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Articles 91 - 120 of 1607
Full-Text Articles in Physical Sciences and Mathematics
Lithium And Lithium Isotope Behavior During High Temperature Solid/Fluid Exchanges: Examples From Iceland And The Izu-Bonin Forearc, Alex Maruszczak
Lithium And Lithium Isotope Behavior During High Temperature Solid/Fluid Exchanges: Examples From Iceland And The Izu-Bonin Forearc, Alex Maruszczak
USF Tampa Graduate Theses and Dissertations
The development of a method for lithium isotopic measurement was developed using a quadrupole, single-collector ICP-MS. Measured precision was ±1.00‰ 2σ over a 15-month period based on measurements of international rock standards. A 1-hour leach using cold, HCl was sufficient to remove alteration-related Li in minimally to moderately altered seafloor basalts. Measurements on the Holocene ages lavas from the neovolcanic zones of Iceland suggest no systematic Li isotopic variability among the differing Icelandic sources. Felsic samples from Hekla and Pumice contain elevated Li contents of >18ug/g while the tholeiitic and alkaline basalts are <8ug/g Li. Most of the island lies around MORB values of ~+3 to +5‰ with the exception of Western Volcanic Zone samples that show evidence for seawater inputs. The RN-17 drillcore, which penetrates >3000m through a hydrothermal system in the …8ug/g>
Conformational Dynamics And Free Energy Studies Of Dna And Other Biomolecules, Paul B. Orndorff
Conformational Dynamics And Free Energy Studies Of Dna And Other Biomolecules, Paul B. Orndorff
USF Tampa Graduate Theses and Dissertations
This work uses molecular dynamics simulations and enhanced sampling methods to investigate both the qualitative and quantitative properties of biomolecular systems. Conformational dynamics are critical in the study of biomolecular systems. Application of computer simulations to study dynamics of biomolecular systems allows for motions to be readily investigated at a resolution not possible in experimental techniques. In this work, the dynamics of uracil damaged and undamaged DNA is studied via molecular dynamics simulations. Uracil results in DNA from either misincorporation in the replication process or through spontaneous deamination of cytosine, and its presence in DNA can lead to mutations in …
Fuzzy Kc Clustering Imputation For Missing Not At Random Data, Markku A. Malmi Jr.
Fuzzy Kc Clustering Imputation For Missing Not At Random Data, Markku A. Malmi Jr.
USF Tampa Graduate Theses and Dissertations
Research has a variety of difficulties, especially when involving human subjects, and one of the most prevalent is the issue of missing data. Missing data will always be present in research due to the fact there is no perfect method for collecting data and protecting against human error or mechanical failure. This requires researchers to be able to mitigate the problems that come along with missing data; reduction in power of an analysis and bias introduced by the missing pattern. This research investigated a non-parametric method using a nested approach of fuzzy K-Modes and fuzzy C-Means clustering to impute missing …
An Analysis Of The Oil Pollution Act Of 1990: Regulatory Calibration In Anticipation Of 21st Century Environmental Disasters, Jessica S. Thornton
An Analysis Of The Oil Pollution Act Of 1990: Regulatory Calibration In Anticipation Of 21st Century Environmental Disasters, Jessica S. Thornton
USF Tampa Graduate Theses and Dissertations
After federal the Oil Pollution Act of 1990 (OPA 90) was promulgated in response to the Exxon Valdez oil spill in Alaska, it helped restructure the nation’s environmental response capabilities and modernize the commercial shipping industry to effectively decrease environmental shipping disasters. However, in the 33 years since OPA 90’s inception, the oil and gas industry has transformed, especially in the offshore realm, as industry adopts new drilling technologies to gain access to deeper and heretofore untapped maritime environments. Though there have been two catastrophic offshore drilling accidents since the turn of the 21st century, OPA 90 remains categorically unchanged, …
Apkcs Role In Neuroblastoma Cell Signaling Cascades And Implications Of Apkcs Inhibitors As Potential Therapeutics, Sloan Breedy
Apkcs Role In Neuroblastoma Cell Signaling Cascades And Implications Of Apkcs Inhibitors As Potential Therapeutics, Sloan Breedy
USF Tampa Graduate Theses and Dissertations
Neuroblastoma (NB) is a cancer that develops in the neuroblasts. It is the most common cancer in children under the age of 1 year, accounting for approximately 6% of all cancers. The prognosis of NB is linked to both age and degree of cell differentiation. This results in a range of survival rates for patients, with outcomes ranging from recurrence and mortality to high survival rates and tumor regression. Our previous work indicated that PKC-ι promotes cell proliferation in NB cells through the PKC-ι/Cdk7/Cdk2 cascade. We report on two atypical protein kinase inhibitors as potential therapeutic candidates against BE(2)-C and …
Land Use/Land Cover Uncertainty Analysis Using Hydrological Modeling In The Northern Watershed Of Lake Okeechobee, Andres Lora Santos
Land Use/Land Cover Uncertainty Analysis Using Hydrological Modeling In The Northern Watershed Of Lake Okeechobee, Andres Lora Santos
USF Tampa Graduate Theses and Dissertations
Over the past 150 years, Florida has undergone a major land-form transformation, transitioning from a natural to a primarily built environment. The state's population has grown exponentially, from less than 50,000 residents in the 1850s to approximately 22 million residents today. This population growth has led to significant changes in land use, including urbanization, mining, and agriculture. This trend is expected to continue, with projections indicating an increase in urbanization across the state. 2070 land use/land cover projections were used as input for the Watershed Assessment Model (WAM) to analyze the potential impact of these changes on flow, total nitrogen …
Time Series Analysis Of Pseudo-Nitzschia Species Composition, Domoic Acid, And Environmental Conditions In The Gulf Of Maine From 2013-2020, Christina Chadwick
Time Series Analysis Of Pseudo-Nitzschia Species Composition, Domoic Acid, And Environmental Conditions In The Gulf Of Maine From 2013-2020, Christina Chadwick
USF Tampa Graduate Theses and Dissertations
Phytoplankton are abundant in both fresh and marine waters and can form harmful algal blooms (HABs) by producing potent toxins that have devastating effects on human, wildlife, and economic health. The HAB-forming diatom genus, Pseudo-nitzschia, occurs globally and approximately half of the 59 currently identified species can produce the neurotoxin, domoic acid (DA). DA accumulates in shellfish and finfish and can cause Amnesic Shellfish Poisoning (ASP) in humans and DA Poisoning (DAP) in several species of wildlife, resulting in severe neurological dysfunction and mortality. Along with these health threats, DA toxicity is a major economic threat for shellfish and fish …
Ecohydrology, Cultural Perceptions, And Recovery Of Freshwater Wetlands In A Heavily Managed Urban Aquifer, Jessica Ashley Balerna
Ecohydrology, Cultural Perceptions, And Recovery Of Freshwater Wetlands In A Heavily Managed Urban Aquifer, Jessica Ashley Balerna
USF Tampa Graduate Theses and Dissertations
Freshwater wetlands provide essential ecosystem services that influence, and are influenced by, human perceptions and behaviors. I explore these feedbacks in the Tampa Bay region, which hosts numerous freshwater wetlands subjected to population increases, economic growth, and shifting management policies. These wetlands are embedded in urban and residential areas, where people can observe and respond to changes in wetland condition over time. I utilized long-term (1991–2018), high sample size (n=152) datasets to assess how wetland inundation responds to the interactive effects of climate variation and shifts in water conservation policies primarily related to cutbacks in groundwater extraction. As wetland ecosystem …
Remote Medical Diagnosis Via Infrared Thermography And Augmented Reality, Frederick M. Selkey
Remote Medical Diagnosis Via Infrared Thermography And Augmented Reality, Frederick M. Selkey
USF Tampa Graduate Theses and Dissertations
Fast, accurate, and non-invasive diagnostic techniques are required by the medical industry to increase the success of medical treatments and enhance the quality of patient care. Medical IRT has been demonstrated reasonably effective at diagnosing and monitoring several physiological conditions. Diversities in the human body, physical and psychological condition, measurement equipment, and environment all influence the sensitive readings obtained by passive IR measurement devices. New standards for medical IRT and fever screening have been demonstrated effective, but there is limited adherence to the guidelines [36]. Absolute temperature readings require regular calibration checks and can easily be thrown off by noise. …
The Role Of Eco-Tourism In The Environmental Protection Of The Mountains Of Pamirs, Furough Shakarmamadova
The Role Of Eco-Tourism In The Environmental Protection Of The Mountains Of Pamirs, Furough Shakarmamadova
USF Tampa Graduate Theses and Dissertations
ABSTRACTThe Central Asian nation of Tajikistan became independent in 1991. Tajikistan is a mountainous country with a great potential for tourism development. Nevertheless, there are limitations to the development of eco-tourism. I conducted my study to investigate the potential for developing eco-tourism in the eastern part of Tajikistan (the Pamirs). My overarching question was how does eco-tourism relate to the protection of the environment in Pamirs and can it improve the quality of people's lives? To answer this question, I focused on identifying the Best Management Practices (BMP) of eco-tourism in the region and what specific policies, if any, exist …
Diazirines And Oxaziridines As Nitrogen Transfer Reagents In Drug Discovery, Khalilia C. Tillett
Diazirines And Oxaziridines As Nitrogen Transfer Reagents In Drug Discovery, Khalilia C. Tillett
USF Tampa Graduate Theses and Dissertations
Synthetic organic chemistry has long served as a driver of innovation in the drug discovery and development process. Given the prevalence of the nitrogen atom in small molecule drugs, improved methods for C–N bond installation are in high demand. Heteroatom transfer reagents such as oxaziridines and diazirines can be used to selectively deliver nitrogen atom(s) to organic compounds. Herein, I’ll describe my work utilizing Armstrong’s oxaziridine (TBDOT) in peptide backbone modification, and diazirines (TPD) in the development of a hydroamination reaction.
Peptide backbone N-amination has emerged as an attractive peptidomimetic strategy in the design of amyloid aggregation inhibitors. In addition …
Deep Reinforcement Learning Based Optimization Techniques For Energy And Socioeconomic Systems, Salman Sadiq Shuvo
Deep Reinforcement Learning Based Optimization Techniques For Energy And Socioeconomic Systems, Salman Sadiq Shuvo
USF Tampa Graduate Theses and Dissertations
Optimization, which refers to making the best or most out of a system, is critical for an organization's strategic planning. Optimization theories and techniques aim to find the optimal solution that maximizes/minimizes the values of an objective function within a set of constraints. Deep Reinforcement Learning (DRL) is a popular Machine Learning technique for optimization and resource allocation tasks. Unlike the supervised ML that trains on labeled data, DRL techniques require a simulated environment to capture the stochasticity of real-world complex systems. This uncertainty in future transitions makes the planning authorities doubt real-world implementation success. Furthermore, the DRL methods have …
Graph Analysis On Social Networks, Shen Lu
Graph Analysis On Social Networks, Shen Lu
USF Tampa Graduate Theses and Dissertations
With the development of transportation network, social network, and communication network, there are many applications in streaming data. For example, traffic congestion happens between the origin and destination of daily trips. Traffic analysis can help plan the trips so that traffic congestion can be avoided. Social network and communication network represent the behaviors of the entire population. People build connections based on their hobbies, daily activities, photos, videos, simple messages, and even anonymous web surfing. All of these can be turned into commercial use, such as product marketing, business network building, and technology trending. Data science is about how to …
Self-Assembly Of Metallo-Supramolecules Based On Terpyridine And Its Derivatives, Yu Yan
Self-Assembly Of Metallo-Supramolecules Based On Terpyridine And Its Derivatives, Yu Yan
USF Tampa Graduate Theses and Dissertations
By studying coordination complexes in nature, such as chlorophyll, heme, and Enterobacter, we have learned that the structures of coordination complexes are closely related to their functions. However, it remains a challenge to achieve elaborate structures and sophisticated functions of complexes through synthetic methods. In the supramolecular chemistry field, coordination-driven self-assembly as a bottom-up approach are used to construct diverse supramolecules with well-defined structures and desired functions. The ways to achieve the goal including (1) rearranging components through coordination; (2)linking metal ions and organic frameworks to complete energy transfer; (3) converting between assembly and disassembly due to detection of stimuli. …
Reducing Instrumentation Barriers Of Diffuse Correlation Spectroscopy For Low-Cost Deep Tissue Blood Flow Monitoring, Arindam Biswas
Reducing Instrumentation Barriers Of Diffuse Correlation Spectroscopy For Low-Cost Deep Tissue Blood Flow Monitoring, Arindam Biswas
USF Tampa Graduate Theses and Dissertations
Cerebral blood flow (CBF) is a good indicator of brain health as blood carries necessary nutrients, oxygen, and metabolic byproducts. Quantitative blood flow information can be used in several clinical and therapeutic applications such as stroke detection, measuring autoregulation, evaluating brain injury, or determining neuronal activity. Over the past few decades, light-based deep tissue hemodynamic detection modalities have become popular for non-invasive CBF measurements. In particular, noninvasive Diffuse Correlation Spectroscopy (DCS), has become a tool of choice for research and clinical applications due to its depth sensitivity (>1 cm), portability, validity against other technologies such as Magnetic Resonance Imaging …
Frequency Domain Diffuse Optics Spectroscopies For Quantitative Measurement Of Tissue Optical Properties, Sadhu Moka
Frequency Domain Diffuse Optics Spectroscopies For Quantitative Measurement Of Tissue Optical Properties, Sadhu Moka
USF Tampa Graduate Theses and Dissertations
Tissue oxygen saturation, blood flow and blood volume are physiological bio-markers of tissue health. Diffuse Optical Spectroscopy(DOS) and Diffuse Correlation Spectroscopy (DCS) are two complementary approaches to measure tissue oxygen saturation and blood flow respectively. Quantitative Diffuse Optical Spectroscopy (DOS) uses multi-spectral intensities of near-infrared light that have been modulated at RF frequencies to estimate static tissue optical properties and hence concentrations of oxygenated and de-oxygenated hemoglobin. Diffuse Correlation Spectroscopy estimates tissue dynamics - i.e., blood flow, by measuring temporal intensity auto-correlation function of backscattered light diffusing through the tissue. Conventionally, DCS instruments use coherent light sources with constant intensity. …
A Multiple Input Multiple Output Framework For The Automatic Optical Fractionator-Based Cell Counting In Z-Stacks Using Deep Learning, Palak Dave
USF Tampa Graduate Theses and Dissertations
Quantifying cells in a defined region of biological tissue is critical for many clinical and preclinical studies, especially in pathology, toxicology, cancer, and behavior. Unbiased stereology is the state-of-art method for quantification of the total number and other morphometric parameters of stained objects in a defined region of biological tissue. As part of a program to develop accurate, precise, and more efficient automatic approaches for quantifying morphometric changes in biological tissue, our group has shown that both deep learning-based and hand-crafted algorithms can estimate the total number of histologically stained cells at their maximal profile of focus in extended depth …
Data-Driven State Estimation For Improved Wide Area Situational Awareness In Smart Grids, Md Jakir Hossain
Data-Driven State Estimation For Improved Wide Area Situational Awareness In Smart Grids, Md Jakir Hossain
USF Tampa Graduate Theses and Dissertations
Wide area situational awareness (WASA) in smart grids includes automatic monitoring, perception and detection of anomalies in these systems. The goal of WASA is to make smart grids aware of their physical and operational state for more effective operational decisions and control. As such, tracking the system's state or state estimation is one of the key objectives of WASA. The extensive integration of cyber elements into smart grids, such as large deployment of various monitoring and measurement devices, provides new opportunities to improve WASA. However, the tight coupling of power grids with cyber components introduces vulnerabilities to cyber and physical …
Quantifying A 21-Year Surface Water And Groundwater Interaction In A Ridge And Valley Lake Environment Using A Highly Constrained Modeling Approach, Richard T. Bowers Jr.
Quantifying A 21-Year Surface Water And Groundwater Interaction In A Ridge And Valley Lake Environment Using A Highly Constrained Modeling Approach, Richard T. Bowers Jr.
USF Tampa Graduate Theses and Dissertations
Karst lakes are ubiquitous in ridge terrain settings in limestone aquifer coastal plain environments. In west-central Florida, these lakes are frequently connected to the Upper Floridan aquifer and have unique aquifer recharge characteristics. They have been selectively studied because they commonly have no or very limited surface water discharge and limited drainage areas, have appreciable surface water and groundwater interaction and leak to the deep aquifer. An innovative modeling approach was developed to collectively understand and more precisely quantify this vertical leakage, both from a lake-specific and regional water budget standpoint, for a 21-year study period (2000-2020). A unique, calibrated …
Optimizing Lake Okeechobee Watershed Management And Reservoir Operations For Water Quality Improvement, Osama Mahrous Mossad Tarabih
Optimizing Lake Okeechobee Watershed Management And Reservoir Operations For Water Quality Improvement, Osama Mahrous Mossad Tarabih
USF Tampa Graduate Theses and Dissertations
Rivers around the globe have been altered as people have constructed water resources infrastructure to store water for different human needs, causing negative impacts on ecosystem processes and functions. Environmental flows have been introduced to restore deteriorated riverine ecosystems; however, environmental flows have not always been practical or adequate to restore environment conditions in rivers globally. Lake Okeechobee is a large subtropical lake that plays a pivotal role in South Florida water system providing various water demands for the surrounding communities as well as providing crucial services to the ecosystem of South Florida. However, hydrologic alterations and nutrient (phosphorus and …
Volcano And Tectonic Hazard Modeling Using Interdisciplinary Geophysical And Geodetic Methods, Mitchell Scott Hastings
Volcano And Tectonic Hazard Modeling Using Interdisciplinary Geophysical And Geodetic Methods, Mitchell Scott Hastings
USF Tampa Graduate Theses and Dissertations
Volcanic and tectonic hazards such as volcanic eruptions, earthquakes and tsunamis present risks to about ~45% of the global population. They have caused at least 1.5 trillion dollars in damages worldwide since the start of the 20th century, and the costs are accelerating as population increases. In this dissertation, new data are combined with existing information and novel modeling approaches to quantify volcanic, earthquake and tsunami hazards.
The Blackfoot Reservoir Volcanic Field (BRVF) is a bimodal volcanic field on southeastern margin of the Eastern Snake River Plain in Idaho. In the BRVF, gravity anomalies reveal two shallow silicic intrusions that …
Using Gis-Based Land Use Strategies To Minimize The Impacts Of Urbanization On Agricultural Land And Forest Cover: Case Study Of The City Of Limbe, Cameroon, Lucy Ebude Deba Enomah
Using Gis-Based Land Use Strategies To Minimize The Impacts Of Urbanization On Agricultural Land And Forest Cover: Case Study Of The City Of Limbe, Cameroon, Lucy Ebude Deba Enomah
USF Tampa Graduate Theses and Dissertations
Urbanization is one of the most dominant phenomena of the 21st century; it is propelled by natural growth and rural-to-urban migration. This latter is typically a product of rural residents moving to urban centres in search of economic opportunities. This phenomenon is accompanied by immense land use and cover changes – predominantly agricultural and forest lands to urban land uses such as buildings and infrastructure. The goal of this research was to contribute to efforts to minimize the impacts of urbanization on agricultural land and forest cover in Limbe, Cameroon, and to develop GIS-based strategies to allocate suitable land for …
Development Of Lipidated Antimicrobial Polycarbonates, Ruixuan Gao
Development Of Lipidated Antimicrobial Polycarbonates, Ruixuan Gao
USF Tampa Graduate Theses and Dissertations
Antimicrobial resistance is a global challenge owing to the lack of discovering effective antibiotic agents. Antimicrobial polymers containing the cationic groups and hydrophobic groups which mimic natural host-defense peptides (HDPs) show great promise in combating bacteria. Herein, we report the synthesis of lipidated polycarbonates bearing primary amino groups and hydrophobic moieties (including both the terminal lipid alkyl chain and hydrophobic groups in the sequences) by ring-opening polymerization. The hydrophobic/hydrophilic group ratios were adjusted deliberately and the lengths of the lipid tails at the end of the polymers were modified to achieve the optimized combination for the lead polymers, which exhibited …
Surviving A Broken System: Synergies Between Solidarity Economies And Sustainable Development Goals, Julie Beach
Surviving A Broken System: Synergies Between Solidarity Economies And Sustainable Development Goals, Julie Beach
USF Tampa Graduate Theses and Dissertations
Capitalism has created problems including wealth polarization, rapid depletion of natural resources, and pervasive systemic societal issues. Hard work is not enough to solve the unequal distribution and barriers preventing access to necessities. Sustainable Development Goals (SDGs) were created to remedy the harsh reality of global inequities and negative environmental impacts by working towards a more just and equitable future for all. Solidarity Economies (SE) offer an alternative framework to achieve these goals.
This research used multiple qualitative methods to investigate the synergies between SE and SDGs in a growing urban environment. St. Petersburg, FL struggles with affordable housing, food …
Designing A Messaging Strategy To Improve Information Security Policy Compliance, Federico Giovannetti
Designing A Messaging Strategy To Improve Information Security Policy Compliance, Federico Giovannetti
USF Tampa Graduate Theses and Dissertations
Lack of employee compliance with information security policies is a key factor driving security incidents. Information security practitioners struggle to enforce policy compliance while employees try to curtail safeguards in favor of expediency and other perceived business goals. Several studies have shown individual and organizational factors influencing this type of employee behavior. However, few have recommended management-level interventions that can be used as a solution framework by information security practitioners.
This research utilized the Design Science Research (DSR) methodology to develop a management-level intervention based on a messaging strategy that aims to help information security practitioners improve the information security …
Farmer Adoption Of Advanced Technology In Agribusiness, Justin W. Belcher
Farmer Adoption Of Advanced Technology In Agribusiness, Justin W. Belcher
USF Tampa Graduate Theses and Dissertations
Normally, family-owned farms are slow to adopt advanced technologies though these technologies can provide several benefits to the farm and have the potential to increase farm production volumes to help meet future population growth. The goal of this study was to document the factors that influence the adoption decision of advanced technologies by family-owned farms and what strategies can be used to motivate adoption. Case study research was conducted to gather data in a more structured way from family-owned farms typically excluded from past research for the purpose of comparing similarities across similar and dissimilar farms. For generalizing similarities, a …
Development Of An Automated Platform For Sensing And Differentiating Vapor-Phase Btex Constituents, Jonathan Samuelson
Development Of An Automated Platform For Sensing And Differentiating Vapor-Phase Btex Constituents, Jonathan Samuelson
USF Tampa Graduate Theses and Dissertations
Light aromatic hydrocarbons are an inevitable byproduct of fossil fuel extraction, refinement, distribution, and use. The four lightest and most prevalent of these are benzene, toluene, ethylbenzene, and xylene, which are known collectively as BTEX. In spite of their chemical similarity these species have markedly different effects on human health and substantially different concentrations are permitted by OSHA in workplaces and by the EPA in ambient air and groundwater. Real-time detection, identification, and quantification of these species is therefore of great importance wherever they see industrial use.This work represents the continuation and advancement of a line of research in which …
Statistical Methods For Reliability Test Planning And Data Analysis, Oluwaseun Elizabeth Otunuga
Statistical Methods For Reliability Test Planning And Data Analysis, Oluwaseun Elizabeth Otunuga
USF Tampa Graduate Theses and Dissertations
This dissertation develops several statistical methods to advance the techniques and applications in the fields of reliability test planning and data analysis as well as statistical modeling and analysis in survival analysis.
The first project focuses on developing new demonstration test plans for lifetime data based on considering multiple objectives. Reliability demonstration tests have been broadly used for assuring reliability performance at the desired confidence level. We consider lifetime data that follows a Weibull distribution which has been broadly used for modeling a variety of shapes of lifetime distributions. When planning a demonstration test, there are often multiple aspects to …
Task Progress Assessment And Monitoring Using Self-Supervised Learning, Sainath Reddy Bobbala
Task Progress Assessment And Monitoring Using Self-Supervised Learning, Sainath Reddy Bobbala
USF Tampa Graduate Theses and Dissertations
Robotic manipulation for cooking requires a thorough understanding of the cooking environment. The robot must understand the cooking objects and their states at each intermediate level as the process continues. To understand these states, we need frame-level annotations. To overcome this frame-level dependency, we introduce a self-supervised learning method to obtain the frame-level state representation with ”temporal video alignment” and ”contrastive learning.”In this work, we use self-supervised learning to train a model using multiple videos of the same action being performed in various settings. This model can extract frame-level embedding space and align videos via simple distance-based matching. We show …
Generative Spatio-Temporal And Multimodal Analysis Of Neonatal Pain, Md Sirajus Salekin
Generative Spatio-Temporal And Multimodal Analysis Of Neonatal Pain, Md Sirajus Salekin
USF Tampa Graduate Theses and Dissertations
Neonates can not express their pain like an adult person. Due to the lacking of proper muscle growth and inability to express non-verbally, it is difficult to understand their emotional status. In addition, if the neonates are under any treatment or left monitored after any major surgeries (post-operative), it is more difficult to understand their pain due to the side effect of medications and the caring system (i.e. intubated, masked face, covered body with blanket, etc.). In a clinical environment, usually, bedside nurses routinely observe the neonate and measure the pain status following any standard clinical pain scale. But current …