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2007

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Articles 1861 - 1890 of 6758

Full-Text Articles in Physical Sciences and Mathematics

Power Spectra Of The Total Occupancy In The Totally Asymmetric Simple Exclusion Process, D. `A. Adams, R. K. P. Zia, Beate Schmittmann Jul 2007

Power Spectra Of The Total Occupancy In The Totally Asymmetric Simple Exclusion Process, D. `A. Adams, R. K. P. Zia, Beate Schmittmann

Beate Schmittmann

As a solvable and broadly applicable model system, the totally asymmetric exclusion process enjoys iconic status in the theory of nonequilibrium phase transitions. Here, we focus on the time dependence of the total number of particles on a 1-dimensional open lattice and its power spectrum. Using both Monte Carlo simulations and analytic methods, we explore its behavior in different characteristic regimes. In the maximal current phase and on the coexistence line (between high and low density phases), the power spectrum displays algebraic decay, with exponents −1.62 and −2.00, respectively. Deep within the high and low density phases, we find pronounced …


Absolute And Relative Surrogate Measurements Of The 236U(N,F) Cross Section As A Probe Of Angular Momentum Effects, B. F. Lyles, L. A. Bernstein, J. T. Burke, F. S. Dietrich, J. Escher, I. Thompson, D. L. Bleuel, R. M. Clark, P. Fallon, J. Gibelin, A. O. Macchiavelli, M. A. Mcmahan, L. Phair, E. Rodriguez-Vieitez, M. Wiedeking, C. W. Beausang, S. R. Lesher, B. Darakchieva, M. Evtimova Jul 2007

Absolute And Relative Surrogate Measurements Of The 236U(N,F) Cross Section As A Probe Of Angular Momentum Effects, B. F. Lyles, L. A. Bernstein, J. T. Burke, F. S. Dietrich, J. Escher, I. Thompson, D. L. Bleuel, R. M. Clark, P. Fallon, J. Gibelin, A. O. Macchiavelli, M. A. Mcmahan, L. Phair, E. Rodriguez-Vieitez, M. Wiedeking, C. W. Beausang, S. R. Lesher, B. Darakchieva, M. Evtimova

Physics Faculty Publications

Using both the absolute and relative surrogate techniques, the 236U(n,f) cross section was deduced over an equivalent neutron energy range of 0 to 20 MeV. A 42 MeV 3He beam from the 88 Inch Cyclotron at Lawrence Berkeley National Laboratory was used to perform a (3He,α) pickup reaction on targets of 235U (Jπ=7/2) and 238U (Jπ = 0+) and the fission decay probabilities were determined. The 235U(3He,αf) and 238U(3He,αf) were surrogates for 233 …


Additive-Assisted, Cerium-Based, Corrosion-Resistant E-Coating, James O. Stoffer, Thomas J. O'Keefe, Eric L. Morris, Xuan Lin, Scott A. Hayes, Pu Yu Jul 2007

Additive-Assisted, Cerium-Based, Corrosion-Resistant E-Coating, James O. Stoffer, Thomas J. O'Keefe, Eric L. Morris, Xuan Lin, Scott A. Hayes, Pu Yu

Chemistry Faculty Research & Creative Works

Corrosion resistance of metallic components such as stainless steel components of vehicles, and especially aluminum- based components of aircraft, is enhanced by application of an e-coat paint or primer which is enhanced by incorporation of cerium ions into the e-coat electrolytic bath. The resulting overall coating includes a cerium-based layer under a cerium-enhanced e-coat paint or primer layer.


The Smallest Base And Precious Metal Deposits In The World: Vapor Transport And Deposition Of Co-Cu-Sn-Ag Alloys In Vesicles, Elizabeth Adele Outdoor Hunter Jul 2007

The Smallest Base And Precious Metal Deposits In The World: Vapor Transport And Deposition Of Co-Cu-Sn-Ag Alloys In Vesicles, Elizabeth Adele Outdoor Hunter

Theses and Dissertations

Metallic bronze-Co-Ag alloys ranging from1-90 µm have been discovered in bomb and lava vesicles from the mafic volcanoes of Kilauea in Hawaii and Vesuvius, Stromboli and Etna in Italy. It is inferred that the metals for these alloys were transported (in part) as chloride complexes, and that the metal ratios in the alloys may be a function of S/Cl. Alloy compositions in each system are extremely heterogeneous with Co concentrations from 1% to 94%, Cu from 2% to 89%, Sn from 1% to 22% and Ag from 0.5% to 42%. Maximum abundances (in wt%) of other trace or minor elements …


The Mid-Infrared Emission Of M87, Eric S. Perlman, Rachel E. Mason, Christopher C. Packham, Nancy A. Levenson, Moshe Elitzur, Justin J. Schaefer, Masatoshi Imanishi, William B. Sparks, James T. Radomski Jul 2007

The Mid-Infrared Emission Of M87, Eric S. Perlman, Rachel E. Mason, Christopher C. Packham, Nancy A. Levenson, Moshe Elitzur, Justin J. Schaefer, Masatoshi Imanishi, William B. Sparks, James T. Radomski

Aerospace, Physics, and Space Science Faculty Publications

We discuss Subaru and Spitzer Space Telescope imaging and spectroscopy of M87 in the mid-infrared (mid-IR) from 5 to 35 μm. These observations allow us to investigate mid-IR emission mechanisms in the core of M87 and to establish that the flaring, variable jet component HST-1 is not a major contributor to the mid-IR flux. The Spitzer data include a high signal-to-noise ratio 15-35 μm spectrum of the knot A/B complex in the jet, which is consistent with synchrotron emission. However, a synchrotron model cannot account for the observed nuclear spectrum, even when contributions from the jet, necessary due to the …


Measurement Of The Shape Of The Boson Rapidity Distribution For Pp̅ → Z/ Γ* → ℯ+- + X Events Produced At √S Of 1.96 Tev, V. M. Abazov, Kenneth A. Bloom, Gregory R. Snow, D0 Collaboration Jul 2007

Measurement Of The Shape Of The Boson Rapidity Distribution For Pp̅ → Z/ Γ* → ℯ+ℯ- + X Events Produced At √S Of 1.96 Tev, V. M. Abazov, Kenneth A. Bloom, Gregory R. Snow, D0 Collaboration

Kenneth Bloom Publications

We present a measurement of the shape of the boson rapidity distribution forpp̅ → Z/ γ * → ℯ+- + X events at a center-of-mass energy of 1.96 TeV. The measurement is made for events with electron-positron mass 71<M ℯℯ < 111 GeV and uses 0.4 fb-1 of data collected at the Fermilab Tevatron collider with the D0 detector. This measurement significantly reduces the uncertainties on the rapidity distribution in the forward region compared with previous measurements. Predictions of next-to-next-to-leading order (NNLO) QCD are found to agree well with the data over the full rapidity range.


A Comparative Simulation Study Of Robust Estimators Of Standard Errors, Natalie Johnson Jul 2007

A Comparative Simulation Study Of Robust Estimators Of Standard Errors, Natalie Johnson

Theses and Dissertations

The estimation of standard errors is essential to statistical inference. Statistical variability is inherent within data, but is usually of secondary interest; still, some options exist to deal with this variability. One approach is to carefully model the covariance structure. Another approach is robust estimation. In this approach, the covariance structure is estimated from the data. White (1980) introduced a biased, but consistent, robust estimator. Long et al. (2000) added an adjustment factor to White's estimator to remove the bias of the original estimator. Through the use of simulations, this project compares restricted maximum likelihood (REML) with four robust estimation …


Synthesis And Antiviral Evaluation Of Some 3'-Carboxymethyl-3'-Deoxyadenosine Derivatives, Houguang Shi Jul 2007

Synthesis And Antiviral Evaluation Of Some 3'-Carboxymethyl-3'-Deoxyadenosine Derivatives, Houguang Shi

Theses and Dissertations

3'-Carboxymethyl-3'-deoxyadenosine derivatives were prepared from 2'-O-TBDMS-3'-deoxy-3'-[(ethoxycarbonyl)methyl]adenosine (1) via simple and efficient procedures. Conversion of 1 to 5'-azido-2'-O-TBDMS-3', 5'-dideoxy -3'-[(ethoxycarbonyl) methyl] adenosine (4) was accomplished via a novel one-pot method employing 5'-activation (TosCl) followed by efficient nucleophilic displacement with tetramethylguanidinium azide. Compound 4 was converted to a 5'-[(N-methylcarbamoyl)amino] derivative (5) via one-pot reduction/acylation employing H2/Pd-C followed by treatment with p-nitrophenyl N-methylcarbamate. The latter step of this two-step process required an efficient source of p-nitrophenyl N-methylcarbamate, thus a highly efficient new method for preparing p-nitrophenyl N-alkylcarbamate was developed. N6-phenylcarbamoyl groups were introduced by treatment with phenylisocyanate, and an efficient new method for …


Minimizing Product Shrinkage Across The Supply Chain Using Radio Frequency Identification: A Case Study On A Major Australian Retailer, N. Huber, Katina Michael Jul 2007

Minimizing Product Shrinkage Across The Supply Chain Using Radio Frequency Identification: A Case Study On A Major Australian Retailer, N. Huber, Katina Michael

Faculty of Informatics - Papers (Archive)

This paper identifies the contributing factors of product shrinkage and investigates the current state of anti-theft technology as part of the loss prevention strategy for a major Australian retailer. Using a case study approach a total of eleven interviews were conducted with employees of the retailer to identify factors contributing to product shrinkage and ways to overcome these through the use of radio frequency identification (RFID) technology. Known sources of product shrinkage included: warehouse discrepancies, internal and external theft, product recalls, shop return fraud, extortion, human and system error, poor stock control, poor rotation of stock, misplaced product items, lost …


Verifying Semantic Business Process Models In Inter-Operation, George Koliadis, Aditya Ghose Jul 2007

Verifying Semantic Business Process Models In Inter-Operation, George Koliadis, Aditya Ghose

Faculty of Informatics - Papers (Archive)

Process inter-operation is characterized as cooperative interactions among loosely coupled autonomous constituents to adaptively fulfill system-wide purpose. Issues of inconsistency can be anticipated in inter-operating processes given their independent management and design. To reduce inconsistency (that may contribute to failures) effective methods for statically verifying behavioral interoperability are required. This paper contributes a method for practical, semantic verification of interoperating processes (as represented with BPMN models). We provide methods to evaluate consistency during process design where annotation of the immediate effect of tasks and sub-processes has been provided. Furthermore, some guidelines are defined against common models of inter-operation for scoping …


Beyond Mere Compliance Of Rfid Regulations By The Farming Community: A Case Study Of The Cochrane Dairy Farm, A. Trevarthen, Katina Michael Jul 2007

Beyond Mere Compliance Of Rfid Regulations By The Farming Community: A Case Study Of The Cochrane Dairy Farm, A. Trevarthen, Katina Michael

Faculty of Informatics - Papers (Archive)

Radio-frequency identification (RFID) is changing the face of livestock identification and management. Beyond satisfying the regulations of government agencies for livestock to be a part of a national identification system for tracking purposes, farmers are now considering venturing beyond mere basic compliance systems. Once installed, farmers have begun to realize that their initial capital investment into an RFID system holds great strategic potential. The initial outlay while substantial is a once only cost that with a few more application-centric uses can yield a return on investment manifold. This paper presents a case study of the Cochrane Dairy Farm situated on …


First Cross-Correlation Analysis Of Interferometric And Resonant-Bar Gravitational-Wave Data For Stochastic Backgrounds, B. Abbott, R. Abbott, R. Adhikari, J. Agresti, P. Ajith, B. Allen, R. Amin, S. B. Anderson, W. G. Anderson, M. Arain, M. Araya, H. Armandula, M. Ashley, S. Aston, P. Aufmuth, C. Aulbert, S. Babak, S. Ballmer, H. Bantilan, B. C. Barish, C. Barker, D. Barker, B. Barr, P. Barriga, M. A. Barton, K. Bayer, K. Belczynski, J. Betzwieser, P. T. Beyersdorf, B. Bhawal, I. A. Bilenko, Tiffany Z. Summerscales Jul 2007

First Cross-Correlation Analysis Of Interferometric And Resonant-Bar Gravitational-Wave Data For Stochastic Backgrounds, B. Abbott, R. Abbott, R. Adhikari, J. Agresti, P. Ajith, B. Allen, R. Amin, S. B. Anderson, W. G. Anderson, M. Arain, M. Araya, H. Armandula, M. Ashley, S. Aston, P. Aufmuth, C. Aulbert, S. Babak, S. Ballmer, H. Bantilan, B. C. Barish, C. Barker, D. Barker, B. Barr, P. Barriga, M. A. Barton, K. Bayer, K. Belczynski, J. Betzwieser, P. T. Beyersdorf, B. Bhawal, I. A. Bilenko, Tiffany Z. Summerscales

Faculty Publications

Data from the LIGO Livingston interferometer and the ALLEGRO resonant-bar detector, taken during LIGO's fourth science run, were examined for cross correlations indicative of a stochastic gravitational-wave background in the frequency range 850-950 Hz, with most of the sensitivity arising between 905 and 925 Hz. ALLEGRO was operated in three different orientations during the experiment to modulate the relative sign of gravitational-wave and environmental correlations. No statistically significant correlations were seen in any of the orientations, and the results were used to set a Bayesian 90% confidence level upper limit of Ωgw(f)≤1.02, which corresponds to a gravitational-wave strain at 915 …


Extreme Ultraviolet Polarimetry With Laser-Generated High-Order Harmonics, Nicole Brimhall Jul 2007

Extreme Ultraviolet Polarimetry With Laser-Generated High-Order Harmonics, Nicole Brimhall

Theses and Dissertations

We developed an extreme ultraviolet (EUV) polarimeter, which employs laser-generated high-order harmonics as the light source. This relatively high-flux directional EUV source has available wavelengths between 8 nm and 62 nm and easily rotatable linear polarization. The polarimeter will aid researchers at BYU in characterizing EUV thin films and improving their understanding of materials for use in EUV optics. This first-time workhorse application of laser high harmonics enables polarization-sensitive reflection measurements not previously available in the EUV. We have constructed a versatile positioning system that places harmonics on the microchannel plate detector with an accuracy of 0.3 mm, which allows …


Insertion Of Benzylisocyanide Into A Zr-P Bond And Rearrangement. Atom-Economical Synthesis Of A Phosphaalkene, Samantha N. Macmillian, Joseph M. Tanski, Rory Waterman Jul 2007

Insertion Of Benzylisocyanide Into A Zr-P Bond And Rearrangement. Atom-Economical Synthesis Of A Phosphaalkene, Samantha N. Macmillian, Joseph M. Tanski, Rory Waterman

College of Arts and Sciences Faculty Publications

Reaction of (N3N)ZrPHPh (1, N3N = N(CH2CH2NSiMe3)33−) with PhCH2NC affords the 1,1-insertion product (N3N)Zr[C(PHPh)NCH2Ph] (2), which thermally rearranges to the phosphaalkene-containing complex, (N3N)Zr[N(CH2Ph)C(H)PPh] (3).


Super Learner, Mark J. Van Der Laan, Eric C. Polley, Alan E. Hubbard Jul 2007

Super Learner, Mark J. Van Der Laan, Eric C. Polley, Alan E. Hubbard

U.C. Berkeley Division of Biostatistics Working Paper Series

Previous articles (van der Laan and Dudoit (2003); van der Laan et al. (2006); Sinisi et al. (2007)) advertised and theoretically validated the use of cross-validation to select among many candidate estimators to compute a so called super learner which outperforms any of the given candidate estimators. The theoretical basis was provided for this super learner based on oracle results for the cross-validation selector (e.g., van der Laan and Dudoit (2003); van der Laan et al. (2006)) and in Sinisi et al. (2007). In addition, these papers contained a practical demonstration of the adaptivity of this so called super learner …


Reservoir Characterization And Outcrop Analogs To The Navajo Sandstone In The Central Utah Thrust Belt Exploration Play, Ashley Dalrymple Jul 2007

Reservoir Characterization And Outcrop Analogs To The Navajo Sandstone In The Central Utah Thrust Belt Exploration Play, Ashley Dalrymple

Theses and Dissertations

Reservoir heterogeneity plays an important role in oil field economics and completion strategies. We herein characterize the reservoir heterogeneity of the Early Jurassic Navajo Sandstone in the Justensen Flat/Devils Canyon area of the San Rafael Swell, Utah. These outcrops are located approximately 60 kilometers (45 mi) east of the recently discovered Covenant oil field which is located in the central Utah thrust belt exploration play. The reservoir for the Covenant field is the Navajo Sandstone. This study can serve as an outcrop analogue for this developing play and other eolian reservoirs worldwide. There are eight facies within the Navajo Sandstone …


Non-Scalar Economy: An Incentive-Based Approach For Managing Pollution And Attaining Economic Sustainability, Farzad Safaei Jul 2007

Non-Scalar Economy: An Incentive-Based Approach For Managing Pollution And Attaining Economic Sustainability, Farzad Safaei

Faculty of Informatics - Papers (Archive)

In the current economy, the cost of damage to the environment is often external, which is likely to lead to over-exploitation and inadequate provisioning. There are a variety of incentive-based schemes, such as effluent taxes or tradable permits, which attempt to confront the polluting agents with a ‘price’ equal to the marginal external cost of their activity. However, competitive incentives alone are not adequate for effective management of the shared resources. Thus, the current solutions exhibit several drawbacks including susceptibility to international free-riding, sensitivity to accurate estimation of cost of pollution or environmental targets, and inability to take the cumulative …


Sensitivity To Distributional Assumptions In Estimation Of The Odp Thresholding Function, Wendy Jill Bunn Jul 2007

Sensitivity To Distributional Assumptions In Estimation Of The Odp Thresholding Function, Wendy Jill Bunn

Theses and Dissertations

Recent technological advances in fields like medicine and genomics have produced high-dimensional data sets and a challenge to correctly interpret experimental results. The Optimal Discovery Procedure (ODP) (Storey 2005) builds on the framework of Neyman-Pearson hypothesis testing to optimally test thousands of hypotheses simultaneously. The method relies on the assumption of normally distributed data; however, many applications of this method will violate this assumption. This thesis investigates the sensitivity of this method to detection of significant but nonnormal data. Overall, estimation of the ODP with the method described in this thesis is satisfactory, except when the nonnormal alternative distribution has …


Functional Mechanisms Of Motor Skill Acquisition, Ashvin Shah, Andrew G. Barto Jul 2007

Functional Mechanisms Of Motor Skill Acquisition, Ashvin Shah, Andrew G. Barto

Andrew G. Barto

No abstract provided.


Two Chiral Nonet Model With Massless Quarks, Joseph Schechter, Amir H. Fariborz, Renata Jora Jul 2007

Two Chiral Nonet Model With Massless Quarks, Joseph Schechter, Amir H. Fariborz, Renata Jora

Physics - All Scholarship

We present a detailed study of a linear sigma model containing one chiral nonet transforming under U(1)_A as a quark-antiquark composite and another chiral nonet transforming as a diquark-anti diquark composite (or, equivalently from a symmetry point of view, as a two meson molecule). The model provides an intuitive explanation of a current puzzle in low energy QCD: Recent work has suggested the existence of a lighter than 1 GeV nonet of scalar mesons which behave like four quark composites. On the other hand, the validity of a spontaneously broken chiral symmetric description would suggest that these states be chiral …


Exact Results In Model Statistical Systems, Peter H. Kleban Jul 2007

Exact Results In Model Statistical Systems, Peter H. Kleban

University of Maine Office of Research Administration: Grant Reports

This research focuses on the exact study of the statistical mechanics of model systems. Research concentrates on critical percolation in two-dimensions, and important and extensively studied statistical system, and the phase transition of the farey fraction spin chain, a new and interesting one-dimensional model with connections to multifractals and Monte Carol simulations, mathematically exact solutions of model statistical mechanical systems, and techniques from number theory. The goal is to gain new insights into, and understanding of, these systems. An important feature of the project is the use of techniques from pure mathematics and close collaboration with mathematicians.


Linear, Redox Modified Dna Probes As Electrochemical Dna Sensors, Francesco Ricci, Rebecca Lai, Kevin W. Plaxco Jul 2007

Linear, Redox Modified Dna Probes As Electrochemical Dna Sensors, Francesco Ricci, Rebecca Lai, Kevin W. Plaxco

Rebecca Lai Publications

We show here that hybridization-linked changes in the dynamics of a redox-modified, electrode-bound linear (as opposed to stem-loop) probe DNA produce large changes in Faradaic current, allowing for the ready detection of target oligonucleotides.


Take Pride In America In Southern Nevada: Quarterly Progress Report, Period Ending July 05, 2007, Margaret N. Rees Jul 2007

Take Pride In America In Southern Nevada: Quarterly Progress Report, Period Ending July 05, 2007, Margaret N. Rees

Anti-littering Programs

• Don’t Trash Nevada website traffic remains strong despite no separate marketing.

• Project Manager Douglas Joslin attended a by-invitation-only presentation for environmental groups on May 17, 2007 to discuss marketing opportunities with BTDT Enterprises, Inc.

• Mr. Joslin is working with the Clark County School District on elementary educational programs.

• The Anti-Litter Team has started work on a GIS database for littering and dumping data with the GIS Team. The two Teams met twice this quarter to discuss strategy.

• Republic Services’ sponsored Don’t Trash Nevada advertisements, which have begun to run in local newspapers.

• More than …


Haptic Gaze-Tracking Based Perception Of Graphical User Interfaces, Simon Meers, Koren Ward Jul 2007

Haptic Gaze-Tracking Based Perception Of Graphical User Interfaces, Simon Meers, Koren Ward

Faculty of Informatics - Papers (Archive)

This paper presents a novel human-computer interface that enables the computer display to be perceived without any use of the eyes. Our system works by tracking the user's head position and orientation to obtain their 'gaze' point on a virtual screen, and by indicating to the user what object is present at the gaze location via haptic feedback to the fingers and synthetic speech or Braille text. This is achieved by using the haptic vibration frequency delivered to the fingers to indicate the type of screen object at the gaze position, and the vibration amplitude to indicate the screen object's …


Empirical Software Engineering In Industry Short Courses, David S. Janzen, Hossein Saiedian Jul 2007

Empirical Software Engineering In Industry Short Courses, David S. Janzen, Hossein Saiedian

Computer Science and Software Engineering

This paper reports on a pilot project that incorporated small empirical studies in three industry short courses. These laboratory experiments were one component of a larger leveled study on the effects of test-driven development (TDD) on internal software quality. The approach is proposed to have pedagogical value to student-developers by improving their understanding and appreciation for empirical evidence, to instructors by providing feedback through surveys and exercises, and to the community at large by reporting results of the studies. Pre-experiment surveys in the three pilot experiments revealed large differences in programmer opinions of TDD. Possible correlations to development environment and …


Specific Binding Of Mammalian High Mobility Group Protein At-Hook 2 To The Minor Groove Of At-Rich Dnas : Thermodynamic And Specificity Studies, Tengjiao Cui Jul 2007

Specific Binding Of Mammalian High Mobility Group Protein At-Hook 2 To The Minor Groove Of At-Rich Dnas : Thermodynamic And Specificity Studies, Tengjiao Cui

FIU Electronic Theses and Dissertations

The mammalian high mobility group protein AT-hook 2 (HMGA2) is a small transcriptional factor involved in cell development and oncogenesis. It contains three "AT-hook" DNA binding domains, which specifically recognize the minor groove of AT-rich DNA sequences. It also has an acidic C-terminal motif. Previous studies showed that HMGA2 mediates all its biological effects through interactions with AT-rich DNA sequences in the promoter regions. In this dissertation, I used a variety of biochemical and biophysical methods to examine the physical properties of HMGA2 and to further investigate HMGA2's interactions with AT-rich DNA sequences. The following are three avenues perused in …


Extensible Pre-Authentication In Kerberos, Phillip L. Hellewell Jul 2007

Extensible Pre-Authentication In Kerberos, Phillip L. Hellewell

Theses and Dissertations

Organizations need to provide services to a wide range of people, including strangers outside their local security domain. As the number of users grows larger, it becomes increasingly tedious to maintain and provision user accounts. It remains an open problem to create a system for provisioning outsiders that is secure, flexible, efficient, scalable, and easy to manage. Kerberos is a secure, industry-standard protocol. Currently, Kerberos operates as a closed system; all users must be specified upfront and managed on an individual basis. This paper presents EPAK (Extensible Pre-Authentication in Kerberos), a framework that enables Kerberos to operate as an open …


Mechanistic And Structural Studies Of H373q Flavocytochrome B2: Effects Of Mutating The Active Site Base, Chi Lin Tsai, Kuppan Gokulan, Pablo Sobrado, James C. Sacchettini, Paul F. Fitzpatrick Jul 2007

Mechanistic And Structural Studies Of H373q Flavocytochrome B2: Effects Of Mutating The Active Site Base, Chi Lin Tsai, Kuppan Gokulan, Pablo Sobrado, James C. Sacchettini, Paul F. Fitzpatrick

Chemistry Faculty Research & Creative Works

His373 in flavocytochrome b2 has been proposed to act as an active site base during the oxidation of lactate to pyruvate, most likely by removing the lactate hydroxyl proton. The effects of mutating this residue to glutamine have been determined to provide further insight into its role. The kcat and kcat/Klactate values for the mutant protein are 3 to 4 orders of magnitude smaller than the wild-type values, consistent with a critical role for His373. Similar effects are seen when the mutation is incorporated into the isolated flavin domain of the enzyme, narrowing the effects to lactate oxidation rather than …


Directionality In The Wilkinson Microwave Anisotropy Probe Polarization Data, D. Hanson, Douglas Scott, Emory F. Bunn Jul 2007

Directionality In The Wilkinson Microwave Anisotropy Probe Polarization Data, D. Hanson, Douglas Scott, Emory F. Bunn

Physics Faculty Publications

Polarization is the next frontier of cosmic microwave background analysis, but its signal is dominated over much of the sky by foregrounds which must be carefully removed. To determine the efficacy of this cleaning, it is necessary to have sensitive tests for residual foreground contamination in polarization sky maps. The dominant Galactic foregrounds introduce a large-scale anisotropy on to the sky, so it makes sense to use a statistic sensitive to overall directionality for this purpose. Here, we adapt the rapidly computable D statistic of Bunn and Scott to polarization data, and demonstrate its utility as a foreground monitor by …


Parsimonious Classification Via Generalised Linear Mixed Models, G Kauermann, J. T. Ormerod, M P. Wand Jul 2007

Parsimonious Classification Via Generalised Linear Mixed Models, G Kauermann, J. T. Ormerod, M P. Wand

Faculty of Informatics - Papers (Archive)

We devise a classification algorithm based on generalized linear mixed model (GLMM) technology. The algorithm incorporates spline smoothing, additive model-type structures and model selection. For reasons of speed we employ the Laplace approximation, rather than Monte Carlo methods. Tests on real and simulated data show the algorithm to have good classification performance. Moreover, the resulting classifiers are generally interpretable and parsimonious.