Physical Sciences and Mathematics Commons^™

The Chemistry Of The Flint Water Crisis, Ernest M. Oleksy

The Downtown Review

Politics and science do not always go hand-in-hand. Nowhere was this more clear than in the Flint Water Crisis. Negligence towards growing levels of lead poisoning in drinking water led to incredibly deleterious effects on Flint's citizens. The chemistry of equilibrium and the shortcomings of local leaders led to Flint's water becoming a crisis.

Bonding Theatre And Chemistry: An Educational Exploration, Matthew Gurniak

Senior Honors Projects, 2010-2019

This paper analyzes the educational aspects of theatre and music and the impact that they have on an audience. The goal was to begin a new conversation about science and theatre and how the two can learn and gain unique insight from each other. To examine how these two antithetical fields can interact, I composed a new, innovative musical that tells the love story between two professors through the use of concepts from general chemistry. The results and responses from the performance of the play were overwhelmingly positive from members of both disciplines. They have inspired continued interest in this …

Rapid High-Throughput Species Identification Of Botanical Material Using Direct Analysis In Real Time High Resolution Mass Spectrometry, Rabi A. Musah, Ashton D. Lesiak

Chemistry Department Faculty Scholarship

We demonstrate that direct analysis in real time-high resolution mass spectrometry can be used to produce mass spectral profiles of botanical material, and that these chemical fingerprints can be used for plant species identification. The mass spectral data can be acquired rapidly and in a high throughput manner without the need for sample extraction, derivatization or pH adjustment steps. The use of this technique bypasses challenges presented by more conventional techniques including lengthy chromatography analysis times and resource intensive methods. The high throughput capabilities of the direct analysis in real time-high resolution mass spectrometry protocol, coupled with multivariate statistical analysis …

Characterization Of S-Swcnt/Pf-Pd Dispersions And Networks, Tamara N. El-Hayek Ms., Jeffrey Blackburn, Andrew Ferguson, Tammy Pheuphong

STAR Program Research Presentations

Single-Walled Carbon Nanotubes (SWCNTs) are being investigated for their use in a wide variety of renewable energy applications. Their unique physical properties contribute to desirable traits such as a high carrier mobility, strong optical absorption and tunable electronic band gap. Unfortunately, due to variability in certain parameters, SWCNTs are limited in their application. The major drawback is that SWCNTs are variable in size and type and typical synthetic methods are not selective. As a result, selective methods must be developed in order to sort these tubes and extract those which are desirable for a particular application. Though there are several …

College Of Science And Mathematics Newsletter, Fall 2016, College Of Science And Mathematics, Wright State University

College of Science and Mathematics Newsletters

This 6 page newsletter discusses various happenings within the College of Science and Mathematics. It begins with a letter from the dean, and continues on with news, events, alumni news, and other community news.

Chemistry Department Newsletter 2016, Ken Overway

Chemistry Department Newsletters

This document contains a summary of news and events from the chemistry department from the 2015-2016 academic year.

Indigo Dying With Amy Deveau's Chemistry Class, Kim Bernard

Artist in Residence: Kim Bernard

Description and images from one of Kim Bernard's class "drop-ins" during her fall semester 2016 time as the University of New England Artist in Residence. Kim met with Professor Amy Deveau's chemistry class to integrate the process of dying with indigo into their subjects.

The Cosm Newsletter

The COSM Newsletter (2008-2018)

• Eagles in Training for STEM Careers
• The Department of Biology Welcomes New Faculty
• Biology Alumni Move Onward and Upward
• Georgia Southern's Elite 8 for REU-2016
• Geologists Investigate Salt Water Intrusion on a Georgia Barrier Island
• The Georgia Southern Sea Turtle Program at St. Catherines Island: The 2016 Sea Turtle Nesting Season
• Hatchlings
• The Department of Mathematical Sciences Welcomes New Faculty
• Eagles Win Third MacArthur Award
• Faculty member awarded new Patent on “Engineered lumenized vascular networks and support matrix”
• The Photonic Nanotechnology Computational Group
• Edwards participates in NSF "Ideas Lab" to Measure "Big G"
• Faculty Member Participates in Scholarly Activities
• Professors …

The Periodical Fall 2016, Southern Adventist University

the Periodical – Chemistry Department Newsletter

Volume 4, issue 1 of the Periodical includes articles about renovations to the Chemistry and Math departments, a chemistry professor conference, the high school forensic chemistry academic summer camp, an alumni spotlight, and a pictorial listing of December 2016 graduates.

A Direct, Early Stage Guanidinylation Protocol For The Synthesis Of Complex Aminoguanidine-Containing Natural Products, Christopher E. Malmberg, Stephen Chamberland

All Faculty Scholarship for the College of the Sciences

The guanidine functional group, displayed most prominently in the amino acid arginine, one of the fundamental building blocks of life, is an important structural element found in many complex natural products and pharmaceuticals. Owing to the continual discovery of new guanidinecontaining natural products and designed small molecules, rapid and efficient guanidinylation methods are of keen interest to synthetic and medicinal organic chemists. Because the nucleophilicity and basicity of guanidines can affect subsequent chemical transformations, traditional, indirect guanidinylation is typically pursued. Indirect methods commonly employ multiple protection steps involving a latent amine precursor, such as an azide, phthalimide, or carbamate. By …

The Subject Librarian Newsletter, Chemistry, Fall 2016, Patti Mccall

Libraries' Newsletters

No abstract provided.

A Study Of Chemistry: For Wind Ensemble, Morgan Duff

Mahurin Honors College Capstone Experience/Thesis Projects

Many musicians have a limited understanding of chemistry, while many chemists aren't familiar with details of music theory or composition. Through the composition of a four-part musical work based entirely on several broad areas of chemistry, certain relationships have been shown between music and chemistry. Because of the overlap between certain scientific concepts and many aspects of music theory, it is possible for members of both fields to use what they already know in order to gain a deeper understanding of the other, very different, subject. Because everyone has learning strengths in differing areas, I believe the use of disciplinary …

Seasonal And Spatial Variations In Chemical Composition And Fluxes Of Dissolved Organic Matter And Nutrients In The Lower Milwaukee River, Tarek A. Teber

Theses and Dissertations

Physical, chemical and biological processes directly influence the transport, composition, and fluxes of dissolved organic matter (DOM) in river watersheds. Changes in the abundance and composition of DOM and nutrients (P&N) in the watershed should reflect changes in hydrological cycle, effluent discharge, land-use and land-cover, and anthropogenic activities in the river basin, especially in rivers that run through metropolitan areas such as the Milwaukee River. Despite the importance of DOM to ecosystem health and function, a literature search to date finds no comprehensive accounting of DOM in the Milwaukee River. To examine DOM dynamics, monthly water samples were collected between …

The Function Of Renalase, Brett Allen Beaupre

Theses and Dissertations

Renalase was originally reported to be an enzyme secreted into the blood by the kidney to lower blood pressure and slow heart rate. Despite multiple reports claiming to confirm this activity in vivo there has been considerable discord in regards to the reaction catalyzed by renalase. The structural topology of renalase resembles that of known flavoprotein oxidases, monooxygenases and demethylases, but the conserved active site residues are unique to renalase. It has been reported that the catalytic function of renalase is to oxidize circulating catecholamines, however in vitro studies have failed to demonstrate a catalytic activity in the presence of …

Serendipitous Discovery Of A New Method For The Catalytic Synthesis Of Indole-Fused Benzazepanes, Edward Gluzman, Paul A. Vadola

DePaul Discoveries

We report here on our investigations into the application of 1,5-hydride transfer cyclization mechanisms to the synthesis of 2,3-disubstituted benzofurans and indoles. We found that PtI₄ in MeCN at 120 ºC was indeed capable of activating the alkyne, however, the expected 2,3-disubstituted indole product was not observed. Instead we isolated an indolyl-3-benzazepane via an unexpected intramolecular Steven’s rearrangement/ring expansion. While this transformation has been previously reported our method may prove to have increased substrate scope and more practical reaction conditions. Further studies are underway to optimize the reaction conditions and to fully explore the scope and mechanism of the …

College Of Science And Mathematics Newsletter, Summer 2016, College Of Science And Mathematics, Wright State University

College of Science and Mathematics Newsletters

This 5 page newsletter discusses various happenings within the College of Science and Mathematics. It begins with a letter from the dean, and continues on with news, events, alumni news, and other community news.

Principles Of Chemistry I (Savannah State University), Cecil Jones, Adegboye Adeyemo, Pascal Binda

Chemistry Grants Collections

This Grants Collection for Principles of Chemistry I was created under a Round Four ALG Textbook Transformation Grant. It contains materials used within the implementation of OpenStax Chemistry.

Affordable Learning Georgia Grants Collections are intended to provide faculty with the frameworks to quickly implement or revise the same materials as a Textbook Transformation Grants team, along with the aims and lessons learned from project teams during the implementation process.

Documents are in .pdf format, with a separate .docx (Word) version available for download. Each collection contains the following materials:

• Linked Syllabus
• Initial Proposal
• Final Report

Structural And Functional Studies Of Nicotinamide Adenine Dinucleotide And Streptolysin S Biosynthesis Proteins From Streptococcus Pyogenes, William T. Booth

Theses and Dissertations

Invasive infections caused by Streptococcus pyogenes, also known as Group A Strep (GAS), results in approximately 600,000 deaths annually. With evidence of antibiotic-resistant strains of this bacterium on the rise, there is a need for the identification of new drug targets to control these infections. In our approach we target the quinolinate-salvage pathway (QSP) and the streptolysin S (SLS) biosynthesis pathway. The QSP provides a secondary pathway for NAD+ biosynthesis within this organism; the SLS pathway leads to the formation of a quorum sensing molecule (SLS). We hypothesize that inhibition of the pathways will lead to GAS cell death or …

Ligand-Induced Magnetic Changes In Metal Thin Films, Fiona Senta Oberbeck-Oxsher

Theses and Dissertations

The investigation of magnetic properties of thin films whose surfaces were modified by organic molecules shows that the addition of any functional group to the surface measurably changes the magnetic properties. The effect often scales with ligand strength and is not limited to surfaces with ferromagnetic properties. Improving upon the technique developed by Knaus et al. [1], a stable and sensitive device was developed to measure this magnetic effect using the planar Hall effect (PHE) in order to shed light onto controversial questions of purported paramagnetism of thiolated gold. There is a measureable non-diamagnetic response of thin gold layers when …

Iron Uptake And Accumulation Is A Target Of Nickel Toxicity During The Lag Phase In Escherichia Coli, Geoffrey Tuttle Ford

Theses and Dissertations

Various transition metals are essential to all forms of life, and are only required in trace amounts. But this dependence comes as a double-edged sword. All organisms must maintain a careful intracellular quota that does not traverse outside an acceptable range. One transition metal in particular is nickel. The importance of this transition metal has been debated widely and its function varies greatly between organisms, including bacteria. However, the adverse effects caused by over exposure to this metal have been the center of much experimentation in recent years. Still, the mechanisms of nickel toxicity and the subsequent effects on cellular …

The Development Of A High Resolution Deep-Uv Spatial Heterodyne Raman Spectrometer, Nirmal Lamsal

Theses and Dissertations

Raman spectroscopy is a light scattering technique that has a huge potential for standoff measurements in applications such as planetary exploration because a Raman spectrum provides a unique molecular fingerprint that can be used for unambiguous identification of target molecules. For this reason, NASA has selected a Raman spectrometer as one of the major instruments for its new Mars lander mission, Mars 2020, in the search for biomarkers that would be the indicators of past or present life. Raman scattering is strongest at UV wavelengths because of the inherent increase in the Raman cross section at shorter wavelengths and because …

Supplemental Materials For Building Data And Information Literacy In The Undergraduate Chemistry Curriculum, Yasmeen Shorish, Barbara A. Reisner

Yasmeen Shorish

Course syllabus from Chem 481, Fall 2015, to supplement the chapter "Building Data and Information Literacy in the Undergraduate Chemistry Curriculum" in the monograph Integrating Library and Information Literacy Into Chemistry Curricula - ACS Symposium Series, ACS Publications.

Development And Implementation Of Problem-Based Chemistry Experiments For Engineering Students In A Multi-Disciplinary Course, Tiffany Hesser, Stephanie R. Bunyea

Chemistry and Chemical Engineering Faculty Publications

This paper will describe the implementation and continuing development of five problem based laboratory experiments in a general chemistry course designed specifically for multiple disciplines of engineering students at the University of New Haven. The Problem Based Laboratory Experiments (PBLE) were developed to provide students with the opportunity to perform and develop experimental procedures working in interdisciplinary teams, while achieving a greater understanding of the role of chemistry in engineering fields. In each PBLE, students first complete a traditional chemistry experiment to gain an understanding of the chemical concepts and to become familiar with executing a written procedure with a …

Understanding College Students’ Exam Process In A General Chemistry Course, Angela Willson

Masters Theses

The main way most college chemistry courses assess what a student has learned is through a summative exam. After introductory science courses, such as general chemistry, many students cite poor teaching and disappointing grades in these courses as a reason for dropping out of STEM programs. There has been a lack of qualitative research on students’ experiences of the complete process of taking an exam from start to finish, or the exam process, which includes preparing for an exam, taking an exam, receiving feedback, and responding to feedback after the exam has been graded.

My goal in this exploratory study …

Development Of A [2]-Catenane Synthetic Method And A Student Beliefs Survey For A Hybrid Organometallics Course, Jourdan E. Lakes

Honors Theses

In this study, the value-added of a new upper-level chemistry course, CHEM 372-Organometallics, was defined using a Student Beliefs Survey that was answered by students in CHEM 372 and by faculty who teach upper-level chemistry courses at Coastal Carolina University. The laboratory portion of CHEM 372 focused on the synthesis of a [2]-catenane, which is a molecularly interlocked molecule (MIM). The intention was to give the CHEM 372 students a goal to work toward over the course of the semester instead of different, unrelated, experiments each week. Using this style of lab teaching, the students were introduced to graduate school-level …

2016-01-A3dsrinp-Csc-Sta-Cmb-522-Bps-542, Raymond Pulver, Neal Buxton, Xiaodong Wang, John Lucci, Jean Yves Hervé, Lenore Martin

Bioinformatics Software Design Projects

Cholesterol is carried and transported through bloodstream by lipoproteins. There are two types of lipoproteins: low density lipoprotein, or LDL, and high density lipoprotein, or HDL. LDL cholesterol is considered “bad” cholesterol because it can form plaque and hard deposit leading to arteries clog and make them less flexible. Heart attack or stroke will happen if the hard deposit blocks a narrowed artery. HDL cholesterol helps to remove LDL from the artery back to the liver.

Traditionally, particle counts of LDL and HDL plays an important role to understanding and prediction of heart disease risk. But recently research suggested that …

The Chemistry Of Photography, Nichole Marie Witten

Senior Theses

People nowadays are used to instant gratification when it comes to taking photographs. They look at a digital display, click a button, and get a perfectly focused and lighted picture that they can see right away. New technologies enable people to have pocket-sized digital cameras, their smart phones, with them at all times, and they’re easy convenient, and fast. Behind a single lens reflex (SLR) film camera, the scenario is much different. More time is needed in framing the image and adjusting the aperture and shutter speed to get the correct exposure, and the film must be processed darkroom before …

Conversion Of Cafo Manure Into A Slow-Release Fertilizer, Richard Allan Williams Iii

Honors Projects

Alginate polymer is known to form gel through the process of Ionotropic gelation. By use of extrusion and diffusion setting manure was encapsulated into gel beads. These beads were then tested to determine their potential for further testing as a manure treatment process. From the limited data in this preliminary study, it appears as though there is potential for further testing of alginate beads as a treatment process for manure. The treatment is potentially valuable because of the ease of filtration of the alginate beads, the low cost of transportation of the dehydrated beads, and because the limited data suggests …

Phosphonium/Phosphate Ionic Liquids As Lubricant Additives: The Synthesis And Testing Of Six Novel Ils, Matthew Scott Welmers

Graduate Theses - Chemistry and Biochemistry

In this study, ionic liquids (ILs) are defined as ionic materials with a melting temperature >100oC. ILs are characterized by their organic moieties which prevent crystallization, forcing the liquid phase. ILs are desirable as lubricant additives because of their ability to be fine-tuned by varying the identity of the cation/anion as well as the various organic functional moieties therein. Several novel phosphonium/phosphate ILs have been successfully synthesized via a simple, straightforward process. In this work a series of symmetric and asymmetric anionic phosphodiesters are developed and coordinated with two asymmetric alkyl phosphonium cations. These ILs are tested in SAE 10W30 …

E56h + E59h Mutation Affects Binding Of The Recombinant Haemphilus Influenza Carbonic Anhydrase To A Ni-Nta Column, Eric D. Lebel, Kathleen Cornely

Chemistry & Biochemistry Student Scholarship

The Haemophilus influenzae carbonic anhy- drase (HICA) is important in converting carbon dioxide to bicarbonate in bacteria. Endogenous cellular proteins, like Escherichia coli carbonic anhydrase (ECCA), have been observed to bind to a Ni-NTA column, which can be used as a means of protein purification. The possibility ex- ists that proteins that do not normally bind to Ni-NTA, like HICA, can be engineered using site directed mutagenesis to introduce histidine resi- dues that would give the protein the capability to bind, allowing for a one-step purification method. Site-directed mutagenesis was used to introduce the double mutation of E56H + E59H …