Physical Sciences and Mathematics Commons^™

Safe Delivery Of Critical Services In Areas With Volatile Security Situation Via A Stackelberg Game Approach, Tien Mai, Arunesh Sinha

Research Collection School Of Computing and Information Systems

Vaccine delivery in under-resourced locations with security risks is not just challenging but also life threatening. The COVID pandemic and the need to vaccinate added even more urgency to this issue. Motivated by this problem, we propose a general framework to set-up limited temporary (vaccination) centers that balance physical security and desired (vaccine) service coverage with limited resources. We set-up the problem as a Stackelberg game between the centers operator (defender) and an adversary, where the set of centers is not fixed a priori but is part of the decision output. This results in a mixed combinatorial and continuous optimization …

Constrained Reinforcement Learning In Hard Exploration Problems, Pankayaraj Pathmanathan, Pradeep Varakantham

Research Collection School Of Computing and Information Systems

One approach to guaranteeing safety in Reinforcement Learning is through cost constraints that are imposed on trajectories. Recent works in constrained RL have developed methods that ensure constraints can be enforced even at learning time while maximizing the overall value of the policy. Unfortunately, as demonstrated in our experimental results, such approaches do not perform well on complex multi-level tasks, with longer episode lengths or sparse rewards. To that end, wepropose a scalable hierarchical approach for constrained RL problems that employs backward cost value functions in the context of task hierarchy and a novel intrinsic reward function in lower levels …

Solving Large-Scale Pursuit-Evasion Games Using Pre-Trained Strategies, Shuxin Li, Xinrun Wang, Youzhi Zhang, Wanqi Xue, Jakub Cerny, Bo An

Research Collection School Of Computing and Information Systems

Pursuit-evasion games on graphs model the coordination of police forces chasing a fleeing felon in real-world urban settings, using the standard framework of imperfect-information extensive-form games (EFGs). In recent years, solving EFGs has been largely dominated by the Policy-Space Response Oracle (PSRO) methods due to their modularity, scalability, and favorable convergence properties. However, even these methods quickly reach their limits when facing large combinatorial strategy spaces of the pursuit-evasion games. To improve their efficiency, we integrate the pre-training and fine-tuning paradigm into the core module of PSRO -- the repeated computation of the best response. First, we pre-train the pursuer's …

Organic–Inorganic Manganese (Ii) Halide Hybrid Combining The Two Isomers Cis/Trans Of [Mncl4(H2o)2]: Crystal Structure, Physical Properties, Pharmacokinetics And Biological Evaluation, Mansoura Bourwina, Sandra Walha, Najeh Krayem, Riadh Badraoui, Faten Brahmi, Mark M. Turnbull, Wejdan M. Alshammari, Mejdi Snoussi, Thierry Roisnel, Houcine Naïli

Chemistry

A manganese (II) complex templated by hexahydro-1,4-diazepinediium as a counter ion was grown by slow evaporation from an aqueous solution at room temperature. The X-ray diffraction analysis revealed that the compound (C₅H₁₄N₂)[MnCl₄(H₂O)₂] crystallizes in the centrosymmetric space group P2/c of the monoclinic system. The crystal structure of the Mn(II) complex is characterized by an alternation of 0-dimensional organic and inorganic stacks linked together by N/O-H…Cl and N-H…O hydrogen bonds, which lead to a three-dimensional supramolecular architecture. In this structure, the inorganic layer is built up by independent anionic …

Working With (Not Against) The Technology: Gpt3 And Artificial Intelligence (Ai) In College Composition, James Hutson, Daniel Plate

Faculty Scholarship

The use of artificial intelligence (AI) for improvement of writing is commonplace with word-processing software and cloudbased writing assistants such as Grammarly and Microsoft Word. However, more and more options are cropping up that move beyond assistance with grammar, spelling, and punctuation to complete essay generation. The free availability of AI essay generators has led to lamenting the coming death of college writing. But AI has been used in the previously noted examples for decades without such a reaction. In fact, the idea that the use of essay generating software is synonymous with academic dishonesty is as passé as worries …

The Use And Challenges Of Spatial Data In Archaeology, Carla Klehm

Anthropology Faculty Publications and Presentations

Spatial data, under the broader umbrella of digital data, is becoming increasingly integral to all stages of archaeological research design and dissemination. As archaeologists lean toward reuse and interoperability, with ethics on their minds, how to treat spatial data is of particular importance. This is because of the complexities involved at every life-cycle stage, from collection to publication, including black box issues that may be taken for granted, and because the size of spatial data can lead to archiving difficulties. Here, the “DIY” momentum of increasingly accessible spatial methods such as photogrammetry and handheld lidar is examined alongside forthcoming changes …

Alignment-Enriched Tuning For Patch-Level Pre-Trained Document Image Models, Lei Wang, Jiabang He, Xing Xu, Ning Liu, Hui Liu

Research Collection School Of Computing and Information Systems

Alignment between image and text has shown promising im provements on patch-level pre-trained document image mod els. However, investigating more effective or finer-grained alignment techniques during pre-training requires a large amount of computation cost and time. Thus, a question natu rally arises: Could we fine-tune the pre-trained models adap tive to downstream tasks with alignment objectives and achieve comparable or better performance? In this paper, we pro pose a new model architecture with alignment-enriched tuning (dubbed AETNet) upon pre-trained document image models, to adapt downstream tasks with the joint task-specific super vised and alignment-aware contrastive objective. Specifically, weintroduce an extra …

The Effects Of Robot Voices And Appearances On Users' Emotion Recognition And Subjective Perception, Sangjin Ko, Jaclyn A. Barnes, Jiayuan Dong, Chung Hyuk Park, Ayanna Howard, Myounghoon Jeon

Michigan Tech Publications

As the influence of social robots in people's daily lives grows, research on understanding people's perception of robots including sociability, trust, acceptance, and preference becomes more pervasive. Research has considered visual, vocal, or tactile cues to express robots' emotions, whereas little research has provided a holistic view in examining the interactions among different factors influencing emotion perception. We investigated multiple facets of user perception on robots during a conversational task by varying the robots' voice types, appearances, and emotions. In our experiment, 20 participants interacted with two robots having four different voice types. While participants were reading fairy tales to …

Effects Of Supply Chain Transparency, Alignment, Adaptability, And Agility On Blockchain Adoption In Supply Chain Among Smes, Mohammad Iranmanesh, Parisa Maroufkhani, Shahla Asadi, Morteza Ghobakhloo, Yogesh K. Dwivedi, Ming-Lang Tseng

Research outputs 2022 to 2026

This study aims to investigate the extent to which the contributions of blockchain technology to supply chain parameters influence blockchain adoption among SMEs. Drawing on contingency theory, the study investigates the moderating effect of market turbulence. The data were collected from 204 SMEs in Malaysia's manufacturing sector and analysed using the partial least squares technique. The results showed that the intention of SMEs’ managers to adopt blockchain is influenced by the contributions of blockchain to supply chain transparency and agility. Supply chain transparency, alignment, adaptability, and agility are interrelated. Market turbulence moderates positively the association between agility and intention to …

Deep Feature Meta-Learners Ensemble Models For Covid-19 Ct Scan Classification, Jibin B. Thomas, K. V. Shihabudheen, Sheik Mohammed Sulthan, Adel Al-Jumaily

Research outputs 2022 to 2026

The infectious nature of the COVID-19 virus demands rapid detection to quarantine the infected to isolate the spread or provide the necessary treatment if required. Analysis of COVID-19-infected chest Computed Tomography Scans (CT scans) have been shown to be successful in detecting the disease, making them essential in radiology assessment and screening of infected patients. Single-model Deep CNN models have been used to extract complex information pertaining to the CT scan images, allowing for in-depth analysis and thereby aiding in the diagnosis of the infection by automatically classifying the chest CT scan images as infected or non-infected. The feature maps …

Synthesis And Biomedical Applications Of Hollow Iron Oxide Nanoparticles, Aloka S. Paragoda Arachchilage

Dissertations, Theses, and Capstone Projects

Nano-scale materials have gained much attention during the past few decades due to the stark differences in their properties compared to bulk material. Thus, they are being studied for a myriad of applications ranging from harnessing solar energy to diagnostics. This thesis focuses on the synthesis of hollow iron oxide nanoparticles using Galvanic replacement reactions and their application in drug delivery. Moreover, the use of a peptide precursor for the enhancement of exosomes is also discussed.

Chapter 1 discusses a simple and economical Galvanic approach used for the synthesis of hollow one-dimensional iron oxide nanotubes. In the initial reaction, the …

Unlocking Potential: The School-To-Prison Pipeline For Students With Disabilities, Navena F. Chaitoo

Dissertations, Theses, and Capstone Projects

This research uses quasi-experimental, matched sampling to examine the school-to-prison pipeline for students with disabilities using data from the National Longitudinal Study of Adolescent to Adult Health. This study presents novel insights into an at-risk group that has faced disproportionate rates of school discipline and incarceration. The study finds school suspension to be associated with future involvement in the criminal legal system and lower educational attainment. Disability was not found to mediate the relationship between suspension and future involvement in the criminal legal system or the relationship between suspension and academic outcomes. However, disability was found to be a statistically …

Dynamics In Designed Elastins And Enzymes, Jonathan M. Preston

Dissertations, Theses, and Capstone Projects

In this dissertation I present experimental results on the structure and dynamics of elastin, an elastomeric extracellular component in vertebrates that, in mammals, provides structure and elasticity to the circulatory system, lungs, skin and joints. These experiments, using a set of designed elastin like proteins with properties analogous to the natural protein, show that elastin is highly disordered and connect this disorder to its mechanism of assembly and elasticity. In addition, I also present preliminary work on imparting flexibility into a set of computationally designed metalloenzymes to broaden the range of catalytic activities they perform.

Synthesis And Analysis Of Novel Troponoid-Based Chemical Probes, Alex Berkowitz

Dissertations, Theses, and Capstone Projects

Troponoids are a class of non-benzenoid aromatic species featuring a cycloheptatrienone ring and varying degrees of oxygenation. These scaffolds have proven ubiquitous amongst natural products, and have displayed promise as therapeutic agents against a variety of diseases. Herein, we will describe our efforts towards furthering troponoids as potential pharmaceuticals. In Chapter 1, we outline a kojic acid-derived oxidopyrylium cycloaddition/ring-opening method developed in our lab to generate ahydroxytropolones (aHTs). This route was successfully adapted to synthesize a small library of lipophilic aHTs that were proven to be effective against herpes simplex virus-1 (HSV-1) replication, while providing further insight into the mechanism …

H-Conise2/Nc Dodecahedral Hollow Structures For High-Performance Supercapacitors, P. Salehan, Ali A. Ensafi, Z. Andikaey, B. Rezaei

Chemistry & Biochemistry Faculty Publications and Presentations

The synergistic effect between metal ions and increasing the surface area leads to the fabrication of supercapacitor materials with high capacities. It is predicted that transition metal selenide compounds will be ideal electrode materials for supercapacitors. However, the defects of poor conductivity and volume expansion of the compounds are fundamental problems that must be solved. In this work, we successfully synthesized the cobalt–nickel selenide nitrogen-doped carbon (H-CoNiSe₂/NC) hollow polyhedral composite structure using ZIF-67 as a precursor. The CoSe₂ and NiSe₂ nanoparticles embedded in the NC polyhedral framework offer a wealth of active sites for the whole …

Diverse Secondary Metabolites Are Expressed In Particle-Associated And Free-Living Microorganisms Of The Permanently Anoxic Cariaco Basin, David Gellar-Mcgrath, Paraskevi Mara, Gordon T. Taylor, Elizabeth A. Suter, Virginia Edgcomb, Maria Pachiadaki

Faculty Works: BCES (1999-2023)

Secondary metabolites play essential roles in ecological interactions and nutrient acquisition, and are of interest for their potential uses in medicine and biotechnology. Genome mining for biosynthetic gene clusters (BGCs) can be used for the discovery of new compounds. Here, we use metagenomics and metatranscriptomics to analyze BGCs in free-living and particle-associated microbial communities through the stratified water column of the Cariaco Basin, Venezuela. We recovered 565 bacterial and archaeal metagenome-assembled genomes (MAGs) and identified 1154 diverse BGCs. We show that differences in water redox potential and microbial lifestyle (particle-associated vs. free-living) are associated with variations in the predicted composition …

Floating Liquid Droplets On The Surface Of Cryogenic Liquids: Implications For Titan Rain, Kendra Farnsworth, Alejandro Soto, Vincent F. Chevrier, Jordan K. Steckloff, Jason M. Soderblom

Space and Planetary Science Faculty Publications and Presentations

Saturn’s moon, Titan, has a hydrocarbon-based hydrologic cycle with methane and ethane rainfall. Because of Titan’s low gravity, “floating liquid droplets” (coherent droplets of liquid hydrocarbons that float upon a liquid surface) may form on the surface of Titan’s hydrocarbon lakes and seas during rainfall. Floating liquid droplets, however, have not been investigated in the laboratory under conditions appropriate for the surface of Titan (cryogenic, hydrocarbon, liquids). We conducted a set of experiments to simulate methane and ethane rainfall under Titan surface conditions (89–94 K, 1.5 bar nitrogen atmosphere) and find that floating ethane droplets form in a wide range …

Dynamic Mass Loss From Greenland's Marine-Terminating Peripheral Glaciers (1985–2018), Katherine E. Bollen, Ellyn M. Enderlin, Rebecca Muhlheim

Geosciences Faculty Publications and Presentations

Global glacier mass balance decreased rapidly over the last two decades, exceeding mass loss from the Greenland and Antarctic Ice Sheets. In Greenland, peripheral glaciers and ice caps (GICs) cover only ~5% of Greenland's area but contributed ~20% of the island's ice mass loss between 2000 and 2018. Although Greenland GIC mass loss due to surface meltwater runoff has been estimated using atmospheric models, mass lost to changes in ice discharge into oceans (i.e., dynamic mass loss) remains unquantified. We use the flux gate method to estimate discharge from Greenland's 585 marine-terminating peripheral glaciers between 1985 and 2018, and compute …

Legal Dispositionism And Artificially-Intelligent Attributions, Jerrold Soh

Research Collection Yong Pung How School Of Law

It is conventionally argued that because an artificially-intelligent (AI) system acts autonomously, its makers cannot easily be held liable should the system's actions harm. Since the system cannot be liable on its own account either, existing laws expose victims to accountability gaps and need to be reformed. Recent legal instruments have nonetheless established obligations against AI developers and providers. Drawing on attribution theory, this paper examines how these seemingly opposing positions are shaped by the ways in which AI systems are conceptualised. Specifically, folk dispositionism underpins conventional legal discourse on AI liability, personality, publications, and inventions and leads us towards …

Bzip Transcription Factors Repress The Expression Of Wheat (Triticum Aestivum L.) High Molecular Weight Glutenin Subunit Genes In Vegetative Tissues, Csaba Éva, Blanka Moncsek, Kitti Szőke-Pázsi, Viola Kunos, Klára Mészáros, Szabolcs Makai, László Sági, Angéla Juhász

Research outputs 2022 to 2026

High molecular weight glutenin subunits (HMW GS) represent an important fraction of endosperm-specific seed-storage proteins that provide elasticity to bread dough. Previously, the second cis-regulatory module (CRM2) was found to be one of the most conserved part of HMW GS promoters, which indicated its pre-eminent role in their gene regulation. Here, we observed that deletion of CRM2 from the promoters of the Bx7 and By8 HMW GS genes increased the leakage of their transient expression in wheat leaf tissue. The effect of a VP1, an Myb and an antisense bZIP transcription factor (TF)-binding site, potentially involved in endosperm-specific regulation within …

The Synapse Issue 35

The Synapse: Intercollegiate science magazine

No abstract provided.

Beam-Based Target Alignment For Mu2e, Helenka Casler

Dissertations, Theses, and Capstone Projects

The Mu2e Experiment is a precision experiment at Fermi National Accelerator Laboratory, searching for charged lepton flavor violation (CLFV) in the conversion of a muon to an electron in the presence of an atomic nucleus. In order to achieve the expected single-event sensitivity of 3 × 10^-17 , Mu2e will require an intense muon beam, generated via pion decay. These pions are the product of a proton beam striking a radiatively-cooled tungsten target. In order to maximize pion production and prevent target failure, the beam will have to be aligned with the target center to within 0.5 mm. The …

Naming Venus: An Exploration Of Goddesses, Heroines, And Famous Women, Kavya Beheraj

Dissertations, Theses, and Capstone Projects

Humans have been observing and romanticizing Venus for more than 5,000 years. However, mapping its surface has nearly always been impossible, since the planet is shrouded in thick clouds. A breakthrough came just fifty years ago with the invention of radar imaging, leading to the discovery (and naming) of hundreds of new features in a relatively short length of time.

The rapid naming of Venus is a case study on the impact of planetary nomenclature — the process of naming features on other worlds. While the act of naming streamlines communication and humanizes alien landscapes, it is subject to bias, …

Engineered Plga Nanofibers For Drug Delivery, Andrew Mancuso

Dissertations, Theses, and Capstone Projects

Poly-lactic-co-glycolic acid (PLGA) polymers are rapidly gaining momentum as a platform for next-generation drug delivery systems due to their ease and low cost of synthesis, favorable biocompatibility and biodegradability, and lack of toxicity. In particular, the application of drug-loaded PLGA nanofibers directly to a target tissue may represent a promising alternative to traditional routes of drug administration (e.g., oral, injectable) as they offer the potential to greatly improve bioavailability, increase efficacy, and reduce off-target toxicity. Furthermore, the use of such a system may potentially allow for greater flexibility in clinical drug development, by enabling the use of compounds which have …

Soil Organic Carbon Dynamics And The Effects Of Resident Vegetation In Pelee Island Soils, Colton Geil

Electronic Thesis and Dissertation Repository

Soil organic carbon (SOC) enhances nutrient retention, structural stability, porosity, aeration, water infiltration, and overall soil health. Understanding SOC turnover and its preservation in soils is paramount to managing carbon sequestration. On Pelee Island, we used δ¹³C, δ¹⁵N and C/N of SOC at various depths to identify the sources and evolution of SOC with time. At depths >150 cm, SOM was from a mixture of aquatic and terrestrially derived sources. We also analyzed the impact of permanent cover crops called ‘resident vegetation’ on the ability of soils to store carbon in different aggregate size fractions. SOC …

Grassland Productivity And Water Quality: A 21st Century Issue, David M. Nash, P. M. Haygarth

IGC Proceedings (1993-2023)

1. Irrigation and other changes to the hydrological cycle can increase soil and water salinity.
2. Primary salinisation is a natural process that affects much of Europe, Asia, Africa, the Americas and Australia. Secondary salinisation is caused by human activities such as irrigation and land clearing that mobilise salt stored in the soil.
3. The critical water contaminants exported from grasslands are nitrogen, phosphorus, potential pathogens and sediment.
4. The mechanisms responsible for diffuse pollution from grasslands and mitigation strategies are most effectively investigated using a ‘source-mobilisation-transport’ framework.
5. There is a lack of coherent interaction across discipline boundaries that links pollutant sources to impact. …

Water Resources, Agriculture And Pasture: Implications Of Growing Demand And Increasing Scarcity, M. W. Rosegrant, R. A. Valmonte-Santos, S. A. Cline, C. Ringler, W. Li

IGC Proceedings (1993-2023)

1. Water availability for irrigation is threatened in many regions by rapidly increasing demand for nonagricultural water uses in industry, households, and the environment. The scarcity of irrigation water will not only impact crop production, but also meat production, as much of the pasture used to feed livestock is irrigated.
2. Grassland is caught between two countervailing forces: a requirement for increasing meat demand that boosts the need for additional pasture to support livestock production, and rapidly increasing water scarcity that makes pasture irrigation uneconomical.
3. The most effective means of dealing with water scarcity is likely to be conserving water in existing …

Soil Quality Assessment And Management, M. G. Kibblewhite

IGC Proceedings (1993-2023)

1. Soil quality is related to the capacity of soil to deliver ecosystem services on a sustainable basis.
2. Effective management of soil within grasslands can deliver many benefits to mankind but poor management may cause loss of soil quality from erosion, loss of organic matter, physical deterioration etc.
3. Services are delivered from soil by biological processes. Soil quality depends on the form and condition of the soil habitat. Fixed factors (e.g. texture) are useful for assigning soil to types. Variable factors (e.g. organic carbon) can then be used to assess quality within soil types, by reference to percentiles of the distribution …

Soil Microbial Community: Understanding The Belowground Network For Sustainable Grassland Management, Y. G. Zhu, W. D. Kong, B. D. Chen, Z. B. Nan, P. Christie

IGC Proceedings (1993-2023)

1. In addition to the use of conventional methodologies in soil microbial research, molecular techniques are now being applied to gain insights into the soil microbial community;
2. Plant diversity can exert impacts on soil microbial diversity (through root activities and plant litter etc.), but may in itself be significantly altered by soil properties;
3. Soil microbial diversity largely determines the stability of soil ecosystems under biotic and abiotic perturbations.
4. Management of soil microbial diversity can only be achieved through better understanding their structures and functions.

Grasslands1 For Production And The Environment, David R. Kemp, David L. Michalk

IGC Proceedings (1993-2023)

1. To manage grasslands for production and enhanced environmental values requires a redefinition of the frameworks within which management decisions are made, and a tailoring of practices to suit the ways that farmers operate.
2. Improving the perenniality and permanence of grasslands usually leads to better environmental and production outcomes.
3. There is a case for a more conservative approach to utilising grasslands in order to sustain the functioning of local ecosystems and to improve water quality, nutrient and energy cycling and biodiversity.
4. A landscape rather than paddock focus is more appropriate for meeting current grassland management objectives. Grasslands can be triaged to …