Physical Sciences and Mathematics Commons^™

Mitigating The Challenges Of Grazing Lush, Spring Forages, W. Travis Meteer

Kentucky Grazing Conference

During the winter season most cattle are supplemented with dry forages, grains, and co-products. This ration is balanced and delivered to cattle. Then spring comes along and cattle are put out to grass. While green grass solves a lot of problems associated with winter feeding (manure, pen maintenance, calf health, and labor demands), it can pose nutritional challenges. Lush, spring forage has three major challenges when it comes to meeting cattle nutrition requirements.

Seedhead Suppression In Tall Fescue With Chaparral Herbicide, E. S. Flynn, P. B. Burch

Kentucky Grazing Conference

Tall Fescue (Lolium arundinaceum (Schreb.)) is cool-season perennial grass found in pastures throughout the Eastern US, most commonly in the transition zone. It’s tolerance to extreme temperatures, drought, poor soil fertility, heavy grazing, and pests have made it a reliable forage base for livestock pastures. Released in 1943, ‘KY-31’ tall fescue was quickly adopted by cattle producers and now inhabits an estimated 40 million acres in the US.

Soon after its adoption, cattle producers began to notice a reduction in animal performance and signs that animals were heat stressed following tall fescue consumption. These symptoms were an indication of an …

Fescue Tolerance Testing, Monty Kerley

Kentucky Grazing Conference

Fescue toxicosis is characterized by clinical symptoms such as vasoconstriction, immunosuppression, and poor thermoregulation. Fescue toxins bind to membrane receptors of cells that control constriction of blood through capillaries responsible for heat dissipation. When cattle consume toxic tall fescue, they lose ability to move blood to their skin where heat can be lost to the environment. As they lose this ability they become more prone to heat stress. In the winter, this lack of blood flow leads to other clinical symptoms, such as fescue foot and loss of tail switch, that occur from restricted blood flow.

Research Update: Beef Cattle Management Considerations For Grazing Tall Fescue, Frank Ireland

Kentucky Grazing Conference

It has been reported that 8 million beef cattle graze an estimated 35 million acres of endophyte-infected tall fescue in the United States with the majority of tall fescue being produced in the Midwest and southeastern regions of the United States. In the presence of the endophytic fungus, ergot alkaloids are present that when consumed by beef cattle results in decreased animal performance as measured in reduced weight gains, lower body condition scores, decreased conception rates, rough hair coats and the inability to regulate body temperatures. It has been estimated that this loss in animal performance accounts for a $600 …

In Defense Of Soil Health, Allen R. Williams

Kentucky Grazing Conference

Soil health is a hot topic today in sustainable agriculture circles and is even becoming more popular in conventional agriculture. However, the term is often thrown around loosely, and sometimes the meaning gets muddled.

Foreword And Conference Information [2017], Matt Bunger

Kentucky Grazing Conference

This is the front matter of the proceedings.

Relaxation Of Charge In Monolayer Graphene: Fast Nonlinear Diffusion Versus Coulomb Effects, Eugene B. Kolomeisky, Joseph P. Straley

Physics and Astronomy Faculty Publications

Pristine monolayer graphene exhibits very poor screening because the density of states vanishes at the Dirac point. As a result, charge relaxation is controlled by the effects of zero-point motion (rather than by the Coulomb interaction) over a wide range of parameters. Combined with the fact that graphene possesses finite intrinsic conductivity, this leads to a regime of relaxation described by a nonlinear diffusion equation with a diffusion coefficient that diverges at zero charge density. Some consequences of this fast diffusion are self-similar superdiffusive regimes of relaxation, the development of a charge depleted region at the interface between electron- and …

Removable Singularities In C*-Algebras Of Real Rank Zero, Lawrence A. Harris

Mathematics Faculty Publications

Let 𝕬 be a C*-algebra with identity and real rank zero. Suppose a complex- valued function is holomorphic and bounded on the intersection of the open unit ball of 𝕬 and the identity component of the set of invertible elements of 𝕬. We give a short transparent proof that the function has a holomorphic extension to the entire open unit ball of 𝕬. The author previously deduced this from a more general fact about Banach algebras.

Doping Evolution Of Magnetic Order And Magnetic Excitations In (Sr1-XLaX)3Ir2O7, Xingye Lu, D. E. Mcnally, M. Moretti Sala, Jsaminka Terzic, M. H. Upton, D. Casa, G. Ingold, Gang Cao, T. Schmitt

Physics and Astronomy Faculty Publications

We use resonant elastic and inelastic x-ray scattering at the Ir-L₃ edge to study the doping-dependent magnetic order, magnetic excitations, and spin-orbit excitons in the electron-doped bilayer iridate (Sr_1−xLa_x)₃Ir₂O₇ (0 ≤ x ≤ 0.065). With increasing doping x, the three-dimensional long range antiferromagnetic order is gradually suppressed and evolves into a three-dimensional short range order across the insulator-to-metal transition from x = 0 to 0.05, followed by a transition to two-dimensional short range order between x = 0.05 and 0.065. Because of the interactions between the J …

Longitudinal Measurement And Hierarchical Classification Framework For The Prediction Of Alzheimer's Disease, Meiyan Huang, Wei Yang, Qianjin Feng, Wufan Chen, Michael Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack Jr., William Jagust, John Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew Saykin, John Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph Quinn, Lisa Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan Spann, James Brewer, Helen Vanderswag, Adam Fleisher, Charles D. Smith, Greg A. Jicha, Peter A. Hardy, Partha Sinha, Elizabeth Oates, Gary Conrad

Neurology Faculty Publications

Accurate prediction of Alzheimer’s disease (AD) is important for the early diagnosis and treatment of this condition. Mild cognitive impairment (MCI) is an early stage of AD. Therefore, patients with MCI who are at high risk of fully developing AD should be identified to accurately predict AD. However, the relationship between brain images and AD is difficult to construct because of the complex characteristics of neuroimaging data. To address this problem, we present a longitudinal measurement of MCI brain images and a hierarchical classification method for AD prediction. Longitudinal images obtained from individuals with MCI were investigated to acquire important …

Correlation Of Positron Emission Tomography/Computed Tomography Scan With Smoking, Tumor Size, Stage And Differentiation In Head And Neck Cancer Patients, Jordan L. Pleitz, Partha Sinha, Emily V. Dressler, Rony K. Aouad

Otolaryngology--Head & Neck Surgery Faculty Publications

The goal of this study was to identify associations between positron emission tomography/computed tomography (PET/CT) maximum standardized uptake value (SUVmax) in patients presenting with head and neck squamous cell carcinoma (SCC) with tumor site, size, histologic differentiation, smoking, and diabetes. Charts of patients with oropharyngeal and laryngeal SCC who underwent ¹⁸F-fluorodeoxyglucose PET/CT scans were reviewed between May 2007 and August 2013. Statistical analyses included modeling log-transformed SUVmax values by tumor site, size, histologic differentiation, smoking status, and diabetes using unadjusted linear regressions. Differences were considered statistically significant for P< 0.05. A total of 111 patients (54 with oropharynx and 57 with larynx cancers) were included, 83 men and 28 women with an average age of 57.5 years old. There was a significantly higher pack-year smoking history (P = 0.005) in the larynx cancer group. While tumor …

Design And Performance Of Sipm-Based Readout Of Pbf2 Crystals For High-Rate, Precision Timing Applications, J. Kaspar, A. T. Fienberg, D. W. Hertzog, M. A. Huehn, P. Kammel, K. S. Khaw, D. A. Peterson, M. W. Smith, T. D. Vanwechel, A. Chapelain, L. K. Gibbons, D. A. Sweigart, C. Ferrari, A. Fioretti, C. Gabbanini, G. Venanzoni, M. Iacovacci, S. Mastroianni, K. Giovanetti, W. Gohn, Tim Gorringe, D. Pocanic

Physics and Astronomy Faculty Publications

We have developed a custom amplifier board coupled to a large-format 16-channel Hamamatsu silicon photomultiplier device for use as the light sensor for the electromagnetic calorimeters in the Muon g - 2 experiment at Fermilab. The calorimeter absorber is an array of lead-fluoride crystals, which produces short-duration Cherenkov light. The detector sits in the high magnetic field of the muon storage ring. The SiPMs selected, and their accompanying custom electronics, must preserve the short pulse shape, have high quantum efficiency, be non-magnetic, exhibit gain stability under varying rate conditions, and cover a fairly large fraction of the crystal exit surface …

Organelle_Pba, A Pipeline For Assembling Chloroplast And Mitochondrial Genomes From Pacbio Dna Sequencing Data, Aboozar Soorni, David Haak, David Zaitlin, Aureliano Bombarely

Kentucky Tobacco Research and Development Center Faculty Publications

Background: The development of long-read sequencing technologies, such as single-molecule real-time (SMRT) sequencing by PacBio, has produced a revolution in the sequencing of small genomes. Sequencing organelle genomes using PacBio long-read data is a cost effective, straightforward approach. Nevertheless, the availability of simple-to-use software to perform the assembly from raw reads is limited at present.

Results: We present Organelle-PBA, a Perl program designed specifically for the assembly of chloroplast and mitochondrial genomes. For chloroplast genomes, the program selects the chloroplast reads from a whole genome sequencing pool, maps the reads to a reference sequence from a closely related species, and …

Charge-Dependent Directed Flow In Cu + Au Collisions At √SNn = 200 Gev, L. Adamczyk, James K. Adkins, G. Agakishiev, M. M. Aggarwal, Z. Ahammed, I. Alekseev, D. M. Anderson, R. Aoyama, A. Aparin, D. Arkhipkin, E. C. Aschenauer, M. U. Ashraf, A. Attri, G. S. Averichev, X. Bai, V. Bairathi, R. Bellwied, A. Bhasin, A. K. Bhati, P. Bhattarai, J. Bielcik, J. Bielcikova, L. C. Bland, I. G. Bordyuzhin, J. Bouchet, J. D. Brandenburg, A. V. Brandin, I. Bunzarov, J. Butterworth, H. Caines, Renee H. Fatemi, Suvarna Ramachandran

Physics and Astronomy Faculty Publications

We present the first measurement of charge-dependent directed flow in Cu + Au collisions at √s_NN = 200  GeV. The results are presented as a function of the particle transverse momentum and pseudorapidity for different centralities. A finite difference between the directed flow of positive and negative charged particles is observed that qualitatively agrees with the expectations from the effects of the initial strong electric field between two colliding ions with different nuclear charges. The measured difference in directed flow is much smaller than that obtained from the parton-hadron-string-dynamics model, which suggests that most of the electric charges, …

Fourth-Generation Fan Assessment Numeration System (Fans) Design And Performance Specifications, Michael P. Sama, George B. Day, Laura M. Pepple, Richard S. Gates

Biosystems and Agricultural Engineering Faculty Publications

The Fan Assessment Numeration System (FANS) is a measurement device for generating ventilation fan performance curves. Three different-sized FANS currently exist for assessing ventilation fans commonly used in poultry and livestock housing systems. All FANS consist of an array of anemometers inside an aluminum shroud that traverse the inlet or outlet of a ventilation fan. The FANS design has been updated several times since its inception and is currently in its fourth-generation (G4). The current design iteration (FANS-G4) is reported in this article with an emphasis on the hardware and software control, data acquisition systems, and operational reliability. Six FANS-G4 …

Comparative Proteomic Analyses Of The Parietal Lobe From Rhesus Monkeys Fed A High-Fat/Sugar Diet With And Without Resveratrol Supplementation, Relative To A Healthy Diet: Insights Into The Roles Of Unhealthy Diets And Resveratrol On Function, Aaron M. Swomley, Judy C. Triplett, Jeriel T. Keeney, Govind Warrier, Kevin J. Pearson, Julie A. Mattison, Rafael De Cabo, Jian Cai, Jon B. Klein, D. Allan Butterfield

Chemistry Faculty Publications

A diet consisting of a high intake of saturated fat and refined sugars is characteristic of a Western-diet and has been shown to have a substantial negative effect on human health. Expression proteomics were used to investigate changes to the parietal lobe proteome of rhesus monkeys consuming either a high fat and sugar (HFS) diet, a HFS diet supplemented with resveratrol (HFS+RSV), or a healthy control diet for 2 years. Here we discuss the modifications in the levels of 12 specific proteins involved in various cellular systems including metabolism, neurotransmission, structural integrity, and general cellular signaling following a nutritional intervention. …

Effects Of Biochar Treatment Of Municipal Biosolids And Horse Manure On Quality Of Runoff From Fescue Plots, Rachel Williams, Dwayne R. Edwards

Biosystems and Agricultural Engineering Faculty Publications

Land-applied horse manure and municipal biosolids can increase nutrient and bacteria concentrations in runoff. Biochar has been demonstrated to have beneficial impacts on nutrient retention and runoff quality when used to treat other land-applied organic soil amendments (e.g., poultry manure). The objective of this study was to evaluate the effects of biochar addition to horse manure and municipal biosolids on runoff concentrations of nutrients and fecal coliforms. Biochar was added at 5% to 8% (wet basis) to horse manure and biosolids that were applied to 2.4 m x 6.1 m fescue plots followed by application of simulated rainfall (102 mm …

Automated Calibration Of Electrochemical Oxygen Sensors For Use In Compost Bedded Pack Barns, John T. Evans, Michael P. Sama, Joseph L. Taraba, George B. Day

Biosystems and Agricultural Engineering Faculty Publications

The objective of this study was to develop an automated calibration process for a galvanic cell type oxygen sensor. The manufacturer recommended a two-point calibration at room temperature; however, testing revealed that the response was not linear when both the temperature and oxygen concentrations varied. Thus, additional points were needed to generate a representative calibration equation and to reduce the sensor prediction interval. The calibration process needed to be capable of automatically recording sensor response (voltage) at an array of temperatures and oxygen concentrations. Calibration gases were used to precisely control the oxygen concentration inside a small manifold, and an …

Bis(N-Amidinohydrazones) And N-(Amidino)-N'-Aryl-Bishydrazones: New Classes Of Antibacterial/Antifungal Agents, Sanjib K. Shrestha, Liliia M. Kril, Keith D. Green, Stefan Kwiatkowski, Vitaliy M. Sviripa, Justin Robert Nickell, Linda Phyliss Dwoskin, David S. Watt, Sylvie Garneau-Tsodikova

Pharmaceutical Sciences Faculty Publications

The emergence of multidrug-resistant bacterial and fungal strains poses a threat to human health that requires the design and synthesis of new classes of antimicr obial agents. We evaluated bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones for their antibacterial and antifungal activities against panels of Gram-positive/Gram-negative bacteria as well as fungi. We investigated their potential to develop resistance against both bacteria and fungi by a multi-step, resistance-selection method, explored their potential to induce the production of reactive oxygen species, and assessed their toxicity. In summary, we found that these compounds exhibited broad-spectrum antibacterial and antifungal activities against most of …

Field Investigation Of An Active Landslide In Kentucky: A Framework To Correlate Electrical Data And Shear Strength, Matthew M. Crawford, L. Sebastian Bryson

Report of Investigations--KGS

Landslide hazard assessments are best accomplished by a multidisciplinary approach that connects geologic processes with geotechnical behavior. Tools to accomplish this in the field include geologic characterization, hydrologic monitoring, and geophysical surveys, and in the laboratory, soil-strength testing. Volumetric water content, soil-water potential (suction), local rainfall, and in situ electrical conductivity were measured at a shallow colluvial landslide in Kentucky. Surface electrical-resistivity surveys were also conducted to support interpretations of depth to failure, lithologic differences, and changes in moisture content over time. Correlations of hydrologic data with electrical measurements and shear strength indicate that observed changes in the degree of …

Ammonia And Carbon Dioxide Emissions Of Three Laying-Hen Housing Systems As Affected By Manure Accumulation Time, Timothy A. Shepherd, Hongwei Xin, John P. Stinn, Morgan D. Hayes, Yang Zhao, Hong Li

Biosystems and Agricultural Engineering Faculty Publications

Laying-hen housing design and management are the most significant factors affecting the generation and release of gaseous ammonia to the atmosphere. Transitioning the hen housing type from traditional high-rise (where manure is stored within the house for about one year) to modern manure-belt style (where manure is removed every 1 to 4 d and placed into long-term storage) has significantly improved in-barn air quality and reduced farm-level ammonia emissions. As a direct result of the advantages, 100% of new construction for U.S. egg production incorporates manure-belt systems that regularly remove manure from the houses. However, manure-belt system designs (e.g., active …

Assessment Of Potential Impacts To Surface And Subsurface Water Bodies Due To Longwall Mining, Christopher R. Newman, Zacharias Agioutantis, Gabriel Boede Jimenez Leon

Mining Engineering Faculty Publications

Ground movements due to longwall mining operations have the potential to damage the hydrological balance within as well as outside the mine permit area in the form of increased surface ponding and changes to hydrogeological properties. Recently, the Office of Surface Mining, Reclamation and Enforcement (OSMRE) in the USA, has completed a public comment period on a newly proposed rule for the protection of streams and groundwater from adverse impacts of surface and underground mining operations (80 FR 44435). With increased community and regulatory focus on mining operations and their potential to adversely affect streams and groundwater, now there is …

Zircon As A Proxy For "Taking The Temperature" Of Granites: An Example Using Zircon Thermometry Applied To Grenvillian Mid-Crustal Magmas In The Blue Ridge Province, Virginia, Samantha Rae Burk

Theses and Dissertations--Earth and Environmental Sciences

The Grenville orogeny was a protracted (~200 m.y.) series of “hot” magmatic- metamorphic events that contributed to the growth of the Laurentian margin in the late Mesoproterozoic. The granites contain remarkably high Zr content, lack xenocrysts, and become zircon saturated at high temperatures, which are all unusual for felsic magmas. The “hot Grenville granite” hypothesis is tested and use of high-Zr granitoids as potential zones of crustal magma generation through: U-Pb geochronology and cathodoluminescence imaging to assess inherited zircon components; quantitative modeling of zircon crystallization history using rhyolite-MELTS; and Ti-in-zircon thermometry. U-Pb zircon ages for two samples from the Virginia …

Effects Of Hydrologic Connectivity And Land Use On Floodplain Sediment Accumulation At The Savannah River Site, South Carolina, Jeremy E. Eddy

Theses and Dissertations--Earth and Environmental Sciences

Floodplains, and the sediment accumulating naturally on them, are important to maintain stream water quality and serve as sinks for organic and inorganic carbon. Newer theories contend that land use and hydrologic connectivity (water-mediated transport of matter, energy, and/or organisms within or between elements of the hydrologic cycle) play important roles in determining sediment accumulation on floodplains. This study hypothesizes that changes in hydrologic connectivity have a greater impact on floodplain sediment accumulation than changes in land use. Nine sediment cores from seven sub-basins were collected from the Savannah River Site (SRS), South Carolina, and processed for grain-size, radionuclide dating …

Constraining Boundaries And Extent Of The Charleston Uplift, Northeast New Madrid Seismic Zone, Using Shallow Seismic Reflection Methods, Clara Rose Rucker

Theses and Dissertations--Earth and Environmental Sciences

A recently identified 30 km by 7.2 km subsurface stratigraphic uplift, called the Charleston uplift, exhibits 36 m offset of Paleogene-Quaternary unconformity based on shallow borehole data. Two seismic soundings demonstrated relief in Paleozoic and Cretaceous reflectors across the northern boundary of the uplift, suggesting a structural origin rather than an erosional origin. This study collected and analyzed 18 additional shallow seismic soundings to confirm Paleozoic and Cretaceous offset across the boundaries of the uplift, to better constrain the surface trace of the uplift, and to examine potential extension into western Kentucky. One ground penetrating radar profile was taken in …

Neutron Decay Correlations In The Nab Experiment, L. J. Broussard, R. Alarcon, S. Baeßler, L. Barrón Palos, N. Birge, T. Bode, J. D. Bowman, T. Brunst, J. R. Calarco, J. Caylor, T. Chupp, V. Cianciolo, Christopher Crawford, G. W. Dodson, J. Dubois, W. Fan, W. Farrar, N. Fomin, E. Frlež, J. Fry, M. T. Gericke, F. Glück, G. L. Greene, R. K. Grzywacz, V. Gudkov, C. Hendrus, F. W. Hersman, T. Ito, H. Li, N. Macsai, Bradley R. Plaster, Aaron P. Sprow

Physics and Astronomy Faculty Publications

The Nab experiment will measure the correlation a between the momenta of the beta particle and antineutrino in neutron decay as well as the Fierz term b which distorts the beta spectrum.

Research At The University Of Kentucky Accelerator Laboratory, S. F. Hicks, Michael A. Kovash

Physics and Astronomy Faculty Publications

The Department of Physics and Astronomy at the University of Kentucky operates a 7-MV CN Van de Graaff accelerator that produces primary beams of protons, deuterons, and helium ions. An in-terminal pulsing and bunching system operates at 1.875 MHz and is capable of providing 1 ns beam bunches at an average current of several microamperes. Nearly all ongoing research programs involve secondary pulsed neutrons produced with gas cells containing deuterium or tritium, as well as with a variety of solid targets. Most experiments are performed at a target station positioned over a deep pit, so as to reduce the background …

Kentucky Stratigraphy, Stephen F. Greb

Map and Chart--KGS

No abstract provided.

A Predictive Probability Interim Design For Phase Ii Clinical Trials With Continuous Endpoints, Meng Liu

Theses and Dissertations--Epidemiology and Biostatistics

Phase II clinical trials aim to potentially screen out ineffective and identify effective therapies to move forward to randomized phase III trials. Single-arm studies remain the most utilized design in phase II oncology trials, especially in scenarios where a randomized design is simply not practical. Due to concerns regarding excessive toxicity or ineffective new treatment strategies, interim analyses are typically incorporated in the trial, and the choice of statistical methods mainly depends on the type of primary endpoints. For oncology trials, the most common primary objectives in phase II trials include tumor response rate (binary endpoint) and progression disease-free survival …

An Exploratory Statistical Method For Finding Interactions In A Large Dataset With An Application Toward Periodontal Diseases, Joshua Lambert

Theses and Dissertations--Epidemiology and Biostatistics

It is estimated that Periodontal Diseases effects up to 90% of the adult population. Given the complexity of the host environment, many factors contribute to expression of the disease. Age, Gender, Socioeconomic Status, Smoking Status, and Race/Ethnicity are all known risk factors, as well as a handful of known comorbidities. Certain vitamins and minerals have been shown to be protective for the disease, while some toxins and chemicals have been associated with an increased prevalence. The role of toxins, chemicals, vitamins, and minerals in relation to disease is believed to be complex and potentially modified by known risk factors. A …