Physical Sciences and Mathematics Commons^™

Synthesis, Cellular Studies, And Computational Analysis Of Porphyrin And Bodipy Conjugates With Affinity For Epidermal Growth Factor Receptor, Alecia Michelle Mccall

LSU Doctoral Dissertations

Chapter 1 is a description of the basic fundamental concepts of porphyrins and BODIPYs, (including synthetic methodologies), a general mechanism of the processes of EGFR, and computational concepts that are elaborated upon in future chapters. Chapter 2 is a discussion solely on the porphyrins that were synthesized to be used as fluorophores for EGFR-targeted conjugates, both peptidic and non-peptidic. The porphyrins were primarily synthesized via the Lindsey method as well as by O-alkylation of tetrahydroxy porphyrins. Synthesis of PEG linkages are discussed as well through three methodologies. Chapter 3 is a presentation of the synthesis, characterization, cellular studies, and computational …

Advances In Quantum Optical Metrology And The Establishment Of An Invisible Quantum Tripwire, Steven Blane Mccracken

LSU Doctoral Dissertations

This thesis presents a summary of the foundation and background of the field of quantum optics, and an analysis of some recent discoveries in various fields of which I have aided in furthering investigative research and advancement through publications. Such topics include numerical optimization of generalized quantum states used in phase sensitive quantum metrology, an analysis of object detection through the use of quantum interferometry in the presence of lossy conditions, and the use of the latter technique to propose an invisible quantum tripwire. First is a collaborative effort to numerically optimize quantum optical states for quantum metrological applications. We …

Spring-Block Models Of Earthquake Dynamics, Ashley E. Mccall

All Graduate Theses, Dissertations, and Other Capstone Projects

In this paper, the dynamics of spring-block models are studied. A brief overview of the history of spring-block models relating to earthquakes is presented, along with the development of friction laws. Several mathematical topics relating to dynamical systems are also discussed. We consider two spring-block models; one with Dieterich-Ruina rate and state dependent friction and another with a modified Dieterich-Ruina style friction. For each system, the qualitative behavior and numerical solutions are presented. In the first case, we find that the system undergoes a Hopf bifurcation from a stationary solution to a periodic orbit, and eventually transitions to chaos. In …

Palynomorph And Palynofacies Assemblages Of Neutral-Alkaline And Acid Lakes South Of Norseman, Southern Western Australia, Lutfia Grabel

Masters Theses

"The Yilgarn Craton in Western Australia hosts hundreds of shallow ephemeral hypersaline lakes, the majority of which have acid to neutral pH values. As part of a multidisciplinary study of the evolution of hypersalinity and acidity in the region, three drill cores were studied for their palynofacies and palynomorph contents in order to characterize palynofloral response to environmental changes. Drill cores from two acid lakes, Prado Lake (PL1-09 and PL2-09) and Twin Lake West (TLW1-09), and the neutral-alkaline Gastropod Lake (GLE1-09) south of Norseman recovered Miocene to Holocene sediments of the Revenge and Polar Bear formations. Transmitted light microscopy was …

X-Ray Crystallography For The Study Of Nickel And Iron Salicylaldimines, Carla Schmiesing Eribal

Doctoral Dissertations

"X-ray diffraction of single crystals has developed dramatically over the last century by combining fundamental theories of light, diffraction, and statistics to generate the complete, geometric structure of molecules. The quality of the resulting X -ray structure data are reported in R₁ < 5%, wR2 < 12% and a goodness of fit value of one. This technique was applied specifically to the evaluation of the spin crossover (SCO) compound [Fe(salpm)₂]BF₄ʺ0.5EtOH and how the molecule's geometry changed during a two-step thermal LS-HS conversion. The crystal structure was measured at 100,175,225, and 296 K to yield final R₁ values of 0.047, 0.054, 0.051, and 0.058, respectively. The coordination bond lengths show the spin transitions occur between 100-175K at one crystallographically unique Fe and between 175-225K at the other Fe site. No strong long range interactions are found, suggesting a gradual spin transition. Reaction ofNi(Nalkyl-sal)₂ complexes with Ni(N0₃)₂ form either nickel dimeric, [Ni₃(Rsal)(N0₃)(MeOH)]₂ or trinuclear complexes, Ni₃(Rsal)₄(N0₃)₂. The binuclear complexes, with orthogonal bridging ligands, show overall ferromagnetic interactions. The crystal structures for Ni₃(Rsal)₄(N0₃)₂ from methyl to benzyl were solved and indicate no steric restriction on formation for the series. The trinuclear compounds form an isosceles triangle of metal atoms with the isopropyl analog showing an overall antiferromagnetic interaction with J=+11.386 and J23=-13.891. Lastly, xanthene spirolactam derivatives were structurally analyzed to determine binding modes for their selective and sensitive (µM) detection of metals Cr³⁺, Fe³⁺, Ni²⁺, Co²⁺ and the nerve gas mimic, dichlorophosphate"--Abstract, page iii.

Thermosensitive Magnetic Nanoparticles For Self-Controlled Hyperthermia Cancer Treatment, Karen S. Martirosyan

Physics and Astronomy Faculty Publications and Presentations

Magnetic nanoparticles show remarkable phenomena such as superparamagnetism, high field irreversibility and high saturation magnetization [1]. The study of magnetic nanoparticles has been a very active research field due to many important applications such as drug delivery, imaging and hyperthermia cancer treatment [2]. Hyperthermia has been used for many years to treat a wide variety of tumors in patients and used as well as an adjunct to cancer radiotherapy or chemotherapy [3,4]. Its use is based on the fact that tumor cells are more sensitive to temperature in the range of 42–45°C (which yields necrosis, coagulation, or carbonization) than normal …

Growing Cities Depend On Ecosystem Services, David E. Ervin, Darrell Brown, Heejun Chang, Veronica Dujon, Elise F. Granek, Vivek Shandas, J. Alan Yeakley

Geography Faculty Publications and Presentations

Many studies have documented the growing fragility of a majority of the globe's ecosystems. Policymakers and resource managers often frame such ecosystem challenges as primarily about protecting natural systems in rural areas. However, that conception misses a key part of the story: the rapid growth of urbanizing areas. Home to more than 50 percent of the world's human population for the first time in modern history, urbanizing regions concentrate pressure on ecosystem services, which are necessary to sustain healthy urban living conditions and vibrant commerce. This dramatic urbanization presents both challenges and opportunities for novel ecosystem services management. A transdisciplinary …

An Environmental Systems Analysis Of Hydropower And Its Effects Upon Indigenous Settlements In Karnataka, India, Amy Joens

Honors Program Theses

Hydroelectricity is a very common method of energy production. Large dams are constantly being introduced to the river landscape in areas all over the world. There are definite benefits to hydropower, but the drawbacks may be even more evident. As modernization and development expand across developing nations like India, indigenous populations are often subject to the highest ration of negative impacts and consequences. This research explores both the costs and benefits of hydroelectricity, while using specific examples of dam construction projects to analyze aspects of the cumulative effects of a hydropower project. The Kabini Dam in southern Karnataka, India is …

Extenics In Higher Dimensions, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

Prof. Dr. Florentin Smarandache, during his research period in the Summer of 2012 at

the Research Institute of Extenics and Innovation Methods, from Guangdong University of

Technology, in Guangzhou, China, has introduced the Linear and Non-Linear Attraction

Point Principle and the Network of Attraction Curves, he has generalized the 1D Extension

Distance and the 1D Dependent Function to 2D, 3D, and in general to n-D Spaces, and he

generalized Qiao-Xing Li’s and Xing-Sen Li’s definitions of the Location Value of a Point

and the Dependent Function of a Point on a Single Finite Interval from one dimension (1D) …

Special Quasi Dual Numbers And Groupoids, Florentin Smarandache, W.B. Vasantha Kandasamy

Branch Mathematics and Statistics Faculty and Staff Publications

In this book the authors introduce a new notion called special quasi dual number, x = a + bg.

Among the reals – 1 behaves in this way, for (– 1)2 = 1 = – (– 1). Likewise –I behaves in such a way (– I)2 = – (– I). These special quasi dual numbers can be generated from matrices with entries from 1 or I using only the natural product ×n. Another rich source of these special quasi dual numbers or quasi special dual numbers is Zn, n a composite number. For instance 8 in Z12 is such that …

Fuzzy Linguistic Topological Spaces, Florentin Smarandache, W.B. Vasantha Kandasamy, K. Amal

Branch Mathematics and Statistics Faculty and Staff Publications

No abstract provided.

Neutrosophic Masses & Indeterminate Models Applications To Information Fusion, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this paper we introduce the indeterminate models in information fusion, which are due either to the existence of some indeterminate elements in the fusion space or to some indeterminate masses. The best approach for dealing with such models is the neutrosophic logic.

Modeling And Compressing 3-D Facial Expressions Using Geometry Videos, Jiazhi Xia, Dao T. P. Quynh, Ying He, Xiaoming Chen, Steven C. H. Hoi

Research Collection School Of Computing and Information Systems

In this paper, we present a novel geometry video (GV) framework to model and compress 3-D facial expressions. GV bridges the gap of 3-D motion data and 2-D video, and provides a natural way to apply the well-studied video processing techniques to motion data processing. Our framework includes a set of algorithms to construct GVs, such as hole filling, geodesic-based face segmentation, expression-invariant parameterization (EIP), and GV compression. Our EIP algorithm can guarantee the exact correspondence of the salient features (eyes, mouth, and nose) in different frames, which leads to GVs with better spatial and temporal coherence than that of …

Dynamic Secure Cloud Storage With Provenance, Sherman S. M. Chow, Cheng-Kang Chu, Xinyi Huang, Jianying Zhou, Robert H. Deng

Research Collection School Of Computing and Information Systems

One concern in using cloud storage is that the sensitive data should be confidential to the servers which are outside the trust domain of data owners. Another issue is that the user may want to preserve his/her anonymity in the sharing or accessing of the data (such as in Web 2.0 applications). To fully enjoy the benefits of cloud storage, we need a confidential data sharing mechanism which is fine-grained (one can specify who can access which classes of his/her encrypted files), dynamic (the total number of users is not fixed in the setup, and any new user can decrypt …

Non Associative Linear Algebras, Florentin Smarandache, W.B. Vasantha Kandasamy

Branch Mathematics and Statistics Faculty and Staff Publications

In this book authors for the first time introduce the notion of non associative vector spaces and non associative linear algebras over a field. We construct non associative space using loops and groupoids over fields. In general in all situations, which we come across to find solutions may not be associative; in such cases we can without any difficulty adopt these non associative vector spaces/linear algebras. Thus this research is a significant one.

This book has six chapters. First chapter is introductory in nature. The new concept of non associative semilinear algebras is introduced in chapter two. This structure is …

Detecting Abnormal Behavior In Web Applications, Zi Chu

Dissertations, Theses, and Masters Projects

The rapid advance of web technologies has made the Web an essential part of our daily lives. However, network attacks have exploited vulnerabilities of web applications, and caused substantial damages to Internet users. Detecting network attacks is the first and important step in network security. A major branch in this area is anomaly detection. This dissertation concentrates on detecting abnormal behaviors in web applications by employing the following methodology. For a web application, we conduct a set of measurements to reveal the existence of abnormal behaviors in it. We observe the differences between normal and abnormal behaviors. By applying a …

A Learning-Based Approach To Exploiting Sensing Diversity In Performance Critical Sensor Networks, Matthew Alexander Keally

Dissertations, Theses, and Masters Projects

Wireless sensor networks for human health monitoring, military surveillance, and disaster warning all have stringent accuracy requirements for detecting and classifying events while maximizing system lifetime. to meet high accuracy requirements and maximize system lifetime, we must address sensing diversity: sensing capability differences among both heterogeneous and homogeneous sensors in a specific deployment. Existing approaches either ignore sensing diversity entirely and assume all sensors have similar capabilities or attempt to overcome sensing diversity through calibration. Instead, we use machine learning to take advantage of sensing differences among heterogeneous sensors to provide high accuracy and energy savings for performance critical applications.;In …

Locality Enhancement And Dynamic Optimizations On Multi-Core And Gpu, Zheng Zhang

Dissertations, Theses, and Masters Projects

Enhancing the match between software executions and hardware features is key to computing efficiency. The match is a continuously evolving and challenging problem. This dissertation focuses on the development of programming system support for exploiting two key features of modern hardware development: the massive parallelism of emerging computational accelerators such as Graphic Processing Units (GPU), and the non-uniformity of cache sharing in modern multicore processors. They are respectively driven by the important role of accelerators in today's general-purpose computing and the ultimate importance of memory performance. This dissertation particularly concentrates on optimizing control flows and memory references, at both compilation …

Sublethal Effects Of Methylmercury On The Songbird Immune Response: An Experimental Study, Catherine Ann Lewis

Dissertations, Theses, and Masters Projects

No abstract provided.

Fluorescence Quenching Of Ppv-So And Bodipy-Naphthalene Systems, Brooklynd Dawn Saar

Dissertations, Theses, and Masters Projects

No abstract provided.

Microburst Damage Assessment And Forest Composition Reconstruction After Hurricane Isabel In The College Woods, Williamsburg, Va, Kjarstin Alane Carlson-Drexler

Dissertations, Theses, and Masters Projects

No abstract provided.

New Non-Toxic Holographic Photopolymer Material, Dervil Cody, Izabela Naydenova, Emilia Mihaylova

Articles

There is an increasing need for environmentally friendly holographic recording materials which can be produced in bulk with little risk to the health of workers in manufacturing. This is why the development of non-toxic photopolymer materials is crucial, and has attracted attention in recent years. Composition and preliminary characterization of a new non-toxic photopolymer material are presented. It operates well at a range of spatial frequencies, and achieves diffraction efficiencies and refractive index modulation comparable to the known acrylamide-based photopolymers.

Beta-Diketone And Beta-Ketoenamine Based Molecular Squares, Jackson Kiplagat Cherutoi

LSU Doctoral Dissertations

Abstract This dissertation focuses on synthesis of β-diketone and β-ketoenamine ligands for molecular polygons. Previous work with the bis(β-diketone) m-pbaH2 showed that it can be converted to a copper molecular square, Cu4(m-pba)4, but its use in host-guest reactions was limited by its low solubility in most organic solvents. Accordingly, in the present work, the m-pbhxH2 ligand, with pentyl chains replacing the methyl groups in the β-diketone moieties of m-pbaH2, was successfully prepared beginning with 6-dodecyne. This ligand reacts with Cu2+ to make the molecular square Cu4(m-pbhx)4, which is soluble in a wider range of solvents. Host-guest reactions of Cu4(m-pbhx)4 with …

Elucidation Of B-N And B-P Stretching Vibrations Using Raman Spectroscopy And Electronic Structure Calculations, Dana Nicole Reinemann

Honors Theses

Boron-nitrogen (B-N) and boron-phosphorus (B-P) dative bond stretching vibrational frequencies were studied using vibrational spectroscopic methods and electronic structure calculations. There has been a great controversy over the assignment of B-N dative bond vibrational frequencies for many years with a range of inconsistent assignments in the literature. The B-N dative bond stretching frequency in N-methyliminodiacetic acid (MIDA) esters was analyzed here using infrared, Raman, and surface enhanced Raman spectroscopic methods and compared to the results of electronic structure calculations employing the MP2 and M06-2X methods with a triple zeta basis set. The mode including the B-N stretching motion proved to …

Your Body Is A Temple: Type-2 Diabetes In Mississippi And The Potential Role Of The Black Church In Diabetes Education And Intervention, Jonathon Troy Jackson

Honors Theses

Type-2 diabetes and obesity are two major health complications that are affecting many Mississippians, namely the African American population. A substantial amount of research has been conducted that explains the high prevalence rate of type-2 diabetes and obesity in the African American community as partially due to many secondary factors, including the Southern cuisine, food scarcity, physical inactivity, and poverty. Recently, efforts to reach the African American population about diabetes education and prevention in other Southern states have been directed to faith-based organizations. Researchers have hoped that faith-based intervention might be better suited at helping a wider audience in a …

Design And Analysis Of Cloaked Fluorophores For Rapid Detection And Visualization Of Cancer Cells Containing Nad(P)H:Quinone Oxidoreductase-1, William Silvers

LSU Doctoral Dissertations

The development of fluorogenic substrates for real-time tumor cell detection has led to a vastly expanding field for personal oncology. Fluorophores have been studied as appendages to larger scaffolds leading to accumulation of these dyes in tumor cells or their surrounding environment, taking advantage of tumor anatomy. A new class of fluorophores has been developed in which the dye is an active participant in the mechanism of cancer cell detection. These dyes have been conjugated such that their fluorescence has been eliminated or altered and will undergo a change to reveal their fluorescent signal upon activation by a mechanism that …

Studies Of A Dirhodium Tetraphosphine Catalyst For Hydroformylation And Aldehyde-Water Shift Catalysis, Aaron Rider Barnum

LSU Doctoral Dissertations

Research into the dirhodium tetraphosphine catalyst precursor [rac-Rh2(nbd)2(et,ph-P4)](BF4)2 shows it is capable of forming a highly active and regioselective hydroformylation catalyst in situ when using an acetone or acetone/water solvent. Hydroformylation experiments (using 1-hexene), FT-IR studies, and acid-base studies were performed to better understand the various complexes of the dirhodium catalyst cycle. These studies lead to the newly proposed catalyst mechanism when performed in an acetone/water solution, using the monocationic [rac-Rh2(H)(µ-CO)2(CO) (et,ph-P4)]+ as the proposed active catalyst complex for hydroformylation. For the conversion of 1-hexene to heptanal, it is capable of performing an initial rate of 30 turnovers per min, …

Habitat Use, Movements, And Ecology Of Female Mottled Ducks On The Gulf Coast Of Louisiana And Texas, Bruce Edward Davis

LSU Doctoral Dissertations

Mottled ducks (Anas fulvigula) are the most abundant breeding waterfowl in the coastal marshes of Louisiana and Texas. Mottled ducks are non-migratory and heavily dependent on coastal marsh habitats; they must satisfy all of their annual resource needs from within the Gulf Coast region. Coastal marsh habitats are being rapidly lost or degraded in Louisiana and Texas. The hydrology of many coastal marsh habitats has been altered by anthropogenic activity and natural factors. Parameters related to Mottled Duck habitat use and movements in this altered environment are poorly understood, and managers need information on vital rates of Mottled Ducks in …

Characterization Of Wave Transport In Non-Conservative Media With Random And Correlated Disorder, Benjamin Henry Payne

Doctoral Dissertations

"Passive quasi-one-dimensional random media exhibit one of the three regimes of transport - ballistic, diffusive, or Anderson localization - depending on system size. The ballistic and diffusion approximations assumes particle transport, whereas Anderson Localization occurs when wave self-interference effects are dominant. When the system contains absorption or gain, then how the regimes can be characterized becomes unclear. By investigating theoretically and numerically the ratio of transmission to energy in a random medium in one dimension, we show this parameter can be used to characterize localization in random media with gain. Non-conservative media implies a second dimension for the transport parameter …

Synthesis And Applications Of Imidazolium-Based Ionic Liquids And Their Polymer Derivatives, Woon Su Oh

Doctoral Dissertations

"Imidazolium-based ionic liquids have been increasingly used as green solvents to replace the volatile and relatively toxic organic solvents, in homogeneous and heterogeneous catalysis, materials science, nano materials, lithium ion batteries, and separation technology. Section 1 describes the modulating effect of the imidazolium based room temperature ionic liquids (RTILs) on the critical micelle concentrations (CMC) of surfactants. CMC of sodium dodecyl sulfate (SDS), an anionic surfactant, has been investigated in aqueous solutions of a variety of room temperature ionic liquids (RTILs). CMC values decrease with increasing alkyl chain-length and with fluorinated side chains on the imidazole moiety. In section 2, …