Physical Sciences and Mathematics Commons^™

The Importance Of A Pictorial Medical History In Assisting Medical Diagnosis Of Individuals With Intellectual Disabilities: A Telemedicine Approach, Grace Bonanno

CCE Theses and Dissertations

When face-to-face physical medical exams are not possible, virtual physical exams, in the form of a pictorial medical exam/history, can be substituted, and telemedicine can be the means to deliver these virtual exams. The goal of this work was to determine if presence in the form of a visual and/or pictorial medical history can be of benefit to clinicians in the diagnosis of medical conditions of individuals with developmental disabilities (DDs) and/or intellectual disabilities (IDs), in particular those who cannot, because of their cognitive and/or physical disabilities, verbally relate their illness to a clinician. Virtual exams can also be useful …

Locating Potential Aspect Interference Using Clustering Analysis, Brian Todd Bennett

CCE Theses and Dissertations

Software design continues to evolve from the structured programming paradigm of the 1970s and 1980s and the object-oriented programming (OOP) paradigm of the 1980s and 1990s. The functional decomposition design methodology used in these paradigms reduced the prominence of non-functional requirements, which resulted in scattered and tangled code to address non-functional elements. Aspect-oriented programming (AOP) allowed the removal of crosscutting concerns scattered throughout class code into single modules known as aspects. Aspectization resulted in increased modularity in class code, but introduced new types of problems that did not exist in OOP. One such problem was aspect interference, in which aspects …

Reconciling And Validating The Cloud Thickness And Liquid Water Path Tendencies, Mohamed S. Ghonima, Joel R. Norris, Thijs Heus, Jan Kleissl

Physics Faculty Publications

A detailed derivation of stratocumulus cloud thickness and liquid water path tendencies as a function of the well-mixed boundary layer mass, heat, and moisture budget equations is presented. The derivation corrects an error in the cloud thickness tendency equation derived by R. Wood to make it consistent with the liquid water path tendency equation derived by J. J. van der Dussen et al. The validity of the tendency equations is then tested against the output of large-eddy simulations of a typical stratocumulus-topped boundary layer case and is found to be in good agreement.

Constituent Load Estimation In The Lower Ouachita-Smackover Watershed, Zach P. Simpson, Erin E. Scott, Brian E. Haggard

Technical Reports

Water quality was monitored at 21 sites in the Lower Ouachita‐Smackover Watershed from 2013 November through 2014 September. The U.S. Geological Survey maintains discharge monitoring stations at two of these sites, Moro Creek (USGS 07362500) and Smackover Creek (USGS 07362100), which were sampled during base flow and storm event conditions, whereas the other sites were only sampled during baseflow. The Arkansas Water Resources Center (AWRC) estimated constituent loads for nitrate‐N (NO₃‐–N), total nitrogen (TN), soluble reactive phosphorus (SRP), total phosphorus (TP) and total suspended solids (TSS) using the U.S. Geological Survey LOADEST software. LOADEST creates regression models between constituent concentrations …

Using Kriging, Cokriging, And Gis To Visualize Fe And Mn In Groundwater, Crystal Johnson

Electronic Theses and Dissertations

For aesthetic, economic, and health-related reasons, allowable concentrations of iron (Fe) and manganese (Mn) found present in drinking water are 0.3 mg/L and 0.05 mg/L, respectively. Water samples taken from private drinking wells in the rural communities within Buncombe County, North Carolina contain amounts of these metals in concentrations higher than the suggested limits. This study focused on bedrock geology, elevation, saprolite thickness, and well depth to determine factors affecting Fe and Mn. Using ArcGIS 10.2, spatial trends in Fe and Mn concentrations ranges were visualized, and estimates of the metal concentrations were interpolated to unmonitored areas. Results from this …

Optimized Acid/Base Extraction And Structural Characterization Of Β-Glucan From Saccharomyces Cerevisiae, Shardrack O. Asare

Electronic Theses and Dissertations

β-glucan is a major component of the fungal cell wall consisting of (1→3)-β linked glucose polymers with (1→6)-β linked side chains. The published classical isolation procedure of β-glucan from Saccharomyces cerevisiae is expensive and time-consuming. Thus, the aim of this research was to develop an effective procedure for the extraction of glucans. We have developed a new method for glucan extraction that will be cost effective and will maintain the native structure of the glucan. The method that we developed is 80% faster and utilizes ¹/₃ of the reagents compared to the published classical method. Further, the method …

Investigation Of Mountain Waves In The Mesosphere Over The Andes Mountains, Jaime Aguilar Guerrero

Doctoral Dissertations and Master's Theses

An image processing algorithm has been developed to analyze data from a NIR All-Sky Imager of OH airglow emission (from about 87 km altitude), located in the Andes, with the purpose of investigating the atmospheric gravity waves generated when low level wind blows over the high mountains (referred to as Mountain Waves). These types of waves are a special case of atmospheric gravity waves, which carry significant momentum and exert strong forcing to the background upper atmosphere. The imager is located at the Andes Lidar Observatory (ALO) at Cerro Pachón, Chile (30°S, 71°W), which also houses a Na Doppler Lidar …

A New Approach To Modeling Multivariate Time Series On Multiple Temporal Scales, Tucker Zeleny

Department of Statistics: Dissertations, Theses, and Student Work

In certain situations, observations are collected on a multivariate time series at a certain temporal scale. However, there may also exist underlying time series behavior on a larger temporal scale that is of interest. Often times, identifying the behavior of the data over the course of the larger scale is the key objective. Because this large scale trend is not being directly observed, describing the trends of the data on this scale can be more difficult. To further complicate matters, the observed data on the smaller time scale may be unevenly spaced from one larger scale time point to the …

Chromatographic Analysis Of Drug-Protein Interactions During Diabetes And Characterization Of Human Serum Albumin Through Multidimensional Mass Spectrometry, Ryan E. Matsuda

Department of Chemistry: Dissertations, Theses, and Student Research

Diabetes is a metabolic disease that can lead to the non-enzymatic glycation of serum proteins such as human serum albumin (HSA). Previous studies have indicated that glycation can affect the structure and function of these proteins. This dissertation describes the development of tools and techniques based on high performance affinity chromatography (HPAC) and multidimensional mass spectrometry to analyze the effects of glycation on the function and structure of HSA.

A major portion of this research involved the utilization of HPAC to examine the effect of glycation on the binding of three second-generation sulfonylurea drugs and one third-generation sulfonylurea drug. These …

Analysis Of Free Solute Fractions And Solute-Protein Interactions Using Ultrafast Affinity Extraction And Affinity Microcolumns, Xiwei Zheng

Department of Chemistry: Dissertations, Theses, and Student Research

This dissertation describes the use of a high-performance affinity chromatography method based on ultrafast affinity extraction and microcolumns to study biological interactions.

In the first project, a new method was created and based on ultrafast affinity extraction to determine both the dissociation rate constants (k_d) and association equilibrium constants (K_a) for drug-protein interactions in solution. Various conditions to optimize the use of ultrafast affinity extraction for equilibrium and kinetic studies were considered.

The objective of the next portion of this dissertation was to develop a chromatographic approach to measure free drug fractions in more …

Molecular Mechanism For The Biosynthesis Of Antifungal Hsaf And Antibacterial Wap-8294a2, Haotong Chen

Department of Chemistry: Dissertations, Theses, and Student Research

Bioactive natural products are a major source of anti-infectives. Many ubiquitous inhabitants of soil and water, such as the Gram-negative, prolific producers of natural products, Lysobacter, remain largely unexplored. This PhD thesis reports our studies of the biosynthetic mechanism for a novel antifungal natural product HSAF and a potent anti-MRSA natural product WAP-8294A2.

In the first chapter, we give a short review of the biosynthesis of polyketides, focusing on those which exhibit new biosynthetic features. In subsequent chapters, we present original research on the biosynthetic mechanisms of dihydromaltophilin, a heat stable antifungal factor (HSAF). HSAF is the main antifungal …

Investigations Into The Molecular Mechanisms Of Bacterial Pathogen-Host Interactions: Construction Of A Dual Plasmid System For Incorporation Of Unnatural Amino Acids Into Pseudomonas Syringae Pv. Tomato Dc3000, Scotty D. Raber

Department of Chemistry: Dissertations, Theses, and Student Research

A dual plasmid system for the incorporation of unnatural amino acids into plant pathogen, Pseudomonas syringae pv. tomato DC3000, has been designed. This invention is expected to allow (a) mutations of proteins synthesized by the bacterium, P. syringae pv. tomato DC3000, that can capture molecular targets, especially for such modified proteins secreted by the phytopathogen into the host plant cells of A. thaliana and S. lycopersicum, (b) expression of biological probes in the bacterial species to monitor changes in redox, nutritional, and other small molecule states over pre-, post- and in situ disease stages, and (c) secretion of such …

Stratigraphy And Depositional Environment Of The Mesaverde Group In The Northern Bighorn Basin Of Wyoming, Gordon Adams

Department of Earth and Atmospheric Sciences: Dissertations, Theses, and Student Research

A sedimentological, stratigraphical and palynological study was conducted on the upper Cretaceous (Campanian) Mesaverde Group over 27.5 km of a north-south-orientated outcrop belt in the northern Bighorn Basin, Wyoming. During the Campanian, the study area lay in the western part of the Cretaceous Western Interior Seaway. The study aims to provide a stratigraphic and paleoenvironmental analysis of the Mesaverde Group and to integrate findings with data from outcrop belts to the south (southern Bighorn Basin), north (Montana) and east (Powder River Basin).

The Mesaverde Group (371 - 515 m thick) comprises a succession of mainly coarsening-upward stratal cycles, with some …

Identification, Synthesis And Biological Activity Of Galloyl Inhibitors Of Human Low Molecular Weight Protein Tyrosine Phosphatase, Samuel T. Klinker

Honors Theses, 1963-2015

Low Molecular Weight Protein Tyrosine Phosphatase (LMW-PTP) isoform 2 (IF2) has been found to be over expressed in many forms of aggressive cancer and has become a target for inhibition. Competitive inhibition of LMW-PTP IF2 by known inhibitor pyridoxal-5'-phosphate (PLP) shows a strong inhibition constant (Ki = 7.6 μM at pH 5.0); however, PLP is a cofactor for many other enzymes. In silico screening and in vitro testing identified NSC107022 (Ki = 10.8 ±1.0) from the National Cancer Institute's Diversity Set II as a lead compound for optimization as a LMW-PTP IF2 inhibitor. Utilizing NSC107022's galloyl group, compound libraries of …

Visible And Infrared Spectroelectrochemistry Of Zinc And Manganese Porphinones: Metal Vs. Porphyrin Reduction, Florentina Tutunea, Abderrahman Atifi, Michael D. Ryan

Chemistry Faculty Research and Publications

The visible and infrared spectroelectrochemistry of zinc and manganese porphinones and porphinediones was carried out in THF solutions. The aim of this work was to use FTIR spectroelectrochemistry and DFT calculation to determine whether the reduction was centered predominantly on the metal or the macrocycle. For zinc(II), the first one-electron reduction must occur on the macrocyclic ring because the metal’s d-orbitals are filled (d¹⁰). The carbonyl bands on the macrocyclic ring were used to probe the electronic structure because they can be readily observed in the infrared spectra. The results of this study are complementary to previous spectroelectrochemical …

Measuring Centralities For Transportation Networks Beyond Structures, Yew-Yih Cheng, Lee Ka Wei, Roy, Ee-Peng Lim, Feida Zhu

Research Collection School Of Computing and Information Systems

In an urban city, its transportation network supports efficient flow of people between different parts of the city. Failures in the network can cause major disruptions to commuter and business activities which can result in both significant economic and time losses. In this paper, we investigate the use of centrality measures to determine critical nodes in a transportation network so as to improve the design of the network as well as to devise plans for coping with the network failures. Most centrality measures in social network analysis research unfortunately consider only topological structure of the network and are oblivious of …

Multi-Agent Task Assignment For Mobile Crowdsourcing Under Trajectory Uncertainties, Cen Chen, Shih-Fen Cheng, Hoong Chuin Lau, Archan Misra

Research Collection School Of Computing and Information Systems

In this work, we investigate the problem of mobile crowdsourcing, where workers are financially motivated to perform location-based tasks physically. Unlike current industry practice that relies on workers to manually browse and filter tasks to perform, we intend to automatically make task recommendations based on workers' historical trajectories and desired time budgets. However, predicting workers' trajectories is inevitably faced with uncertainties, as no one will take exactly the same route every day; yet such uncertainties are oftentimes abstracted away in the known literature. In this work, we depart from the deterministic modeling and study the stochastic task recommendation problem where …

Oscar: Online Selection Of Algorithm Portfolios With Case Study On Memetic Algorithms, Mustafa Misir, Stephanus Daniel Handoko, Hoong Chuin Lau

Research Collection School Of Computing and Information Systems

This paper introduces an automated approach called OSCAR that combines algorithm portfolios and online algorithm selection. The goal of algorithm portfolios is to construct a subset of algorithms with diverse problem solving capabilities. The portfolio is then used to select algorithms from for solving a particular (set of) instance(s). Traditionally, algorithm selection is usually performed in an offline manner and requires the need of domain knowledge about the target problem; while online algorithm selection techniques tend not to pay much attention to a careful construction of algorithm portfolios. By combining algorithm portfolios and online selection, our hope is to design …

Rclinker: Automated Linking Of Issue Reports And Commits Leveraging Rich Contextual Information, Tien-Duy B. Le, Mario Linares Vasquez, David Lo, Denys Poshyvanyk

Research Collection School Of Computing and Information Systems

Links between issue reports and their corresponding commits in version control systems are often missing. However, these links are important for measuring the quality of a software system, predicting defects, and many other tasks. Several approaches have been designed to solve this problem by automatically linking bug reports to source code commits via comparison of textual information in commit messages and bug reports. Yet, the effectiveness of these techniques is oftentimes suboptimal when commit messages are empty or contain minimum information; this particular problem makes the process of recovering traceability links between commits and bug reports particularly challenging. In this …

Active Semi-Supervised Defect Categorization, Ferdian Thung, Xuan-Bach D. Le, David Lo

Research Collection School Of Computing and Information Systems

Defects are inseparable part of software development and evolution. To better comprehend problems affecting a software system, developers often store historical defects and these defects can be categorized into families. IBM proposes Orthogonal Defect Categorization (ODC) which include various classifications of defects based on a number of orthogonal dimensions (e.g., symptoms and semantics of defects, root causes of defects, etc.). To help developers categorize defects, several approaches that employ machine learning have been proposed in the literature. Unfortunately, these approaches often require developers to manually label a large number of defect examples. In practice, manually labelling a large number of …

Advances In Knowledge Discovery And Data Mining Part Ii, Tru Cao, Ee Peng Lim, Zhi-Hua Zhou, Tu-Bao Ho, David Wai-Lok Cheung, Hiroshi Motoda

Research Collection School Of Computing and Information Systems

No abstract provided.

Gameon: P2p Gaming On Public Transport, Nairan Zhang, Youngki Lee, Meera Radhakrishnan, Rajesh Krishna Balan

Research Collection School Of Computing and Information Systems

Mobile games, and especially multiplayer games are a very popular daily distraction for many users. We hypothesise that commuters travelling on public buses or trains would enjoy being able to play multiplayer games with their fellow commuters to alleviate the commute burden and boredom. We present quantitative data to show that the typical one-way commute time is fairly long (at least 25 minutes on average) as well as survey results indicating that commuters are willing to play multiplayer games with other random commuters. In this paper, we present GameOn, a system that allows commuters to participate in multiplayer games with …

Flutcha: Using Fluency To Distinguish Humans From Computers, Kotaro Hara, Mohammad Taghi Hajiaghayi, Benjamin B. Benderson

Research Collection School Of Computing and Information Systems

Improvements in image understanding technologies aremaking it possible for computers to pass traditionalCAPTCHA tests with high probability. This suggests theneed for new kinds of tasks that are easy to accomplishfor humans but remain difficult for computers. In thispaper, we introduce Fluency CAPTCHA (FluTCHA), anovel method to distinguish humans from computersusing the fact that humans are better than machines atimproving the fluency of sentences. We propose a wayto let users work on FluTCHA tests and simultaneouslycomplete useful linguistic tasks. Evaluation studiesdemonstrate the feasibility of using FluTCHA todistinguish humans from computers.

Beyond Traits: Social Context Based Personality Model, Jaroslaw Kochanowicz, Ah-Hwee Tan, Daniel Thalmann

Research Collection School Of Computing and Information Systems

The relation between individual’s personality and environmental context is a key issue in psychology, recently also in character simulations. This paper contributes to both domains by proposing a socio-cognitive, contextual personality model - a new voice in a century old problem of personality, but also an approach to simulating groups of more humanlike agents. After analyzing the influence of popularity of ‘trait personality models’ on psychology and computer simulation, we propose Social Context based Personality model - a continuation and specification of the Cognitive-Affective Personality System theory. The discussion, model and implementation are provided, followed by an example application in …

The Requisite Electronic Structure Theory To Describe Photoexcited Nonadiabatic Dynamics: Nonadiabatic Derivative Couplings And Diabatic Electronic Couplings, Joseph E. Subotnik, Ethan Alguire, Qi Ou, Brian R. Landry, Shervin Fatehi

Chemistry Faculty Publications and Presentations

Conspectus

Electronically photoexcited dynamics are complicated because there are so many different relaxation pathways: fluorescence, phosphorescence, radiationless decay, electon transfer, etc. In practice, to model photoexcited systems is a very difficult enterprise, requiring accurate and very efficient tools in both electronic structure theory and nonadiabatic chemical dynamics. Moreover, these theoretical tools are not traditional tools. On the one hand, the electronic structure tools involve couplings between electonic states (rather than typical single state energies and gradients). On the other hand, the dynamics tools involve propagating nuclei on multiple potential energy surfaces (rather than the usual ground state dynamics).

In this …

The Effects Of Instruction On Landing Strategies In Female College-Aged Dancers And Non-Dancers: A Pilot Study, Brittany Keating, Jason Pyfer, Kimberly Vialpando

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background Female athletic participation has increased over the past decade and with it the prevalence of knee injuries. Current research demonstrates an increased risk of anterior cruciate ligament (ACL) injury for female athletes. However, a number of studies have pointed out that ballet and modern dancers exhibit a lower incidence of ACL injuries despite the fact that they perform jumping and landing frequently.

Objective The objective of this study was to examine how dance experience and instruction affect the lower extremity biomechanics during drop landings. Specifically, lower extremity joint alignment and muscle activation of gluteus maximus and gluteus medius were …

The Effects Of Enhanced And Decreased Expectations On Balance Performance In Those With And Without Parkinson’S Disease, Joshua Ostrander, Granuaile Parrish, Jacob Blood

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: It has been reported individuals typically perform well on a task when enhanced expectancy was provided prior to task performance. It has also been reported people with Parkinson’s disease (PD) are especially susceptible to pre-task placebo cuing and suggestion. Evidence of this susceptibility has been previously demonstrated through brain imaging studies and with demonstration by individuals with PD improved balance performance.

Objective: This study was designed to further previous studies’ results for improved task performance with enhanced expectancy. The purpose of this study was to investigate if the pre-task verbal delivery of enhanced expectancy, decreased expectancy and no expectancy …

Enigmatic Rift-Parallel, Strike-Slip Faults Around Eyjafjörður, Northern Iceland, James Arthur Proett

Theses - ALL

Strike-slip faults along mid-ocean ridge and subaerial spreading centers are generally thought to be restricted to transform boundaries connecting rift segments. Faults that are parallel to spreading centers are generally assumed to be normal faults associated with tectonic extension. However, clear evidence of north-south (rift-parallel), strike-slip displacements occur widely around the southern portion of Eyjafjörður, northern Iceland about 50 km west of the actively spreading Northern Rift Zone. The area is south of the southernmost strand (Dalvík Lineament) of the NW-SE-trending, dextral-slip, Tjörnes Fracture Zone (where N-S, sinistral, strike-slip “bookshelf” faulting occurs). Faults in the Eyjafjörður area cut 8.5-10 Ma …

Applications Of Pure And Recycled Polymeric Micro-Nanofiber For The Removal Of Oil Spills., Afra Gharib Khamis Al Blooshi

Theses

Cleaning oil spills is a universal concern due to its environmental impact. The aim of this study is to study the effectiveness and applications of pure and recycled polymers in clean-up and the recovery of crude oil from oil spills. In this study, micro-nanofibres of analytical-grade and commercial polystyrene samples were prepared by electrospinning technique. Fiber size distribution was shown to vary with the electrospinning parameters and type of polymer. Fibrous sorbents prepared hereafter were investigated for their efficiency in removing oil spill. Results showed variation in the sorption capacities of the fibers to various types of crude oils with …

A Slow Neutron Polarimeter For The Measurement Of Parity-Odd Neutron Rotary Power, W. M. Snow, E. Anderson, L. Barron-Palos, C. D. Bass, T. D. Bass, Bret E. Crawford, C. Crawford, J. M. Dawkins, D. Esposito, J. Fry, H. Gardiner, K. Gan, C. Haddock, B. R. Heckel, A. T. Holley, J. C. Horton, C. Huffer, J. Lieffers, D. Luo, M. Maldonado-Velazquez, D. M. Markoff, A. M. Micherdzinska, H. P. Mumm, J. S. Nico, M. Sarsour, S. Santra, E. I. Sharapov, H. E. Swanson, S. B. Walbridge, V. Zhumabekova

Physics and Astronomy Faculty Publications

We present the design, description, calibration procedure, and an analysis of systematic effects for an apparatus designed to measure the rotation of the plane of polarization of a transversely polarized slow neutron beam as it passes through unpolarized matter. This device is the neutronoptical equivalent of a crossed polarizer/analyzer pair familiar from light optics. This apparatus has been used to search for parity violation in the interaction of polarized slow neutrons in matter. Given the brightness of existing slow neutron sources, this apparatus is capable ofmeasuring a neutron rotary power of dϕ/dz = 1 × 10⁻⁷ rad/m.