Social and Behavioral Sciences Commons^™

Characterizing Risk & Burden Of Lower Cranial Neuropathy (Lcnp) As Late Effect Among Oropharyngeal Cancer Survivors, Puja Aggarwal

Dissertations & Theses (Open Access)

Background: Lower cranial neuropathy (LCNP) is a rare but potentially disabling late effect of radiotherapy (RT) and other head and neck cancer therapies. Survivors who develop late LCNP may experience profound functional impairment with deficits in swallowing, speech, and voice. The aims of this research were: 1) to quantify the cumulative incidence of late LCNP and identify clinical predictors of late LCNP; 2) to investigate the impact of late LCNP on severity of cancer treatment-related symptoms, general functional impairment (GFI), and single item scores of the most severe symptoms; and 3) to quantify the association of late LCNP with swallowing-related …

Coy Arjate Adrusted Response Adaptive Randomization Designs With Targeted Learning, Hai Zhu

Dissertations & Theses (Open Access)

Since Food and Drug Administration (FDA) issued the very first draft guidance in 2010, adaptive designs have been considered to be one of the most promising approaches to make drug development more efficient and less costly. Two approaches, covariate-adjusted response-adaptive (CARA) randomization and adaptive seamless phase II/III design (ASD) have garnered growing attention recently. However, most of the CARA designs are based on parametric models and suffered from model misspecification. The research of incorporating CARA into ASD is also limited and whether type I error rate can be controlled has not been answered. In this dissertation, a new family of …

Patient-Perceived Patient-Centered Medical Home Characteristics And Healthcare Utilization, Expenditure And Quality, Alissa Ratanatawan

Dissertations & Theses (Open Access)

The patient-centered medical home (PCMH) model is a care delivery model which patient treatment is coordinated through their primary care physician to ensure they receive the necessary care when and where they need it, in a manner they can understand with the aims to improve healthcare quality while keeping healthcare cost growth under control. The objective of this study was to analyze health service utilization, expenditure and quality of civilian noninstitutionalized US adult population in healthcare facilities that have 3 domains of PCMH features, which are comprehensive care, patient-centered care, and accessible care, using patient’s perspective from the 2016 Medical …

Clinical And Demographic Factors Associated With Peg-Asparaginase-Related Toxicities In Patients With Acute Lymphoblastic Leukemia, Priyadarshani Dharia

Dissertations & Theses (Open Access)

Introduction: Polyethylene glycol (PEG)-asparaginase is one of the first-line drugs in pediatric ALL treatment. Although a complete and prolonged treatment with PEGasparaginase has been instrumental in improving the survival of ALL patients, it is associated with four common toxicities: hypersensitivity, hyperbilirubinemia, pancreatitis, and venous thromboembolism (VTE). PEG-asparaginase-related toxicities may require modifications and delays in treatment, which often leads to poor treatment outcomes. Previous studies of PEG-asparaginase-related toxicities have mainly focused on individual toxicities. Further, these studies were conducted in study populations which were predominantly self-reported non-Hispanic whites. Therefore, there is a gap in the knowledge regarding the cumulative burden of …

Moving Beyond The Single Gene: Integrative Gene Set Analysis For Rna-Seq, Andrew Richard Aschenbrenner

Dissertations & Theses (Open Access)

RNA-seq is the next-generation sequencing technology for gene expression and while many tools have been developed to assess differential expression, most focus on gene-level statistics. Gene-level statistics implicitly ignore any dependence among genes. In order to directly incorporate correlation into testing for differential expression, genes are sorted into networks using Ingenuity Pathway Analysis (IPA) and the gene expression of each network is modeled using Generalized Estimating Equations (GEE). Since the gene network data often exhibits correlation structures containing positive and negative values, a new intermediate correlation structure is developed. This structure provides a compromise between an exchangeable (one parameter for …

Nonlinear Functional Models On Causal Inference, Rong Jiao

Dissertations & Theses (Open Access)

Statistical analysis has experienced significant progress on association study, but it remains elusive to understand the etiology and mechanism of complex phenotypes. As a major analytical platform, association analysis may hamper the theoretic development of biomedical science and its application. Thus, many researchers suggest making the transition from association to causation. The mainstream of research in genetics and epigenetics data analysis focuses on statistical association or exploring statistical dependence between variables. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), the signals identified by association analysis can only explain a small proportion of …

Additional Graduate Degrees Associated With Promotion Among Primary Care Clinical Faculty, Michael A. Hansen

Dissertations & Theses (Open Access)

Introduction: Many young and ambitious physicians purposefully seek out meaningful careers in academic medicine, yet there are no evidence-based findings to assist these individuals in how to succeed in advancing their careers in this unique work environment. For early and mid-career faculty, a growing number of trainings and opportunities are available but with little insight as to which choices may have the biggest impact. One common perception is the need for additional advanced training, such as a Master of Public Health. Aims and Method: This study sought to provide evidence-based information about additional training by quantifying the benefit of added …

Quantifying The Financial & Clinical Impact Of Annual Vs. Biennial Mammography Screening, Danmeng Huang

Dissertations & Theses (Open Access)

Current guidelines for screening mammography recommend different start ages and intervals for women with average cancer risk. Longer intervals between mammograms allow more time for a tumor to grow, to become symptomatic and clinically detectable, and more likely to be at advanced stage. Existing literature on the associations between mammography screening frequency and risk of more advanced breast cancer have mixed results. Studies have showed that advanced breast cancer costs more to treat, but real-world cost estimates following different mammography screening frequencies are unavailable. To fill the gaps, this dissertation aimed to quantify the clinical and financial impact following annual …

Nonlinear Functional Models On Causal Inference, Rong Jiao

Dissertations & Theses (Open Access)

Statistical analysis has experienced significant progress on association study, but it remains elusive to understand the etiology and mechanism of complex phenotypes. As a major analytical platform, association analysis may hamper the theoretic development of biomedical science and its application. Thus, many researchers suggest making the transition from association to causation. The mainstream of research in genetics and epigenetics data analysis focuses on statistical association or exploring statistical dependence between variables. Despite significant progress in dissecting the genetic architecture of complex diseases by genome-wide association studies (GWAS), the signals identified by association analysis can only explain a small proportion of …

Understanding The Relatlonships Between Survivorship Care Plans And Survivor Level Outcomes Among Breast And Colorectal Cancer Survivors, Jessica Danielle Austin

Dissertations & Theses (Open Access)

PURPOSE: Cancer survivors have complex journeys following the completion of active treatment. The Institute of Medicine and other high-profile organizations have recommended and mandated the use of a survivorship care plan (SCP) despite mixed evidence supporting the impact of SCPs on key survivor-level outcomes. The purpose of this dissertation was to understand the complex relationship linking the delivery of SCPs and to relevant survivorlevel outcomes. STUDY GROUP: This dissertation focuses on breast and colorectal cancer survivors because they comprise nearly 30% of the entire cancer survivor population in the US and are the two most prevalent cancers in men and …

Communications And Methodologies In Crime Geography: Contemporary Approaches To Disseminating Criminal Incidence And Research, Mitchell Ogden

Electronic Theses and Dissertations

Many tools exist to assist law enforcement agencies in mitigating criminal activity. For centuries, academics used statistics in the study of crime and criminals, and more recently, police departments make use of spatial statistics and geographic information systems in that pursuit. Clustering and hot spot methods of analysis are popular in this application for their relative simplicity of interpretation and ease of process. With recent advancements in geospatial technology, it is easier than ever to publicly share data through visual communication tools like web applications and dashboards. Sharing data and results of analyses boosts transparency and the public image of …

Participatory Modeling Of Tidal Circulation On Maine Mudflats To Improve Water Quality Management Of Shellfish Areas, Gabrielle V. Hillyer

Electronic Theses and Dissertations

Over the past decade, researchers have become increasingly aware of the vital role stakeholder knowledge plays in understanding complex social and environmental problems. Incorporating stakeholder knowledge into understanding complex problems allows for greater awareness and identification of community needs and can help build partnerships to support the development of applied research. In this thesis, I demonstrate the value of stakeholder knowledge and research partnerships by focusing on the soft-shell clamming industry in Maine and how a complex collaboration between clammers, municipal officials, representatives from state agencies, researchers, and other partners relied on and build adaptive capacity to address complex water …

A Consumer Neuroscience Study Of Conscious And Subconscious Destination Preference, Thomas Zoëga Ramsøy, Noela Michael, Ian Michael

All Works

© 2019, The Author(s). In studying consumer behaviors, the inclusion of neuroscience tools and methods is improving our understanding of preference formation and choice. But such responses are mostly related to the consumption of goods and services that meet an immediate need. Tourism represents a consumer behavior that is related to a more complex decision-making process, involving a stronger relationship with a future self, and choices typically being of a higher level of involvement and of a transformational type. The aim of this study was to test whether direct emotional and cognitive responses to travel destination would be indicative of …

Memorializing The Right To Free Speech: Hess V. Indiana And The Iu Bicentennial, Ashley A. Ahlbrand

Articles by Maurer Faculty

No abstract provided.

Customer Relations Twitter @Indonesiagaruda Of Garuda Indonesia Airlines In The Social Customer Era, Ira Purwitasari, Engkus Kuswarno, Uud Wahyudin, Ninis Agustini Damayani

Library Philosophy and Practice (e-journal)

The purpose of this research is to be able to analyze in depth the airlines of. Garuda Indonesia and its public customers in establishing good relations by utilizing social media Twitter. In the current era of digital communication where the use of social media is community-based media, companies inevitably have to deal with social customers. Customer relations is a process of building long-term relationships with customers to maintain satisfaction and to keep them coming back. The research method used is descriptive qualitative. Data collection in this study consist of primary and secondary data. Primary data were carried out through in-depth …

Islamic Expression On Instagram Social Media: Marketing Communication Strategies Equestrian And Archery Tourism In Indonesia, Elan Jaelani, Lukiati Komala Erdinaya, Rohanda Rohanda, Susie Perbawasari

Library Philosophy and Practice (e-journal)

This study aims to determine the use of symbols of Islamic expression on social media Instagram as a marketing communication strategy of Equestrian and Archery Tourism in Indonesia. This research was conducted using a qualitative approach to the content analysis conducted on three official Instagram social media accounts from the three most popular Equestrian and Archery Tourism destinations in Indonesia. The results showed that most uploads on the Instagram account of equestrian and archery tourism in Indonesia display symbols of Islamic expressions, such as on images, captions, and hashtags. This study also discusses the positive responses from Instagram users to …

Controlled Vocabularies Versus Social Tags: A Brief Literature Review, Arindam Sarkar, Prof. Udayan Bhattacharya

Library Philosophy and Practice (e-journal)

The present study is a literature review, based on the comparative study between controlled vocabularies and social tags from various perspectives. Critical comments of experts on similarities, co-relationship, uses, trends between controlled vocabularies and social tags have found their manifestation in this literature review. Through this study an effort has been made to portray the overall picture of previous research regarding this topic.

#Hashtag: A Special Feature To Organize And Classify Unstructured Information In Social Media, Arindam Sarkar, Udayan Bhattacharya Prof.

Library Philosophy and Practice (e-journal)

A web based tools that allow people or companies or organizations to create, organize and share information, documents and picture/videos in virtual communities and network is called as social media. It can also be said as medium of communication like a newspaper or a radio. The facebook, twitter, Google+, Pinterest etc. are some of the absolute examples of social media. It is becoming a serious part of life as the social sites and applications are increasing. One of the most unique yet understudied feature available on social media platforms is the hashtag (#hashtag). Hashtags is a short combination of words …

Factors Influencing Job Satisfaction Among Library And Information Science Educators In South South, Nigeria, Violet Ikolo

Library Philosophy and Practice (e-journal)

Significantly, job satisfaction is influenced by different factors. This study assessed the factors influencing job satisfaction among LIS educators in South South Nigeria. Specifically, this study sought to determine the extent of satisfaction amongst LIS educators as well as identify the motivator and hygiene factors that influenced job satisfaction among LIS educators. The study used the descriptive survey design with the population made up of LIS educators from six Library Schools in South South Nigeria. The sample of 79 LIS educators were conveniently selected for the study from Library Schools in South South Nigeria. A structured questionnaire adapted from the …

Role Of Public Libraries In The Creation Of Social Capital: A Study Of Northern Nigeria, Abubakar Ladan, Rajendran P, Manickaraj J

Library Philosophy and Practice (e-journal)

ABSTRACT

Public Libraries play a vital role in the creation and bridging Social Capital. They offer a space for education, socialization and debate, which are open to the members of the society. This paper presents an overview of public libraries in Nigeria and their role, the challenges associated with the activities and programs of Nigerian Public Libraries in the creation of Social Capital. A total of 59 Public Libraries working in 12 State of Library Boards of Northern Nigeria and Federal Capital Abuja has been considered for the pilot study. The analysis has been done by frequency distribution, percentage and …

Neuroticism And Stressful Life Events: Probing Mechanisms Underlying Vulnerability To Stress-Related Depression, Erin Bondy

Arts & Sciences Electronic Theses and Dissertations

Elevated neuroticism (N) potentiates the depressogenic effects of stressful life events (SLEs). We first replicate this association using longitudinal data (N=971 older adults) from the St. Louis Personality and Aging Network (SPAN) study. Here, SLEs prospectively predicted future depressive symptoms, especially among those reporting elevated N, even after accounting for prior depressive symptoms and previous SLE exposure (NxSLE interaction: p=0.016, ΔR²=0.003). These findings were further replicated in cross-sectional analyses of the Duke Neurogenetics Study (DNS), a young adult college sample with neuroimaging data (n=1,343: NxSLE interaction: p=0.019, ΔR²=0.003). Because evidence suggests that stress may promote depression …

The Truth About Crisis Pregnancy Centers, Cassandra Griffin

Theses/Capstones/Creative Projects

This research aims to explore the practices and impacts of Crisis Pregnancy Centers (CPCs) in the United States. CPCs are centers whose primary purpose is to dissuade pregnant people from obtaining an abortion. Oftentimes they will provide services free of cost, such as ultrasounds and pregnancy tests. Their main feature is the counseling they provide against seeking abortion services. This paper explores the national affiliates of CPCs in the United States, their practices and advertising, misinformation spread by CPCs, their sources of funding and lobbying activities, and the political implications of their efforts.

A Mediational Analysis: Investigating The Role Of Academic Self-Efficacy In The Relationship Between Bullying Victimization And Depression, Rachel Elizabeth Doody

Senior Honors Projects

Bullying is one of the most pervasive problems faced during childhood. Bullying victimization has been demonstrated to be strongly associated with numerous mental health outcomes, including depression. Research suggests that self-efficacy may play a role in the relationship between bullying victimization and depressive symptoms. The present study hypothesized that academic self-efficacy would mediate this relationship. Participants (N=206, M_age = 19.5, 70.4% female) were college students who completed Bullying and Relationship Scale– Revised, Center for Epidemiologic Studies Depression Scale and the Self-Efficacy Questionnaire. Regression analyses indicated that the overall regression model was significant (β= .19, t (106) = 6.823, …

Small Group Learning Is Associated With Reduced Salivary Cortisol And Testosterone In Undergraduate Students, Kristin Snopkowski, Kathryn Demps, Ross Griffiths, Karen S. Fulk, Scott May, Kimberly Neagle, Kayla Downs, Michaela Eugster, Tessa Amend

Anthropology Faculty Publications and Presentations

Small group learning activities have been shown to improve student academic performance and educational outcomes. Yet, we have an imperfect understanding of the mechanisms by which this occurs. Group learning may mediate student stress by placing learning in a context where students have both social support and greater control over their learning. We hypothesize that one of the methods by which small group activities improve learning is by mitigating student stress. To test this, we collected physiological measures of stress and self-reported perceived stress from 26 students in two undergraduate classes. Salivary cortisol and testosterone were measured within students across …

Counseling Children From Single Parent Households, Lauren Praska

Counselor Education Capstones

No abstract provided.

The Impact Of Childhood Trauma On The Brain & Interventions For The School Counselor, Chelsea Scott

Counselor Education Capstones

No abstract provided.

Intuitive Beliefs, Jawwad Noor

Cowles Foundation Discussion Papers

Beliefs are intuitive if they rely on associative memory, which can be described as a network of associations between events. A belief-theoretic characterization of the model is provided, its uniqueness properties are established, and the intersection with the Bayesian model is characterized. The formation of intuitive beliefs is modelled after machine learning, whereby the network is shaped by past experience via minimization of the difference from an objective probability distribution. The model is shown to accommodate correlation misperception, the conjunction fallacy, base-rate neglect/conservatism, etc.

Responding To Microaggressions: Evaluation Of Bystander Intervention Strategies, Tianyi Xie

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Ethnic minorities often experience microaggressions that cause psychological distress and increase health risks. Bystander interventions are good ways to intervene when microaggressions take place and provide emotional support for ethnic minority targets. White interveners and interventions that pose low threats to White aggressors are perceived more positively than ethnic minority interveners and interventions that are more confrontational and direct. Furthermore, a support-based intervention that validates White aggressors’ good intention and effort without judgement may help White aggressors feel less defensive and more receptive to the intervention. Asian Americans face unique microaggressive themes and their racial experiences are influenced by the …

An Analysis Of The Economic Barriers To Oral Healthcare Access In Omaha, Nebraska, Elias Witte

Theses/Capstones/Creative Projects

Existing research regarding the analysis of the distribution of oral healthcare practitioners has been conducted across large metropolitan areas within the United States in order to determine the magnitude of healthcare resource deficits. Such research has demonstrated significant deficits in access to oral healthcare predominantly in lower-income urban areas. Consequently, patients in these socioeconomically disadvantaged areas have less access to routine oral care, which impacts their overall health and well-being. While there is an abundance of studies examining this issue in other localities across the country, there is a lack of information regarding the distribution of oral healthcare practitioners in …

The Impact Of A Multisensory Stimulation Environment Within A Memory Care Assisted Living Facility, Dana M. Prince

Dissertations

The use of Multisensory Stimulation Environments (MSSE) has grown increasingly more common in the United States (U.S.) as a nonpharmacological intervention for Behavioral and Psychological Symptoms of Dementia (BPSD). However, typical MSSE designs require a secluded room isolated from outside stimulation and demand direct supervision from the care provider during treatment. Due to projected shortages in the clinical workforce and the population of older adults on the rise, a study was designed to reveal the effectiveness of an open-floorplan MSSE to reduce the demand of care providers during the use of the MSSE while allowing subjects diagnosed with dementia to …