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Articles 6271 - 6300 of 11849

Full-Text Articles in Physical Sciences and Mathematics

Volume 10, Taylor Hogg, Tiffany Carter, Brandyn Johnson, Haleigh James, Josh Baker, Tyler Cernak, Kirsten Bauer, Allie Snavely, Mary Zell Galen, Eric Powell, Thomas Wise, Katie Kinsey, Beth Barbolla, Maeleigh Ferlet, Rebecca Morra, Michala Day, Alexandra Evangelista, Max Flores, Harley Hodges, Clardene Jones, Harrison Samaniego, Jamesha Watson, Abby Gargiulo, Heather Green, Haley Klepatzki, Juan Guevara, Dani Bondurant, Michael Joseph Link Jr., Pamela Dahl, Maeve Losen, Charlotte Murphey Apr 2018

Volume 10, Taylor Hogg, Tiffany Carter, Brandyn Johnson, Haleigh James, Josh Baker, Tyler Cernak, Kirsten Bauer, Allie Snavely, Mary Zell Galen, Eric Powell, Thomas Wise, Katie Kinsey, Beth Barbolla, Maeleigh Ferlet, Rebecca Morra, Michala Day, Alexandra Evangelista, Max Flores, Harley Hodges, Clardene Jones, Harrison Samaniego, Jamesha Watson, Abby Gargiulo, Heather Green, Haley Klepatzki, Juan Guevara, Dani Bondurant, Michael Joseph Link Jr., Pamela Dahl, Maeve Losen, Charlotte Murphey

Incite: The Journal of Undergraduate Scholarship

Introduction Dr. Roger A. Byrne

An Analysis of Media Framing in Cases of Violence Against Women by Taylor Hogg

Writing in the Discipline of Nursing by Tiffany Carter

Photography by Brandyn Johnson

The Hidden Life of Beef Cattle: A Study of Cattle Welfare on Traditional Ranches and Industrial Farms by Haleigh James

Bloodworth's by Josh Baker and Tyler Cernak

Prosimians: Little Bodies, Big Significance by Kirsten Bauer

Skinformed by Allie Snavely

Coopertition and Gracious Professionalism: The Effects of First Robotics Folklore and Culture on the Stem Community by Mary Zell Galen

Tilt by Eric Powell And Thomas Wise

The Millennial …


Hyperpolarization Of Silicon Nanoparticles With Tempo Radicals, Jingzhe Hu, Nicholas Whiting, Pratip Bhattacharya Mar 2018

Hyperpolarization Of Silicon Nanoparticles With Tempo Radicals, Jingzhe Hu, Nicholas Whiting, Pratip Bhattacharya

Nicholas Whiting

Silicon-based particles can be hyperpolarized via dynamic nuclear polarization to enhance 29Si magnetic resonance signals. Application of this technique to nanoscale silicon particles has been limited because of the low signal enhancements achieved; it is hypothesized that this is due to the low number of endogenous electronic defects inherent to the particles. We introduce a method of incorporating exogenous radicals into silicon nanoparticle suspensions in order to improve the hyperpolarization of 29Si nuclear spins to levels sufficient for in vivo MR imaging. Calibration of radical concentrations and polarization times are reported for a variety of silicon particle sizes (30−200 nm …


Self-Reported Risk And Delinquent Behavior And Problem Behavioral Intention In Hong Kong Adolescents: The Role Of Moral Competence And Spirituality, Daniel T. L. Shek, Xiaoqin Zhu Mar 2018

Self-Reported Risk And Delinquent Behavior And Problem Behavioral Intention In Hong Kong Adolescents: The Role Of Moral Competence And Spirituality, Daniel T. L. Shek, Xiaoqin Zhu

Pediatrics Faculty Publications

Based on the six-wave data collected from Grade 7 to Grade 12 students (N = 3,328 at Wave 1), this pioneer study examined the development of problem behaviors (risk and delinquent behavior and problem behavioral intention) and the predictors (moral competence and spirituality) among adolescents in Hong Kong. Individual growth curve models revealed that while risk and delinquent behavior accelerated and then slowed down in the high school years, adolescent problem behavioral intention slightly accelerated over time. After controlling the background socio-demographic factors, moral competence and spirituality were negatively associated with risk and delinquent behavior as well as problem …


The Role Of Nutrition In Influencing Mechanisms Involved In Environmentally Mediated Diseases, Bernhard Hennig, Michael C. Petriello, Mary V. Gamble, Young-Joon Surh, Laura A. Kresty, Norbert Frank, Nuchanart Rangkadilok, Mathuros Ruchirawat, William A. Suk Mar 2018

The Role Of Nutrition In Influencing Mechanisms Involved In Environmentally Mediated Diseases, Bernhard Hennig, Michael C. Petriello, Mary V. Gamble, Young-Joon Surh, Laura A. Kresty, Norbert Frank, Nuchanart Rangkadilok, Mathuros Ruchirawat, William A. Suk

Superfund Research Center Faculty Publications

Human exposure to environmental contaminants such as persistent chlorinated organics, heavy metals, pesticides, phthalates, flame retardants, electronic waste and airborne pollutants around the world, and especially in Southeast Asian regions, are significant and require urgent attention. Given this widespread contamination and abundance of such toxins as persistent organic pollutants (POPs) in the ecosystem, it is unlikely that remediation alone will be sufficient to address the health impacts associated with this exposure. Furthermore, we must assume that the impact on health of some of these contaminants results in populations with extraordinary vulnerabilities to disease risks. Further exacerbating risk; infectious diseases, poverty …


Analyzing The Efficiency Of Reforestation Efforts In Regaining Carbon Storage In A Costa Rican Cloud Forest, Elvin Irihamye Mar 2018

Analyzing The Efficiency Of Reforestation Efforts In Regaining Carbon Storage In A Costa Rican Cloud Forest, Elvin Irihamye

Student Research Conference Select Presentations

Forests hold an important place in offsetting carbon emissions, absorbing nearly 40 percent of man-made fossil fuel emissions every year. Over the last 100 years, the effects of deforestation have crippled our forest’s ability to store excess carbon, leading to drastic atmospheric change. Efforts to regrow deforested forests have increased rapidly to address issues like climate change. There is thus a need to analyze current efforts at regaining carbon storage, a critical component to maintaining atmospheric homeostasis. Accordingly, we traveled to the Cloudbridge Nature Reserve in San Gerardo, Costa Rica to aggregate data on the carbon storage capabilities across three …


Berikut 3 Nama Obat Sipilis Yang Di Jual Di Apotik, Maka Roni Mar 2018

Berikut 3 Nama Obat Sipilis Yang Di Jual Di Apotik, Maka Roni

maka roni

Berikut 3 Nama obat sipilis yang di jual di apotik - Kalo Sodara melakukan pengobatan sipilis memalui medis,biasanya anda akan mendapatkan resep obat antibiotik yang harus ditebus di apotik,biasanya beda dokter untuk antibiotik yag diberikan juga berbeda beda,banyak orang yang cocok tapi banyak juga yang tidak cocok,berikut penjelasannya Berikut 3 Nama obat sipilis yang di jual di apotik


Data Analysis Basics – Part Ii, Judith A. Savageau Mar 2018

Data Analysis Basics – Part Ii, Judith A. Savageau

Judith A. Savageau

Blog post to AEA365, a blog sponsored by the American Evaluation Association (AEA) dedicated to highlighting Hot Tips, Cool Tricks, Rad Resources, and Lessons Learned for evaluators. The American Evaluation Association is an international professional association of evaluators devoted to the application and exploration of program evaluation, personnel evaluation, technology, and many other forms of evaluation. Evaluation involves assessing the strengths and weaknesses of programs, policies, personnel, products, and organizations to improve their effectiveness.


Data Analysis Basics – Part I, Judith A. Savageau Mar 2018

Data Analysis Basics – Part I, Judith A. Savageau

Judith A. Savageau

Blog post to AEA365, a blog sponsored by the American Evaluation Association (AEA) dedicated to highlighting Hot Tips, Cool Tricks, Rad Resources, and Lessons Learned for evaluators. The American Evaluation Association is an international professional association of evaluators devoted to the application and exploration of program evaluation, personnel evaluation, technology, and many other forms of evaluation. Evaluation involves assessing the strengths and weaknesses of programs, policies, personnel, products, and organizations to improve their effectiveness.


Radiological Decontamination In The Urban Environment Utilizing An Irreversible Wash-Aid Recovery System, Keith A. Sanders Mar 2018

Radiological Decontamination In The Urban Environment Utilizing An Irreversible Wash-Aid Recovery System, Keith A. Sanders

Theses and Dissertations

The radioactive fallout from the Fukushima Daiichi nuclear reactors accident and the ongoing threat of nuclear or radioactive terrorism have forced the need for urban radiological decontamination into the forefront. Many of the established decontamination techniques are not ideally suited for the urban milieu. One of the keys to maximize the effectiveness of long-term remediation and recovery in the urban environment is immediate mitigation within a few days of the incident and before a rain event. The Integrated Wash-Aid, Treatment, and Emergency Reuse System (IWATERS) provides a potentially safe and effective method for early responders and remediation teams to perform …


2018-02-08-Video-00000297 (3).Mp4, Padmanaban Krishnan Mar 2018

2018-02-08-Video-00000297 (3).Mp4, Padmanaban Krishnan

Padmanaban Krishnan

This is a video of a Vacuum Dough Expansion System


Dietary Inflammatory Index And Type 2 Diabetes Mellitus In Adults: The Diabetes Mellitus Survey Of Mexico City, Edgar Denova-Gutiérrez, Paloma Muñoz-Aguirre, Nitin Shivappa, James R. Hébert, Lizbeth Tolentino-Mayo, Carolina Batis, Simón Barquera Mar 2018

Dietary Inflammatory Index And Type 2 Diabetes Mellitus In Adults: The Diabetes Mellitus Survey Of Mexico City, Edgar Denova-Gutiérrez, Paloma Muñoz-Aguirre, Nitin Shivappa, James R. Hébert, Lizbeth Tolentino-Mayo, Carolina Batis, Simón Barquera

Faculty Publications

Diet and inflammation are both associated with type 2 diabetes mellitus (T2DM). In the present study, we aimed to assess the relation between the dietary inflammatory index (DII) and the presence of T2DM in Mexican adults participating in the Diabetes Mellitus Survey administered in Mexico City (DMS-MC). The study involved 1174 subjects (48.5% men) between 20–69 years of age. A validated semi-quantitative food frequency questionnaire was employed to evaluate dietary intake and to compute DII. The DII is based on scientific evidence about the association between dietary compounds and six established inflammatory biomarkers. Multivariate logistic regression models were used to …


Perceived Access And Barriers To Care Among Illicit Drug Users And Hazardous Drinkers: Findings From The Seek, Test, Treat, And Retain Data Harmonization Initiative (Sttr)., Mika Matsuzaki, Quan M Vu, Marya Gwadz, Joseph A C Delaney, Irene Kuo, Maria Esther Perez Trejo, William E Cunningham, Chinazo O Cunningham, Katerina Christopoulos Mar 2018

Perceived Access And Barriers To Care Among Illicit Drug Users And Hazardous Drinkers: Findings From The Seek, Test, Treat, And Retain Data Harmonization Initiative (Sttr)., Mika Matsuzaki, Quan M Vu, Marya Gwadz, Joseph A C Delaney, Irene Kuo, Maria Esther Perez Trejo, William E Cunningham, Chinazo O Cunningham, Katerina Christopoulos

Epidemiology Faculty Publications

BACKGROUND: Illicit drug use (DU) and hazardous drinking (HD) among marginalized populations may be associated with greater barriers to care.

METHODS: We used baseline data on the participants of the Seek, Test, Treat, and Retain data harmonization initiative. DU includes use of any illicit drugs within the past 6 months. HD was defined as scores ≥8 for men and ≥ 7 for women on Alcohol Use Disorders Identification Test within the past 12 months. Social support scores were assigned by summing scores from individual questions related to social support. Two outcomes for multivariable regression models and mediation analysis were perceived …


Erratum: Reducing Cascading Failure Risk By Increasing Infrastructure Network Interdependence, Mert Korkali, Jason G. Veneman, Brian F. Tivnan, James P. Bagrow, Paul D.H. Hines Mar 2018

Erratum: Reducing Cascading Failure Risk By Increasing Infrastructure Network Interdependence, Mert Korkali, Jason G. Veneman, Brian F. Tivnan, James P. Bagrow, Paul D.H. Hines

College of Engineering and Mathematical Sciences Faculty Publications

This corrects the article DOI: 10.1038/srep44499.


A Chimeric Nucleobase - Phenylazo Derivative As An Intrinsic Nucleobase Quencher, Gyeongsu Park, Timothy Martin-Chan, Amer El Samm, Robert H.E. Hudson Mar 2018

A Chimeric Nucleobase - Phenylazo Derivative As An Intrinsic Nucleobase Quencher, Gyeongsu Park, Timothy Martin-Chan, Amer El Samm, Robert H.E. Hudson

Western Research Forum

Molecular beacons are important bioanalytical probes which are most often

constructed from a single-stranded oligonucleotide which has been labeled at

opposite termini with a fluorophore and a quencher. When the fluorophore and

quencher are in close proximity, no fluorescence is observed due to FRET

(Fluorescence Resonance Energy Transfer). DABCYL (4-dimethylaminoazobenzene-

4'-carboxylic acid) has been used as a quencher in the molecular beacon to absorbs

excitation energy from a fluorophore and to dissipate the energy as heat. However,

DABCYL is unable to form a base-pair and is conventionally placed as an overhanging

residue. This produces a derivative wherein the chromophore has …


Defining Care Patterns And Outcomes Among Persons Living With Hiv In Washington, Dc: Linkage Of Clinical Cohort And Surveillance Data., Amanda D Castel, Arpi Terzian, Jenevieve Opoku, Lindsey Powers Happ, Naji Younes, Michael Kharfen, Alan Greenberg, Dc Cohort Executive Committee Mar 2018

Defining Care Patterns And Outcomes Among Persons Living With Hiv In Washington, Dc: Linkage Of Clinical Cohort And Surveillance Data., Amanda D Castel, Arpi Terzian, Jenevieve Opoku, Lindsey Powers Happ, Naji Younes, Michael Kharfen, Alan Greenberg, Dc Cohort Executive Committee

Epidemiology Faculty Publications

BACKGROUND: Triangulation of data from multiple sources such as clinical cohort and surveillance data can help improve our ability to describe care patterns, service utilization, comorbidities, and ultimately measure and monitor clinical outcomes among persons living with HIV infection.

OBJECTIVES: The objective of this study was to determine whether linkage of clinical cohort data and routinely collected HIV surveillance data would enhance the completeness and accuracy of each database and improve the understanding of care patterns and clinical outcomes.

METHODS: We linked data from the District of Columbia (DC) Cohort, a large HIV observational clinical cohort, with Washington, DC, Department …


Preparation, Modification, Characterization, And Biosensing Application Of Nanoporous Gold Using Electrochemical Techniques, Jay Bhattarai, Dharmendra Neupane, Bishal Nepal, Vasilii Mikhaylov, Alexei Demchenko, Keith Stine Mar 2018

Preparation, Modification, Characterization, And Biosensing Application Of Nanoporous Gold Using Electrochemical Techniques, Jay Bhattarai, Dharmendra Neupane, Bishal Nepal, Vasilii Mikhaylov, Alexei Demchenko, Keith Stine

Chemistry & Biochemistry Faculty Works

Nanoporous gold (np-Au), because of its high surface area-to-volume ratio, excellent conductivity, chemical inertness, physical stability, biocompatibility, easily tunable pores, and plasmonic properties, has attracted much interested in the field of nanotechnology. It has promising applications in the fields of catalysis, bio/chemical sensing, drug delivery, biomolecules separation and purification, fuel cell development, surface-chemistry-driven actuation, and supercapacitor design. Many chemical and electrochemical procedures are known for the preparation of np-Au. Recently, researchers are focusing on easier and controlled ways to tune the pores and ligaments size of np-Au for its use in different applications. Electrochemical methods have good control over fine-tuning …


Preparation, Modification, Characterization, And Biosensing Application Of Nanoporous Gold Using Electrochemical Techniques, Jay Bhattarai, Dharmendra Neupane, Bishal Nepal, Vasilii Mikhaylov, Alexei Demchenko, Keith Stine Mar 2018

Preparation, Modification, Characterization, And Biosensing Application Of Nanoporous Gold Using Electrochemical Techniques, Jay Bhattarai, Dharmendra Neupane, Bishal Nepal, Vasilii Mikhaylov, Alexei Demchenko, Keith Stine

Alexei Demchenko

Nanoporous gold (np-Au), because of its high surface area-to-volume ratio, excellent conductivity, chemical inertness, physical stability, biocompatibility, easily tunable pores, and plasmonic properties, has attracted much interested in the field of nanotechnology. It has promising applications in the fields of catalysis, bio/chemical sensing, drug delivery, biomolecules separation and purification, fuel cell development, surface-chemistry-driven actuation, and supercapacitor design. Many chemical and electrochemical procedures are known for the preparation of np-Au. Recently, researchers are focusing on easier and controlled ways to tune the pores and ligaments size of np-Au for its use in different applications. Electrochemical methods have good control over fine-tuning …


Global Stability For A 2n+1 Dimensional Hiv Aids Epidemic Model With Treatments, Olusegun M. Otunuga Mar 2018

Global Stability For A 2n+1 Dimensional Hiv Aids Epidemic Model With Treatments, Olusegun M. Otunuga

Olusegun Michael Otunuga

In this work, we derive and analyze a 2n+1-dimensional deterministic differential equation modeling the transmission and treatment of HIV (Human Immunodeficiency Virus) disease. The model is extended to a stochastic differential equation by introducing noise in the transmission rate of the disease. A theoretical treatment strategy of regular HIV testing and immediate treatment with Antiretroviral Therapy (ART) is investigated in the presence and absence of noise. By defining $R_{0,n}$, $R_{t,n}$ and $\mathcal{R}_{t,n}$ as the deterministic basic reproduction number in the absence of ART treatments, deterministic basic reproduction number in the presence of ART treatments and stochastic reproduction number …


In Place: March 12, 2018, Place Mar 2018

In Place: March 12, 2018, Place

PLACE Historical Documents

In PLACE is a newsletter designed to keep the Linfield College community apprised of information related to PLACE activities, as well as ways to bring the program into classes. Included in this issue:

  • Spotlight On: Leadership and the Liberal Arts Skills Development Series
  • Upcoming Events
  • The Last Weeks in PLACE


Design And Implementation Of A Ferrocement Improved Cookstove In Rural Panama, Josh Donegan Mar 2018

Design And Implementation Of A Ferrocement Improved Cookstove In Rural Panama, Josh Donegan

USF Tampa Graduate Theses and Dissertations

Household air pollution contributes to the premature death of more than 4 million people annually. Improved cookstoves are one technological intervention that can potentially reduce exposure to household air pollution. However, improved cookstove implementation programs need to consider measures to increase sustainability and promote long-term adoption. The objectives of this research were 1) to develop and implement a new ferrocement cookstove for Peña Blanca, a rural indigenous community in the Ngäbe-Bugle region of Panama, 2) to evaluate its potential sustainability in comparison to the most common cooking technologies observed in the community, 3) to prepare a construction manual for the …


Use Of Excel Spreadsheet Calculators In Handling Data Generated From Uv- Spectrometer, Mercy Okezue, Kari Clase, Steve Byrn Mar 2018

Use Of Excel Spreadsheet Calculators In Handling Data Generated From Uv- Spectrometer, Mercy Okezue, Kari Clase, Steve Byrn

BIRS Symposium

To ease the complexities of handling data generated from different analytical procedures, validated excel spreadsheet containing relevant formulas are developed to ensure the process of data handling will consistently produce the expected results. This paper introduces the use of Excel spreadsheets in handling data generated from using a UV-Spectrometer in determination of analyte concentration in various dosage forms


Instituting Process Control Mechanisms In A Quality Control Analytical Chemistry Laboratory, Mercy Okezue, Kari Lynn Clase, Stephen Byrn Mar 2018

Instituting Process Control Mechanisms In A Quality Control Analytical Chemistry Laboratory, Mercy Okezue, Kari Lynn Clase, Stephen Byrn

BIRS Symposium

Statistical Process Control by means of using control charts was a means of monitoring performance of analytical equipment. Quality control checks on test items using these equipment generated data used for plotting X-bar charts. The charts generated had warning and control limits which helped monitor system performance


Effectiveness Of Biocide Substitution And Management Plan Implementation For The Control Of, Adelmarie Bones Mar 2018

Effectiveness Of Biocide Substitution And Management Plan Implementation For The Control Of, Adelmarie Bones

USF Tampa Graduate Theses and Dissertations

After the notorious outbreak and discovery of Legionella bacteria in 1976, the waterborne pathogen was added to the list of disease-causing agents associated with the built environment. Legionella pneumophila was discovered when it was identified as the agent that caused 34 deaths and an outbreak of pneumonia-like symptoms in several attendees of the 1976 American Legion Convention held in Philadelphia (OSHA, 2017).

Recently published data from the year 2015 reported more than 6,000 Legionnaires’ cases identified in the United States (CDC, 2016). This is a concerning number given that one in every ten infected persons will die of the disease. …


The Role Of Ehealth In Disasters: A Strategy For Education, Training And Integration In Disaster Medicine, Anthony C. Norris, Jose J. Gonzalez, David T. Parry, Richard E. Scott, Julie Dugdale, Deepak Khazanchi Mar 2018

The Role Of Ehealth In Disasters: A Strategy For Education, Training And Integration In Disaster Medicine, Anthony C. Norris, Jose J. Gonzalez, David T. Parry, Richard E. Scott, Julie Dugdale, Deepak Khazanchi

Information Systems and Quantitative Analysis Faculty Publications

This paper describes the origins and progress of an international project to advance disaster eHealth (DEH) – the application of eHealth technologies to enhance the delivery of healthcare in disasters. The study to date has focused on two major themes; the role of DEH in facilitating inter-agency communication in disaster situations, and the fundamental need to promote awareness of DEH in the education of disaster managers and health professionals. The paper deals mainly with on-going research on the second of these themes, surveying the current provision of disaster medicine education, the design considerations for a DEH programme for health professionals, …


An Empirical Study Of Chronic Diseases In The United States: A Visual Analytics Approach To Public Health, Wullianallur Raghupathi, Viju Raghupathi Mar 2018

An Empirical Study Of Chronic Diseases In The United States: A Visual Analytics Approach To Public Health, Wullianallur Raghupathi, Viju Raghupathi

Publications and Research

In this research we explore the current state of chronic diseases in the United States, using data from the Centers for Disease Control and Prevention and applying visualization and descriptive analytics techniques. Five main categories of variables are studied, namely chronic disease conditions, behavioral health, mental health, demographics, and overarching conditions. These are analyzed in the context of regions and states within the U.S. to discover possible correlations between variables in several categories. There are widespread variations in the prevalence of diverse chronic diseases, the number of hospitalizations for specific diseases, and the diagnosis and mortality rates for different states. …


Response To Kabisch And Colleagues, Jesse T. Rieb, Rebecca Chaplin-Kramer, Gretchen C. Daily, Paul R. Armsworth, Katrin Böhning-Gaese, Aletta Bonn, Graeme S. Cumming, Felix Eigenbrod, Volker Grimm Mar 2018

Response To Kabisch And Colleagues, Jesse T. Rieb, Rebecca Chaplin-Kramer, Gretchen C. Daily, Paul R. Armsworth, Katrin Böhning-Gaese, Aletta Bonn, Graeme S. Cumming, Felix Eigenbrod, Volker Grimm

Rubenstein School of Environment and Natural Resources Faculty Publications

No abstract provided.


Telotristat Ethyl In Carcinoid Syndrome: Safety And Efficacy In The Telecast Phase 3 Trial, Marianne Pavel, David J. Gross, Marta Benavent, Petros Perros, Raj Srirajaskanthan, Richard R. P. Warner, Matthew H. Kulke, Lowell B. Anthony, Pamela L. Kunz, Dieter Hörsch, Martin O Weickert, Pablo Lapuerta, Wenjun Jiang, Kenneth Kassler-Taub, Suman Wason, Rosanna Fleming, Douglas Fleming, Rocio Garcia-Carbonero Mar 2018

Telotristat Ethyl In Carcinoid Syndrome: Safety And Efficacy In The Telecast Phase 3 Trial, Marianne Pavel, David J. Gross, Marta Benavent, Petros Perros, Raj Srirajaskanthan, Richard R. P. Warner, Matthew H. Kulke, Lowell B. Anthony, Pamela L. Kunz, Dieter Hörsch, Martin O Weickert, Pablo Lapuerta, Wenjun Jiang, Kenneth Kassler-Taub, Suman Wason, Rosanna Fleming, Douglas Fleming, Rocio Garcia-Carbonero

Internal Medicine Faculty Publications

Telotristat ethyl, a tryptophan hydroxylase inhibitor, was efficacious and well tolerated in the phase 3 TELESTAR study in patients with carcinoid syndrome (CS) experiencing ≥ 4 bowel movements per day (BMs/day) while on somatostatin analogs (SSAs). TELECAST, a phase 3 companion study, assessed the safety and efficacy of telotristat ethyl in patients with CS (diarrhea, flushing, abdominal pain, nausea or elevated urinary 5-hydroxyindoleacetic acid (u5-HIAA)) with < 4 BMs/day on SSAs (or ≥ 1 symptom or ≥ 4 BMs/day if not on SSAs) during a 12-week double-blind treatment period followed by a 36-week open-label extension (OLE). The primary safety and efficacy endpoints were incidence of treatment-emergent adverse events (TEAEs) and percent change from baseline in 24-h u5-HIAA at week 12. Patients (N = 76) were randomly assigned (1:1:1) to receive placebo or telotristat ethyl 250 mg or 500 mg 3 times per day (tid); 67 continued receiving telotristat ethyl 500 mg tid during the OLE. …


The Santa Clara, 2018-03-01, Santa Clara University Mar 2018

The Santa Clara, 2018-03-01, Santa Clara University

The Santa Clara

No abstract provided.


The Functional Specialties: A Workshop On Applying Lonergan, Praxis Program Of The Advanced Seminar On Mission, Seton Hall University Mar 2018

The Functional Specialties: A Workshop On Applying Lonergan, Praxis Program Of The Advanced Seminar On Mission, Seton Hall University

Praxis Conference and Workshop Proceedings

These are the proceedings of the Praxis Program of the Advanced Seminar on Mission’s third annual summer workshop which was held in Trieste, Italy in July 2017. It focused on the application of Bernard Lonergan’s Functional Specialties to the work of the Seton Hall University faculty participants. The workshop was jointly sponsored by the Center for Vocation and Servant Leadership and the Center for Catholic Studies, and co-sponsored by Boston College, the Jacques Maritain Institute and the University of Trieste.


A Spline-Assisted Semiparametric Approach To Nonparametric Measurement Error Models, Fei Jiang, Yanyuan Ma Mar 2018

A Spline-Assisted Semiparametric Approach To Nonparametric Measurement Error Models, Fei Jiang, Yanyuan Ma

COBRA Preprint Series

Nonparametric estimation of the probability density function of a random variable measured with error is considered to be a difficult problem, in the sense that depending on the measurement error prop- erty, the estimation rate can be as slow as the logarithm of the sample size. Likewise, nonparametric estimation of the regression function with errors in the covariate suffers the same possibly slow rate. The traditional methods for both problems are based on deconvolution, where the slow convergence rate is caused by the quick convergence to zero of the Fourier transform of the measurement error density, which, unfortunately, appears in …