Physical Sciences and Mathematics Commons^™

A Partitioned Approach For Computing Fluid-Structure Interaction, With Application To Tumor Modeling And Simulation, Asim Timalsina

Mathematics & Statistics Theses & Dissertations

Modeling and Simulation plays a critical role in understanding complex physical and biological phenomena as it provides an efficient and controlled test environment, without the risk of costly experiments and clinical trials. In this dissertation, we present an extensive study of two such systems with integrated application: Fluid structure interaction (FSI) and virotherapy on tumor. Moreover, we substantiate a few preliminary results of FSI application on tumor.

The FSI problem comprises of fluid forces exerted on the solid body and the motion of the structure affecting the fluid flow. FSI problems are of great interest to applied industries, however they …

Characterization Of 3-Ester And 3-Carbamate Derivatives Of N-Acetyl-D-Glucosamine And Their Use In Controlled Drug Delivery, Consuelo Garcia

Chemistry & Biochemistry Theses & Dissertations

Low molecular weight gelators (LMWGs) are a class of compounds which reversibly form a network that traps solvents to form gels. Gelation by LMWGs is driven solely by non-covalent interactions such as hydrogen bonding, π - π stacking, and hydrophobic interactions. LMWGs can be designed such that the gel-sol and sol-gel transitions happen as a response to a specific stimulus. These stimulus responsive gels or “smart” gels can be used in a wide variety of applications including tissue regeneration, biosensing, and controlled drug delivery.

Among the different types of compounds that are LMWGs, carbohydrate based systems are especially interesting. Carbohydrates …

Lignin Contribution To The Global Carbon Pool: Investigating The Abiotic Modification Of Lignin By Reactive Oxygen Species, Derek Charles Waggoner

Chemistry & Biochemistry Theses & Dissertations

Evidence suggests that reactive oxygen species (ROS), largely generated through photochemical processes, are important in transforming the chemical composition of the large pool of terrestrially-derived dissolved organic matter (DOM) exported from land to water annually. However, due to the challenges inherent in isolating the effects of individual ROS on DOM composition, the role of ROS in the photochemical alteration of DOM remains poorly characterized. The main focus of the studies within this dissertation aim to more thoroughly characterize the alterations to lignin, used as an analog for terrestrial DOM, resulting from reactions with ROS.

To investigate the possibility that the …

Observations Of Greenhouse Gas Isotopologues With Ace-Fts And Waccm, Eric Michael Buzan

Chemistry & Biochemistry Theses & Dissertations

Increases in greenhouse gas concentrations in the atmosphere are the major driver of climate change. Quantifying the sources and sinks of these gases is a major focus of research. Measuring isotopologues, or molecules that differ in isotopic composition, is one useful way of constraining the budget of a molecule as they are highly sensitive to different sources and sinks. However, measurements above the surface have been restricted to a few locations and have only reached the lower stratosphere. Satellite-based remote sensing can achieve nearly global measurement coverage, but so far no satellites have measured isotopologues.

Presented here are measurements of …

Mipas Imk/Iaa Carbon Tetrachloride (Ccl4) Retrieval And First Comparison With Other Instruments, Ellen Eckert, Thomas Von Clarmann, Alexandra Laeng, Gabriele P. Stiller, Bernd Funke, Norbert Glatthor, Udo Grabowski, Sylvia Kellmann, Michael Kiefer, Andrea Linden, Peter F. Bernath

Chemistry & Biochemistry Faculty Publications

MIPAS thermal limb emission measurements were used to derive vertically resolved profiles of carbon tetrachloride (CCl₄). Level-1b data versions MIPAS/5.02 to MIPAS/5.06 were converted into volume mixing ratio profiles using the level-2 processor developed at Karlsruhe Institute of Technology (KIT) Institute of Meteorology and Climate Research (IMK) and Consejo Superior de Investigaciones Cientificas (CSIC), Instituto de Astrofisica de Andalucia (IAA). Consideration of peroxyacetyl nitrate (PAN) as an interfering species, which is jointly retrieved, and CO₂ line mixing is crucial for reliable retrievals. Parts of the CO₂ Q-branch region that overlap with the CCl₄ signature were …

Higher-Twist Corrections To Gluon Tmd Factorization, I. Balitsky, A. Tarasov

Physics Faculty Publications

We calculate power corrections to TMD factorization for particle production by gluon-gluon fusion in hadron-hadron collisions.

Robustness Of Observation-Based Decadal Sea Level Variability In The Indo-Pacific Ocean, A. G. Nidheesh, M. Lengaigne, J. Vialard, T. Izumo, A. S. Unnikrishnan, B. Meyssignac, B. Hamlington, C. De Boyer Montegut

OES Faculty Publications

We examine the consistency of Indo-Pacific decadal sea level variability in 10 gridded, observation-based sea level products for the 1960-2010 period. Decadal sea level variations are robust in the Pacific, with more than 50% of variance explained by decadal modulation of two flavors of El Nino-Southern Oscillation (classical ENSO and Modoki). Amplitude of decadal sea level variability is weaker in the Indian Ocean than in the Pacific. All data sets indicate a transmission of decadal sea level signals from the western Pacific to the northwest Australian coast through the Indonesian throughflow. The southern tropical Indian Ocean sea level variability is …

Perspective: The Physics, Diagnostics, And Applications Of Atmospheric Pressure Low Temperature Plasma Sources Used In Plasma Medicine, M. Laroussi

Electrical & Computer Engineering Faculty Publications

Low temperature plasmas have been used in various plasma processing applications for several decades. But it is only in the last thirty years or so that sources generating such plasmas at atmospheric pressure in reliable and stable ways have become more prevalent. First, in the late 1980s, the dielectric barrier discharge was used to generate relatively large volume diffuse plasmas at atmospheric pressure. Then, in the early 2000s, plasma jets that can launch cold plasma plumes in ambient air were developed. Extensive experimental and modeling work was carried out on both methods and much of the physics governing such sources …

Nuclear Chiral Axial Currents And Applications To Few-Nucleon Systems, Alessandro Baroni

Physics Theses & Dissertations

This Thesis is divided into three main parts. The first part discusses basic aspects of chiral effective field theory and the formalism, based on time ordered perturbation theory, used to to derive the nuclear potentials and currents from the chiral Lagrangians. The second part deals with the actual derivation, up to one loop, of the two-nucleon potential and one- and two-nucleon weak axial charge and current. In both derivations ultraviolet divergences generated by loop corrections are isolated using dimensional regularization. The resulting axial current is finite and conserved in the chiral limit, while the axial charge requires renormalization. A complete …

Instrument Design Optimization With Computational Methods, Michael H. Moore

Physics Theses & Dissertations

Using Finite Element Analysis to approximate the solution of differential equations, two different instruments in experimental Hall C at the Thomas Jefferson National Accelerator Facility are analyzed. The time dependence of density fluctuations from the liquid hydrogen (LH2) target used in the Q_weak experiment (2011-2012) are studied with Computational Fluid Dynamics (CFD) and the simulation results compared to data from the experiment. The 2.5 kW liquid hydrogen target was the highest power LH2 target in the world and the first to be designed with CFD at Jefferson Lab. The first complete magnetic field simulation of the Super High Momentum …

Test Of New Readout Electronics For The Bonus12 Experiment, Mathieu Ehrhart

Physics Theses & Dissertations

For decades, electron-proton scattering experiments have been providing a large amount of data on the proton structure function. However, because of the instability of free neutrons, fewer experiments have been able to study the neutron structure function. The BONuS collaboration at Jefferson Laboratory addresses this challenge by scattering electrons off a deuterium target, using a RTPC capable of detecting the low-momentum spectator protons near the target. Events of electrons scattering on almost free neutrons are selected by constraining the spectator protons to very low momenta and very backward scattering angles. In 2005, BONuS successfully measured the neutron structure with scattering …

Investigating Physical Processes Associated With Chesapeake Bay And Changjiang Estuary, Arash Niroomandi

Civil & Environmental Engineering Theses & Dissertations

Coastal and estuaries are landforms that not only have great impacts on large marine ecosystem, but also play a significant role in moderating or aggravating natural hazards and erosion risks that are expected to increase with climate change. This dissertation explores some of the concerns associated with coasts and coastal systems. In the second chapter, a thirty seven year wave hindcast (1979-2015) in Chesapeake Bay using NCEP's Climate Forecast System Reanalysis (CFSR) wind is presented. The long-term significant wave heights are generated by the third-generation nearshore wave model SWAN, which is validated using the wave height measurements at buoy stations …

Hampton Roads Residents’ Perceptions Of Sea Level Rise And Flooding Adaptation, Juita-Elena (Wie) Yusuf, Carol Considine, Burton St. John Iii, Michelle Covi, J. Gail Nicula, Pragati Rawat, Kaitlin Giles

Occasional Paper Series

No abstract provided.

Comment On "Using An Adcp To Estimate Turbulent Kinetic Energy Dissipation Rate In Sheltered Coastal Waters", Ann E. Gargett

CCPO Publications

Greene et al. revisit the suggestion that the turbulent kinetic energy dissipation rate could be estimated through a "large-eddy estimate," employing acoustic measurements of velocity fields associated with the largest energy-containing scales of ocean turbulence. While the large-eddy estimate as originally proposed used vertical velocity and a vertical eddy length scale, Greene et al. chose instead to substitute a horizontal length scale for the latter. This comment argues that combining a horizontal scale for length with a vertical velocity scale produces a large-eddy estimate of the dissipation rate that is accurate only if the energy-containing eddies are isotropic, and that …

Depletion Of Ozone And Reservoir Species Of Chlorine And Nitrogen Oxide In The Lower Antarctic Polar Vortex Measured From Aircraft, T. Jurkat, C. Voigt, S. Kaufmann, J.-U. Grooß, H. Ziereis, A. Dörnbrack, P. Hoor, H. Bozem, A. Engel, H. Bönisch, P. F. Bernath

Chemistry & Biochemistry Faculty Publications

Novel airborne in situ measurements of inorganic chlorine, nitrogen oxide species, and ozone were performed inside the lower Antarctic polar vortex and at its edge in September 2012. We focus on one flight during the Transport and Composition of the LMS/Earth System Model Validation (TACTS/ESMVal) campaign with the German research aircraft HALO (High-Altitude LOng range research aircraft), reaching latitudes of 65°S and potential temperatures up to 405 K. Using the early winter correlations of reactive trace gases with N₂O from the Atmospheric Chemistry Experiment-Fourier Transform Spectrometer (ACE-FTS), we find high depletion of chlorine reservoir gases up to ∼40% …

Rosenbluth Separation Of The Π0 Electroproduction Cross Section Off The Neutron, M. Mazouz, Z. Ahmed, H. Albataineh, K. Allada, K. A. Aniol, V. Bellini, M. Benali, W. Boeglin, P. Bertin, M. Canan, C. E. Hyde, S. Koirala, M. N. H. Rashad

Physics Faculty Publications

We report the first longitudinal-transverse separation of the deeply virtual exclusive π⁰ electroproduction cross section off the neutron and coherent deuteron. The corresponding four structure functions dσ_L/dt, dσ_T/dt, dσ_LT/dt, and dσ_TT/dt are extracted as a function of the momentum transfer to the recoil system at Q² = 1.75 GeV² and x_B = 0.36. The ed -> edπ⁰ cross sections are found compatible with the small values expected from theoretical models. The en -> enπ⁰ cross sections show a dominance from the response to transversely polarized …

Scalable And Fully Distributed Localization In Large-Scale Sensor Networks, Miao Jin, Su Xia, Hongyi Wu, Xianfeng David Gu

Electrical & Computer Engineering Faculty Publications

This work proposes a novel connectivity-based localization algorithm, well suitable for large-scale sensor networks with complex shapes and a non-uniform nodal distribution. In contrast to current state-of-the-art connectivity-based localization methods, the proposed algorithm is highly scalable with linear computation and communication costs with respect to the size of the network; and fully distributed where each node only needs the information of its neighbors without cumbersome partitioning and merging process. The algorithm is theoretically guaranteed and numerically stable. Moreover, the algorithm can be readily extended to the localization of networks with a one-hop transmission range distance measurement, and the propagation of …

Proposed Legislation Seeks To Stimulate Investment In Coastal Resiliency, Jon Cawley

News Items

No abstract provided.

Trim Tuning Of Sps-Series Dqw Crab Cavity Prototypes, S. Verdú-Andrés, J. Skaritka, Q. Wu, A. Ratti, S. Baurac, C. H. Boulware, T. Grimm, J. Yancey, W. Clemens, E. A. Mcewen, H. Park

Physics Faculty Publications

The final steps in the manufacturing of a superconducting RF cavity involve careful tuning before the final welds to match the target frequency as fabrication tolerances may introduce some frequency deviations. The target frequency is chosen based on analysis of the shifts induced by remaining processing steps including acid etching and cool down. The baseline fabrication of a DQW crab cavity for the High Luminosity LHC (HL-LHC) envisages a first tuning before the cavity subassemblies are welded together. To produce a very accurate final result, subassemblies are trimmed to frequency in the last machining steps, using a clamped cavity assembly …

Fermi Questions, Question 1: Too Many Mosquitoes; Question 2: Tug Of War, Larry Weinstein

Physics Faculty Publications

A quiz concerning the number of mosquitoes required to drain a human of blood and the amount of rope-tension in a tug of war contest.

Electromagnetic Design Of A Superconducting Twin Axis Cavity, S. U. De Silva, H. Park, J. R. Delayen, F. Marhauser, A. Hutton

Physics Faculty Publications

The twin-axis cavity is a new kind of rf superconducting cavity that consists of two parallel beam pipes, which can accelerate or decelerate two spatially separated beams in the same cavity. This configuration is particularly effective for high-current beams with low-energy electrons that will be used for bunched beam cooling of high-energy protons or ions. The new cavity geometry was designed to create a uniform accelerating or decelerating fields for both beams by utilizing a TM₁₁₀ dipole mode. This paper presents the design rf optimization of a 1497 MHz twin-axis single-cell cavity, which is currently under fabrication.

Development Of A Superconducting Twin Axis Cavity, H. Park, F. Marhauser, A. Hutton, S. U. De Silva, J. R. Delayen

Physics Faculty Publications

Superconducting cavities with two separate accelerating axes have been proposed in the past for energy recovery linac applications. While the study showed the advantages of such cavity, the designs present serious fabrication challenges. Hence the proposed cavities have never been built. The new design, elliptical twin cavity, proposed by Jefferson Lab and optimized by Center for Accelerator Science at Old Dominion University, allows similar level of engineering and fabrication techniques of a typical elliptical cavity. This paper describes preliminary LOM and HOM spectrum, engineering and fabrication processes of the twin axis cavity.

Modeling Local Crabbing Dynamics In The Jleic Ion Collider Ring, Salvador Sosa Guitron, Vasiliy Morozov, Jean Delayen

Physics Faculty Publications

The Jefferson Lab Electron-Ion Collider (JLEIC) design considers a 50 mrad crossing angle at the Interaction Point. Without appropriate compensation, this could geometrically reduce the luminosity by an order of magnitude. A local crabbing scheme is implemented to avoid the luminosity loss: crab cavities are placed at both sides of the interaction region to restore a head-on collision scenario. In this contribution, we report on the implementation of a local crabbing scheme in the JLEIC ion ring. The effects of this correction scheme on the stability of proton bunches are analyzed using the particle tracking software elegant.

The Role Of Sulfur Dioxide In Stratospheric Aerosol Formation Evaluated By Using In Situ Measurements In The Tropical Lower Stratosphere, A. W. Rollins, T. D. Thornberry, L. A. Watts, P. Yu, K. H. Rosenlof, M. Mills, E. Baumann, F. R. Giorgetta, T. V. Bui, M. Höpfner, P. F. Bernath

Chemistry & Biochemistry Faculty Publications

Stratospheric aerosols (SAs) are a variable component of the Earth's albedo that may be intentionally enhanced in the future to offset greenhouse gases (geoengineering). The role of tropospheric-sourced sulfur dioxide (SO₂) in maintaining background SAs has been debated for decades without in situ measurements of SO₂ at the tropical tropopause to inform this issue. Here we clarify the role of SO₂ in maintaining SAs by using new in situ SO₂ measurements to evaluate climate models and satellite retrievals. We then use the observed tropical tropopause SO₂ mixing ratios to estimate the global flux of …

Fourier Transform Spectroscopy Of The A3Π–X3Σ− Transition Of Oh+, James N. Hodges, Peter F. Bernath

Chemistry & Biochemistry Faculty Publications

The OH⁺ ion is of critical importance to the chemistry in the interstellar medium and is a prerequisite for the generation of more complex chemical species. Submillimeter and ultraviolet observations rely on high quality laboratory spectra. Recent measurements of the fundamental vibrational band and previously unanalyzed Fourier transform spectra of the near-ultraviolet A³Π-X 3Σ^- electronic spectrum, acquired at the National Solar Observatory at Kitt Peak in 1989, provide an excellent opportunity to perform a global fit of the available data. These new optical data are approximately four times more precise as compared to the previous values. …

Wakefield Analysis Of Superconducting Rf-Dipole Cavities, Subashini De Silva, Jean Delayen

Physics Faculty Publications

RF-dipole crabbing cavities are being considered for a variety of crabbing applications. Some of the applications are the crabbing cavity systems for LHC High Luminosity Upgrade and the proposed Electron-Ion Collider for Jefferson Lab. The design requirements in the current applications require the cavities to incorporate complex damping schemes to suppress the higher order modes that may be excited by the high intensity proton or electron beams traversing through the cavities. The number of cavities required to achieve the desired high transverse voltage, and the complexity in the cavity geometries also contributes to the wakefields generated by beams. This paper …

What Are The Low-Q And Large-X Boundaries Of Collinear Qcd Factorization Theorems?, E. Moffat, W. Melnitchouk, T. C. Rogers, N. Sato

Physics Faculty Publications

Familiar factorized descriptions of classic QCD processes such as deeply inelastic scattering (DIS) apply in the limit of very large hard scales, much larger than nonperturbative mass scales and other nonperturbative physical properties like intrinsic transverse momentum. Since many interesting DIS studies occur at kinematic regions where the hard scale, Q ∼ 1-2 GeV, is not very much greater than the hadron masses involved, and the Bjorken scaling variable x_bj is large, x_bj ≳ 0.5, it is important to examine the boundaries of the most basic factorization assumptions and assess whether improved starting points are needed. Using an …

Aluminum Multicharged Ion Generation From Femtosecond Laser Plasma, Md. Haider A. Shaim, Frederick Guy Wilson, Hani E. Elsayed-Ali

Electrical & Computer Engineering Faculty Publications

Aluminum multicharged ion generation from femtosecond laser ablation is studied. A Ti:sapphire laser (wavelength 800 nm, pulse width ∼100 fs, and maximum laser fluence of 7.6 J/cm²) is used. Ion yield and energy distribution of each charge state are measured. A linear relationship between the ion charge state and the equivalent acceleration energy of the individual ion species is observed and is attributed to the presence of an electric field within the plasma-vacuum boundary that accelerates the ions. The ion energy distribution follows a shifted Coulomb-Boltzmann distribution. For Al¹⁺ and Al²⁺, the ion energy distributions …

Target And Double Spin Asymmetries Of Deeply Virtual Π0 Production With A Longitudinally Polarized Proton Target And Clas, A. Kim, H. Avakian, V. Burkert, K. Joo, W. Kim, K. P. Adhikari, Z. Akbar, S. Anefalos Pereira, R. A. Badui, M. Battaglieri, S. Bültmann, A. Klein, S E. Kuhn, Y. Prok, B. Torayev, L. B. Weinstein, J. Zhang

Physics Faculty Publications

The target and double spin asymmetries of the exclusive pseudoscalar channel e→p→→epπ⁰ were measured for the first time in the deep-inelastic regime using a longitudinally polarized 5.9 GeV electron beam and a longitudinally polarized proton target at Jefferson Lab with the CEBAF Large Acceptance Spectrometer (CLAS). The data were collected over a large kinematic phase space and divided into 110 four-dimensional bins of Q^2, x_B, −t and ϕ. Large values of asymmetry moments clearly indicate a substantial contribution to the polarized structure functions from transverse virtual photon amplitudes. The interpretation of experimental data in terms of …

Link Between Local Phenology And Climate Change, Blake Steiner, Tatyana Lobova

Virginias Collegiate Honors Council Conference

The SouthEast Virginia Phenology Project was initiated as collaboration between Norfolk Botanical Garden and Old Dominion University in 2010 to document phenology of seven native plants and potential effects of the climate change on their life cycle. The air temperature in Norfolk has increased on average by 0.02ºC per year since 1980. Four out of seven of taxonomically diverse plant species (Mayapple, Flowering Dogwood, Highbush Blueberry, and Common ButtonBush) exhibited significant sensitivity to warming temperatures. Of these four, only Common Buttonbush (Cephalanthus occidentalis) had shown significant phenophases shift. Specifically, first flowering and first fruiting dates had shifted 2.7 …