Physical Sciences and Mathematics Commons^™

The In-Situ Removal Of Menthofuran From Peppermint Oil And Subsequent Reactions Of The Solid-Supported Adduct, Robert Joseph Justice Ii

Dissertations

Menthofuran is an aromatic heterocyclic compound found naturally in the essential oil of Mentha piperita L. or peppermint. Natural peppermint oil may contain between approximately 2 to 8% menthofuran.

Peppermint oil is a complex mixture of over 350 identified chemical compounds; market demands dictate the extent of processing the oil undergoes prior to being introduced into consumer goods. Menthofuran has long been known to readily autoxidize, either alone or within the peppermint oil matrix, leading to a discolored oil with negative organoleptic consequences that adversely affects its commercial viability. Therefore, a facile method for selective removal of menthofuran was developed …

Option Pricing And Stable Trading Strategies In The Presence Of Information Asymmetry, Anirban Dutta

Dissertations

Pricing derivatives is one of the central issues in mathematical finance. The seminal work of Black, Scholes and Merton has been the cornerstone of option pricing since their introduction in 1973. Their work influenced the pricing theory of other derivatives as well.

This derivative pricing theory has two primary shortcomings. Firstly, the theoretical pricing in such theories are not accompanied by a stable trading strategy. Secondly, they often assume that the market agents use a uniform model for the underlying instrument and that the market prices of the derivatives reveal all the information about the underlying instrument.

Theoreticians like Grossman …

Molecular Design And Patterning Of Biosurfaces On Poly(Tetrafluoroethylene) (Ptfe), Nattharika Aumsuwan

Dissertations

This dissertation describes the design, synthesis, and development of biocompatible poly(tetrafluoroethylene) (PTFE) surfaces that exhibit anti-microbial, anticoagulant, and dual functional surface properties. It consists of two parts: (1) design, synthesis, and analysis of antimicrobial and anti-coagulant PTFE surfaces, and (2) controllable micropatterning of anti-microbial and anti-coagulant species on the surface. PTFE was modified by Ar microwave plasma reactions in the presence of maleic anhydride, which upon hydrolysis creating COOH groups. These COOH primers were utilized as a platform for further surface reactions to attach polyethylene glycol (PEG) spacers, and penicillin (PEN) or ampicillin (AM) onto the PTFE surfaces. The use …

Nanomaterials From Biologically Active Molecules: Self-Assembly And Molecular Recognition, Min Yu

Dissertations

This dissertation describes the development of molecular assemblies and molecular recognition of phospholipids (PLs) that exhibit potential applications in emerging nanotechnologies. It consists of two parts: (1) structural features of PLs responsible for recognition of synthetic copolymers, and (2) design, synthesis and analysis of magnetic nanotubes obtained from PLs with a common theme of colloidal synthesis served as a platform for film formation and nano-assemblies of nanotubes. Poly(methyl methacrylate/n-butyl acrylate) (p-MMA/nBA) colloidal particles that were stabilized by 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC) PLs were synthesized, and upon the particle coalescence, PL stratification resulted in the formation of surface localized ionic clusters (SLICs). These …

Aqueous Raft Synthesis Of Stimuli-Responsive, Amphiphilic Block Copolymers And Self-Assembly Behavior In Solution And Incorporation Into Lbl Films, Matthew Grady Kellum

Dissertations

Of all the living radical polymerization techniques, reversible addition– fragmentation chain transfer (RAFT) polymerization is arguably the most versatile in terms of the reaction conditions (e.g. temperature and solvent selection), monomer selection (e.g. neutral, anionic, cationic, and zwitterionic), and purification. Since the introduction of RAFT in 1998, the McCormick research group and others including the Lowe, Sumerlin, and Davis research groups have synthesized a wide range of (co)polymers with predetermined molecular weights, low polydispersities, and advanced architectures utilizing aqueous RAFT (ARAFT) polymerization. These research groups have also studied how various block copolymers exhibit stimuli-responsive behavior due to a change in …

Multi Stimuli-Responsive Copolymers Obtained From Colloidal Dispersions, Fang Liu

Dissertations

This dissertation describes the design, synthesis, and development of multi stimuli-responsive random copolymers that exhibit collective responsiveness to temperature, pH or electromagnetic radiation. New colloidal particles of poly(N-(DL)-(1- Hydroxyymethyl) propylmethacrylamide/n-butyl acrylate) (p(DL-HMPMA/nBA) and poly(2-(N,N′-dimethylamino)ethyl methacrylate/n-butyl acrylate) (p(DMAEMA/nBA)) were synthesized, which upon coalesce to form solid continuous films. The presence of lower glass transition (Tg) nBA components not only facilitate film formation, but also provide sufficient free volume for polymer chain rearrangements. These studies showed that coalesced films exhibit 3D dimensional changes upon external stimuli, which are attributed to the collapse and conformational changes of stimuli-responsive components as well as buckling …

Perturbed Spherical Objects In Acoustic And Fluid Flow Fields, Manmeet Kaur

Dissertations

In this study, the time averaged acoustic radiation force and drag on a small, nearly spherical object suspended freely in a stationary sound wave field in a compressible, low viscosity fluid is to be calculated. This problem has been solved for a spherical object, and it has many important engineering applications related to segregation and separation processes for particles in fluids such as water. Small but significant errors have occurred in the predicted behavior of the particles using the existing approximate solutions based on perfect spheres. The classical approach has been extended in this research to objects that deviate slightly …

Algorithms In Comparative Genomics, Satish Chikkagoudar

Dissertations

The field of comparative genomics is abundant with problems of interest to computer scientists. In this thesis, the author presents solutions to three contemporary problems: obtaining better alignments for phylogeny reconstruction, identifying related RNA sequences in genomes, and ranking Single Nucleotide Polymorphisms (SNPs) in genome-wide association studies (GWAS).

Sequence alignment is a basic and widely used task in bioinformatics. Its applications include identifying protein structure, RNAs and transcription factor binding sites in genomes, and phylogeny reconstruction. Phylogenetic descriptions depend not only on the employed reconstruction technique, but also on the underlying sequence alignment. The author has studied and established a …

Understanding Cognitive Differences In Processing Competing Visualizations Of Complex Systems, Madhavi Mukul Chakrabarty

Dissertations

Node-link diagrams are used represent systems having different elements and relationships among the elements. Representing the systems using visualizations like node-link diagrams provides cognitive aid to individuals in understanding the system and effectively managing these systems. Using appropriate visual tools aids in task completion by reducing the cognitive load of individuals in understanding the problems and solving them. However, the visualizations that are currently developed lack any cognitive processing based evaluation. Most of the evaluations (if any) are based on the result of tasks performed using these visualizations. Therefore, the evaluations do not provide any perspective from the point of …

Integration Of Electronic And Optical Techniques In The Design And Fabrication Of Pressure Sensors, Ivan Padron

Dissertations

Since the introduction of micro-electro-mechanical systems fabrication methods, piezoresistive pressure sensors have become the more popular pressure transducers. They dominate pressure sensor commercialization due to their high performance, stability and repeatability. However, increasing demand for harsh environment sensing devices has made sensors based on Fabry-Perot interferometry the more promising optical pressure sensors due to their high degree of sensitivity, small size, high temperature performance, versatility, and improved immunity to environmental noise and interference. The work presented in this dissertation comprises the design, fabrication, and testing of sensors that fuse these two pressure sensing technologies into one integrated unit. A key …

Nonlinear Evolution Of Annular Layers And Liquid Threads In Electric Fields, Qiming Wang

Dissertations

The nonlinear dynamics of viscous perfectly conducting liquid jets or threads under the action of a radial electric field are studied theoretically and numerically here. The field is generated by a potential difference between the jet surface and a concentrically placed electrode of given radius. A long-wave nonlinear model that is used to predict the dynamics of the system and in particular to address the effect of the radial electric field on jet breakup is developed, Two canonical regimes are identified that depend on the size of the gap between the outer electrode and the unperturbed jet surface. For relatively …

Relationship Between Photospheric Magnetic Fields And Coronal Activities, Changyi Tan

Dissertations

Coronal emission comes in two forms, a steady component where the corona is heated to million degrees and a much hotter transient component of solar flares. Both components are known to be related to the evolution of surface magnetic fields. This dissertation studies the evolution of photospheric magnetic fields and flow fields and their relation to the properties of these two coronal emission components.

The key issue in the study of the steady coronal emission is the coronal heating problem: how the corona is heated to millions of degrees while the underlying solar photosphere is only a few thousand degrees. …

Job Seeking And Job Application In Social Networking Sites : Predicting Job Seekers' Behavioral Intentions, Maria Marcella Plummer

Dissertations

Social networking sites (SNSs) are revolutionizing the way in which employers and job seekers connect and interact with each other. Despite the reported benefits of SNSs with respect to finding a job, there are issues such as privacy concerns that might be deterring job seekers from using these sites in their attempts to secure a job. It is therefore important to understand the factors that are salient in predicting job seekers' use of SNSs in applying for jobs.

In this research, a theoretical model was developed to explicate job seekers' intentions to use SNSs to apply for jobs. Two aspects …

Semantics And Efficient Evaluation Of Partial Tree-Pattern Queries On Xml, Xiaoying Wu

Dissertations

Current applications export and exchange XML data on the web. Usually, XML data are queried using keyword queries or using the standard structured query language XQuery the core of which consists of the navigational query language XPath. In this context, one major challenge is the querying of the data when the structure of the data sources is complex or not fully known to the user. Another challenge is the integration of multiple data sources that export data with structural differences and irregularities. In this dissertation, a query language for XML called Partial Tree-Pattern Query (PTPQ) language is considered. PTPQs generalize …

Institutional Controls And Brownfield Redevelopment, Ronnachai Tiyarattanachai

Dissertations

Institutional controls (ICs) are used to reduce risks to human health and environment from exposure to contaminants at Brownfield sites. Regulators approve use of ICs in Brownfield redevelopment with the expectation that ICs will remain effective over the long-term under proper oversight mechanisms. However, a recent review of compliance statuses of Brownfield sites with ICs implemented in Massachusetts and New Jersey indicated a significant percentage of the sites are out of compliance status.

Implementation of ICs depends on compliance efforts by humans. Thus, consistency of implementation over the long-term is questionable because there are several potential problems due to human …

Modeling And Quasi-Monte Carlo Simulation Of Risk In Credit Portfolios, Bo Ren

Dissertations

Credit risk is the risk of losing contractually obligated cash flows promised by a counterparty such as a corporation, financial institution, or government due to default on its debt obligations. The need for accurate pricing and hedging of complex credit derivatives and for active management of large credit portfolios calls for an accurate assessment of the risk inherent in the underlying credit portfolios. An important challenge for modeling a credit portfolio is to capture the correlations within the credit portfolio. For very large and homogeneous portfolios, analytic and semi-analytic approaches can be used to derive limiting distributions. However, for portfolios …

Virtual World Commerce Adoption (Vwca) : A Case Study Of Second Life Investigating The Impacts Of Perceived Affordances, Trust, And Need Satisfaction, Kamolbhan Olapiriyakul

Dissertations

Virtual worlds are computer-simulated worlds in which multi-players can simultaneously interact in a rich graphical environment. The development of virtual worlds, along with the massive growth of users, creates opportunities for business organizations. This dissertation involves many studies regarding virtual world adoption in business by virtual consumers.

Most of the research in Information Systems (IS) was conducted investigating factors influencing technology adoption, such as ease of use and usefulness, subjective norms and behavioral controls, self-efficacy, performance and effort expectancy, flow, etc. However, most of these research studies focused neither on design aspects related to affordances nor users' goal-oriented behaviors, such …

Investigating Fabrication Methods For Micro Single-Chamber Solid Oxide Fuel Cells, Man Yang

Dissertations

A Solid Oxide Fuel Cell (SOFC) is a green energy technology that offers a cleaner and efficient alternative to fossil fuels. The efficiency and utility of SOFCs can be enhanced by fabricating miniaturized component structures within the fuel cell footprint. This research focuses on the microfabrication of parallel-connected inter-digitized design of micro single chamber SOFC (μ-SC-SOFCs). In this dissertation, candidate micro/nano fabrication techniques to precisely fabricate micro patterns on planar substrates have been studied. These include EBL, soft lithography, photolithography, and direct-writing. After analyzing preliminary results, two combinational approaches were further investigated. The first method involves the combination of the …

A Comparison Of Computer-Based Training And Traditional Classroom Training For The Sad Corporation Job Placement Team, Janice Brown Adams

Dissertations

Purpose: The purpose of this research study was to compare the effectiveness of computer-based training with traditional classroom training; both instructional delivery methods utilized the traditional classroom curriculum as a means of delivery for an on-the-job company-sponsored program. The JAW-SAD Human Resource Center (HRC) is a training facility for the SAD Corporation, a major international manufacturing company. The HRC is responsible for conducting continuous training and certification of SAD employees. Historically, training has been provided through conference workshops with a traditional classroom training format. The motivation and importance for this study was influenced by an administrative requirement to determine the …

Mastery Of Sixth-Grade Mathematics Expectations As Measured By The Seventh-Grade Michigan Education Assessment Program From 2005 To 2007, Marian Prince

Dissertations

Purpose

The purpose of this study is to document sixth-grade mathematics mastery as measured by the seventh-grade Michigan Education Assessment Program (MEAP) over a period of 3 years: 2005, 2006, and 2007. This study investigated whether mathematics performance in Michigan is related to ethnicity by analyzing student responses on the seventh-grade MEAP which evaluates students’ mastery of the Michigan sixth-grade mathematics expectations.

Method

Data from the Michigan Department of Education (MDE) containing the student scores of individual test items on the mathematics Michigan Education Assessment Program (MEAP) for seventh-grade students in Michigan for 2005 to 2007 formed the basis for …

Investigation Of Network Architecture Development And Properties In Thermoset Matrices, Jeremy Owen Swanson

Dissertations

Matrices employed in composite materials directly influence overall composite properties. In all thermoset materials, molecular level interactions and transformations during cure result in heterogeneous architecture. Variability in connectivity results from the often dramatic spatial and topological changes that occur during the crosslinking process. Compatibility (fillers, pigments, additives), temperature gradients and reactivity differences in the precursors only serve to increase the complexity of network formation. The objective of the research herein is to characterize and understand the relationships between cure conditions, conversion, connectivity, network architecture and properties in glassy thermosetting matrix resins.

In this research, epoxy and vinyl ester resins (VERs) …

Replacing Hydrogen Bonds With Coordinate Covalent Bonds In Coordination Networks, Colin Stewart Rodger

Dissertations

The overall theme of the dissertation is that metal ions such as silver(I) can replace H+ in hydrogen bonded organic frameworks. Because organic solids have been extensively studied, we can insert metal ions into the supramolecular assemblies, thus creating predictable coordination solids of varying dimensions. One example of an organic solid tested involves the organic compounds terephthalic and isophthalic acids. These dicarboxylic acids have previously been shown to self-assemble into tape-like structures via hydrogen bonding, with neighboring dicarboxylic acids located at angles of 180° and 120° respectively. By substituting the hydrogen bonds with coordination metal-ligand bonds similar assemblies are formed. …

Modulation Of Restriction Enzyme Pvuii Activity By Metal Ion Cofactors, Charulata Bhaskaran Prasannan

Dissertations

Metal ions like Ca2+, Mn2+, Tb3+, Eu3+ etc., can bind at the active site and have varying effects on the enzymatic activity. In a crystal structure with DNA, two Ca2+ ions were bound to the active site of each PvuII monomer, and the metals share the ligands. Ca2+ ions promote DNA binding and not cleavage in many nucleases. We explored the role of Mg2+ and Ca2+ binding at the metal binding sites of PvuII to elucidate the role of each metal site. We monitored the cleavage kinetics of PvuII in presence of mixed metals. The cleavage kinetics data for Ca2+ …

Study Of Thermal Frontal Polymerization Utilizing Reactive And Non-Reactive Additives, Veronika Grace Viner

Dissertations

Thermal frontal polymerization is a process that involves a propagating front travelling through a monomer/initiator solution and converting monomer into polymer. The effects of different reactive and non-reactive additives on front temperature, front velocity, and pot life were studied in a thermal frontal polymerization system of multifunctional acrylates. One issue with thermal frontal polymerization of acrylate monomers is the amount of smoke and fumes produced due to high front temperatures. The effect of thermally-expandable microspheres was studied utilizing a variety of monomers. Solid additives including fillers, inert phase changer materials, and high thermal conductive fillers were investigated. The addition of …

Reactor R&D: Synthesis And Optimization Of Metallic Nitride Fullerenes And The Introduction Of Two New Classes Of Endohedral Metallofullerenes, Metallic Nitride Azafullerenes And Oxo-Metallic Fullerenes, Curtis Earl Coumbe

Dissertations

Metallic nitride fullerenes (MNFs) were discovered in 1999. This class of endohedral fullerenes show promise in a new diverse range of useful applications. Since then, focus has shifted to the selective synthesis of these molecules with yields that would accommodate adequate sample distribution. Using the electric arc method, the traditional yield of these molecules has been very low (i.e. < 5 mg), and only a small percentage of the fullerene products (i.e. < 5%). This dissertation introduces the novel CAPTEAR (Chemically Adjusting Plasma Temperature, Energy, And Reactivity) method that allows the targeted synthesis of MNFs in high purity and yield. This method utilizes a nontraditional oxidizing method for fullerene synthesis that has not only provided optimization of MNFs, but also resulted in the discovery of two new classes of fullerenes: metallic nitride azafullerenes (MNAFs) and oxo-metallic fullerenes (OMFs). Evidence suggests that the nitrogen of the MNAF cage provides stability for the trimetallic nitride clusters, while the OMFs are the first fullerenes to encapsulate oxygen and incorporate a seven atom cluster inside a Cgo cage.

Other efforts to increase yields resulted from scaling up production of fullerenes by using larger quantities of starting materials. These larger quantities required energy (electrical current) beyond the capacity of the traditional electric arc generator. Therefore, a new electric arc generator …

Kendall's Tau And Spearman's Rho For Zero-Inflated Data, Ronald Silva Pimentel

Dissertations

Zero-inflated continuous distributions have positive probability mass at zero in addition to a continuous distribution. Such type of data can be encountered, for example, in medical, environmental and financial research. The main focus of this research is to study the association of nonnegative random variables, both having a positive probability mass at zero. New estimators of the classical measures of association, Kendall's tau and Spearman's rho, appropriate for the zero-inflated distributions, are proposed and their asymptotic distributions are derived. Performance of the estimators is assessed by a Monte Carlo simulation study. New ideas are illustrated by a real data example.

Metaevaluation Of Hiv/Aids Prevention Intervention Evaluations In Sub Saharan Africa With A Specific Emphasis On Implications For Women And Girls, Tererai Mafukidze Trent

Dissertations

Despite numerous attempts by international agencies to halt the spread of Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS), nowhere has the impact of HIV/AIDS been felt more acutely than among women and girls in Sub-Saharan Africa (SSA). SSA women account for 59% of adults over the age of 15 living with HIV/AIDS and 76% of those 15-24 who are infected (United Nations Joint Programme on HIV/AIDS [UNAIDS], 2007).

The evidence on gender disparities in infection rates is indisputable; there is an urgent need to identify what is missing in HIV/AIDS prevention interventions: What is the evidence based upon …

Theoretical Study Of Localized Surface Plasmons Of Metal Nanoparticles, Clusters And Embedded Metal Nanoparticles In Matrices, Masoud Shabani Nezhad Navrood

Dissertations

Localized surface plasmons resonances (LSPRs) in metallic nanoparticles (NPs) arise from the interactions between incident light and conduction electrons and have attracted enormous research interest in recent years both for their fundamental nature as well as applications in interdisciplinary areas of sciences such as biological imaging, plasmonic photo-thermal therapy, photovoltaics, and plasmonic sensors. LSPRs are strongly localized and depend on the shape, size, the composition of the NPs, the polarization direction of the incident light, refractive index (RI) of the surrounding medium as well as on the chemical environment that surrounded NPs. Although significant research has progressed both theoretically and …

Investigation Of Novel Thiol "Click" Reactions, Justin William Chan

Dissertations

The thio-Michael addition reaction is traditionally considered a base catalyzed reaction which involves high catalyst concentrations and long reaction times. This reaction utilizes potent, simple nucleophiles to catalyze the reaction, decreases the catalyst concentration and greatly increases the reaction times. The free radical mediated thiol-ene click reaction uses light or heat and an initiator to catalyze the rapid and quantitative addition of thiols to most electron rich enes without the formation of side products and in the absence of solvent. Recently, the thiol-ene click reaction has been exploited for these reasons in materials science and organic synthesis. The research herein …

Investigation Of The Relationship Between Polymer Structures And Thermal, Mechanical, Viscoelastic Properties, Ethem Kaya

Dissertations

The research presented in this dissertation involves four distinct areas: physical crosslinking systems, UV curable coatings for enhanced oxygen and carbon dioxide barrier properties, synthesis, and investigation of melting behavior/crystallinity relations of linear polyamides with long alkyl chains, and synthesis and characterization of cyclic diamides as precursors to linear polyamides 6 4.

The physical crosslinking section involves synthesis of monomers and polymers bearing cyclodextrin and adamantane pendent groups, and investigation of non-covalent interactions between these polymers (Chapter II). Two methacrylate monomers bearing cyclodextrin and adamantane were synthesized, and copolymerized with poly(ethylene glycol) methyl ether methacrylate. The specific interaction between copolymers …