Physical Sciences and Mathematics Commons^™

The Autophagy-Related Beclin-1 Protein Requires The Coiled-Coil And Bara Domains To Form A Homodimer With Submicromolar Affinity, Matthew J. Ranaghan, Michael A. Durney, Michael F. Mesleh, Patrick R. Mccarren, Colin W. Garvie, Douglas S. Daniels, Kimberly L. Carey, Adam P. Skepner, Beth Levine, Jose R. Perez

Chemistry Faculty Publications

Beclin-1 (BECN1) is an essential component of macroautophagy. This process is a highly conserved survival mechanism that recycles damaged cellular components or pathogens by encasing them in a bilayer vesicle that fuses with a lysosome to allow degradation of the vesicular contents. Mutations or altered expression profiles of BECN1 have been linked to various cancers and neurodegenerative diseases. Viruses, including HIV and herpes simplex virus 1 (HSV-1), are also known to specifically target BECN1 as a means of evading host defense mechanisms. Autophagy is regulated by the interaction between BECN1 and Bcl-2, a pro-survival protein in the apoptotic pathway that …

Reef Fish Assemblage Biogeography Along The Florida Reef Tract, Cory Ames

HCNSO Student Theses and Dissertations

Understanding the biogeography of reef fish assemblages is paramount to reef conservation, management, and conducting appropriate population survey designs. Reef fish assemblages are a multispecies complex of reef-associated fish and are shaped by multiple environmental and biological factors (e.g. temperature, depth, benthic habitat, and topographic relief), which determine the species constituents residing in an area. Assemblages typically change with latitude where the number of families, genera, and/or densities of species specific to warmer climates decrease poleward into colder climate regimes. The Florida Reef Tract (FRT) extends for 595 km from the Dry Tortugas in the south-west to Martin County in …

A Geophysical Investigation Of Stratigraphy And Structure On St. Catherines Island, Georgia, Anne M. Delua

Honors College Theses

Geophysical tools were used to investigate potential structural and stratigraphic pathways of the salt water intrusion that is affecting the surficial aquifer on St. Catherines Island, Georgia. Ground penetrating radar (GPR) is a geophysical tool that uses electromagnetic waves to view the subsurface. GPR is used for a variety of applications stratigraphically, biologically, and anthropogenically. GPR electromagnetic waves react to changes in density and composition and type and percentage of pore fluids in sediment and rock. GPR waves also react to interfaces including fractures and faults. GPR waves exhibit attenuation and decreased return signal in materials such as clay. Fresh …

Infinite-Dimensional Measure Spaces And Frame Analysis, Palle Jorgensen, Myung-Sin Song

SIUE Faculty Research, Scholarship, and Creative Activity

We study certain infinite-dimensional probability measures in connection with frame analysis. Earlier work on frame-measures has so far focused on the case of finite-dimensional frames. We point out that there are good reasons for a sharp distinction between stochastic analysis involving frames in finite vs. infinite dimensions. For the case of infinite-dimensional Hilbert space ℋ, we study three cases of measures. We first show that, for ℋ infinite dimensional, one must resort to infinite dimensional measure spaces which properly contain ℋ. The three cases we consider are: (i) Gaussian frame measures, (ii) Markov path-space measures, and (iii) determinantal measures.

Search For High-Energy Neutrinos From Binary Neutron Star Merger Gw170817 With Antares, Icecube, And The Pierre Auger Observatory, Antares Collaboration, The Icecube Collaboration, The Pierre Auger Collaboration, Ligo Scientific Collaboration, Virgo Collaboration, Karen Andeen

Physics Faculty Research and Publications

The Advanced LIGO and Advanced Virgo observatories recently discovered gravitational waves from a binary neutron star inspiral. A short gamma-ray burst (GRB) that followed the merger of this binary was also recorded by the FermiGamma-ray Burst Monitor (Fermi-GBM), and the Anti-Coincidence Shield for the Spectrometer for the International Gamma-Ray Astrophysics Laboratory(INTEGRAL), indicating particle acceleration by the source. The precise location of the event was determined by optical detections of emission following the merger. We searched for high-energy neutrinos from the merger in the GeV–EeV energy range using the Antares, IceCube, and Pierre Auger Observatories. …

De Paepe, Duane - Collector (Mss 625), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid only for Manuscripts Collection 625. The Duane De Paepe Kentucky Cave Saltpetre History Research Collection, a collection of historical research, field notes, cave surveys, photographs, maps, reports, and scholarly writing on saltpetre mining in Kentucky, especially at Mammoth Cave. The collection was created under a research program sponsored by the Cave Research Foundation and the National Geographic Society in Kentucky, 1976-1980, and directed by De Paepe.

Investigation Of Sediment Ridges Using Bathymetry And Backscatter Near Clearwater, Florida, Lewis Stewart

USF Tampa Graduate Theses and Dissertations

Changes in sediment morphology on the West Florida Shelf is investigated over a 14-year time period using multibeam bathymetry and backscatter in water depths between 10 m and 20 m, off the coast of Indian Rocks Beach, Pinellas County, Florida. Bathymetric surveys collected in 2002 (Kongsberg EM 3000 at 300 kHz) and 2016 (Reson 7125 at 400 kHz) were processed using CARIS Hips and Sips to create bathymetric maps and backscatter images. These data were then interpreted and compared in order to test hypotheses and answer questions related to sediment migration and sediment volume change.

The following questions prompted this …

Substituted Hydroxylamines As Nitrogen Transfer Reagents: Direct Synthetic Pathways To Structurally Rich Heteroatomic Scaffolds, Dylan John Quinn

Theses and Dissertations

Nitrogen is found in virtually all valuable chemical compounds. The abundance of atmospheric nitrogen however, is rendered inaccessible because of the strong N-N triple bond, ultimately preventing its practical utilization in synthetic organic synthesis. The development of powerful nitrogen transfer reagents, such as substituted hydroxylamine derivatives, have played an important role in the introduction of nitrogen into valuable chemical scaffolding.

Herein is reported the methodological development of synthetic nitrogen placement into a range of valuable heteroatomic compounds. This work shows that O-Substituted Hydroxylamine can be used to furnish small heteroatomic compounds, particularly nitriles. Whereas, N-Substituted Hydroxylamine can be employed to …

Frontline Experiences From Changing Fisheries Bycatch Paradigms, David Kerstetter

Marine & Environmental Sciences Faculty Proceedings, Presentations, Speeches, Lectures

No abstract provided.

Self-Assembled Monolayers And Methods For Using The Same In Biosensing Applications, Patrick Dussault, Rebecca Lai, Thomas J. Fisher, Anita J. Zaitouna

Patrick Dussault Publications

Cross - linked amphiphile constructs that form self - as sembled monolayers ( SAMs ) on metal surfaces such as gold surfaces are disclosed . These new SAMs generate well packed and highly oriented monolayer films on gold sur faces . A method for using the SAMs in the fabrication of biomolecule sensors is also disclosed .

Snow Accumulation Variability Over The West Antarctic Ice Sheet Since 1900: A Comparison Of Ice Core Records With Era‐20c Reanalysis, Yetang Wang, Elizabeth R. Thomas, Shugui Hou, Baojuan Huai, Shuang-Ye Wu, Weijun Sun, Shanzhong Qi, Minghu Ding, Yulun Zhang

Geology Faculty Publications

This study uses a set of 37 firn core records over the West Antarctic Ice Sheet (WAIS) to test the performance of the twentieth century from the European Centre for Medium‐Range Weather Forecasts (ERA‐20C) reanalysis for snow accumulation and quantify temporal variability in snow accumulation since 1900. The firn cores are allocated to four geographical areas demarcated by drainage divides (i.e., Antarctic Peninsula (AP), western WAIS, central WAIS, and eastern WAIS) to calculate stacked records of regional snow accumulation. Our results show that the interannual variability in ERA‐20C precipitation minus evaporation (P − E) agrees well with the corresponding ice …

Feasibility Of Using Virtual Reality In Requirements Elicitation Process, Aman Bhimani

Master of Science in Software Engineering Theses

Contemporary Virtual Reality (VR) technologies offer an increasing number of functionalities including head-mounted displays (HMD), haptic and sound feedback, as well as motion tracking. This gives us the opportunity to leverage the immersive power offered by these technologies in the context of requirements elicitation, especially to surface those requirements that cannot be expressed via traditional techniques such as interviews and focus groups. The goal of this thesis is to survey uses of VR in requirements engineering, and to describe a method of elicitation using VR as a tool.

To validate the methodology, a research plan is developed with a strong …

A Churn For The Better: Localizing Censorship Using Network-Level Path Churn And Network Tomography, Shinyoung Cho, Abbas Razaghpanah, Rishab Nithyanand, Phillipa Gill

Computer Science: Faculty Publications

Recent years have seen the Internet become a key vehicle for citizens around the globe to express political opinions and organize protests. This fact has not gone unnoticed, with countries around the world repurposing network management tools (e.g., URL iltering products) and protocols (e.g., BGP, DNS) for censorship. Previous work has focused on identifying how censorship is performed. However, there is no major studies to identify, at a global scale, the networks responsible for performing censorship. Also, repurposing network products for censorship can have unintended international impact, which we refer to as lcensorship leakagež. While there have been anecdotal reports …

Early Neolithic Wine Of Georgia In The South Caucasus, Michael P. Callahan, Karen E. Smith

Chemistry and Biochemistry Faculty Publications and Presentations

Chemical analyses of ancient organic compounds absorbed into the pottery fabrics from sites in Georgia in the South Caucasus region, dating to the early Neolithic period (ca. 6,000–5,000 BC), provide the earliest biomolecular archaeological evidence for grape wine and viniculture from the Near East, at ca. 6,000–5,800 BC. The chemical findings are corroborated by climatic and environmental reconstruction, together with archaeobotanical evidence, including grape pollen, starch, and epidermal remains associated with a jar of similar type and date. The very large-capacity jars, some of the earliest pottery made in the Near East, probably served as combination fermentation, aging, and serving …

Spatially Explicit Model Of Areas Between Suitable Black Bear Habitat In East Texas And Black Bear Populations In Louisiana, Arkansas, And Oklahoma, Caitlin M. Glymph, Christopher Comer, Daniel Scognamillo, Daniel Unger, Yanli Zhang

Electronic Theses and Dissertations

Although black bears (Ursus americanus, Ursus americanus luteolus) were once found throughout the south-central United States, unregulated harvest and habitat loss resulted in severe range retractions and by the beginning of the twentieth century populations in Oklahoma, Louisiana, Texas and Arkansas were nearing extirpation. In response to these losses, translocation programs were initiated in Arkansas (1958-1968 & 2000-2006) and Louisiana (1964-1967 & 2001-2009). These programs successfully restored bears to portions of Louisiana and Arkansas, and, as populations in Arkansas began dispersing, to Oklahoma. In contrast, east Texas remains unoccupied despite the existence of suitable habitat in the region.

To facilitate …

The Pulsed Electro-Acoustic Method, Zack Gibson

Physics Student Research

A Pulsed Electro-Acoustic (PEA) system has been developed and is being used to study electron charge injection, transport, and relaxation in highly disordered insulating materials. The material is placed between two electrodes in a parallel plate configuration. The sample is injected with charge via electrode charging by applying a high voltage across the sample. The distribution of charge in the dielectric is measured with PEA by applying a ~100 MHz ~850 V electric pulse to displace the embedded charge, causing an acoustic pulse monitored via time-of-flight with a thin piezoelectric sensor allowing observation of charge accumulation and dissipation. Measurements of …

The Graph Database: Jack Of All Trades Or Just Not Sql?, George F. Hurlburt, Maria R. Lee, George K. Thiruvathukal

Computer Science: Faculty Publications and Other Works

This special issue of IT Professional focuses on the graph database. The graph database, a relatively new phenomenon, is well suited to the burgeoning information era in which we are increasingly becoming immersed. Here, the guest editors briefly explain how a graph database works, its relation to the relational database management system (RDBMS), and its quantitative and qualitative pros and cons, including how graph databases can be harnessed in a hybrid environment. They also survey the excellent articles submitted for this special issue.

Biotime: A Database Of Biodiversity Time Series For The Anthropocene, Maria Dornelas, Laura H. Antao, Faye Moyes, Amanda E. Bates, William A. Gould, L. Donald, Edward Castaneda-Moya

FCE LTER Journal Articles

No abstract provided.

A Prograding Margin During Global Sea-Level Maxima: An Example From Mahajanga Basin, Northwest Madagascar, Jonathan Obrist-Farner, Philip J. Ball, Thomas A. (Mac) Mcgilvery, Raymond R. Rogers

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

The Mesozoic shelf margin in the Mahajanga Basin, northwest Madagascar, provides an example where inherited palaeobathymetry, coupled with sea-level changes, high sediment supply and fluctuations in accommodation influenced the stacking patterns and geometry of clinoforms that accreted onto a passive rifted margin. Two-dimensional (2D) seismic profiles are integrated with existing field data and geological maps to study the evolution of the margin. The basin contains complete records of transgression, highstand, regression and lowstand phases that took place from Jurassic to Cretaceous. Of particular interest is the Cretaceous, Albian to Turonian (ca. 113-93 Ma), siliciclastic shelf margin that prograded …

Phenology Largely Explains Taller Grass At Successful Nests In Greater Sage-Grouse, Joseph T. Smith, Jason D. Tack, Kevin Doherty, Brady W. Allred, Jeremy D. Maestas, Lorelle I. Berkeley, Seth J. Dettenmaier, Terry A. Messmer, David E. Naugle

Wildland Resources Faculty Publications

Much interest lies in the identification of manageable habitat variables that affect key vital rates for species of concern. For ground-nesting birds, vegetation surrounding the nest may play an important role in mediating nest success by providing concealment from predators. Height of grasses surrounding the nest is thought to be a driver of nest survival in greater sage-grouse (Centrocercus urophasianus; sage-grouse), a species that has experienced widespread population declines throughout their range. However, a growing body of the literature has found that widely used field methods can produce misleading inference on the relationship between grass height and nest success. Specifically, …

Challenges In Characterizing The Environmental Fate And Effects Of Carbon Nanotubes And Inorganic Nanomaterials In Aquatic Systems, Peter Laux, Christian Riebeling, Andy M. Booth, Joseph D. Brain, Josephine Brunner, Cristina Cerrillo, Otto Creutzenberg, Irina Estrela-Lopis, Thomas Gebel, Gunnar Johanson, Harald Jungnickel, Heiko Kock, Jutta Tentschert, Ahmed Tlili, Andreas Schäffer, Adriënne J. A. M. Sips, Robert A. Yokel, Andreas Luch

Pharmaceutical Sciences Faculty Publications

The current lack of commonly used protocols for dispersion, characterization, and aquatic toxicity testing of nanomaterials (NMs) has resulted in inconsistent results, which make meaningful comparisons difficult. The need for standardized sample preparation procedures that allow the reproducible generation of relevant test conditions remains a key challenge for studies of the environmental fate and aquatic toxicity of NMs. Together with the further development of optimized and cost-effective analytical techniques for physicochemical characterization that depend on reproducible sample preparation, such methods have the potential to overcome the current uncertainties with regard to NM dispersion properties, effective dose, and particle dissolution. In …

Time Series Analysis Of Surface Deformation Associated With Fluid Injection And Induced Seismicity In Timpson, Texas Using Dinsar Methods, Simon Thorpe

Electronic Thesis and Dissertation Repository

In recent years, a rise in unconventional oil and gas production in North America has been linked to an increase in seismicity rate in these regions (Ellsworth, 2013). As fluid is pumped into deep formations, the state of stress within the subsurface changes, potentially reactivating pre-existing faults and/or causing subsidence or uplift of the surface. Therefore, hydraulic fracturing and/or fluid disposal injection can significantly increase the seismic hazard to communities and structures surrounding the injection sites (Barnhart et al., 2014). On 17th May 2012 an Mw4.8 earthquake occurred near Timpson, TX and has been linked with wastewater injection operations in …

Geophysical Study Of Complex Meteorite Impact Structures, William Zylberman

Electronic Thesis and Dissertation Repository

Hypervelocity impact craters are the most abundant morphologic features on rocky planetary bodies of the Solar System, except on Earth where they have mostly been erased by plate tectonics, erosion, or are buried under sediments. The internal structure of complex impact craters can only be studied on Earth by using ground-truth geophysical and geological studies. Such approaches - combined with modeling - can reveal how impact cratering, target geological composition, erosion and other post-impact processes can lead to the observed geophysical anomalies, which could also be detected by remote geophysical data on other planetary surfaces. In this work, a multidisciplinary …

Determination Of The Absorption Coefficient Of Chromophoric Dissolved Organic Matter From Underway Spectrophotometry, Giorgio Dall’Olmo, Robert J. W. Brewin, Francesco Nencioli, Emanuele Organelli, Ina Lefering, David Mckee, Rüdiger Röttgers, Catherine Mitchell, Emmanuel Boss, Annick Bricaud, Gavin Tilstone

Marine Sciences Faculty Scholarship

Measurements of the absorption coefficient of chromophoric dissolved organic matter (ay) are needed to validate existing ocean-color algorithms. In the surface open ocean, these measurements are challenging because of low ay values. Yet, existing global datasets demonstrate that ay could contribute between 30% to 50% of the total absorption budget in the 400-450 nm spectral range, thus making accurate measurement of ay essential to constrain these uncertainties. In this study, we present a simple way of determining ay using a commercially-available in-situ spectrophotometer operated in underway mode. The obtained ay values were validated using independent collocated measurements. The method is …

Sampling Effort And Uncertainty In Leaf Litterfall Mass And Nutrient Flux In Northern Hardwood Forests, Yang Yang, Ruth D. Yanai, Craig R. See, Mary A. Arthur

Forestry and Natural Resources Faculty Publications

Designs for litterfall sampling can be improved by understanding the sources of uncertainty in litterfall mass and nutrient concentration. We compared the coefficient of variation of leaf litterfall mass and nutrient concentrations (nitrogen, phosphorus, calcium, magnesium, and potassium) at different spatial scales and across years for six northern hardwood species from 23 stands in the White Mountains of New Hampshire, USA. Stands with steeper slopes (P = 0.01), higher elevations (P = 0.05), and more westerly aspect (P = 0.002) had higher interannual variation in litter mass, probably due to a litter trap design that allowed litter …

Applying Topographic Classification, Based On The Hydrological Process, To Design Habitat Linkages For Climate Change, Yongwon Mo, Dong Kun Lee, Keunyea Song, Ho Gul Kim, Soo Jin Park

School of Natural Resources: Faculty Publications

The use of biodiversity surrogates has been discussed in the context of designing habitat linkages to support the migration of species affected by climate change. Topography has been proposed as a useful surrogate in the coarse-filter approach, as the hydrological process caused by topography such as erosion and accumulation is the basis of ecological processes. However, some studies that have designed topographic linkages as habitat linkages, so far have focused much on the shape of the topography (morphometric topographic classification) with little emphasis on the hydrological processes (generic topographic classification) to find such topographic linkages. We aimed to understand whether …

In Place: November 27, 2017, Place

PLACE Historical Documents

In PLACE is a newsletter designed to keep the Linfield College community apprised of information related to PLACE activities, as well as ways to bring the program into classes. Included in this issue:

• Spotlight On: "What's the Big Idea"
• Upcoming Events
• PLACE in the News

Mode-Sum Prescription For Vacuum Polarization In Black Hole Spacetimes In Even Dimensions, Peter Taylor, Cormac Doran

Articles

We present a mode-sum regularization prescription for computing the vacuum polarization of a scalar field in static spherically symmetric black hole spacetimes in even dimensions. This is the first general and systematic approach to regularized vacuum polarization in higher even dimensions, building upon a previous scheme we developed for odd dimensions. Things are more complicated here since the even-dimensional propagator possesses logarithmic singularities which must be regularized. However, in spite of this complication, the regularization parameters can be computed in closed form in arbitrary even dimensions and for arbitrary metric function f(r). As an explicit example of our method, we …

Biases In Metallicity Measurements From Global Galaxy Spectra: The Effects Of Flux Weighting And Diffuse Ionized Gas Contamination, Ryan L. L. Sanders, Alice E. Shapley, Kai Zhang, Renbin Yan

Physics and Astronomy Faculty Publications

Galaxy metallicity scaling relations provide a powerful tool for understanding galaxy evolution, but obtaining unbiased global galaxy gas-phase oxygen abundances requires proper treatment of the various line-emitting sources within spectroscopic apertures. We present a model framework that treats galaxies as ensembles of H II and diffuse ionized gas (DIG) regions of varying metallicities. These models are based upon empirical relations between line ratios and electron temperature for H II regions, and DIG strong-line ratio relations from SDSS-IV MaNGA IFU data. Flux-weighting effects and DIG contamination can significantly affect properties inferred from global galaxy spectra, biasing metallicity estimates by more than …

Compton Scattering From 4He At 61 Mev, M. H. Sikora, M. W. Ahmed, A. Banu, C. Bartram, B. Crowe, E. J. Downie, G. Feldman, H. Gao, H. W. Grießhammer, H. Hao, C. R. Howell, H. J. Karwowski, D. P. Kendellen, Michael A. Kovash, X. Li, D. M. Markoff, S. Mikhailov, V. Popov, R. E. Pywell, J. A. Silano, M. C. Spraker, P. Wallace, H. R. Weller, C. S. Whisnant, Y. K. Wu, W. Xiong, X. Yan, Z. W. Zhao

Physics and Astronomy Faculty Publications

The Compton scattering cross section from ⁴He has been measured with high statistical accuracy over a scattering angle range of 40^∘−159^∘ using a quasimonoenergetic 61-MeV photon beam at the High Intensity Gamma-Ray Source. The data are interpreted using a phenomenological model sensitive to the dipole isoscalar electromagnetic polarizabilities (α_s and β_s) of the nucleon. These data can be fit with the model using values of α_s and β_s that are consistent with the currently accepted values. These data will serve as benchmarks of future calculations from effective field theories and …