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Articles 20191 - 20220 of 302503

Full-Text Articles in Physical Sciences and Mathematics

A Survey Of Using Machine Learning In Iot Security And The Challenges Faced By Researchers, Khawlah M. Harahsheh, Chung-Hao Chen Jan 2023

A Survey Of Using Machine Learning In Iot Security And The Challenges Faced By Researchers, Khawlah M. Harahsheh, Chung-Hao Chen

Electrical & Computer Engineering Faculty Publications

The Internet of Things (IoT) has become more popular in the last 15 years as it has significantly improved and gained control in multiple fields. We are nowadays surrounded by billions of IoT devices that directly integrate with our lives, some of them are at the center of our homes, and others control sensitive data such as military fields, healthcare, and datacenters, among others. This popularity makes factories and companies compete to produce and develop many types of those devices without caring about how secure they are. On the other hand, IoT is considered a good insecure environment for cyber …


Social-Engineering, Bio-Economies, And Nation-State Ontological Security: A Commentary, Brandon Griffin, Keitavius Alexander, Xavier-Lewis Palmer, Lucas Potter Jan 2023

Social-Engineering, Bio-Economies, And Nation-State Ontological Security: A Commentary, Brandon Griffin, Keitavius Alexander, Xavier-Lewis Palmer, Lucas Potter

Electrical & Computer Engineering Faculty Publications

Biocybersecurity is an evolving discipline that aims to identify the gaps and risks associated with the convergence of Biology (the science of life and living organisms) and cybersecurity (the science, study, and theory of cyberspace and cybernetics) to protect the bioeconomy. The biological industries’ increased reliance on digitization, automation, and computing power has resulted in benefits for the scientific community, it has simultaneously multiplied the risk factors associated with industrial espionage and the protection of data both commercial and proprietary. The sensitive and potentially destructive power of this data and its access inherently poses a risk to the national and …


A Reflection Of Typology And Verification Flaws In Consideration Of Biocybersecurity/Cyberbiosecurity: Just Another Gap In The Wall, Luke Potter, Kim Mossberg, Xavier Palmer Jan 2023

A Reflection Of Typology And Verification Flaws In Consideration Of Biocybersecurity/Cyberbiosecurity: Just Another Gap In The Wall, Luke Potter, Kim Mossberg, Xavier Palmer

Electrical & Computer Engineering Faculty Publications

Verification is central to any process in a functional and enduring cyber-secure organization. This verification is how the validity or accuracy of a state of being is assessed (Schlick, 1936; Balci, 1998). Conversely, breakdown in verification procedures is core to the interruption of normal operations for an organization. A key problem for organizations that utilize biology as an interlock within their systems is that personnel lack sufficient ability to verify all practically relevant biological information for procedures such as a nurse logging a blood draw, or a molecular biology technician preparing agar to culture microbes for study. This has several …


Detection And Localization Of Data Forgery Attacks In Automatic Generation Control, Fengli Zhang, Yatish R. Dubasi, Wei Bao, Qinghua Li Jan 2023

Detection And Localization Of Data Forgery Attacks In Automatic Generation Control, Fengli Zhang, Yatish R. Dubasi, Wei Bao, Qinghua Li

Electrical Engineering Faculty Publications and Presentations

Automatic Generation Control (AGC) is a key control system to maintain the power system’s balance between load and supply by maintaining its frequency in a specific range. It collects the tie-line power flow and frequency measurements of each control area to calculate the Area Control Error (ACE) and then adjusts power generation based on the calculated ACE. However, malicious frequency or tie-line power flow measurements can be injected and then AGC is misled to make false power generation adjustments which will harm power system operations. Such attacks can be carefully designed to pass the power system’s existing bad data detection …


Multimodal Game-Based Learning In Post-Secondary Education, Nathan A. Vanos Jan 2023

Multimodal Game-Based Learning In Post-Secondary Education, Nathan A. Vanos

EWU Masters Thesis Collection

In this age of unprecedented technological proliferation, educators have been given a unique opportunity to enhance classroom engagement. That opportunity is multimodal game-based learning (MGBL): classroom instruction through a combination of games and multiple modalities of information. Using today’s 3D systems and virtual reality tools, this concept can be explored to depths never before possible. The aim of this project was to design and implement an application that could be used to evaluate how MGBL could impact student engagement and learning, specifically at the post-secondary level. The application implemented during this work was a 3D and virtual reality Simulator for …


New Types Of Soft Sets: Hypersoft Set, Indetermsoft Set, Indetermhypersoft Set, And Treesoft Set, Florentin Smarandache Jan 2023

New Types Of Soft Sets: Hypersoft Set, Indetermsoft Set, Indetermhypersoft Set, And Treesoft Set, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This is a review paper, where we recall the definitions together with practical applications of the Soft Set and its extensions to HyperSoft Set, IndetermSoft Set, IndetermHyperSoft Set, and TreeSoft Set.


Pura Vida Neutrosophic Algebra, Florentin Smarandache, Ranulfo Paiva Barbosa (Sobrinho) Jan 2023

Pura Vida Neutrosophic Algebra, Florentin Smarandache, Ranulfo Paiva Barbosa (Sobrinho)

Branch Mathematics and Statistics Faculty and Staff Publications

We introduce Pura Vida Neutrosophic Algebra, an algebraic structure consisting of neutrosophic numbers equipped with two binary operations namely addition and multiplication. The addition can be calculated sometimes with the function min and other times with the max function. The multiplication operation is the usual sum between numbers. Pura Vida Neutrosophic Algebra is an extension of both Tropical Algebra (also known as Min-Plus, or Min-Algebra) and Max-Plus Algebra (also known as Max-algebra). Tropical and Max-Plus algebras are algebraic structures included in semirings and their operations can be used in matrices and vectors. Pura Vida Neutrosophic Algebra is included in Neutrosophic …


The Use Of Neutrosophic Methods Of Operation Research In The Management Of Corporate Work, Maissam Jdid, Florentin Smarandache Jan 2023

The Use Of Neutrosophic Methods Of Operation Research In The Management Of Corporate Work, Maissam Jdid, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The science of operations research is one of the modern sciences that have made a great revolution in all areas of life through the methods provided by it, suitable and appropriate to solve most of the problems that were facing researchers, scholars and those interested in the development of societies, and the most beneficiaries of this science were companies and institutions that are looking for scientific methods that help them manage their work so that they achieve the greatest profit and the lowest cost, and one of the important methods that have been used in the management of companies we …


On Neutro-La-Semihypergroups And Neutro-Hv-La-Semigroup, Saeid Mirvakili, Akbar Rezaei, Omaima Al-Shanqiti, Florentin Smarandache, Bijan Davvaz Jan 2023

On Neutro-La-Semihypergroups And Neutro-Hv-La-Semigroup, Saeid Mirvakili, Akbar Rezaei, Omaima Al-Shanqiti, Florentin Smarandache, Bijan Davvaz

Branch Mathematics and Statistics Faculty and Staff Publications

In this paper, we extend the notion of LA-semihypergroups (resp. Hv-LA-semigroups) to neutro-LA-semihypergroups (respectively, neutro-Hv-LA-semigroups). Anti-LA-semihypergroups (respectively, anti-Hv-LA-semigroups) are studied and investigated some of their properties. We show that these new concepts are different from classical concepts by several examples. These are particular cases of the classical algebraic structures generalized to neutroalgebraic structures and antialgebraic structures (Smarandache, 2019).


Applications Of Extended Plithogenic Sets In Plithogenic Sociogram, S. Sudha, Nivetha Martin, Florentin Smarandache Jan 2023

Applications Of Extended Plithogenic Sets In Plithogenic Sociogram, S. Sudha, Nivetha Martin, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The theory of plithogeny developed by Smarandache is described as a more generalized form of representing sets of different nature such as crisp, fuzzy, intuitionistic and neutrosophic. Plithogenic set comprises degree of appurtenance and contradiction degree with respect only to the dominant attribute. This paper introduces extended plithogenic sets comprising degrees of appurtenance and contradiction with respect to both dominant and recessive attributes. The extension of the 5-tuple Plithogenic sets to a 7- tuple plithogenic sets helps in developing a more comprehensive kind of Plithogenic sociogram. The newly developed plithogenic sets and its implications in Plithogenic sociogram is validated by …


New Types Of Topologies And Neutrosophic Topologies, Florentin Smarandache Jan 2023

New Types Of Topologies And Neutrosophic Topologies, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this paper we recall the six new types of topologies that we introduced in the last years (2019-2022), such as: Refined Neutrosophic Topology, Refined Neutrosophic Crisp Topology, NeutroTopology, AntiTopology, SuperHyperTopology, and Neutrosophic SuperHyperTopology.


Decision Making Based On Valued Fuzzy Superhypergraphs, Mohammad Hamidi, Florentin Smarandache, Mohadeseh Taghinezhad Jan 2023

Decision Making Based On Valued Fuzzy Superhypergraphs, Mohammad Hamidi, Florentin Smarandache, Mohadeseh Taghinezhad

Branch Mathematics and Statistics Faculty and Staff Publications

This paper explores the defects in fuzzy (hyper) graphs (as complex (hyper) networks) and extends the fuzzy (hyper) graphs to fuzzy (quasi) superhypergraphs as a new concept. We have modeled the fuzzy superhypergraphs as complex superhypernetworks in order to make a relation between labeled objects in the form of details and generalities. Indeed, the structure of fuzzy (quasi) superhypergraphs collects groups of labeled objects and analyzes them in the form of the part to part of objects, the part of objects to the whole group of objects, and the whole to the whole group of objects at the same time. …


Optimal Agricultural Land Use: An Efficient Neutrosophic Linear Programming Method, Maisam Jdid, Florentin Smarandache Jan 2023

Optimal Agricultural Land Use: An Efficient Neutrosophic Linear Programming Method, Maisam Jdid, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The increase in the size of the problems facing humans, their overlap, the division of labor, the multiplicity of departments, as well as the diversity of products and commodities, led to the complexity of business and the emergence of many administrative and production problems. It was necessary to search for appropriate methods to confront these problems. The science of operations research, with its diverse methods, provided the optimal solutions. It addresses many problems and helps in making scientific and thoughtful decisions to carry out the work in the best way within the available capabilities. Operations research is one of the …


On Refined Neutrosophic Finite P-Group, Sunday Adesina Adebisi, Florentin Smarandache Jan 2023

On Refined Neutrosophic Finite P-Group, Sunday Adesina Adebisi, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The neutrosophic automorphisms of a neutrosophic groups G (I) , denoted by Aut(G (I)) is a neu-trosophic group under the usual mapping composition. It is a permutation of G (I) which is also a neutrosophic homomorphism. Moreover, suppose that X1 = X(G (I)) is the neutrosophic group of inner neutrosophic auto-morphisms of a neutrosophic group G (I) and Xn the neutrosophic group of inner neutrosophic automorphisms of Xn-1. In this paper, we show that if any neutrosophic group of the sequence G (I), X1, X2, … is the identity, then G (I) is nilpotent.


Neutrosophic Treatment Of The Modified Simplex Algorithm To Find The Optimal Solution For Linear Models, Florentin Smarandache, Maissam Ahmad Jdid Jan 2023

Neutrosophic Treatment Of The Modified Simplex Algorithm To Find The Optimal Solution For Linear Models, Florentin Smarandache, Maissam Ahmad Jdid

Branch Mathematics and Statistics Faculty and Staff Publications

Science is the basis for managing the affairs of life and human activities, and living without knowledge is a form of wandering and a kind of loss. Using scientific methods helps us understand the foundations of choice, decision-making, and adopting the right solutions when solutions abound and options are numerous. Operational research is considered the best that scientific development has provided because its methods depend on the application of scientific methods in solving complex issues and the optimal use of available resources in various fields, private and governmental work in peace and war, in politics and economics, in planning and …


The Fluid Margin Between Physical Causal Closure And Non-Physical Causal Closure, Extended To The Neutrosophic Causal Closure Principle, Florentin Smarandache Jan 2023

The Fluid Margin Between Physical Causal Closure And Non-Physical Causal Closure, Extended To The Neutrosophic Causal Closure Principle, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

We plead for a fluid margin, or mixed/indeterminate buffer zone, between Physical and Non-Physical Causal Closures, and for a Neutrosophic Causal Closure Principle claiming that the chances of all physical effects are determined by their prior partially physical and partially non-physical causes.


Remark On Regenerative Medicine And Potential Utilization Of Low-Intensity Laser Photobiomodulation To Activate Human Stem Cells, Victor Christianto, Florentin Smarandache, Robert N. Boyd Jan 2023

Remark On Regenerative Medicine And Potential Utilization Of Low-Intensity Laser Photobiomodulation To Activate Human Stem Cells, Victor Christianto, Florentin Smarandache, Robert N. Boyd

Branch Mathematics and Statistics Faculty and Staff Publications

Recently, a friend of one of these writers told her story of using one of a healthcare product to activate her stem cells as part of regenerative medicine. Regenerative medicine is a field of medicine that seeks to repair or replace damaged or diseased tissues and organs. This can be done through a variety of methods, including stem cell therapy, tissue engineering, and gene therapy. This is a short review article on this rapid field called regenerative medicine, in particular via a new method called photobiomodulation, especially by virtue of low-intensity laser pen treatment. Hopefully it will attract more research …


On Characterizing Efficient And Properly Efficient Solutions For Multi- Objective Programming Problems In A Complex Space, Alhanouf Alburaikan, Hamiden Abd El-Wahed Khalifa, Florentin Smarandache Jan 2023

On Characterizing Efficient And Properly Efficient Solutions For Multi- Objective Programming Problems In A Complex Space, Alhanouf Alburaikan, Hamiden Abd El-Wahed Khalifa, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this paper, a complex non- linear programming problem with the two parts (real and imaginary) is considered. The efficient and proper efficient solutions in terms of optimal solutions of related appropriate scalar optimization problems are characterized. Also, the Kuhn-Tuckers' conditions for efficiency and proper efficiency are derived. This paper is divided into two independently parts: The first provides the relationships between the optimal solutions of a complex single-objective optimization problem and solutions of two related real programming problems. The second part is concerned with the theory of a multi-objective optimization in complex space.


Higher-Degree Asymptotes Of A Rational-Polynomial Function, Florentin Smarandache Jan 2023

Higher-Degree Asymptotes Of A Rational-Polynomial Function, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

By a straight-forward method we extend the horizontal and slant asymptotes to the higher -degree asymptotes of a function, and we give several examples and prove a theorem.


Another Way To Divide Two Complex Numbers: Identification Method, Florentin Smarandache Jan 2023

Another Way To Divide Two Complex Numbers: Identification Method, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In this short note to design another method to divide two complex numbers and present a numerical example.


S-Methyl Cysteine Sulfoxide And Its Potential Role In Human Health: A Scoping Review, Caroline R. Hill, Alex Haoci Liu, Lyn Mccahon, Liezhou Zhong, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst Jan 2023

S-Methyl Cysteine Sulfoxide And Its Potential Role In Human Health: A Scoping Review, Caroline R. Hill, Alex Haoci Liu, Lyn Mccahon, Liezhou Zhong, Armaghan Shafaei, Lois Balmer, Joshua R. Lewis, Jonathan M. Hodgson, Lauren C. Blekkenhorst

Research outputs 2022 to 2026

Higher intakes of cruciferous and allium vegetables are associated with a lower risk of cardiometabolic-related outcomes in observational studies. Whilst acknowledging the many healthy compounds within these vegetables, animal studies indicate that some of these beneficial effects may be partially mediated by S-methyl cysteine sulfoxide (SMCSO), a sulfur-rich, non-protein, amino acid found almost exclusively within cruciferous and alliums. This scoping review explores evidence for SMCSO, its potential roles in human health and possible mechanistic action. After systematically searching several databases (EMBASE, MEDLINE, SCOPUS, CINAHL Plus Full Text, Agricultural Science), we identified 21 original research articles meeting our inclusion criteria. These …


Investigation Of Oleic Acid As A Dispersant For Hydroxyapatite Powders For Use In Ceramic Filled Photo-Curable Resins For Stereolithography, Brendan Kennedy, Eamonn De Barra, Stuart Hampshire, Maura Kelleher Jan 2023

Investigation Of Oleic Acid As A Dispersant For Hydroxyapatite Powders For Use In Ceramic Filled Photo-Curable Resins For Stereolithography, Brendan Kennedy, Eamonn De Barra, Stuart Hampshire, Maura Kelleher

Articles

Stereolithography allows production of porous hydroxyapatite scaffolds for bone regeneration but is limited by the challenging rheology of ceramic filled resins. Oleic acid, a natural fatty acid, was applied in concentrations of 0.0–0.3 wt% to improve the rheological properties of HAp resins for the fabrication of solid cylinders and scaffolds by digital light processing (DLP) printing in a wiperless system. Bonding by chemisorption was confirmed by FTIR analysis. The powders were then incorporated into a photo-curable resin of 1–6 hexanediol diacrylate at 18–30 vol%. The shear viscosity and sedimentation rates of photocurable resins containing HAp powder decreased with increasing concentration …


Clear: Spatially Resolved Emission Lines And Active Galactic Nuclei At 0.6 < Z < 1.3, Bren E. Backhaus, Joanna S. Bridge, Jonathan R. Trump, Nikko J. Cleri, Casey Papovich, Raymond C. Simons, Ivelina Momcheva, Benne Holwerda, Zhiyuan Ji, Intae Jung, Jasleen Matharu Jan 2023

Clear: Spatially Resolved Emission Lines And Active Galactic Nuclei At 0.6 < Z < 1.3, Bren E. Backhaus, Joanna S. Bridge, Jonathan R. Trump, Nikko J. Cleri, Casey Papovich, Raymond C. Simons, Ivelina Momcheva, Benne Holwerda, Zhiyuan Ji, Intae Jung, Jasleen Matharu

Faculty and Staff Scholarship

We investigate spatially resolved emission-line ratios in a sample of 219 galaxies (0.6 < z < 1.3) detected using the G102 grism on the Hubble Space Telescope Wide Field Camera 3 taken as part of the CANDELS Lyα Emission at Reionization survey to measure ionization profiles and search for low-luminosity active galactic nuclei (AGN). We analyze [O III] and Hβ emission-line maps, enabling us to spatially resolve the [O III]/Hβ emission-line ratio across the galaxies in the sample. We compare the [O III]/Hβ ratio in galaxy centers and outer annular regions to measure ionization differences and investigate the potential of sources with nuclear ionization to host AGN. We investigate some of the individual galaxies that are candidates to host strong nuclear ionization and find that they often have low stellar mass and are undetected in X-rays, as expected for low-luminosity AGN in low-mass galaxies. We do not find evidence for a significant population of off-nuclear AGN or other clumps of off-nuclear ionization. We model the observed distribution of [O III]/Hβ spatial profiles and find that most galaxies are consistent with a small or zero difference between their nuclear and off-nuclear line ratios, but 6%–16% of galaxies in the sample are likely to host nuclear [O III]/Hβ that is ∼0.5 dex higher than in their outer regions. This study is limited by large uncertainties in most of the measured [O III]/Hβ spatial profiles; therefore, deeper data, e.g., from deeper HST/ WFC3 programs or from JWST/NIRISS, are needed to more reliably measure the spatially resolved emission-line conditions of individual high-redshift galaxies.


Environmental Health Justice Across The Globe, Arnita Gadson, Rochelle H. Holm Jan 2023

Environmental Health Justice Across The Globe, Arnita Gadson, Rochelle H. Holm

Faculty and Staff Scholarship

No abstract provided.


Synthesis And Characterization Of Polymer Grafted Nanoparticles, Eric Gerald Ruzicka Jan 2023

Synthesis And Characterization Of Polymer Grafted Nanoparticles, Eric Gerald Ruzicka

Theses and Dissertations

This dissertation focuses on the design, synthesis, and characterization of well controlled interfaces on nanoparticle surfaces. Reversible addition-fragmentation chain transfer (RAFT) polymerization was used to synthesize block copolymers and polymer grafted silica nanoparticles (PGNs) with precise control over molecular weight, graft density, and architectures.

In the first chapter, polymer molecular weights were determined through diffusion ordered spectroscopy NMR (DOSY NMR) as an alternative to size exclusion chromatography (SEC). Polymer standards of known molecular weight were analyzed through DOSY to obtain their respective diffusion coefficients. A calibration curve was generated correlating diffusion coefficients with polymer molecular weights. The reliability of the …


Knowledge Discovery On The Integrative Analysis Of Electrical And Mechanical Dyssynchrony To Improve Cardiac Resynchronization Therapy, Zhuo He Jan 2023

Knowledge Discovery On The Integrative Analysis Of Electrical And Mechanical Dyssynchrony To Improve Cardiac Resynchronization Therapy, Zhuo He

Dissertations, Master's Theses and Master's Reports

Cardiac resynchronization therapy (CRT) is a standard method of treating heart failure by coordinating the function of the left and right ventricles. However, up to 40% of CRT recipients do not experience clinical symptoms or cardiac function improvements. The main reasons for CRT non-response include: (1) suboptimal patient selection based on electrical dyssynchrony measured by electrocardiogram (ECG) in current guidelines; (2) mechanical dyssynchrony has been shown to be effective but has not been fully explored; and (3) inappropriate placement of the CRT left ventricular (LV) lead in a significant number of patients.

In terms of mechanical dyssynchrony, we utilize an …


Exploring Different Mediums For Teaching Programming And Cybersecurity In Primary And Secondary Schools, Andrew R. Youngstrom Jan 2023

Exploring Different Mediums For Teaching Programming And Cybersecurity In Primary And Secondary Schools, Andrew R. Youngstrom

Dissertations, Master's Theses and Master's Reports

Cybersecurity and programming are becoming more and more prominent in today’s world. It is beneficial to begin teaching these topics to students at a younger age. Additionally, we see students in primary and secondary schools struggling to maintain focus in class as attention spans shrink. This paper looks at different drone models to see if any of them could be sufficient solutions to be implemented into primary and secondary schools to teach cybersecurity and programming topics to students. Besides teaching capabilities, drones must also be affordable for institutions and simple enough to construct, configure, and operate so that a teacher …


An Ambiguous Technique For Nonvisual Text Entry, Dylan C. Gaines Jan 2023

An Ambiguous Technique For Nonvisual Text Entry, Dylan C. Gaines

Dissertations, Master's Theses and Master's Reports

Text entry is a common daily task for many people, but it can be a challenge for people with visual impairments when using virtual touchscreen keyboards that lack physical key boundaries. In this thesis, we investigate using a small number of gestures to select from groups of characters to remove most or all dependence on touch locations. We leverage a predictive language model to select the most likely characters from the selected groups once a user completes each word.

Using a preliminary interface with six groups of characters based on a Qwerty keyboard, we find that users are able to …


Mealybug Vectors: A Review Of Their Transmission Of Plant Viruses And Their Management Strategies, Abdul Razak Ahmed, Samuel Obeng Apori, Abdul Aziz Karim Jan 2023

Mealybug Vectors: A Review Of Their Transmission Of Plant Viruses And Their Management Strategies, Abdul Razak Ahmed, Samuel Obeng Apori, Abdul Aziz Karim

Articles

Mealybugs cause mechanical damage and diseases to plants. Through their feeding activities, they reduce the yield, quality and productivity of crops. This review discusses mealybug vectors of plant viruses, the economic losses they cause, mealybug species and their hosts. Among the numerous mealybug species, Planococcus species are the most effective vector of plant viruses, transmitting many Ampeloviruses. Diverse methods for the control and regulation of mealybugs are also discussed. Physical, cultural and biological control methods are labor-intensive but environmentally friendly compared to chemical methods. However, chlorpyrifos are one the active ingredients of insecticides effective against several mealybug species. Using plant …


Structural And Functional Modulation Of Metal-Organic Supercontainers (Moscs) And Their Applications In Supramolecular Catalysis, Shrijana Dc Jan 2023

Structural And Functional Modulation Of Metal-Organic Supercontainers (Moscs) And Their Applications In Supramolecular Catalysis, Shrijana Dc

Dissertations and Theses

Metal-organic supercontainers (MOSCs), a breakthrough development in our laboratory since 2012, have emerged as promising enzyme mimics, showcasing their prowess in encapsulating guest molecules and catalyzing confined chemical reactions. The intrigue surrounding MOSCs stems from their extraordinary traits, encompassing multiple binding domains, high stability, large surface area, tunable pore size, and structural modularity. Primarily comprising sulfonylcalix[4]arenes, divalent metal ions, and carboxylate linkers, MOSCs' quintessential architecture comprises both endo- and exo- nano-cavities, amenable to guest interaction, with geometry and functionality manipulation achievable through precise precursor selection. Nonetheless, early MOSC models exhibit limited reactivity, often necessitating more potent nucleophiles or electrophiles. This …