Physical Sciences and Mathematics Commons^™

Flavin Oxidation In Flavin-Dependent N-Monooxygenases, Reeder M. Robinson, Catherine A. Klancher, Pedro J. Rodriguez, Pablo Sobrado

Chemistry Faculty Research & Creative Works

Siderophore A (SidA) from Aspergillus fumigatus is a flavin-containing monooxygenase that hydroxylates ornithine (Orn) at the amino group of the side chain. Lysine (Lys) also binds to the active site of SidA; however, hydroxylation is not efficient and H₂O₂ is the main product. The effect of pH on steady-state kinetic parameters was measured and the results were consistent with Orn binding with the side chain amino group in the neutral form. From the pH dependence on flavin oxidation in the absence of Orn, a pKa value >9 was determined and assigned to the FAD-N5 atom. In the …

Predictive Analysis Of Real-Time Strategy Games Using Graph Mining, Isam Abdulmunem Alobaidi

Doctoral Dissertations

"Machine learning and computational intelligence have facilitated the development of recommendation systems for a broad range of domains. Such recommendations are based on contextual information that is explicitly provided or pervasively collected. Recommendation systems often improve decision-making or increase the efficacy of a task. Real-Time Strategy (RTS) video games are not only a popular entertainment medium, they also are an abstraction of many real-world applications where the aim is to increase your resources and decrease those of your opponent. Using predictive analytics, which examines past examples of success and failure, we can learn how to predict positive outcomes for such …

Cis/Trans Energetics In Epoxide, Thiirane, Aziridine And Phosphirane Containing Cyclopentanols: Effects Of Intramolecular Oh···O,S,N And P Contacts, Ben E. Smith, Jeremy M. Carr, Gregory S. Tschumper

Chemistry Faculty Research & Creative Works

A recent computational analysis of the stabilizing intramolecular OH···O contact in 1,2-dialkyl-2,3-epoxycyclopentanol diastereomers has been extended to thiiriane, aziridine and phosphirane analogues. Density functional theory (DFT), second-order Møller-Plesset perturbation theory (MP2) and CCSD(T) coupled-cluster computations with simple methyl and ethyl substituents indicate that electronic energies of the cis isomers are lowered by roughly 3 to 4 kcal mol⁻¹ when the OH group of these cyclopentanol systems forms an intramolecular contact with the O, S, N or P atom on the adjacent carbon. The results also suggest that S and P can participate in these stabilizing intramolecular interactions as effectively …

Three-Dimensional Nanotube Arrays For Solar Energy Harvesting And Production Of Solar Fuels, Wipula P. R. Liyanage

Doctoral Dissertations

"Over the past decade extensive research has been carried out on photovoltaic semiconductors to provide a solution towards a renewable energy future. Fabricating high-efficiency photovoltaic devices largely rely on nanostructuring the photoabsorber layers due to the ability of improving photoabsorption, photocurrent generation and transport in nanometer scale. Vertically aligned, highly uniform nanorods and nanowire arrays for solar energy conversion have been explored as potential candidates for solar energy conversion and solar-fuel generation owing to their enhanced photoconversion efficiencies.

However, controlled fabrication of nanorod and especially nanotube arrays with uniform size and shape and a pre-determined distribution density is still a …

Volumetric Error Compensation For Industrial Robots And Machine Tools, Le Ma

Doctoral Dissertations

“A more efficient and increasingly popular volumetric error compensation method for machine tools is to compute compensation tables in axis space with tool tip volumetric measurements. However, machine tools have high-order geometric errors and some workspace is not reachable by measurement devices, the compensation method suffers a curve-fitting challenge, overfitting measurements in measured space and losing accuracy around and out of the measured space. Paper I presents a novel method that aims to uniformly interpolate and extrapolate the compensation tables throughout the entire workspace. By using a uniform constraint to bound the tool tip error slopes, an optimal model with …

Origin Of Periclines In The Ozark Plateau, Missouri: A Field And Numerical Modeling, Chao Liu

Doctoral Dissertations

"A series upright sub-horizontal folds in sandstones of the early Ordovician Roubidoux Formation are exposed in road cuts along US Highway 63 in the northern part of the Salem Plateau of central Missouri for over a distance of approximately 10 km. These folds are in marked contrast to the more typical horizontal to sub-horizontal Ordovician strata of the Ozark Plateau. The origin of those folds remains enigmatic. The inspection of the characteristics of these folds using stereographic analysis revealed a non-cylindrical geometrical pattern than a near cylindrical fold. Structural data of 54 folds indicate an alternating basin and dome pattern. …

Novel Statistical Modeling Of Sleep Patterns In Drosophila Melanogaster, Luyang Wang

Doctoral Dissertations

”Sleep is one of the most important behaviors in animals, yet many aspects of sleep are not well understood. In humans, sleep has been shown to impact different aspects of health and cognitive performance. The fruit fly, Drosophila melanogaster, can be used as a model organism to investigate sleep patterns over an entire lifespan. The sleep-wake status can be recorded every minute over the life of individual flies, resulting in a wealth of data for identifying meaningful aspects of sleep. In this work, a framework based on statistical modeling methods is developed for sleep data collected on fruit flies …

Receiver Function Investigations Of Mantle Transition Zone And Crustal Structure In East Africa And Northeast Asia, Muchen Sun

Doctoral Dissertations

"In spite of numerous geophysical studies have been conducted in East Africa and Northeast Asia, the structure and evolution of the crust, upper mantle, and the mantle transition zone (MTZ) are still controversial. The MTZ discontinuities beneath the study area are imaged by stacking an unprecedented volume of receiver functions (RFs). The normal MTZ thickness beneath the Western Branch of the EARS and Tanzania Craton indicates the absence of present-day thermal upwelling from the lower mantle. In contrast, beneath the Eastern Branch, a significant MTZ thinning reveals the existence of thermal upwelling from either the upper MTZ or the lower …

Investigating Blast Fume Propagation, Concentration And Clearance In Underground Mines Using Computational Fluid Dynamics (Cfd), Raymond Ninnang Tiile

Doctoral Dissertations

"Blasting activities using standard industry explosives is an essential component of underground hard rock mining operations. Blasting operations result in the release of noxious gases, presenting both safety and productivity threats. Overestimation of post-blast re-entry time results in production losses, while underestimation leads to injuries and fatalities. Research shows that most underground mines simply standardize post-blast re-entry times based on experiences and observations. Few underground mines use theoretical methods for calculating post-blast re-entry time. These theoretical methods, however, are unable to account for the variations in the blasting conditions. Literature review shows that: (i) there is currently no means of …

Accurate Monitoring Of X, Y, And Z Magnetization For Analysis Of Hardware And Pulse Sequence Performance In Nmr Spectroscopy, Emmalou Theresa Schmittzehe

Doctoral Dissertations

"A new nuclear magnetic resonance (NMR) imaging protocol has been developed to independently record the x, y, and z components of the nuclear net magnetization at any point in a pulse sequence while eliminating the observation of the other components. This protocol provides an experimental method of tracking magnetization which then can be used in conjunction with theoretical models to scrutinize the predicted outcome of each step in an NMR pulse sequence and potentially find further improvements to their effectiveness and efficiency. The protocol utilizes a rapid rotating-frame imaging pulse-train technique to obtain RF-field (B₁) and resonance-offset (ΔB …

Modeling Of Hiv, Sir And Sis Epidemics On Time Scales And Oscillation Theory, Gülşah Yeni

Doctoral Dissertations

"We study higher dimensional systems of first order dynamic equations on time scales together with their applications. In particular, we focus on epidemic models such as HIV (Human Immunodeficiency Virus), SIS (Susceptible-Infected-Susceptible) and SIR (Susceptible-Infected-Recovered).

First, we generalize the early studied continuous three dimensional linear model of drug therapy for HIV-1 decline on time scales in order to derive new discrete models that predict the total concentration of plasma virus as a function of time. We compare these models to explore the impact of the theory of time scales. After fitting the models to the data collected at a clinical …

Archaeological Investigation Using Geophysical Methods To Locate Historic Byram's Ford Road, Marshall Seth Foster

Masters Theses

"Ground penetrating radar, a time domain electromagnetic metal detector and a frequency domain electromagnetic metal detector were used with the goal of locating a section of the Byram's Ford Road believed to be intersecting the historic Big Blue Battlefield in the Westport area of Kansas City, Missouri.

Ground penetrating data were acquired at three sites, Site A, Site B, and Site C. The time domain EM metal detector was used to acquire data at Site A, where subsequent ground truthing was conducted using the frequency domain EM metal detector and an excavation tool. Significant anomalies were visible on both the …

Less Is More: Beating The Market With Recurrent Reinforcement Learning, Louis Kurt Bernhard Steinmeister

Masters Theses

"Multiple recurrent reinforcement learners were implemented to make trading decisions based on real and freely available macro-economic data. The learning algorithm and different reinforcement functions (the Differential Sharpe Ratio, Differential Downside Deviation Ratio and Returns) were revised and the performances were compared while transaction costs were taken into account. (This is important for practical implementations even though many publications ignore this consideration.) It was assumed that the traders make long-short decisions in the S&P500 with complementary 3-month treasury bill investments. Leveraged positions in the S&P500 were disallowed. Notably, the Differential Sharpe Ratio and the Differential Downside Deviation Ratio are risk …

Evaluation Of Naturally Occurring And Anthropogenic Contamination In Missouri Streams, Christina Jane Sehrt

Masters Theses

"The goal of this study is to observe the values and variability of water quality parameters and benthic macroinvertebrates in watersheds with very little anthropogenic impact and to compare these values with those acquired in watersheds with more anthropogenic impact. The following five HUC 12-digit watersheds had very little anthropogenic impact and were considered "pristine": Rogers Creek, Mill Creek, Middle West Fork-Black River, Bee Fork, and Ottery Creek. Five largely urban sub-basins were also considered; these basins are: Grand Glaize Creek, Glaize Creek, Sugar Creek, Hominy Creek, and Grindstone Creek. For each watershed, both water quality parameters and benthic macroinvertebrates …

Impact Of Framing And Base Size Of Computer Security Risk Information On User Behavior, Xinhui Zhan

Masters Theses

"This research examines the impact of framing and base size of computer security risk information on users' risk perceptions and behavior (i.e., download intention and download decision). It also examines individual differences (i.e., demographic factors, computer security awareness, Internet structural assurance, self-efficacy, and general risk-taking tendencies) associated with users' computer security risk perceptions. This research draws on Prospect Theory, which is a theory in behavioral economics that addresses risky decision-making, to generate hypotheses related to users' decision-making in the computer security context. A 2 x 3 mixed factorial experimental design (N = 178) was conducted to assess the effect of …

Advanced Techniques For Improving Canonical Genetic Programming, Adam Tyler Harter

Masters Theses

"Genetic Programming (GP) is a type of Evolutionary Algorithm (EA) commonly employed for automated program generation and model identification. Despite this, GP, as most forms of EA's, is plagued by long evaluation times, and is thus generally reserved for highly complex problems. Two major impacting factors for the runtime are the heterogeneous evaluation time for the individuals and the choice of algorithmic primitives. The first paper in this thesis utilizes Asynchronous Parallel Evolutionary Algorithms (APEA) for reducing the runtime by eliminating the need to wait for an entire generation to be evaluated before continuing the search. APEA is applied to …

Reprocessing And Comparison Of The 2 Hz And 10 Hz Vertical Component Seismic Data Of The Blackfoot 3c-2d Survey, Mete Sarikaya

Masters Theses

"The Blackfoot seismic 3C-2D data were obtained from the Consortium for Research in Elastic Wave Exploration Seismology (CREWES) Project in 1995. The seismic data acquisition was performed in the Blackfoot Field, which is around 15 km southeast of Strathmore, Alberta. The 4 Hz and 10 Hz vertical component data are reprocessed to increase the quality and resolution of the seismic images. The Glauconitic sand reservoir at approximately 1.1 s, and a strong reflection about at 1.5 s are the focuses of the study.

The processing procedure includes different parameters and methods to obtain the best seismic sections of 2 Hz …

U-Pb Detrital Zircon Geochronology Of Paleozoic Clastics Of The Ozark Plateau: Implication For Sea-Level Fluctuations And Far-Field Tectonics, Chen Zhao

Masters Theses

"The Ozark Plateau of south-central Missouri is underlain by Ordovician to Pennsylvanian carbonate and clastic strata. Enigmatic, presumably Pennsylvanian 'filled sink' structures are common on the Ozark Plateau and remain a source of controversy. We present results for U-Pb ages of detrital zircons for 13 samples from the OP. We use U-Pb ages from other Paleozoic clastics and 'filled sinks' on the OP, to suggest: 1) FSS record a period of Middle Ordovician erosion and sedimentation and 2) document significant shifts in sediment provenance that reflect regional tectonic events affecting the North American Craton.

The KDE plots of normalized detrital …

The Correlation Between Sleep And Lifespan In Drosophila Melanogaster, Joshua Randall Lisse

Masters Theses

”Adequate sleep is associated with an individual’s health. Too little sleep is associated with many health problems, including cardiovascular disease, obesity, and a general increase in all-cause mortality. Yet the molecular changes that link poor sleep and changes in health are still not well understood. Individuals have a unique daily need for sleep, and deviations from the animal’s regular sleeping patterns can be indicative of, or result in, underlying changes in its health. Therefore, we hypothesize that changes in the sleep architecture in Drosophila melanogaster reflect changes in the fly’s health.

We determined sleep architecture in wild-type male flies over …

Development Of A Switchable Radioisotope Generator, Kyle Mitchell Paaren

Doctoral Dissertations

The Switchable Radioisotope Generator utilizes alpha-induced reactions to produce a combination of photons, neutrons, and protons with varying fluxes dependent on target materials and source geometry. The activity/strength of the secondary radiation is further controlled by manipulating the number of alpha particles that can interact with the target material(s). Analytical equations were solved to confirm secondary radiation production from target materials using average cross sections from TENDL data. TENDL and JENDL data was confirmed by analytically solving for the total alpha-induced cross sections. This information was used to produce the provisional and utility Patent No: US20190013109A1. TENDL data was then …

Seismic Attribute Assisted Depositional Facies Identification And Stratigraphic Correlation In The Central Gulf Coast Region Of Texas, Yani Lin

Doctoral Dissertations

"The sandstone deposits in the fluvial-dominated delta systems in the Lower Wilcox Group above the Cretaceous carbonate shelf edges of the Texas Gulf Coast Region are considered as high exploration potential reservoir bodies. However, the multi-phase regression and transgression during the late Paleocene to the early Eocene complicate the local depositional structure. The depositional facies is hard to be identified in details using the traditional seismic stratigraphic interpretation method. Seismic attributes are effective in detecting depositional facies, especially in mapping channels and investigating reservoir characteristics. In this study, we utilize seismic attributes to identify the principal depositional facies in the …

Reliability Analysis For Systems With Outsourced Components, Zhengwei Hu

Doctoral Dissertations

"The current business model for many industrial firms is to function as system integrators, depending on numerous outsourced components from outside component suppliers. This practice has resulted in tremendous cost savings; it makes system reliability analysis, however, more challenging due to the limited component information available to system designers. The component information is often proprietary to component suppliers. Motivated by the need of system reliability prediction with outsourced components, this work aims to explore feasible ways to accurately predict the system reliability during the system design stage. Four methods are proposed. The first method reconstructs component reliability functions using limited …

Privacy Preservation In Social Media Environments Using Big Data, Katrina Ward

Doctoral Dissertations

"With the pervasive use of mobile devices, social media, home assistants, and smart devices, the idea of individual privacy is fading. More than ever, the public is giving up personal information in order to take advantage of what is now considered every day conveniences and ignoring the consequences. Even seemingly harmless information is making headlines for its unauthorized use (18). Among this data is user trajectory data which can be described as a user's location information over a time period (6). This data is generated whenever users access their devices to record their location, query the location of a point …

Provenance And Depositional Environments Of The Upper Permian-Lowermost Triassic Fluvial And Lacustrine Sandstones, Wutonggou Low-Order Cycle, Bogda Mountains, Nw China, Dongyu Zheng

Doctoral Dissertations

"This work integrates petrographic and fieldwork studies and documents the spatial and temporal distributions of compositions and textures of the upper Permian-lowermost Triassic fluvial-lacustrine sandstones, Wutonggou low-order cycle (WTG LC), Bogda Mountains, NW China. In the first part, three petrofacies are identified on the basis of the relative abundances of quartz, feldspar, and lithics and conglomerate compositions and paleocurrent directions are documented. These data indicate that rocks of the eastern North Tianshan Suture (ENTS) and rift shoulders were the provenance lithology. Moreover, the upsection changes of petrofacies and conglomerate compositions suggest that the lithology of ENTS changed. During approximately Wuchiapingian, …

Electrodeposition Of Epitaxial Metal Thin Films On Silicon For Energy Conversion And Flexible Electronics, Qingzhi Chen

Doctoral Dissertations

"This research focuses on epitaxial electrodeposition of two coinage metals: Au and Ag thin films on the silicon surface and their applications in flexible electronics and energy conversion and storage. The first paper: Photoelectrochemistry of ultrathin, semi-transparent, and catalytic gold films electrodeposited epitaxially onto n-silicon (111) describes the epitaxial electrodeposition of Au thin films on n-type Si using a simple HAuCl4 bath and the photoelectrochemical properties of the Au-Si junction barrier. The effect of the Au layer on the interfacial energetics as well as the stability of the photoelectrode as a function of the Au coverage/thickness is determined in a …

Coherent Effects In Wave Propagation Through Complex Media, Milan Koirala

Doctoral Dissertations

"Diffusion is a powerful and versatile description of a typical wave propagation in a random scattering medium that disregards phase and, thus, a possibility of interference. Speckle, transmission fluctuations, wave localization, non-local correlations, and transmission eigenchannels are examples of persistent interference effects, which arise in the course of deterministic propagation. Such wave phenomena contain a wealth of information about the medium and the source of waves, enabling sensing and coherent control of the propagation. The nonlocal correlations and speckle statistics of the partially coherent light are used to uncover an object hidden by a diffusive cloak inside a strong scattering …

Nanomorphology Dependent Optical And Mechanical Properties Of Aerogels, Chandana Mandal

Doctoral Dissertations

"Aerogels are very low density, light weight open pore materials. A hypothesis that is under intense current investigation by the scientific community states that the mechanical properties of nanostructured polymers depend on their nanomorphology. Aerogels are nanostructured ultra-lightweight nanoporous materials with skeletal frameworks that can display a wide range of nanomorphologies. Thereby aerogels comprise a suitable platform for testing not only that hypothesis but also a wide range of other properties such as light scattering for applications, for example, in thermally insulating windows.

To study the mechanical properties of nanostructured matter as a function of nanomorphology, various shape-memory polyurethane aerogels …

Synthesis And Applications Of Ceramic (Silicon Carbide And Silicon Nitride), Metallic (Cobalt(0)) And Polymeric (Polyurethane) Aerogels, Parwani M. Rewatkar

Doctoral Dissertations

"A new method has been demonstrated for the synthesis of monolithic ceramic and purely metallic aerogels from xerogel powder compacts, and the use of polyurethane aerogels based on cyclodextrins as efficient desiccants.

I. Highly porous ( > 80%) monolithic SiC and Si₃N₄, aerogels were prepared from compressed compacts of polyurea-crosslinked silica xerogel powders. The process is time efficient as solvent-exchange through powders is fast, and energy efficient as it bypasses drying with supercritical fluids. The final ceramic objects were chemically pure, sturdy, with compressive moduli at 37 ±7 MPa and 59 ± 7 MPa, and thermal conductivities …

High Level Thermochemical And Spectroscopic Computations For Molecules Relevant To Combustion And The Atmosphere, Bradley K. Welch

Doctoral Dissertations

"Computational thermochemistry can be a complicated multistep process, but in recent years has become an equal partner with experiment. Many important molecules in combustion systems or in the atmosphere (such as short-lived radicals) are difficult to study experimentally. Predicting highly accurate thermochemistry is a key aspect in understanding these species. In this project, computational thermochemistry was developed into an automated streamlined procedure and then used to understand the methyl and ethyl peroxy families of radicals. This effort involved optimizing a standard workflow for computational thermochemistry. Computational thermochemistry generally requires numerous individual calculations whose cost and scalings vary widely. Conducting such …

Decoding The History Of The Early Solar System Using Comet Volatile Compositions, Nathaniel Xavier Roth

Doctoral Dissertations

"Understanding the evolution of the solar system, as well as its current volatile content, requires knowledge of the initial conditions present in the solar nebula. As some of the first objects to accrete in the solar nebula, cometary nuclei are among the most primitive remnants of solar system formation, and their present-day volatile composition likely reflects the composition and conditions where (and when) they formed. As such, the volatile compositions of cometary nuclei may serve as 'fossils' of solar system formation. High-resolution near-infrared spectroscopy offers a valuable tool for sampling the primary volatile (i.e., ices subliming directly from the nucleus) …