Physical Sciences and Mathematics Commons^™

Wordless Intervention For Epilepsy In Learning Disabilities (Wield): Study Protocol For A Randomized Controlled Feasibility Trial, Marie-Anne Durand, Bob Gates, Georgina Parkes, Asif Zia

Dartmouth Scholarship

Epilepsy is the most common neurological problem that affects people with learning disabilities. The high seizure frequency, resistance to treatments, associated skills deficit and co-morbidities make the management of epilepsy particularly challenging for people with learning disabilities. The Books Beyond Words booklet for epilepsy uses images to help people with learning disabilities manage their condition and improve quality of life. Our aim is to conduct a randomized controlled feasibility trial exploring key methodological, design and acceptability issues, in order to subsequently undertake a large-scale randomized controlled trial of the Books Beyond Words booklet for epilepsy.

Constrained Bayesian Estimation Of Inverse Probability Weights For Nonmonotone Missing Data, Baoluo Sun, Eric J. Tchetgen Tchetgen

Harvard University Biostatistics Working Paper Series

No abstract provided.

Should We Love Or Hate Big Data? The Good, The Bad, And The Ugly, Dennis Crossen M.Sc., Mba, Karti Puranam Phd, Madjid Tavana Phd

Explorer Café

No abstract provided.

Mantle-Crust Interaction In Granite Petrogenesis In Post-Collisional Settings: Insights From The Danubian Variscan Plutons Of The Romanian Southern Carpathians, Ciprian Cosmin Stremtan

USF Tampa Graduate Theses and Dissertations

The issue of granite petrogenesis plays a key role in our overall understanding of the growth and differentiation of continents, as well as in our ability to unravel the tectonic histories of orogenic belts. Granites are ubiquitous magmatic products found in almost all tectonic settings: oceanic and continental rifts (i.e., plagiogranites - extreme basalt differentiates), active continental margins (e.g,. the granitic batholiths of central and southern Andes), continent-continent collision zones (e.g., the orogenic batholiths of the Himalayas, Western Anatolia), post-collisional settings (e.g., the Variscan provinces of Europe), complex within-plates settings (e.g., Limmo massif, Afar, Ethiopia). Furthermore, granitoids are characterized by …

Cosm News, Georgia Southern University

College of Science and Mathematics News (2012-2019)

• Grad Student & Professor featured in GS Foundation Annual Report

It's A Small World After All – And We're All Connected, Alaina Bernard

UCF Forum

We’ve probably all had the song “it’s a small world” stuck in our heads after visiting Fantasyland at Walt Disney World. This simple song highlights how we all are connected, and was created to promote the message of international peace and inclusion of diversity. Walt Disney sped up the tempo from the original version and made it more cheery, but it is arguably a simple message that we continue to strive for decades later.

Co(Ii) Based Metalloradical Catalysis: Carbene And Nitrene Transfer Reactions, Joseph B. Gill

USF Tampa Graduate Theses and Dissertations

Radical chemistry has attracted a large amount of research interest over the last few decades and radical reactions have recently been recognized as powerful tools for organic synthesis. The synthetic applications of radicals have been demonstrated in many fields, including in the synthesis of complex natural products. Radical reactions have a number of inherent synthetic advantages over their ionic counterparts. For example, they typically proceed at fast reaction rates under mild and neutral conditions in a broad spectrum of solvents and show significantly greater functional group tolerance. Furthermore, radical processes have the capability of performing in a cascade fashion, allowing …

Metallopeptides From Design To Catalysis: Structure, Oxidative Activities, And Inhibition Studies Of Designed And Naturally Occurring Metallopeptides, Alaa Hassan Hashim

USF Tampa Graduate Theses and Dissertations

Structural and mechanistic complexities of copper-dioxygen systems have attracted much attention in the field of bioinorganic chemistry, both in model systems and trapped protein intermediates. The research presented herein is focused on model and naturally occurring metallopeptide systems, from its design to catalysis. Copper is used as the coordinating metal ion, with cobalt and zinc as probes for metal binding. The bioinorganic chemistry of copper proteins and its coordination and spectroscopic properties are briefly discussed in chapter 1. The next two chapters are centered on the de novo design of a minimalistic metallopeptide system with an amino acid sequence of …

Volunteer Studies In Pain Research — Opportunities And Challenges To Replace Animal Experiments: The Report And Recommendations Of A Focus On Alternatives Workshop, C. K. Langley, Q. Aziz, C. Bountra, N. Gordon, P. Hawkins, A. Jones, G. Langley, T. Nurmikko, I. Tracey

Gill Langley, PhD

Despite considerable research, effective and safe treatments for human pain disorders remain elusive. Understanding the biology of different human pain conditions and researching effective treatments continue to be dominated by animal models, some of which are of limited value. British and European legislation demands that non-animal approaches should be considered before embarking on research using experimental animals. Recent scientific and technical developments, particularly in human neuroimaging, offer the potential to replace some animal procedures in the study of human pain. A group of pain research experts from academia and industry met with the aim of exploring creatively the tools, strategies …

The Validity Of Animal Experiments In Medical Research, Gill Langley

Gill Langley, PhD

Other animals, such as mice, rats, rabbits, dogs and monkeys, are widely used as surrogates for humans in fundamental medical research. This involves creating disorders in animals by chemical, surgical or genetic means, with the aim of mimicking selected aspects of human illnesses. It is a truism that any model or surrogate is not identical to the target being modelled. So, in medical research, experiments using animals or cell cultures or even healthy volunteers instead of patients (being the target population with the target illness) will inevitably have limitations, although these will be greater or lesser depending on the model.

U.S. Drought Monitor, November 18, 2014, Eric Luebehusen

United States Agricultural Commodities in Drought Archive

Drought map of U.S. for November 18, 2014 (11/18/14) plus: U.S. crop areas experiencing drought (map), Approximate percentage of crop located in drought, by state (bar graph), Percent of crop area located in drought, past 52 weeks (line graph) for: Corn, Soybeans, Hay, Cattle, Winter wheat.

Vegetation Controls On Weathering Intensity During The Last Deglacial Transition In Southeast Africa, Sarah J. Ivory, Michael M. Mcglue, Geoffrey S. Ellis, Anne-Marie Lézine, Andrew S. Cohen, Annie Vincens

Earth and Environmental Sciences Faculty Publications

Tropical climate is rapidly changing, but the effects of these changes on the geosphere are unknown, despite a likelihood of climatically-induced changes on weathering and erosion. The lack of long, continuous paleo-records prevents an examination of terrestrial responses to climate change with sufficient detail to answer questions about how systems behaved in the past and may alter in the future. We use high-resolution records of pollen, clay mineralogy, and particle size from a drill core from Lake Malawi, southeast Africa, to examine atmosphere-biosphere-geosphere interactions during the last deglaciation (~ 18-9 ka), a period of dramatic temperature and hydrologic changes. The …

Testing Gene-Environment Interactions In The Presence Of Measurement Error, Chongzhi Di, Li Hsu, Charles Kooperberg, Alex Reiner, Ross Prentice

UW Biostatistics Working Paper Series

Complex diseases result from an interplay between genetic and environmental risk factors, and it is of great interest to study the gene-environment interaction (GxE) to understand the etiology of complex diseases. Recent developments in genetics field allows one to study GxE systematically. However, one difficulty with GxE arises from the fact that environmental exposures are often measured with error. In this paper, we focus on testing GxE when the environmental exposure E is subject to measurement error. Surprisingly, contrast to the well-established results that the naive test ignoring measurement error is valid in testing the main effects, we find that …

Temperature-Induced Viral Resistance In Emiliania Huxleyi (Prymnesiophyceae), B. Jacob Kendrick, Giacomo R. Ditullio, Tyler Cyronak, James M. Fulton, Benjamin A. S. Van Mooy, Kay D. Bidle

Marine & Environmental Sciences Faculty Articles

Annual Emiliania huxleyi blooms (along with other coccolithophorid species) play important roles in the global carbon and sulfur cycles. E. huxleyi blooms are routinely terminated by large, host-specific dsDNA viruses, (Emiliania huxleyi Viruses; EhVs), making these host-virus interactions a driving force behind their potential impact on global biogeochemical cycles. Given projected increases in sea surface temperature due to climate change, it is imperative to understand the effects of temperature on E. huxleyi’s susceptibility to viral infection and its production of climatically active dimethylated sulfur species (DSS). Here we demonstrate that a 3°C increase in temperature induces EhV-resistant phenotypes …

Anonymized Video Analysis Methods And Systems, Marjorie Skubic, James M. Keller, Fang Wang, Derek T. Anderson, Erik Stone, Robert H. Luke Iii, Tanvi Banerjee, Marilyn J. Rantz

Kno.e.sis Publications

Methods and systems for anonymized video analysis are described. In one embodiment, a first silhouette image of a person in a living unit may be accessed. The first silhouette image may be based on a first video signal recorded by a first video camera. A second silhouette image of the person in the living unit may be accessed. The second silhouette image may be of a different view of the person than the first silhouette image. The second silhouette image may be based on a second video signal recorded by a second video camera. A three-dimensional model of the person …

Paraxial Ray Optics Cloaking, Joseph S. Choi, John C. Howell

Mathematics, Physics, and Computer Science Faculty Articles and Research

Despite much interest and progress in optical spatial cloaking, a three-dimensional (3D), transmitting, continuously multidirectional cloak in the visible regime has not yet been demonstrated. Here we experimentally demonstrate such a cloak using ray optics, albeit with some edge effects. Our device requires no new materials, uses isotropic off-the-shelf optics, scales easily to cloak arbitrarily large objects, and is as broadband as the choice of optical material, all of which have been challenges for current cloaking schemes. In addition, we provide a concise formalism that quantifies and produces perfect optical cloaks in the small-angle (‘paraxial’) limit.

Electrostatic Breakdown Analysis, Sam Hansen, Jr Dennison, Allen Andersen

Senior Theses and Projects

Materials potentially suitable for spacecraft construction were exposed to electrostatic discharge in the USU Materials Physics Group lab, with hopes of identifying samples that possess greater resistance to breakdown. Breakdown shape and size may be important to determining material suitability for spacecraft construction [1]. The discharge damage sites of tested samples were examined, measured and logged into a matrix file for data analysis. Once logged, data was sorted within the matrix and compared graphically to identify trends.

Electrostatic Breakdown Analysis, Sam Hansen

Senior Theses and Projects

Materials potentially suitable for spacecraft construction were exposed to electrostatic discharge in the USU Materials Physics Group lab, with hopes of identifying samples that possess greater resistance to breakdown. Breakdown shape and size may be important to determining material suitability for spacecraft construction [1]. The discharge damage sites of tested samples were examined, measured and logged into a matrix file for data analysis. Once logged, data was sorted within the matrix and compared graphically to identify trends.

Magneto-Optical Kerr Eect Study Of Magnetic Anisotropy In Soft Ferromagnets, Tatiana Marie Eggers

USF Tampa Graduate Theses and Dissertations

The continued progress of modern information technology relies on understanding the influence of magnetic anisotropy on magnetic thin films. In this work, two sources of magnetic anisotropy are examined in two different soft ferromagnets: a uniaxial anisotropy induced during the fabrication of Ni₈₀Fe₂₀ and exchange anisotropy, or exchange bias, which occurs at the interface of Ni₇₇Fe₁₄Cu₅Mo₄/Fe₅₀Mn₅₀ bilayer. A home-built Magneto-optical Kerr effect magnetometer is used to measure the magnetic response of the soft ferromagnetic films and details of its construction are also discussed. A simple model …

Cosm News, Georgia Southern University

College of Science and Mathematics News (2012-2019)

• Biology Student & Faculty featured in GS Foundation Annual Report

Tools For Managing The Past Web, Michele C. Weigle, Michael L. Nelson, Yasmin Alnoamany, Ahmed Alsum, Justin Brunelle, Mat Kelly, Hany Salaheldeen

Computer Science Presentations

PDF of a powerpoint presentation from the Archive-It Partners Meeting in Montgomery, Alabama, November 18, 2014. Also available on Slideshare.

Search For New Resonances Decaying Via Wz To Leptons In Proton–Proton Collisions At √S=8 Tev, Cms Collaboration, Cern, Switzerland, Samantha Hewamanage, Stephan Linn, Pete E. Markowitz, German Martinez, Jorge Luis Rodriguez

Department of Physics

A search is performed in proton–proton collisions at √s=8TeVfor exotic particles decaying via WZ to fully leptonic final states with electrons, muons, and neutrinos. The data set corresponds to an integrated luminosity of 19.5fb−1. No significant excess is observed above the expected standard model background. Upper bounds at 95% confidence level are set on the production cross section of a Wboson as predicted by an extended gauge model, and on the WW Zcoupling. The expected and observed mass limits for a Wboson, as predicted by this model, are 1.55 and 1.47TeV, respectively. Stringent limits are also set in the context …

Water Scarcity In The Jordan River Basin, Matthew Cook

Scholarly Horizons: University of Minnesota, Morris Undergraduate Journal

The watershed of the Jordan River stretches over four countries – Jordan, Syria, Israel, and Lebanon – and includes the region of Palestine. With the land and its resources hotly contested by all parties involved, the dwindling supply of drinking and irrigation water from viable sources has led to scrambling exploitation, leaving the river and its connected lakes in an ever-worsening state of deterioration. Increased suspended solids, presence of toxin-producing cyanobacteria, and accelerated evapotranspiration have led to a slower, shallower, murkier, and lower health quality trickle taking the place of the once-revered River Jordan (Comair et al., “Watershed Delineation” …

Conversion Of Red Fluorescent Protein Into A Bright Blue Probe, Oksana M. Subach, Illia S. Gundorov, Masami Yoshimura, Fedor V. Subach, Jinghang Zhang, David Grunwald, Ekaterina A. Souslova, Dmitriy M. Chudakov, Vladislav V. Verkhusha

David Grünwald

We used a red chromophore formation pathway, in which the anionic red chromophore is formed from the neutral blue intermediate, to suggest a rational design strategy to develop blue fluorescent proteins with a tyrosine-based chromophore. The strategy was applied to red fluorescent proteins of the different genetic backgrounds, such as TagRFP, mCherry, HcRed1, M355NA, and mKeima, which all were converted into blue probes. Further improvement of the blue variant of TagRFP by random mutagenesis resulted in an enhanced monomeric protein, mTagBFP, characterized by the substantially higher brightness, the faster chromophore maturation, and the higher pH stability than blue fluorescent proteins …

Multi-Messenger Search For Sources Of Gravitational Waves And High-Energy Neutrinos: Initial Results For Ligo-Virgo And Icecube, M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, D. Altmann, Marc Favata, Shaon Ghosh, Rodica Martin

Department of Physics and Astronomy Faculty Scholarship and Creative Works

We report the results of a multimessenger search for coincident signals from the LIGO and Virgo gravitational-wave observatories and the partially completed IceCube high-energy neutrino detector, including periods of joint operation between 2007-2010. These include parts of the 2005-2007 run and the 2009-2010 run for LIGO-Virgo, and IceCube's observation periods with 22, 59 and 79 strings. We find no significant coincident events, and use the search results to derive upper limits on the rate of joint sources for a range of source emission parameters. For the optimistic assumption of gravitational-wave emission energy of 10-2M c2 at ∼150Hz with ∼60ms duration, …

Hacking Back: Not The Right Solution, Emilio Iasiello

Emilio Iasiello

In cyberspace attackers enjoy an advantage over defenders, which has popularized the concept of “active cyber defense”— offensive actions intended to punish or deter the adversary. This article argues active cyber defense is not a practical course of action to obtain tactical and strategic objectives. Instead, “aggressive cyber defense,” a proactive security solution, is a more appropriate option.

Cosm News, Georgia Southern University

College of Science and Mathematics News (2012-2019)

• U.S. National Tick Collection Temporarily Closed

Evolution Of Acyl-Substrate Recognition By A Family Of Acyl-Homoserine Lactone Synthases, Quin H. Christensen, Ryan M. Brecht, Dastagiri Dudekula, E. Peter Greenberg, Rajesh Nagarajan

Chemistry and Biochemistry Faculty Publications and Presentations

Members of the LuxI protein family catalyze synthesis of acyl-homoserine lactone (acyl-HSL) quorum sensing signals from S-adenosyl-L-methionine and an acyl thioester. Some LuxI family members prefer acyl-CoA, and others prefer acyl-acyl carrier protein (ACP) as the acyl-thioester substrate. We sought to understand the evolutionary history and mechanisms mediating this substrate preference. Our phylogenetic and motif analysis of the LuxI acyl-HSL synthase family indicates that the acyl-CoA-utilizing enzymes evolved from an acyl-ACP-utilizing ancestor. To further understand how acyl-ACPs and acyl-CoAs are recognized by acyl-HSL synthases we studied BmaI1, an octanoyl-ACP-dependent LuxI family member from Burkholderia mallei, and BjaI, an …

University Professors’ Perceptions About The Impact Of Integrating Google Applications On Students’ Communication And Collaboration Skills, Jacqueline L. Cahill

Journal of Research Initiatives

A qualitative research study was conducted and data were collected by interviewing university professors on their perceptions about the impact of integrating Google Apps, as a means of classroom instructional delivery, on students’ communication and collaboration skills. The participants consisted of eight university professors from a major university, who integrate, or had previously integrated at least two Google Apps Education Edition collaborative tools into their instructional strategies. The result of this study has the potential to benefit universities that are debating on whether utilizing teaching collaborative technology skills, as an instruction tool, would engage students and enhance their communication skills. …

Multimessenger Search For Sources Of Gravitational Waves And High-Energy Neutrinos: Initial Results For Ligo-Virgo And Icecube, M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, D. Altmann, T. Anderson, C. Arguelles, T. C. Arlen, J. Auffenberg, X. Bai, S. W. Barwick, V. Baum, J. J. Beatty, J. Becker Tjus, K. H. Becker, S. Benzvi, P. Berghaus, D. Berley, E. Bernardini, A. Bernhard, D. Z. Besson, G. Binder, D. Bindig, M. Bissok, E. Blaufuss, J. Blumenthal, D. J. Boersma, C. Bohm

Physics and Astronomy Faculty Publications and Presentations

We report the results of a multimessenger search for coincident signals from the LIGO and Virgo gravitational-wave observatories and the partially completed IceCube high-energy neutrino detector, including periods of joint operation between 2007-2010. These include parts of the 2005-2007 run and the 2009-2010 run for LIGO-Virgo, and IceCube's observation periods with 22, 59 and 79 strings. We find no significant coincident events, and use the search results to derive upper limits on the rate of joint sources for a range of source emission parameters. For the optimistic assumption of gravitational-wave emission energy of 10-2M c2 at ∼150Hz with ∼60ms duration, …