Open Access. Powered by Scholars. Published by Universities.®

Social and Behavioral Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2012

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 17161 - 17190 of 23316

Full-Text Articles in Social and Behavioral Sciences

Capturing Business Intelligence Required For Targeted Marketing, Demonstrating Value, And Driving Process Improvement, Brian Cox, Margie Jantti Jan 2012

Capturing Business Intelligence Required For Targeted Marketing, Demonstrating Value, And Driving Process Improvement, Brian Cox, Margie Jantti

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

The University of Wollongong (UOW) has undertaken an innovative and collaborative research project to demonstrate the value that can be provided by academic libraries. The tool developed, the “Library Cube”, is a data warehouse linking student borrowing and use of electronic resources to students’ academic grades and demographic information. The project is different to other institutions’ efforts to link usage to student outcomes, in that the Library Cube is not a one-off research project, but is now an ongoing part of UOW’s systems and performance reporting and represents a fundamental shift in evaluating the student experience through the integration of …


Patterns Of Paid Work Among Higher Education Students: Implications For The Bradley Reforms, Joanne Dearlove, James Grice Thomas Marland Jan 2012

Patterns Of Paid Work Among Higher Education Students: Implications For The Bradley Reforms, Joanne Dearlove, James Grice Thomas Marland

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

No abstract provided.


Controlling Shareholders Expropriation And Firms Leverage Decision: Evidence From Chinese Non-Tradable Share Reform, Qigui Liu, Gary Tian Jan 2012

Controlling Shareholders Expropriation And Firms Leverage Decision: Evidence From Chinese Non-Tradable Share Reform, Qigui Liu, Gary Tian

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

This paper examines the effect of excess control rights on the leverage decisions made by Chinese non-SOEs before and after the Non-tradable share reform (NTS reform). We find that firms with excess control rights have more excess leverage and their controlling shareholders use the resources for tunneling rather than investing in positive NPV projects. We also find that excess leverage in firms with excess control rights decreases and the market reaction to announcements of related party transactions are more positive after NTS reform. This confirms that tunneling by the controlling shareholders actually reduced. We argue that in emerging markets where …


Leadership Competencies: A Reference Point For Development And Evaluation, Margie Jantti, Nick Greenhalgh Jan 2012

Leadership Competencies: A Reference Point For Development And Evaluation, Margie Jantti, Nick Greenhalgh

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

Purpose – The purpose of this paper is to establish a transparent, integrated approach to leadership competency development and succession management to respond to drivers associated with an ageing workforce, leadership drain and the enticement of people into leadership roles. Design/methodology/approach – A consultant was engaged to facilitate a review of the UOW Library’s leadership situation. Key to this process and subsequent activities was the use of the Lominger Leadership competencies; measurable characteristics related to success in the workplace to establish the desired leadership profile. Career interviews, professional coaching and targeted assignments were integral to the development of needed competencies. …


Book Review - Developing College Skills In Students With Autism And Asperger's Syndrome, Kimberley Mcmahon-Coleman Jan 2012

Book Review - Developing College Skills In Students With Autism And Asperger's Syndrome, Kimberley Mcmahon-Coleman

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

The support and success of students with disabilities is a key aspect of the social inclusion agenda. This cohort has been identified by the Bradley Report as one of the under-represented student groups requiring attention. In recent years, Australian universities have reflected a marked increase in students with registered disabilities. Many of these are "invisible" disabilities such as learning disorders, mental health disorders, or students with Autism Spectrum Disorder.


Editorial: Social Inclusion--Are We There Yet?, Kimberley Mcmahon-Coleman, Alisa Percy, Bronwyn James Jan 2012

Editorial: Social Inclusion--Are We There Yet?, Kimberley Mcmahon-Coleman, Alisa Percy, Bronwyn James

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

This special edition of the Journal of Academic Language and Learning arose out of a Forum titled Critical Discussions about Social Inclusion held at the University of Wollongong, Australia in June 2011. It was organised by academic language and learning educators from five different universities: Ingrid Wijeyewardene from the University of New England, Helen Drury from the University of Sydney, Caroline San Miguel from the University of Technology Sydney, Stephen Milnes from the Australian National University, and ourselves from the University of Wollongong. Initially funded by a grant from the Association for Academic Language and Learning, this funding was later …


Ferdinand Hochstetter In Australia, 1858-1859, Michael K. Organ Jan 2012

Ferdinand Hochstetter In Australia, 1858-1859, Michael K. Organ

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

The visit to Australia in 1858 of the Austrian Imperial Frigate Novara was part of a flag-waving exercise by the Austrian Habsburg monarchy, though it acquired added significance due to the inclusion on board of a scientific contingent comprising Ferdinand Hochstetter (geologist); Georg Frauenfeld and Johann Zelebor (zoologists); Eduard Schwarz and Anton Jelinek (botanists); Karl Scherzer (historiographer, ethnographer and economist); and Joseph Selleny (artist). Members of the crew, including Commodore Bernhard von WullerstorfUrbair and Lt. Robert Muller, were also expert in the fields of meteorology, hydrography, oceanography, geophysics and linguistics. The records of these scientists and their various collections would …


Teaching Academic Writing At The University Of Wollongong, Emily Rose Purser Jan 2012

Teaching Academic Writing At The University Of Wollongong, Emily Rose Purser

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

Initiatives for the development of literacy at the University of Wollongong are growing within an Australian national commitment to increase overall tertiary enrollment, provide access to students from less-advantaged groups, and enroll more international students. While this essay describes successful programs within the Academic Services Division at Wollongong built to support student literacy, especially academic writing, it primarily emphasizes the work of a problemsolving task force on English language proficiency aimed at building consensus for a collaborative, cross-disciplinary paradigm of literacy growth that moves away from the traditional idea of separable services. The essay profiles a new initiative in the …


The (New) Accident Of Art, Su Ballard Jan 2012

The (New) Accident Of Art, Su Ballard

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

Accidental encounters in the art gallery occupy a critical space that moves visitors beyond established behaviours and expectations. Accidents are crucial to everyday encounters with art objects and tend to occur in the interval between images. The emergence of the 'New Aesthetic' in March 2012 contributed to a more generalised interest in spotting and documenting moments where the digital intercedes in the everyday. The New Aesthetic suggests that it is possible to see accidental spaces of machinic vision. But what happens when the viewer is also not human? Does the robot machine employed by GoogleArtProject to patrol the major galleries …


Metropolis: Rotwang's Robot, Revolution And Redemption, Michael K. Organ Jan 2012

Metropolis: Rotwang's Robot, Revolution And Redemption, Michael K. Organ

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

The objects in the exhibition Metropolis: Rotwang's Robot, Revolution and Redemption started out as marketing material for the landmark 1927 film Metropolis, by German director Fritz Lang. In the intervening years they have evolved from commercial products into memorabilia and collectables - the works in this exhibition all come from the private collection of former Greens MP Michael Organ.


Alone Yet Not Alone: Networks And Regional Facilitation In Leading A University Campus, Robbie Collins Jan 2012

Alone Yet Not Alone: Networks And Regional Facilitation In Leading A University Campus, Robbie Collins

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

Abstract presented at the London Women's Leadership Symposium, The Oxford and Cambridge Club, London, 8-9 December 2012


Discovering The Impact Of Library Use And Student Performance, Brian L. Cox, Margie H. Jantti Jan 2012

Discovering The Impact Of Library Use And Student Performance, Brian L. Cox, Margie H. Jantti

Senior Deputy Vice-Chancellor and Deputy Vice-Chancellor (Education) - Papers

Key Takeaways • Without a valid, reliable way to collect data from various library and enterprise systems, it's difficult to quantitatively assert how a library adds value. • University of Wollongong Library developed the Library Cube, a tailored database and reporting function that joins library usage data with student data, including demographic and academic performance information. • Analysis of the resulting data reveals a strong correlation between students' grades and use of information resources the library provides.


Inorganic Arsenic And Iron(Ii) Distributions In Sediment Porewaters Investigated By A Combined Dgt - Colourimetric Det Technique, William Bennett, Peter R. Teasdale, David T. Welsh, Jarad Panther, Ryan R. Stewart, Helen L. Price, Dianne F. Jolley Jan 2012

Inorganic Arsenic And Iron(Ii) Distributions In Sediment Porewaters Investigated By A Combined Dgt - Colourimetric Det Technique, William Bennett, Peter R. Teasdale, David T. Welsh, Jarad Panther, Ryan R. Stewart, Helen L. Price, Dianne F. Jolley

Faculty of Science - Papers (Archive)

No abstract provided.


Ch4, Co, And H2o Spectroscopy For The Sentinel-5 Precursor Mission: An Assessment With The Total Carbon Column Observing Network Measurements, A Galli, A Butz, R A. Scheepmaker, O Hasekamp, J Landgraf, P Tol, D Wunch, N M. Deutscher, G C. Toon, P O. Wennberg, D W. T Griffith, I Aben Jan 2012

Ch4, Co, And H2o Spectroscopy For The Sentinel-5 Precursor Mission: An Assessment With The Total Carbon Column Observing Network Measurements, A Galli, A Butz, R A. Scheepmaker, O Hasekamp, J Landgraf, P Tol, D Wunch, N M. Deutscher, G C. Toon, P O. Wennberg, D W. T Griffith, I Aben

Faculty of Science - Papers (Archive)

The TROPOspheric Monitoring Instrument (TROPOMI) will be part of ESA’s Sentinel-5 Precursor (S5P) satellite platform scheduled for launch in 2015. TROPOMI will monitor methane and carbon monoxide concentrations in the Earth’s atmosphere by measuring spectra of back-scattered sunlight in the short-wave infrared (SWIR).


Does Cytotoxicity Of Metallointercalators Correlate With Cellular Uptake Or Dna Affinity?, Kimberley J. Davis, Judith A. Carrall, Barry Lai, Janice R. Aldrich-Wright, Stephen F. Ralph, Carolyn T. Dillon Jan 2012

Does Cytotoxicity Of Metallointercalators Correlate With Cellular Uptake Or Dna Affinity?, Kimberley J. Davis, Judith A. Carrall, Barry Lai, Janice R. Aldrich-Wright, Stephen F. Ralph, Carolyn T. Dillon

Faculty of Science - Papers (Archive)

The cytotoxicity of the metallointercalators, [Pt(5,6-dimethyl-1,10-phenanthroline)(trans-1R,2Rdiaminocyclohexane)] 2+ ([56MERR]) and [Pt(5,6-dimethyl-1,10-phenanthroline)(trans-1S,2Sdiaminocyclohexane)] 2+ ([56MESS]), towards A549 human lung cancer cells was examined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The IC50 value obtained following exposure of A549 cells to [56MESS] for 4 h was approximately three times smaller than that obtained when [56MERR] was administered under the same conditions, indicating that the former complex displayed greater cytotoxicity. Both IC50 values were greater than that obtained after exposure of A549 cells to cisplatin, demonstrating that the latter compound was the most cytotoxic of the three examined. Microprobe synchrotron radiation X-ray fluorescence (SR-XRF) analyses of …


A Simple Post-Hoc Method To Add Spatial Context To Predictive Species Distribution Models, Michael B. Ashcroft, Kristine O. French, Laurie A. Chisholm Jan 2012

A Simple Post-Hoc Method To Add Spatial Context To Predictive Species Distribution Models, Michael B. Ashcroft, Kristine O. French, Laurie A. Chisholm

Faculty of Science - Papers (Archive)

Methods to incorporate spatial context into species distribution models (SDMs) are underutilised, with predictions usually based only on environmental space and ignoring geographic space. The goals of this study were to demonstrate a relatively simple post-hoc method to include spatial context in SDMs and to quantify the improvement over purely niche-based models. The method involved producing a standard niche-based model using established techniques, such as Maxent, and then calculating the neighbourhood average of the model output in geographic space. In effect, we tested whether the spatially averaged model output was better at predicting species distributions than the raw model output. …


Activity And Molecular Dynamics Relationship Within The Family Of Human Cholinesterase, Judith Peters, Marie Trovaslet, Marcus Trapp, Florian Nachon, Flynn Hill, Etienne Royer, Frank Gabel, Lambert Van Eijck, Patrick Masson, Moeava Tehei Jan 2012

Activity And Molecular Dynamics Relationship Within The Family Of Human Cholinesterase, Judith Peters, Marie Trovaslet, Marcus Trapp, Florian Nachon, Flynn Hill, Etienne Royer, Frank Gabel, Lambert Van Eijck, Patrick Masson, Moeava Tehei

Faculty of Science - Papers (Archive)

The temperature dependence of the dynamics of recombinant human acetylcholinesterase (hAChE) and plasma human butyrylcholinesterase (hBChE) is examined using elastic incoherent neutron scattering. These two enzymes belong to the same family and present 50% amino acid sequence identity. However, significantly higher flexibility and catalytic activity of hAChE when compared to the ones of hBChE are measured. At the same time, the average height of the potential barrier to the motions is increased in the hBChE, e.g. more thermal energy is needed to cross it in the latter case, which might be the origin of the increase in activation energy and …


Atmospheric Greenhouse Gases Retrieved From Sciamachy: Comparison To Ground-Based Fts Measurements And Model Results, O Schneising, P Bergamaschi, H Bovensmann, M Buchwitz, J P. Burrows, N M. Deutscher, D W. T Griffith, J Heymann, R Macatangay, J Messerschmidt, J Notholt, M Rettinger, M Reuter, R Sussmann, Voltaire A. Velazco, T Warneke, P O. Wennberg, D Wunch Jan 2012

Atmospheric Greenhouse Gases Retrieved From Sciamachy: Comparison To Ground-Based Fts Measurements And Model Results, O Schneising, P Bergamaschi, H Bovensmann, M Buchwitz, J P. Burrows, N M. Deutscher, D W. T Griffith, J Heymann, R Macatangay, J Messerschmidt, J Notholt, M Rettinger, M Reuter, R Sussmann, Voltaire A. Velazco, T Warneke, P O. Wennberg, D Wunch

Faculty of Science - Papers (Archive)

SCIAMACHY onboard ENVISAT (launched in 2002) enables the retrieval of global long-term columnaveraged dry air mole fractions of the two most important anthropogenic greenhouse gases carbon dioxide and methane (denoted XCO2 and XCH4). In order to assess the quality of the greenhouse gas data obtained with the recently introduced v2 of the scientific retrieval algorithm WFM-DOAS, we present validations with ground-based Fourier Transform Spectrometer (FTS) measurements and comparisons with model results at eight Total Carbon Column Observing Network (TCCON) sites providing realistic error estimates of the satellite data. Such validation is a prerequisite to assess the suitability …


Emulsion-Coaxial Electrospinning: Designing Novel Architectures For Sustained Release Of Highly Soluble Low Molecular Weight Drugs, Lucie Viry, Simon E. Moulton, Tony Romeo, Courtney Suhr, Damia Mawad, Mark Cook, Gordon G. Wallace Jan 2012

Emulsion-Coaxial Electrospinning: Designing Novel Architectures For Sustained Release Of Highly Soluble Low Molecular Weight Drugs, Lucie Viry, Simon E. Moulton, Tony Romeo, Courtney Suhr, Damia Mawad, Mark Cook, Gordon G. Wallace

Faculty of Science - Papers (Archive)

In drug therapy, most therapeutic drugs are of low molecular weight and could freely diffuse in the biological milieu depending on the administration route applied. The main reason for the development of polymeric drug carriers is to obtain desired effects such as sustained therapy, local and controlled release, prolonged activity and reduction of side effects. Alternatively, polymeric carriers can be made bioerodible in order to be eliminated by natural ways after a certain time of therapy. Core-shell fibres from coaxial spinneret or emulsion electrospinning are good candidates for the development of such devices; however difficulties remain especially in controlling the …


Direct Exfoliation Of Graphite With A Porphyrin - Creating Functionalizable Nanographene Hybrids, Jenny Malig, Adam W. I Stephenson, Pawel Wagner, Gordon G. Wallace, David L. Officer, Dirk M. Guldi Jan 2012

Direct Exfoliation Of Graphite With A Porphyrin - Creating Functionalizable Nanographene Hybrids, Jenny Malig, Adam W. I Stephenson, Pawel Wagner, Gordon G. Wallace, David L. Officer, Dirk M. Guldi

Faculty of Science - Papers (Archive)

Exfoliation of graphite was achieved using a free-base porphyrin 1 resulting in an efficient fabrication of single-layer nanographene (NG)-1 hybrid platelets that can be further functionalized with other nanomaterials. The novel nanographene-porphyrin hybrids reveal efficient charge transfer in the excited state.


High-Yield Cell-Free Protein Synthesis For Site-Specific Incorporation Of Unnatural Amino Acids At Two Sites, Kiyoshi Ozawa, Karin V. Loscha, Kekini V. Kuppan, Choy Theng Loh, Nicholas E. Dixon, Gottfried Otting Jan 2012

High-Yield Cell-Free Protein Synthesis For Site-Specific Incorporation Of Unnatural Amino Acids At Two Sites, Kiyoshi Ozawa, Karin V. Loscha, Kekini V. Kuppan, Choy Theng Loh, Nicholas E. Dixon, Gottfried Otting

Faculty of Science - Papers (Archive)

Using aminoacyl-tRNA synthetase/suppressor tRNA pairs derived from Methanocaldococcus jannaschii, an Escherichia coli cell-free protein production system affords proteins with site-specifically incorporated unnatural amino acids (UAAs) in high yields through the use of optimized amber suppressor tRNACUA opt and optimization of reagent concentrations. The efficiency of the cell-free system allows the incorporation of trifluoromethyl-phenylalanine using a polyspecific synthetase evolved previously for p-cyanophenylalanine, and the incorporation of UAAs at two different sites of the same protein without any re-engineering of the E. coli cells used to make the cell-free extract.


Dgt-Induced Copper Flux Predicts Bioaccumulation And Toxicity To Bivalves In Sediments With Varying Properties, Stuart L. Simpson, Heloise Yverneau, Anne Cremazy, Chad V. Jarolimek, Helen Price, Dianne F. Jolley Jan 2012

Dgt-Induced Copper Flux Predicts Bioaccumulation And Toxicity To Bivalves In Sediments With Varying Properties, Stuart L. Simpson, Heloise Yverneau, Anne Cremazy, Chad V. Jarolimek, Helen Price, Dianne F. Jolley

Faculty of Science - Papers (Archive)

Many regulatory frameworks for sediment quality assessment include consideration of contaminant bioavailability. However, the “snap-shots” of metal bioavailability provided by analyses of porewaters or acid-volatile sulfidesimultaneously extractable metal (AVS-SEM) relationships do not always contribute sufficient information. The use of inappropriate or inadequate information for assessing metal bioavailability in sediments may result in incorrect assessment decisions. The technique of diffusive gradients in thin films (DGT) enables the in situ measurement of metal concentrations in waters and fluxes from sediment porewaters. We utilized the DGT technique to interpret the bioavailability of copper to the benthic bivalve Tellina deltoidalis in sediments of varying …


Molecular Characterization Of A 21.4 Kilobase Antibiotic Resistance Plasmid From An Hemolytic Escherichia Coli O108:H-Human Clinical Isolate, Fay E. Dawes, Dieter M. Bulach, Alexander Kuzevski, Karl A. Bettelheim, Carola Venturini, Steven P. Djordjevic, Mark J. Walker Jan 2012

Molecular Characterization Of A 21.4 Kilobase Antibiotic Resistance Plasmid From An Hemolytic Escherichia Coli O108:H-Human Clinical Isolate, Fay E. Dawes, Dieter M. Bulach, Alexander Kuzevski, Karl A. Bettelheim, Carola Venturini, Steven P. Djordjevic, Mark J. Walker

Faculty of Science - Papers (Archive)

This study characterizes the 21.4 kilobase plasmid pECTm80 isolated from Escherichia coli strain 80, an α hemolytic human clinical diarrhoeal isolate (serotype O108:H-). DNA sequence analysis of pECTm80 revealed it belonged to incompatibility group X1, and contained plasmid partition and toxin-antitoxin systems, an R6K-like triple origin (ori) replication system, genes required for replication regulation, insertion sequences IS1R, ISEc37 and a truncated transposase gene (Tn3-like ΔtnpA) of the Tn3 family, and carried a class 2 integron. The class 2 integron of pECTm80 contains an intact cassette array dfrA1-sat2, encoding resistance to trimethoprim and streptothricin, …


Isolation Of Tuberospironine A, A Novel Croomine Derivative From Stemona Tuberosa Lour., Pratiwi Pudjiastuti, Stephen G. Pyne, S Sugiyanto, Wilford Lie Jan 2012

Isolation Of Tuberospironine A, A Novel Croomine Derivative From Stemona Tuberosa Lour., Pratiwi Pudjiastuti, Stephen G. Pyne, S Sugiyanto, Wilford Lie

Faculty of Science - Papers (Archive)

A novel croomine derivative, tuberospironine A (3-epi-tuberospironine) was isolated from the root extracts of Stemona tuberosa Lour. found growing on Seram Island, Moluccas Province, Indonesia. The structure of this novel alkaloid, with unprecedented configuration at C-3 for a croomine derivative, was determined from interpretation of its NMR spectroscopic data.


Activation Of The Damage-Associated Molecular Pattern Receptor P2x7 Induces Interleukin-1b Release From Canine Monocytes, Iman Jalilian, Michelle Peranec, Belinda L. Curtis, Aine Seavers, Mari Spildrejorde, Vanessa Sluyter, Ronald Sluyter Jan 2012

Activation Of The Damage-Associated Molecular Pattern Receptor P2x7 Induces Interleukin-1b Release From Canine Monocytes, Iman Jalilian, Michelle Peranec, Belinda L. Curtis, Aine Seavers, Mari Spildrejorde, Vanessa Sluyter, Ronald Sluyter

Faculty of Science - Papers (Archive)

P2X7, a damage-associated molecular pattern receptor and adenosine 5'-triphosphate (ATP)-gated cation channel, plays an important role in the activation of the NALP3 inflammasome and subsequent release of interleukin (IL)-1β from human monocytes; however its role in monocytes from other species including the dog remains poorly defined. This study investigated the role of P2X7 in canine monocytes, including its role in IL-1β release. A fixed-time flow cytometric assay demonstrated that activation of P2X7 by extracellular ATP induces the uptake of the organic cation, YO-PRO-12+, into peripheral blood monocytes from various dog breeds, a process impaired by the specific P2X7 …


Engaging Creative Communities In An Industrial City Setting, Chris Gibson, Ben Gallan, Andrew Warren Jan 2012

Engaging Creative Communities In An Industrial City Setting, Chris Gibson, Ben Gallan, Andrew Warren

Faculty of Science - Papers (Archive)

Much has been said about how ‘creativity’ might infuse policymaking and planning – especially in the wake of popular bestsellers by Richard Florida and Charles Landry on ‘creative places’ and the ‘creative class’ (the latter a supposed demographic group associated with creative industries such as film, design and music, who are said to be the key to the economic fortunes of cities). Creativity, it is said, can be facilitated in particular urban environments, given the right preconditions such as ‘hip’ inner-city precincts, café culture and walkable dense clusters of design firms and retail and residential spaces. The common argument is …


Molecular Characterization Of Escherichia Coli Strains That Cause Symptomatic And Asymptomatic Urinary Tract Infections, Sam Abraham, Toni A. Chapman, Ren Zhang, James Chin, Amanda N. Mabbett, Makrina Totsika, Mark A. Schembri Jan 2012

Molecular Characterization Of Escherichia Coli Strains That Cause Symptomatic And Asymptomatic Urinary Tract Infections, Sam Abraham, Toni A. Chapman, Ren Zhang, James Chin, Amanda N. Mabbett, Makrina Totsika, Mark A. Schembri

Faculty of Science - Papers (Archive)

The differences between Escherichia coli strains associated with symptomatic and asymptomatic urinary tract infections (UTIs) remain to be properly determined. Here we examined the prevalence of plasmid types and bacteriocins, as well as genetic relatedness, in a defined collection of E. coli strains that cause UTIs. Comparative analysis identified a subgroup of strains with a high number of virulence genes (VGs) and microcins M/H47. We also identified associations between microcin genes, VGs, and specific plasmid types.


Molecular Dynamics Analysis Of Apolipoprotein-D - Lipid Hydroperoxide Interactions: Mechanism For Selective Oxidation Of Met-93, Aaron J. Oakley, Surabhi Bhatia, Heath Ecroyd, Brett Garner Jan 2012

Molecular Dynamics Analysis Of Apolipoprotein-D - Lipid Hydroperoxide Interactions: Mechanism For Selective Oxidation Of Met-93, Aaron J. Oakley, Surabhi Bhatia, Heath Ecroyd, Brett Garner

Faculty of Science - Papers (Archive)

Background: Recent studies suggest reduction of radical-propagating fatty acid hydroperoxides to inert hydroxides by interaction with apolipoprotein-D (apoD) Met93 may represent an antioxidant function for apoD. The nature and structural consequences of this selective interaction are unknown.

Methodology/Principal Findings: Herein we used molecular dynamics (MD) analysis to address these issues. Longtimescale simulations of apoD suggest lipid molecules are bound flexibly, with the molecules free to explore multiple conformations in a binding site at the entrance to the classical lipocalin ligand-binding pocket. Models of 5s- 12s- and 15s hydroperoxyeicosatetraenoic acids were created and the lipids found to wrap around Met93 thus …


Characterization Of Gellan Gum By Capillary Electrophoresis, Danielle L. Taylor, Cameron J. Ferris, Alison R. Maniego, Patrice Castignolles, Marc In Het Panhuis, Marianne Gaborieau Jan 2012

Characterization Of Gellan Gum By Capillary Electrophoresis, Danielle L. Taylor, Cameron J. Ferris, Alison R. Maniego, Patrice Castignolles, Marc In Het Panhuis, Marianne Gaborieau

Faculty of Science - Papers (Archive)

Gellan gums were characterised for the first time using free-solution capillary electrophoresis (CE) or CE under critical conditions (CE-CC). CE-CC is a fast method that separates the polysaccharide. Gellan gums are shown to be heterogeneous in terms of their electrophoretic mobility at 55°C revealing: oligomer peak(s), broad peaks of polymers with a random coil conformation with different degrees of acylation (composition), aggregates, and polymers with double-helix conformation. CE-CC is complementary with the rheological analysis also performed in this work. Sonication of gellan gums is shown to decrease the viscosity of gellan gum mainly by breaking up aggregates. The effect of …


Self-Assembled Gels From Biological And Synthetic Polyelectrolytes, Paul Calvert, Skander Limem, Don Mccallum, Gordon G. Wallace, Marc In Het Panhuis Jan 2012

Self-Assembled Gels From Biological And Synthetic Polyelectrolytes, Paul Calvert, Skander Limem, Don Mccallum, Gordon G. Wallace, Marc In Het Panhuis

Faculty of Science - Papers (Archive)

Inkjet printing of alternate layers of anionic and cationic polyelectrolytes allows organized gels to form with structures similar to those made by layer--by-layer dipping methods but very much faster. Structures of gels formed using slow and fast inkjet printing systems are compared using elemental analysis, swelling and diffusion kinetics as characterization methods. After printing and washing, most sodium or chloride counter-ions are last from the gel, leave only the polymer complex. The swelling properties of the printed and washed gel depend on the deposition rate and on the ratio of the two polymers as originally printed. The synthetic polyelectrolytes reported …