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Articles 3301 - 3330 of 39894

Full-Text Articles in Physical Sciences and Mathematics

A Decision Support System For Monitoring Livestock Diet Quality And Performance: Verification Study On Cattle, Adami Tulu, Ethiopia, A. A. Jama, G. Tolleson, J. W. Stuth, Abule Ebro, K. Zander, Robert J. Kaitho Aug 2023

A Decision Support System For Monitoring Livestock Diet Quality And Performance: Verification Study On Cattle, Adami Tulu, Ethiopia, A. A. Jama, G. Tolleson, J. W. Stuth, Abule Ebro, K. Zander, Robert J. Kaitho

IGC Proceedings (1993-2023)

Fecal profiling technology based on near infrared spectroscopy (NIRS) has been widely used in the U.S. to predict the diet quality and performance of free-ranging animals (e.g. Leite & Stuth 1995, Lyons & Stuth 1992, Lyons et al., 1993, Stuth et al., 1999, Tolleson et al., 2001). This technology is linked with the Nutritional Balance Analyzer (NUTBAL-PRO) model to form the core of a nutritional advisory system for livestock producers in the United States. This model predicts changes in body weight and condition for a broad range of livestock classes for cattle, sheep and goats. To test …


Irish Grassland Association: Delivering The Benefits From Grassland, S. Flanagan Aug 2023

Irish Grassland Association: Delivering The Benefits From Grassland, S. Flanagan

IGC Proceedings (1993-2023)

The Irish Grassland Association (IGA) is Ireland's leading forum for discussing the science of grass and animal production, the economics and finances of dairy, beef cattle and sheep farm enterprises. Membership is 800 and is a lively mix of progressive farmers (70%), research scientists, advisers and agribusiness personnel. The IGA is a member of the European Grassland Federation and has close ties with the Ulster Grassland Society, Fermanagh Grassland Club and the British Grassland Society.


The Role Of The British Grassland Society In Technology Transfer, J. M. Crichton Aug 2023

The Role Of The British Grassland Society In Technology Transfer, J. M. Crichton

IGC Proceedings (1993-2023)

Since its formation in 1945, the British Grassland Society (BGS) has been active in disseminating information to the grassland and associated sectors of agriculture and has adapted to a change from production-based agriculture to its current output mix of private and public goods. The BGS has as its remit: (a) improved production and utilisation of grass and forage crops for the promotion of agriculture and the public benefit, and (b) the advancement of education and research in grass and forage crop production and utilisation, and the publication of results.


Drivers And Dynamics Of Phytoplankton Communities And Harmful Algal Blooms In Mountain Lakes, Lara Stephanie Jansen Aug 2023

Drivers And Dynamics Of Phytoplankton Communities And Harmful Algal Blooms In Mountain Lakes, Lara Stephanie Jansen

Dissertations and Theses

Harmful cyanobacterial blooms (cyanoHABs) are a complex and widespread disturbance in freshwater water bodies, impacting water quality for wildlife and human populations. While cyanobacteria often bloom in warm lakes impacted by human development like agriculture, blooms are increasingly reported in cooler waters with limited development in the surrounding watershed. As much of cyanoHAB research has focused on lakes in highly developed watersheds, the understanding of factors leading to cyanobacteria dominance and blooms in the absence of major development remains limited. Mountain lakes can serve as ideal systems to study bloom-forming cyanobacteria in watersheds with minimal development. In addition, mountain lakes …


Representing Quantum Spins In Different Coordinate Systems For Modelling Rigid Body Orientation, Nadjet Zioui, Aicha Mahmoudi, Mohamed Tadjine Aug 2023

Representing Quantum Spins In Different Coordinate Systems For Modelling Rigid Body Orientation, Nadjet Zioui, Aicha Mahmoudi, Mohamed Tadjine

Karbala International Journal of Modern Science

Various methods for representing the spatial orientation and rotation of objects are presented and compared with the quantum bit state representation. By contrasting spherical, Euler angle, quaternion, and quantum spin coordinate systems, this work highlights important concepts regarding the rotation axis of the X gate. Several ambiguities and incomplete definitions associated with the qubit state representation are discussed, such as the spin around the qubit itself and the explanation of the considered rotation angles and signs. A mathematical analysis of the physical meaning of each eigenstate is provided along with a new comprehensive and meaningful YPR-based 3D representation of a …


Quercetin As An Anticancer Candidate For Glioblastoma Multiforme By Targeting Akt1, Mmp9, Abcb1, And Vegfa: An In Silico Study, Muhammad Hermawan Widyananda, Setyaki Kevin Pratama, Arif Nur Muhammad Ansori, Yulanda Antonius, Viol Dhea Kharisma, Ahmad Affan Ali Murtadlo, Vikash Jakhmola, Maksim Rebezov, Mars Khayrullin, Marina Derkho, Emdad Ullah, Raden Joko Kuncoroningrat Susilo, Suhailah Hayaza, Alexander Patera Nugraha, Annise Proboningrat, Amaq Fadholly, Mada Triandala Sibero, Rahadian Zainul Aug 2023

Quercetin As An Anticancer Candidate For Glioblastoma Multiforme By Targeting Akt1, Mmp9, Abcb1, And Vegfa: An In Silico Study, Muhammad Hermawan Widyananda, Setyaki Kevin Pratama, Arif Nur Muhammad Ansori, Yulanda Antonius, Viol Dhea Kharisma, Ahmad Affan Ali Murtadlo, Vikash Jakhmola, Maksim Rebezov, Mars Khayrullin, Marina Derkho, Emdad Ullah, Raden Joko Kuncoroningrat Susilo, Suhailah Hayaza, Alexander Patera Nugraha, Annise Proboningrat, Amaq Fadholly, Mada Triandala Sibero, Rahadian Zainul

Karbala International Journal of Modern Science

Quercetin, a natural compound present in various fruits and vegetables, shows promise as a potential inhibitor for glioblastoma multiforme (GBM) development. This study aims to examine the anti-GBM potential of Quercetin. The protein target of Quercetin is identified and analyzed using databases such as NCBI, SEA, CTD, and STRING. Protein-protein interaction (PPI) and functional annotation are carried out based on the obtained target proteins. Molecular docking and dynamics simulations are employed using AutoDock Vina and WebGro tools to analyze the interaction between Quercetin and its target proteins. The prediction of protein targets reveals that Quercetin directly targets four proteins associated …


Improving The Burt’S Sensitivity Using Noise Calibration Unit Via Crab Nebula Observations, Uday E. Jallod, Lana T. Ali, Hareth S. Mahdi, Kamal M. Abood Aug 2023

Improving The Burt’S Sensitivity Using Noise Calibration Unit Via Crab Nebula Observations, Uday E. Jallod, Lana T. Ali, Hareth S. Mahdi, Kamal M. Abood

Karbala International Journal of Modern Science

Radio observations from astronomical sources like supernovae became one the most important sources of information about the physical properties of those objects. However, such radio observations are affected by various types of noise such as those from sky, background, receiver, and the system itself. Therefore, it is essential to eliminate or reduce these undesired noise from the signals in order to ensure accurate measurements and analysis of radio observations. One of the most commonly used methods for reducing the noise is to use a noise calibrator. In this study, the 3-m Baghdad University Radio Telescope (BURT) has been used to …


Beauty Of Life In Dynamical Systems: Philosophical Musings And Resources For Students, Soumya Banerjee, Joyeeta Ghose, Tarakeswar Banerjee, Kalyani Banerjee Aug 2023

Beauty Of Life In Dynamical Systems: Philosophical Musings And Resources For Students, Soumya Banerjee, Joyeeta Ghose, Tarakeswar Banerjee, Kalyani Banerjee

Journal of Humanistic Mathematics

Information plays a key role in life and in complex biological systems, and dynamical systems underlie and can be used to represent many complex systems. Indeed, dynamical systems and information processing capabilities may be the hallmarks of life-like systems. In this paper we combine dynamical systems with a computational framework to generate art. The framework can be used to generate aesthetically appealing forms of life-like systems. Our work suggests that we may need an ``aesthetic sense'' to recognize life that we have not seen before. We also provide teaching resources for students in schools and undergraduate institutions.


The Importance Of Contrast Sensitivity, Color Vision, And Electrophysiological Testing In Clinical And Occupational Settings, Frances Silva Aug 2023

The Importance Of Contrast Sensitivity, Color Vision, And Electrophysiological Testing In Clinical And Occupational Settings, Frances Silva

Theses & Dissertations

Visual acuity (VA) is universally accepted as the gold standard metric for ocular vision and function. Contrast sensitivity (CS), color vision, and electrophysiological testing for clinical and occupational settings are warranted despite being deemed ancillary and minimally utilized by clinicians. These assessments provide essential information to subjectively and objectively quantify and obtain optimal functional vision. They are useful for baseline data and monitoring hereditary and progressive ocular conditions and cognitive function. The studies in this dissertation highlight the value of contrast sensitivity, color vision, and cone specific electrophysiological testing, as well as the novel metrics obtained with potential practical clinical …


Proceedings Of The 2023 Berry Summer Thesis Institute, University Of Dayton. University Honors Program Aug 2023

Proceedings Of The 2023 Berry Summer Thesis Institute, University Of Dayton. University Honors Program

Proceedings of the Berry Summer Thesis Institute

Thanks to a gift from the Berry Family Foundation and the Berry family, the University Honors Program launched the Berry Summer Thesis Institute in 2012. The institute introduces students in the University Honors Program to intensive research, scholarship opportunities and professional development. Each student pursues a 12-week summer thesis research project under the guidance of a UD faculty mentor. This contains the product of the students' research.

Contents:

  • “How Porous Materials Affect the Boundary-Layer Transition of Hypersonic Flight Vehicles” (Megan C. Sieve)
  • “Ultra-Stretchable, Self-Healing, DLP 3D-Printed Elastomers for Damage-Resistant Soft Robots: A Review” (Robert M. A. Drexler)
  • “Extrapolation of Scalar …


Nutrient Dynamics Of Freshwater Estuarine Sediments Disturbed By Dredging, Ryan Allan John Roekle Aug 2023

Nutrient Dynamics Of Freshwater Estuarine Sediments Disturbed By Dredging, Ryan Allan John Roekle

Theses and Dissertations

This study examined the nutrient environment of sediments in the Milwaukee River estuary and the dynamics of those nutrients during simulated disturbance experiments within the context of large-scale dredging remediation. Surface sediments were collected from throughout the Milwaukee estuary (including river, harbor, and nearshore stations) by PONAR, centrifuged to separate porewater (interstitial water) from solid material, and filtered to further isolate and stabilize dissolved material. Porewaters were analyzed for dissolved nutrients including ammoniacal nitrogen (AN), nitrate, nitrite, and soluble reactive phosphorus (SRP). Surface sediment porewaters within the estuary were often highly enriched in AN and SRP, which were often 10-2000x …


Distribution And Habitat Associations Of The Georgia Satyr (Neonympha Areolatus) In Arkansas, Kristi Patterson Aug 2023

Distribution And Habitat Associations Of The Georgia Satyr (Neonympha Areolatus) In Arkansas, Kristi Patterson

ATU Theses and Dissertations 2021 - Present

The Georgia satyr (Neonympha areolatus) is a small sedentary butterfly that is rare in Arkansas. Currently, the exact locations of this butterfly in Arkansas are unknown, along with the habitat characteristics associated with their presence. In order to determine these unknowns, I completed 104 surveys across seven different wildlife management areas in southern Arkansas. Pollard-Yates transects were conducted at each study site, and weather variables were recorded before each survey. Vegetation surveys were also completed at each site, and where each Georgia satyr was identified. Generalized linear models (GLM) were created to identify what parameters are important for …


A Statewide Evaluation Of Fuel Treatment Effectiveness In Altering Wildfire Outcomes On Public Lands In Utah, Jamela Charmaine Thompson Aug 2023

A Statewide Evaluation Of Fuel Treatment Effectiveness In Altering Wildfire Outcomes On Public Lands In Utah, Jamela Charmaine Thompson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Fuel treatments are land management activities that reduce living and dead flammable materials on the landscape to mitigate undesirable wildfire behavior and effects. Common treatments in the western United States include mechanical methods such as thinning and mastication, prescribed burns, and chemical methods, such as herbicide application. Treatments usually have multiple objectives, including reducing fire intensity, protecting natural and cultural resources, slowing or disrupting a potential future fire’s path, supporting ecosystem health, and reestablishing low to mid severity fire cycles in ecosystems. Although treatments can potentially modify fire behavior and ecological health, they generally cannot prevent fires from igniting, eliminate …


Growth Of Purple Sulfur Bacteria Allochromatium Vinosum On Solid Phase Metal Sulfides As Sulfur And Electron Sources, Hugo Alarcon Aug 2023

Growth Of Purple Sulfur Bacteria Allochromatium Vinosum On Solid Phase Metal Sulfides As Sulfur And Electron Sources, Hugo Alarcon

Open Access Theses & Dissertations

Purple sulfur bacteria (PSB) are photosynthetic microorganisms known for their vital roles in geochemical cycles, especially the sulfur cycle, within anoxic photic environments. PSB are also key contributors to the nitrogen, carbon, and oxygen cycles. This study focuses on the autotrophic growth of Allochromatium vinosum, a model strain of PSB, that utilize solid-phase metal sulfides (MS) as both sulfur and electron donors. Through characterizing the growth profiles of A. vinosum on pyrite (FeS2), nickel sulfide (NiS), and iron monosulfide (FeS) nanoparticles, respectively, and investigating the bacteria-MS interaction mechanisms, this work expands our current knowledge of the metabolic capabilities and flexibility …


Improving The Design And Conduct Of Aquatic Toxicity Studies With Oils Based On 20 Years Of Croserf Experience, Wa Stubblefield, M Barron, G Bragin, Me Delorenzo, B De Jourdan, B Echols, Dp French-Mccay, P Jackman, Jr Loughery, Tf Parkerton, D. Abigail Renegar, Jl Rodriguez-Gil Aug 2023

Improving The Design And Conduct Of Aquatic Toxicity Studies With Oils Based On 20 Years Of Croserf Experience, Wa Stubblefield, M Barron, G Bragin, Me Delorenzo, B De Jourdan, B Echols, Dp French-Mccay, P Jackman, Jr Loughery, Tf Parkerton, D. Abigail Renegar, Jl Rodriguez-Gil

Marine & Environmental Sciences Faculty Articles

Laboratory toxicity testing is a key tool used in oil spill science, spill effects assessment, and mitigation strategy decisions to minimize environmental impacts. A major consideration in oil toxicity testing is how to replicate real-world spill conditions, oil types, weathering states, receptor organisms, and modifying environmental factors under laboratory conditions. Oils and petroleum-derived products are comprised of thousands of compounds with different physicochemical and toxicological properties, and this leads to challenges in conducting and interpreting oil toxicity studies. Experimental methods used to mix oils with aqueous test media have been shown to influence the aqueous-phase hydrocarbon composition and concentrations, hydrocarbon …


Computational Analysis Of Antibody Binding Mechanisms To The Omicron Rbd Of Sars-Cov-2 Spike Protein: Identification Of Epitopes And Hotspots For Developing Effective Therapeutic Strategies, Mohammed Alshahrani Aug 2023

Computational Analysis Of Antibody Binding Mechanisms To The Omicron Rbd Of Sars-Cov-2 Spike Protein: Identification Of Epitopes And Hotspots For Developing Effective Therapeutic Strategies, Mohammed Alshahrani

Computational and Data Sciences (PhD) Dissertations

The advent of the Omicron strain of SARS-CoV-2 has elicited apprehension regarding its potential influence on the effectiveness of current vaccines and antibody treatments. The present investigation involved the implementation of mutational scanning analyses to examine the impact of Omicron mutations on the binding affinity of four categories of antibodies that target the Omicron receptor binding domain (RBD) of the Spike protein. The study demonstrates that the Omicron variant harbors 23 unique mutations across the RBD regions I, II, III, and IV. Of these mutations, seven are shared between RBD regions I and II, while three are shared among RBD …


Exploring Experimental Design And Multivariate Analysis Techniques For Evaluating Community Structure Of Bacteria In Microbiome Data, Kelsey Karnik Aug 2023

Exploring Experimental Design And Multivariate Analysis Techniques For Evaluating Community Structure Of Bacteria In Microbiome Data, Kelsey Karnik

Department of Statistics: Dissertations, Theses, and Student Work

The gut microbiome plays a crucial role in human health, and by working collaboratively with microbiologists, we aim to further our understanding of the human gut and its impact on human health. Promoting a diverse microbiome is emphasized throughout microbiology literature, and involving a statistician in designing experiments to relate gut bacteria and some measured health outcome is crucial for ensuring valid and accurate results. By adopting new experimental design and analysis methods, researchers can begin to gain a deeper understanding of how the genetics of our food affect the composition of taxa within the gut microbiome. This dissertation is …


Overcoming Barriers To Aquatic Plant Restoration: Addressing Gaps In Species Identification And Planting Techniques In The Intermountain West, Kate A. Sinnott Aug 2023

Overcoming Barriers To Aquatic Plant Restoration: Addressing Gaps In Species Identification And Planting Techniques In The Intermountain West, Kate A. Sinnott

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Aquatic ecosystems provide many critical and economically valuable benefits, including drinking water, food, recreational opportunities, and water supply for irrigation and agriculture. However, the health of these systems has been severely impacted by human activities such as pollution, land conversion, and introductions of harmful species. Restoring native aquatic plants can help reverse this damage and reestablish benefits, though it is not a common practice. With an objective to increase capacity for aquatic plant restoration in the Intermountain West, I identified and addressed two major barriers: 1) a lack of confidence in aquatic species identification among wetland professionals, and 2) underdeveloped …


Opening The Black Box: Soil Microbial Communities In Field-Based Plant-Soil Feedback Experiments, Julia Kate Aaronson Aug 2023

Opening The Black Box: Soil Microbial Communities In Field-Based Plant-Soil Feedback Experiments, Julia Kate Aaronson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Plant-soil feedback is a process through which plants modify the properties of their associated soils, affecting their growth. PSF can play a key role in regulating plant growth and communities including altering plant invasion, rarity, and abundance. However, our understanding of the soil organisms that drive these plant growth responses is limited. Most studies treat soils as a ‘black box’ and do little to reveal which specific microbes or microbial communities may be responsible. This chapter examines two recent large PSF field experiments conducted in Minnesota, USA, and Jena, Germany. These experiments revealed that plants altered their soils, changing subsequent …


A Mechanistic Examination Of Interspecific Competition Between Wild And Domestic Herbivores, Courtney Check Aug 2023

A Mechanistic Examination Of Interspecific Competition Between Wild And Domestic Herbivores, Courtney Check

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Large herbivores, such as mule deer and cattle have similar life histories and likely compete for resources. However, quantifying the extent to which these species compete and the specific resources they compete for has proved challenging. My research examines if cattle influence deer abundance and behavior due to competition for forage, competition for shade, and/or by affecting the predation risk of deer. Using a grid of autonomous trail cameras, I was able to determine if cattle abundance influences local deer abundance in relation to specific resources and habitat features. Using GPS data from collared deer, I was also able to …


Analyzing The Adoption, Cropping Rotation, And Impact Of Winter Cover Crops In The Mississippi Alluvial Plain (Map) Region Through Remote Sensing Technologies, Zobaer Ahmed Aug 2023

Analyzing The Adoption, Cropping Rotation, And Impact Of Winter Cover Crops In The Mississippi Alluvial Plain (Map) Region Through Remote Sensing Technologies, Zobaer Ahmed

Graduate Theses and Dissertations

This dissertation explores the application of remote sensing technologies in conservation agriculture, specifically focusing on identifying and mapping winter cover crops and assessing voluntary cover crop adoption and cropping patterns in the Arkansas portion of the Mississippi Alluvial Plain (MAP). In the first chapter, a systematic review using the PRISMA methodology examines the last 30 years of thematic research, development, and trends in remote sensing applied to conservation agriculture from a global perspective. The review uncovers a growing interest in remote sensing-based research in conservation agriculture and emphasizes the necessity for further studies dedicated to conservation practices. Among the 68 …


Geometric Morphometric Analysis Of Modern Viperid Vertebrae Facilitates Identification Of Fossil Specimens, Lance D. Jessee Aug 2023

Geometric Morphometric Analysis Of Modern Viperid Vertebrae Facilitates Identification Of Fossil Specimens, Lance D. Jessee

Electronic Theses and Dissertations

Snake vertebrae are common in the fossil record, whereas cranial remains are generally fragile and rare. Consequently, vertebrae are the most commonly studied fossil element of snakes. However, identification of snake vertebrae can be problematic due to extensive variation. This study utilizes 2-D geometric morphometrics and canonical variates analysis to 1) reveal variation between genera and species and 2) classify vertebrae of modern and fossil eastern North American Agkistrodon and Crotalus. The results show that vertebrae of Agkistrodon and Crotalus can reliably be classified to genus and species using these methods. Based on the statistical analyses, four of the …


Isolation And Structural Determination Of Bioactive Metabolites From The Soil Bacterium, Arthrobacter Sp. Tajx1902, Amonah Arije Aug 2023

Isolation And Structural Determination Of Bioactive Metabolites From The Soil Bacterium, Arthrobacter Sp. Tajx1902, Amonah Arije

Electronic Theses and Dissertations

As antimicrobial resistance persistently disrupts the treatment of microbial infection, natural product chemistry has played a significant role in identifying novel drugs with novel modes of action critical to getting ahead of resistance. The primary goal of this project is to extract and identify potential novel antimicrobial natural products produced by Arthrobacter sp. Although underexplored, Arthrobacter sps. have been known to produce bioactive compounds with versatility; one such is a depsipeptide with quorum-sensing inhibitory activity.1 In this research, an Arthrobacter sp. TAJX1902, isolated from a soil sample, showed inhibitory activity against a filamentous indicator bacterium and a violacein-producing Janthinobacterium …


The Ecological Effects Of Nitrogen Enrichment In Aridlands, Jennifer Holguin Aug 2023

The Ecological Effects Of Nitrogen Enrichment In Aridlands, Jennifer Holguin

Open Access Theses & Dissertations

Anthropogenic nitrogen (N) deposition is one of the most prominent factors driving global change. Across the globe, N deposition has driven major changes in terrestrial ecosystems, such as declines in plant biodiversity, enhanced exotic plant growth, and changes to biogeochemical processes involved in carbon and nutrient cycling. While noteworthy effort has been put forth to investigate the effects of N deposition on terrestrial ecosystems, a disproportionate number of N addition studies have been conducted in temperate mesic systems. Thus, we lack a holistic and mechanistic understanding of how N deposition impact aridland ecosystems. Additionally, our predictions of the effects of …


Integrating Sensor Development, Risk Assessment, And Community Engagement To Support Environmental Justice In The Rural Community Of El Tiple, Colombia, David Bahamon Pinzon Aug 2023

Integrating Sensor Development, Risk Assessment, And Community Engagement To Support Environmental Justice In The Rural Community Of El Tiple, Colombia, David Bahamon Pinzon

All Dissertations

In Colombia, ethnic communities have traditionally been responsible stewards of natural resources. They recognize the importance of these resources for their livelihood, as well as their ancestral and cultural heritage. El Tiple, a rural Afro-Colombian community, has been affected by the incursion of private corporations that promoted the expansion of sugarcane monocrops in their territory. Since the introduction of the monoculture industry, local freshwater sources have been depleted due to intensive water use for irrigation of the sugarcane crops. Additionally, the intensive usage of agrochemicals has been linked with loss of native flora, damages to family farms, and pollution of …


Insights Into The Characteristics Of Outdoor Recreationists In Utah From A Statewide Survey, Jordan W. Smith, Nate Trauntvein, Casey Trout Aug 2023

Insights Into The Characteristics Of Outdoor Recreationists In Utah From A Statewide Survey, Jordan W. Smith, Nate Trauntvein, Casey Trout

Environment and Society Faculty Publications

Understanding the characteristics and preferences of outdoor recreationists in Utah can inform the administrative, funding, and management decisions of the many entities who provide outdoor recreation opportunities within the state. There is currently a lack of data on characteristics, preferences, and opinions of the state’s outdoor recreating public. As one component of the analysis supporting the development of the state’s outdoor recreation strategic plan, we launched a short online survey to begin to address this need. The survey was administered in spring of 2023 to an online panel of individuals who indicated that they are current residents of Utah and …


Studying The Stability Of Collagen/Heparin Coatings To Be Used In Cell Therapy Applications, Gavin Mussino Aug 2023

Studying The Stability Of Collagen/Heparin Coatings To Be Used In Cell Therapy Applications, Gavin Mussino

Biological Sciences Undergraduate Honors Theses

This honors thesis aims to investigate the reusability and performance of cell coatings for cell therapy applications. Cell therapy, which involves the use of human cells to repair or replace damaged tissues, holds immense potential for medical advancements. However, ensuring the survival and functionality of transplanted cells remains a significant challenge. We focused on studying the effectiveness of coatings applied to cells for improved cell growth and viability. The research project involved the preparation of the coatings using a layer-by-layer method and the subsequent seeding of cells. The coated cells were then subjected to a series of experiments to assess …


Visual Complexity Of The Time-Frequency Image Pinpoints The Epileptogenic Zone: An Unsupervised Deep-Learning Tool To Analyze Interictal Intracranial Eeg, Sarvagya Gupta Aug 2023

Visual Complexity Of The Time-Frequency Image Pinpoints The Epileptogenic Zone: An Unsupervised Deep-Learning Tool To Analyze Interictal Intracranial Eeg, Sarvagya Gupta

Graduate Masters Theses

Epilepsy, a prevalent neurological disorder characterized by recurrent seizures, continues to pose significant challenges in diagnosis and treatment, particularly among children. Despite substantial advancements in medical technology and treatment modalities, localization of the part of brain that causes seizures (Epileptogenic Zone) remains a difficult task. Intracranial EEG (iEEG) is often used to estimate the epileptogenic zone (EZ) in children with drugresistant epilepsy (DRE) and target it during surgery. Conventionally, iEEG signals are inspected in the time domain by human experts aiming to locate epileptiform activity.

Visual scrutiny of the iEEG time-frequency (TF) images can be an alternative way to review …


The Effect Of Package Types On Fresh Peaches In The Direct-To-Consumer Distribution Environment, Brennan Lytle Aug 2023

The Effect Of Package Types On Fresh Peaches In The Direct-To-Consumer Distribution Environment, Brennan Lytle

All Theses

The direct-to-consumer (DTC) shipping mode presents new opportunity for fresh peach sales in North America where demand over the past four decades has steadily declined. The hazards in this distribution mode are severe, and fresh peaches are fragile emphasizing the need for proper protection. A full analysis that not only encompasses the effects of the direct-to-consumer distribution environment, but also incorporates analyses of the environmental and economic impact of the packages utilized for transit of peaches is necessary. In this study, we use the metrics of peach grade, firmness, soluble solids concentration, and percent softness before and after the distribution …


Leveraging Eco-Evolutionary Models For Gene Drive Risk Assessment, Matthew A. Combs, Andrew J. Golnar, Justin M. Overcash, Alun L. Lloyd, Keith R. Hayes, David A. O'Brochta, Kim M. Pepin Aug 2023

Leveraging Eco-Evolutionary Models For Gene Drive Risk Assessment, Matthew A. Combs, Andrew J. Golnar, Justin M. Overcash, Alun L. Lloyd, Keith R. Hayes, David A. O'Brochta, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Engineered gene drives create potential for both widespread benefits and irreversible harms to ecosystems. CRISPR-based systems of allelic conversion have rapidly accelerated gene drive research across diverse taxa, putting field trials and their necessary risk assessments on the horizon. Dynamic processbased models provide flexible quantitative platforms to predict gene drive outcomes in the context of system-specific ecological and evolutionary features. Here, we synthesize gene drive dynamic modeling studies to highlight research trends, knowledge gaps, and emergent principles, organized around their genetic, demographic, spatial, environmental, and implementation features. We identify the phenomena that most significantly influence model predictions, discuss limitations of …