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Articles 6001 - 6030 of 8625
Full-Text Articles in Physical Sciences and Mathematics
Effect Of Two Types Of Tree Guards (With And Without Weed Control) On Tree Seedling Establishment, Brenton Ladd, Stephen P. Bonser, Joshua R. Larsen
Effect Of Two Types Of Tree Guards (With And Without Weed Control) On Tree Seedling Establishment, Brenton Ladd, Stephen P. Bonser, Joshua R. Larsen
Faculty of Science - Papers (Archive)
No abstract provided.
Age And Origin Of Alluvial Sediments Within And Flanking The Mt Lofty Ranges, Southern South Australia: A Late Quaternary Archive Of Climate And Environmental Change, D Banerjee, N F. Alley, R P. Bourman, S Buckman, J R. Prescott
Age And Origin Of Alluvial Sediments Within And Flanking The Mt Lofty Ranges, Southern South Australia: A Late Quaternary Archive Of Climate And Environmental Change, D Banerjee, N F. Alley, R P. Bourman, S Buckman, J R. Prescott
Faculty of Science - Papers (Archive)
No abstract provided.
Synthesis Of Hyacinthacine B-3 And Purported Hyacinthacine B-7, Christopher W.G. Au, Robert J. Nash, Stephen G. Pyne
Synthesis Of Hyacinthacine B-3 And Purported Hyacinthacine B-7, Christopher W.G. Au, Robert J. Nash, Stephen G. Pyne
Faculty of Science - Papers (Archive)
The synthesis of hyacinthacines B-3 and B-7 has confirmed the structure of the former alkaloid and shown that the structure of the latter is incorrect.
Dipyridyl Beta-Diketonate Complexes: Versatile Polydentate Metalloligands For Metal-Organic Frameworks And Hydrogen-Bonded Networks, Andrew D. Burrows, Christopher G. Frost, Mary F. Mahon, Paul R. Raithby, Catherine L. Renouf, Christopher Richardson, Anna J. Stevenson
Dipyridyl Beta-Diketonate Complexes: Versatile Polydentate Metalloligands For Metal-Organic Frameworks And Hydrogen-Bonded Networks, Andrew D. Burrows, Christopher G. Frost, Mary F. Mahon, Paul R. Raithby, Catherine L. Renouf, Christopher Richardson, Anna J. Stevenson
Faculty of Science - Papers (Archive)
The Group 13 metal complexes [M(L-2)(3)], where M is Al or Ga and L-2 is 1,3-di(4-pyridyl)-1,3-propanedionato, are hexatopic metalloligands that have been used to prepare mixed-metalorganic frameworks containing interpenetrated primitive cubic networks. In contrast, the europium complex [Eu(HL2)(3)-(H2L2)]Cl-4 center dot EtOH forms a hydrogen-bonded network following partial protonation of the pyridyl groups.
Esi-Ms And Thermal Melting Studies Of Nanoscale Platinum(Ii) Metallomacrocycles With Dna, Margaret M. Harding, Louis M. Rendina, David Schilter, Thitima Urathamakul, Jennifer L. Beck
Esi-Ms And Thermal Melting Studies Of Nanoscale Platinum(Ii) Metallomacrocycles With Dna, Margaret M. Harding, Louis M. Rendina, David Schilter, Thitima Urathamakul, Jennifer L. Beck
Faculty of Science - Papers (Archive)
The hydrophilic, long-chain diamine PEGda (O,O′-bis(2-aminoethyl)octadeca(ethylene glycol)), when complexed with cis-protected Pt(II) ions afforded water-soluble complexes of the type [Pt(N,N)(PEGda)](NO3)2 (N,N = N,N,N′,N′-tetramethyl-1,2-diaminoethane (tmeda), 1,2-diaminoethane (en), and 2,2′-bipyridine (2,2′-bipy)) featuring unusual 62-membered chelate rings. Equimolar mixtures containing either the 16-mer duplex DNA D2 or the single-stranded D2a and [Pt(N,N)(PEGda)]2+ were analyzed by negative-ion ESI-MS. Analysis of D2-Pt(II) mixtures showed the formation of 1:1 adducts of [Pt(en)(PEGda)]2+, [Pt(tmeda)(PEGda)]2+ and the previously-described metallomacrocycle [Pt2(2,2′-bipy)2{4,4′-bipy(CH2)44,4′-bipy}2]8+ with D2; the dinuclear species bound to D2 most strongly, consistent with its greater charge and aromatic surface area. D2 formed 1:2 complexes with the acyclic species [Pt(2,2′-bipy)(Mebipy)2]4+ …
In Vivo Measurement Of Plant Respiration, M. Ribas-Carbo, J. Flexas, Sharon A. Robinson, G. G.B. Tcherkez
In Vivo Measurement Of Plant Respiration, M. Ribas-Carbo, J. Flexas, Sharon A. Robinson, G. G.B. Tcherkez
Faculty of Science - Papers (Archive)
Respiration is vital; it is the essence of life. Respiration is the mechanism by which energy obtained during the photosynthesis process is transformed into biochemical energy, in the form of ATP. This transformation of energy keeps all cells in all organisms alive. While energy conversion is the main function of respiration in animals, respiration has several other functions in plants. Among them, interactions with photosynthesis such as photorespiration and the production of carbon skeletons for the many compounds synthesized in plants (e.g., pigments, proteins and secondary metabolites). Therefore, it comes as no surprise that such a key role of respiration …
Flexible And Compressible Goretex-Pedot Membrane Electrodes For Solid-State Dye-Sensitized Solar Cells, Attila J. Mozer, Dillip K. Panda, Sanjeev Gambhir, Anthony C. Romeo, Bjorn Winther-Jensen, Gordon G. Wallace
Flexible And Compressible Goretex-Pedot Membrane Electrodes For Solid-State Dye-Sensitized Solar Cells, Attila J. Mozer, Dillip K. Panda, Sanjeev Gambhir, Anthony C. Romeo, Bjorn Winther-Jensen, Gordon G. Wallace
Faculty of Science - Papers (Archive)
A porous, flexible electrode based on a PTFE (Teflon) membrane (Goretex) coated with a metallic current collector and a conducting polymer (poly(3,4-ethylenedioxythiophene), PEDOT) has been developed for applications in solidstate dye-sensitized solar cells. Its low sheet resistance and compressibility make it an ideal electrode on uneven TiO2 surfaces with high efficiency and reproducibility. The porous nature of the electrode enables the feed-through of reactants and treatment agents, which opens up exciting opportunities to interface these photoelectrochemical devices with electrocatalytic, energy conversion, and storage systems. Postfabrication bonding of the photoanode and the Goretex-Au-PEDOT electrode is demonstrated.
Novel Technique Shows Different Hydrophobic Chemical Signatures Of Exotic And Indigenous Plant Soils With Similar Effects Of Extracts On Indigenous Species Seedling Growth, Emilie-Jane Ens, Kristine O. French, John B. Bremner, Jurgen Korth
Novel Technique Shows Different Hydrophobic Chemical Signatures Of Exotic And Indigenous Plant Soils With Similar Effects Of Extracts On Indigenous Species Seedling Growth, Emilie-Jane Ens, Kristine O. French, John B. Bremner, Jurgen Korth
Faculty of Science - Papers (Archive)
Changes to ecosystem abiotic parameters are regarded as possible mechanisms facilitating plant invasion and community composition shifts. This study compared the hydrophobic chemical signatures of soil from exotic bitou bush (Chrysanthemoides monilifera spp. rotundata) invaded, indigenous acacia (Acacia longifolia var. sophorae) dominated and bare sand (unvegetated) habitats using a novel, rapid, capturing technique which utilised AmberliteA (R) XAD4 resin filled bags that were placed in situ. The hydrophobic chemical signature of the bitou bush soil extract was significantly different to the acacia soil and bare sand extracts. High concentrations of 18 sesquiterpenes dominated the hydrophobic signature of the bitou bush …
Shell Artefacts And Shell-Working Within The Lapita Cultural Complex, Katherine A. Szabo
Shell Artefacts And Shell-Working Within The Lapita Cultural Complex, Katherine A. Szabo
Faculty of Science - Papers (Archive)
Despite a consistent presence in the archaeological record of the Lapita cultural complex, and their omnipresence in the associated literature, the nature and range of shell artefacts recovered from Lapita sites has only been partially summarized at best. Considering the categories of raw material choice, working techniques, formal artefact types and curation, this article summarizes our current knowledge and points to areas for further research.
Response Of Coral Reefs To Climate Change: Expansion And Demise Of The Southernmost Pacific Coral Reef, Colin D. Woodroffe, Brendan P. Brooke, Michelle Linklater, David M. Kennedy, Brian G. Jones, Cameron Buchanan, Richard Mleczko, Quan Hua, Jian-Xin Zhao
Response Of Coral Reefs To Climate Change: Expansion And Demise Of The Southernmost Pacific Coral Reef, Colin D. Woodroffe, Brendan P. Brooke, Michelle Linklater, David M. Kennedy, Brian G. Jones, Cameron Buchanan, Richard Mleczko, Quan Hua, Jian-Xin Zhao
Faculty of Science - Papers (Archive)
Coral reefs track sea level and are particularly sensitive to changes in climate. Reefs are threatened by global warming, with many experiencing increased coral bleaching. Warmer sea surface temperatures might enable reef expansion into mid latitudes. Here we report multibeam sonar and coring that reveal an extensive relict coral reef around Lord Howe Island, which is fringed by the southernmost reef in the Pacific Ocean. The relict reef, in water depths of 25-50 m, flourished in early Holocene and covered an area more than 20 times larger than the modern reef. Radiocarbon and uranium-series dating indicates that corals grew between …
Extracellular Chaperones Modulate The Effects Of Alzheimer's Patient Cerebrospinal Fluid On A Beta(1-42) Toxicity And Uptake , Justin J. Yerbury, Mark R. Wilson
Extracellular Chaperones Modulate The Effects Of Alzheimer's Patient Cerebrospinal Fluid On A Beta(1-42) Toxicity And Uptake , Justin J. Yerbury, Mark R. Wilson
Faculty of Science - Papers (Archive)
Alzheimer's disease is characterised by the inappropriate death of brain cells and accumulation of the A beta peptide in the brain. Thus, it is possible that there are fundamental differences between Alzheimer's disease patients and healthy individuals in their abilities to clear A beta from brain fluid and to protect neurons from A beta toxicity. In the present study, we examined (1) the cytotoxicity of Alzheimer's disease cerebrospinal fluid (CSF) compared to control CSF, (2) the ability of Alzheimer's disease and control CSF to protect cells from A beta toxicity and to promote cell-mediated clearance of A beta and lastly …
Population And Breeding Trends Of An Urban Coloniser: The Australian White Ibis, John Martin, Kris French, Richard Major
Population And Breeding Trends Of An Urban Coloniser: The Australian White Ibis, John Martin, Kris French, Richard Major
Faculty of Science - Papers (Archive)
Context. In the Sydney region, the population of Australian white ibis has dramatically increased from rare observations in the 1950s to a breeding season peak of 8900 in 2008, resulting with human -wildlife conflicts. Within natural habitats across the eastern states, the ibis population has declined, yet within urban environments ibis have been lethally managed for over 30 years. However, limited ecological and no regional population data are available for the Sydney region. Aims. The present study of ibis in the Sydney region aims to (1) establish the abundance of the population during the breeding and non-breeding seasons, (2) determine …
Ionic Liquid Electrolyte Porphyrin Dye Sensitised Solar Cells, Vanessa Armel, Jennifer Pringle, Maria Forsyth, Douglas Macfarlane, David L. Officer, Pawel W. Wagner
Ionic Liquid Electrolyte Porphyrin Dye Sensitised Solar Cells, Vanessa Armel, Jennifer Pringle, Maria Forsyth, Douglas Macfarlane, David L. Officer, Pawel W. Wagner
Faculty of Science - Papers (Archive)
Ionic liquid electrolytes based on a number of imidazolium, quaternary ammonium and phosphonium cations have been developed for porphyrin dye sensitised solar cells yielding efficiencies of up to 5.2% at 0.68 Sun.
Evidence For Specific Subunit Distribution And Interactions In The Quaternary Structure Of Α-Crystallin, Amie M. Morris, J Andrew Aquilina
Evidence For Specific Subunit Distribution And Interactions In The Quaternary Structure Of Α-Crystallin, Amie M. Morris, J Andrew Aquilina
Faculty of Science - Papers (Archive)
The quaternary structure of alpha-crystallin is dynamic, a property which has thwarted crystallographic efforts towards structural characterization. In this study, we have used collision-induced dissociation mass spectrometry to examine the architecture of the polydisperse assemblies of alpha-crystallin. For total alpha-crystallin isolated directly from fetal calf lens using size-based chromatography, the alpha B-crystallin subunit was found to be preferentially dissociated from the oligomers, despite being significantly less abundant overall than the alpha A-crystallin subunits. Furthermore, upon mixing molar equivalents of purified alpha A- and alpha B-crystallin, the levels of their dissociation were found to decrease and increase, respectively, with time. Interestingly …
Microsecond Dye Regeneration Kinetics In Efficient Solid State Dye-Sensitized Solar Cells Using A Photoelectrochemically Deposited Pedot Hole Conductor, Attila J. Mozer, Dillip K. Panda, Sanjeev Gambhir, B. Winther-Jensen, Gordon G. Wallace
Microsecond Dye Regeneration Kinetics In Efficient Solid State Dye-Sensitized Solar Cells Using A Photoelectrochemically Deposited Pedot Hole Conductor, Attila J. Mozer, Dillip K. Panda, Sanjeev Gambhir, B. Winther-Jensen, Gordon G. Wallace
Faculty of Science - Papers (Archive)
Microsecond dye-regeneration kinetics was observed in efficient solid state dye-sensitized solar cells using photoelectrochemically deposited poly(3,4-ethylenedioxythiophene (PEDOT) hole conductors using transient absorption spectroscopy. The dye-regeneration rate is orders of magnitude slower than the case using the I-/I3- redox couple or commonly used small molecule hole conductor and is attributed to the low dye to PEDOT ratio within the films.
Effects Of Soil Temperature Regimes After Fire On Seed Dormancy And Germination In Six Australian Fabaceae Species, Victor Santana, Ross A. Bradstock, Mark Ooi, Andrew J. Denham, Tony D. Auld, M Baeza
Effects Of Soil Temperature Regimes After Fire On Seed Dormancy And Germination In Six Australian Fabaceae Species, Victor Santana, Ross A. Bradstock, Mark Ooi, Andrew J. Denham, Tony D. Auld, M Baeza
Faculty of Science - Papers (Archive)
In addition to direct fire cues such as heat, smoke and charred wood, the passage of fire leads indirectly to changes in environmental conditions which may be able to break physical dormancy in hard-coated seeds. After a fire, the open canopy and the burnt material lying on the surface alter the thermal properties of the soil, resulting in elevated soil temperatures for long periods of time. We simulated daily temperature regimes experienced at different depths of soil profile after a summer fire. Our aim was to determine whether these temperature regimes and the duration of exposure (5, 15 and 30 …
Sex Ratio Of Breeding Common Toads (Bufo Bufo) - Influence Of Survival And Skipped Breeding, Jon Loman, Thomas R. Madsen
Sex Ratio Of Breeding Common Toads (Bufo Bufo) - Influence Of Survival And Skipped Breeding, Jon Loman, Thomas R. Madsen
Faculty of Science - Papers (Archive)
Anuran sex ratio at breeding sites is typically male biased. Such sex ratios may be due to poor female survival, to females not breeding as frequently as males and/or to males becoming sexually mature earlier than females. In the present study, the first two factors are analyzed in a common toad (Bufo bufo) population in southern Sweden. Toads were captured, marked and recaptured at the breeding site during 5 years. Within season capture patterns were analyzed using the Jolly-Seber model and among-year captures using the Closed robust design model. Population estimates of males and females yielded an among year variation …
Differential Endocytosis Of Tissue Plasminogen Activator By Serpins Pai-1 And Pai-2 On Human Peripheral Blood Monocytes, Jodi A. Lee, David Croucher, Marie Ranson
Differential Endocytosis Of Tissue Plasminogen Activator By Serpins Pai-1 And Pai-2 On Human Peripheral Blood Monocytes, Jodi A. Lee, David Croucher, Marie Ranson
Faculty of Science - Papers (Archive)
Generation of the broad spectrum protease plasmin is facilitated by the tissue (t-PA) and urokinase (u-PA) plasminogen activators, within multiple physiological and disease states. Finely tuned control of this proteolytic cascade is exerted by the plasminogen activator inhibitors type-1 (PAI-1/SERPINE1) and 2 (PAI-2/SERPINB2). Expression of this network of activators and inhibitors by cells of myeloid lineage appears to be highly interchangeable between physiological environments, and whilst the role of PAI-1 and PAI-2 in regulating u-PA-dependent functions is well established, the interaction between t-PA and PAI-2 on these cell types is poorly characterised. To this end, we used freshly isolated peripheral …
New Data On Occurrences Of The Devonian Rugose Coral Calceola In Belgium, Anthony J. Wright, M Coen-Aubert, P Bultynck, A P. Van Viersen
New Data On Occurrences Of The Devonian Rugose Coral Calceola In Belgium, Anthony J. Wright, M Coen-Aubert, P Bultynck, A P. Van Viersen
Faculty of Science - Papers (Archive)
Opercula and corallites of Calceola sandalina from the late Eifelian and early Givetian (Middle Devonian) Hanonet Formation of Belgium are illustrated. The few previous illustrations of calceoloid corals from the Devonian of Belgium did not include opercula showing the generically diagnostic morphological features, so for the first time the presence of the genus and species in Belgium is confirmed. One important corallite shows the alar septum and insertion of septa on the external surface of the counter face adjacent to the alar septum.
What Did Grinding Stones Grind? New Light On Early Neolithic Subsistence Economy In The Middle Yellow River Valley, China, Li Liu, Judith Field, Richard Fullagar, Sheahan Bestel, Xingcan Chen, Xiaolin Ma
What Did Grinding Stones Grind? New Light On Early Neolithic Subsistence Economy In The Middle Yellow River Valley, China, Li Liu, Judith Field, Richard Fullagar, Sheahan Bestel, Xingcan Chen, Xiaolin Ma
Faculty of Science - Papers (Archive)
Grinding stones have provided a convenient proxy for the arrival of agriculture in Neolithic China. Not any more. Thanks to high-precision analyses of use-wear and starch residue, the authors show that early Neolithic people were mainly using these stones to process acorns. This defines a new stage in the long transition of food production from hunter-gatherer to farmer.
Sustainability Potential Of Suburban Gardens: Review And New Directions, Sumita Ghosh
Sustainability Potential Of Suburban Gardens: Review And New Directions, Sumita Ghosh
Faculty of Science - Papers (Archive)
Gardens, as important elements of Australian suburban residential environments, could have significant sustainability potential similar to that of dwellings. Research to identify the cumulative (social, cultural, environmental and ecological) sustainability values of suburban domestic gardens has been very limited. Australian suburbs are likely to retain their typical characteristics for a considerable period of time as their rapid intensification is not likely. Therefore, it is immensely important to understand the role and performance of the suburban garden in this discourse. This article reviews the sustainability potential of domestic gardens and their links to suburban forms, sustainable design, social processes, and environmental …
Catchments And Waterways, Bob Bourman, Nick Harvey, Simon Bryars
Catchments And Waterways, Bob Bourman, Nick Harvey, Simon Bryars
Faculty of Science - Papers (Archive)
No abstract provided.
A Petrological, Mineralogical And Geochemical Analysis Of Listwaenite Alteration At Spring Creek Bingara In The Great Serpentinite Belt, New England, Nsw, E Holcroft, Solomon Buckman, I Neuss
A Petrological, Mineralogical And Geochemical Analysis Of Listwaenite Alteration At Spring Creek Bingara In The Great Serpentinite Belt, New England, Nsw, E Holcroft, Solomon Buckman, I Neuss
Faculty of Science - Papers (Archive)
No abstract provided.
Silica-Carbonate (Listwanites) Related Gold Mineralisation Associated With Epithermal Alteration Of Serpentinite Bodies, Solomon Buckman, P Ashley
Silica-Carbonate (Listwanites) Related Gold Mineralisation Associated With Epithermal Alteration Of Serpentinite Bodies, Solomon Buckman, P Ashley
Faculty of Science - Papers (Archive)
No abstract provided.
Co-Located Column And In Situ Measurements Of Co2 In The Tropics Compared With Model Simulations, T Warneke, A K. Petersen, C Gerbig, A Jordan, C Rodenbeck, M Rothe, Ronald Macatangay, J Norholt, O Schrems
Co-Located Column And In Situ Measurements Of Co2 In The Tropics Compared With Model Simulations, T Warneke, A K. Petersen, C Gerbig, A Jordan, C Rodenbeck, M Rothe, Ronald Macatangay, J Norholt, O Schrems
Faculty of Science - Papers (Archive)
The first ground-based remote sensing measurements of the column averaged volume mixing ratio of CO2 (XCO2) in tropical South America have been obtained at Paramaribo, Suriname (5.8 N, 55.2 W). The remote sensing observations are complemented by surface air-samples collected at the site, analyzed for CO2 and 13CO2. The surface in-situ measurements are strongly influenced by local sources. From the isotopic composition of the air samples the local source component is suggested to be dominated by the terrestrial biosphere. Using 13C from the NOAA/ESRL stations Ascension Is. (ASC), 7.9 S, 14.4W, and Ragged Point (RPB), 13.2 N, 59.4W, the data …
In Vivo Measurement Of Plant Respiration, Miquel Ribas-Carbo, Jaume Flexas, Sharon A. Robinson, Guillaume G. B Tcherkez
In Vivo Measurement Of Plant Respiration, Miquel Ribas-Carbo, Jaume Flexas, Sharon A. Robinson, Guillaume G. B Tcherkez
Faculty of Science - Papers (Archive)
Respiration is vital; it is the essence of life. Respiration is the mechanism by which energy obtained during the photosynthesis process is transformed into biochemical energy, in the form of ATP. This transformation of energy keeps all cells in all organisms alive. While energy conversion is the main function of respiration in animals, respiration has several other functions in plants. Among them, interactions with photosynthesis such as photorespiration and the production of carbon skeletons for the many compounds synthesized in plants (e.g., pigments, proteins and secondary metabolites). Therefore, it comes as no surprise that such a key role of respiration …
Influence Of Polyunsaturated Fatty Acids On Intestinal Barrier Function During Colitis, Bianca Knoch, Warren C. Mcnabb, Nicole Roy
Influence Of Polyunsaturated Fatty Acids On Intestinal Barrier Function During Colitis, Bianca Knoch, Warren C. Mcnabb, Nicole Roy
Faculty of Science - Papers (Archive)
Tight junction proteins are important for intestinal homeostasis. They prevent paracellular transport of large molecules and maintain cell polarity. Impaired tight junction function leads to a more permeable intestinal epithelial barrier and therefore potentially increases disease risk. Limited information is available concerning the effects of food components on the intestinal barrier, particularly paracellular permeability and tight junction proteins. In vitro studies with intestinal epithelial cells and in vivo studies using animal models have demonstrated that dietary n-3 and n-6 polyunsaturated fatty acids (PUFAs), particularly n-3, can reduce intestinal inflammation and permeability. PUFAs can induce transcriptional regulators which may act in …
The Interaction Of Alphab-Crystallin With Mature Alpha-Synuclein Amyloid Fibrils Inhibits Their Elongation, Christopher A. Waudby, Tuomas P. J Knowles, Glyn L. Devlin, Jeremy N. Skepper, Heath Ecroyd, John A. Carver, Mark E. Welland, John Christodoulou, Christopher M. Dobson, Sarah Meehan
The Interaction Of Alphab-Crystallin With Mature Alpha-Synuclein Amyloid Fibrils Inhibits Their Elongation, Christopher A. Waudby, Tuomas P. J Knowles, Glyn L. Devlin, Jeremy N. Skepper, Heath Ecroyd, John A. Carver, Mark E. Welland, John Christodoulou, Christopher M. Dobson, Sarah Meehan
Faculty of Science - Papers (Archive)
alphaB-Crystallin is a small heat-shock protein (sHsp) that is colocalized with alpha-synuclein (alphaSyn) in Lewy bodies—the pathological hallmarks of Parkinson's disease—and is an inhibitor of alphaSyn amyloid fibril formation in an ATP-independent manner in vitro. We have investigated the mechanism underlying the inhibitory action of sHsps, and here we establish, by means of a variety of biophysical techniques including immunogold labeling and nuclear magnetic resonance spectroscopy, that alphaB-crystallin interacts with alphaSyn, binding along the length of mature amyloid fibrils. By measurement of seeded fibril elongation kinetics, both in solution and on a surface using a quartz crystal microbalance, this binding …
Alphab-Crystallin Inhibits The Cell Toxicity Associated With Amyloid Fibril Formation By Kappa-Casein And The Amyloid-Beta Peptide, Francis C. Dehle, Heath Ecroyd, Ian F. Musgrave, John A. Carver
Alphab-Crystallin Inhibits The Cell Toxicity Associated With Amyloid Fibril Formation By Kappa-Casein And The Amyloid-Beta Peptide, Francis C. Dehle, Heath Ecroyd, Ian F. Musgrave, John A. Carver
Faculty of Science - Papers (Archive)
Amyloid fibril formation is associated with diseases such as Alzheimer’s, Parkinson’s, and prion diseases. Inhibition of amyloid fibril formation by molecular chaperone proteins, such as the small heat-shock protein αB-crystallin, may play a protective role in preventing the toxicity associated with this form of protein misfolding. Reduced and carboxymethylated κ-casein (RCMκ-CN), a protein derived from milk, readily and reproducibly forms fibrils at physiological temperature and pH. We investigated the toxicity of fibril formation by RCMκ-CN using neuronal model PC12 cells and determined whether the inhibition of fibril formation altered its cell toxicity. To resolve ambiguities in the literature, we also …
Plate Driven Extension And Convergence Along The East Gondwana Active Margin: Late Silurian–Middle Devonian Tectonics Of The Lachlan Fold Belt, Southeastern Australia, Christopher L. Fergusson
Plate Driven Extension And Convergence Along The East Gondwana Active Margin: Late Silurian–Middle Devonian Tectonics Of The Lachlan Fold Belt, Southeastern Australia, Christopher L. Fergusson
Faculty of Science - Papers (Archive)
The Lachlan Fold Belt of southeastern Australia developed along the Panthalassan margin of East Gondwana. Major silicic igneous activity and active tectonics with extensional, strike-slip and contractional deformation have been related to a continental backarc setting with a convergent margin to the east. In the Early Silurian (Benambran Orogeny), tectonic development was controlled by one or more subduction zones involved in collision and accretion of the Ordovician Macquarie Arc. Thermal instability in the Late Silurian to Middle Devonian interval was promoted by the presence of one or more shallow subducted slabs in the upper mantle and resulted in widespread silicic …