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Articles 631 - 660 of 38711
Full-Text Articles in Social and Behavioral Sciences
The Social Participation Development For Individuals With Unilateral And Bilateral Lower Extremity Amputation, Priscilla D. Omewah, Cassandra Nelson, Scott Love
The Social Participation Development For Individuals With Unilateral And Bilateral Lower Extremity Amputation, Priscilla D. Omewah, Cassandra Nelson, Scott Love
Spring 2024 Virtual OTD Capstone Symposium
This occupation-based program aims to help maintain and increase social participation for individuals with unilateral or bilateral lower extremity amputations. It was developed with an occupational therapy (OT) lens targeting adults with a lower limb amputation with a population of various ages (18-70), genders, and causes of injury to develop an occupation-based program with an OT focus. Individuals living with amputation often experience hardship when developing crucial ADL/IADL skills that can be vital for social participation regardless of age or cause of injury. This program focuses on developing social participation skills lost due to decreased functional mobility and skills caused …
Exploring Healthy Occupations For Adolescents At Risk For The Juvenile Justice System, Megan Vo, Dana Madalon, Mary Jan Greer
Exploring Healthy Occupations For Adolescents At Risk For The Juvenile Justice System, Megan Vo, Dana Madalon, Mary Jan Greer
Spring 2024 Virtual OTD Capstone Symposium
Many youth who are at risk for the juvenile justice system are likely to have spent some time in the foster care system or child welfare system. This population is often found lacking in social skills and/or life skills that contribute to the difficulties with independent living. Occupational therapy practitioners can provide independent life skills training, such as cooking/meal prepping, budgeting, and job exploration as well as providing healthy leisure outlets to promote a successful transition into adulthood. This program aims to promote the development of skills this population requires for successful independent living as an adult such as basic …
Ensnared Care: How Restrictive Healthcare Laws Impact Mothers, Mckenzie Richards
Ensnared Care: How Restrictive Healthcare Laws Impact Mothers, Mckenzie Richards
School of Public Policy Capstones
Do restrictive healthcare policies impact whether expectant mothers receive adequate prenatal care? Could such policies also affect access to alternative birthing options for delivery? Through a literature review and a two-way fixed effects model using panel data, this study investigates two categories of state-level restrictive healthcare policies: scope of practice laws and certificate of need laws. The literature demonstrates the detriments of scope of practice care on access to care and maternal health. However, the statistical models presented on scope of practice find no relationship between scope of practice laws and adequate prenatal care or alternative birthing options. Though the …
Volume 10 Full Text, Bjur Staff
Volume 10 Full Text, Bjur Staff
Butler Journal of Undergraduate Research
No abstract provided.
Stream Gauging: Investigating The Flow Rate And Residence Time In Laguna Bacalar, Mexico, Elizabeth J. Kowalczyk
Stream Gauging: Investigating The Flow Rate And Residence Time In Laguna Bacalar, Mexico, Elizabeth J. Kowalczyk
Butler Journal of Undergraduate Research
Stream gauging is a standard tool used to measure the flow rate of various bodies of water. Knowing the flow rate of a body of water allows for the residence time of a body of water to be calculated. Currently, there is very little information regarding the flow rate and residence times of Laguna Bacalar. This system has been observed hydrologically consistently only in the past 6 years. In this study, 13 stream-gauging locations of interest were identified and gauged for their respective flow rates using the midsection method. Once the flow rates were acquired, maps depicting the Laguna Bacalar …
Table Of Contents And Front Matter, Bjur Staff
Table Of Contents And Front Matter, Bjur Staff
Butler Journal of Undergraduate Research
No abstract provided.
Inter-Institutional Analysis Of Skin Of Color Representation In Dermatological Lecture Content At Md And Do Medical Schools, Oluwafunke Oluwatosin Ogunremi, Blake Fredericksen, John Komas, Sana Ismail, Siri Knutsen-Larson Md, Valeriy Kozmenko Md, Afia Albin Do
Inter-Institutional Analysis Of Skin Of Color Representation In Dermatological Lecture Content At Md And Do Medical Schools, Oluwafunke Oluwatosin Ogunremi, Blake Fredericksen, John Komas, Sana Ismail, Siri Knutsen-Larson Md, Valeriy Kozmenko Md, Afia Albin Do
Aesculapius Journal (Health Sciences & Medicine)
The purpose of this study was to analyze the lecture materials provided in medical schools through a diversity lens. Skin pathologies manifest distinctively on various shades of skin and physicians must be equipped with the proper knowledge to identify and diagnose these conditions accurately and promptly. For most medical students, images in prominent textbooks and lecture slides are their first encounter with disease presentations. Therefore, it is important to analyze the diversity of skin tones in the content that is being delivered. Specifically, the use of images featuring darker skin tones compared to those depicting lighter skin tones. This study …
Biomedical Text Readability After Hypernym Substitution With Fine-Tuned Large Language Models, Karl Swanson, Shuhan He, Josh Calvano, David Chen, Talar Telvizian, Lawrence Jiang, Paul Chong, Jacob Schwell, Gin Mak, Jarone Lee
Biomedical Text Readability After Hypernym Substitution With Fine-Tuned Large Language Models, Karl Swanson, Shuhan He, Josh Calvano, David Chen, Talar Telvizian, Lawrence Jiang, Paul Chong, Jacob Schwell, Gin Mak, Jarone Lee
SKMC Student Presentations and Publications
The advent of patient access to complex medical information online has highlighted the need for simplification of biomedical text to improve patient understanding and engagement in taking ownership of their health. However, comprehension of biomedical text remains a difficult task due to the need for domain-specific expertise. We aimed to study the simplification of biomedical text via large language models (LLMs) commonly used for general natural language processing tasks involve text comprehension, summarization, generation, and prediction of new text from prompts. Specifically, we finetuned three variants of large language models to perform substitutions of complex words and word phrases in …
Auditory Feedback Decreases Timing Variability For Discontinuous And Continuous Motor Tasks In Autistic Adults, Nicole M. Richard Williams, Luc Tremblay, Corene Hurt-Thaut, Jessica Brian, Julia Kowaleski, Kathrin Mertel, Sebastian Schlüter, Michael Thaut
Auditory Feedback Decreases Timing Variability For Discontinuous And Continuous Motor Tasks In Autistic Adults, Nicole M. Richard Williams, Luc Tremblay, Corene Hurt-Thaut, Jessica Brian, Julia Kowaleski, Kathrin Mertel, Sebastian Schlüter, Michael Thaut
Faculty Scholarship
Introduction: Autistic individuals demonstrate greater variability and timing error in their motor performance than neurotypical individuals, likely due at least in part to atypical cerebellar characteristics and connectivity. These motor difficulties may differentially affect discrete as opposed to continuous movements in autistic individuals. Augmented auditory feedback has the potential to aid motor timing and variability due to intact auditory-motor pathways in autism and high sensitivity in autistic individuals to auditory stimuli. Methods: This experiment investigated whether there were differences in timing accuracy and variability in autistic adults as a function of task (discontinuous vs. continuous movements) and condition (augmented auditory …
Informing Modifications To Social Participation And Navigation (Span) For Adolescents With Social Anxiety Incorporating Pet Dogs, Nicole Porter, Gary Bedell, Jason Getzler, Megan Mueller
Informing Modifications To Social Participation And Navigation (Span) For Adolescents With Social Anxiety Incorporating Pet Dogs, Nicole Porter, Gary Bedell, Jason Getzler, Megan Mueller
The Open Journal of Occupational Therapy
Background: Social anxiety is one of the most prevalent mental health challenges of adolescence and profoundly impacts social participation. This study obtained adolescent and parent feedback to inform a future modification of Social Navigation and Participation (SPAN) for use with adolescents with social anxiety incorporating pet dogs.
Methods: The study had two phases: Phase 1 included interviews with adolescents with social anxiety (n = 8) about their social participation experiences, strategies, pet dogs, and thoughts on a proposed intervention to promote social participation; and Phase 2 included on-line survey completed by the adolescents and their parents (n = 14) assessing …
Enhanced Breast Cancer Tumor Classification Using Mobilenetv2: A Detailed Exploration On Image Intensity, Error Mitigation, And Streamlit-Driven Real-Time Deployment, Aaditya Surya, Aditya Keshary Shah, Subash Tarun Sasikumar, Jarnell Kabore
Enhanced Breast Cancer Tumor Classification Using Mobilenetv2: A Detailed Exploration On Image Intensity, Error Mitigation, And Streamlit-Driven Real-Time Deployment, Aaditya Surya, Aditya Keshary Shah, Subash Tarun Sasikumar, Jarnell Kabore
Butler Journal of Undergraduate Research
This research introduces a sophisticated transfer learning model based on Google’s MobileNetV2 for breast cancer tumor classification into normal, benign, and malignant categories, utilizing a dataset of 1576 ultrasound images (265 normal, 891 benign, 420 malignant). The model achieves an accuracy of 0.82, precision of 0.83, recall of 0.81, ROC-AUC of 0.94, PR-AUC of 0.88, and MCC of 0.74. It examines image intensity distributions and misclassification errors, offering improvements for future applications. Addressing dataset imbalances, the study ensures a generalizable model. This work, using a dataset from Baheya Hospital, Cairo, Egypt, compiled by Walid Al- Dhabyani and colleagues (2020), emphasizes …
Peer-Mediated Family Support Project: Evaluation Of Changes In Family Quality Of Life, Preethy S. Samuel, Elizabeth Janks, Nia S. Anderson, Michael Bray, Christina Topolewski, Sharon Milberger
Peer-Mediated Family Support Project: Evaluation Of Changes In Family Quality Of Life, Preethy S. Samuel, Elizabeth Janks, Nia S. Anderson, Michael Bray, Christina Topolewski, Sharon Milberger
Developmental Disabilities Network Journal
The Family Quality of Life (FQOL) approach represents a paradigm shift from fixing to supporting people with intellectual/developmental disabilities (I/DD) by changing the focus from the individual to the family and highlighting strengths rather than deficiencies. Aging family caregivers of individuals with I/DD often encounter obstacles, including accessibility, acceptability, and affordability of services. Little is known about best practices to support aging families of adults with I/DD. Understanding how a state-wide peer-mediated family support project implemented in this study helped improve the FQOL of aging caregivers is important in broadening participation of other caregivers in these types of programs. To …
Interdisciplinary Treatment Approach To Youth With Intellectual Or Developmental Disabilities And Co-Occurring Mental Health Conditions, Ashley Greenwald, Erika Ryst, Diane D. Thorkildson, Lauren Brown
Interdisciplinary Treatment Approach To Youth With Intellectual Or Developmental Disabilities And Co-Occurring Mental Health Conditions, Ashley Greenwald, Erika Ryst, Diane D. Thorkildson, Lauren Brown
Developmental Disabilities Network Journal
Many individuals with Intellectual and/or Developmental Disabilities (IDD) have co-occurring mental health needs, yet service delivery options often do not allow for the integrated delivery of mental health treatment and social behavioral support services. Siloed treatment approaches often result in lack of collaboration between providers, increasing the difficulty in accessing comprehensive and coordinated treatments and reducing treatment potential and effective outcomes. Additionally, many service providers in behavioral support services are not trained to address significant mental health needs; similarly, providers of mental health services lack experience in modifying practices for differing cognitive needs. The lack of cross-training and cross-collaboration makes …
The Person Experiences Interview Survey: A Measure Addressing Ableism In Mental Healthcare For Patients With Intellectual And Developmental Disabilities, Micah Peace Urquilla
The Person Experiences Interview Survey: A Measure Addressing Ableism In Mental Healthcare For Patients With Intellectual And Developmental Disabilities, Micah Peace Urquilla
Developmental Disabilities Network Journal
Many People with Intellectual and Developmental Disabilities (IDD) also have mental health needs requiring the support of mental health service providers, yet they may experience barriers to full engagement in their care due to ableism. Ableism is a kind of prejudice that impacts People with IDD in many parts of life, even in mental health care. This article proposes how an adapted Patient Reported Experience Measure (PREM) can be a response to ableism, with an impact at three distinct yet interrelated levels that reflect the parties involved in the mental healthcare of People with IDD-MH: provider, caregiver, and patient.
At …
04-15-2024 Orsp Newsletter, Liz Williamson
04-15-2024 Orsp Newsletter, Liz Williamson
ORSP Newsletter
DMP Tool, Jeff Neal, new training module: Budget Basics, new policy Maligned Foreign Talent Recruitment
Exploring The Occupation Of Education Of Children With Undocumented Immigrant Parents, Denise Perez, Susan Macdermott, Jazminne Orozco Arteaga
Exploring The Occupation Of Education Of Children With Undocumented Immigrant Parents, Denise Perez, Susan Macdermott, Jazminne Orozco Arteaga
Spring 2024 Virtual OTD Capstone Symposium
This research study highlights the detrimental effects of family separations on children's well-being, academic performance, and long-term outcomes. It emphasizes the urgent need for research on the mental health effects of immigration policies on children at risk of parental deportation. A qualitative research study was used to understand the experiences and challenges of adults with undocumented immigrant parents during various stages of schooling. The research utilizes the Kawa model to explore emotional factors and barriers affecting students' occupational engagement in an educational setting. The study aims to identify supports and barriers to school engagement for students with undocumented immigrant parents, …
A New Lease On Life: The Occupational Impact Of Adaptive Skiing, Caitlin Tetherow, Amy Lyons-Brown, Amy Griswold
A New Lease On Life: The Occupational Impact Of Adaptive Skiing, Caitlin Tetherow, Amy Lyons-Brown, Amy Griswold
Spring 2024 Virtual OTD Capstone Symposium
This research study focuses on understanding the occupational impact of adaptive skiing on well-being and identity to promote lifelong occupational engagement, representation, and inclusion within current ski culture. A mixed-method research study utilized a 25-question online survey and an optional one-time virtual interview. 50 adaptive skiers and/or snowboarders participating in a winter adaptive program between 18-65 years old completed this study. This study found positive evidence supporting outcomes related to physical, emotional, spiritual, and social well-being and positive identity formation from adaptive skiing.
The Mental Health And Wellness Of Young Adults With Down Syndrome, Annika Soderfelt, Susan Macdermott, Jazminne Orozco Arteaga
The Mental Health And Wellness Of Young Adults With Down Syndrome, Annika Soderfelt, Susan Macdermott, Jazminne Orozco Arteaga
Spring 2024 Virtual OTD Capstone Symposium
A poster presentation regarding the mental health and wellness of young adults with Down syndrome. This poster discusses how the mental health and wellness needs of individuals with Down syndrome are or are not currently being met and how resources and programming could be created, particularly by OTs, to better meet their need.
An Exploration Of Pediatric Occupational Therapist's Perspectives On Functional And Assistive Mobility, Jennifer Allison, Amy Lyons-Brown
An Exploration Of Pediatric Occupational Therapist's Perspectives On Functional And Assistive Mobility, Jennifer Allison, Amy Lyons-Brown
Spring 2024 Virtual OTD Capstone Symposium
Background: Occupational therapists (OTs) are highly skilled in assessing context, environment, and sensory-motor needs which are critical in addressing functional mobility and implementing assistive mobility devices. There is limited research on pediatric OT’s role in functional mobility. This study aims to explore pediatric OT's roles and perceptions of functional mobility and the implementation and use of assistive mobility devices.
Methods: Data was collected via an online survey with an option to participate in a follow-up interview. Descriptive statistics and thematic analysis were used to summarize trends and differences in the data.
Results: Twenty licensed OTs working in a variety of …
Identifying Covariate-Related Subnetworks For Whole-Brain Connectome Analysis, Shuo Chen, Yuan Zhang, Qiong Wu, Chuan Bi, Peter Kochunov, L Elliot Hong
Identifying Covariate-Related Subnetworks For Whole-Brain Connectome Analysis, Shuo Chen, Yuan Zhang, Qiong Wu, Chuan Bi, Peter Kochunov, L Elliot Hong
Student and Faculty Publications
Whole-brain connectome data characterize the connections among distributed neural populations as a set of edges in a large network, and neuroscience research aims to systematically investigate associations between brain connectome and clinical or experimental conditions as covariates. A covariate is often related to a number of edges connecting multiple brain areas in an organized structure. However, in practice, neither the covariate-related edges nor the structure is known. Therefore, the understanding of underlying neural mechanisms relies on statistical methods that are capable of simultaneously identifying covariate-related connections and recognizing their network topological structures. The task can be challenging because of false-positive …
The Attitudes, Level Of Interest, And Knowledge Held By Physicians And Psychologists Toward Integrated Healthcare Practices And The Patient-Centered Medical Home Model, Mark Cassano, Robert A. Ditomasso, Barbara Golden, Scott D. Glassman
The Attitudes, Level Of Interest, And Knowledge Held By Physicians And Psychologists Toward Integrated Healthcare Practices And The Patient-Centered Medical Home Model, Mark Cassano, Robert A. Ditomasso, Barbara Golden, Scott D. Glassman
The Journal of Integrated Primary Care
As the healthcare system evolves, issues related to cost and access to care continue to persist. In response to this concern, integrated models of healthcare, like the Patient-Centered Medical Home (PCMH), have been developed to work toward reducing cost for both patients and providers, increasing patient access to quality care, and improving patients’ overall satisfaction with the care that they are provided. However, despite the overwhelming evidence found in the literature supporting the efficacy and benefit of these treatment models, it is unclear as to why more providers do not choose to practice and support collaborative forms of healthcare provision. …
Biopsychosocial Management Of Long Covid Fibromyalgia: Lessons From The Penn Medicine Lancaster General Health Fibromyalgia Program, Joseph Harrison, Dennis Given Psy.D.
Biopsychosocial Management Of Long Covid Fibromyalgia: Lessons From The Penn Medicine Lancaster General Health Fibromyalgia Program, Joseph Harrison, Dennis Given Psy.D.
The Journal of Integrated Primary Care
The COVID-19 pandemic has increased the prevalence of chronic health concerns worldwide, leading to a new population of patients suffering from Long Covid. Patients with Long Covid often experience persistent symptoms impacting multiple organ systems, including neuroimmune and neurological manifestations. Recently, attention has grown toward Long Covid patients developing chronic widespread pain similar to fibromyalgia. Fibromyalgia is a nociplastic pain disorder characterized by widespread pain and central sensitization with fatigue, sleep disturbances, and impairments in cognitive functioning. Given the nascent and limited research exploring new treatment options, patients need support now from biopsychosocial multi-modal pain management strategies. The Fibromyalgia Program …
An Exploration Of Self-Reported Training Needs For Anxiety Interventions Among Primary Care Behavioral Health Consultants, Katherine Buckheit, Ryan Willard, Kyle Possemato, Robyn Shepardson, Abigail Lashinsky, Jen Funderburk
An Exploration Of Self-Reported Training Needs For Anxiety Interventions Among Primary Care Behavioral Health Consultants, Katherine Buckheit, Ryan Willard, Kyle Possemato, Robyn Shepardson, Abigail Lashinsky, Jen Funderburk
The Journal of Integrated Primary Care
Introduction: Despite the need for greater training in evidence-based interventions for the treatment of anxiety in primary care behavioral health (PCBH), there are limited data on which interventions are desired by behavioral healthcare consultants (BHCs). The objective of this study was to identify which interventions BHCs desired more training in when treating anxiety in PCBH practice, and to examine if this preference was associated with theoretical orientation. Method: We conducted an online survey of PCBH providers regarding their training preferences for treatment of anxiety symptoms. The final sample comprised 291 BHCs recruited from e-mail listservs of national professional organizations. Providers …
Improving Dementia Symptoms Through Personalized Music, Lindsay Grainger
Improving Dementia Symptoms Through Personalized Music, Lindsay Grainger
SC Upstate Research Symposium
Alzheimer's disease and related dementia (ADRD) is a prevalent, costly, and complicated disease. With over 6 million Americans affected and the cost of treatment soaring to over $320 billion dollars annually, there is a growing need for low-cost interventions to treat symptoms. Routinely listening to personalized music selections has been shown to reduce agitation—the most common symptom of Alzheimer’s disease and related dementia. The purpose of this study was to provide a personalized music listening (PML) intervention of thirty minutes to 10 nursing home residents with dementia. Thirty-minute PML sessions occurred multiple times a week over six weeks. The inclusion …
Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk
Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk
SC Upstate Research Symposium
Purpose Statement: Several studies have shown that aerobic exercise can have a positive impact on alleviating symptoms experienced by individuals with Parkinson's disease (PD). Despite this evidence, the potential benefits of exercise for both PD patients and their care partners (PD dyad) remain unexplored. This research project investigates the effectiveness, therapeutic collaborations, and physical outcomes of a virtual reality (VR) tandem cycling program specifically designed for PD dyads.
Methods: Following approval from the Prisma Health Institutional Review Board, individuals with PD were identified and screened by clinical neurologists. The pre-testing measures for PD dyads (N=9) included emotional and cognitive status …
Gaza War: Too Many Citizens Being Killed, Sheraz Yaqub, Bjørn Edwin, Zane Hammoud, Gabriel Herrera-Almario, Buthaina Jabir, Kristoffer Lassen, Pål Dag Line, Miguel Angel Lopez-Gonzalez, Michael Puttick, Mohammed Ahmed Idrees Saadelnour, José Sampaio-Neto, Raghuram Sampath, Konstantin V. Sementsov, Ajith K. Siriwardena, Ernesto Sparrelid, Alberto Büge Stein, Robert Sutcliffe, Helena Taflin, Hany Takla, Silvio Valdec, Cherisse N. Vinoya, Waleed Zaid, Stephen J. Wigmore
Gaza War: Too Many Citizens Being Killed, Sheraz Yaqub, Bjørn Edwin, Zane Hammoud, Gabriel Herrera-Almario, Buthaina Jabir, Kristoffer Lassen, Pål Dag Line, Miguel Angel Lopez-Gonzalez, Michael Puttick, Mohammed Ahmed Idrees Saadelnour, José Sampaio-Neto, Raghuram Sampath, Konstantin V. Sementsov, Ajith K. Siriwardena, Ernesto Sparrelid, Alberto Büge Stein, Robert Sutcliffe, Helena Taflin, Hany Takla, Silvio Valdec, Cherisse N. Vinoya, Waleed Zaid, Stephen J. Wigmore
School of Dentistry Faculty Publications
No abstract provided.
Best Screening: Introducing The Neonatal Assessment Visual European Grid To Nicus In Tennessee, Gabrielle Sledge
Best Screening: Introducing The Neonatal Assessment Visual European Grid To Nicus In Tennessee, Gabrielle Sledge
OTD Capstone Projects
Blind Early Services Tennessee (BEST) is an early intervention agency that serves children ages 0-5 with visual impairments across Tennessee. BEST serves over 200 children and families across the state offering early intervention (BEST Start), parent empowerment (BEST Advocate), and family support (BEST Together) programming. The purpose of this project was to assist in the implementation of an early identification initiative (BEST Screening) using the Neonatal Assessment Visual European Grid (NAVEG). The NAVEG is a newborn vision screening shown to identify neurological risk for visual impairments. The long-term goal of this program is to promote the screening and early identification …
Childhood Cancer Survivorship: Navigating A New Normal In Middle Tennessee, Karli M. Beaumont
Childhood Cancer Survivorship: Navigating A New Normal In Middle Tennessee, Karli M. Beaumont
OTD Capstone Projects
Monroe Carell Jr. Children’s Hospital at Vanderbilt in partnership with Vanderbilt-Ingram Cancer Center offers REACH for Cancer Survivorship, a pediatric cancer survivorship clinic. REACH provides a full range of follow-up care designed to meet the physical, emotional, and practical needs of survivors and continuous surveillance of deleterious effects of cancer and its treatments. The purpose of this project was to meet population and agency needs through research of long- and late-term sequela while advocating for occupational therapy’s role in the oncology population through the proactive therapy and prospective surveillance models. The process of creating this project included synthesizing the literature, …
Mid-Term Outcome After Extracorporeal Life Support In Postcardiotomy Cardiogenic Shock: Recovery And Quality Of Life, Maja Hanuna, German Herz, Andre L. Stanzl, Yupeng Li, Christoph S Mueller, Christine E. Kamla, Clemens Scherer, Dietmar Wassilowsky, Gerd Juchem, Martin Orban, Sven Peterss, Christian Hagl, Dominik Joskowiak
Mid-Term Outcome After Extracorporeal Life Support In Postcardiotomy Cardiogenic Shock: Recovery And Quality Of Life, Maja Hanuna, German Herz, Andre L. Stanzl, Yupeng Li, Christoph S Mueller, Christine E. Kamla, Clemens Scherer, Dietmar Wassilowsky, Gerd Juchem, Martin Orban, Sven Peterss, Christian Hagl, Dominik Joskowiak
College of Humanities and Social Sciences Departmental Research
Background: Extracorporeal life support (ECLS) therapy for refractory postcardiotomy cardiogenic shock (rPCS) is associated with high early mortality rates. This study aimed to identify negative predictors of mid-term survival and to assess health-related quality of life (HRQoL) and recovery of the survivors. Methods: Between 2017 and 2020, 142 consecutive patients received ECLS therapy following cardiac surgery. The median age was 66.0 [57.0–73.0] years, 67.6% were male and the median EuroSCORE II was 10.5% [4.2–21.3]. In 48 patients, HRQoL was examined using the 36-Item Short Form Survey (SF-36) and the modified Rankin-Scale (mRS) at a median follow-up time of 2.2 [1.9–3.2] …
Serum Neuroactive Metabolites Of The Tryptophan Pathway In Patients With Acute Phase Of Affective Disorders, Yanli Li, Leilei Wang, Junchao Huang, Ping Zhang, Yanfang Zhou, Jinghui Tong, Wenjin Chen, Mengzhuang Gou, Baopeng Tian, Wei Li, Xingguang Luo, Li Tian, L Elliot Hong, Chiang-Shan R Li, Yunlong Tan
Serum Neuroactive Metabolites Of The Tryptophan Pathway In Patients With Acute Phase Of Affective Disorders, Yanli Li, Leilei Wang, Junchao Huang, Ping Zhang, Yanfang Zhou, Jinghui Tong, Wenjin Chen, Mengzhuang Gou, Baopeng Tian, Wei Li, Xingguang Luo, Li Tian, L Elliot Hong, Chiang-Shan R Li, Yunlong Tan
Student and Faculty Publications
BACKGROUND: Many studies showed disrupted tryptophan metabolism in patients with affective disorders. The aims of this study were to explore the differences in the metabolites of tryptophan pathway (TP) and the relationships between TP metabolites and clinical symptoms, therapeutic effect in patients with bipolar disorder with acute manic episode (BD-M), depressive episode (BD-D) and major depressive disorder (MDD).
METHODS: Patients with BD-M (n=52) and BD-D (n=39), MDD (n=48) and healthy controls (HCs, n=49) were enrolled. The serum neuroactive metabolites levels of the TP were measured by liquid chromatography-tandem mass spectrometry. Hamilton Depression Scale-17 item (HAMD-17) and Young Mania Rating Scale …