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2010

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Articles 5971 - 6000 of 8625

Full-Text Articles in Physical Sciences and Mathematics

The Acute Nociceptive Signals Induced By Bradykinin In Rat Sensory Neurons Are Mediated By Inhibition Of M-Type K+ Channels And Activation Of Ca2+-Activated Cl- Channels, Boyi Liu, John E. Linley, Xiaona Du, Xuan Zhang, Lezanne Ooi, Hailin Zhang, Nikita Gamper Jan 2010

The Acute Nociceptive Signals Induced By Bradykinin In Rat Sensory Neurons Are Mediated By Inhibition Of M-Type K+ Channels And Activation Of Ca2+-Activated Cl- Channels, Boyi Liu, John E. Linley, Xiaona Du, Xuan Zhang, Lezanne Ooi, Hailin Zhang, Nikita Gamper

Faculty of Science - Papers (Archive)

Bradykinin (BK) is an inflammatory mediator and one of the most potent endogenous pain-inducing substances. When released at sites of tissue damage or inflammation, or applied exogenously, BK produces acute spontaneous pain and causes hyperalgesia (increased sensitivity to potentially painful stimuli). The mechanisms underlying spontaneous pain induced by BK are poorly understood. Here we report that in small nociceptive neurons from rat dorsal root ganglia, BK, acting through its B2 receptors, PLC, and release of calcium from intracellular stores, robustly inhibits M-type K+ channels and opens Ca2+-activated Cl- channels (CaCCs) encoded by Tmem16a (also known as Ano1). Summation of these …


Transcriptional Control Of Kcnq Channel Genes And The Regulation Of Neuronal Excitability, Mariusz Mucha, Lezanne Ooi, John Linley, Pawel Mordaka, Carine Dalle, Brian Robertson, Nikita Gamper, Ian C. Wood Jan 2010

Transcriptional Control Of Kcnq Channel Genes And The Regulation Of Neuronal Excitability, Mariusz Mucha, Lezanne Ooi, John Linley, Pawel Mordaka, Carine Dalle, Brian Robertson, Nikita Gamper, Ian C. Wood

Faculty of Science - Papers (Archive)

Regulation of the resting membrane potential and the repolarization of neurons are important in regulating neuronal excitability. The potassium channel subunits Kv7.2 and Kv7.3 play a key role in stabilizing neuronal activity. Mutations in KCNQ2 and KCNQ3, the genes encoding Kv7.2 and Kv7.3, cause a neonatal form of epilepsy, and activators of these channels have been identified as novel antiepileptics and analgesics. Despite the observations that regulation of these subunits has profound effects on neuronal function, almost nothing is known about the mechanisms responsible for controlling appropriate expression levels. Here we identify two mechanisms responsible for regulating KCNQ2 and …


Chemistry Of Hydrogen Oxide Radicals (Hox) In The Arctic Troposphere In Spring, J Mao, D J. Jacob, M J. Evans, J R. Olson, X Ren, W H. Brune, T M. St. Clair, J D. Crounse, K M. Spencer, M R. Beaver, P O. Wennberg, M J. Cubison, J L. Jimenez, A Fried, P Weibring, J G. Walega, S R. Hall, A J. Weinheimer, R C. Cohen, G Chen, J H. Crawford, C Mcnaughton, A D. Clarke, L Jaegle, Jenny A. Fisher, R M. Yantosca, P Le Sager, C C. Carouge Jan 2010

Chemistry Of Hydrogen Oxide Radicals (Hox) In The Arctic Troposphere In Spring, J Mao, D J. Jacob, M J. Evans, J R. Olson, X Ren, W H. Brune, T M. St. Clair, J D. Crounse, K M. Spencer, M R. Beaver, P O. Wennberg, M J. Cubison, J L. Jimenez, A Fried, P Weibring, J G. Walega, S R. Hall, A J. Weinheimer, R C. Cohen, G Chen, J H. Crawford, C Mcnaughton, A D. Clarke, L Jaegle, Jenny A. Fisher, R M. Yantosca, P Le Sager, C C. Carouge

Faculty of Science - Papers (Archive)

We use observations from the April 2008 NASA ARCTAS aircraft campaign to the North American Arctic, interpreted with a global 3-D chemical transport model (GEOS-Chem), to better understand the sources and cycling of hydrogen oxide radicals (HOx≡H+OH+peroxy radicals) and their reservoirs (HOy≡HOx+peroxides) in the springtime Arctic atmosphere. We find that a standard gas-phase chemical mechanism overestimates the observed HO2 and H2O2 concentrations. Computation of HOx and HOy gas-phase chemical budgets on the basis of the aircraft observations also indicates a large missing sink for both. We hypothesize that …


The Arctic Research Of The Composition Of The Troposphere From Aircraft And Satellites (Arctas) Mission: Design, Execution, And First Results, D J. Jacob, J H. Crawford, H Maring, A D. Clarke, J E. Dibb, L K. Emmons, R A. Ferrare, C A. Hostetler, P B. Russell, H B. Singh, A M. Thompson, G E. Shaw, E Mccauley, J R. Pederson, J A. Fisher Jan 2010

The Arctic Research Of The Composition Of The Troposphere From Aircraft And Satellites (Arctas) Mission: Design, Execution, And First Results, D J. Jacob, J H. Crawford, H Maring, A D. Clarke, J E. Dibb, L K. Emmons, R A. Ferrare, C A. Hostetler, P B. Russell, H B. Singh, A M. Thompson, G E. Shaw, E Mccauley, J R. Pederson, J A. Fisher

Faculty of Science - Papers (Archive)

The NASA Arctic Research of the Composition of the Troposphere from Aircraft and Satellites (ARCTAS) mission was conducted in two 3-week deployments based in Alaska (April 2008) and western Canada (June–July 2008). Its goal was to better understand the factors driving current changes in Arctic atmospheric composition and climate, including (1) influx of mid-latitude pollution, (2) boreal forest fires, (3) aerosol radiative forcing, and (4) chemical processes. The June–July deployment was preceded by one week of flights over California (ARCTAS-CARB) focused on (1) improving state emission inventories for greenhouse gases and aerosols, (2) providing observations to test and improve models …


Putting The Architecting Back Into Software Architecture With Systems Thinking Agent-Based Modelling, Trevor Harrison, Allan Peter Campbell, Thong Nguyen Jan 2010

Putting The Architecting Back Into Software Architecture With Systems Thinking Agent-Based Modelling, Trevor Harrison, Allan Peter Campbell, Thong Nguyen

SMART Infrastructure Facility - Papers

This paper details exploratory research which treats architecting as a system. This human architecting system has a structure composed of decisions, interdependencies amongst decisions, decision making, decision makers and the decision-making environment. Agent-based modelling is used to model the architecting system, and simulation is used to visualise system behaviour over time. The goal is to map legitimate / optimal speed of architectural decision-making to an architecting system behaviour pattern. Knowing the appropriate behaviour pattern of early architecture evolution will provide a mechanism for fine-grained progress tracking of architectural design. Divergence from this behaviour pattern should provide early warning signs of …


A Spatial Agent-Based Model To Explore Scenarios Of Adaptation To Climate Change In An Alpine Tourism Destination, Stefano Balbi, Pascal Perez, Carlo Giupponi Jan 2010

A Spatial Agent-Based Model To Explore Scenarios Of Adaptation To Climate Change In An Alpine Tourism Destination, Stefano Balbi, Pascal Perez, Carlo Giupponi

SMART Infrastructure Facility - Papers

A vast body of literature suggests that the European Alpine region may be one of the most sensitive to climate change impacts. Adaptation to climate change of Alpine socioecosystems is increasingly becoming an issue of interest for the scientific community while the people of the Alps are often unaware of or simply ignore the problem. ClimAlpTour is a European research project of the Alpine Space Programme, bringing together institutions and scholars from all countries of the Alpine arch, in view of dealing with the expected decrease in snow and ice cover, which may lead to a rethinking of tourism development …


Some Complex Systems Engineering Principles, Matthew J. Berryman, Peter Campbell Jan 2010

Some Complex Systems Engineering Principles, Matthew J. Berryman, Peter Campbell

SMART Infrastructure Facility - Papers

Complex adaptive systems can be characterised by many adaptively changing parts, with a large number of interactions, and adaptation at the system level. This body of research can inform the large engineering projects that are characterised by large systems of systems, where interactions to achieve end goals matters, and where designs and the technology of parts in service undergo many adaptive changes. A number of key lessons can be drawn from the complex adaptive systems literature. Firstly, that the use of design patterns, as traditionally applied in software engineering, can also be applied to wider systems engineering and systems integration …


Total Column Co2 Measurements At Darwin, Australia - Site Description And Calibration Against In Situ Aircraft Profiles, Nicholas Deutscher, David Griffith, Glenn Bryant,, Paul Wennberg, G. Toon, Rebecca Washenfelder, Gretchen Keppel-Aleks, Debra Wunch, Yael Yavin, Norton Allen, J. F. Blavier, Rodrigo Jimenez, Bruce Daube, Alfram Bright, Daniel Matross, Steven Wofsy, Sunyoung Park Jan 2010

Total Column Co2 Measurements At Darwin, Australia - Site Description And Calibration Against In Situ Aircraft Profiles, Nicholas Deutscher, David Griffith, Glenn Bryant,, Paul Wennberg, G. Toon, Rebecca Washenfelder, Gretchen Keppel-Aleks, Debra Wunch, Yael Yavin, Norton Allen, J. F. Blavier, Rodrigo Jimenez, Bruce Daube, Alfram Bright, Daniel Matross, Steven Wofsy, Sunyoung Park

Faculty of Science - Papers (Archive)

An automated Fourier Transform Spectroscopic (FTS) solar observatory was established in Darwin, Australia in August 2005. The laboratory is part of the Total Carbon Column Observing Network, and measures atmospheric column abundances of CO2 and O2 and other gases. Measured CO2 columns were calibrated against integrated aircraft profiles obtained during the TWP-ICE campaign in January– February 2006, and show good agreement with calibrations for a similar instrument in Park Falls, Wisconsin. A clearsky low airmass relative precision of 0.1% is demonstrated in the CO2 and O2 retrieved column-averaged volume mixing ratios. The 1% negative bias in the FTS XCO2 relative …


Coping With Chaos: Unpredictable Food Supplies Intensify Torpor Use In An Arid-Zone Marsupial, The Fat-Tailed Dunnart (Sminthopsis Crassicaudata), Adam J. Munn, Pippa Kern, Bronwyn M. Mcallan Jan 2010

Coping With Chaos: Unpredictable Food Supplies Intensify Torpor Use In An Arid-Zone Marsupial, The Fat-Tailed Dunnart (Sminthopsis Crassicaudata), Adam J. Munn, Pippa Kern, Bronwyn M. Mcallan

Faculty of Science - Papers (Archive)

The severity, duration and amplitude of extreme weather events are forecast to intensify with current climate trends, over both long (e.g. seasonal) and short (e.g. daily) time-scales. As such, the predictability of food supplies for many small endotherms is likely to become increasingly important. Numerous small mammals and birds combat food shortages using torpor, a controlled reduction in metabolic rate and body temperature that helps lower their daily energy requirements. As such, torpor often has been cited as a key feature allowing some small endotherms to survive highly unpredictable climates, such as tropics or dry deserts, but mensurative demonstrations of …


Effects Of A Shark Repulsion Device On Rocky Reef Fishes: No Shocking Outcomes, Alison Broad, N. A. Knott, X. Turon, Andrew R. Davis Jan 2010

Effects Of A Shark Repulsion Device On Rocky Reef Fishes: No Shocking Outcomes, Alison Broad, N. A. Knott, X. Turon, Andrew R. Davis

Faculty of Science - Papers (Archive)

Shark repulsion devices (SRDs; e.g. Shark Shield™) use an electric field to deter large and potentially dangerous sharks. The use of these devices is becoming increasingly widespread for a range of recreational activities as well as scientific and commercial diving. We sought to determine if SRDs might modify the behaviour of chondrichthyan and osteichthyan fishes and thereby impact on fish assemblages, as well as potentially bias diver census techniques. To assess the potential impacts of this technology, we attached SRDs to baited remote underwater video (BRUV) units and deployed them on shallow rocky reefs in Jervis Bay Marine Park (New …


One In Four Citations In Marine Biology Papers Is Inappropriate, Peter Todd, James Guest, Jinzhen Lu, Loke Ming Chou Jan 2010

One In Four Citations In Marine Biology Papers Is Inappropriate, Peter Todd, James Guest, Jinzhen Lu, Loke Ming Chou

Faculty of Science - Papers (Archive)

Citing sources that do not support the assertion being made can misinform readers, perpetuate mistakes and deny credit to the researchers who should have been acknowledged. To quantify citation fidelity in marine biology, we retrieved 198 papers from 2 recent issues of 33 marine biology journals. From each paper we randomly selected 1 citation, recovered the source material, and evaluated its appropriateness. We discovered that the assertion was ‘clearly supported’ by the citation in only 75.8% of cases, the support was ‘ambiguous’ in 10.6% of cases and the citation offered ‘no support’ to the original statement in 6.0% of cases. …


Supply-Side Biogeography: Geographic Patterns Of Settlement And Early Mortality For A Barnacle Approaching Its Range Limit, Justin A. Lathlean, David J. Ayre, Todd E. Minchinton Jan 2010

Supply-Side Biogeography: Geographic Patterns Of Settlement And Early Mortality For A Barnacle Approaching Its Range Limit, Justin A. Lathlean, David J. Ayre, Todd E. Minchinton

Faculty of Science - Papers (Archive)

Species range limits are often associated with reduced adult densities, and this may reflect the failure of a particular life-history stage. For benthic marine invertebrates, settlement is a time of great mortality that strongly influences adult population structure, at least at local spatial scales. In south-eastern Australia we determined that adult abundance of the intertidal barnacle Tesseropora rosea declines over a 450 km region of rocky shore from the middle to the southern limit of its range, and we tested the hypothesis that this biogeographic pattern reflects variations in the production, settlement, or early post-settlement mortality of larvae or adult …


Panmictic Population Structure In The Migratory Marine Sparid Acanthopagrus Australis Despite Its Close Association With Estuaries, David Roberts, David Ayre Jan 2010

Panmictic Population Structure In The Migratory Marine Sparid Acanthopagrus Australis Despite Its Close Association With Estuaries, David Roberts, David Ayre

Faculty of Science - Papers (Archive)

Recent studies have revealed surprising levels of genetic structuring within populations of marine species that were previously thought to be widely dispersed. Such subdivision may reflect unexpected physical or biological barriers to dispersal, including philopatric behaviour. Here we investigate the genetic structure of the eastern Australian yellowfin bream Acanthopagrus australis—a widely distributed species that is thought to be highly dispersive but is also known to spawn in close association with estuaries. Our data from surveys of allele frequencies at 6 microsatellite DNA loci for 350 fish revealed high levels of genetic diversity within all sites but no genetic differentiation of …


Quantifying Wave Exposure In Shallow Temperate Reef Systems: Applicability Of Fetch Models For Predicting Algal Biodiversity, Nicole A. Hill, Austen R. Pepper, Marjetta Puotinen, Michael G. Hughes, Graham J. Edgar, Neville S. Barrett, Rick D. Stuart-Smith, Rebecca Leaper Jan 2010

Quantifying Wave Exposure In Shallow Temperate Reef Systems: Applicability Of Fetch Models For Predicting Algal Biodiversity, Nicole A. Hill, Austen R. Pepper, Marjetta Puotinen, Michael G. Hughes, Graham J. Edgar, Neville S. Barrett, Rick D. Stuart-Smith, Rebecca Leaper

Faculty of Science - Papers (Archive)

Management and conservation of ecosystems relies on biodiversity data; however, broad-scale biological data are often limited. Predictive modelling using environmental variables has recently proven a valuable tool in addressing this gap. Wave exposure is a particularly important environmental variable that structures shallow reef systems, but it is rarely quantified across the large areas often used for predictive studies. Therefore, we investigated approaches that quantify exposure and can be readily applied across a large area. We generated 6 quantitative indices that emphasise different aspects of exposure using a numerical wave model and cartographic fetch models. The utility of these indices for …


Recalcitrant Industrial Wastewater Treatment By Membrane Bioreactor (Mbr), Faisal I. Hai, Kazuo Yamamoto, Fumiyuki Nakajima, Kensuke Fukushi Jan 2010

Recalcitrant Industrial Wastewater Treatment By Membrane Bioreactor (Mbr), Faisal I. Hai, Kazuo Yamamoto, Fumiyuki Nakajima, Kensuke Fukushi

Faculty of Science - Papers (Archive)

Membrane Bioreactor (MBR) process consists of a biological reactor integrated with membranes that combine clarification and filtration of an activated sludge process into a simplified, single step process. The membrane is an absolute barrier to suspended matter and microorganisms and it offers the possibility of operating the system at high mixed liquor suspended solids (MLSS) concentration. The implication of maintenance of high MLSS are— requirement of a smaller footprint and operation at high solids retention time (SRT) under low F/M ratio, hence, yielding reduced excess sludge. Operating as an MBR allows conventional activated sludge plants to become single step processes, …


Fast Digital Optical Flow Estimation Based On Emd, Mickael Quelin, Abdesselam Bouzerdoum, Son Lam Phung Jan 2010

Fast Digital Optical Flow Estimation Based On Emd, Mickael Quelin, Abdesselam Bouzerdoum, Son Lam Phung

Faculty of Informatics - Papers (Archive)

This paper presents an optical flow estimation technique based on the so called Elementary Motion Detector (EMD). The aim is to provide a fast but not necessarily very accurate system to be used for specific post processing purposes. This model uses a low complexity algorithm for detecting motion in four directions by identifying specific motion templates. By extending the motion templates to different scales of the input video, an Elementary Velocity Detector (EVD) is created. This one can save computation time by estimating different speeds in parallel. Information from the EVD outputs is then used to generate an estimate of …


Feature Selection For Facial Expression Recognition, Abdesselam Bouzerdoum, Son Lam Phung, Fok Hing Chi Tivive, Peiyao Li Jan 2010

Feature Selection For Facial Expression Recognition, Abdesselam Bouzerdoum, Son Lam Phung, Fok Hing Chi Tivive, Peiyao Li

Faculty of Informatics - Papers (Archive)

In daily interactions, humans convey their emotions through facial expression and other means. There are several facial expressions that reflect distinctive psychological activities such as happiness, surprise or anger. Accurate recognition of these activities via facial image analysis will play a vital role in natural human-computer interfaces, robotics and mimetic games. This paper focuses on the extraction and selection of salient features for facial expression recognition. We introduce a cascade of fixed filters and trainable non-linear 2-D filters, which are based on the biological mechanism of shunting inhibition. The fixed filters are used to extract primitive features, whereas the adaptive …


Automatic Parameter Selection For Feature-Enhanced Radar Image Restoration, Moeness G Amin, Cher Hau Seng, Son Lam Phung, Abdesselam Bouzerdoum Jan 2010

Automatic Parameter Selection For Feature-Enhanced Radar Image Restoration, Moeness G Amin, Cher Hau Seng, Son Lam Phung, Abdesselam Bouzerdoum

Faculty of Informatics - Papers (Archive)

In this paper, we propose a new technique for optimum parameter selection in non-quadratic radar image restoration. Although both the regularization hyper-parameter and the norm value are influential factors in the characteristics of the formed restoration, most existing optimization methods either require memory intensive computation or prior knowledge of the noise. Here, we present a contrast measure-based method for automated hyper-parameter selection. The proposed method is then extended to optimize the norm value used in non-quadratic image formation and restoration. The proposed method is evaluated on the MSTAR public target database and compared to the GCV method. Experimental results show …


Bridging Micro And Macro Through Experimental Information Acceleration, Tim R. Coltman, Pierre Richard Jan 2010

Bridging Micro And Macro Through Experimental Information Acceleration, Tim R. Coltman, Pierre Richard

Faculty of Informatics - Papers (Archive)

Among leading organizations in all sectors there is evidence that successful managers possess the capability to deal with contradictory tensions within their “macro” competitive and institutional environments. Furthermore, the strategic thinking and decision-making capabilities expected of managers highlight the importance of “micro” processes within organizations. Although macro and micro perspectives are intuitively linked, the empirical literature often separates these two perspectives into either strategy content or process. This paper demonstrates how an experimental method based on “discrete choice analysis” and “information acceleration” can be used to bridge the divide between “micro” managerial processes and the “macro” environmental contexts framing them. …


On Circulant And Two-Circulant Weighing Matrices, K T. Arasu, Ilias S. Kotsireas, Christos Koukouvinos, Jennifer Seberry Jan 2010

On Circulant And Two-Circulant Weighing Matrices, K T. Arasu, Ilias S. Kotsireas, Christos Koukouvinos, Jennifer Seberry

Faculty of Informatics - Papers (Archive)

We employ theoretical and computational techniques to construct new weighing matrices constructed from two circulants. In particular, we construct W(148, 144), W(152, 144), W(156, 144) which are listed as open in the second edition of the Handbook of Combinatorial Designs. We also fill a missing entry in Strassler’s table with answer “YES”, by constructing a circulant weighing matrix of order 142 with weight 100.


Macro-Economic Equilibrium And Price Signal Accuracy In Non-Scalar Economy, Farzad Safaei Jan 2010

Macro-Economic Equilibrium And Price Signal Accuracy In Non-Scalar Economy, Farzad Safaei

Faculty of Informatics - Papers (Archive)

The management of global commons is of vital importance for modern society. The current solutions attempt to internalize the cost of appropriation of commons by adding this to the cost of private resources. In this paper we will show that this approach has some fundamental weaknesses. To overcome these shortcomings, we have proposed to segregate the management of private and shared resources by using non-scalar numbers for the underlying economic signals of money and price. We prove that the resulting non-scalar economy always reaches a macro-economic equilibrium point where the level of appropriation of commons by the society remains steady. …


A Compressive Sensing Approach To Image Restoration, Matthew Kitchener, Abdesselam Bouzerdoum, Son Lam Phung Jan 2010

A Compressive Sensing Approach To Image Restoration, Matthew Kitchener, Abdesselam Bouzerdoum, Son Lam Phung

Faculty of Informatics - Papers (Archive)

In this paper the image restoration problem is solved using a Compressive Sensing approach, and the translation invariant, a Trous, undecimated wavelet transform. The problem is cast as an unconstrained optimization problem which is solved using the Fletcher-Reeves nonlinear conjugate gradient method. A comparison based on experimental results shows that the proposed method achieves comparable if not better performance as other state-of-the-art techniques.


Fuzzy Logic-Based Image Fusion For Multi-View Through-The-Wall Radar, Cher Hau Seng, Abdesselam Bouzerdoum, Fok Hing Chi Tivive, Moeness G. Amin Jan 2010

Fuzzy Logic-Based Image Fusion For Multi-View Through-The-Wall Radar, Cher Hau Seng, Abdesselam Bouzerdoum, Fok Hing Chi Tivive, Moeness G. Amin

Faculty of Informatics - Papers (Archive)

In this paper, we propose a new technique for image fusion in multi-view through-the-wall radar imaging system. As most existing image fusion methods for through-the-wall radar imaging only consider a global fusion operator, it is desirable to consider the differences between each pixel using a local operator. Here, we present a fuzzy logic-based method for pixel-wise image fusion. The performance of the proposed method is evaluated on both simulated and real data from through-the-wall radar imaging system. Experimental results show that the proposed method yields improved performance, compared to existing methods.


Aperiodicity And Cofinality For Finitely Aligned Higher-Rank Graphs, Peter Lewin, Aidan Sims Jan 2010

Aperiodicity And Cofinality For Finitely Aligned Higher-Rank Graphs, Peter Lewin, Aidan Sims

Faculty of Informatics - Papers (Archive)

We introduce new formulations of aperiodicity and cofinality for finitely aligned higher-rank graphs $\Lambda$, and prove that $C^*(\Lambda)$ is simple if and only if $\Lambda$ is aperiodic and cofinal. The main advantage of our versions of aperiodicity and cofinality over existing ones is that ours are stated in terms of finite paths. To prove our main result, we first characterise each of aperiodicity and cofinality of $\Lambda$ in terms of the ideal structure of $C^*(\Lambda)$. In an appendix we show how our new cofinality condition simplifies in a number of special cases which have been treated previously in the literature; …


A Direct Approach To Co-Universal Algebras Associated To Directed Graphs, Aidan Sims, S B. Webster Jan 2010

A Direct Approach To Co-Universal Algebras Associated To Directed Graphs, Aidan Sims, S B. Webster

Faculty of Informatics - Papers (Archive)

We prove directly that if $E$ is a directed graph in which every cycle has an entrance, then there exists a $C^*$-algebra which is co-universal for Toeplitz-Cuntz-Krieger $E$-families. In particular, our proof does not invoke ideal-structure theory for graph algebras, nor does it involve use of the gauge action or its fixed point algebra.


Automatic Classification Of Gpr Signals, W Shao, A Bouzerdoum, S L. Phung, L Su, B Indraratna, C Rujikiatkamjorn Jan 2010

Automatic Classification Of Gpr Signals, W Shao, A Bouzerdoum, S L. Phung, L Su, B Indraratna, C Rujikiatkamjorn

Faculty of Informatics - Papers (Archive)

Ground penetrating radar has been widely used in many areas. However, the processing and interpretation of acquired signals remains a challenging task since it requires experienced users to manage the whole operations. In this paper, we propose an automatic classification system to categorise GPR signals based on magnitude spectrum amplitudes and support vector machines. The system is tested on a real-world GPR data set. The experimental results show that our system can correctly distinguish ground penetrating radar signals reflected by different materials.


Improved Learning In Grid-To-Grid Neural Network Via Clustering, William E. White, Khan M. Iftekharuddin, Abdesselam Bouzerdoum Jan 2010

Improved Learning In Grid-To-Grid Neural Network Via Clustering, William E. White, Khan M. Iftekharuddin, Abdesselam Bouzerdoum

Faculty of Informatics - Papers (Archive)

The maze traversal problem involves finding the shortest distance to the goal from any position in a maze. Such maze solving problems have been an interesting challenge in computational intelligence. Previous work has shown that grid-to-grid neural networks such as the cellular simultaneous recurrent neural network (CSRN) can effectively solve simple maze traversing problems better than other iterative algorithms such as the feedforward multi layer perceptron (MLP). In this work, we investigate improved learning for the CSRN maze solving problem by exploiting relevant information about the maze. We cluster parts of the maze using relevant state information and show an …


Evidence For Specific Subunit Distribution And Interactions In The Quaternary Structure Of Α-Crystallin, Amie M. Morris, J. Andrew Aquilina Jan 2010

Evidence For Specific Subunit Distribution And Interactions In The Quaternary Structure Of Α-Crystallin, Amie M. Morris, J. Andrew Aquilina

Faculty of Science - Papers (Archive)

The quaternary structure of α-crystallin is dynamic, a property which has thwarted crystallographic efforts towards structural characterization. In this study, we have used collision-induced dissociation mass spectrometry to examine the architecture of the polydisperse assemblies of α-crystallin. For total α-crystallin isolated directly from fetal calf lens using size-based chromatography, the αB-crystallin subunit was found to be preferentially dissociated from the oligomers, despite being significantly less abundant overall than the αA-crystallin subunits. Furthermore, upon mixing molar equivalents of purified αA- and αB-crystallin, the levels of their dissociation were found to decrease and increase, respectively, with time. Interestingly though, dissociation of subunits …


Localization Of Low Molecular Weight Crystallin Peptides In The Aging Human Lens Using A Maldi Mass Spectrometry Imaging Approach, S. P. Su, Jason D. Mcarthur, J. A. Aquilina Jan 2010

Localization Of Low Molecular Weight Crystallin Peptides In The Aging Human Lens Using A Maldi Mass Spectrometry Imaging Approach, S. P. Su, Jason D. Mcarthur, J. A. Aquilina

Faculty of Science - Papers (Archive)

Low molecular weight (LMW) peptides, derived from the breakdown of the major eye lens proteins, the crystallins, accumulate in the human lens with age. These LMW peptides are associated with age-related lens opacity and cataract, with some shown to inhibit the chaperone activity of α-crystallin. However, the mechanism(s) giving rise to the production of these peptides, as well as their distribution within the lens, are not well understood. In this study, we have mapped the distribution of these crystallin-derived peptides present in human lenses of different ages using matrix-assisted laser desorption/ionization-imaging mass spectrometry (MALDI-IMS). Our data showed that most of …


And Then There Were None?, Richard G. Roberts, Barry W. Brook Jan 2010

And Then There Were None?, Richard G. Roberts, Barry W. Brook

Faculty of Science - Papers (Archive)

No abstract provided.