Physical Sciences and Mathematics Commons^™

Challenges For Estimating The Global Prevalence Of Micronutrient Deficiencies And Related Disease Burden: A Case Study Of The Global Burden Of Disease Study, Sonja Y. Hess, Alexander C. Mclain Ph.D., Edward A. Frongillo Jr. Ph.D., Ashkan Afshin, Nicholas J. Kassebaum, Saskia Jm Osendarp, Reed Atkin, Rahul Rawat, Kenneth H. Brown

Faculty Publications

Information on the prevalence of micronutrient deficiencies is needed to determine related disease burden; underpin evidence-based advocacy; and design, deliver, and monitor safe, effective interventions. Assessing the global prevalence of deficiency requires a valid micronutrient status biomarker with an appropriate cutoff to define deficiency and relevant data from representative surveys across multiple locations and years. The Global Burden of Disease Study includes prevalence estimates for iodine, iron, zinc, and vitamin A deficiencies, for which recommended biomarkers and appropriate deficiency cutoffs exist. Because representative survey data are lacking, only retinol concentration is used to model vitamin A deficiency, and proxy indicators …

Nonsingular Quantum Gravitational Dynamics Of An Lemaitre-Tolman-Bondi Dust Shell Model: The Role Of Quantization Prescriptions, Kristina Giesel, Bao-Fei Li, Parampreet Singh

Faculty Publications

We study some consequences of the loop quantization of the outermost dust shell in the LemaitreTolman-Bondi spacetime with a homogeneous dust density using different quantization strategies motivated by loop quantum gravity. Prior work has dealt with loop quantizing this model by employing holonomies and the triads, following the procedure in standard loop quantum cosmology. In this work we compare this quantization with the one in which holonomies and gauge-covariant fluxes are used. While both of the quantization schemes resolve the central singularity, they lead to different mass gaps at which a trapped surface forms. This trapped surface which is matched …

A Healthy Dietary Pattern With A Low Inflammatory Potential Reduces The Risk Of Gestational Diabetes Mellitus, Lotta Pajunen, Liisa Korkalo, Noora Houttu, Outi Pellonperä, Kati Mokkala, Nitin Shivappa Mbbs, Mph, Ph.D., James Hébert Scd, Tero Vahlberg, Kristina Tertti, Kirsi Laitinen

Faculty Publications

Purpose An optimal diet for lowering the risk of gestational diabetes mellitus (GDM) is still to be defined, but may comprise of nutrient intakes, dietary patterns, diet quality, and eating frequency. This study was designed to investigate the contribution of diet in developing GDM in a comprehensive way. Methods The dietary intake of overweight or obese women, a risk group for GDM (n = 351), was assessed using 3-day food diaries and diet quality questionnaires in early pregnancy. Eating frequency and nutrient intakes were calculated, and dietary patterns identified using principal component analysis. The inflammatory potential of the diet was …

Monitoring Fine-Scale Forest Health Using Unmanned Aerial Systems (Uas) Multispectral Models, Benjamin T. Fraser, Russell G. Congalton

Faculty Publications

Forest disturbances—driven by pests, pathogens, and discrete events—have led to billions of dollars in lost ecosystem services and management costs. To understand the patterns and severity of these stressors across complex landscapes, there must be an increase in reliable data at scales compatible with management actions. Unmanned aerial systems (UAS or UAV) offer a capable platform for collecting local scale (e.g., individual tree) forestry data. In this study, we evaluate the capability of UAS multispectral imagery and freely available National Agricultural Imagery Program (NAIP) imagery for differentiating coniferous healthy, coniferous stressed, deciduous healthy, deciduous stressed, and degraded individual trees throughout …

Adsorption Of Helium On A Charged Propeller Molecule: Hexaphenylbenzene, Siegfried Kollotzek, Florent Calvo, Serge Krasnokutski, Fabio Zappa, Paul Scheier, Olof E. Echt

Faculty Publications

Physisorption on planar or curved graphitic surfaces or aromatic rings has been investigated by various research groups, but in these studies the substrate was usually strictly rigid. Here we report a combined experimental and theoretical study of helium adsorption on cationic hexaphenylbenzene (HPB), a propeller-shaped molecule. The orientation of its propeller blades is known to be sensitive to the environment, with substantial differences between the molecule in the gas phase and in the crystalline solid. Mass spectra of He_nHPB⁺, synthesized in helium nanodroplets, indicate enhanced stability for ions containing n = 2, 4, 14, 28, 42, …

Assessing Population Exposure To Coastal Flooding Due To Sea Level Rise, Matthew E. Hauer, Dean Hardy, Scott A. Kulp, Valerie Mueller, David J. Wrathall, Peter U. Clark

Faculty Publications

The exposure of populations to sea-level rise (SLR) is a leading indicator assessing the impact of future climate change on coastal regions. SLR exposes coastal populations to a spectrum of impacts with broad spatial and temporal heterogeneity, but exposure assessments often narrowly define the spatial zone of flooding. Here we show how choice of zone results in differential exposure estimates across space and time. Further, we apply a spatio-temporal flood-modeling approach that integrates across these spatial zones to assess the annual probability of population exposure. We apply our model to the coastal United States to demonstrate a more robust assessment …

Two-Dimensional Steady Boussinesq Convection: Existence, Computation And Scaling, Jeremiah S. Lane, Benjamin F. Akers Benjamin.Akers@Afit.Edu

Faculty Publications

This research investigates laser-induced convection through a stream function-vorticity formulation. Specifically, this paper considers a solution to the steady Boussinesq Navier–Stokes equations in two dimensions with a slip boundary condition on a finite box. A fixed-point algorithm is introduced in stream function-vorticity variables, followed by a proof of the existence of steady solutions for small laser amplitudes. From this analysis, an asymptotic relationship is demonstrated between the nondimensional fluid parameters and least upper bounds for laser amplitudes that guarantee existence, which accords with numerical results implementing the algorithm in a finite difference scheme. The findings indicate that the upper bound …

Causal Effects On Low Apgar At 5-Min And Stillbirth In A Malaria Maternal–Fetal Health Outcome Investigation: A Large Perinatal Surveillance Study In The Brazilian Amazon, Julio Abel Seijas-Chávez, Melissa Nolan Ph.D., Mph, Mary K. Lynn, Maria José Francalino Da Rocha, Muana Da Costa Araújo, Fernando Luiz Affonso Fonseca, Gabriel Zorello Laporta

Faculty Publications

Background

Malaria elimination in Brazil poses several challenges, including the control of Plasmodium falciparum foci and the hidden burden of Plasmodium vivax in pregnancy. Maternal malaria and fetal health outcomes were investigated with a perinatal surveillance study in the municipality of Cruzeiro do Sul, Acre state, Brazilian Amazon. The research questions are: what are the causal effects of low birth weight on low Apgar at 5-min and of perinatal anaemia on stillbirth?

Methods

From November 2018 to October 2019, pregnant women of ≥ 22 weeks or puerperal mothers, who delivered at the referral maternity hospital (Juruá Women and Children’s Hospital), …

Constraints From Ligo O3 Data On Gravitational-Wave Emission Due To R-Modes In The Glitching Pulsar Psr J0537-6910, Ligo Scientific Collaboration, Virgo Collaboration, Kagra Collaboration, Tiffany Z. Summerscales

Faculty Publications

We present a search for continuous gravitational-wave emission due to r-modes in the pulsar PSR J0537–6910 using data from the LIGO–Virgo Collaboration observing run O3. PSR J0537–6910 is a young energetic X-ray pulsar and is the most frequent glitcher known. The inter-glitch braking index of the pulsar suggests that gravitational-wave emission due to r-mode oscillations may play an important role in the spin evolution of this pulsar. Theoretical models confirm this possibility and predict emission at a level that can be probed by ground-based detectors. In order to explore this scenario, we search for r-mode emission in the epochs between …

The Dietary Inflammatory Index Is Not Associated With Gut Permeability Or Biomarkers Of Systemic Inflammation In Hiv Immunologic Non-Responders, Fat Malazogu, Rodney K. Rousseau, Nitin Shivappa Mbbs, Mph, Ph.D., Sanja Huibner, Sharon L. Walmsley, Colin M. Kovacs, Erika Benko, Robert J. Reinhard, Ron Rosenes, James R. Hébert, Rupert Kaul

Faculty Publications

Immunologic non-responders (INRs) are a subset of individuals living with HIV who have suboptimal blood CD4+ T cell recovery despite effective antiretroviral therapy (ART). They are at an increased risk of serious non-AIDS co-morbidities and death, and demonstrate enhanced systemic immune activation. In other populations diet has been correlated with markers of systemic inflammation through the Diet Inflammatory Index (DII), but this association has not been studied in persons living with HIV (PLWH). Blood was collected from 28 INR PLWH with a blood CD4+ T cell count <350/μL despite ≥2 years of effective ART. Participants completed a Canadian Diet History Questionnaire, and their responses were used to calculate the DII. Plasma inflammatory markers (IFNγ, TNF, IL-6, sVCAM, D-dimer, sCD14 and CRP) were assayed by ELISA, cellular immune activation (HLA-DR and CD38 on CD4+ and CD8+ T cells) was quantified using flow cytometry, and small bowel permeability assessed by calculation of the urine LacMan ratio after drinking a mix of lactulose and mannitol. Participants were a median age of 57 years, had been on effective ART for 15 years, and the median DII was −1.91 (range of −3.78 to +2.23). No correlation was observed between DII and plasma markers of inflammation, levels of T cell activation, gut permeability, or the biomarker of bacterial translocation sCD14. Self-reported alcohol intake, a potential confounder of the relationship between diet and inflammatory biomarkers, was also not associated with systemic inflammation or gut permeability. Our findings suggest that other mechanisms, rather than diet, are likely to be the major driver of systemic inflammation in INR individuals.

Association Between Diet Quality Indices And Incidence Of Type 2 Diabetes In The Melbourne Collaborative Cohort Study, Allison M. Hodge, Md Nazmul Karim, James Hébert Scd, Nitin Shivappa Mbbs, Mph, Ph.D., Barbora De Courten

Faculty Publications

Type 2 diabetes mellitus is a common condition whose incidence is increasing worldwide, and for which obesity and diet are important risk factors. The aim of this study was to assess the association of three diet quality scores with diabetes risk and how much of the association was mediated through body size. The Melbourne Collaborative Cohort Study recruited 41,513 men and women aged 40–69 years during 1990–1994. At baseline, data were collected on lifestyle and diet, anthropometric measures were performed. Incident diabetes was assessed by self-report at follow-up surveys in 1994–1998 and 2003–2007. The associations between the dietary inflammatory index …

Precise Measurement Of The D0 And D+ Lifetimes At Belle Ii, F. Abudin´En, I. Adachi, K. Adamczyk, L. Aggarwal, H. Ahmed, H. Aihara, N. Akopov, A. Aloisio, N. Anh Ky, D. M. Asner, H. Atmacan, V. Aushev, V. Babu, S. Bacher, H. Bae, S. Baehr, S. Bahinipati, P. Bambade, Milind Purohit, Et. Al.

Faculty Publications

We report a measurement of the D⁰ and D⁺ lifetimes using D⁰ → K⁻π⁺ and D⁺ → K⁻π⁺π⁺ decays reconstructed in e⁺e⁻ → cc̅ data recorded by the Belle II experiment at the SuperKEKB asymmetricenergy e⁺e⁻ collider. The data, collected at center-of-mass energies at or near the ϒ(4S) resonance, correspond to an integrated luminosity of 72 fb⁻¹. The results, _τ(D⁰) = 410.5 plusmn;1.1_(stat) 0.8(syst) fs and τ(D⁺) = 1030.4 plusmn; 4.7(stat) 3.1(syst) …

All-Sky Search For Long-Duration Gravitational-Wave Bursts In The Third Advanced Ligo And Advanced Virgo Run, Ligo Scientific Collaboration, Virgo Collaboration, Kagra Collaboration, Tiffany Z. Summerscales

Faculty Publications

After the detection of gravitational waves from compact binary coalescences, the search for transient gravitational-wave signals with less well-defined waveforms for which matched filtering is not well suited is one of the frontiers for gravitational-wave astronomy. Broadly classified into “short” ≲1  s and “long” ≳1  s duration signals, these signals are expected from a variety of astrophysical processes, including non-axisymmetric deformations in magnetars or eccentric binary black hole coalescences. In this work, we present a search for long-duration gravitational-wave transients from Advanced LIGO and Advanced Virgo’s third observing run from April 2019 to March 2020. For this search, we use …

Search For Active-Sterile Antineutrino Mixing Using Neutral-Current Interactions With The Nova Experiment, M. A. Acero, P. Adamson, L. Aliaga, N. Anfimov, A. Antoshkin, E. Arrieta-Diaz, L. Asquith, A. Aurisano, A. Back, C. Backhouse, M. Baird, N. Balashov, P. Baldi, B. A. Bambah, S. Bashar, K. Bays, R. Bernstein, B. Bhatnagar, B. Bhuyan, J. Bian, Roberto Petti, Et. Al.

Faculty Publications

This Letter reports results from the first long-baseline search for sterile antineutrinos mixing in an accelerator-based antineutrino-dominated beam. The rate of neutral-current interactions in the two NOvA detectors, at distances of 1 and 810 km from the beam source, is analyzed using an exposure of 12.51×10²⁰ protons-on-target from the NuMI beam at Fermilab running in antineutrino mode. A total of 121 of neutral-current candidates are observed at the far detector, compared to a prediction of 122±11(stat.)±15(syst.) assuming mixing only between three active flavors. No evidence for ⊽ _{μ →} ⊽ _s oscillation is observed. Interpreting this result within a …

Association Between Neighborhood Social Deprivation And Stage At Diagnosis Among Breast Cancer Patients In South Carolina, Oluwole Adeyemi Babatunde, Whitney Zahnd Ph.D., Jan Eberth Ph.D., Andrew B. Lawson, Swann Arp Adams, Eric Adjei Boakye, Melanie S. Jefferson, Caitlin G. Allen, John L. Pearce, Hong Li, Chanita Hughes Halbert

Faculty Publications

The purpose of this study was to examine the association between neighborhood social deprivation and individual-level characteristics on breast cancer staging in African American and white breast cancer patients. We established a retrospective cohort of patients with breast cancer diagnosed from 1996 to 2015 using the South Carolina Central Cancer Registry. We abstracted sociodemographic and clinical variables from the registry and linked these data to a county-level composite that captured neighborhood social conditions—the social deprivation index (SDI). Data were analyzed using chi-square tests, Student’s t-test, and multivariable ordinal regression analysis to evaluate associations. The study sample included 52,803 female patients …

The Poissonian Origin Of Power Laws In Solar Flare Waiting Time Distributions, Markus J. Aschwanden, Jay R. Johnson

Faculty Publications

In this study we aim for a deeper understanding of the power-law slope, α, of waiting time distributions. Statistically independent events with linear behavior can be characterized by binomial, Gaussian, exponential, or Poissonian size distribution functions. In contrast, physical processes with nonlinear behavior exhibit spatiotemporal coherence (or memory) and "fat tails" in their size distributions that fit power-law-like functions, as a consequence of the time variability of the mean event rate, as demonstrated by means of Bayesian block decomposition in the work of Wheatland et al. In this study we conduct numerical simulations of waiting time distributions N( …

Optically Active Selenium Vacancies In Baga4Se7 Crystals, Brian C. Holloway [*], Timothy D. Gustafson, Christopher A. Lenyk, Nancy C. Giles, Kevin T. Zawilski, Peter G. Schunemann, Kent L. Averett, Larry E. Halliburton

Faculty Publications

Barium gallium selenide (BaGa₄Se₇) is a recently developed nonlinear optical material with a transmission window extending from 470 nm to 17 μm. A primary application of these crystals is the production of tunable mid-infrared laser beams via optical parametric oscillation. Unintentional point defects, such as selenium vacancies, cation vacancies (barium and/or gallium), and trace amounts of transition-metal ions, are present in BaGa₄Se₇ crystals and may adversely affect device performance. Electron paramagnetic resonance (EPR) and optical absorption are used to identify and characterize these defects. Five distinct EPR spectra, each representing an electron …

Searches For Continuous Gravitational Waves From Young Supernova Remnants In The Early Third Observing Run Of Advanced Ligo And Virgo, Ligo Scientific Collaboration, Virgo Collaboration, Kagra Collaboration, Tiffany Z. Summerscales

Faculty Publications

We present results of three wide-band directed searches for continuous gravitational waves from 15 young supernova remnants in the first half of the third Advanced LIGO and Virgo observing run. We use three search pipelines with distinct signal models and methods of identifying noise artifacts. Without ephemerides of these sources, the searches are conducted over a fRequency band spanning from 10 to 2 kHz. We find no evidence of continuous gravitational radiation from these sources. We set upper limits on the intrinsic signal strain at 95% confidence level in sample subbands, estimate the sensitivity in the full band, and derive …

Search Full Text Options Here 1 Of 1 Constraints From Ligo O3 Data On Gravitational-Wave Emission Due To R-Modes In The Glitching Pulsar Psr J0537-6910, R. Abbott, T. D. Abbott

Faculty Publications

We present a search for continuous gravitational-wave emission due to r-modes in the pulsar PSR J0537-6910 using data from the LIGO-Virgo Collaboration observing run O3. PSR J0537-6910 is a young energetic X-ray pulsar and is the most frequent glitcher known. The inter-glitch braking index of the pulsar suggests that gravitational-wave emission due to r-mode oscillations may play an important role in the spin evolution of this pulsar. Theoretical models confirm this possibility and predict emission at a level that can be probed by ground-based detectors. In order to explore this scenario, we search for r-mode emission in the epochs between …

The Solar Memory From Hours To Decades, Markus J. Aschwanden, Jay R. Johnson

Faculty Publications

Waiting-time distributions allow us to distinguish at least three different types of dynamical systems, including (i) linear random processes (with no memory); (ii) nonlinear, avalanche-type, nonstationary Poisson processes (with memory during the exponential growth of the avalanche rise time); and (iii) chaotic systems in the state of a nonlinear limit cycle (with memory during the oscillatory phase). We describe the temporal evolution of the flare rate λ(t) ∝ t p with a polynomial function, which allows us to distinguish linear (p ≈ 1) from nonlinear (p  2) events. The power-law slopes α of the observed waiting times (with full …

Spatiotemporal Non-Uniformly Correlated Beams, Milo W. Hyde Iv

Faculty Publications

We present a new partially coherent source with spatiotemporal coupling. The stochastic light, which we call a spatiotemporal (ST) non-uniformly correlated (NUC) beam, combines space and time in an inhomogeneous (shift- or space-variant) correlation function. This results in a source that self-focuses at a controllable location in space-time, making these beams potentially useful in applications such as optical trapping, optical tweezing, and particle manipulation. We begin by developing the mutual coherence function for an ST NUC beam. We then examine its free-space propagation characteristics by deriving an expression for the mean intensity at any plane z ≥ 0. To validate …

Uncertainty Analysis For Ccd-Augmented Casi® Brdf Measurement System, Todd V. Small, Samuel D. Butler, Michael A. Marciniak

Faculty Publications

This work presents a measurement uncertainty analysis for a system designed to simultaneously capture specular in-plane and out-of-plane bidirectional reflectance distribution function (BRDF) data with high spatial resolution by augmenting the Complete Angle Scatter Instrument (CASI®) with a charge-coupled device (CCD) camera. Various scatter flux, incident flux, scatter angle, and detector solid angle uncertainty contributions are considered and evaluated based on imperfectly known system parameters. In particular, incident flux temporal fluctuation, detector noise and non-linearity, and out-of-plane aperture misalignment considerations each require significant adjustment from original CASI® uncertainty analysis, and expressions for neutral density (ND) filter, scatter angle, and solid …

Traffic Collision Avoidance System: False Injection Viability, John Hannah, Robert F. Mills, Richard A. Dill, Douglas D. Hodson

Faculty Publications

Safety is a simple concept but an abstract task, specifically with aircraft. One critical safety system, the Traffic Collision Avoidance System II (TCAS), protects against mid-air collisions by predicting the course of other aircraft, determining the possibility of collision, and issuing a resolution advisory for avoidance. Previous research to identify vulnerabilities associated with TCAS’s communication processes discovered that a false injection attack presents the most comprehensive risk to veritable trust in TCAS, allowing for a mid-air collision. This research explores the viability of successfully executing a false injection attack against a target aircraft, triggering a resolution advisory. Monetary constraints precluded …

Effects Of Sesame Consumption On Inflammatory Biomarkers In Humans: A Systematic Review And Meta-Analysis Of Randomized Controlled Trials, Shabnam Rafiee, Roghaye Faryabi, Mohammad Ali Zareian, Jessie Hawkins, Nitin Shivappa Mbbs, Mph, Ph.D., Laila Shirbeigi

Faculty Publications

Objectives. Existing evidence produces conflicting findings regarding the effect of sesame intake on inflammatory biomarkers; thisknowledge gap has yet to be met through systematic review and meta-analysis. )is meta-analysis of randomized, controlledclinical trials (RCTs) was conducted to evaluate the effects of sesame consumption on markers of inflammation in humans. Methods. PubMed, Scopus, and the Cochrane Database of Systematic Reviews were searched through August 2020 to identify relevant papers for inclusion. Using the random-effects model, data were evaluated as weighted mean differences (WMD) with 95% confidence intervals (CI). Cochrane’s Q and I-squared (I2) tests were used to …

Searching For Solar Kdar With Dune, The Dune Collaboration, A. Abed Abud, B. Abi, R. Acciarri, M. A. Acero, M. R. Adames, G. Adamov, D. Adams, M. Adinolfi, A. Aduszkiewicz, J. Aguilar, Z. Ahmad, J. Ahmed, B. Ali-Mohammadzadeh, T. Alion, K. Allison, S. Alonso Monsalve, M. Alrashed, C. Alt, A. Alton, Roberto Petti, Et. Al.

Faculty Publications

The observation of 236 MeV muon neutrinos from kaon-decay-at-rest (KDAR) originating in the core of the Sun would provide a unique signature of dark matter annihilation. Since excellent angle and energy reconstruction are necessary to detect this monoenergetic, directional neutrino flux, DUNE with its vast volume and reconstruction capabilities, is a promising candidate for a KDAR neutrino search. In this work, we evaluate the proposed KDAR neutrino search strategies by realistically modeling both neutrino-nucleus interactions and the response of DUNE. We find that, although reconstruction of the neutrino energy and direction is difficult with current techniques in the relevant energy …

All-Sky Search For Continuous Gravitational Waves From Isolated Neutron Stars In The Early O3 Ligo Data, R. Abbott, T. D. Abbott, S. Abraham, F. Acernese, K. Ackley, A. Adams, C. Adams, R. X. Adhikari, V. B. Adya, C. Affeldt, D. Agarwal, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, L. Aiello, A. Ain, P. Ajith, T. Akutsu, Tiffany Z. Summerscales

Faculty Publications

We report on an all-sky search for continuous gravitational waves in the frequency band 20-2000 Hz and with a frequency time derivative in the range of [-1.0,+0.1]×10-8 Hz/s. Such a signal could be produced by a nearby, spinning and slightly nonaxisymmetric isolated neutron star in our Galaxy. This search uses the LIGO data from the first six months of Advanced LIGO's and Advanced Virgo's third observational run, O3. No periodic gravitational wave signals are observed, and 95% confidence-level (C.L.) frequentist upper limits are placed on their strengths. The lowest upper limits on worst-case (linearly polarized) strain amplitude h0 are ∼1.7×10-25 …

Diffusional Fractionation Of Helium Isotopes In Silicate Melts, Haiyang Luo, Bijaya Karki, Dipta B. Ghosh, Huiming Bao

Faculty Publications

Estimating Helium (He) concentration and isotope composition of the mantle requires quantifying He loss during magma degassing. The knowledge of diffusional He isotope fractionation in silicate melts may be essential to constrain the He loss. Isotopic mass dependence of He diffusion can be empirically expressed as D3He/D4He = (4/3)^β, where D is the diffusivity of a He isotope. However, no studies have reported any β values for He in silicate melts due to technical challenges in both experiments and computations. Here, molecular dynamics simulations based on deep neural network potentials trained by ab initio data …

Determining Diagnosis Date Of Diabetes Using Structured Electronic Health Record (Ehr) Data: The Search For Diabetes In Youth Study, Kristin M. Lenoir, Lynne E. Wagenknecht, Jasmin Divers, Ramon Casanova, Dana Dabelea, Sharon Saydah, Catherine Pihoker, Angela D. Liese Ph.D., Debra Standiford, Richard Hamman, Brian J. Wells, The Search For Diabetes In Youth Study Group

Faculty Publications

Background Disease surveillance of diabetes among youth has relied mainly upon manual chart review. However, increasingly available structured electronic health record (EHR) data have been shown to yield accurate determinations of diabetes status and type. Validated algorithms to determine date of diabetes diagnosis are lacking. The objective of this work is to validate two EHR-based algorithms to determine date of diagnosis of diabetes. Methods A rule-based ICD-10 algorithm identified youth with diabetes from structured EHR data over the period of 2009 through 2017 within three children’s hospitals that participate in the SEARCH for Diabetes in Youth Study: Cincinnati Children’s Hospital, …

New Approach For Assigning Mean Oxidation Number Of Carbons To Organonitrogen And Organosulfur Compounds, Pong Kau Yuen, Cheng Man Diana Lau

Faculty Publications

Organonitrogen and organosulfur compounds are abundant in the natural environment. To understand the biological redox pathways properly, it is important for learners to be able to count the oxidation number of organic carbons. However, the process of counting is not always easy. In addition, organonitrogen and organosulfur molecules are seldom studied. To compensate these problems, this paper explores the bonddividing method, which can effectively determine the mean oxidation number of carbons of organonitrogen and organosulfur molecules. This method uses the cleavage of carbon-sulfur and carbon-nitrogen bonds to obtain the organic and inorganic fragments. The mean oxidation numbers of carbon atoms, …

All-Sky Search For Continuous Gravitational Waves From Isolated Neutron Stars In The Early O3 Ligo Data, Ligo Scientific Collaboration, Virgo Collaboration, Kagra Collaboration, Tiffany Z. Summerscales

Faculty Publications

We report on an all-sky search for continuous gravitational waves in the frequency band 20–2000 Hz and with a frequency time derivative in the range of [−1.0,+0.1]×10−8  Hz/s. Such a signal could be produced by a nearby, spinning and slightly nonaxisymmetric isolated neutron star in our Galaxy. This search uses the LIGO data from the first six months of Advanced LIGO’s and Advanced Virgo’s third observational run, O3. No periodic gravitational wave signals are observed, and 95% confidence-level (C.L.) frequentist upper limits are placed on their strengths. The lowest upper limits on worst-case (linearly polarized) strain amplitude h0 are ∼1.7×10−25 …