Physical Sciences and Mathematics Commons^™

Gender Differences In Lung Cancer Treatment And Survival, Margaret Anne Kowski

USF Tampa Graduate Theses and Dissertations

The objectives of this research were to test treatment and survival differences between women and men with lung cancer as there is minimal investigation in the literature. Three research questions were developed with statistical testing for gender differences based on similar cancer type, stage, treatment assignment and survival. Data for 44,863 primary lung cancer cases were collected from eight U.S. state-based cancer registries to investigate the research questions. The lung cancer incidence data included the morphological cell-types of adenocarcinoma (AC); squamous cell carcinoma (SCC); large cell carcinoma (LCC) and small cell carcinoma (SCC). Stage, grade, treatment type, as well as, …

Road-Based Landscape Metrics For Quantifying Habitat Fragmentation, Rebecca Whitehead Loraamm

USF Tampa Graduate Theses and Dissertations

Landscape metrics measure the composition and configuration of habitats within landscapes; often the goal is to measure fragmentation. While a variety of existing metrics characterize the connectivity and contiguity of habitat patches, most do not explicitly consider the fragmenting effects of roads in their formulations. This research develops a set of new landscape metrics that explicitly quantify how roads disconnect and break apart habitat patches. This research introduces the following four metrics to consider the fragmenting effects of transportation networks: (1) Number of Connected Patches, a measure of connectivity; (2) Euclidean Nearest Neighbor-Roads, a measure of proximity; (3) Road Density, …

The Impact Of Supply Chain And Network Structure On The Environmental Performance Of Sustainability-Focused Companies, Ozan Ozcan

USF Tampa Graduate Theses and Dissertations

The goal of this dissertation was to contribute to our understanding of the relationship between supply chain structure and the pursuit of a sustainability-driven corporate strategy. The literature indicates that in order to pursue a sustainability-focused strategy, an increased level of integration across the supply chain is required. However, there are also industry-level dynamics that impact observed levels of vertical integration. That is, some industries are naturally more integrated than others based on the maturity level of the industry. Thus, some firms may experience opposing forces regarding their sourcing strategies once they choose to pursue a sustainability-focused strategy.

To explore …

A Dynamic Hierarchical Web-Based Portal, Matthew James Spaulding

USF Tampa Graduate Theses and Dissertations

A dynamic hierarchical web-based portal was created to house a suite of web-based supply chain management applications. The portal was designed in a hierarchical manner to match the structure of large companies. Administrators of the the portal have the ability to form the portal in such a way to mimic the existing structure of their company. Access rights to the applications in the portal may be granted or denied per division and the users of the portal are placed in these divisions based on their duty in the company. In addition, users are granted roles which dictate their ability to …

Assessment Of Fertility Potential In Bottlenose Dolphins (Tursiops Truncatus): An Elisa-Based Biomarker Analysis, Leslie Schwierzke Wade

USF Tampa Graduate Theses and Dissertations

As apex predators in coastal systems, bottlenose dolphins (Tursiops truncatus) are susceptible to persistent organic pollutant (POP) accumulation and retention over time, which has prompted continued interest in understanding the extent to which contaminant body burdens or other stressors are sufficient to cause adverse sublethal effects on energetic fitness, immune function, or reproduction. Increasing our knowledge of reproductive endocrinology in bottlenose dolphins may provide insight into changes in reproductive rates, thereby expanding the capacity to assess conservation status. This study used the Enzyme-Linked ImmunoSorbent Assay (ELISA) technique to examine peptide fertility hormones [inhibin A, inhibin B and anti-Müllerian …

Informal Karst Education In The United States And Internationally, Leslie A. North

USF Tampa Graduate Theses and Dissertations

Despite the abundance of karst terrains and the important role they play in a wide variety of roles including supplying freshwater drinking supplies, no single, comprehensive study investigates the role of informal education for the improved understanding and protection of the terrains. Commonly overlooked anthropogenic karst disturbances partially occur because of the poor dissemination of scientific information to the general populace and policymakers and budgetary and time constraints of municipalities, thus generating a need to use informal education to fill these shortcomings. The purpose of this study was to: 1) establish the status of and quantify the amount of karst-related …

Synthesis And Characterization Of Self-Healing Poly (Carbonate Urethane) Carbon-Nanotube Composites, Roger Wesley Bass

USF Tampa Graduate Theses and Dissertations

Synthesis of high molar mass polycarbonate polyurethanes using a novel polyol is described. The resulting elastomers demonstrate excellent mechanical properties as well as the capability to re-heal after rupture without the addition of additives or imbedded healing agents. The self-healing functionality is shown to greatly improve with the addition of up to 1% single and multi-walled carbon nanotubes. The interface of the carbon nanotubes and self-healing polymer are probed using Raman techniques and provide an insight into how the self-healing actions are improved with the addition of carbon nanotubes.

Synthesis of polycarbonate polyurethanes and carbon nanotube composites using a novel …

Population Biology, Ecology, And Ecosystem Contributions Of The Eastern Oyster (Crassostrea Virginica) From Natural And Artificial Habitats In Tampa Bay, Florida, Michael Drexler

USF Tampa Graduate Theses and Dissertations

The objective of this project was to document the status of oysters, Crassostrea virginica, from non-reef habitats throughout Tampa Bay, Florida, and assess the ecosystem contributions of those populations relative to reef-dwelling oysters. The aspects of oyster ecology studied here include condition, prevalence and intensity of disease (Perkinsus marinus - dermo), reproductive activity (including stage, fecundity, and juvenile recruitment), adult oyster density, and the faunal community associated with the oysters.

The predominant source of variation was seasonal, with lesser contributions among sites, and in most cases, little or no effect of the habitat type. Oysters populations from each habitat …

A Study Of Complex Systems: From Magnetic To Biological, Douglas Carroll Lovelady

USF Tampa Graduate Theses and Dissertations

This work is a study of complex many-body systems with non-trivial interactions. Many such systems can be described with models that are much simpler than the real thing but which can still give good insight into the behavior of realistic systems. We take a look at two such systems. The first part looks at a model that elucidates the variety of magnetic phases observed in rare-earth heterostructures at low temperatures: the six-state clock model. We use an ANNNI-like model Hamiltonian that has a three dimensional parameter space and yields two-dimensional multiphase regions in this space. A low-temperature expansion of the …

Chemical Investigation Of The Antarctic Marine Invertebrates Austrodoris Kerguelenensis & Dendrilla Membranosa And The Antarctic Red Alga Gigartina Skottsbergii, John Alan Maschek

USF Tampa Graduate Theses and Dissertations

The marine realm and, in particular, the Antarctic benthos is largely unexplored and understudied. The chemical investigation reported herein reveals not only the biodiversity, but how that biodiversity manifests remarkable chemical diversity. In our continuing study of the nudibranch Austrodoris kerguelenensis, we have isolated a diverse suite of diterpenoid glyceride esters, palmadorins D - S (2.32 - 2.47), one of which is the first reported halogenated diterpene from a dorid nudibranch. Utilizing genomic data from collaborators, we have investigated the chemical diversity from phylogenetically unique specimens collected in close proximity to one another. Chemical groupings based on comparison of LC/MS …

Robotic Hand Evaluation Based On Task Specific Kinematic Requirements, Carlos Rafael Neninger

USF Tampa Graduate Theses and Dissertations

With the rise autonomous and robotic systems in field applications, the need for dexterous, highly adaptable end effectors has become a major research topic. Control mechanisms of robotics hands with a high number independent actuators is recognized as a complex, high dimensional problem, with exponentially complex algorithms. However, recent studies have shown that human hand motion possesses very high joint correlation which translates into a set of predefined postures, or synergies. The hand produces a motion using a complementing contribution of multiple joints, called synergies. The similarities place variables onto a common dimensional space, effectively reducing the number of independent …

Knowledge Guided Non-Uniform Rational B-Spline (Nurbs) For Supporting Design Intent In Computer Aided Design (Cad) Modeling, Khairan Rajab

USF Tampa Graduate Theses and Dissertations

For many years, incompatible computer-aided design (CAD) packages that are based on Non-uniform Rational B-Spline (NURBS) technology carried out the exchange of models and data through either neutral file formats (IGES or STEP) or proprietary formats that have been accepted as quasi industry standards. Although it is the only available solution at the current time, the exchange process most often produces unsatisfactory results. Models that are impeccable in the original modeling system usually end up with gaps or intersections between surfaces on another incompatible system. Issues such as loss of information, change of data accuracy, inconsistent tolerance, and misinterpretation of …

Potential Habitat Of Acropora Spp. On Florida Reefs, Katherine Wirt

USF Tampa Graduate Theses and Dissertations

Elkhorn and Staghorn corals (Acropora palmata, A. cervicornis) were listed as threatened species under the Endangered Species Act (ESA) in 2005. The threatened status of these species is unprecedented given the vital role they historically played as major constructors of western Atlantic and Caribbean coral reefs. The goal of my study was to evaluate the current extent of habitat of the two species using a database of reported in situ observations. From these observations, potential habitat maps were produced based on benthic substrata and depth parameters throughout the Florida reef tract using GIS software. Locations of 99% of …

The Influence Of Meteorological Parameters On Rainfall And Severe Weather In Pinellas County, Fl, Cristina A. Mazza

USF Tampa Graduate Theses and Dissertations

Pinellas County is located on a peninsula in Florida that experiences daily patterns of sea breeze associated rainfall mainly during the summer months of June through August. Previously, rainfall patterns, amounts and timing and severe weather in Pinellas County have not been examined considering dominant wind flow patterns, sea breeze circulations and other atmospheric variables. To improve forecasting of local mesoscale phenomena, this project examined the rainfall patterns, amounts and timing and severe weather occurrences that occur as a result of sea breezes and associated prevailing wind regimes within Pinellas County for the months of June, July and August for …

Crystal Engineering Of Pharmaceutical Cocrystals, Sreya Mukherjee

USF Tampa Graduate Theses and Dissertations

Pharmaceutical cocrystals use principles of crystal engineering for the design of crystalline forms of drugs and can improve their solubility, bioavailability, stability and other important properties without changing the efficacy of the drug. Herein reported are pharmaceutical cocrystals of two API's, caffeine and Pentoxifylline.

Research has indicated that caffeine has the ability to reverse AB; plaque deposition in the brain (believed to be the primary cause of Alzheimer's pathogenesis) and thus revert memory and improve cognitive impairment. But owing to the fast absorption rate and short half life, a controlled release formulation of caffeine would be clinically beneficial. Thus, novel …

First Year Sedimentological Characteristics And Morphological Evolution Of An Artificial Berm At Fort Myers Beach, Florida, Katherine Brutsche

USF Tampa Graduate Theses and Dissertations

Dredging is often conducted to maintain authorized depths in coastal navigation channels. Placement of dredged sediment in the form of nearshore berms is becoming an increasingly popular option for disposal. Compared to direct beach placement, nearshore berms have fewer environmental impacts such as shore birds and turtle nesting, and have more lenient sediment compatibility restrictions. Understanding the potential morphological and sedimentological evolution is crucial to the design of a nearshore berm. Furthermore, the artificial perturbation generated by the berm installation provides a unique opportunity to understand the equilibrium process of coastal morphodynamics.

Matanzas Pass and Bowditch Point, located on the …

Effects Of Solids Loadings And Particle Size Distribution On Siphon Ceramic Candle Filters, Danielle Renzi

USF Tampa Graduate Theses and Dissertations

In the rural areas of Madagascar only 29% of the population has access to clean water and 10% has access to improved sanitation. It has been estimated that environmental risk factors, such as inadequate access to clean drinking water and proper sanitation, are responsible for 94% of the diarrheal disease burden. This study was focused on testing a point-of-use technology called the Tulip filter, which is a siphon ceramic candle filter impregnated with silver. The purpose is to assess its feasibility for implementation in rural regions of Madagascar through a laboratory study performed at the University of South Florida.

The …

Modeling Endogenous Treatment Eects With Heterogeneity: A Bayesian Nonparametric Approach, Xuequn Hu

USF Tampa Graduate Theses and Dissertations

This dissertation explores the estimation of endogenous treatment effects in the presence of heterogeneous responses. A Bayesian Nonparametric approach is taken to model the heterogeneity in treatment effects. Specifically, I adopt the Dirichlet Process Mixture (DPM) model to capture the heterogeneity and show that DPM often outperforms Finite Mixture Model (FMM) in providing more flexible function forms and thus better model fit. Rather than fixing the number of components in a mixture model, DPM allows the data and prior knowledge to determine the number of components in the data, thus providing an automatic mechanism for model selection.

Two DPM models …

Evanescent Wave Coupling Using Different Subwavelength Gratings For A Mems Accelerometer, Al-Aakhir A. Rogers

USF Tampa Graduate Theses and Dissertations

A novel technique of coupling near-field evanescent waves by means of variable period subwavelength gratings (1.2 ìm and 1.0 ìm), using a 1.55 ìm infrared semiconductor laser is presented for the use of an optical MEMS accelerometer. The subwavelength gratings were fabricated on both glass and silicon substrates respectively.

Optical simulation of the subwavelength gratings was carried out to obtain the maximum coupling efficiency of the two subwavelength gratings; the grating thickness, grating width, and the grating separation were optimized. This was performed for both silicon and glass substrates.

The simulations were used to determine the total system noise, including …

Late Cretaceous Faunal Dynamics In The Western Interior Seaway: The Record From The Red Bird Section, Eastern Wyoming, Joshua Stephen Slattery

USF Tampa Graduate Theses and Dissertations

Studies examining bioevents (e.g., mass extinctions, faunal turnovers, diversification events) usually only scrutinize a short interval prior to such events, however, understanding their actual paleobiological implications requires a thorough understanding of the background conditions. The objective of this study is to document the background biodiversity dynamics in a single lithofacies of the Upper Cretaceous Pierre Shale that was deposited in an offshore setting of the Western Interior Seaway (WIS) and to place these changes into an environmental context. To assess the background biodiversity dynamics, the concretionary faunas of the Baculites eliasi through B. clinolobatus biozones of the Pierre Shale in …

Live Video Streaming From Android-Enabled Devices To Web Browsers, Justin M. Bailey

USF Tampa Graduate Theses and Dissertations

The wide-spread adoption of camera-embedded mobile devices along with the ubiquitous connection via WiFi or cellular networks enables people to visually report live events. Current solutions limit the configurability of such services by allowing video streaming only to fixed servers. In addition, the business models of the companies that provide such (free) services insert visual ads in the streamed videos, leading to unnecessary resource consumption.

This thesis proposes an architecture of a real-time video streaming service from an Android mobile device to a server of the user's choice. The real-time video can then be viewed from a web browser. The …

Initial Ablation Of The Laurentide Ice Sheet Based On Gulf Of Mexico Sediments, Elizabeth A. Brown

USF Tampa Graduate Theses and Dissertations

The objective of this project is to reconstruct a picture of initial Laurentide Ice Sheet retreat at the end of the Last Glacial Maximum (LGM) using geochemical proxies in Gulf of Mexico sediments, and place the reconstruction into global perspective. The project asks two questions. (1) Can a time frame be established for initial retreat of the Laurentide Ice Sheet? (2) If so, how does the timing compare to that of other large ice sheets and mountain glaciers in both hemispheres?

Sediment core MD02-2550 from the anoxic Orca Basin offers excellent preservation and a high sediment accumulation rate. Twelve accelerator …

An Analysis Of Remote Biometric Authentication With Windows, Brandy Marie Eyers

USF Tampa Graduate Theses and Dissertations

One thing that everyone seems to be worried about when it comes to his or her computer is security. If your computer is not secure then private information could be stolen. Many people now use passwords to protect themselves though they are discovering that using multi-factor authentication is much more secure. It allows you to use multiple different proofs of who you are. Biometrics is one of the ways to prove identity. Using it, you could log into a system with just a fingerprint, which is something that is very difficult to steal. We present a suite of software tools …

A Pilot Study Of Small-Scale Variations In Outdoor Benzene Concentrations, Samantha Catherine Fridh

USF Tampa Graduate Theses and Dissertations

Benzene is an important toxic chemical in urban air and known human carcinogen released substantially by mobile sources. It's important to understand the spatial variation of benzene concentrations in order to understand exposures of susceptible sub-populations such as children and minority groups. Current monitoring networks use large and expensive air samplers that require electricity and restrict the location and number of samplers, not allowing for fine spatial resolution data.

The goals of this study are to develop and evaluate protocols for passive sampling and analysis of ambient benzene concentrations, and conduct a pilot study investigating small-scale variations over an area …

Synthesis Of Small Molecule Inhibitors Of Janus Kinase 2, Phosphodiesterase Iv, Gabaa And Nmda Receptors: Investigation Of Mcmurry, Mannich And Chemoenzymatic Strategies, Meghanath Gali

USF Tampa Graduate Theses and Dissertations

Stilbenoids possess a wide range of biological properties such as, anticancer, antiplatelet aggregation, antiestrogenic, antibacterial, antifungal and antiatherogenic, etc. Owing to these therapeutic values, a great deal of attention attracted in the synthesis of derivatives of stilbenes. During the course of the study, G6 a novel stilbenoid was discovered, through high throughput screening, to be a potent inhibitor of mutated JAK2-V617F. The mutated JAK2 variant has been implicated in various myeloproliferative disorders (MPDs) including polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) has been targeted by therapeutics. Chapter 2 describes the synthesis of analogs of the stilbenoid G6 …

Relative Abundance And Spatial Distribution Of Lepomid Sunfishes In The Peace River, Justin Henry Heller

USF Tampa Graduate Theses and Dissertations

This study examines spatially continuous sampling data in order to investigate patterns of abundance and distribution of three recreationally important sunfish species (bluegill, redear, and spotted sunfish) along the main-stem of the Peace River, a large softwater river located in southwest Florida. A total of 467 electrofishing transects were sampled biannually from spring 2008 to spring 2010. Sampling sites ranged from the headwaters of the Peace River in Polk County, FL to the oligohaline waters located in Charlotte County, FL. All fish were collected with boat mounted electrofishing gear, and aquatic habitat and physiochemical water quality measurements were recorded at …

Physical Models Of Amyloid Fibril Assembly, Shannon Elizabeth Hill

USF Tampa Graduate Theses and Dissertations

Formation of large fibers and plaques by amyloid proteins is recognized as the molecular hallmark of an increasing number of human disorders, including Parkinson's disease, Alzheimer's disease and even type II diabetes. The broader objective of my research is to unravel the basic mechanisms that initiate and regulate fibril formation by amyloidogenic proteins. This objective is significant because even basic aspects of how fibril formation proceeds from a soluble, monomeric protein to an insoluble amyloid fibril remain much debated. Furthermore, there is increasingly strong evidence suggesting that intermediates of the aggregation process, with properties distinct from those of mature fibrils, …

From Source To Sink: An Isotopic Perspective On The Biogeochemical Relationship Between The Everglades And Florida Bay, Ana Maria Hoare

USF Tampa Graduate Theses and Dissertations

Increasing human populations and activities in coastal areas have led to high nutrient loading and estuarine ecosystem decline. Natural hydrological patterns in South Florida have been drastically altered by changes in water management and land use practices. As a result Florida Bay has experienced a series of negative ecosystem effects including hypersalinity events, degradation of water quality, and harmful algal blooms and declines in upper trophic level populations. To remediate ecosystem decline in Florida's coastal ecosystems, the Comprehensive Everglades Restoration Plan proposes to restore a more natural hydrologic flow in the Everglades. It is expected hydrologic restoration efforts will change …

Minimal And Symmetric Global Partition Polynomials For Reproducing Kernel Elements, Mario Jesus Juha

USF Tampa Graduate Theses and Dissertations

The Reproducing Kernel Element Method is a numerical technique that combines finite element and meshless methods to construct shape functions of arbitrary order and continuity, yet retains the Kronecker-δ property. Central to constructing these shape functions is the construction of global partition polynomials on an element. This dissertation shows that asymmetric interpolations may arise due to such things as changes in the local to global node numbering and that may adversely affect the interpolation capability of the method. This issue arises due to the use in previous formulations of incomplete polynomials that are subsequently non-affine invariant. This dissertation lays out …

Biodegradation Of Bisphenol-A And 17b-Estradiol In Soil Mesocosms Under Alternating Aerobic/Anoxic/Anaerobic Conditions, Won-Seok Kim

USF Tampa Graduate Theses and Dissertations

Soil-aquifer treatment (SAT) has been proposed as a method for reusing treated municipal wastewater. SAT is characterized by alternating cycles of aerobic and anaerobic conditions in the subsurface, in response to alternating cycles of flooding and drainage of a surface impoundment. It is not yet known how these alternating redox conditions affect the removal of potentially harmful endocrine-disrupting compounds (EDCs) from treated effluent.

The overall objective of my doctoral research is to determine the fate of EDCs in alternating aerobic/anoxic/anaerobic conditions under simulated SAT conditions. To assess the fate of EDCs in simulated SAT conditions, I first had to develop …