Physical Sciences and Mathematics Commons^™

Anthropogenic Controls On Overwash Deposition: Evidence And Consequences, Laura Rogers, Laura Moore, Evan Goldstein, Christopher Hein, Jorge Lorenzo Trueba, Andrew Ashton

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Accelerated sea level rise and the potential for an increase in frequency of the most intense hurricanes due to climate change threaten the vitality and habitability of barrier islands by lowering their relative elevation and altering frequency of overwash. High-density development may further increase island vulnerability by restricting delivery of overwash to the subaerial island. We analyzed pre-Hurricane Sandy and post-Hurricane Sandy (2012) lidar surveys of the New Jersey coast to assess human influence on barrier overwash, comparing natural environments to two developed environments (commercial and residential) using shore-perpendicular topographic profiles. The volumes of overwash delivered to residential and commercial …

Geology In Environmental Management, Michael A. Kruge

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

From the geological perspective, the two overriding environmental management concerns are the destructive impact of hazardous natural events on human health and property and the deleterious impact of human activity on the natural environment. The knowledge derived from the geological sciences serves as the basis for a more enlightened approach to the reduction of unnecessary risk involved in the siting and construction of buildings and transportation networks, as well as the extraction of natural resources and waste management. Armed with such knowledge along with political sensitivity, environmental managers will have opportunities for positive social impact in negotiating the challenges as …

Taming The Hurricane Of Acquisition Cost Growth – Or At Least Predicting It, Allen J. Deneve, Erin T. Ryan, Jonathan D. Ritschel, Christine M. Schubert Kabban

Faculty Publications

Cost growth is a persistent adversary to efficient budgeting in the Department of Defense. Despite myriad studies to uncover causes of this cost growth, few of the proposed remedies have made a meaningful impact. A key reason may be that DoD cost estimates are formulated using the highly unrealistic assumption that a program’s current baseline characteristics will not change in the future. Using a weather forecasting analogy, the authors demonstrate how a statistical approach may be used to account for these inevitable baseline changes and identify related cost growth trends. These trends are then used to reduce the error in …

The Finite Embeddability Property For Some Noncommutative Knotted Varieties Of Rl And Drl, Riquelmi Salvador Cardona Fuentes

Electronic Theses and Dissertations

Residuated lattices, although originally considered in the realm of algebra providing a general setting for studying ideals in ring theory, were later shown to form algebraic models for substructural logics. The latter are non-classical logics that include intuitionistic, relevance, many-valued, and linear logic, among others. Most of the important examples of substructural logics are obtained by adding structural rules to the basic logical calculus FL. We denote by 𝖱𝖫𝑛 � the varieties of knotted residuated lattices. Examples of these knotted rules include integrality and contraction. The extension of �� by the rules corresponding to these two equations is …

New Methods For Measuring Transient Interactions Between Proteins And Curved Membranes, Philip P. Cheney

Electronic Theses and Dissertations

Variations in the physical deformation of the plasma membrane play a significant role in the sorting and behavior of the proteins that occupy it. Determining the interplay between membrane curvature and protein behavior required the development and thorough characterization of a model plasma membrane with well defined and localized regions of curvature. This model system consists of a fluid lipid bilayer that is supported by a dye-loaded polystyrene nanoparticle patterned glass substrate. As the physical deformation of the supported lipid bilayer is essential to our understanding of the behavior of the protein occupying the bilayer, extensive characterization of the structure …

When Wells Run Dry: Water And Tourism Along The Western Coast Of Nicaragua, Gary Thomas Lavanchy

Electronic Theses and Dissertations

This dissertation uses a political ecology approach to examine the relationship between tourism development and groundwater in southwest Nicaragua. Tourism in Nicaragua is a booming industry bolstered by ‘unspoiled’ natural beauty, low crime rates, and government incentives. This growth has led to increased infrastructure, revenue, and employment opportunities for many local communities along the Pacific coast. Not surprisingly, it has also brought concomitant issues of deeper poverty, widening gaps between rich and poor, and competition over natural resources. Adequate provisions of freshwater are necessary to sustain the production and reproduction of tourism; however, it remains uncertain if groundwater supplies can …

Rapid Scan Electron Paramagnetic Resonance (Epr) And Digital Epr Development, Zhelin Yu

Electronic Theses and Dissertations

Rapid scan electron paramagnetic resonance (EPR) was developed in the Eaton laboratory at the University of Denver. Applications of rapid scan to wider spectra, such as for immobilized nitroxides, spin-labeled proteins, irradiated tooth and fingernail samples were demonstrated in this dissertation. The scan width has been increased from 55 G to 160 G. The signal to noise (S/N) improvement for slowly tumbling spin-labeled protein samples that is provided by rapid scan EPR will be highly advantageous for biophysical studies. With substantial improvement in S/N by rapid scan, the dose estimation for irradiated tooth enamels became more reliable than …

Statistical Modeling Of Microrna Expression With Human Cancers, Ke-Sheng Wang, Yue Pan, Chun Xu

Health & Biomedical Sciences Faculty Publications and Presentations

MicroRNAs (miRNAs) are small non-coding RNAs (containing about 22 nucleotides) that regulate gene expression. MiRNAs are involved in many different biological processes such as cell proliferation, differentiation, apoptosis, fat metabolism, and human cancer genes; while miRNAs may function as candidates for diagnostic and prognostic biomarkers and predictors of drug response. This paper emphasizes the statistical methods in the analysis of the associations of miRNA gene expression with human cancers and related clinical phenotypes: 1) simple statistical methods include chi-square test, correlation analysis, t-test and one-way ANOVA; 2) regression models include linear and logistic regression; 3) survival analysis approaches such as …

Collective Phenomena In Active Systems, Xingbo Yang

Dissertations - ALL

This dissertation investigates collective phenomena in active systems of biological relavance across length scales, ranging from intracellular actin systems to bird flocks. The study has been conducted via theoretical modeling and computer simulations using tools from soft condensed matter physics and non-equilibrium statistical mechanics. The work has been organized into two parts through five chapters. In part one (chapter 2 to 3), continuum theories have been utilized to study pattern formation in bacteria suspensions, actomyosin systems and bird flocks, whose dynamics is described generically within the framework of polar active fluids. The continuum field equations have been written down phenomenogically …

Controlling Microbial Multicellular Behaviors With Saccharide Derivatives, Nischal Singh

Dissertations - ALL

Microbial multicellular behaviors like biofilm formation and swarming motility are known to increase their tolerance against antimicrobials. From microbial standpoint, nonmicrobicidal agents that do not impede growth are tolerable and therefore, there is a lower propensity to develop resistance against such agents as compared to microbicidal ones (antibiotics). This study describes a new antibiofilm approach of using nonmicrobicidal saccharide derivatives for controlling the multicellular behaviors of gram-negative bacteria, Pseudomonas aeruginosa and fungus, Candida albicans.

Pseudomonas aeruginosa is known to secrete rhamnolipids, a class of biosurfactants that plays an important role in maintaining the architecture of its biofilm and promoting its …

Measurements Of Population Densities Of Metastable And Resonant Levels Of Argon Using Laser Induced Fluorescence, M. Nikolic, J. Newton, C. I. Sukenik, L. Vuskovic, S. Popovic

Physics Faculty Publications

We present a new approach to measure population densities of Ar I metastable and resonant excited states in low temperature Ar plasmas at pressures higher than 1 Torr. This approach combines the time resolved laser induced fluorescence technique with the kinetic model of Ar. The kinetic model of Ar is based on calculating the population rates of metastable and resonant levels by including contributions from the processes that affect population densities of Ar I excited states. In particular, we included collisional quenching processes between atoms in the ground state and excited states, since we are investigating plasma at higher pressures. …

Cross Sections For The Exclusive Photon Electroproduction On The Proton And Generalized Parton Distributions, H. S. Jo, D. Adikaram, M. J. Amaryan, L. El Fassi, N. Guler, A. Klein, S E. Kuhn, Y. Prok, L. B. Weinstein, J. Zhang, Z. W. Zhao

Physics Faculty Publications

Unpolarized and beam-polarized fourfold cross sections (d⁴σ/dQ²dx_Bdtdϕ) for the ep → e'p'γ reaction were measured using the CLAS detector and the 5.75-GeV polarized electron beam of the Jefferson Lab accelerator, for 110 (Q²;x_B;t) bins over the widest phase space ever explored in the valence-quark region. Several models of generalized parton distributions (GPDs) describe the data well at most of our kinematics. This increases our confidence that we understand the GPD H, expected to be the dominant contributor to these observables. Through a leading-twist …

Effects Of Plasma Processing On Secondary Electron Yield Of Niobium Samples, M. Basovic, S. Popovic, M. Tomovic, L. Vuskovic, A. Samolov, F. Cuckov

Physics Faculty Publications

Impurities deposited on the surface of Nb during both the forming and welding of accelerator cavities add to the imperfections of the sheet metal, which then affects the overall performance of the cavities. This leads to a drop in the Q factor and limits the maximum acceleration gradient achievable per unit length of the cavities. The performance can be improved either by adjusting the fabrication and preparation parameters, or by mitigating the effects of fabrication and preparation techniques used. We have developed the experimental setup to determine Secondary Electron Yield (SEY) from the surface of Nb samples. Our aim is …

New La-Icp-Ms U-Pb Zircon Dating For Strandja Granitoids (Se Bulgaria): Evidence For Two-Stage Late Variscan Magmatism In The Internal Balkanides, Philip Machev, Valentin Ganev, Laslo Klain

Turkish Journal of Earth Sciences

The Strandja Massif (Sakar-Strandja Zone) forms an important link between the Balkan Zone (external Balkanides) of Bulgaria, which is commonly correlated with the Variscan orogen in Central Europe, and the Western Pontides of Turkey. The Bulgarian part of the massif is composed of a metamorphic basement (various granite gneisses, paragneisses, and schists) traditionally interpreted as having Precambrian age, Triassic-Jurassic metasedimentary cover, and Upper Cretaceous volcanosedimentary sequences. The basement is intruded by large granitic plutons of Variscan age that are widespread mostly across Turkish territory. New LA-ICP-MS data support the suggestion of Variscan granitoid magmatism in the studied area but do …

Clay Mineralogy, Chemistry, And Diagenesis Of Late Devonian K-Bentonite Occurrences In Northwestern Turkey, Asuman Günal Türkmenoğlu, Ömer Bozkaya, Mehmet Cemal Göncüoğlu, Özge Ünlüce, İsmai̇l Ömer Yilmaz, Cengi̇z Okuyucu

Turkish Journal of Earth Sciences

Thin beds of tephra (K-bentonites) formed by the diagenesis of volcanic ash are exposed within the limestone-dolomitic limestone successions of the Yılanlı formation at Zonguldak and Bartın in northwestern Turkey. They were deposited on the Middle Devonian-Lower Carboniferous shallow carbonate platform of the Zonguldak terrane. In this study, K-bentonite samples collected from Gavurpınarı and Yılanlı Burnu limestone quarries are investigated in order to reveal their mineralogical and geochemical characteristics and diagenetic evolution. Illite is the major clay mineral in the studied K-bentonites. Additionally, kaolinite and mixed-layer illite-smectite are identified in some samples. The nonclay minerals calcite, dolomite, quartz, gypsum, feldspar, …

Nature And Physicochemical Conditions Of Crystallization In The South Dehgolan Intrusion, Nw Iran: Mineral-Chemical Evidence, Fatemeh Sarjoughian, Ali Kananian, David Richard Lentz, Jamshid Ahmadian

Turkish Journal of Earth Sciences

The South Dehgolan intrusion in the Sanandaj-Sirjan Zone ranges in composition from calc-alkalic monzogabbro to syenite to alkalic granite. This suite is composed mainly of variable proportions of quartz, K-feldspar, plagioclase, biotite, hornblende, and pyroxene. The plagioclase composition varies between albite to labradorite. The biotites are Mg- to Fe-rich in the monzogabbro to granite, respectively. The amphiboles are calcic and the composition varies from magnesiohornblende to actinolite. Clinopyroxene compositions fall in the diopside-augite field. The average calculated near-solidus crystallization temperatures are 774 °C, 655 °C, and 775 °C for the monzogabbro-monzodiorite, syenite, and granite, respectively. Calculated average pressures of emplacement …

Petrography And Geochemistry Of The Kamlial Formation, Southwestern Kohat Plateau, Pakistan: Implications For Paleoclimate Of The Western Himalayas, Kafayat Ullah, Mohammad Arif, Muhammad Tahir Shah

Turkish Journal of Earth Sciences

The Middle to Late Miocene Kamlial Formation that largely consists of sandstone and interbedded clay/mudstone sequences is exposed in the southwestern part of the Kohat plateau, which constitutes the westernmost extension of the Himalayan Foreland Basin. Whereas the sandstone is gray to brownish gray, fine- to medium-grained, and mostly thick-bedded, the interbedded clay/mudstone sequence is brownish gray to maroon red and occurs as continuous beds as well as lenses. Some mudstone/clay beds are bioturbated and seem to be pedogenic surfaces. Results of geochemical investigation of fresh (unaltered) representative sandstone and mudstone samples from three different sections of the formation in …

Spatial-Temporal Analysis Of Seismicity Before The 2012 Varzeghan, Iran, Mw 6.5 Earthquake, Mohammad Talebi, Mehdi Zare, Rohollah Madahi Zadeh, Aref Bali-Lashak

Turkish Journal of Earth Sciences

In this work, the spatial and temporal variations of seismicity in northwestern Iran have been evaluated with a special focus on seismic precursors of the 11 August 2012 Mw 6.5 Varzeghan earthquake. The precursors are defined by the z-value test and the generalized fractal dimensions of earthquake epicenters. The investigation applies earthquakes that have occurred since 2006 in a region that includes the main shock and collected by the Iranian Seismological Center. In order to eliminate the effect of explosions in the processing, we removed the explosion from the used catalog by using the normalized ratio analysis of daytime to …

Lower Devonian Trace Fossils And Their Paleoenvironmental Significance From The Western Yangtze Plate, South China, Li-Jun Zhang, Zhao Zhao

Turkish Journal of Earth Sciences

Abundant and diverse trace fossils occur in the littoral-neritic sediments recording an Early Devonian transgression in South China. The well-exposed Ganxi section is located in the Longmen Mountain 100 km northwest of Chendu, Sichuan. The Lower Devonian strata are dominated by sandstones, siltstones, muddy shales, limestones, bioclastic limestones, and muddy limestones. About thirteen ichnogenera were systematically described, including Arenicolites, ?Balanoglossites, Chondrites, Cylindrichnus, Diplocraterion, Planolites, Palaeophycus, Phycodes, Rhizocorallium, Rusophycus, Skolithos, Thalassinoides, and Zoophycos. Six trace fossil associations under different sedimentary environments have been recognized as follows: the Skolithos and Diplocraterion-Skolithos associations mainly consist of domichnia derived from a high-energy zone of …

Rare Earth Element Geochemistry Of The Upper Permian Limestone: The Kanigorgeh Mining District, Nw Iran, Ali Abedini, Ali Asghar Calagari

Turkish Journal of Earth Sciences

The limestone of the Ruteh Formation of Upper Permian age in the Kanigorgeh district (northeast of Bukan, NW Iran) contains several layers and lenses of bauxitic ores. Mineralogical data show that this limestone consists of calcite and quartz as major and plagioclase, kaolinite, and hematite as minor mineral phases. Geochemical analyses reveal that the proportions of ?REEs (La-Lu) in this limestone vary from 35.28 to 160.78 ppm. The values of Eu and Ce anomalies (normalized to PAAS) of the limestone have ranges of 1.11-1.68 and 0.89-1.16, respectively. The high values of ?REEs; low values of Y/Ho; strong and positive correlations …

Petrography And Geochemistry Of Pharaonic Sandstone Monuments In Tall San Al Hagr, Al Sharqiya Governorate, Egypt: Implications For Provenance And Tectonic Setting, Samir Mahmoud Zaid, Oussama El Badry, Fatma Ramadan, Mahmoud Mohamed

Turkish Journal of Earth Sciences

Petrographic and major and trace element compositions of Tanis sandstones from Tall San Al Hagr, Al Sharqiya Governorate, Egypt, have been investigated to determine their source, provenance, intensity of paleoweathering of the source rocks, and tectonic setting. Tanis sandstones are yellowish brown in color, siliceous, partly calcareous, and originated from sands deposited in fluvial channels. Texturally, Tanis sandstones are medium- to very coarse-grained, mature, and moderately sorted. Scarcity of feldspars indicates that the sandstone is extensively recycled from a distant source. Their average modal composition (Q99.75F0.03L0.22) classifies them as quartz arenites (quartzite), which is consistent with the geochemical study. Chemical …

Petrography And Palynology Of Late Oligocene And Middle Miocene Coals In The Gelibolu Peninsula, Nw Turkey, Ferdi̇ Demi̇rtaş, Mustafa Bozcu, Erdal Koşun, Mehmet Serkan Akki̇raz

Turkish Journal of Earth Sciences

In this study, coal samples from two different coal zones located close to each other were examined. They occur in the Late Oligocene Osmancık and Miocene Gazhanedere formations in the Gelibolu peninsula, in the SW part of the Thrace Basin (NW Turkey). This paper focuses on the organic-petrographic composition and depositional conditions of the two coal zones by using coal petrography, including maceral ratios, and palynology. The maceral composition of the Oligocene coal samples is similar to that of the Miocene coal samples. The coal samples from both locations are characterized by a high content of huminite group macerals, ranging …

Dual Targeted Immunotherapy Via In Vivo Delivery Of Bio-Hybrid Rnai-Peptide Nanoparticles To Tumour-Associated Macrophages And Cancer Cells, Joao Conde, Chenchen Bao, Yeqi Tan, Daxiang Cui, Elazier Edelman, Helena Azevedo, Hugh Byrne, Natalie Artzi, Furong Tian

Articles

Lung cancer is associated with very poor prognosis and considered one of the leading causes of death worldwide. Here, we present highly potent and selective bio-hybrid RNAi-peptide nanoparticles that can induce specific and long-lasting gene therapy in inflammatory tumour associated macrophages (TAMs), via an immune modulation of the tumour milieu combined with tumour suppressor effects. Our data prove that passive gene silencing can be achieved in cancer cells using regular RNAi NPs. When combined with M2 peptide-based targeted immunotherapy that immuno-modulates TAMs cell-population, a synergistic effect and long-lived tumour eradication can be observed along with increased mice survival. Treatment with …

Honors Research, Sarah Page, Daniel Lowes, Gabe Moore, Weelic Chong

The Synapse: Intercollegiate science magazine

No abstract provided.

Undue Coercion Or Societal Neccessity?, Emilia Verrone

The Synapse: Intercollegiate science magazine

No abstract provided.

Field Notes From The Climate, Stephen Lezak

The Synapse: Intercollegiate science magazine

No abstract provided.

Are We Entering A Post-Antibiotic Era? Tracking The Rise Of The Superbug, Tara Santora

The Synapse: Intercollegiate science magazine

No abstract provided.

Design, Synthesis, And Pharmacological Evaluation Of Three Series Of Lobelane Analogs As Inhibitors Of The Vesicular Monoamine Transporter (Vmat2), John P. Culver

Theses and Dissertations--Pharmacy

Methamphetamine (METH) abuse is a serious problem in the United States and worldwide. The reward experienced by METH users is due to the increase in extracellular dopamine (DA) concentrations caused by an interaction between METH and the DA transporter (DAT) as well as the Vesicular Monoamine Transporter-2 (VMAT2). The reward felt by users of METH leads to further use of the drug and subsequent abuse. The current project examined the ability of three novel series of lobelane analogs to interact with a binding site on the Vesicular Monoamine Transporter-2 (VMAT2) in an attempt to inhibit the effects of METH. Lobelane …

Multi-Satellite Formation Trajectory Design With Topological Constraints Over A Region Of Interest Using Differential Evolution, David William Hinckley

Graduate College Dissertations and Theses

Satellite formation missions allow for scientific measurement opportunities that are only otherwise possible with the use of unrealistically large satellites. This work applies the Evolutionary Algorithm (EA), Differential Evolution (DE), to a 4-satellite mission design that borrows heavily from the mission specifications for Phase 1 of NASA's Magnetospheric Multi-Scale Mission (MMS). This mission specifies goals for formation "quality" and size over the arc when scientific measurements are to be taken known as the Region of Interest (ROI). To apply DE to this problem a novel definition of fitness is developed and tailored to trajectory problems of the parameter scales of …

An Evaluation Of Vermicompost As A Fast-Acting Nitrogen Amendment To Mitigate Nitrogen Deficiencies In Organic Vegetable Production, Peter Dalton Austin

Graduate College Dissertations and Theses

For sustained production, organic agriculture depends on plant needs being synchronized with the release of nutrients from organic amendments during decomposition within the soil. Because decomposition is strongly dependent on soil moisture and temperature, nutrient needs may not always be met as planned or synchronous with plant need. Unlike conventional agriculture, fast acting amendments are not readily available. Much of the evidence that vermicompost benefits crop production comes from studies on seed germination and production of starts in greenhouses. Yet, there is a dearth of information derived from field studies. Soil, soil and water nitrogen, plant development, and marketable yield …