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Full-Text Articles in Social and Behavioral Sciences

Environmental Governance In The Carbon Economy: Regulating Greenhouse Gas Emissions In California's Cap-And-Trade Program, Patrick M. Bigger Jan 2015

Environmental Governance In The Carbon Economy: Regulating Greenhouse Gas Emissions In California's Cap-And-Trade Program, Patrick M. Bigger

Theses and Dissertations--Geography

Since 2006 California has been pursuing the most ambitious climate change policy in the United States, implementing a suite of greenhouse gas reduction measures ranging from automobile refrigerant disposal rules to clean energy standards for electric power utilities. The most significant of these measures is the creation of a cap‐and‐trade program. Through this program, regulators seek to create a knowable price‐signal to incentivize emissions reductions among polluters. Using a suite of ethnographic methods, this dissertation looks at the people, ideas, and institutions that have been mobilized in the creation of California’s cap‐and‐ trade program.

Substantively, the dissertation engages with three …


Should We Stay Or Should We Go?: A Study Of Indian It Migrants In Raleigh-Durham, North Carolina: Deciding To Stay In The United States Or Return To India, Andrew Robert Patrick Ashley Jan 2015

Should We Stay Or Should We Go?: A Study Of Indian It Migrants In Raleigh-Durham, North Carolina: Deciding To Stay In The United States Or Return To India, Andrew Robert Patrick Ashley

Theses and Dissertations--Geography

Over the past two decades, an increasing number of IT professionals from India have been migrating to the United States on temporary H-1B or F-1 visas. This thesis offers a case study to address how migrants on such temporary visas decide whether to seek further residency in the United States or return to India. Based on interviews conducted in 2013 and 2014 in the Raleigh-Durham area of North Carolina, I examine the factors migrants consider, as well as how the struggles presented through the visa programs may effect these considerations. I also analyze how mass migration from India has changed …


Rediscovery Of A Native American Cultural Landscape: The Chickasaw Homeland At Removal, Michael D. Walls Jan 2015

Rediscovery Of A Native American Cultural Landscape: The Chickasaw Homeland At Removal, Michael D. Walls

Theses and Dissertations--Geography

Little information beyond generalities exists regarding the cultural landscape of the Chickasaw Indians in their ancestral homelands prior to Removal in the late 1830s. This dissertation evaluates one possible archival source for specifics of Chickasaw land use, the field notes and survey plats compiled as part of the Public Land Survey System (PLSS). The process of original survey following land cession treaty divided the ceded area up into the familiar square-mile rectangular system of townships and ranges that extends from the Mississippi Territory westwards, in the so-called public land states.

The research compiles all cultural observations made by the surveyors …


When Security Dominates The Agenda: The Influence Of Interstate Rivalry On Women's Status, Theresa Schroeder Jan 2015

When Security Dominates The Agenda: The Influence Of Interstate Rivalry On Women's Status, Theresa Schroeder

Theses and Dissertations--Political Science

The overarching theme of my dissertation is the effect of interstate rivalries on women’s status. Specifically, I investigate the influence of rivalries on the election of women, the adoption of a gender quota, and the overall level of gender equality. National security is a prime concern in states involved in an interstate rivalry, which can influence women’s lives in a number of key ways. Through the actions of individual voters and rational parties, I find that being in an interstate rivalry leads to lower levels of female representation. In addition, I theorize that rivalries lessen societal pressure to increase female …


Three Essays On The Economic Impact Of Immigration, James Sharpe Jan 2015

Three Essays On The Economic Impact Of Immigration, James Sharpe

Theses and Dissertations--Economics

With the significant rise in immigration to the U.S. over the last few decades, fully understanding the economic impact of immigration is paramount for policy makers. As such, this dissertation consists of three empirical essays contributing to the literature on the impact of immigration. In my first essay, I re-examine the impact of immigration on housing rents and completely controlling for endogenous location choices of immigrants. I model rents as a function of both contemporaneous and initial economic and housing market conditions. I show that existing estimates of the impact of immigration on rents are biased and the source of …


Explore The Relationship Among Lung Cancer Stigma, Social Support, And Psychosocial Distress, Lisa Maggio Jan 2015

Explore The Relationship Among Lung Cancer Stigma, Social Support, And Psychosocial Distress, Lisa Maggio

Theses and Dissertations--Nursing

There is longstanding causal relationship between cigarette smoking and lung cancer. Smoke-free policies and anti-smoking campaigns have been linked to the decline in smoking acceptance and contribute to the unintended consequence of stigmatizing smokers. Lung cancer is viewed as a self-inflicted disease and patients’ feel judged in a manner different from other cancers affecting social interactions between family, friends, and healthcare professionals. Lung cancer stigma contributes to depression, anxiety, poor self-esteem, guilt, shame, blame, threatens a person’s social identity, and limits social support that deeply affects patients and their support persons.

This dissertation contains a review of the literature related …


Introduction, James M. Donovan Jan 2015

Introduction, James M. Donovan

Law Faculty Books and Chapters

The Chosen People, John Allegro’s attempt to uncover the historical sources for the world’s enduring anti-Semitism, bears the marks of his wish to appeal to two disparate readerships. Allegro’s fluent command of the relevant primary literature is more than sufficient reason for his arguments to be taken seriously. He knows whereof he speaks. He spins the details, however, into a story more akin to a gripping potboiler of palace intrigue and political machination than to a dry recitation of long-forgotten events. Relying upon in-text citations, Allegro was scolded by reviewers for eschewing the fully footnoted scholarly apparatus usually found …


Perceptual Dialectology Of New England: Views From Maine And The Web, Benjamin Graham Jones Jan 2015

Perceptual Dialectology Of New England: Views From Maine And The Web, Benjamin Graham Jones

Theses and Dissertations--Linguistics

Research into the dialects of the New England states (Connecticut, New Hampshire, Maine, Massachusetts, Rhode Island, and Vermont) has traditionally split the region into distinct geographic regions based upon variations in production, primarily along an East-West border. Generally, such regions have been considered relatively stable in terms of their variation (Labov, Ash and Boberg 2006); however, recent work in the area has found that the traditional dialect boundaries have begun to shift (c.f. Stanford, Leddy-Cecere and Baclawski 2012). Such research has focused on very specific regional changes in production, ignoring the perceptual salience of the features observed to be in …


Exploring The Process, Models, And Outcomes Of Hospital-Public Health Partnerships, Danielle M. Varda, Jessica H. Retrum, Carrie Chapman Dec 2014

Exploring The Process, Models, And Outcomes Of Hospital-Public Health Partnerships, Danielle M. Varda, Jessica H. Retrum, Carrie Chapman

Frontiers in Public Health Services and Systems Research

Health care reform has resulted in changes throughout the health system, including the Affordable Care Act (ACA) requirement that hospitals conduct community health needs assessments, taking into greater consideration the public health of their respective communities. This has led to growing strategies to develop partnerships between hospitals and public health (PH) as a way to meet these needs1. Meantime, there is a need for data on Hospital-PH partnerships, due to the growing emphasis that these types of partnerships get implemented in practice. In this paper we analyze a secondary data set to explore how hospitals and public health …


A Case Study Of Cross-Jurisdiction Resource Sharing: The Merger Of Two Tuberculosis Clinics In East Tennessee., Anne Kershenbaum, Margaret A. Knight, Martha L. Buchanan, Janet Ridley, Paul C. Erwin Dec 2014

A Case Study Of Cross-Jurisdiction Resource Sharing: The Merger Of Two Tuberculosis Clinics In East Tennessee., Anne Kershenbaum, Margaret A. Knight, Martha L. Buchanan, Janet Ridley, Paul C. Erwin

Frontiers in Public Health Services and Systems Research

Cross-jurisdiction resource sharing is considered a possible means to improve efficiency and effectiveness of public health service delivery. A merger of the Tuberculosis (TB) clinics of a rural and a metropolitan jurisdiction in East Tennessee provided an opportunity to study service provision changes in real time. A mixed methods approach was used, including quantitative data on latent TB treatment outcomes and qualitative data from staff interviews, as well as documentation of changes in staffing time in TB services. Results showed a mix of efficiency changes, indicating probable increased pressure on key service providers after the merger, in addition to expected …


Health Communication As A Public Health Training And Workforce Development Issue, Nancy L. Winterbauer, Ann P. Rafferty, Katherine A. Jones, Mary Tucker-Mclaughlin, Colleen Bridger Dec 2014

Health Communication As A Public Health Training And Workforce Development Issue, Nancy L. Winterbauer, Ann P. Rafferty, Katherine A. Jones, Mary Tucker-Mclaughlin, Colleen Bridger

Frontiers in Public Health Services and Systems Research

Effective communication is one of the core competencies for public health professionals and is required for local health department (LHD) accreditation. Public health communication specialists play a critical role as conduits of health information, particularly with regard to managing relationships with media and the message that is ultimately represented by news outlets. However, capacity for engagement with traditional media in community health improvement at the local level has not been well-described. As part of a larger study examining the use and impact of the County Health Rankings in North Carolina, LHD media staffing and interaction with traditional media were examined …


What “Community Building” Activities Are Nonprofit Hospitals Reporting As Community Benefit?, Erik Bakken, David Kindig, Jo Ivey Boufford Dec 2014

What “Community Building” Activities Are Nonprofit Hospitals Reporting As Community Benefit?, Erik Bakken, David Kindig, Jo Ivey Boufford

Frontiers in Public Health Services and Systems Research

In 2008, the Internal Revenue Service (IRS) revised and standardized the reporting policy for community benefit expenses for nonprofit hospitals. These expenses are required for tax exemption. At that time, the IRS designated some categories of activities as non-eligible as a community benefit, but still mandated their reporting on hospitals’ Form 990, the annual tax filing for nonprofit organizations. One such category was community building, which encompasses a broad range of nonmedical determinants of health and an important potential source of population health revenue. This is the first study to analyze community-building dollars at any level, examining New York State’s …


Sugihara Causality Analysis Of Scalp Eeg For Detection Of Early Alzheimer's Disease, Joseph C. Mcbride, Xiaopeng Zhao, Nancy B. Munro, Greg A. Jicha, Frederick A. Schmitt, Richard J. Kryscio, Charles D. Smith, Yang Jiang Dec 2014

Sugihara Causality Analysis Of Scalp Eeg For Detection Of Early Alzheimer's Disease, Joseph C. Mcbride, Xiaopeng Zhao, Nancy B. Munro, Greg A. Jicha, Frederick A. Schmitt, Richard J. Kryscio, Charles D. Smith, Yang Jiang

Sanders-Brown Center on Aging Faculty Publications

Recently, Sugihara proposed an innovative causality concept, which, in contrast to statistical predictability in Granger sense, characterizes underlying deterministic causation of the system. This work exploits Sugihara causality analysis to develop novel EEG biomarkers for discriminating normal aging from mild cognitive impairment (MCI) and early Alzheimer's disease (AD). The hypothesis of this work is that scalp EEG based causality measurements have different distributions for different cognitive groups and hence the causality measurements can be used to distinguish between NC, MCI, and AD participants. The current results are based on 30-channel resting EEG records from 48 age-matched participants (mean age 75.7 …


Meeting The Challenge Of Focused Collection Development At A Federal Regional Depository, Sandra Mcaninch, Heath Martin Dec 2014

Meeting The Challenge Of Focused Collection Development At A Federal Regional Depository, Sandra Mcaninch, Heath Martin

Library Presentations

The University of Kentucky (UK) is participating as a Center of Excellence (COE) for the Works Progress Administration (WPA) and the Appalachian Regional Commission (ARC) in the Association of Southeastern Research Libraries‘ (ASERL) Collaborative Federal Depository Program (CFDP). This collaborative effort is designed to distribute collection development for all Federal agencies across the entire Southeast.

We will describe how all depositories are working together to ensure that there are at least two complete collections for each federal agency somewhere in the Southeast, and how UK has focused its depository collection development efforts on non-COE agencies.


The Economics Of Implementing Population Health Strategies: Progress In Public Health Services & Systems Research, Glen P. Mays Dec 2014

The Economics Of Implementing Population Health Strategies: Progress In Public Health Services & Systems Research, Glen P. Mays

Health Management and Policy Presentations

Successful strategies to scale up and spread complex community-level interventions require an understanding of the resources required for implementation, how best to distribute them among supporting institutions, and how resource consumption and distribution varies across settings. This session reviews methods and early findings from the RWJF’s Public Health Delivery and Cost Studies (DACS) Initiative, which includes 12 inter-related studies examining the causes and consequences of variation in the costs of delivering complex community-level prevention strategies across more than 300 community settings in 12 states. Findings from these studies highlight the value of studying the economics of implementation, the measurement and …


Vawa @ 20: Building The Knowledge Base: Research Funding Through Vawa, Claire M. Renzetti, Rebecca M. Campbell, Allison Adair Dec 2014

Vawa @ 20: Building The Knowledge Base: Research Funding Through Vawa, Claire M. Renzetti, Rebecca M. Campbell, Allison Adair

Sociology Faculty Publications

No abstract provided.


Opportunities And Future Directions For The National Health Security Preparedness Index™, Glen P. Mays Dec 2014

Opportunities And Future Directions For The National Health Security Preparedness Index™, Glen P. Mays

Health Management and Policy Presentations

This presentation examines options and opportunities for future development of the National Health Security Preparedness Index, created through a partnership of national public health and health care organizations led by the U.S. Centers for Disease Control and Prevention (CDC) and the Association of State and Territorial Health Officials (ASTHO).


Testing A Risky Sex Behavior Intervention Pilot Website For Adolescents, Randall Starling, Don Helme, Jessica A. Nodulman, Angela D. Bryan, David B. Buller, Robert Lewis Donohew, W. Gill Woodall Dec 2014

Testing A Risky Sex Behavior Intervention Pilot Website For Adolescents, Randall Starling, Don Helme, Jessica A. Nodulman, Angela D. Bryan, David B. Buller, Robert Lewis Donohew, W. Gill Woodall

Communication Faculty Publications

BACKGROUND AND PURPOSE: Each year, teenagers account for about one-fifth of all unintended pregnancies in the United States. As such, delivering sexual risk reduction educational materials to teens in a timely fashion is of critical importance. Web-based delivery of these materials shows promise for reaching and persuading teens away from risky sexual and substance abuse behaviors. The purpose of this study was to pilot test a web-based program aimed at reducing risky sexual behavior and related outcomes among adolescents in a high school setting.

METHODS: A beta-test of the website was conducted in three public schools in New Mexico, USA …


Encryption And Incrimination: The Evolving States Of Encrypted Drives, Shannon M. Oltmann Dec 2014

Encryption And Incrimination: The Evolving States Of Encrypted Drives, Shannon M. Oltmann

Information Science Faculty Publications

Individuals use encryption to safeguard many valid and legal applications but also to hide illegal activity. Several legal cases have drawn the limits of self-incrimination under the Fifth Amendment regarding providing passwords to access illegal information content,such as child pornography. The cases illustrate that certain knowledge of evidence amounts to a compelling need for access and that a subpoena for hard drive contents is more likely to succeed than requiring a witness to provide a password. Since known documents are not legally protected and biometric data can be compelled as evidence, there is no reason that known digital documents, biometric …


The Dynamics Of Medicaid & Public Health Spending: Implications For Aca Implementation, Glen P. Mays Nov 2014

The Dynamics Of Medicaid & Public Health Spending: Implications For Aca Implementation, Glen P. Mays

Health Management and Policy Presentations

We estimate the dynamics and interactions of governmental spending on Medicaid and other public health services in all 50 states over a 15 year period. Using a quasi-experimental design with instrumental variables estimation, we find evidence that increased Medicaid spending leads to reduced governmental spending on other public health services, consistent with a crowd-out effect. Over 10 years, such crowd-out has the potential to diminish the health status improvements generated through health insurance coverage expansions.


Medicaid Expansions & Public Health Spending: Cross-Subsidies, Complementarities, And Crowd-Out, Glen P. Mays Nov 2014

Medicaid Expansions & Public Health Spending: Cross-Subsidies, Complementarities, And Crowd-Out, Glen P. Mays

Health Management and Policy Presentations

In this paper we estimate the causal impact of state Medicaid enrollment expansions and expenditures on state and local resources allocated to other public health programs and services. Using a quasi-experimental design with instrumental variables estimation, we find evidence that increased Medicaid spending leads to reduced governmental spending on other public health services, consistent with a crowd-out effect. Over 10 years, such crowd-out has the potential to diminish the health status improvements generated through health insurance coverage expansions.


Cost Estimates Of Foundational Public Health Services: Results From Piloting An Expert Consensus Methodology, C. B. Mamaril, Glen P. Mays Nov 2014

Cost Estimates Of Foundational Public Health Services: Results From Piloting An Expert Consensus Methodology, C. B. Mamaril, Glen P. Mays

Health Management and Policy Presentations

We review preliminary estimates from pilot testing a cost estimation methodology developed to identify the resources required to implement a set of Foundational Public Health Services as recommended by the Institute of Medicine and defined by the Public Health Leadership Forum.


Geographic Variation In The Delivery Of High-Value Public Health Services: Exploring Causes & Consequences, Glen P. Mays Nov 2014

Geographic Variation In The Delivery Of High-Value Public Health Services: Exploring Causes & Consequences, Glen P. Mays

Health Management and Policy Presentations

OBJECTIVES: A growing body of evidence indicates that the delivery of public health activities varies widely across states and communities, creating missed opportunities for prevention as well as inequities in health protection. Measures of quality in public health are needed to guide public health improvement initiatives and to support research on the comparative effectiveness of alternative public health strategies. The Multi-network Practices and Outcomes Variation Examination Study (MPROVE), uses the infrastructure of six Public Health Practice-Based Research Networks (PBRNs) across the U.S. to develop and validate a “starter set” of measures and to analyze geographic variation delivery across diverse public …


Aca Implementation In Kentucky: Experiences Of An Expansion State, Glen P. Mays Nov 2014

Aca Implementation In Kentucky: Experiences Of An Expansion State, Glen P. Mays

Health Management and Policy Presentations

Kentucky's implementation of the Affordable Care Act has included early successes with insurance coverage expansion through Medicaid and a state-operated health insurance exchange. Signals of improvements in health care accessibility and delivery of preventive services are evident in the first year after coverage expansions. Challenges associated with political opposition, delivery system transformation, and public health financing remain on the state's policy agenda.


Engaging Communities To Identify And Address Environmental Health Literacy Gaps, Anna G. Hoover Nov 2014

Engaging Communities To Identify And Address Environmental Health Literacy Gaps, Anna G. Hoover

Anna G. Hoover

Frequently, decisions about the informational components and delivery mechanisms required to promote effective environmental health literacy are made by such technical experts as toxicologists, chemists, and communication scientists. However, because sensemaking processes are both retrospective and collective, context must be a central component for understanding the particular information needs of communities and stakeholder groups. Individual assessments of and tolerance for environmental health risks are rooted in past and present experiences that are understood, refined, and reinforced through dialogue with others who have shared similar experiences. Thus, the promotion of environmental health literacy requires formative engagement with communities and stakeholders to …


Cost Estimates Of Foundational Public Health Services: Results From Piloting The Expert Consensus Methodology In Kentucky, C. B. Mamaril, Glen P. Mays Nov 2014

Cost Estimates Of Foundational Public Health Services: Results From Piloting The Expert Consensus Methodology In Kentucky, C. B. Mamaril, Glen P. Mays

Health Management and Policy Presentations

We developed a methodology for estimating the resources required to deliver a set of foundational public health capabilities as recommended in the 2012 Institute of Medicine report on public health financing. The capabilities are based on IOM recommendations and defined by a national expert panel convened as part of the Public Health Leadership Forum. This paper presents preliminary estimates from a pilot test of the cost estimation methodology in Kentucky, and outlines plans for the national estimation strategy.


Exploring The Use Patterns Of A Mobile Health Application For Alcohol Addiction Before The Initial Lapse After Detoxification, Ming-Yuan Chih Nov 2014

Exploring The Use Patterns Of A Mobile Health Application For Alcohol Addiction Before The Initial Lapse After Detoxification, Ming-Yuan Chih

Health and Clinical Sciences Faculty Publications

How patients used Addiction-Comprehensive Health Enhancement Support System (A-CHESS), a mobile health intervention, while quitting drinking is worthy exploring. This study is to explore A-CHESS use patterns prior to the initial lapse reported after discharge from inpatient detoxification programs. 142 patients with alcohol addiction from two treatment agencies in the U.S. were included. A comprehensive set of A-CHESS use measures were developed based on a three-level system use framework and three A-CHESS service categories. In latent profile analyses, three A-CHESS system use patterns-inactive, passive, and active users-were found. Compared to the passive users (with the highest chance of the initial …


Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers Ii: Sigma-2/Pgrmc1 Receptors Mediate Abeta 42 Oligomer Binding And Synaptotoxicity, Nicholas J. Izzo, Jinbin Xu, Chenbo Zeng, Molly J. Kirk, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Gary Look, Gilbert Rishton, Hank Safferstein, Carlos Cruchaga, Alison Goate, Michael A. Cahill, Ottavio Arancio, Robert H. Mach, Rolf Craven, Elizabeth Head, Harry Levine Iii, Tara L. Spires-Jones, Susan M. Catalano Nov 2014

Alzheimer's Therapeutics Targeting Amyloid Beta 1–42 Oligomers Ii: Sigma-2/Pgrmc1 Receptors Mediate Abeta 42 Oligomer Binding And Synaptotoxicity, Nicholas J. Izzo, Jinbin Xu, Chenbo Zeng, Molly J. Kirk, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Gary Look, Gilbert Rishton, Hank Safferstein, Carlos Cruchaga, Alison Goate, Michael A. Cahill, Ottavio Arancio, Robert H. Mach, Rolf Craven, Elizabeth Head, Harry Levine Iii, Tara L. Spires-Jones, Susan M. Catalano

Sanders-Brown Center on Aging Faculty Publications

Amyloid beta (Abeta) 1-42 oligomers accumulate in brains of patients with Mild Cognitive Impairment (MCI) and disrupt synaptic plasticity processes that underlie memory formation. Synaptic binding of Abeta oligomers to several putative receptor proteins is reported to inhibit long-term potentiation, affect membrane trafficking and induce reversible spine loss in neurons, leading to impaired cognitive performance and ultimately to anterograde amnesia in the early stages of Alzheimer's disease (AD). We have identified a receptor not previously associated with AD that mediates the binding of Abeta oligomers to neurons, and describe novel therapeutic antagonists of this receptor capable of blocking Abeta toxic …


Alzheimer's Therapeutics Targeting Amyloid Beta 1-42 Oligomers I: Abeta 42 Oligomer Binding To Specific Neuronal Receptors Is Displaced By Drug Candidates That Improve Cognitive Deficits, Nicholas J. Izzo, Agnes Staniszewski, Lillian To, Mauro Fa, Andrew F. Teich, Faisal Saeed, Harrison Wostein, Thomas Walko Iii, Anisha Vaswani, Meghan Wardius, Zanobia Syed, Jessica Ravenscroft, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Patricia Finn, Gary Look, Gilbert Rishton, Hank Safferstein, Miles Miller, Conrad Johanson, Edward Stopa, Manfred Windisch, Birgit Hutter-Paier, Mehrdad Shamloo, Ottavio Arancio, Harry Levine Iii, Susan M. Catalano Nov 2014

Alzheimer's Therapeutics Targeting Amyloid Beta 1-42 Oligomers I: Abeta 42 Oligomer Binding To Specific Neuronal Receptors Is Displaced By Drug Candidates That Improve Cognitive Deficits, Nicholas J. Izzo, Agnes Staniszewski, Lillian To, Mauro Fa, Andrew F. Teich, Faisal Saeed, Harrison Wostein, Thomas Walko Iii, Anisha Vaswani, Meghan Wardius, Zanobia Syed, Jessica Ravenscroft, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Patricia Finn, Gary Look, Gilbert Rishton, Hank Safferstein, Miles Miller, Conrad Johanson, Edward Stopa, Manfred Windisch, Birgit Hutter-Paier, Mehrdad Shamloo, Ottavio Arancio, Harry Levine Iii, Susan M. Catalano

Sanders-Brown Center on Aging Faculty Publications

Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic beta amyloid (Abeta) 1-42 oligomers is proposed to underlie cognitive decline in Alzheimer's disease (AD). Alterations in membrane trafficking induced by Abeta oligomers mediates reduction in neuronal surface receptor expression that is the basis for inhibition of electrophysiological measures of synaptic plasticity and thus learning and memory. We have utilized phenotypic screens in mature, in vitro cultures of rat brain cells to identify small molecules which block or prevent the binding and effects of Abeta oligomers. Synthetic Abeta oligomers bind saturably to a single site on neuronal synapses and induce …


Optimizing Public Health Systems For Population Health Improvement: Institutions, Economics, And Metrics, Glen P. Mays Nov 2014

Optimizing Public Health Systems For Population Health Improvement: Institutions, Economics, And Metrics, Glen P. Mays

Health Management and Policy Presentations

This lecture reviews the evidence concerning the institutional and economic characteristics of public health delivery systems and their impact on population health. Emerging findings from these studies suggest promising pathways for transforming the U.S. public health system in ways that strengthen its effectiveness, efficiency and equity in producing health. .