microscopic models to capture these interactions. The models are built using group theoretic arguments to ensure the constraints provided by the crystal symmetry are satisfied. We first consider a phenomenological theory for two transitions in superfluid 3He which involves coupling superfluidity and spin fluctuations through an approach called spin fluctuation feedback effect. We then apply this phenomenological approach to UPt3, PrOs4Sb12 and U1−xThxBe13 to obtain a common underlying mechanism for two superconducting transitions. We then consider odd-parity multipolar antiferromagnetic order i.e. Kramers’ degenerate …


Enhancing Interactions Among Dipole Excitations Using Surface Plasmon Polaritons: Quantum Entanglement And Classical Interactions, Jay Berres Aug 2024

Enhancing Interactions Among Dipole Excitations Using Surface Plasmon Polaritons: Quantum Entanglement And Classical Interactions, Jay Berres

Theses and Dissertations

The interaction of light with matter at the nano-scale continues to be an important research area for the application of nano-optical devices in wide ranging areas such as biosensing, light harnessing, and optical communications, to name a few. An important aspect of this is the interaction among dipole excitations (which includes classical dipole emitters, and dipole approximations of atoms, molecules, and other quantum objects), mediated by the device medium where they are located. Since the dimensions of these devices, by design, are at the nano-scale, the size of the dipole-dipole interaction space is much less than the wavelength of light …


Mixdown Altitudes As A Method Of Forecasting Peak Wind Gusts Under High-Pressure Conditions, Danica Brezovar Aug 2024

Mixdown Altitudes As A Method Of Forecasting Peak Wind Gusts Under High-Pressure Conditions, Danica Brezovar

Theses and Dissertations

Wind gusts are small-scale weather phenomena characterized by sudden, brief increases in wind speed (American Meteorological Society 2023), posing significant forecasting challenges due to their small spatial and temporal scales. These gusts are typically assumed to be caused by turbulent eddies circulating fast winds aloft down to the surface. Accurate forecasting of wind gusts is crucial across various sectors, including wind energy, structural engineering, and electric power distribution, where gusts can cause substantial economic impacts. Current forecasting methods either rely on the dynamical assumption that boundary layer turbulence mixes momentum down to the surface or predominantly statistical methods that typically …


High Temperature Alteration Conditions Within Lava Tubes: An Analogue For Venus Surface Geology, Dylan Alexander Childs Aug 2024

High Temperature Alteration Conditions Within Lava Tubes: An Analogue For Venus Surface Geology, Dylan Alexander Childs

Theses and Dissertations

Scientific exploration of other planetary bodies comes with many limitations, and Venus is no exception. Average surface temperatures of ∼460°C and an atmospheric pressure of ∼96 bars has severely limited the longevity of any instruments sent to the surface of Venus. Furthermore, with an atmosphere composed of ∼96.5% CO2, there are only three wavelength windows in the near infrared region that can be used to measure the mineralogical composition of the surface. Due to these constraints, our understanding of Venus’ surface mineralogy is severely limited and to date direct measurements of its geologic composition are limited to a handful of …


A Heuristic Approach To Operations And Control Of Btm-Ders For Bill Management And Grid Services, Md Arshad Rashid Shaon Aug 2024

A Heuristic Approach To Operations And Control Of Btm-Ders For Bill Management And Grid Services, Md Arshad Rashid Shaon

UNLV Theses, Dissertations, Professional Papers, and Capstones

Behind-The-Meter (BTM) distributed energy resources (DERs) have emerged as a critical and transformative force within the energy sector. These decentralized energy assets, which include solar photovoltaic (PV) systems, battery energy storage systems (BESS), and thermostatically controlled loads (TCLs), are increasingly essential for empowering customers by granting them greater control over their energy production and consumption, thereby reducing reliance on centralized power sources. Additionally, they have the potential to play a pivotal role in enhancing grid resilience by providing grid services. This study investigates the management of customer electricity bills and grid services through the integration of various BTM-DERs, particularly solar …


Image Processing Techniques For Water Droplet Penetration Time And Contact Angle Estimation, Sai Balaji Jai Kumar Aug 2024

Image Processing Techniques For Water Droplet Penetration Time And Contact Angle Estimation, Sai Balaji Jai Kumar

UNLV Theses, Dissertations, Professional Papers, and Capstones

Water droplet behavior on soil surfaces plays a critical role in numerous environmental processes, including soil erosion, hydrological dynamics, and ecosystem health. Accurate characterization of soil water repellency, quantified by parameters such as water droplet penetration time (WDPT) and contact angles (WDCA), is essential for informed decision-making in agricultural management, forestry practices, and land-use planning. Despite the significance of these parameters, challenges exist in reliably estimating them due to the complex and dynamic nature of soil-water interactions. This thesis address challenges in estimating WDPT and WDCA, by leveraging state-of-the-art image processing techniques and machine learning algorithms. The research focuses on …


Mining Gambling Data For Modeling Gambling Behavior Patterns, Piyush Aniruddha Puranik Aug 2024

Mining Gambling Data For Modeling Gambling Behavior Patterns, Piyush Aniruddha Puranik

UNLV Theses, Dissertations, Professional Papers, and Capstones

Understanding player behavior for responsible gambling research is a difficult task due to the lack of data on players’ activities. Past studies in this area are largely limited to publicly available behavioral data or aggregated players data. Problem gambling in gamblers is typically identified only after they have already been addicted or have already been engaging in problematic gambling behavior. Furthermore, “risky” gambling behavior has historically been difficult to define due to the varying patterns of gambling activity that could potentially be attributed to it.In this dissertation we illustrate the methodology and algorithms used to engineer financial data for further …


Effects Of Climate Change On (Semi)-Arid Ecosystems In The Southwestern United States, Charlotte Van Der Nagel Aug 2024

Effects Of Climate Change On (Semi)-Arid Ecosystems In The Southwestern United States, Charlotte Van Der Nagel

UNLV Theses, Dissertations, Professional Papers, and Capstones

Climate change is considered amongst the most severe threats to terrestrial and aquatic ecosystems globally. Ecosystems in the southwestern United States have specifically been impacted by intense drought conditions since 2000. Higher temperatures combined with altered precipitation stresses many ecosystems; however, ecosystem specific responses to such stressors may vary. Here, the effects of climate change on semi-arid ecosystems are analyzed for some of the most vulnerable ecosystems in the southwestern United States: lacustrine, riparian, and dryland ecosystems.

Lakes and reservoirs in arid environments often serve as drinking water sources and recreational areas where high water quality is essential. Climate change …


Implementing General Moment Equations For Parallel Closures In Nimrod, Hankyu Lee Aug 2024

Implementing General Moment Equations For Parallel Closures In Nimrod, Hankyu Lee

All Graduate Theses and Dissertations, Fall 2023 to Present

Understanding how magnetic fields impact plasma transport is essential for improving the efficiency of thermonuclear fusion power plants. To address the transport problem, both plasma fluid equations and Maxwell’s equations must be solved. To solve these equations, it is necessary to derive closure relations that allow the system to be closed. Previous closure models are useful for describing the behavior of high-collisionality plasma but are not effective at low collisionality. To obtain closure relations valid for low collisionality, the first-order drift kinetic equation must be solved.

This study presents methods for numerically obtaining parallel closures for NIMROD code by deriving …


Enhancing Monthly Streamflow Prediction Using Meteorological Factors And Machine Learning Models In The Upper Colorado River Basin, Saichand Thota Aug 2024

Enhancing Monthly Streamflow Prediction Using Meteorological Factors And Machine Learning Models In The Upper Colorado River Basin, Saichand Thota

All Graduate Theses and Dissertations, Fall 2023 to Present

Understanding and predicting streamflow along river basins is vital for planning future developments and ensuring safety, especially with climate change challenges. Our study focused on forecasting streamflow at Lees Ferry, a key location along the Colorado River in the Upper Colorado River Basin. We employed four machine learning models - Random Forest Regression, Long short-term memory, Gated Recurrent Unit, and Seasonal Auto-Regressive Integrated Moving Average; and combined historical streamflow data with meteorological factors such as snow water equivalent, temperature, and precipitation. Our analysis spanned 30 years of data from 1991 to 2020.

Our findings revealed that the Random Forest Regression …


Advancing Telehealth Through Artificial Intelligence: Incorporating Emotional Intelligence And Addressing Cybersecurity Challenges, Mahima Rajendra Pulgaonkar Aug 2024

Advancing Telehealth Through Artificial Intelligence: Incorporating Emotional Intelligence And Addressing Cybersecurity Challenges, Mahima Rajendra Pulgaonkar

Electronic Theses, Projects, and Dissertations

This culminating experience project explores the integration of Emotional Artificial Intelligence (Emotional AI) into telehealth systems, addressing the dual challenges of enhancing patient care and mitigating cybersecurity risks. The research questions are: (Q1) How can Emotionally Intelligent AI improve telehealth systems' ability to recognize and respond to mental health symptoms? and (Q2) What are the specific cybersecurity challenges associated with AI in telehealth and how can they be mitigated? The findings for each question are: Q1: Emotionally Intelligent AI can significantly enhance telehealth by providing personalized, empathetic interactions that improve patient engagement, adherence to treatment plans, and early detection of …


Invasion Potential Of Nonnative Fishes Through A Large Western Dam Into A Prized And Vulnerable Ecosystem, Barrett T. Friesen Aug 2024

Invasion Potential Of Nonnative Fishes Through A Large Western Dam Into A Prized And Vulnerable Ecosystem, Barrett T. Friesen

All Graduate Theses and Dissertations, Fall 2023 to Present

Native river fish face threats from habitat fragmentation, water overallocation, invasive species establishment, and powerful synergies amongst these factors. In the Colorado River Basin, USA, these threats coalesce at Glen Canyon Dam (GCD), which impounds the Colorado River to create Lake Powell, a reservoir inhabited by nonnative fish species. There is widespread concern low water level in Lake Powell may allow nonnative fish to escape through the dam, adversely affecting native fish species downstream in the Grand Canyon. In this study we characterized the seasonal distribution of nonnative fishes in the vicinity of GCD and identified environmental conditions that may …


Fishing Vessel Detection In Exclusive Economic Zones From Low Earth Orbit Satellites With Power And Computational Constraints, Kyler E. Nelson Aug 2024

Fishing Vessel Detection In Exclusive Economic Zones From Low Earth Orbit Satellites With Power And Computational Constraints, Kyler E. Nelson

All Graduate Theses and Dissertations, Fall 2023 to Present

Illegal fishing activities pose a significant threat to the sustainability of marine ecosystems and the economies and societies which rely on them. Detection of fishing vessels engaging in illegal activity is difficult, as many ships engaging in such activity actively avoid detection through radio systems used for maritime traffic monitoring. Satellite imagery provides a promising means for detecting fishing vessels, though designing an effective system is difficult due to limited availability of labeled image datasets of fishing vessels. This research proposes a system to detect illegal fishing activity through the use of a low-power ship detection satellite and proposes a …


Silica Fault Mirror Development Along The Cordillera Blanca Detachment Fault, Peru, Kayla Michelle Chaudoir Aug 2024

Silica Fault Mirror Development Along The Cordillera Blanca Detachment Fault, Peru, Kayla Michelle Chaudoir

All Graduate Theses and Dissertations, Fall 2023 to Present

Earthquakes occur along planes of geologic weakness called faults. Thin, light-reflective surfaces on faults are called fault mirrors and often considered signatures of previous earthquakes along these faults. The Cordillera Blanca mountain range in the Peruvian Andes provides a natural laboratory to explore meter scale exposures of fault mirrors. Three naturally formed fault mirror samples were collected from the Cordillera Blanca detachment fault which runs along the edge of the Cordillera Blanca mountain range. Prior work on this fault reveals that it is capable of destructive earthquakes every few thousand years and is a significant earthquake hazard to the surrounding …


Metal Assisted O2-Dependent Carbon-Carbon Bond Cleavage Of Β-Diketones And Flavonols, Stephen N. Anderson Aug 2024

Metal Assisted O2-Dependent Carbon-Carbon Bond Cleavage Of Β-Diketones And Flavonols, Stephen N. Anderson

All Graduate Theses and Dissertations, Fall 2023 to Present

Almost everything we interact with on a daily basis has been synthesized by chemists ranging from plastics, food preservatives, and medications. The diversity of synthetic molecules are achieved by the formation of new bonds between existing molecules and/or through the cleaving of bonds found in a molecule. There are uncountable amount of conditions reported to facilitate chemical reactions which all depend on the nature of molecules being used and the environment it is used in.

In recent years, more attention has been paid to identify chemical reactions that can use more environmentally favorable conditions and reduce the use of limited …


Shedding Light On Past Ice-Free Intervals In Northwest Greenland: Luminescence Dating Of The Base Of The Camp Century Ice Core, Hawke Woznick Aug 2024

Shedding Light On Past Ice-Free Intervals In Northwest Greenland: Luminescence Dating Of The Base Of The Camp Century Ice Core, Hawke Woznick

All Graduate Theses and Dissertations, Fall 2023 to Present

The goal of this thesis is to provide greater resolution on the age and character of the subglacial sediment recovered from the base of the Camp Century ice core, northwestern Greenland. Geochemical analysis indicated that the upper sub-ice sediments were geochemically different and experienced greater weathering than the basal unit underlying a one-meter silty ice lens. Analysis of feldspars within the very fine sand fraction indicates they are dominated by potassium feldspar. Sediment was dated using luminescence, which provides an age for the last time sediment was exposed to light. Luminescence analysis returned ages around 420 thousand years old, which …


Advancing Thermal Property Measurements And Water Management For Controlled Environment Agriculture On Earth And Beyond, Chihiro Dixon Aug 2024

Advancing Thermal Property Measurements And Water Management For Controlled Environment Agriculture On Earth And Beyond, Chihiro Dixon

All Graduate Theses and Dissertations, Fall 2023 to Present

Space exploration stands as one of humanity's most profound endeavors, and plant growth in space is essential for sustaining astronauts during long-duration missions. However, operating plant growth systems under reduced gravity conditions presents challenges, particularly in ensuring uniform water distribution in the root zone. Non-uniform water distribution such as excess water and/or insufficient water in the root zone can significantly impact plant yield, necessitating the need to accurately estimate water status in the root zone and understand the dynamics of water flow in plant growth media under reduced gravity conditions. The objectives of this research were to enhance the accuracy …


Interactions Between Nano/Micro-Sized Particles And Microbes For Agricultural And Environmental Applications, Li-Ting Yen Aug 2024

Interactions Between Nano/Micro-Sized Particles And Microbes For Agricultural And Environmental Applications, Li-Ting Yen

All Graduate Theses and Dissertations, Fall 2023 to Present

Among the challenges posed by a growing global population, diminishing arable land and water resources affected by climate change are critical for enhancing crop yields, ensuring food security, and maintaining water quality and environmental health.

Iron (Fe), an essential micronutrient, is vital to plant growth. The partially oxidized form of vivianite, metavivianite (metaVT), is reported to be a promising alternative Fe fertilizer. Previous studies have shown the effectiveness of bulk metaVT on plants grown on calcareous soil for mitigating Fe efficiency and the extremely low solubility of bulk metaVT (Ksp=10-36) in electrolyte solutions, such as CaCl2. …


Creating A Virtual Hierarchy From A Relational Database, Yucong Mo Aug 2024

Creating A Virtual Hierarchy From A Relational Database, Yucong Mo

All Graduate Theses and Dissertations, Fall 2023 to Present

In data management and modeling, the value of the hierarchical model is that it does not require expensive JOIN operations at runtime; once the hierarchy is built, the relationships among data are embedded in the tree-like hierarchical structure, and thus querying data could be much faster than using a relational database. Today most data is stored in relational databases, but if the data were stored in hierarchies, what would these hierarchies look like? And more importantly, would this transition lead to a more efficient database? This thesis explores these questions by introducing a set of algorithms to convert a relational …


An Examination Of The Effects Of Prey Density, Mortality, Nutrients, And Foraging Tradeoffs On A System With Inducible Defenses: An Empirical And Theoretical Approach, Benjamin C. Ralston Daniel Aug 2024

An Examination Of The Effects Of Prey Density, Mortality, Nutrients, And Foraging Tradeoffs On A System With Inducible Defenses: An Empirical And Theoretical Approach, Benjamin C. Ralston Daniel

All Graduate Theses and Dissertations, Fall 2023 to Present

To grasp the functioning and stability of ecosystems, it is important to understand species interactions. With many ecosystems becoming more imperiled from urbanization and anthropogenic influences it is important to understand ways in which species can adapt to rapid changes in their environment. Phenotypic plasticity is one such tool at nature’s disposal to initiate rapid change, where species with the same genetic makeup can have different expressed traits depending on their environment. Inducible defenses are one such form of phenotypic plasticity in which prey can express different levels and forms of defense depending on the threat of predation present in …


Soil Additives And Alternative Crops For Drought Defense In The Intermountain West, Tina M. Sullivan Aug 2024

Soil Additives And Alternative Crops For Drought Defense In The Intermountain West, Tina M. Sullivan

All Graduate Theses and Dissertations, Fall 2023 to Present

The Western U.S. looks for water optimization and conservation as agriculture is the largest water diverter, and resources are pressured by urban growth, winter snowpack instability, and drought persistence. Agricultural producers have several potential options to optimize water use with different investments associated with them. Options with varying levels of risks and known management practices include alternative crops, soil wetting agents, and crop biologicals.

An alternative crop that grew incredibly fast in popularity was industrial hemp (Cannabis sativa) despite limited agronomic knowledge for best management practices. Field trials occurred (2020-2022) near Logan, UT to test a total of …


A Comprehensive And Interactive Visualization Tool To Support Equitable Adoption Of Electrified Transportation, Aashay Maheshwarkar Aug 2024

A Comprehensive And Interactive Visualization Tool To Support Equitable Adoption Of Electrified Transportation, Aashay Maheshwarkar

All Graduate Theses and Dissertations, Fall 2023 to Present

As urban areas continue to grow, the deployment of electric vehicle (EV) charging infrastructure becomes crucial for sustainable development. This study is focused on the development of a data visualization tool that integrates diverse datasets, including traffic patterns, Points of Interest (POI), pollution levels, and socioeconomic indicators, to analyze the current state and potential expansion of EV charging stations. Our visualization tool highlights the significant impact of EV infrastructure on reducing urban pollution and improving socioeconomic outcomes. Areas with a higher density of charging stations show significantly lower levels of unemployment and pollution, emphasizing the dual benefits of EV adoption. …


Using Digitized Building And Weather Records To Improve The Accuracy Of Ground To Roof Snow Load Ratio Estimations, Gideon Parry Aug 2024

Using Digitized Building And Weather Records To Improve The Accuracy Of Ground To Roof Snow Load Ratio Estimations, Gideon Parry

All Graduate Theses and Dissertations, Fall 2023 to Present

Reliability target loads refer to the amount of accumulated snow a roof needs to be able to support to ensure that the probability of collapse is sufficiently low. Since ground snow weight, or load, is much easier to measure than roof snow load, models for roof snow loads rely on ground snow load measurements along with a statistical model that estimates roof snow retention as a ratio of the measured ground snow load. This thesis focuses on improving the roof snow retention model using data from Canadian case studies that include information about building geometry and local wind speeds. This …


Hydrogen Stable Isotope Constraints On Hydration Of Colorado Plateau Lower Crust From Oligocene-Miocene Navajo Volcanic Field Xenoliths, Shelby Dianne Litton Aug 2024

Hydrogen Stable Isotope Constraints On Hydration Of Colorado Plateau Lower Crust From Oligocene-Miocene Navajo Volcanic Field Xenoliths, Shelby Dianne Litton

All Graduate Theses and Dissertations, Fall 2023 to Present

Understanding flat-slab subduction is crucial as it involves the horizontal movement of an oceanic plate beneath a continental margin over a long distance. This tectonic process is widespread yet not fully understood, particularly regarding how it influences the chemical makeup of the continental plate and recycling in the hydrosphere. By analyzing isotopes, which are variations of certain elements found in minerals and water, we can gain insights into the sources of chemicals and geological processes at play. Our study area included six locations within the Navajo volcanic field (NVF), a region in the Colorado Plateau. We analyzed 23 lower crustal …


Implementing Radformation At Personalized Radiation Oncology: Enhancing Efficiency And Precision, Devin J. Peart Aug 2024

Implementing Radformation At Personalized Radiation Oncology: Enhancing Efficiency And Precision, Devin J. Peart

UNLV Theses, Dissertations, Professional Papers, and Capstones

RadMachine is a data quality management application implemented at Personalized Radiation Oncology (PRO) to streamline quality assurance (QA) tests. It offers various functions assisting medical physicists in a radiation oncology clinic, including inputting, analyzing, managing, exporting, and monitoring QA data. Physicists create test lists following the recommendations provided by the American Association of Medical Physics (AAPM). These lists track results for units such as the Varian Edge, Varian BRAVOS, and Siemens SOMATOM go.Open Pro CT scanner. Ancillary equipment used for testing also has assigned test lists to store calibration factors and receive calibration expiration reminders. The primary goal of utilizing …


Application Of Machine Learning Algorithms In Healthcare, Dwaipayan Mukhopadhyay Aug 2024

Application Of Machine Learning Algorithms In Healthcare, Dwaipayan Mukhopadhyay

UNLV Theses, Dissertations, Professional Papers, and Capstones

Machine Learning (ML) is a subset of artificial intelligence that has made substantial strides in predicting and identifying health emergencies, disease populations, and disease state and immune response, amongst a few fields of healthcare. Here we provide a brief overview of machine learning-based approaches and learning algorithms. Second, we discuss a general procedure of ML and review some studies presented in ML application for several healthcare fields. We also briefly discuss the risks and challenges of ML application to healthcare.This dissertation also consists of four different cases in healthcare where we have applied ML techniques on real life data sets. …


Nonfactoid Question Answering As Query-Focused Summarization With Graph-Enhanced Multihop Inference, Yang Deng, Wenxuan Zhang, Weiwen Xu, Ying Shen, Wai Lam Aug 2024

Nonfactoid Question Answering As Query-Focused Summarization With Graph-Enhanced Multihop Inference, Yang Deng, Wenxuan Zhang, Weiwen Xu, Ying Shen, Wai Lam

Research Collection School Of Computing and Information Systems

Nonfactoid question answering (QA) is one of the most extensive yet challenging applications and research areas in natural language processing (NLP). Existing methods fall short of handling the long-distance and complex semantic relations between the question and the document sentences. In this work, we propose a novel query-focused summarization method, namely a graph-enhanced multihop query-focused summarizer (GMQS), to tackle the nonfactoid QA problem. Specifically, we leverage graph-enhanced reasoning techniques to elaborate the multihop inference process in nonfactoid QA. Three types of graphs with different semantic relations, namely semantic relevance, topical coherence, and coreference linking, are constructed for explicitly capturing the …


Beyond Automation: Ai As A Catalyst For New Job Creation In Software Development, Jill Willard, James Hutson Aug 2024

Beyond Automation: Ai As A Catalyst For New Job Creation In Software Development, Jill Willard, James Hutson

Faculty Scholarship

As artificial intelligence (AI) continues to evolve, its impact on software development and programming is profound, drawing parallels to the shift from assembler to object-oriented programming. This article explores how AI is reshaping the landscape of software jobs, creating new opportunities rather than diminishing them. By simplifying complex tasks and lowering barriers to coding, AI is expanding the technology "pie," introducing new use cases, and enhancing efficiency. The transition from monolithic services to microservices has reduced risks and accelerated deployment processes, and AI is poised to further this evolution by managing the complexities of service interactions through advanced orchestration layers. …


Observation Of Gravitational Waves From The Coalescence Of A 2.5–4.5 M⊙ Compact Object And A Neutron Star, A. Abac, R. Abbott, I. Abouelfettouh, F. Acernese, Teviet Creighton, Mario C. Diaz, Francisco Llamas, Soma Mukherjee, Volker Quetschke, Wenhui Wang Aug 2024

Observation Of Gravitational Waves From The Coalescence Of A 2.5–4.5 M⊙ Compact Object And A Neutron Star, A. Abac, R. Abbott, I. Abouelfettouh, F. Acernese, Teviet Creighton, Mario C. Diaz, Francisco Llamas, Soma Mukherjee, Volker Quetschke, Wenhui Wang

Physics and Astronomy Faculty Publications and Presentations

We report the observation of a coalescing compact binary with component masses 2.5–4.5 M⊙ and 1.2–2.0 M⊙ (all measurements quoted at the 90% credible level). The gravitational-wave signal GW230529_181500 was observed during the fourth observing run of the LIGO–Virgo–KAGRA detector network on 2023 May 29 by the LIGO Livingston observatory. The primary component of the source has a mass less than 5 M⊙ at 99% credibility. We cannot definitively determine from gravitational-wave data alone whether either component of the source is a neutron star or a black hole. However, given existing estimates of the maximum neutron star mass, we find …


Optimization Of Mass Spectrometry-Based Methods For Low-Input And Spatial Proteomics, Andikan Jones Nwosu Aug 2024

Optimization Of Mass Spectrometry-Based Methods For Low-Input And Spatial Proteomics, Andikan Jones Nwosu

Theses and Dissertations

Eukaryotic cells are highly heterogeneous. These cells are arranged into different compartments, carrying out separate functions and facilitating biological processes. Proteins are the effector biomolecules targeted to subcellular locations that help fulfill specific tasks in living organisms. Spatial proteomics can help unravel molecularly how protein abundance and localization are altered in cells, which is not feasible in traditional bulk-scale proteomics. To achieve this, our lab has developed a miniaturized sample processing platform called nanoPOTS, reduced separation columns' inner diameter to increase ionization efficiency and concentrate analytes for mass spectrometers and optimized data acquisition modes for increasing proteome coverage in spatial …