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Full-Text Articles in Social and Behavioral Sciences

Predicting E-Cigarette Use Among Emerging Adults Using Perceived Social Norms And Outcome Expectancies, Stephen N. Hanson May 2023

Predicting E-Cigarette Use Among Emerging Adults Using Perceived Social Norms And Outcome Expectancies, Stephen N. Hanson

Psychology Theses & Dissertations

Despite low rates of combustible tobacco use rates among adolescents and young adults, e-cigarettes continue to gain popularity. A few factors have been shown to be related to e-cigarette use based on prior research. One such example is social enhancement expectancies. Additionally, greater perceptions of harm have been found to be inversely related to e-cigarette use such that those that expect increased risk to their health are less likely to report using e-cigarettes. I hypothesized that social enhancement expectancies would mediate the relationship between perceptions of social norms and e-cigarette dependence. I also hypothesized that perceived harm, such as greater …


Relationships Between Healthcare Technology Experience, Acceptance, Attitudes, Self-Efficacy And Readiness In Pre-Licensure Nursing Students, Emily Lynne Boyce May 2023

Relationships Between Healthcare Technology Experience, Acceptance, Attitudes, Self-Efficacy And Readiness In Pre-Licensure Nursing Students, Emily Lynne Boyce

UNLV Theses, Dissertations, Professional Papers, and Capstones

Introduction: Technology is embedded in many aspects of healthcare. This is especially true in nursing, where technology is used daily in charting, medication administration, clinical decision-making, healthcare team communication, and information resource utilization. In nursing programs, students are exposed to healthcare technologies and expected to use them once entering the workforce. Healthcare technologies such as electronic health records (EHR), barcode medication administration, medication dispensing machines, and mobile technologies are critical to adopt to leverage their efficiencies and safety mechanisms to provide the best patient care. Despite evidence indicating the benefits of using healthcare technologies, new graduate nurses enter the workforce …


Occupational Therapy Fieldwork In An Emerging Justice-Based Setting: Hope For Prisoners, Noah Claypool May 2023

Occupational Therapy Fieldwork In An Emerging Justice-Based Setting: Hope For Prisoners, Noah Claypool

UNLV Theses, Dissertations, Professional Papers, and Capstones

This capstone occurred through a partnership with HOPE for Prisoners in Las Vegas, Nevada. As an emerging area of practice, the occupational therapy profession needs more resources and programs focused on the justice system. The lack of evidence-based resources to support future level I fieldwork students at HOPE for Prisoners poses a barrier for students to maximize their fieldwork experience and effectively engage with the organization’s population of incarcerated and formerly incarcerated men, women, and young adults in southern Nevada.This capstone experience involved a 14-week immersion at HOPE for Prisoners, including participation in training and workshops and engagement with clients, …


An Examination Of The Association Of Religiosity, Purity Culture, And Religious Trauma With Symptoms Of Depression And Anxiety, Kaelyn R. Griffin May 2023

An Examination Of The Association Of Religiosity, Purity Culture, And Religious Trauma With Symptoms Of Depression And Anxiety, Kaelyn R. Griffin

UNLV Theses, Dissertations, Professional Papers, and Capstones

While no consistent definition yet exists for religious trauma, religious abuse is typically defined as a misuse of authority by a spiritual leader to coerce, control, or exploit those under their leadership, which may in turn lead to the experience of religious trauma. Numerous studies suggest that experiencing abuse within a religious environment is a both global phenomenon and common experience. The impact of religious abuse has recently gained greater media attention, specifically related to the social and psychological impact of leaving high-cost religious groups (i.e., those with rigid rules or groups from which departure leads to isolation and rejection …


Increasing Foster Parent Awareness Of An Occupation-Based Approach To Child Well-Being, Taylar Hirte May 2023

Increasing Foster Parent Awareness Of An Occupation-Based Approach To Child Well-Being, Taylar Hirte

UNLV Theses, Dissertations, Professional Papers, and Capstones

Foster parents are an integral part of the child welfare system. They provide temporary care to children who otherwise cannot stay in their homes. They are required to be state or county licensed and each licensing agency has their own requirements including varying hours of training. The literature indicates foster parents do not receive enough training to feel prepared and confident to care for children with increased mental health, behavioral, school-related, cognitive, and peer relationship challenges that foster children often experience (AOTA, 2017; Lotty et al., 2020; Paul-Ward et al., 2014; Smith, 2022).The purpose of the present capstone project was …


Telehealth In Patients With Type 2 Diabetes Mellitus, Saghi Nassrouie May 2023

Telehealth In Patients With Type 2 Diabetes Mellitus, Saghi Nassrouie

UNLV Theses, Dissertations, Professional Papers, and Capstones

Description: Type 2 diabetes mellitus (DM2) is an epidemic that has many factors involved in its management to maintain control. Patients with DM2 require routine evaluations and blood work to provide comprehensive care. COVID-19 caused major shifts in traditional care which sparked an increase in the utilization of technology like telehealth. Telehealth can be an effective tool used to manage diabetes and help attain better glucose control, but its effectiveness during the COVID-19 pandemic warrants further investigation.Purpose: The purpose of this project was to determine if telehealth visits were more effective in reducing Hemoglobin A1c (HbA1c) in adult patients with …


Children’S Disclosure Of School Bullying: The Relation Between Peer Victimization, Internalizing Symptoms, Negative Affect, And Gender, Julia L. Kiefer May 2023

Children’S Disclosure Of School Bullying: The Relation Between Peer Victimization, Internalizing Symptoms, Negative Affect, And Gender, Julia L. Kiefer

Graduate Theses and Dissertations

Children who are bullied by their peers are at risk for several negative developmental outcomes and are therefore advised to tell an adult when they are. However, victims of school bullying are often reluctant to disclose to adults that they are being bullied. Some bullied children also experience symptoms of anxiety or depression, which could further reduce their likelihood of telling an adult. In this study, I tested the degree to which children’s internalizing symptoms predicted their likelihood of telling adults about being bullied at school, and if this relation was exacerbated by children’s negative feelings associated with telling an …


What Cognitive Processes Drive Attentional Bias, And How Does Stress Affect Them?, Colton L. Hunter May 2023

What Cognitive Processes Drive Attentional Bias, And How Does Stress Affect Them?, Colton L. Hunter

Graduate Theses and Dissertations

Attentional biases toward or away from emotionally evocative stimuli have been well documented and related to clinical outcomes such as social anxiety. Some work has suggested that stress modulates attentional biases, but there are a number of inconsistencies in this literature regarding the direction of that modulation, highlighting a need to examine moderators of that effect. Sex differences in stress effects could potentially explain this inconsistency, as acute stress can affect males and females differently. It is also possible that stress differentially influences multiple component processes underpinning attentional bias, but these processes have not been well character, and to date …


An Ecological Perspective Of American Rodent-Borne Orthohantavirus Surveillance, Nathaniel Mull May 2023

An Ecological Perspective Of American Rodent-Borne Orthohantavirus Surveillance, Nathaniel Mull

Graduate Theses and Dissertations

Orthohantaviruses are a global group of viruses found primarily in rodents, though several viruses have also been found in shrews and moles. Many rodent-borne orthohantaviruses are capable of causing one of several diseases in humans, and the mortality associated with these diseases ranges from < 0.1% - 50% depending on the specific etiological virus. In North and South America, orthohantavirus research was ignited by an outbreak of severe disease in the Four Corners region of the United States in 1993. However, despite the discovery of over 20 orthohantaviruses in the Americas, our understanding of orthohantavirus ecology and virus-host dynamics in this region is still limited, and orthohantavirus surveillance is generally restricted in scope to select regions and small portions of host distributional ranges. In Chapter I, I present a literature review on the current understanding of American rodent-borne orthohantavirus ecology. This review focused on under-studied orthohantaviruses, addressing gaps in knowledge by extrapolating information from well-studied orthohantaviruses, general rodent ecology, and occassionally from Eurasian orthohantavirus-host ecology. There were several key conclusions generated from this review that warrant further research: 1) the large number of putative orthohantaviruses and gaps in orthohantavirus evolution necessitate further surveillance and characterization, 2) orthohantavirus traits differ and are more generalizable based on host taxonomy rather than geography, and 3) orthohantavirus host species are disproportionately found in grasslands and disturbed habitats. In Chapter II, I present a prioritized list of rodent species to target for orthohantavirus surveillance based on predictive modeling using machine learning. Probable orthohantavirus hosts were predicted based on traits of known orthohantavirus hosts using two different types of evidence: RT-PCR and virus isolation. Predicted host distributions were also mapped to identify geographic hotspots to spatially guide future surveillance efforts. In Chapter III, I present a framework for understanding and predicting orthohantavirus traits based on reservoir host phylogeny, as opposed to the traditional geographic dichotomy used to group orthohantaviruses. This framework establishes three distinct orthohantavirus groups: murid-borne orthohantaviruses, arvicoline-borne orthohantaviruses, and non-arvicoline cricetid-borne orthohantaviruses, which differ in several key traits, including the human disease they cause, transmission routes, and virus-host fidelity. In Chapter IV, I compare rodent communities and orthohantavirus prevalence among grassland management regimes. Sites that were periodically burned had high rodent diversity and a high proportion of grassland species. However, rodent seroprevalence for orthohantavirus was also highest in burned sites, representing a trade-off in habitat management outcomes. The high seroprevalence in burned sites is likely due to the robust populations supported by the high quality habitat resulting from prescribed burning. In Chapters V and VI, I describe Ozark virus and Sager Creek virus, two novel orthohantaviruses discovered from specimens collected during Chapter IV. Both chapters report full genome sequences of the respective viruses and compare both nucleotide and protein phylogenies with related orthohantaviruses. Additionally in Chapter VI, I support the genetic analyses with molecular and ecological characterizations, including seasonal fluctuations in host abundance, correlates of prevalence, evidence of virus shedding, and information on host cell susceptibility to Sager Creek virus.


Daughters Of Depression : A Critical-Hermeneutic Phenomenological Examination Of Adult Black Women’S Experiences With Strong Black Woman’S Role When Mothered By Women With Perceived Depression, Christin D. Haynes May 2023

Daughters Of Depression : A Critical-Hermeneutic Phenomenological Examination Of Adult Black Women’S Experiences With Strong Black Woman’S Role When Mothered By Women With Perceived Depression, Christin D. Haynes

Theses, Dissertations and Culminating Projects

Black American women are experiencing chronic depression at alarming rates. Major racial/sex disparities in disease prevalence indicates Black American women are at increased risk for depression onset due to exposure to poverty and traumatic life events. With the rise of single, female-headed households, children are at increased risk for exposure to maternal mental illness which is defined as an adverse childhood experience impacting their development through adulthood. Black American mothers have the additional burden of racially socializing all children to learn how to manage systematic racist structures embedded in American society, yet daughters require the additional socialization for gender biases. …


Musculoskeletal Injury Concealment In The Reserve Officers’ Training Corps, Joshua D. Wooldridge May 2023

Musculoskeletal Injury Concealment In The Reserve Officers’ Training Corps, Joshua D. Wooldridge

UNLV Theses, Dissertations, Professional Papers, and Capstones

INTRODUCTION: Among service members, musculoskeletal injuries threaten military readiness and place a substantial burden on medical and financial resources. While musculoskeletal injuries (MSKIs) are a leading threat to military readiness, service members’ unwillingness to seek care constrains current prevention and surveillance efforts. A growing body of evidence shows US service members conceal a large proportion of injuries, especially in training environments. The Reserve Officers’ Training Corps is a critical training environment for future US military commissioned officers. Reserve Officers’ Training Corps (ROTC) is the largest commissioning source of new officers for the US military. ROTC cadets are college students concurrently …


Do Executive Functions Buffer Against Covid-19 Fear And Stress? A Latent Variable Approach, Tina Li Yi Ng, Nadyanna M. Majeed, Verity Yu Qing Lua, Andree Hartanto May 2023

Do Executive Functions Buffer Against Covid-19 Fear And Stress? A Latent Variable Approach, Tina Li Yi Ng, Nadyanna M. Majeed, Verity Yu Qing Lua, Andree Hartanto

Research Collection School of Social Sciences

Levels of COVID-19 stress have soared worldwide as a result of the pandemic. Given the pernicious psychological and physiological effects of stress, there is an urgent need for us to protect populations against the pandemic’s psychological impact. While there exists literature documenting the prevalence of COVID-19 stress among various populations, insufficient research has investigated psychological factors that might mitigate this worrying trend. To address this gap in the literature, the current study seeks to examine executive functions as a potential cognitive buffer against COVID-19 stress. To do so, the study adopted a latent variable approach to examine three latent factors …


The Effect Of Minority Stress On Sexual Minority College Students' Mental Health: The Role Of General Social Support And Sexuality-Specific Social Support, Lee A. Golembiewski May 2023

The Effect Of Minority Stress On Sexual Minority College Students' Mental Health: The Role Of General Social Support And Sexuality-Specific Social Support, Lee A. Golembiewski

Psychology Theses & Dissertations

Sexual minority (SM) college students continue to face greater mental health problems relative to their heterosexual peers (Woodford et al., 2014; Wilson & Liss, 2022). According to minority stress theory, SM individuals face distal (e.g., heterosexist discrimination) and proximal (e.g., expectations of rejection, internalized homophobia, and concealment) stressors related to their SM identity which can have negative effects on their mental health (Douglass & Conlin, 2020; Meyer, 2003). However, social support has been hypothesized to help protect against the effects of minority stress experienced by SM individuals (Cohen & Wills, 1985; Moody & Smith, 2013). Most of the existing research …


An Improvement Science Approach To Understanding Adaptive Leadership As A Tool For Diabetes Educators To Teach Patient Self-Efficacy, Allie Carter May 2023

An Improvement Science Approach To Understanding Adaptive Leadership As A Tool For Diabetes Educators To Teach Patient Self-Efficacy, Allie Carter

Dissertations

Background: Worldwide diabetes is estimated at 415 million, and that number is expected to increase to 642 million by 2040 (Roberts et al., 2017). Certified Diabetes Care and Educational Specialists (CDCES) and other health care providers strive to teach patients with diabetes skills that assist them in developing and maintaining self-efficacy. Current education methods are not always enough to help a patient navigate effects of their diabetes. Using the adaptive leadership principles can provide educators an interventional practice that facilitates patient self-management. This study explores the effectiveness of adaptive leadership when applied to the diabetes education delivery and confirms the …


Comprehensive Literature Review: Assessing The Impact Of Covid-19 Policies, School Closures And Social Distancing, On The Mental Health Of School Age Children, Fatuma A. Hassan May 2023

Comprehensive Literature Review: Assessing The Impact Of Covid-19 Policies, School Closures And Social Distancing, On The Mental Health Of School Age Children, Fatuma A. Hassan

Capstone Experience

Mental health is vital to the well-being of all individuals, especially children. COVID-19 unveiled a significant public health issue with poor mental health during the pandemic. There is limited literature about the mental health implications of COVID-19 policies for children and adolescents and preventive strategies for future pandemics. This comprehensive literature review seeks to further investigate the mental health impacts of school shutdowns and social distancing, which were nonpharmaceutical strategies, on school-aged children, 5-18 years old, and propose recommendations for public health officials to mitigate the mental health impacts for future pandemics. Additionally, the review aims to highlight the potential …


Program Evaluation: Utilizing Health Department’S Community Health Needs Assessment Data To Improve Emergency Preparedness Plans, Kathleen Gottschalk May 2023

Program Evaluation: Utilizing Health Department’S Community Health Needs Assessment Data To Improve Emergency Preparedness Plans, Kathleen Gottschalk

Capstone Experience

Public health officials conducting emergency response plans must know how to easily identify the vulnerable populations in their community or jurisdiction. It is beneficial for access and functional needs appendices to include information and resources directed at the identified vulnerable groups before an emergency event to improve health outcomes. Community Health Needs Assessments (CHNA) can provide population-level statistics and information needed to easily identify vulnerable or at-risk groups. This report aims to evaluate the use of the CHNA data to guide the development of inclusive emergency response plans that account for vulnerable populations in local health department jurisdictions. The 2021 …


National Cancer Control Plan Of The Korea: Current Status And The Fourth Plan (2021-2025), Kyu-Tae Han, Jae Kwan Jun, Jeong-Soo Im May 2023

National Cancer Control Plan Of The Korea: Current Status And The Fourth Plan (2021-2025), Kyu-Tae Han, Jae Kwan Jun, Jeong-Soo Im

Student and Faculty Publications

Cancer management has become a major policy goal for the government of the Korea. As such, the government introduced the National Cancer Control Plan (NCCP) to reduce the individual and social burdens caused by cancer and to promote national health. During the past 25 years, 3 phases of the NCCP have been completed. During this time, the NCCP has changed significantly in all aspects of cancer control from prevention to survival. The targets for cancer control are increasing, and although some blind spots remain, new demands are emerging. The government initiated the fourth NCCP in March 2021, with the vision …


Support For Social Workers Treating Adolescent Substance Abusers, Monica Delucia, Kethura Solano May 2023

Support For Social Workers Treating Adolescent Substance Abusers, Monica Delucia, Kethura Solano

Electronic Theses, Projects, and Dissertations

This study examines the barriers social workers experience when working with adolescent substance users. Research has not fully explored if intervention techniques are effective or suggest other approaches that may support substance use disorder professionals including supervisor support, training, and intervention. The purpose of this study was to evaluate if social workers who provide interventions to adolescent substance users have the adequate resources to be successful in their field. The literature review provides a better understanding of the common themes social workers experience when working with adolescent substance users.

This study used a qualitative design and interviewed 8 professional social …


Assessment Of The Knowledge, Attitude, And Practice Towards Expired Drug Disposal Among The Community In Beirut City, Lebanon, Nada Khansa, Azza A. K. Gazy, Abdalla El-Lakany, Souraya Domiati Apr 2023

Assessment Of The Knowledge, Attitude, And Practice Towards Expired Drug Disposal Among The Community In Beirut City, Lebanon, Nada Khansa, Azza A. K. Gazy, Abdalla El-Lakany, Souraya Domiati

BAU Journal - Health and Wellbeing

The global increase in pharmaceutical spending has led to enhanced international awareness of the unused and expired drug issues due to improper drug disposal's harmful economic, environmental, and health effects. Consequently, the study was conducted to assess the knowledge, attitude, and practice toward expired drug disposal among the community in Beirut City, Lebanon. A cross-sectional, observational, questionnaire-based study was conducted. Data were analyzed using SPSS version 23. The fact that improper disposal of expired medicine affects the environment and health was acknowledged by 70.7% of the 450 participants. Even though 72.2% of the participants knew that the best method for …


Meeting, Moving, Mastering - A Text Analysis Of The Aesthetic Attractions Of 'Wild Swimming', Dagmar Dahl, Åsa I. Bäckström Apr 2023

Meeting, Moving, Mastering - A Text Analysis Of The Aesthetic Attractions Of 'Wild Swimming', Dagmar Dahl, Åsa I. Bäckström

International Journal of Aquatic Research and Education

Why are people fascinated by swimming in nature? This article addresses the aesthetic experiences of wild swimming as expressed by five wild swimming authors in their books. Drawing from aesthetic philosophy, we analyze the ways in which the appeal of wild swimming is described on three levels: the allure of water in the environment, the sensory encounter between water and the body, and the experience of moving in water. Furthermore, with reference to Seel’s concept of nature aesthetics (1996), the experience of wild swimming is analyzed in terms of contemplation, correspondence, and imagination. We can conclude that the special intensity …


Ohio Forensic Nurse Examiners: Readiness To Care For Victims Of Sexual Assault With Disability, Deanna Nicole Smith Apr 2023

Ohio Forensic Nurse Examiners: Readiness To Care For Victims Of Sexual Assault With Disability, Deanna Nicole Smith

Doctor of Nursing Practice Scholarly Projects

Forensic nurse examiners (FNEs) care for crime victims in acute care settings. These nurses are specifically trained in trauma-informed care and evidence collection in cases of sexual assault, domestic violence, abuse, and human trafficking (RAINN, 2022). The scholarly project focuses on the care of victims of sexual assault living with disability, as this population is three times more likely to be victimized than any other population (NSVRC, 2022). The project literature review reveals a lack of data on preparation standards for FNEs on caring for victims with disability and providing accommodations during forensic examination. Currently, it is unknown if FNEs …


Aquatics For Individuals With Disabilities: An Analysis Of Publication Trends, Susan J. Grosse Apr 2023

Aquatics For Individuals With Disabilities: An Analysis Of Publication Trends, Susan J. Grosse

International Journal of Aquatic Research and Education

This study investigates the published literature in the field of aquatics with disabilities; more specifically, it examines literature published during the most recent two decades, 2000 through 2019. Considerations include the content focus of published articles relating to aquatics with disabilities, distribution of articles over the specified time period, publication opportunities for authors, barriers as well as enhancements to development of literature in the field, and summary recommendations.


Which Stroke Next? All Strokes Next! Part Two: Strokes For Intermediate And Advanced Swimmers, Robert Keig Stallman, Ebbe L. Horneman, Nils O. Vikander, Alexander Mwaipasi, Bente W. H. Laakso, Haakon - Paavo L. Nysted, Toni Ongala Apr 2023

Which Stroke Next? All Strokes Next! Part Two: Strokes For Intermediate And Advanced Swimmers, Robert Keig Stallman, Ebbe L. Horneman, Nils O. Vikander, Alexander Mwaipasi, Bente W. H. Laakso, Haakon - Paavo L. Nysted, Toni Ongala

International Journal of Aquatic Research and Education

The primary goal of this two-part project is to answer the rhetorical question of which strokes should be taught first, and which later (Langendorfer, 2013, Stallman, 2014a). As you have seen in Part One, we emphasize (as have many others) the need for a firm foundation before any stroke is introduced. When the learner is ready for propulsive motor competencies, there is no stroke which suits all as their first. In Part One we explored the “beginning strokes” all of which are candidates for any given learner’s first stroke. We also argued that after mastering their very first stroke the …


Rural Social Work Practice: Trauma-Focused Interventions Social Workers Use, Jose Carbajal Apr 2023

Rural Social Work Practice: Trauma-Focused Interventions Social Workers Use, Jose Carbajal

Journal of Human Services: Training, Research, and Practice

This research study examines rural social workers’ level of trauma knowledge and trauma treatment self-efficacy and the use of evidence-based interventions (CBT, TF-CBT, CPT, EMDR and PE). A retrospective design was used to examine Texas rural social workers’ use of evidence-based interventions. The Texas rural social worker sample (N=19) was extrapolated from a larger study (N=1007) conducted in 2014 examining Texas social workers’ trauma treatment and their use of evidence-based interventions. Descriptive and correlation statistical procedures were implemented to analyze the data for the current study. The results show social workers’ knowledge of trauma and treatment self-efficacy scores are above …


In This Issue (14:1), Stephen J. Langendorfer Ph.D. Apr 2023

In This Issue (14:1), Stephen J. Langendorfer Ph.D.

International Journal of Aquatic Research and Education

In This Issue 14:1 introduces and overviews the research and education articles and position statement associated with the first issue of the fourteenth volume of the International Journal of Aquatic Research and Education.


Ot Employment Program Addressing Homelessness For Women Experiencing Homelessness, Amber Hoffman, Susan Macdermott Apr 2023

Ot Employment Program Addressing Homelessness For Women Experiencing Homelessness, Amber Hoffman, Susan Macdermott

Spring 2023 Virtual OTD Capstone Symposium

Women experiencing homelessness face many barriers to employment participation. Occupational therapy (OT) is a well-suited profession to address employment barriers; however, there is a lack of OT programs that address the unique barriers to employment participation for women experiencing homelessness. The purpose of the capstone project was to develop a program focused on employment obtainment and maintenance for women experiencing homelessness. The employment program was developed based upon the findings from an in-depth literature review and needs assessment.


The Mental Health Epidemic In Veterinary Medicine: An Analysis Of Burnout In The Veterinary Field, Hannah Eckstein Apr 2023

The Mental Health Epidemic In Veterinary Medicine: An Analysis Of Burnout In The Veterinary Field, Hannah Eckstein

Undergraduate Theses

The Mayo Clinic describes burnout as a specific type of stress that involves a state of physical or emotional exhaustion. This exhaustion can lead to a lowered sense of accomplishment and negative personal identity. Despite burnout not being an actual diagnosis, many researchers believe there are several mental health components that contribute to burnout, such as depression and anxiety. Several factors are known to contribute to specifically work-related burnout, including lack of control, work-life imbalance, lack of social support, and extremes of the activity. All of the above factors relate to the veterinary field. In one study, 6.8% of male …


Genetic Loci Of Beta-Aminoisobutyric Acid Are Associated With Aging-Related Mild Cognitive Impairment, Einat Granot-Hershkovitz, Brian Spitzer, Yunju Yang, Wassim Tarraf, Bing Yu, Eric Boerwinkle, Myriam Fornage, Thomas H Mosley, Charles Decarli, Bruce S Kristal, Hector M González, Tamar Sofer Apr 2023

Genetic Loci Of Beta-Aminoisobutyric Acid Are Associated With Aging-Related Mild Cognitive Impairment, Einat Granot-Hershkovitz, Brian Spitzer, Yunju Yang, Wassim Tarraf, Bing Yu, Eric Boerwinkle, Myriam Fornage, Thomas H Mosley, Charles Decarli, Bruce S Kristal, Hector M González, Tamar Sofer

Student and Faculty Publications

We studied the genetic associations of a previously developed Metabolomic Risk Score (MRS) for Mild Cognitive Impairment (MCI) and beta-aminoisobutyric acid metabolite (BAIBA)-the metabolite highlighted by results from a genome-wide association study (GWAS) of the MCI-MRS, and assessed their association with MCI in datasets of diverse race/ethnicities. We first performed a GWAS for the MCI-MRS and BAIBA, in Hispanic/Latino adults (n = 3890) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). We identified ten independent genome-wide significant (p value <5 × 10-8) variants associated with MCI-MRS or BAIBA. Variants associated with the MCI-MRS are located in the Alanine-Glyoxylate Aminotransferase 2 (AGXT2 gene), which is known to be associated with BAIBA metabolism. Variants associated with BAIBA are located in the AGXT2 gene and in the SLC6A13 gene. Next, we tested the variants' association with MCI in independent datasets of n = 3178 HCHS/SOL older individuals, n = 3775 European Americans, and n = 1032 African Americans from the Atherosclerosis Risk In Communities (ARIC) study. Variants were considered associated with MCI if their p value <0.05 in the meta-analysis of the three datasets and their direction of association was consistent with expectation. Rs16899972 and rs37369 from the AGXT2 region were associated with MCI. Mediation analysis supported the mediation effect of BAIBA between the two genetic variants and MCI (p value = 0.004 for causal mediated effect). In summary, genetic variants in the AGXT2 region are associated with MCI in Hispanic/Latino, African, and European American populations in the USA, and their effect is likely mediated by changes in BAIBA levels.


Can Chatgpt Accurately Answer A Picot Question? Assessing Ai Respones To A Clinical Question, Candise Branum, Martin Schiavenato Apr 2023

Can Chatgpt Accurately Answer A Picot Question? Assessing Ai Respones To A Clinical Question, Candise Branum, Martin Schiavenato

Foley Library Scholarship

Background:

ChatGPT, an artificial intelligence (AI) text generator trained to predict correct words, can provide answers to questions but has shown mixed results in answering medical questions.

Purpose:

To assess the reliability and accuracy of ChatGPT in providing answers to a complex clinical question.

Methods:

A Population, Intervention, Comparison, Outcome, and Time (PICOT) formatted question was queried, along with a request for references. Full-text articles were reviewed to verify the accuracy of the evidence summary provided by the chatbot.

Results:

ChatGPT was unable to provide a certifiable response to a PICOT question. The references cited as evidence included incorrect journal …


Undergraduate Student Nurses’ Attitude Toward Mental Health Education: A Cross-Sectional Analysis, Abdulellah Modhi Alsolais, Benito Jr Nillo Areola, Amal Alfouzan, Marie Grace Mejia Nones, Talal Ali Alharbi Apr 2023

Undergraduate Student Nurses’ Attitude Toward Mental Health Education: A Cross-Sectional Analysis, Abdulellah Modhi Alsolais, Benito Jr Nillo Areola, Amal Alfouzan, Marie Grace Mejia Nones, Talal Ali Alharbi

Makara Journal of Health Research

Background: Reportedly, there has been a long-standing nursing shortage in Saudi Arabia. This study explored the attitudes of undergraduate student nurses considering them to be a factor contributing to this shortage. This study also investigated the association among gender, hospital exposures, and campus enrollment concerning mental health education.

Methods: Quantitative correlational analysis was used on 124 student nurses in mental health nursing. Using Point Binary, Spearman's rank and one-way ANOVA, significant determinants were correlated to the domains of mental health nursing.

Results: Student nurses have a positive attitude toward mental health education. Gender is significantly related to …