Physical Sciences and Mathematics Commons^™

Development Of A Biosensor For Investigating Membrane Curvature Sorting, Joshua C. Black

Electronic Theses and Dissertations

The physical structure of cellular membranes plays a critical role in lipid and protein sorting. A novel biosensor was developed to probe the influence of curvature on sorting. This biosensor mimics large, two-dimensional membranes in dynamic equilibrium, achieves high spatial resolution between curvature and molecules of interest, and has high sensitivity, enough for single particle detection. The biosensor consists of continuous supported lipid bilayer formed over nanoparticles (40 to 200 nm diameter) deposited on a glass substrate. The nanoparticles determine the extent of curvature. This biosensor is the first to observe large-scale 2-dimensional diffusion of biomolecules on a supported lipid …

Defects And Dark Current In Organic Photovoltaics And Impacts On Device Physics, Xin Jiang

Electronic Theses and Dissertations

In this dissertation, we discussed the shape, energy level and density of defects in Organic Photovoltaic (OPV) devices by both theoretical and experimental methods. The energy band structure and intrinsic junctions of general standard and inverted OPV devices are investigated in detail. Transportation of separated holes and electrons in both structures are well analyzed. In chapter II, we developed a Monte-Carlo model to simulate charge transport process in organic materials. Marcus theory is applied to calculate the carrier transfer rate to build up hopping process in ideal lattices. Results of this model showed several properties of carriers regarding mobility, reorganization …

Geochemical Tracers Linking Submarine Groundwater Discharge To Hypoxia Formation In Long Bay, South Carolina, Usa, Sarah Lynn Chappell

Electronic Theses and Dissertations

Long Bay, South Carolina has experienced hypoxic conditions (<2mg/L dissolved oxygen) in the nearshore environment, not fully attributed to traditional formation mechanisms. Past research suggested physical, biological, and/or anthropogenic influences on low dissolved oxygen levels. This project aimed to determine the contribution of submarine groundwater discharge (SGD) to hypoxia formation. We measured activities of 222Rnxs, 224Raxs, 223Ra, 228Ra, and 226Ra (3.8d, 3.6d, 11.5d, 5.8yr, 1600yr half-lives, respectively) in nearshore bottom waters from April 2012 through April 2013. Radium activities observed during a hypoxic event on 16-Aug-2012 were up to an order of magnitude higher than those seen during oxic conditions and the highest ever observed in the open ocean, to our knowledge. We determined that a hypoxic water mass, comprised heavily of offshore anoxic SGD, migrated inshore due to physical conditions constraining mixing over a two week time period. High groundwater content suggests that observed hypoxic conditions in nearshore Long Bay may be independent of biological influence once offshore SGD occurs.

Packings And Coverings Of Complete Graphs With A Hole With The 4-Cycle With A Pendant Edge, Yan Xia

Electronic Theses and Dissertations

In this thesis, we consider packings and coverings of various complete graphs with the 4-cycle with a pendant edge. We consider both restricted and unrestricted coverings. Necessary and sufficient conditions are given for such structures for (1) complete graphs K_v, (2) complete bipartite graphs K_m,n, and (3) complete graphs with a hole K(v,w).

Synthesis Of Ester Derivatives Of Resveratrol As Potential Anti-Cancer Drugs, Parasmani Pageni

Electronic Theses and Dissertations

Resveratrol is a naturally occurring phytoalexin of the stilbene family produced by various plants in response to stress, UV radiation, and fungal attack. It is primarily found in peanuts, berries, grape skin, and red wine. Resveratrol has been found to exhibit anti-cancer, anti-inflammatory, anti-aging, and anti-oxidant properties. Research indicates that diets enriched with resveratrol containing substances result in less incidence of cancer. Unfortunately, the low bioavailability and solubility has been a huge setback for its potential prospects. As a result, efforts have been made to synthesize derivatives of resveratrol with increased solubility and bioavailability. Three triester novel resveratrol derivatives 3, …

Systematics, Climate, And Ecology Of Fossil And Extant Nyssa (Nyssaceae, Cornales) And Implications Of Nyssa Grayensis Sp. Nov. From The Gray Fossil Site, Northeast Tennessee, Nathan R. Noll

Electronic Theses and Dissertations

The Late Hemphillian (latest Miocene or earliest Pliocene, 7-4.5 Ma) Gray Fossil Site in northeastern Tennessee is interpreted to represent a lacustrine paleokarst fed by a river or stream. This research focuses on the morphological and systematic relations of Nyssa endocarps (fruit pits) from the fossil site to extinct and extant Nyssa species. A combination of metric and nonmetric traits allows recognition of a new species: Nyssa grayensis sp. nov. This fossil species shares the most similarities with the extant Nyssa ogeche Bartram ex Marshall from southeast North America and the Eocene fossil Nyssa eolignitica Berry from western Tennessee. Affinities …

X-Ray Crystal Structures Of: [Rh2(N-{2,4,6-Ch3}C6h2)Coch3)4]•2ncc6h4 And Ba1.5[Fe(C10h13n2o7)][Co(Cn)6]•9h2o; Two Crystallographic Challenges, Kenneth K. Kpogo

Electronic Theses and Dissertations

The novel compound, [Rh₂(N-{2,4,6-CH₃}C₆H₂)COCH₃)₄] was synthesized. Crystal structures of [Rh₂(N-{2,4,6-CH₃}C₆H₂)COCH₃)₄]·2NCC₆H₅ and Ba_1.5[Fe(C₁₀H₁₃N₂O₇)][Co(CN)₆]·9H₂O were determined employing a Rigaku Mercury375R/M CCD (XtaLAB mini) diffractometer with graphite monochromated Mo-Kα radiation. For [Rh₂(N-{2,4,6-CH₃}C₆H₂)COCH₃)₄]·2NCC₆H₅, the space group was P-421c(#114) with unit cell dimensions: a =11.0169(14)Å, c =21.499(3)Å, V …

A Glyptosaurine Lizard From The Eocene (Late Uintan) Of San Diego, California, And Implications For Glyptosaurine Evolution And Biogeography, David Moscato

Electronic Theses and Dissertations

Glyptosaurinae is an extinct subfamily of lizards of the family Anguidae. Glyptosaurine lizards are known exclusively from the Paleogene of North America and Eurasia, reaching their peak of diversity and distribution in the Eocene. In North America these lizards are largely restricted to the intermontane basins along the Rocky Mountain range, with only sparse, indeterminately-identified skeletal elements known from outside of this region. Glyptosaurine lizards are split into two tribes: the monophyletic Glyptosaurini and paraphyletic “Melanosaurini”. Within Glyptosaurini, the most common and widespread genus is Glyptosaurus. In this study I describe a new specimen assignable to G. sylvestris, …

Human Action Recognition Via Fused Kinematic Structure And Surface Representation, Salah R. Althloothi

Electronic Theses and Dissertations

Human action recognition from visual data has remained a challenging problem in the field of computer vision and pattern recognition. This dissertation introduces a new methodology for human action recognition using motion features extracted from kinematic structure, and shape features extracted from surface representation of human body. Motion features are used to provide sufficient information about human movement, whereas shape features are used to describe the structure of silhouette. These features are fused at the kernel level using Multikernel Learning (MKL) technique to enhance the overall performance of human action recognition. In fact, there are advantages in using multiple types …

A Paleoenvironmental Investigation Of Eolian Influx In Lacustrine Sediments Of The Southern Rocky Mountain Region, Rebecca L. Brice

Electronic Theses and Dissertations

Potential indications of long-term trends in paleoclimate, specifically winds, in the Southern Rocky Mountain region of the United States were tested using lacustrine sediment from South Blue Lake in the Wet Mountains of Colorado. This study builds upon existing eolian and lacustrine research, and investigates paleowind in a location not yet studied in this manner. Variability in sediment laminae, particle size, and mineralogy show similar patterns during the mid-Holocene warm period (ca. 5500 cal. yr BP - ca. 6000 cal. yr BP). These patterns indicate a warmer, drier, windier period that is contrasted by a less variable period in the …

Mixture Of Poisson Distributions To Model Discrete Stock Price Changes., Rasitha Rangani Jayasekare Kodippuli Thanthillage Dona

Electronic Theses and Dissertations

An application of a mixture of Poisson distributions is proposed to model the discrete changes in stock price based on the minimum price movement known as `tick-size'. The parameters are estimated using the Expectation-Maximization (EM) algorithm with a constant mixing probability as well as mixing probabilities which depend on order size. The model is evaluated using simulations and real data. Both the simulated and real data show reasonable estimates. Several adjustments are made to the model implementation to improve the efficiency with user written codes for the Newton Raphson algorithm and also implementing one of the most recent versions of …

Loops And Their Permutation Groups, Mark Greer

Electronic Theses and Dissertations

This dissertation uses the connections between loops and their associated permutation groups to study certain varieties of loops. We first define a variety of loops generalizing commutative automorphic loops and show this new variety is power associative. We show a correspondence to Bruck loops of odd order and use this correspondence to give structural results for our new variety, which in turn hold for commutative automorphic loops. Next, we study a variety of loops that generalize both Moufang and Steiner loops. We extend on known results for Moufang loops and then extend two different doubling constructions for creating Moufang and …

Using Hydrologic Measurements To Investigate Free Phase Gas In A Maine Peatland, Usa, Christiaan Bon

Electronic Theses and Dissertations

Northern Peatlands cover more than 350 million ha (~3 percent of Earth’s surface) and are an important source of methane (CH4) and other biogenic gases contributing to climate change. Free phase gas (FPG) accumulation and episodic release has recently been recognized as an important mechanism for biogenic gas flux from peatlands. It is likely that gas production and groundwater flow are interconnected in peatlands: groundwater flow influences gas production by regulating geochemical conditions and nutrient supply available for methanogenesis while FPG influences groundwater flow through a reduction in peat permeability and by creating excess pore fluid pressures. Water samples collected …

Universal Cycles For Some Combinatorial Objects, Andre A. Campbell

Electronic Theses and Dissertations

A de Bruijn cycle commonly referred to as a universal cycle (u-cycle), is a complete and compact listing of a collection of combinatorial objects. In this paper, we show the power of de Bruijn's original theorem, namely that the cycles bearing his name exist for n-letter words on a k-letter alphabet for all values of k,n, to prove that we can create de Bruijn cycles for multi-sets using natural encodings and M-Lipschitz n-letter words and the assignment of elements of [n]={1,2,...,n} to the sets in any labeled subposet of the Boolean lattice; de Bruijn's theorem corresponds to the case …

Restricted And Unrestricted Coverings Of Complete Bipartite Graphs With Hexagons, Wesley M. Surber

Electronic Theses and Dissertations

A minimal covering of a graph G with isomorphic copies of graph H is a set {H₁, H₂, H₃, ... , H_n} where H_i is isomorphic to H, the vertex set of H_i is a subset of G, the edge set of G is a subset of the union of H_i's, and the cardinality of the union of H_i's minus G is minimum. Some studies have been made of covering the complete graph in which case an added condition of the edge set of H_{i …}

Improving The Performance Of The Parallel Ice Sheet Model On A Large-Scale, Distributed Supercomputer, Timothy J. Morey

Electronic Theses and Dissertations

In this thesis, we describe our work to understand and improve the performance and scalability of the Parallel Ice Sheet Model (PISM) on the Ranger supercomputer. PISM enables the simulation of large-scale ice sheets, such as those found in Greenland and Antarctica, which are of particular interest to climate scientists due to their potential to contribute to sea-level rise.

PISM has a unique parallel architecture that is designed to take advantage of the computational resources available on state-of-the-art supercomputers. The problem, however, is that even though PISM can run without modifcation on a supercomputer, it is generally unable to do …

A Comparison Of Leading Database Storage Engines In Support Of Online Analytical Processing In An Open Source Environment, Gabriel Tocci

Electronic Theses and Dissertations

Online Analytical Processing (OLAP) has become the de facto data analysis technology used in modern decision support systems. It has experienced tremendous growth, and is among the top priorities for enterprises. Open source systems have become an effective alternative to proprietary systems in terms of cost and function. The purpose of the study was to investigate the performance of two leading database storage engines in an open source OLAP environment. Despite recent upgrades in performance features for the InnoDB database engine, the MyISAM database engine is shown to outperform the InnoDB database engine under a standard benchmark. This result was …

Study Of Immobilizing Cadmium Selenide Quantum Dots In Selected Polymers For Application In Peroxyoxalate Chemiluminescence Flow Injection Analysis, Christopher S. Moore

Electronic Theses and Dissertations

Two batches of CdSe QDs with different sizes were synthesized for immobilizing in polyisoprene (PI), polymethylmethacrylate (PMMA), and low-density polyethylene (LDPE). The combinations of QDs and polymer substrates were evaluated for their analytical fit-for-use in applicable immunoassays. Hydrogen peroxide standards were injected into the flow injection analyzer (FIA) constructed to simulate enzyme-generated hydrogen peroxide reacting with bis-(2,4,6-trichlorophenyl) oxalate.

Linear correlations between hydrogen peroxide and chemilumenscent intensities yielded regression values greater than 0.9750 for hydrogen peroxide concentrations between 1.0 x 10^-4 M and 1.0 x 10^-1 M. The developed technique’s LOD was approximately 10 ppm. Variability of the prepared …

A Variety Of Proofs Of The Steiner-Lehmus Theorem, Sherri R. Gardner

Electronic Theses and Dissertations

The Steiner-Lehmus Theorem has garnered much attention since its conception in the 1840s. A variety of proofs resulting from the posing of the theorem are still appearing today, well over 100 years later. There are some amazing similarities among these proofs, as different as they seem to be. These characteristics allow for some interesting groupings and observations.

Level Crossing Times In Mathematical Finance, Ofosuhene Osei

Electronic Theses and Dissertations

Level crossing times and their applications in finance are of importance, given certain threshold levels that represent the "desirable" or "sell" values of a stock. In this thesis, we make use of Wald's lemmas and various deep results from renewal theory, in the context of finance, in modelling the growth of a portfolio of stocks. Several models are employed .

A New Species Of Teleoceras From The Late Miocene Gray Fossil Site, With Comparisons To Other North American Hemphillian Species, Rachel A. Short

Electronic Theses and Dissertations

A thorough morphological description of Teleoceras material from the Gray Fossil Site, Gray, Tennessee is provided. This is the only record of a browsing Teleoceras and, as a late Hemphillian locality, represents one of the youngest populations. Linear measurements of post-cranial elements indicate proportional differences between Teleoceras from the Gray Fossil Site and those from other Hemphillian localities. These differences are more pronounced in the elements of the forelimb than in those of the hind limb. Statistical analyses of post-cranial elements from 3 Hemphillian species of Teleoceras suggest that these differences should not be used to separate species. However, the …

Identifying Myotis Species Using Geometric Morphometrics And Its Implications For The Fossil Record And Conservation, Kyle J. Jansky

Electronic Theses and Dissertations

Dentaries of the 6 species of Myotis that occur in the eastern United States were analyzed using landmark-based geometric morphometrics. The species could be distinguished with a high degree of accuracy. Evidence was found of a phylogenetic signal in the morphology of the Neotropical and Nearctic Myotis sub-clades. There is also evidence of convergence in the morphology of the dentary among Myotis species that feed primarily by gleaning. When analyzed together there was no evidence of sexual dimorphism among the 6 eastern U.S. Myotis, but when analyzed individually some dimorphism may be present. A sample of fossil Myotis of …

Analysis Of The Blancan Procyonids Of Florida, Laura S. Gilmore

Electronic Theses and Dissertations

Procyonids are well known biologically but knowledge of their fossil record is comparatively sparse. This study seeks to describe a sample of late Blancan procyonid fossils composed mostly of postcranial and dental material. Fossils are analyzed using linear and 2D geometric morphometrics and compared with a large sample of modern specimens from a wide geographic area to understand the range of intraspecific variation. The large Procyon species is described as a new taxon based on morphology of the postcrania and lower dentition, while another Procyon species is also described as new due to an apomorphy in the upper dentition. A …

Very Cost Effective Partitions In Graphs, Inna Vasylieva

Electronic Theses and Dissertations

For a graph G=(V,E) and a set of vertices S, a vertex v in S is said to be very cost effective if it is adjacent to more vertices in V -S than in S.

A bipartition pi={S, V- S} is called very cost effective if both S and V- S are very cost effective sets. Not all graphs have a very cost effective bipartition, for example, the complete graphs of odd order do not. We consider several families of graphs G, including Cartesian products and cacti graphs, to determine whether G has a very cost effective bipartition.

Peg Solitaire On Trees With Diameter Four, Clayton A. Walvoort

Electronic Theses and Dissertations

In a paper by Beeler and Hoilman, the traditional game of peg solitaire is generalized to graphs in the combinatorial sense. One of the important open problems in this paper was to classify solvable trees. In this thesis, we will give necessary and sufficient conditions for the solvability for all trees with diameter four. We also give the maximum number of pegs that can be left on such a graph under the restriction that we jump whenever possible.

A Mathematical Model For Antibiotic Resistance In A Hospital Setting With A Varying Population, Edward H. Snyder

Electronic Theses and Dissertations

Antibiotic-resistant bacteria(ARB) is causing increased health risk and cost to society. Mathematical models have been developed to study the transmission of resistant bacteria and the efficacy of preventive measures to slow its spread within a hospital setting. The majority of these models have assumed a constant total hospital population with the admission and discharge rates being equal throughout the duration. But a typical hospital population varies from day to day and season to season. In this thesis, we apply variable admission and discharge daily rates to existing deterministic and stochastic models which examine the transmission of single and dual resistant …

Compound Identification Using Penalized Linear Regression., Ruiqi Liu

Electronic Theses and Dissertations

In this study, we propose a new method for compound identification using penalized linear regression. Compound identification is often achieved by matching the experimental mass spectra to the mass spectra stored in a reference library based on mass spectral similarity. In the context of the linear regression, the response variable is an experimental mass spectrum (i.e., query) and all the compounds in the reference library are the independent variables. However, the number of compounds in the reference library is much larger than the range of m/z values so that the data become high dimensional data with suffering from singularity. For …

Holocene Glacial History Of Renland, East Greenland Reconstructed From Lake Sediments, Aaron Medford

Electronic Theses and Dissertations

The Arctic is responding to the modern increase in temperature, resulting in ice loss and consequent sea-level rise. In order to understand present-day changes, we need to understand how the Arctic has reacted in the past to natural variations in climate forcing. To begin to identify the mechanisms behind climate change, I produced a Holocene glacial and climate record for the Renland Ice Cap, Scoresby Sund, East Greenland, from sediments in glacially fed lakes. I cored Rapids and Bunny Lakes, which are fed by meltwater from the Renland Ice Cap, as well as Raven Lake, which does not receive glacial …

Variational Methods On Elastic Curves, Daniel D. Rocker

Electronic Theses and Dissertations

In this thesis we investigate elastic curves. These are curves with minimal bending energy as measured by the total squared curvature functional. We show that these can be computed by evolving curves in the direction of the negative gradient in certain Hilbert space settings. By discretizing the curves and using numerical integration, we compute approximate minimizers and display using computer graphics. We propose a conjecture based on the rotation number of a curve that predicts the critical point curves that minimize bending energy.

Using Neural Networks To Provide Local Weather Forecasts, Andrew Culclasure

Electronic Theses and Dissertations

Artificial neural networks (ANNs) have been applied extensively to both regress and classify weather phenomena. While one of the core strengths of neural networks is rendering accurate predictions with noisy datasets, there is currently not a significant amount of research focusing on whether ANNs are capable of producing accurate forecasts of relevant weather variables from small-scale, imperfect datasets. Also, there is not a significant amount of research focusing on the forecasting performance of neural networks applied to weather datasets that have been temporally rolled-up from a base dataset. In this paper, a survey of existing research on applying ANNs to …