Social and Behavioral Sciences Commons^™

An Analysis Of Metabotropic Glutamate Receptors 2/3 And 5 In Schizophrenia, Major Depression And Bipolar Disorder From The Stanley Neuropathology Consortium, N Matosin, E Frank, F Fernandez, C Deng, J Wong, Xu-Feng Huang, K A. Newell

Xu-Feng Huang

Purpose: Metabotropic glutamate receptors (mGluRs) are proposed novel therapeutic targets for a variety of brain disorders such as schizophrenia (SZ), bipolar disorder (BP) and major depression (MD). Despite their potential, the involvement of these receptors in these pathological processes is uncertain. This information is crucial to understand the efficiency of drugs that target these receptors. Methods: Using post-mortem human brains, mGluR2/3 and mGluR5 binding densities were measured in the anterior cingulate cortex of SZ, BP, MD and matched controls (CT) (n=15/group) by receptor autoradiography. Results: Whilst preliminary analyses indicated no diagnostic effect in mGluR2/3 or mGluR5 binding densities, mGluR2/3 binding …

A Neuregulin 1 Transmembrane Domain Mutation Causes Imbalanced Glutamatergic And Dopaminergic Receptor Expression In Mice, K A. Newell, T Karl, Xu-Feng Huang

Xu-Feng Huang

The neuregulin 1 gene has repeatedly been identified as a susceptibility gene for schizophrenia, thus mice with genetic mutations in this gene offer a valuable tool for studying the role of neuregulin 1 in schizophrenia-related neurotransmission. In this study, slide-based receptor autoradiography was used to quantify glutamatergic N-methyl-d-aspartate (NMDA), dopaminergic D2, cannabinoid CB1 and acetylcholine M1/4 receptor levels in the brains of male heterozygous transmembrane domain neuregulin 1 mutant (Nrg1+/−) mice at two ages. Mutant mice expressed small but significant increases in NMDA receptor levels in the cingulate cortex (7%, p = 0.044), sensory cortex (8%, p = 0.024), and …

Alterations Of Mglur5 And Mglur5 Signaling Partners In Schizophrenia, Natalie Matosin, Martin Engel, Francesca Fernandez-Enright, Jeremy S. Lum, Jessica L. Andrews, Xu-Feng Huang, Kelly Newell

Xu-Feng Huang

No abstract provided.

Size And Shape Information Serve As Labels In The Alarm Calls Of Gunnison’S Prairie Dogs Cynomys Gunnisoni, C. N. Slobodchikoff, William R. Briggs, Patricia A. Dennis, Anne-Marie C. Hodge

Con Slobodchikoff, PhD

Some animals have the capacity to produce different alarm calls for terrestrial and aerial predators. However, it is not clear what cognitive processes are involved in generating these calls. One possibility is the position of the predator: Anything on the ground receives a terrestrial predator call, and anything in the air receives an aerial predator call. Another possibility is that animals are able to recognize the physical features of predators and incorporate those into their calls. As a way of elucidating which of these mechanisms plays a primary role in generating the structure of different calls, we performed two field …

Barrios-Lech_Linguistic_Interaction_Appendix_Four.Docx, Peter G. Barrios-Lech

Peter Barrios-Lech

Barrios-Lech_Linguistic_Interaction_Appendix_Five.Docx, Peter G. Barrios-Lech

Peter Barrios-Lech

Two Roads, One Destination: A Journey Of Discovery, Karen Joc, Peta J. Hopkins, Jessie Donaghey, Wendy Abbott

Wendy Abbott

The adoption of resource discovery platforms has been a growing trend in libraries. However, few libraries have reported on the transition from one discovery layer to another, and only a few institutions have discussed two discovery layers available in the same institution at the same time. Bond University Library recently implemented Alma as its library management system, and with this change a new discovery platform, Primo, was implemented to supersede the existing Summon platform. This paper presents the results of a usability study undertaken at Bond University Library in the move from one discovery layer to another.

Two Roads, One Destination: A Journey Of Discovery, Karen Joc, Peta J. Hopkins, Jessie Donaghey, Wendy Abbott

Wendy Abbott

The adoption of resource discovery platforms has been a growing trend in libraries. However, few libraries have reported on the transition from one discovery layer to another, and only a few institutions have discussed two discovery layers available in the same institution at the same time. Bond University Library recently implemented Alma as its library management system, and with this change a new discovery platform, Primo, was implemented to supersede the existing Summon platform. This paper presents the results of a usability study undertaken at Bond University Library in the move from one discovery layer to another.

Qualitative Assessment Of Animal Behaviour As An On-Farm Welfare-Monitoring Tool, Françoise Wemelsfelder, Alistair B. Lawrence

Françoise Wemelsfelder, PhD

There is a growing need to monitor the health and welfare of farm animals, and to develop methods which do so efficiently and reliably. A crucial problem with current methods is the integration of separate measurements taken during farm visits into accurate judgements of an animal’s overall welfare state. This paper proposes that the qualitative assessment of animal behaviour may serve as an integrative methodology which could guide the interpretation of other, more detailed welfare measurements. Recent research has demonstrated qualitative behaviour assessment to be reliable and repeatable under controlled experimental conditions. The paper concludes with a discussion of ways …

Qualitative Behavioural Assessment Of The Motivation For Feed In Sheep In Response To Altered Body Condition Score, C. A. Stockman, T. Collins, A. L. Barnes, D. Miller, S. L. Wickham, E. Verbeek, L. Matthews, D. Ferguson, F. Wemelsfelder, P. A. Fleming

Françoise Wemelsfelder, PhD

Qualitative behavioural assessment (QBA) has been used to quantify the expressive behaviour of animals, and operant tests have been used to quantify measures of behavioural need. In this study we compared measures of behavioural expression and behaviour in operant tests. We examined the behavioural expression of pregnant ewes of body condition score (BCS) 2 and 3. The ewes were exposed to a feed motivation test in which they received a food reward. Pregnant ewes (48–70 days gestation) were assessed during a food motivation test after they had been maintained at BCS 3 (n = 7) or given a decreasing plane …

The Scientific Validity Of Subjective Concepts In Models Of Animal Welfare, Françoise Wemelsfelder

Françoise Wemelsfelder, PhD

This paper takes a closer look at the subjectivity/objectivity relationship, as it plays a role in the science of animal welfare. It argues that subjective, experiential states in animals such as well-being and suffering are, contrary to what is often assumed, open to empirical observation and scientific assessment. The presumably purely private, inaccessible nature of such states is not an inherent property of these states, but derives from their misguided conception as ‘causal objects’ in mechanistic models of behaviour. This inevitably endows subjective experience with a ‘hidden’ status. However, subjective experience should be approached on its own conceptual grounds, i.e. …

Redeeming Innovation: Engaging Emerging Technologies By Rediscovering Our Roots, Ryan Ingersoll

Ryan Ingersoll

Speri-Paper-29-Dodd-Frank-From-Economic-Crisis-To-Regulatory-Reform.Pdf, Basak Kus

BASAK KUS

No abstract provided.

Socially Assistive Robots: Current Status And Future Prospects For Autism Interventions, Darlene Crone-Todd, Laurie A. Dickstein-Fischer, Ian M. Chapman, Ayesha T. Fathima, Gregory S. Fischer

Darlene Crone-Todd

Using Digital Commons To Support Digital Scholarship, Christy Edina Allen

Christy Allen

Police Integrity Lost Podcast Episode 29: Interview Of Phil Stinson On Vocal Minority Report, Philip M. Stinson

Philip M Stinson

This episode of the Police Integrity Lost podcast features an interview of Phil Stinson that was originally recorded for the Vocal Minority Report on May 24, 2016.

Quantitative And Qualitative Assessment Of The Response Of Foals To The Presence Of An Unfamiliar Human, Michela Minero, Maria Vittoria Tosi, Elisabetta Canali, Françoise Wemelsfelder

Françoise Wemelsfelder, PhD

This work aimed to apply a combined qualitative and quantitative approach to the interpretation of an on-farm behaviour test for horses, and to examine whether 1 month of handling would affect the response of yearlings to an unfamiliar stationary human in their home environment. Throughout a 1-month period, 14 Thoroughbred Yearlings (16 ± 0.22 months old) that had formerly experienced minimal contact with humans, were handled daily for about 45 min. The yearlings were tested twice, just before and just after the handling period. The behaviour of the horses during the tests was both video-recorded and directly recorded by the …

Inter-Observer Reliability Of Qualitative Behavioural Assessments Of Sheep, Clare Phythian, Eleni Michalopoulou, Jennifer Duncan, Françoise Wemelsfelder

Françoise Wemelsfelder, PhD

Qualitative Behaviour Assessment (QBA) is whole-animal methodology that assesses the expressive qualities of animal demeanour using descriptors such as ‘relaxed’, ‘anxious’ or ‘content’. This study aimed to examine the inter-observer reliability of 12 fixed-list QBA descriptors for sheep that had been generated in a previous Free-Choice Profiling study by experienced animal welfare inspectors, based on the same video footage used in the current study. The 12 QBA terms were scored by two different assessor groups consisting of two veterinary science students and four veterinary surgeons (Group 1), and seven farm assurance inspectors (Group 2). The two assessor groups met and …

Flooring And Driving Conditions During Road Transport Influence The Behavioural Expression Of Cattle, Catherine A. Stockman, Teresa Collins, Anne L. Barnes, David Miller, Sarah L. Wickham, David T. Beatty, Dominique Blache, Françoise Wemelsfelder, Patricia A. Fleming

Françoise Wemelsfelder, PhD

This study examined whether observers could distinguish between cattle that were exposed to various road transport conditions: Experiment 1 compared a manipulated flooring treatment (non-grip flooring, NG) with a control transport event (grip flooring, G) and Experiment 2 compared a manipulated driving style (stop-start driving, SS) with a control transport event of smooth, continuous (C) driving. The behavioural expression of cattle was assessed through the process of Qualitative Behavioural Assessment (QBA), and these assessments were tested for correlation with various physiological parameters. Fourteen Angus steers were assessed. Blood samples were collected immediately before and after transport, and heart rate and …

The Qualitative Assessment Of Responsiveness To Environmental Challenge In Horses And Ponies, Fabio Napolitano, Giuseppe De Rosa, Ada Braghieri, Fernando Grasso, Aldo Bordi, Françoise Wemelsfelder

Françoise Wemelsfelder, PhD

The responsiveness of 10 horses and 10 ponies to environmental challenge (represented by an open field test) was assessed using a qualitative approach based on free choice profiling methodology (FCP), which gives observers complete freedom to choose their own descriptive terms. Data were analysed with generalised Procrustes analysis (GPA), a multivariate statistical technique associated with FCP. A cross-validation of the outcomes of this approach to data recorded through quantitative behaviour analysis, and through a questionnaire given to the animals’ owner/riding instructor, was also performed using principal component analysis (PCA). Twelve undergraduate students generated their own descriptive vocabularies, by watching 20 …

Immigration, Employment Opportunities, And Criminal Behavior, Matthew Freedman, Emily Owens, Sarah Bohn

Matthew Freedman

Immigration, Employment Opportunities, And Criminal Behavior [Online Appendix], Matthew Freedman, Emily Owens, Sarah Bohn

Matthew Freedman

Supplemental Materials For Building Data And Information Literacy In The Undergraduate Chemistry Curriculum, Yasmeen Shorish, Barbara A. Reisner

Yasmeen Shorish

Course syllabus from Chem 481, Fall 2015, to supplement the chapter "Building Data and Information Literacy in the Undergraduate Chemistry Curriculum" in the monograph Integrating Library and Information Literacy Into Chemistry Curricula - ACS Symposium Series, ACS Publications.

Qualitative Behavioural Assessment And Quantitative Physiological Measurement Of Cattle Naïve And Habituated To Road Transport, C. A. Stockman, T. Collins, A. L. Barnes, D. Miller, S. L. Wickham, D. T. Beatty, D. Blache, F. Wemelsfelder, P. A. Fleming

Françoise Wemelsfelder, PhD

The present study examined whether observers could distinguish between cattle that are naïve to road transport and the same cattle after becoming more habituated to transport. The behavioural expression of cattle was assessed through the method of qualitative behavioural assessment (QBA), and these assessments were correlated with various physiological parameters. Fourteen Angus steers were assessed during their first road trip and then again on their ninth trip, 15 days later. Blood samples were collected immediately before and after transport, and heart rate and core body temperature were measured continuously throughout each trip. Video footage recorded during each trip was edited …

How Animals Communicate Quality Of Life: The Qualitative Assessment Of Behaviour, F. Wemelsfelder

Françoise Wemelsfelder, PhD

The notion ‘quality of life’ (QoL) suggests that welfare in animals encompasses more than just an absence of suffering; it concerns the quality of an animal’s entire relationship with its environment, of how it lives its life. Judgements of such quality are based on the integration of perceived details of how animals behave over time in different contexts. The scientific status of such judgements has long been ambiguous, but in recent decades has begun to be addressed by animal scientists. This paper starts with a brief review of qualitative approaches to the study of animal behaviour, which tend to address …

Life In Captivity: Its Lack Of Opportunities For Variable Behaviour, Françoise Wemelsfelder

Françoise Wemelsfelder, PhD

No abstract provided.

Experience In Substrate-Enriched And Substrate-Impoverished Environments Affects Behaviour Of Pigs In A T-Maze Task, Michael Mendl, Hans W. Erhard, Marie Haskell, Françoise Wemelsfelder, Alistair B. Lawrence

Françoise Wemelsfelder, PhD

Previous research showed that pigs reared in substrate-impoverished conditions performed a smaller proportion of their total behavioural repertoire in their home pens (showed lower behavioural diversity), than pigs reared in substrate-enriched conditions. This study examined whether these differences were the result of fundamental changes in behavioural organisation. A T-maze task was used to test the hypothesis that substrate-impoverished pigs are prone to develop fixed, unvarying behaviour which may underlie their reduced behavioural diversity. They were predicted to be poorer at reversing previous response patterns in the maze, and less able to alter their behaviour in response to a novel (distracting) …

Pathways To Open Access : The Story Of An Institutional Repository And How We Built It., Dwayne Buttler, Rachel Howard, Sarah Frankel

Sarah Frankel

The central purpose of an institutional repository (IR) is providing open access to scholarship. That scholarship originates primarily through the work of faculty and students at research institutions, leading research libraries to embrace IRs and the scholarly communication movement. IRs typically include student theses and dissertations and faculty publications but sometimes extend far beyond to institutional records and documents. Launching an IR requires significant collaborative work across disparate specialties and institutional structures to establish policies, workflows, configure metadata and technology for retrieval, and fashion outreach and ongoing support to the administrators and ultimately provide mediated support to the scholars who …

Speculation And Price Indeterminacy In Financial Markets, Shyam Sunder

Shyam Sunder

No abstract provided.

Desert Or Oasis: Reflecting On Teaching And Tweaking A Discovery Layer., Vera J. Lux, Amy F. Fyn, Robert J. Snyder

Vera J Lux