Physical Sciences and Mathematics Commons^™

Identification And Characterization Of A New Tubulin-Binding, Susan L. Mooberry, Kimberly N. Weiderhold, Sivanesan Dakshanamurthy, Ernest Hamel, Edith J. Banner, Anastasia Kharlamova, Jonathan Hempel, John T. Gupton, Milton L. Brown

Chemistry Faculty Publications

We studied the mechanism of action of 3,5-dibromo-4-(3,4-dimethoxyphenyl)-1H-pyrrole-2-carboxylic acid ethyl ester (JG-03-14) and found that it is a potent microtubule depolymerizer. JG-03-14 caused a dose-dependent loss of cellular microtubules, formation of aberrant mitotic spindles, accumulation of cells in the G₂/M phase of the cell cycle, and Bcl-2 phosphorylation. These events culminated in the initiation of apoptosis, as evidenced by the caspase 3-dependent cleavage of poly(ADP-ribose) polymerase (PARP). JG-03-14 has antiproliferative activity against a wide range of cancer cell lines, with an average IC₅₀ value of 62 nM, and it is a poor substrate for transport …

Augmentation In Visual Reality (Avr), Yunjun Zhang

Electronic Theses and Dissertations

Human eyes, as the organs for sensing light and processing visual information, enable us to see the real world. Though invaluable, they give us no way to "edit" the received visual stream or to "switch" to a different channel. The invention of motion pictures and computer technologies in the last century enables us to add an extra layer of modifications between the real world and our eyes. There are two major approaches to modifications that we consider here, offline augmentation and online augmentation. The movie industry has pushed offline augmentation to an extreme level; audiences can experience visual surprises that …

Euchoreutes Naso Sclater, 1890: Ein Säugetier-Endemit Zentralasiens, Annegret Stubbe, Michael Stubbe, Nyamsuren Batsaikhan, Ravčigijn Samjaa, Ellen Driechciarz, René Driechciarz, A. Schonert, M. Winter

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

The first specimen of Euchoreutes naso was collected by N. M. PRZEWALSKI 1879 in Central Asia, in Dzungaria. SCLATER described the species in 1890. In Mongolia Euchoreutes was found in 1924. Fifty years later new records were published by SOKOLOV et al. (1978). A taxonomic revision was done by ŠENBROT et al. (1992, 1995). The species was related to the family Sminthidae (Rodentia/Mammalia). We found the most eastern locality in Mongolia at the longitude 106° 47' E. The reproduction rate was 3.1 (n = 8 females). In the laboratory we noticed a litter of four young. The body mass …

Feeding Ecology Of Asiatic Wild Ass Equus Hemionus, Jochen Lengger, Frieda Tataruch, Christian Walzer

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

The Mongolian wild ass or khulan (Equus hemionus) is a potential competitor for forage to reintroduced Przewalski’s horses. To evaluate the major foraging plants of khulan we chose the alkane method that was first described by Mayes in 1984. Different plant species contain varying amounts and proportions of n-alkanes. This fact allows the determination of diet composition by comparing the plant alkane to the fecal alkane pattern. The major advantage is that the method is non-invasive and has been shown to be a reliable method in captive trials. Fecal and plant samples were collected simultaneously and preserved by …

Social Networks In Wild Asses: Comparing Patterns And Processes Among Populations, Daniel I. Rubenstein, Siva Sundaresan, Ilya Fischhoff, David Saltz

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

Asiatic wild asses inhabit some of the most arid environments in the world. All live in fissionfusion societies, but demography varies and the deserts in which they live often differ in subtle ways. Characterizing details of social structure of wild ass populations has been a challenge and has made it difficult to determine causes and consequences of any differences that might exist. We use network theory to compare the social structures of two populations of Asiatic asses/ onagers inhabiting the Negev desert, Israel and khur of the Little Rann of Kuch, India and show that populations differ in important structural …

An Overview On The State Of Equus Hemionus In Whole China, Weikang Yang

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

The wild ass in China is divided into two species: Gobi khulan (Equus hemionus) and kiang (Equus kiang). Maps and charts of the distribution and population sizes in China and Mongolia of each species are shown from the 1980s through the early 2000s.

Social Organization And Determinants Of Spatial Distribution Of Khur (Equus Hemionus Khur), Nita Shah, Qamar Qureshi

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

Khur (Equus hemionus khur) is an endangered species for the most part restricted in little Rann of Kutch (India) and surrounding areas. We investigated factors influencing spatial distribution and social organization of khur. The spatial distribution is largely influenced by distribution of food patches and water in this ecosystem. The inter group distances were smaller in resource rich areas in comparison to resource poor areas (p = 0.017). The group sizes are larger in areas having higher productivity (r = 0.85) and rainfall (r = 0.88). Four social units are observed in khur (a) Family …

Numbers, Distribution And Social Structure Of Kiang (Equus Kiang Moorcroft 1841) Population In The Southwestern Part Of Tibet, China, Natalia V. Paklina, Chris Van Orden

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

In September - October 1998 we made an extensive survey in southwest Tibet to study numbers, distribution and social structure of the kiang population in this remote part of its range. Kiangs were sighted between 29º 40’ and 32º 50’ N, and 81º- 86º E. They preferred broad flat valleys with lakes at an altitude from 4,000 up to 5,000 m. Small kiang groups and solitary animals were sighted in Transhimalaya. There were no kiangs in Tsangpo (Brahmaputra) River valley, in the sand desert near Ali and in the Clay Mountains near Tsada. Seven old kiang corpses were found along …

The Birth Of A Wild Ass (Equus Hemionus Khur) In India’S Little Rann Of Kutch, Gertrud Neumann-Denzau

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

The birth of a wild ass was completely described and photographed in the wild for the first time. It happened in the daytime, in the open desert, and in the vicinity of other wild asses. The mother isolated her foal afterwards for an entire day. After birthing she drove away her male yearling, which did not join her any longer from this moment on.

Biodiversity In Space And Time: Towards A Grid Mapping For Mongolia, Michael Stubbe, Annegret Stubbe, Henrik Von Wehrden, Nayamsuren Batsaikhan, Ravčigijn Samjaa

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

In the future, grid mapping of animal and plant organisms will also play a major role in Mongolia. Based on geographical coordinates, a grid with a resolution of 100 x 100 km was created, which contained 561 cells. Methods and level of current understanding are exemplified by means of two raptors and three mammal species. This establishes a basis for an initial project, which will summarize all breeding occurrences of raptors based on all records, publications, or diary notes. For the first time, the short toed eagle was verified in Mongolia as a breeding bird in 2004. By 2006, ten …

Zum Vorkommen Ausgewählter Bembidion-Arten In Der Mongolei (Coleoptera: Carabidae, Bembidiinae): 2. Beitrag Zur Carabidenfauna Der Mongolei, Peer Haro Schnitter

Erforschung biologischer Ressourcen der Mongolei / Exploration into the Biological Resources of Mongolia, ISSN 0440-1298

To the occurrence of some Bembidion-species in Mongolia (Coleoptera: Carabidae, Bembidiinae) - Second contribution to the carabid fauna of Mongolia.

The distribution of four Bembidion-species, Bembidion (Asioperyphus) infuscatum DEJEAN, 1831, B. (Asioperyphus) ovale MOTSCHULSKY, 1844, B. (Bracteon) conicolle MOTSCHULSKY, 1844 und B. (Bracteon) lapponicum ZETTERSTEDT, 1828, in Mongolia are discussed, and new data are given.

Intramolecular Chemistry Of Ss-Acetoxyethylidene And Photochemical Generation Of Vinylidenes, Jennifer M. Nguyen

Honors Theses

The parent carbene ß-acetoxyethylidene has been previously generated by the photolysis of its precursor, acetic acid 1a,9b-dihydro-1H-cyclopropa[l]phenanthren-1-yl methyl ester. Mechanistic studies on ß-acetoxyethylidene have indicated the possibilities of three rearrangement pathways to the formation of vinyl acetate: a proton shift, an acyl shift, and a cyclic rearrangement (see Figure 8). A deuterium labeling study involving the replacement of the hydrogens on the methylene carbon has indicated that the simple 1,2-H shift was the primary manner of rearrangement, with an 82% yield of product. However, a primary kinetic isotope effect may have occurred due to the greater strength of a C-D …

World Bank -Cpa Conflict: The Struggle To Define Human Rights And Development In The Philippines, Adam B. Robbins

Honors Theses

This thesis analyzes the interactions between the World Bank (hereafter, the Bank) and the Cordillera Peoples Alliance (CPA), an indigenous and environmental advocacy group based in the Cordillera region of Luzon, in the Philippines. Using data gathered through both text-based and participatory research methods, I analyze the discursive relationship and violent confrontations between the two organizations. Conflicting development and human rights values cause the majority of these conflicts. I focus on how each organization enacts development and human rights, and how this leads to conflict. Ultimately, I intend for this thesis to offer practical guidance for the reader involved in …

Developing A Tool To Assess Human Health Impacts Of Purchasing, Kaitlin C. Himmelmann

Honors Theses

Chemical production impacts the environment and human health. Many common products contain chemicals that can be detrimental to human health and more specifically harmful to the endocrine system. Many individuals and institutions unknowingly buy products containing chemicals that can harm the endocrine system. I developed a score that examines the level of harm that these chemicals pose to the endocrine health of the general population. The implications of Colby’s purchasing practices are discussed.

Detailed Mechanistic And Optimization Of The Photochemical Production Method Of Superoxide, Ta-Chung Ong

Honors Theses

The highly reactive nature of superoxide anion presents an analytical challenge to prepare stable standards for instrument calibration. McDowell et al. (1983) developed a convenient method of superoxide production based on continuous photolysis of benzophenone and acetone in oxygen saturated, alkaline, 2-propanol solution. In the McDowell reaction, ketones are photolyzed to their triplet state, and then reacted with alcohol to produce ketyl radicals that react with oxygen to produce superoxide. This study investigated the mechanism and rate of these reactions by Laser Flash Photolysis (LFP). Reaction rate constants for the reaction between the benzophenone triplet and ethanol was 5.5 x …

Gauguin : Generating Art Using Genetic Algorithms & User Input Naturally, Thomas E. Cook

Honors Theses

This paper outlines an undergraduate research project demonstrating an application of evolutionary computation in the context of computer art. The project, named GAUGUIN, combines the visual impact of modern computer graphics with the computational power of genetic algorithms. GAUGUIN allows the user to become a creator of art, without requiring any technical or artistic training. By using an intuitive and easily comprehensible process like evolution to create the composition, the user simply needs to evaluate a sequence of compositions. Mimicking the biological process of evolution, the system will evolve the works in order to achieve images that are more visually …

Concomitant Polymorphism In 1,2-Bis(9-Anthryl)Acetylene, Rebecca Goldstein

Honors Theses

This thesis details the serendipitous discovery of the phenomenon of concomitant conformational polymorphism found to exist in 1,2-bis(9-anthryl)acerylene. 1,2-bis(9anthryl)acetylene is a previously published molecule. However, the published crystal structure showed the molecule to be completely planar, and to crystallize in the form of orange needles. While this form of the crystal was indeed found during the synthesis of 1,2-bis(9anthryl)acetylene, a new polymorph, crystallizing as yellow prisms, was also discovered. This yellow polymorph was found by X-ray crystallography to be monoclinic with an angle of 66.7 between the anthracene planes. The planar polymorph 1,2-bis(9-anthryl)acetylene was also found by X-ray crystallography to …

Soils: A Contemporary Perspective, Cheryl Palm, Pedro Sanchez, Sonya Ahamed, Alex Awiti

East Africa Institute

Soils are viewed in the context of ecosystem services, soil processes and properties, and key attributes and constraints. The framework used is based on the premise that the natural capital of soils that underlies ecosystem services is primarily determined by three core soil properties: texture, mineralogy, and soil organic matter. Up-to-date descriptions and geographical distribution of soil orders as well as soil attributes and constraints are given, along with the relationships between soil orders, properties, and biomes. We then relate ecosystem services to specific soil processes, soil properties, and soil constraints and attributes. Soil degradation at present is not adequately …

Bridges And Barriers To Developing And Conducting Interdisciplinary Graduate-Student Team Research, Max Nielsen-Pincus, Wayde Cameron Morse, Jo Ellen Force, J. D. Wulfhorst

Environmental Science and Management Faculty Publications and Presentations

Understanding complex socio-environmental problems requires specialists from multiple disciplines to integrate research efforts. Programs such as the National Science Foundation’s Integrative Graduate Education and Research Traineeship facilitate integrated research efforts and change the way academic institutions train future leaders and scientists. The University of Idaho and the Tropical Agricultural Research and Higher Education Center in Costa Rica collaborate on a joint research program focusing on biodiversity conservation and sustainable production in fragmented landscapes. We first present a spectrum of integration ranging from disciplinary to transdisciplinary across seven aspects of the research process. We then describe our experiences and lessons learned …

Estimating Nutrient Uptake By Mature Tree Roots Under Field Conditions: Challenges And Opportunities, Melissa S. Lucash, Dave M. Eissenstat, J. Devereux Joslin, Karis J. Mcfarlane, Ruth D. Yanai

Environmental Science and Management Faculty Publications and Presentations

Nutrient uptake by roots of mature trees is difficult to measure accurately under field conditions using existing methods. In this review, we discuss current techniques for measuring uptake at the root surface including excised roots, isotopic tracers, autoradiography, depletion, and lysimeters. Although these methods have provided many insights, each has drawbacks. Estimates of uptake are affected by the sampling scheme, experimental conditions, whether roots are excised or not, concentrations of ions, and the rate of efflux of ions. Microbes and mycorrhizas can also affect estimates of uptake. A greater focus on methods development is critical to advancing our understanding of …

Observational Intelligence: An Overview Of Computational Actual Entities And Their Use As Agents Of Artificial Intelligence, Brandon Scot Saunders

Theses and Dissertations

This thesis' focus is on the use of Alfred North Whitehead's concept of Actual Entities as a computational tool for computer science and the introduction of a novel usage of Actual Entities as learning agents. Actual Entities are vector based agents that interact within their environment through a process called prehension. It is the combined effect of multiple Actual Entities working within a Colony of Prehending Entities that produces emergent, intelligent behavior. It is not always the case that prehension functions for desired behavior are known beforehand and frequently the functions are too complex to construct by hand. Through the …

Supporting Data-Intensive Wireless Sensor Applications Using Smart Data Fragmentation And Buffer Management, Mbonisi Masilela

Theses and Dissertations

Recent advances in low power device technology have led to the development of smaller powerful sensors geared for use in Wireless Sensor Networks. Some of these sensors are capable of producing large data packets in a single reading. This becomes a challenging problem given the constraints imposed by current MAC and Transport Layer implementations since a single data packet can exceed the MTU of the protocol stack. Little has been done in the way of addressing this issue in Wireless Sensor Networks. This paper proposes a novel solution to this issue. Proposed is a Lightweight Data Transportation Protocol that uses …

Preparation Of Chiral Cholestanofluorene And Its Electron-Rich Derivatives For Isolation Of A Stable Cation−Radical Salt, Paromita Debroy, Ruchi Shukla, Sergey V. Lindeman, Rajendra Rathore

Chemistry Faculty Research and Publications

A simple and practical synthesis of a variety of chiral fluorene derivatives is described where a cholestane moiety is attached to the carbon 9 of the fluorene ring system from readily available starting materials. An appropriately substituted fluorene derivative (i.e., R = OMe) forms a highly colored (chiral) cation−radical that can be isolated as robust hexachloroantimonate salt. Interestingly, the simplest cholestanofluorene (i.e., R = H) can also be transformed into a dibromo derivative (i.e., R = Br), a precursor to the (poly)cholestanofluorenes where the cholestane moieties will serve not only as groups that impart chirality but also allow them to …

Conserved Amino Acids In Each Subunit Of The Heteroligomeric Trna M1A58 Mtase From Saccharomyces Cerevisiae Contribute To Trna Binding, Sarah G. Ozanick, Janusz M. Bujnicki, Daniel S. Sem, James T. Anderson

Chemistry Faculty Research and Publications

In Saccharomyces cerevisiae, a two-subunit methyltransferase (Mtase) encoded by the essential genes TRM6 and TRM61 is responsible for the formation of 1-methyladenosine, a modified nucleoside found at position 58 in tRNA that is critical for the stability of . The crystal structure of the homotetrameric m¹A58 tRNA Mtase from Mycobacterium tuberculosis, TrmI, has been solved and was used as a template to build a model of the yeast m¹A58 tRNA Mtase heterotetramer. We altered amino acids in TRM6 and TRM61 that were predicted to be important for the stability of the heteroligomer based on …

Enhanced Fire Retardancy Of Vinyl Ester Resins By Combination Of Additives, Grace Chigwada, Charles A. Wilkie

Chemistry Faculty Research and Publications

In pursuit of fire-retardant materials, vinyl ester resins were combined with commercially available fire retardants at lower loadings than that at which they are usually effective when used alone. The thermal stability and flammability of the various combinations of fire retardants were evaluated by thermogravimetric analysis and cone calorimetric analysis. With some combinations, the 50% degradation temperature was improved by about 5-10ºC Different additives affected the flammability to varying extents and some combinations resulted in an enhanced fire retardancy compared to the additives used alone. The combinations that showed the best reductions in the peak heat release rate (PHRR) were …

Synthesis Of The Giant Dielectric Constant Material Cacu3ti4o12 By Wet-Chemistry Methods, Jianjun Liu, Robert W. Smith, Wai-Ning Mei

Chemistry Faculty Publications

CaCu3Ti4O12 (CCTO) has a giant dielectric constant of up to 105 at room temperature and great potential for technological application. In this work, we report two wet-chemistry methods to synthesize CCTO at relatively low temperatures and short reaction times. The pure-phase sample was obtained at 800 °C for 0.5 h, and the grain size of a pellet sample sintered at 1030 °C has a homogeneous distribution in the range of 0.4–1.5 μm.

Pov-It: The Pov-Ray Interactive Tutorial, Eleanor O'Rourke

Honors Theses

The Persistence of Vision Ray Tracer, commonly known as POV-Ray, is a computer graphics package that can be used to produce highly sophisticated and photorealistic images and animations. POV-Ray is widely used in the computer graphics community for a diverse variety of applications, including teaching college courses, creating visual music animations, and generating computer art. Although the popularity of POV-Ray is apparent, the teaching materials available for the package are confusing, disorganized, and inaccessible. In this project, I have designed an online system that provides a series of interactive tutorials that teach users how to create images using the POV-Ray …

External Control Of Electron Temperature In Ultra-Cold Plasmas, Roy O. Wilson

Honors Theses

This thesis discusses progress towards achieving external control of the electron temperature and the Coulomb coupling parameter of ultra-cold plasmas. Using a Littman dye laser, we create the plasma by partially photoionizing a dense, cold sample of rubidium atoms in a magneto-optical trap (MOT). At a controllable time delay, we excite neutral atoms in the plasma to a specific Rydberg state using a narrow bandwidth pulsed dye laser. We have made progress towards optimizing and quantifying the achievable Rydberg atom density by using mm-wave spectroscopy to control the evolution of a cold dense Rydberg sample to plasma and have also …

Simulation Of The Recent Multidecadal Increase Of Atlantic Hurricane Activity Using An 18-Km-Grid Regional Model, Thomas R. Knutson, Joseph J. Sirutis, Stephen T. Garner, Isaac M. Held, Robert E. Tuleya

CCPO Publications

In this study, a new modeling framework for simulating Atlantic hurricane activity is introduced. The model is an 18-km-grid nonhydrostatic regional model, run over observed specified SSTs and nudged toward observed time-varying large-scale atmospheric conditions (Atlantic domain wavenumbers 0-2) derived from the National Centers for Environmental Prediction (NCEP) reanalyses. Using this "perfect large-scale model" approach for 27 recent August-October seasons (1980-2006), it is found that the model successfully reproduces the observed multidecadal increase in numbers of Atlantic hurricanes and several other tropical cyclone (TC) indices over this period. The correlation of simulated versus observed hurricane activity by year varies from …

Asteroseismology Of The Pg 1159 Star Pg 0122+200, Jianning Fu, Matt A. Wood

Aerospace, Physics, and Space Science Faculty Publications

Context. The variable pre-white dwarf PG 1159 stars (GW Vir) are g-mode non-radial pulsators. Asteroseismology puts strong constraints on their global parameters and internal structure. PG 0122+200 defines the red edge of the instability strip and its evolutionary timescale is predicted to be dominated by neutrino emission. Its study offers the opportunity to better understand the instability mechanism and to validate the physics of the neutrino production in dense plasma. Aims. To achieve such a goal requires determining precisely its fundamental parameters. This is the goal of this paper. Methods. We present new multi-site photometric observations obtained in 2001 and …