Social and Behavioral Sciences Commons^™

Closed Head Injury In An Age-Related Alzheimer Mouse Model Leads To An Altered Neuroinflammatory Response And Persistent Cognitive Impairment, Scott J. Webster, Linda J. Van Eldik, D. Martin Watterson, Adam D. Bachstetter

Sanders-Brown Center on Aging Faculty Publications

Epidemiological studies have associated increased risk of Alzheimer's disease (AD)-related clinical symptoms with a medical history of head injury. Currently, little is known about pathophysiology mechanisms linked to this association. Persistent neuroinflammation is one outcome observed in patients after a single head injury. Neuroinflammation is also present early in relevant brain regions during AD pathology progression. In addition, previous mechanistic studies in animal models link neuroinflammation as a contributor to neuropathology and cognitive impairment in traumatic brain injury (TBI) or AD-related models. Therefore, we explored the potential interplay of neuroinflammatory responses in TBI and AD by analysis of the temporal …

A Measure Of The Economic Impact Of Keeneland Racing And Sales On Lexington-Fayette County, Christopher R. Bollinger

CBER Research Report

Keeneland is an important Lexington Institution. This report shows that Keeneland draws individuals into Fayette County who spend money not only at Keeneland but in the city itself. We measure the economic impact of this spending on the local economy. For our initial study, we considered spending by patrons at the 2014 Fall Meet, the September Yearling Sale and the November Breeding Stock Sale. Based upon these findings, we were also able to assess the impact of the Spring Race Meeting, January Horses of All Ages Sale and the April Two-Year-Olds in Training Sale.

Many Hands Make Light Work: Name Authority Cooperative Program (Naco) Training At University Of Kentucky Libraries, Julene L. Jones

Library Presentations

Authority control, or the maintenance of consistent access points throughout a catalog, may not be the most exciting topic in the library world, but is increasing in importance as metadata schemas evolve and linked data applications emerge. UK has developed multiple strategies for maintaining its catalog's authority control, and, most recently, has undertaken NACO training!

Upgrade Your View Of The Web With Browser Extensions, Kathryn Lybarger

Library Presentations

If there are web sites you use frequently, you may be able to improve your (and your patrons') interactions with them using browser extensions; this can often be done without having special access to that web site, and even without admin permissions on your computer. In this session, I'll describe a few types of browser extensions (including custom OpenSearch search boxes and Greasemonkey/Tampermonkey user scripts), and how I have used them with our OPAC and other web sites.

Attenuation Of Traumatic Brain Injury-Induced Cognitive Impairment In Mice By Targeting Increased Cytokine Levels With A Small Molecule Experimental Therapeutic, Adam D. Bachstetter, Scott J. Webster, Danielle S. Goulding, Jonathan E. Morton, D. Martin Watterson, Linda J. Van Eldik

Sanders-Brown Center on Aging Faculty Publications

BACKGROUND: Evidence from clinical studies and preclinical animal models suggests that proinflammatory cytokine overproduction is a potential driving force for pathology progression in traumatic brain injury (TBI). This raises the possibility that selective targeting of the overactive cytokine response, a component of the neuroinflammation that contributes to neuronal dysfunction, may be a useful therapeutic approach. MW151 is a CNS-penetrant, small molecule experimental therapeutic that selectively restores injury- or disease-induced overproduction of proinflammatory cytokines towards homeostasis. We previously reported that MW151 administered post-injury (p.i.) is efficacious in a closed head injury (CHI) model of diffuse TBI in mice. Here we test …

Perceptions Of School And Health Department Emergency Preparedness Collaboration, Kaitlin A. O'Keefe, Katharine D. Arrington, Michael Prelip, Kimberley I. Shoaf

Frontiers in Public Health Services and Systems Research

Background: School systems often have the vital responsibility of protecting students during emergency situations. Collaborations with the local health department (LHD) can be invaluable in helping schools effectively fulfill this responsibility.

Purpose: An evaluation of existing organizational collaborations is needed to describe attitudes toward current efforts and to form recommendations for enhancing the effectiveness of future joint programs.

Methods: Questionnaires regarding perceptions of existing collaborations were distributed to a sample of LHDs and schools districts in spring and summer 2011. Participant responses from each organization were paired on jurisdictional area, forming 25 paired observations. Analyses were conducted in …

Letter From The Editor, James Bohland, Cassidy Henry

Ex-Patt Magazine

No abstract provided.

Southeastern Law Librarian Spring 2015, Seaall

Newsletters

No abstract provided.

How The Commons Was Changed: Politics, Ecology, And The History Of Floodplain Institutions, Lisa Cliggett

Anthropology Faculty Publications

A review of The Contested Floodplain: Institutional Change of the Commons in the Kafue Flats, Zambia. By Tobias Haller. Lanham, Maryland: Lexington Books, 2013.

Religious Extremism And Sectarian Violence: The Rise Of Isis, Jordan Haven

Ex-Patt Magazine

How has the Islamic State of Iraq and the Levant (also known as IS, ISIS, or ISIL) managed to take over such a large swath of territory in the Middle East?

The F-35: Putting Rma Theory To The Test, Alexander Melynkovych

Ex-Patt Magazine

Will history judge the F-35 as a success or failure? Putting RMA Theory to the test.

Trouble In The Family, Travis Cady

Ex-Patt Magazine

Europe is experiencing separatism - is there trouble in the family?

How The Commons Was Changed: Politics, Ecology, And The History Of Floodplain Institutions, Lisa Cliggett

Lisa Cliggett

No abstract provided.

The Future Of Sino-Russian Cooperation: A Rough Road Ahead, Cassidy Henry

Ex-Patt Magazine

After spending two semesters on the Chinese-Russian border, Henry reflects on the future of Sino-Russian relations and whether the West should worry.

The Decision To Invade: Stalin In 1950, Elliot Estebo

Ex-Patt Magazine

Examining the past and recently discovered Soviet-Era documents to determine how Stalin came to the decision to invade.

Influx: Why Everyone Benefits From Migration, Ethan Rutledge

Ex-Patt Magazine

Ex-Patt editor Ethan Rutledge reviews Paul Collier’s most recent book.

Unbridled Spirit: A Foreigner In The Bluegrass, Mirgul Karimova

Ex-Patt Magazine

A Fulbright Scholar reflects on her time at the Patterson School and in the Bluegrass.

Geographic Variation In The Delivery Of Public Health Services: Understanding Causes And Consequences, Glen P. Mays

Health Management and Policy Presentations

The implementation and reach of evidence-based prevention and public health programs varies widely across the U.S., as does the availability of cross-cutting infrastructure and foundational capabilities required to support these interventions. This talk profiles ongoing research to uncover the causes and consequences of variation in public health delivery. This research points to policy and administrative strategies that can reduce inequities and inefficiencies in public health protections.

The Sleeping Giant Wants A Veto, Elizabeth Suparmanto

Ex-Patt Magazine

The sleeping giant wants a veto. Will Brazil be able to convince the world it deserves a permanent seat?

High Yield From Small Change: Evolution In Response To User Need, Beth Reeder, Melinda Borie

Library Presentations

Renovation can be daunting, but it does not have to happen all at once. Improvement can come as the result of a series of incremental changes. This poster session chronicles the transformation of collection areas into much-needed meeting and library instruction space.

Kentucky Digital Newspaper Program, Kopana Terry

Library Presentations

No abstract provided.

Answering The Call To Integrate: Simple Strategies From Public Health And Healthcare Executives In One Urban County, Erik L. Carlton, Paul C. Erwin

Frontiers in Public Health Services and Systems Research

Background: As the Affordable Care Act transforms the practice of both public health and health care, it also provides opportunity for both to become more closely linked through improved integration and collaboration. Yet, while public health agencies are increasingly called to work with healthcare partners to address population health needs, both public health leaders and their healthcare counterparts may not be well equipped to answer that call. Although recent studies have begun exploring the collaborative strategies and capacity of public health system partners, there is still much to learn. The purpose of this study was to identify, through the perspective …

Accreditation Intent, Community Health Assessments, And Local Health Department–Hospital Collaboration, Erik L. Carlton, Simone Singh

Frontiers in Public Health Services and Systems Research

Background: Community health assessments (CHAs) are among the most core of activities conducted by local health departments (LHDs), and many LHDs have been conducting CHAs on a regular basis for years. More recently, completing a CHA has also become a prerequisite for LHDs seeking accreditation by the Public Health Accreditation Board (PHAB). Similarly, under the Affordable Care Act, tax-exempt hospitals are required to conduct periodic community health needs assessments. Opportunities thus exist for LHDs and tax-exempt hospitals to engage in collaborations related to CHAs. Yet, it remains unclear whether interest in PHAB accreditation provides incentive to LHDs to engage in …

Better Engaging Communities: Moving Beyond Cardinal Rules, Anna G. Hoover

Anna G. Hoover

“Cardinal rules” and best practice approaches have guided governmental risk communication efforts at chronic risk sites for more than two decades, playing an important role in how those most affected by contamination make sense of risk. In addition to providing information, however, communication approaches themselves can affect community perceptions indirectly, through stakeholder interpretations of the processes by which risk information is shared. It is increasingly necessary to evaluate not only whether risk communication approaches have been effective for increasing knowledge but if, in fact, the ways in which information is shared has had unintended consequences that change how stakeholders perceive …

Refining And Improving The Methodology For The National Health Security Preparedness Index, Glen P. Mays

Health Management and Policy Presentations

This first meeting of two newly reconstituted Working Groups for the National Health Security Preparedness Index Program examined opportunities for improving and refining the Index's measurement, scaling, weighting, and aggregation methodologies. Methodological improvements will enhance the Index's utility for education, planning, policy development, and quality improvement efforts focused on improving national preparedness and resiliency for large-scale health threats.

Unlocking The Mysteries Of Tdp-43, Keith A. Josephs, Peter T. Nelson

Sanders-Brown Center on Aging Faculty Publications

No abstract provided.

Brief Report: Evidence Of Ingroup Bias On The Shooter Task In A Saudi Sample, Timothy P. Schofield, Timothy Deckman, Christopher P. Garris, C. Nathan Dewall, Thomas F. Denson

Psychology Faculty Publications

When predominantly White participants in Western countries are asked to shoot individuals in a computer game who may carry weapons, they show a greater bias to shoot at outgroup members and people stereotyped as dangerous. The goal was to determine the extent to which shooter biases in the Middle East would vary as a function of target ethnicity and culturally appropriate or inappropriate headgear. Within a sample of 37 male Saudi Arabian residents, we examined shooter biases outside of Western nations for the first time. Targets in this task were either White or Middle Eastern in appearance, and wore either …

A Practical Algorithm For Managing Alzheimer's Disease: What, When, And Why?, Jeffrey L. Cummings, Richard S. Isaacson, Frederick A. Schmitt, Drew M. Velting

Sanders-Brown Center on Aging Faculty Publications

Alzheimer's disease (AD) is the most common form of dementia and its prevalence is increasing. Recent developments in AD management provide improved ways of supporting patients and their caregivers throughout the disease continuum. Managing cardiovascular risk factors, maintaining an active lifestyle (with regular physical, mental and social activity) and following a Mediterranean diet appear to reduce AD risk and may slow cognitive decline. Pharmacologic therapy for AD should be initiated upon diagnosis. All of the currently available cholinesterase inhibitors (ChEIs; donepezil, galantamine, and rivastigmine) are indicated for mild-to-moderate AD. Donepezil (10 and 23 mg/day) and rivastigmine transdermal patch (13.3 mg/24 …

Variables Related To School Media Center Lgbt Collections, Shannon M. Oltmann

Information Science Faculty Publications

The inclusion of LGBT (lesbian, gay, bisexual, and transgender) literature in school media centers can be controversial, but such material can be beneficial in helping LGBT students come to terms with their sexuality and with helping to foster understanding in non-LGBT students. To examine the extent of such collections in school media centers, this research conducted a checklist exercise to examine the holdings of school libraries in two very different states, one in the northeastern United States and one in the southern United States. The study examined variables that may correlate with the number of LGBT books available in the …

It Starts With A Good Idea: Funded Research 101, Mary H. Molinaro

Library Presentations

No abstract provided.