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Articles 631 - 660 of 3797

Full-Text Articles in Physical Sciences and Mathematics

Nonlinear Multigrid Based On Local Spectral Coarsening For Heterogeneous Diffusion Problems, Chak Shing Lee, Francois Hamon, Nicola Castelletto, Panayot S. Vassilevski, Joshua A. White Dec 2020

Nonlinear Multigrid Based On Local Spectral Coarsening For Heterogeneous Diffusion Problems, Chak Shing Lee, Francois Hamon, Nicola Castelletto, Panayot S. Vassilevski, Joshua A. White

Mathematics and Statistics Faculty Publications and Presentations

This work develops a nonlinear multigrid method for diffusion problems discretized by cell-centered finite volume methods on general unstructured grids. The multigrid hierarchy is constructed algebraically using aggregation of degrees of freedom and spectral decomposition of reference linear operators associated with the aggregates. For rapid convergence, it is important that the resulting coarse spaces have good approximation properties. In our approach, the approximation quality can be directly improved by including more spectral degrees of freedom in the coarsening process. Further, by exploiting local coarsening and a piecewise-constant approximation when evaluating the nonlinear component, the coarse level problems are assembled and …


Microplastics In Pacific Northwest Bivalves: Ecological Prevalence, Harvester-Consumer Exposure, And Aquarium Exhibit Outcomes, Britta Rahel Baechler Nov 2020

Microplastics In Pacific Northwest Bivalves: Ecological Prevalence, Harvester-Consumer Exposure, And Aquarium Exhibit Outcomes, Britta Rahel Baechler

Dissertations and Theses

Up to 23 million metric tons of mismanaged plastics enter the global ocean annually. Microplastics (MPs;<5mm) degrading. MPs leak into the environment and now pervade every corner of the earth, with implications for animal, plant, ecosystem and human health. It is important to understand localized environmental MP prevalence, distribution and organismal uptake in order to determine the extent of MP pollution, and ultimately unlock solution sets to reduce transmission of MPs into the natural world. In Chapter 2, I quantified MP types, concentrations, anatomical burdens, geographic distribution, and temporal differences in Pacific oysters (Crassostrea gigas) and Pacific razor clams (Siliqua patula) from 15 coastal sites in Oregon. Both of these species are integral to culture, economy, gastronomy and food security along the United States West Coast. In Chapter 3, I quantified MPs in Pacific razor clams collected from 8 Olympic Coast, Washington sites, administered questionnaires to recreational razor clammers and subsequently estimated annual MP exposure of those Olympic Coast razor clam harvester-consumers surveyed. In Chapter 4, I designed and installed an educational ocean plastic …


Aryne-Guided C-H Functionalization Of Benzenoid Rings Using Diaryliodonium Salts, Aleksandra Nilova Nov 2020

Aryne-Guided C-H Functionalization Of Benzenoid Rings Using Diaryliodonium Salts, Aleksandra Nilova

Dissertations and Theses

The benzenoid core is a frequent and irreplaceable component of biologically active molecules. Structure function relationship of these compounds has been broadly analyzed and presented in numerous literature reports. Herein, we augmented existing knowledge by a broad analysis of the benzenoid substitution patterns in small molecule active pharmaceutical ingredients approved by the FDA. Our findings reveal a strong correlation that the most represented substitution patterns are those achieved via SEAr. Despite the rapid development of methods to functionalize benzenoid rings, the lack of synthetic methodologies to access sterically and electronically unfavorable positions is highlighted. We sought to establish …


A Posteriori Error Estimates For Maxwell's Equations Using Auxiliary Subspace Techniques, Ahmed El Sakori Nov 2020

A Posteriori Error Estimates For Maxwell's Equations Using Auxiliary Subspace Techniques, Ahmed El Sakori

Dissertations and Theses

The aim of our work is to construct provably efficient and reliable error estimates of discretization error for Nédélec (edge) element discretizations of Maxwell's equations on tetrahedral meshes. Our general approach for estimating the discretization error is to compute an approximate error function by solving an associated problem in an auxiliary space that is chosen so that:

-Efficiency and reliability results for the computed error estimates can be established under reasonable and verifiable assumptions.

-The linear system used to compute the approximate error function has condition number bounded independently of the discretization parameter.

In many applications, it is some functional …


A Posteriori Error Estimates For Elliptic Eigenvalue Problems Using Auxiliary Subspace Techniques, Stefano Giani, Luka Grubišić, Harri Hakula, Jeffrey S. Ovall Nov 2020

A Posteriori Error Estimates For Elliptic Eigenvalue Problems Using Auxiliary Subspace Techniques, Stefano Giani, Luka Grubišić, Harri Hakula, Jeffrey S. Ovall

Mathematics and Statistics Faculty Publications and Presentations

We propose an a posteriori error estimator for high-order p- or hp-finite element discretizations of selfadjoint linear elliptic eigenvalue problems that is appropriate for estimating the error in the approximation of an eigenvalue cluster and the corresponding invariant subspace. The estimator is based on the computation of approximate error functions in a space that complements the one in which the approximate eigenvectors were computed. These error functions are used to construct estimates of collective measures of error, such as the Hausdorff distance between the true and approximate clusters of eigenvalues, and the subspace gap between the corresponding true and approximate …


Investigation Of Prussian Blue Analogues As Cathode Materials For Next Generation Batteries, Neal Walters Kuperman Nov 2020

Investigation Of Prussian Blue Analogues As Cathode Materials For Next Generation Batteries, Neal Walters Kuperman

Dissertations and Theses

Since the beginning of the industrial revolution, the average global temperature has risen about 1 °C due increases in anthropogenic greenhouse gases emitted into the atmosphere. Of all human produced greenhouse gases, carbon dioxide is the most prevalent, with the production of electricity from fossil fuels being the major contributor.

Solar and wind power are promising net zero emission energy sources but only accounted for ~5% of global electricity generation in 2016. The most significant hurdle hindering their widespread adoption is the intermittent nature of the electricity generation. To overcome this limitation, significant resources need to be put into the …


The Gauge Principle From The Schrodinger-Born Wave Mechanics, P. T. Leung Nov 2020

The Gauge Principle From The Schrodinger-Born Wave Mechanics, P. T. Leung

Physics Faculty Publications and Presentations

We propose an elementary way of introducing the gauge principle to beginners with a background in only mechanics, electromagnetism, and quantum mechanics. This evolves from an apparent conflict in the Schrodinger-Born formulation of wave mechanics, and does not have to resort to advanced concepts like covariant derivative and minimal coupling. With such an approach, one would have appreciated how interactions can be dictated from consideration of internal symmetry of a physical system, which serves as a principle underlying the foundation of almost all modern physics. In addition, the gauge principle also serves as a resource providing consistency between the Born …


Nicotine In Tobacco Product Aerosols: 'It's Deja Vu All Over Again', Anna K. Duell, James F. Pankow, David H. Peyton Nov 2020

Nicotine In Tobacco Product Aerosols: 'It's Deja Vu All Over Again', Anna K. Duell, James F. Pankow, David H. Peyton

Chemistry Faculty Publications and Presentations

Introduction: The distribution of nicotine among its free-base (fb) and protonated forms in aerosolised nicotine affects inhalability. It has been manipulated in tobacco smoke and now in electronic cigarettes by the use of acids to de-freebase nicotine and form ‘nicotine salts’.

Methods: Measurements on electronic cigarette fluids (e-liquids) were carried out to determine (1) the fraction of nicotine in the free-base form (α fb) and (2) the levels of organic acid(s) and nicotine. Samples included JUUL ‘pods’, ‘look-a-like/knock-off’ pods and some bottled ‘nicotine salt’ and ‘non-salt’ e-liquids.

Results: α fb= 0.12 ±0.01 at 40°C (≈ 37°C) for 10 JUUL products, …


Extending The Functional Subnetwork Approach To A Generalized Linear Integrate-And-Fire Neuron Model, Nicholas Szczecinski, Roger Quinn, Alexander J. Hunt Nov 2020

Extending The Functional Subnetwork Approach To A Generalized Linear Integrate-And-Fire Neuron Model, Nicholas Szczecinski, Roger Quinn, Alexander J. Hunt

Mechanical and Materials Engineering Faculty Publications and Presentations

Engineering neural networks to perform specific tasks often represents a monumental challenge in determining network architecture and parameter values. In this work, we extend our previously-developed method for tuning networks of non-spiking neurons, the “Functional subnetwork approach” (FSA), to the tuning of networks composed of spiking neurons. This extension enables the direct assembly and tuning of networks of spiking neurons and synapses based on the network’s intended function, without the use of global optimization ormachine learning. To extend the FSA, we show that the dynamics of a generalized linear integrate and fire (GLIF) neuronmodel have fundamental similarities to those of …


The Cycle Structure Of Unicritical Polynomials, Andrew Bridy, Derek Garton Nov 2020

The Cycle Structure Of Unicritical Polynomials, Andrew Bridy, Derek Garton

Mathematics and Statistics Faculty Publications and Presentations

A polynomial with integer coefficients yields a family of dynamical systems indexed by primes as follows: for any prime p" role="presentation" style="box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-variant: inherit; font-stretch: inherit; line-height: normal; font-family: inherit; vertical-align: baseline; display: inline; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; position: relative;">pp⁠, reduce its coefficients mod p" role="presentation" style="box-sizing: border-box; margin: 0px; padding: 0px; border: 0px; font-variant: inherit; font-stretch: inherit; line-height: normal; font-family: inherit; vertical-align: baseline; display: inline; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; …


Determinants Of Green Purchase Intentions Of Saudi Consumers, Amani Mohammed Kaadoor Oct 2020

Determinants Of Green Purchase Intentions Of Saudi Consumers, Amani Mohammed Kaadoor

Dissertations and Theses

Much of the research on how and why consumers engage in pro-environmental consumption has occurred in the wealthy countries of the West, where green markets are increasingly well established. Research in other economic and cultural context is sparse and points to large regional differences that cause some researchers to call key theoretical foundations, such as the Theory of Planned Behavior, into question. In response, this study investigates the factors that predict green purchase intention for food and personal care products in Saudi Arabia, a wealthy country with a rapidly growing population, severe environmental challenges, and a nascent green consumer market …


Exploring The Potential Of Sparse Coding For Machine Learning, Sheng Yang Lundquist Oct 2020

Exploring The Potential Of Sparse Coding For Machine Learning, Sheng Yang Lundquist

Dissertations and Theses

While deep learning has proven to be successful for various tasks in the field of computer vision, there are several limitations of deep-learning models when compared to human performance. Specifically, human vision is largely robust to noise and distortions, whereas deep learning performance tends to be brittle to modifications of test images, including being susceptible to adversarial examples. Additionally, deep-learning methods typically require very large collections of training examples for good performance on a task, whereas humans can learn to perform the same task with a much smaller number of training examples.

In this dissertation, I investigate whether the use …


Newton Polygons Of Hecke Operators, Liubomir Chiriac, Andrei Jorza Oct 2020

Newton Polygons Of Hecke Operators, Liubomir Chiriac, Andrei Jorza

Mathematics and Statistics Faculty Publications and Presentations

In this computational paper we verify a truncated version of the Buzzard–Calegari conjecture on the Newton polygon of the Hecke operator T2 for all large enough weights. We first develop a formula for computing p-adic valuations of exponential sums, which we then implement to compute 2-adic valuations of traces of Hecke operators acting on spaces of cusp forms. Finally, we verify that if Newton polygon of the Buzzard–Calegari polynomial has a vertex at n≤15, then it agrees with the Newton polygon of T2 up to n.


Approximate Computing With Emerging Devices, Richard Atherton Oct 2020

Approximate Computing With Emerging Devices, Richard Atherton

Undergraduate Research & Mentoring Program

Approximate computation is a new trend that explores and harnesses trade-offs between the precision and energy/power consumption of computing systems. In this project a feed-forward neural network was designed as well as several reservoir networks using different network topologies to compare the accuracy and resilience of the network against the computational complexity required.


Trail Impact Monitoring In Forest Park, James Mitchell Oct 2020

Trail Impact Monitoring In Forest Park, James Mitchell

Environmental Science and Management Professional Master's Project Reports

Forest Park is an appropriately named 5,200 acre natural area located in northwest Portland, Oregon. A recent study estimated park usage near half a million annual visits and found "trails" to be the park’s most highly valued feature. Unfortunately, many trails were not designed for such traffic as evidenced by slipping hazards, erosion and other ecological impacts. In response to these observations, I partnered with Portland Parks & Recreation to conduct an objective trail impact assessment prescribed by the Forest Park Natural Resource Management Plan. I modified methods from past studies to expand on a recently completed trail condition class …


Genetically Encoded Phase Contrast Agents For Digital Holographic Microscopy, Arash Farhadi, Manuel Bedrossian, Justin Lee, Gabrielle H. Ho, Mikhail G. Shapiro, Jay Nadeau Oct 2020

Genetically Encoded Phase Contrast Agents For Digital Holographic Microscopy, Arash Farhadi, Manuel Bedrossian, Justin Lee, Gabrielle H. Ho, Mikhail G. Shapiro, Jay Nadeau

Physics Faculty Publications and Presentations

Quantitative phase imaging and digital holographic microscopy have shown great promise for visualizing the motion, structure and physiology of microorganisms and mammalian cells in three dimensions. However, these imaging techniques currently lack molecular contrast agents analogous to the fluorescent dyes and proteins that have revolutionized fluorescence microscopy. Here we introduce the first genetically encodable phase contrast agents based on gas vesicles. The relatively low index of refraction of the air-filled core of gas vesicles results in optical phase advancement relative to aqueous media, making them a “positive” phase contrast agent easily distinguished from organelles, dyes, or microminerals. We demonstrate this …


Convex Analysis Of Minimal Time And Signed Minimal Time Functions, D. V. Cuong, B. S. Mordukhovich, Mau Nam Nguyen, M. L. Wells Oct 2020

Convex Analysis Of Minimal Time And Signed Minimal Time Functions, D. V. Cuong, B. S. Mordukhovich, Mau Nam Nguyen, M. L. Wells

Mathematics and Statistics Faculty Publications and Presentations

In this paper we first consider the class of minimal time functions in the general setting of locally convex topological vector (LCTV) spaces. The results obtained in this framework are based on a novel notion of closedness of target sets with respect to constant dynamics. Then we introduce and investigate a new class of signed minimal time functions, which are generalizations of the signed distance functions. Subdifferential formulas for the signed minimal time and distance functions are obtained under the convexity assumptions on the given data.


Interests And Priorities In Sockeye Salmon Management: How Are Policies Enacted And Interpreted On Three Alaskan Rivers?, Jake P. Palazzi Oct 2020

Interests And Priorities In Sockeye Salmon Management: How Are Policies Enacted And Interpreted On Three Alaskan Rivers?, Jake P. Palazzi

University Honors Theses

The large export abundance of Alaskan salmon is well documented, and many studies have been performed to assess the economic and environmental viability of the industry and its management. Less research has been done to characterize how state intentions regarding fisheries allocation are conceived of by management or perceived by vulnerable groups in the user pool. This study seeks to qualitatively characterize the disconnect between state and Native Alaskan perceptions of management effectiveness, public interest, and Native Alaskan involvement using interviews. Results showed that Native Alaskan and state manager respondents had very different perceptions of management effectiveness and equity. When …


Do Fungal Symbionts Of Salt Marsh Plants Affect Interspecies Competition?, Vanessa Robertson-Rojas Sep 2020

Do Fungal Symbionts Of Salt Marsh Plants Affect Interspecies Competition?, Vanessa Robertson-Rojas

Dissertations and Theses

The effects of arbuscular mycorrhizal fungi (AMF) as salt marsh plant symbionts may have significant effects on landscape scale distribution patterns and plant-related ecosystem functions that are important to estuarine habitats. This work investigates the effects AMF have on Phalaris arundinacea, Deschampsia cespitosa, and Juncus balticus when grown in a common garden experiment. Plants were grown with and without AMF inoculation in both polyculture and monoculture communities and examined for a variety of response variables that represent different competition strategies. Factorial ANOVA analysis revealed a significant three-way interaction among fungal treatment type, community type, and species for …


Indoor Air Quality Impacts Of A Woodstove Exchange Program In Washington County, Oregon, Matthew Forrest Survilo Sep 2020

Indoor Air Quality Impacts Of A Woodstove Exchange Program In Washington County, Oregon, Matthew Forrest Survilo

Dissertations and Theses

More than six million people in the United States use wood stoves as their primary heat source. Wood stoves emit air pollutants that may impact health, e.g., wood combustion products are associated with premature death and aggravation of pulmonary and cardiovascular conditions. There are few studies investigating the efficacy of wood stove exchange programs (WSEPs) as a method to improve indoor air quality (IAQ). In partnership with Washington County Department of Health and Human Services we conducted an air quality study to measure the impact of a WSEP on indoor and neighborhood levels of wood combustion products. Twenty households engaged …


Waste Management In The Global South: An Inquiry On The Patterns Of Plastic And Waste Material Flows In Colombo, Sri Lanka, Katie Ann Conlon Sep 2020

Waste Management In The Global South: An Inquiry On The Patterns Of Plastic And Waste Material Flows In Colombo, Sri Lanka, Katie Ann Conlon

Dissertations and Theses

Global plastic production continues to increase at an exponential pace, and global waste projections show waste generation rising by 70% by 2050. Plastic waste connects to all social processes, especially within the context of urbanization and development; urban planning and land management; GHG emissions; labor; social equity; public health; rural-to-urban migration; increasing population; increasing consumption; climate change; etc. The focus of this dissertation is an analysis of waste management practices in Sri Lanka using a grounded theory based methodology, with a goal to better understand the social and ecological impacts of plastic waste in Sri Lanka. This research fills a …


Forest Density Intensifies The Importance Of Snowpack To Growth In Water-Limited Pine Forests, Kelly E. Gleason, John B. Bradford, Anthony W. D'Amato, Shawn Fraver, Brian J. Palik, Michael A. Battaglia Sep 2020

Forest Density Intensifies The Importance Of Snowpack To Growth In Water-Limited Pine Forests, Kelly E. Gleason, John B. Bradford, Anthony W. D'Amato, Shawn Fraver, Brian J. Palik, Michael A. Battaglia

Environmental Science and Management Faculty Publications and Presentations

Warming climate and resulting declines in seasonal snowpack have been associated with drought stress and tree mortality in seasonally snow‐covered watersheds worldwide. Meanwhile, increasing forest density has further exacerbated drought stress due to intensified tree–tree competition. Using a uniquely detailed data set of population‐level forest growth (n = 2,495 sampled trees), we examined how inter‐annual variability in growth relates to snow volume across a range of forest densities (e.g., competitive environments) in sites spanning a broad aridity gradient across the United States. Forest growth was positively related to snowpack in water‐limited forests located at low latitude, and this relationship was …


Investigation Of Magnetism In Transition Metal Chalcogenide Thin Films, Michael Adventure Hopkins Sep 2020

Investigation Of Magnetism In Transition Metal Chalcogenide Thin Films, Michael Adventure Hopkins

Dissertations and Theses

Layered two dimensional films have been a topic of interest in the materials science community driven by the intriguing properties demonstrated in graphene. Tunable layer dependent electrical and magnetic properties have been shown in these materials and the ability to grow in the hexagonal phase provides opportunities to grow isostructural stacked heterostructures. In this investigation, cobalt selenide (CoSe) and nickel selenide (NiSe) were grown in the hexagonal phase, which consist of central metal atoms that are natively ferromagnetic in bulk, hence providing the potential for interesting magnetic phases in thin film arrangements as well. These structures may play a role …


A Seasonal Study Of Ecoroof Metal And Nutrient Dynamics And Associated Drivers In An Ecoroof On A Commercial Building In North Portland Oregon, Alex Vijay Bans Sep 2020

A Seasonal Study Of Ecoroof Metal And Nutrient Dynamics And Associated Drivers In An Ecoroof On A Commercial Building In North Portland Oregon, Alex Vijay Bans

Dissertations and Theses

Green stormwater infrastructure (GSI), specifically ecoroofs, is increasingly seen as an effective stormwater management tool in urban planning strategies. However, the literature suggests that ecoroofs can be sources of certain metals and nutrients. The goal of our study was to address two research questions: 1) How does ecoroof runoff compare to conventional roof runoff chemically: do ecoroofs retain certain chemicals and leach others? and 2) what are the roof characteristics and environmental variables that affect runoff quality? For 10 months, runoff events from an ecoroof were compared to those of a conventional roof; water samples were collected with autosamplers, and …


Late-Holocene Shoreline Responses To Competing Shelf, Bay, And Beach Accommodation Spaces Under Conditions Of Relative Sea Level Change, And The Potential For Future Catastrophic Beach Retreat In The Columbia River Littoral Cell, Washington And Oregon, Usa, Curt D. Peterson, Tamara C. Linde, Sandy Vanderburgh Sep 2020

Late-Holocene Shoreline Responses To Competing Shelf, Bay, And Beach Accommodation Spaces Under Conditions Of Relative Sea Level Change, And The Potential For Future Catastrophic Beach Retreat In The Columbia River Littoral Cell, Washington And Oregon, Usa, Curt D. Peterson, Tamara C. Linde, Sandy Vanderburgh

Geology Faculty Publications and Presentations

The Columbia River Littoral Cell (CRLC) (160 km in length) provides opportunities to compare competing accommodation space relations under different conditions of relative sea level change. The CRLC system includes abundant littoral sand supply from the large Columbia River, late-Holocene prograded beach plains and barrier spits (0.5–5 km in width), two large marine-dominated estuaries (Willapa Bay and Grays Harbor), and a high-wave-energy inner-shelf. Littoral sand accumulation rates in prograded beach plains and barrier deposits are based on paleo-shoreline positions that are dated by great-earthquake catastrophic beach retreat scarps (n = 10) from 0.3 to 5.0 ka. The retreat scarp timelines …


Reducing A Class Of Two-Dimensional Integrals To One-Dimension With An Application To Gaussian Transforms, Jack C. Straton Sep 2020

Reducing A Class Of Two-Dimensional Integrals To One-Dimension With An Application To Gaussian Transforms, Jack C. Straton

Physics Faculty Publications and Presentations

Quantum theory is awash in multidimensional integrals that contain exponentials in the integration variables, their inverses, and inverse polynomials of those variables. The present paper introduces a means to reduce pairs of such integrals to one dimension when the integrand contains powers multiplied by an arbitrary function of xy/ (x + y) multiplying various combinations of exponentials. In some cases these exponentials arise directly from transition-amplitudes involving products of plane waves, hydrogenic wave functions, and Yukawa and/or Coulomb potentials. In other cases these exponentials arise from Gaussian transforms of such functions.


Electromagnetic Reciprocity In The Presence Of Topological Insulators, Huai-Yi Xie, P. T. Leung Sep 2020

Electromagnetic Reciprocity In The Presence Of Topological Insulators, Huai-Yi Xie, P. T. Leung

Physics Faculty Publications and Presentations

Electromagnetic reciprocity is studied in the presence of topological insulators (TI) with application of axion electrodynamics for harmonic electromagnetic fields. The corresponding generalized Lorentz and Feld-Tai type lemmas are derived in terms of the axion coupling parameter, and their correlation to the conditional symmetry in source-observer coordinates for the various Green dyadics is established subjected to different types of boundary conditions. Possible application of the results to the probing of the topological magneto-electric effects from TI is discussed.


Rainfall Triggers More Deep-Seated Landslides Than Cascadia Earthquakes In The Oregon Coast Range, Usa, Sean R. Lahusen, Alison R. Duvall, Adam M. Booth, A. Grant, Ben A. Mishkin, David R. Montgomery, Will Struble, Joshua J. Roering, J. Wartman Sep 2020

Rainfall Triggers More Deep-Seated Landslides Than Cascadia Earthquakes In The Oregon Coast Range, Usa, Sean R. Lahusen, Alison R. Duvall, Adam M. Booth, A. Grant, Ben A. Mishkin, David R. Montgomery, Will Struble, Joshua J. Roering, J. Wartman

Geology Faculty Publications and Presentations

The coastal Pacific Northwest USA hosts thousands of deep-seated landslides. Historic landslides have primarily been triggered by rainfall, but the region is also prone to large earthquakes on the 1100-km-long Cascadia Subduction Zone megathrust. Little is known about the number of landslides triggered by these earthquakes because the last magnitude 9 rupture occurred in 1700 CE. Here, we map 9938 deep-seated bedrock landslides in the Oregon Coast Range and use surface roughness dating to estimate that past earthquakes triggered fewer than half of the landslides in the past 1000 years. We find landslide frequency increases with mean annual precipitation but …


Designing A More Effective Mri Contrast Agent: Investigation Into Various Functionalization Strategies For Targeted Imaging, Lauren Nicole Rust Aug 2020

Designing A More Effective Mri Contrast Agent: Investigation Into Various Functionalization Strategies For Targeted Imaging, Lauren Nicole Rust

Dissertations and Theses

Magnetic resonance imaging (MRI) is a medical imaging technique that provides high-resolution images used for diagnostic medicine while maintaining a superior safety profile compared to other radiative techniques. The administration of gadolinium-based contrast agents (GBCAs) improves the diagnostic power of MRI and have been used clinically for over three decades. Although GBCAs are effective at improving the contrast in the image, their detection limits are high and require a large dose to generate an observable effect. This high dose is the consequence of the current available designs of clinical GBCAs; their structures are not tuned to generate optimal efficacy. Efficacy …


Distribution, Geochronology, And Petrogenesis Of The Picture Gorge Basalt With Special Focus On Petrological Relationships To The Main Columbia River Basalt Group, Emily Bogdan Cahoon Aug 2020

Distribution, Geochronology, And Petrogenesis Of The Picture Gorge Basalt With Special Focus On Petrological Relationships To The Main Columbia River Basalt Group, Emily Bogdan Cahoon

Dissertations and Theses

The Columbia River Basalt Group (CRBG) is the youngest and volumetrically smallest continental flood basalt exposed across the Pacific Northwest, USA. Similar to other large igneous provinces, the majority of material erupted during the initial 1 million years of activity, these lavas are subdivided into four main-phase units. The Picture Gorge Basalt (PGB) is the only main-phase unit of the CRBG whose age is not precisely known and understanding of PGB petrogenesis is largely based on a limited number of samples when compared with other main-phase units. It is suggested that a time gap of over 0.5 myr existed between …