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Full-Text Articles in Physical Sciences and Mathematics

The Simulated Sensitivity Of The North American Monsoon At Convection-Permitting Scales, Brendan Wallace Dec 2022

The Simulated Sensitivity Of The North American Monsoon At Convection-Permitting Scales, Brendan Wallace

Legacy Theses & Dissertations (2009 - 2024)

The North American Monsoon (NAM) is a major contributor to annual rainfall for large portions of the North American Southwest. Much of the prior work examining the NAM using numerical models has been done at scales exceeding 20-km grid spacing. At these coarse scales, unresolved processes and poorly resolved geographic features can impact model performance. This can present a problem when simulating the NAM particularly with regard to orographic precipitation, precipitation on sub-daily timescales, and land surface-atmosphere interactions. This dissertation seeks to better understand the NAM through examination of several sets of convection-permitting regional climate model output. The primary goal …


Voting Rules And Properties, Zhuorong Mao Dec 2022

Voting Rules And Properties, Zhuorong Mao

Undergraduate Honors Theses

This thesis composes of two chapters. Chapter one considers the higher order of Borda Rules (Bp) and the Perron Rule (P) as extensions of the classic Borda Rule. We study the properties of those vector-valued voting rules and compare them with Simple Majority Voting (SMV). Using simulation, we found that SMV can yield different results from B1, B2, and P even when it is transitive. We also give a new condition that forces SMV to be transitive, and then quantify the frequency of transitivity when it fails.

In chapter two, we study the `protocol paradox' of approval voting. In approval …


Post Pandemic Cyberbiosecurity Threats From Terrorist Groups, Haley D. Dodge Dec 2022

Post Pandemic Cyberbiosecurity Threats From Terrorist Groups, Haley D. Dodge

Master's Theses

The research in this thesis explored the research question: Are United States (US) health systems accessible to cyber-bio terrorist attacks post-pandemic, within the context of the emerging discipline of cyberbiosecurity? Key findings of the analysis demonstrated how US health systems are more accessible to cyber-bio terrorist attacks specifically from cyber hacking groups based on the increasing sophistication of their cyber capabilities and the lack of cyber protection for biological systems. The concept of cyberbiosecurity was first introduced in 2018 by researchers exploring the converging threat landscape of the cyber and biology domains. As biology is growing more dependent upon vulnerable …


Evaluation Of Distributed Programming Models And Extensions To Task-Based Runtime Systems, Yu Pei Dec 2022

Evaluation Of Distributed Programming Models And Extensions To Task-Based Runtime Systems, Yu Pei

Doctoral Dissertations

High Performance Computing (HPC) has always been a key foundation for scientific simulation and discovery. And more recently, deep learning models' training have further accelerated the demand of computational power and lower precision arithmetic. In this era following the end of Dennard's Scaling and when Moore's Law seemingly still holds true to a lesser extent, it is not a coincidence that HPC systems are equipped with multi-cores CPUs and a variety of hardware accelerators that are all massively parallel. Coupling this with interconnect networks' speed improvements lagging behind those of computational power increases, the current state of HPC systems is …


(R1978) Heated Laminar Vertical Jet Of Psudoplastic Fluids-Against Gravity, Manisha Patel, M. G. Timol Dec 2022

(R1978) Heated Laminar Vertical Jet Of Psudoplastic Fluids-Against Gravity, Manisha Patel, M. G. Timol

Applications and Applied Mathematics: An International Journal (AAM)

A heated laminar jet of Pseudo-plastic fluid flowing vertically upwards from a long narrow slit into a region of the same fluid which is at a rest and at a uniform temperature is considered. The governing non-linear Partial differential equations (PDEs) for the defined flow problem are transformed into non-linear ordinary differential equations using the effective similarity technique-one parameter deductive group theory method. The obtained non-linear coupled Ordinary differential equations are solved and the results are presented by graphs. The effect of the Prandtl number and Grashof number on the velocity and temperature of the jet flow is discussed. Also, …


(R1985) Study The Effect Of Modified Newtonian Force On The Restricted 3-Body Configuration In Non-Linear Sense, Bhawna Singh, Kumari Shalini, Sada Nand Prasad, Abdullah A. Ansari Dec 2022

(R1985) Study The Effect Of Modified Newtonian Force On The Restricted 3-Body Configuration In Non-Linear Sense, Bhawna Singh, Kumari Shalini, Sada Nand Prasad, Abdullah A. Ansari

Applications and Applied Mathematics: An International Journal (AAM)

This paper aims to investigate the non-linear stability of the triangular libration point in the restricted three-body problem (R3BP). The model, we use for our problem consists of a primary body as a heterogeneous spheroid with N-layers having different densities of each layer and a secondary body as a point mass that is producing the modified Newtonian Potential. We determine the equation of motion of the smallest body which is under the influence of the above-mentioned perturbations and also influenced by Coriolis as well as Centrifugal forces and then evaluated the Lagrangian for the evaluated system of equations. Afterwards, we …


(R1980) Effect Of Climate Change On Brain Tumor, Pardeep Kumar, Sarita Jha, Rajiv Aggarwal, Govind Kumar Jha Dec 2022

(R1980) Effect Of Climate Change On Brain Tumor, Pardeep Kumar, Sarita Jha, Rajiv Aggarwal, Govind Kumar Jha

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, we introduce a new dynamical model addressing the variation in climate condition due the presence of microorganisms. We also introduce a new dynamical model of cancer growth which includes three interactive cell populations with drug free environment, namely tumor cells, healthy host cells, and immune effector cells. In this, we considered the super growth of tumor cells. For the choice of certain parameters, both of the systems exhibit chaotic behavior. The aim of this work is to design the controller to control the chaos and to provide sufficient conditions which achieve synchronization of two non-identical systems, which …


(R2022) Mathematical Modelling Of Tuberculosis And Covid-19 Co-Infection In India: A Real Data Analysis On Concomitant Diseases, Vijai Shanker Verma, Harshita Kaushik, Archana Singh Bhadauria Dec 2022

(R2022) Mathematical Modelling Of Tuberculosis And Covid-19 Co-Infection In India: A Real Data Analysis On Concomitant Diseases, Vijai Shanker Verma, Harshita Kaushik, Archana Singh Bhadauria

Applications and Applied Mathematics: An International Journal (AAM)

In this paper, we have proposed an epidemiological model to study the dynamics of two concomitant diseases Tuberculosis (TB) and COVID-19. Here, we have formulated a deterministic compartmental model as an extended form of the classical SIS model. First, the basic reproduction number R0 is derived and then stability analysis of the model is done. It is observed that the disease-free equilibrium is stable when R0 is less than one and the endemic equilibrium is stable only when R0 is greater than one. Numerical simulation is carried out to illustrate the theoretical findings and to study the …


Financial Literacy Among Buffalo State College Undergraduate Students, Toni Martinucci Dec 2022

Financial Literacy Among Buffalo State College Undergraduate Students, Toni Martinucci

Public Administration Master’s Projects

Financial literacy can be complex and difficult for college students to comprehend. Many students struggle to afford college and are faced with large amounts of student loan debt. Financial awareness needs to be addressed early on for students to make informed decisions about college costs, student debt, and financial aid. However, financial aid applications, terms and conditions, and eligibility requirements are difficult for many students to comprehend on their own. The purpose of this study is to access financial literacy among undergraduate students at Buffalo State College. A quantitative approach is used in this study by implementing a web-based cross-sectional …


Disease Recognition In X-Ray Images With Doctor Consultation-Inspired Model, Kim Anh Phung, Thuan Trong Nguyen, Nileshkumar Wangad, Samah Baraheem, Nguyen D. Vo, Khang Nguyen Dec 2022

Disease Recognition In X-Ray Images With Doctor Consultation-Inspired Model, Kim Anh Phung, Thuan Trong Nguyen, Nileshkumar Wangad, Samah Baraheem, Nguyen D. Vo, Khang Nguyen

Computer Science Faculty Publications

The application of chest X-ray imaging for early disease screening is attracting interest from the computer vision and deep learning community. To date, various deep learning models have been applied in X-ray image analysis. However, models perform inconsistently depending on the dataset. In this paper, we consider each individual model as a medical doctor. We then propose a doctor consultation-inspired method that fuses multiple models. In particular, we consider both early and late fusion mechanisms for consultation. The early fusion mechanism combines the deep learned features from multiple models, whereas the late fusion method combines the confidence scores of all …


Denoising And Deconvolving Sperm Whale Data In The Northern Gulf Of Mexico Using Fourier And Wavelet Techniques, Kendal Mccain Leftwich Dec 2022

Denoising And Deconvolving Sperm Whale Data In The Northern Gulf Of Mexico Using Fourier And Wavelet Techniques, Kendal Mccain Leftwich

University of New Orleans Theses and Dissertations

The use of underwater acoustics can be an important component in obtaining information from the oceans of the world. It is desirable (but difficult) to compile an acoustic catalog of sounds emitted by various underwater objects to complement optical catalogs. For example, the current visual catalog for whale tail flukes of large marine mammals (whales) can identify even individual whales from their individual fluke characteristics. However, since sperm whales, Physeter microcephalus, do not fluke up when they dive, they cannot be identified in this manner. A corresponding acoustic catalog for sperm whale clicks could be compiled to identify individual …


Bedrock Geology Map Of The Naomi Peak 7.5' Quadangle, Cache County, Utah And Novel Age Constraints On Its Cambrian Strata, Hannah R. Cothren Dec 2022

Bedrock Geology Map Of The Naomi Peak 7.5' Quadangle, Cache County, Utah And Novel Age Constraints On Its Cambrian Strata, Hannah R. Cothren

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Geologists use various “rock-clocks” in order to interpret the timing and tempo of events in Earth’s history. These include global geochemical events in the oceans (chemostratigraphy), the evolution of certain fossil species (trilobite biostratigraphy), and the radiogenic decay of uranium to lead in certain mineral such as zircon (U-Pb geochronology). Integrating these methods in the stratigraphic record in one location can provide a well-constrained timeline for a select part of the Geologic, or Deep Time, record. This technique is especially important in the Cambrian Period (538.8 to 486.9 million years; Ma), which sets the stage for life today with the …


Veratrum Parviflorum Poisoning: Identification Of Steroidal Alkaloids In Patient Blood And Breast Milk, Jared T. Seale, Xinzhu Pu, Owen M. Mcdougal Dec 2022

Veratrum Parviflorum Poisoning: Identification Of Steroidal Alkaloids In Patient Blood And Breast Milk, Jared T. Seale, Xinzhu Pu, Owen M. Mcdougal

Chemistry and Biochemistry Faculty Publications and Presentations

Introduction

The Veratrum genus is composed of plants containing a diverse set of steroidal alkaloids. Veratrum plant material has been utilized for centuries as herbal medicines, however the alkaloids have such a low therapeutic index that they are not used in modern medicine. Here we report an incident of inadvertent ingestion of V. parviflorum by hikers in Georgia that allowed detection, and in several instances identification of alkaloids from the plant, and correlated their presence within patient blood and breast milk specimens.

Case history

Eight patients, three male and five female, presented in the spring of 2020 and 2021 with …


On Interpreting Eddy Covariance In Small Area Agricultural Situations With Contrasting Site Management., Joel Oetting Dec 2022

On Interpreting Eddy Covariance In Small Area Agricultural Situations With Contrasting Site Management., Joel Oetting

Doctoral Dissertations

This dissertation examined the carbon sequestration potential of a low C:N soil amendment and its incorporation into the soil over a rolling agricultural field. A segmented planar fit was developed to assess and correct the systematic errors the topography introduces on the carbon dioxide fluxes. The carbon dioxide fluxes were then be partitioned into gross primary productivity and soil respiration to understand the influence of the contrasting management practices, using flux variance partitioning. Concomitant with the partitioning, high resolution temporal and spatial scale remote sensing images were interpolated and standardized to conduct hypothesis testing for treatment effects.


Natural, Experimental, And Educational Explorations Of The Interiors Of Terrestrial Planetary Bodies, Nadine L. Grambling Dec 2022

Natural, Experimental, And Educational Explorations Of The Interiors Of Terrestrial Planetary Bodies, Nadine L. Grambling

Doctoral Dissertations

Planetary interiors are enigmatic, inaccessible, and vital to the processes that have formed the rocks we see on the surface of bodies in the inner Solar System today. Based on geophysical explorations of the Moon and Earth, along with information gleaned from rocks at the surface today, there is understanding of the basic structure and processes at depth. Using a combination of natural samples and experimental studies, we attempt to learn more about the physical conditions beneath the surface, and their effect on material properties and tectonics processes in the mantle.

On Earth, mid-ocean ridge processes have long been debated, …


Photo-Reactivity Of Bifunctional Naphthalene Compounds Toward Dna, Qi Zhang Dec 2022

Photo-Reactivity Of Bifunctional Naphthalene Compounds Toward Dna, Qi Zhang

Theses and Dissertations

DNA interstrand cross-link (ICL) can covalently bind two DNA strands, preventing DNA strands separation, and therefore, blocking DNA transcription and replication, which are essential biological processes for cell division. Among different methods to induce DNA interstrand cross-linking, photoinduction is an important way to activate the cross-linking reactions due to its many characteristics, such as non-invasive, controllability, selectivity and biorthogonality. My research mainly focuses on developing novel binaphthalene compounds which can be activated by 350 nm UV light to produce DNA interstrand cross-linking via alkylation. We designed and synthesized a series of binaphthalene analogues with different substituents at the position-4’ on …


Asdot: Any-Shot Data-To-Text Generation With Pretrained Language Models, Jiannan Xiang, Zhengzhong Liu, Yucheng Zhou, Eric P. Xing, Zhiting Hu Dec 2022

Asdot: Any-Shot Data-To-Text Generation With Pretrained Language Models, Jiannan Xiang, Zhengzhong Liu, Yucheng Zhou, Eric P. Xing, Zhiting Hu

Machine Learning Faculty Publications

Data-to-text generation is challenging due to the great variety of the input data in terms of domains (e.g., finance vs sports) or schemata (e.g., diverse predicates). Recent end-to-end neural methods thus require substantial training examples to learn to disambiguate and describe the data. Yet, real-world data-to-text problems often suffer from various data-scarce issues: one may have access to only a handful of or no training examples, and/or have to rely on examples in a different domain or schema. To fill this gap, we propose Any-Shot Data-to-Text (ASDOT), a new approach flexibly applicable to diverse settings by making efficient use of …


Towards The Electronic Response Of Carbon-Based Van Der Waals Heterostructures In A Diamond Anvil Cell, George Thomas Foskaris Dec 2022

Towards The Electronic Response Of Carbon-Based Van Der Waals Heterostructures In A Diamond Anvil Cell, George Thomas Foskaris

UNLV Theses, Dissertations, Professional Papers, and Capstones

The nanoscale regime of materials has been at the forefront of research and interest in condensed matter physics for many years. In a merger of the fields of two-dimensional (2D) materials and high pressure physics, we present an investigation of the electronic response of carbon-based, van der Waals (vdW) heterostructures in a diamond anvil cell (DAC). Combining these fields presents us with the ability to study the characteristics of such systems both optically, and through electrical transport. Properties such as conductance, band structure, and layer number are considered. The samples in this study are assembled using exfoliation and stacking techniques …


South Texas Wildlife Activity Across A Fragmented Landscape And Road Mitigation Corridor, Caitlin K. Brett Dec 2022

South Texas Wildlife Activity Across A Fragmented Landscape And Road Mitigation Corridor, Caitlin K. Brett

Theses and Dissertations

Wildlife crossing structures (WCS) and roadside fencing are commonly installed to mitigate habitat fragmentation, wildlife road mortalities, and other negative effects that roads can have on the surrounding landscape. Eight such WCS were constructed below Farm-to-Market (FM)106 in Cameron County, Texas, across a 16 km corridor transecting the Laguna Atascosa National Wildlife Refuge. These WCS, paired with adjacent roadside fencing, were intended to prevent road mortalities of the endangered ocelot (Leopardus pardalis) and to mitigate the barrier effect of FM106 on this and other meso-mammal species. This study will analyze camera trap data from roadside and habitat reference …


An Assessment Of Physical And Microbial Dynamic Properties Sensitive To Tillage Practices In Hidalgo Sandy Clay Loam Soils, Rocio N. Hernandez Dec 2022

An Assessment Of Physical And Microbial Dynamic Properties Sensitive To Tillage Practices In Hidalgo Sandy Clay Loam Soils, Rocio N. Hernandez

Theses and Dissertations

Mechanized tillage is known to impact the dynamic physical, biological and chemical properties of a given soil, and as a result, can cause systematic harm to the soil’s function (Alam et al., 2014). The aim of this study is to assess how a series of land management tillage practices will impact dynamic physical and biological soil health parameters such as aggregation, carbon, respiration, and enzymatic activity (β-glucosidase). According to Acir et al (2020), the aforementioned soil parameters are both co-influenced and dependent, indicating a response to tillage is likely. A total of 198 samples of Hidalgo series soils were collected …


Glitch Estimation And Removal Using Adaptive Spline Fitting And Wavelet Shrinkage On The Gravitational Wave Data, Mohammad Abu Thaher Chowdhury Dec 2022

Glitch Estimation And Removal Using Adaptive Spline Fitting And Wavelet Shrinkage On The Gravitational Wave Data, Mohammad Abu Thaher Chowdhury

Theses and Dissertations

The false alarm rate and reduced sensitivity of searches for astrophysical signals are caused by transient signals of earthly origin, or "glitches," in gravitational wave strain data from groundbased detectors. The greater number of observable astrophysical signals will increase the likelihood of glitch overlaps and exacerbate their negative impact for future detectors with higher sensitivities. The wide morphological diversity and unpredictable waveforms of glitches, and with the vast majority of cases lacking supplemental data present the main obstacles to their mitigation. Thus, nonparametric glitch mitigation techniques are required, which should operate for a wide range of glitches and, in the …


Investigating The Relationship Between Dissolved Oxygen And Nitrate Concentration As A Proxy For Marine Ecosystem Health, Natalia M. Moore Dec 2022

Investigating The Relationship Between Dissolved Oxygen And Nitrate Concentration As A Proxy For Marine Ecosystem Health, Natalia M. Moore

Theses and Dissertations

Coastal environments such as seagrass meadows span a wide range of spatial scales and can experience disturbances that cause rapid shifts to ecosystem dynamics. Increased pressure to the coastal zone has highlighted the need for constant, real-time monitoring to monitor current ecosystem status. A custom, low cost, high resolution, in situ sensor network was designed and tested in the Lower Laguna Madre, Texas to characterize primary productivity in seagrass meadows through gradient patterns of dissolved oxygen concentration, with the purpose of determining whether seagrass or phytoplankton were the more dominant primary producer. There was a distinct vertical and horizontal gradient …


Dynamic Soil Properties In The Lower Rio Grande Valley: Understanding Responses Of Infiltration Rate, Bulk Density, Aggregate Stability To Different Tillage Practices, Temiloluwa Faith Awotoye Dec 2022

Dynamic Soil Properties In The Lower Rio Grande Valley: Understanding Responses Of Infiltration Rate, Bulk Density, Aggregate Stability To Different Tillage Practices, Temiloluwa Faith Awotoye

Theses and Dissertations

Dynamic Soil Properties (DSPs) are soil properties that change in response to both natural and human-caused interruptions and pressures such as agro-based and wildland management. These soil properties can transform for months or even years in response to the farm use and management procedures. This research project investigates the relationship between different dynamic soil physical properties and tillage practices in the Texas Hidalgo sandy clay loam benchmark soil series. Data analyses was done to compare the effect of tillage to these soil physical properties and build a discussion about relationships between on-farm practices to other aspects of farm viability. We …


Search For Gravitational Waves From Core Collapse Supernovae In Ligo's Observation Runs Using A Network Of Detectors, Shahrear Khan Faisal Dec 2022

Search For Gravitational Waves From Core Collapse Supernovae In Ligo's Observation Runs Using A Network Of Detectors, Shahrear Khan Faisal

Theses and Dissertations

Core-Collapse Supernova (CCSN) is one of the most anticipated sources of Gravitational Waves (GW) in the fourth observation run (O4) of LIGO and other network of GW detectors. A very low rate of galactic CCSN, coupled with the fact that the CCSN waveforms are unmodeled, make detection of these signals extremely challenging. Mukherjee et. al. have developed a new burst search pipeline, the Multi-Layer Signal Enhancement with cWB and CNN or MuLaSEcC, that integrates a non-parametric signal estimation and Machine Learning. MuLaSEcC operates on GW data from a network of detectors and enhances the detection probability while reducing the false …


Dft Investigation Of Lewis Acid Assisted C-Cn Bond Activation Of Benzonitrile With [Ni(Dmpe)] Fragment, Lubna Kader Dec 2022

Dft Investigation Of Lewis Acid Assisted C-Cn Bond Activation Of Benzonitrile With [Ni(Dmpe)] Fragment, Lubna Kader

Theses and Dissertations

There has been recent interest in the field of organometallics with C—C bond activation of organic substrates that are mediated by transition metal complexes. The bond activation of C—C bonds is important, not only in organic synthesis but also in industrial processes. However, the activation of these bonds remains difficult since they are thermodynamically more stable and sterically less available to activate than the activation of the C—H bond. Most of the successful C—C cleavage uses the relief of ring strain, achievement of aromaticity, or proximity, as the driving force for the reaction.3 Another strategy is the use of a …


Gmres Convergence Of Block Preconditioners For Nonsymmetric Matrices, Miguel A. Mascorro Dec 2022

Gmres Convergence Of Block Preconditioners For Nonsymmetric Matrices, Miguel A. Mascorro

Theses and Dissertations

GMRES is an iterative method for solving linear systems that minimizes the residual over the k-dimensional Krylov subspace at iteration k. Murphy, Golub and Wathen in [11] show that saddle point type matrices can be preconditioned so that GMRES converges in two or three steps. Ipsen in [10] extends this work to matrixes where the (2,2) block is nonzero. However, the three step convergence result no longer holds in this case. In this thesis we investigate how many more steps are needed for convergence as a function of the size of that (2,2) block.


Grapefruit Peel Biochar Applications For Immobilizing Copper And Lead In Soil, Michael Alfredo Navarro Dec 2022

Grapefruit Peel Biochar Applications For Immobilizing Copper And Lead In Soil, Michael Alfredo Navarro

Theses and Dissertations

This study investigated the efficacy of grapefruit peel (GP) derived biochar materials (two pyrolysis temperatures 450°C and 800°C) as a potential adsorbent to immobilize heavy metal (copper and lead) in a local sandy loam clay soil. A batch adsorption test with heavy metal concentrations at 50 mg L-1, and 100 mg L-1 revealed that soil itself had the highest immobilization percentage compared to the GP biochars. A soil column experiment was conducted to determine how much the GP biochar samples and the tested soil will exhibit adsorptive characteristics for heavy metals when 50 ml of 50 mg L-1 copper or …


Synthesis Of Bioactive Heterocycles, Shaila Akter Shetu Dec 2022

Synthesis Of Bioactive Heterocycles, Shaila Akter Shetu

Theses and Dissertations

The Discovery of a variety of heterocyclic drugs for the treatment of cancer and other diseases (e.g, neglected tropical diseases) is a medical breakthrough and inspiring for the research community as a whole. A wide range of natural, semi-synthetic, and synthetic anticancer drugs are synthesized using various methods. Among them, β -lactams stand out as a novel class of antibiotics that has different types of biological as well as anti-cancer properties. β -lactam has become a premier and active research subject towards the development of revolutionary anti-cancer drugs. In recent years, a large amount of investigations have been done to …


Spacecraft Charging Test Considerations For Composite Materials, Allen Andersen, Wousik Kim, J. R. Dennison, Brian Wood, Todd A. Schneider, Jason Vaughn, Kenneth H. Wright Jr., Nelson W. Green, Eric Suh, Joel Schwartz, Abdul-Majeed Azad Dec 2022

Spacecraft Charging Test Considerations For Composite Materials, Allen Andersen, Wousik Kim, J. R. Dennison, Brian Wood, Todd A. Schneider, Jason Vaughn, Kenneth H. Wright Jr., Nelson W. Green, Eric Suh, Joel Schwartz, Abdul-Majeed Azad

Journal Articles

Composite materials present a growing challenge for spacecraft charging assessments. We review some recent lessons learned for charging tests of composite materials using both parallel-plate and electron beam test geometries. We also discuss examples of materials that exhibit significant variations between samples, despite them all having the same trade name.


Rapid Detection Of Recurrent Non-Muscle Invasive Bladder Cancer In Urine Using Atr-Ftir Technology, Abdullah I. El-Falouji, Dalia M. Sabri, Naira M. Lofti, Doaa M. Medany, Samar A. Mohamed, Mai Alaa-Eldin, Amr Mounir Selim, Asmaa A. El Leithy, Haitham F. Kalil, Ahmed El-Tobgy, Ahmed Mohamed Dec 2022

Rapid Detection Of Recurrent Non-Muscle Invasive Bladder Cancer In Urine Using Atr-Ftir Technology, Abdullah I. El-Falouji, Dalia M. Sabri, Naira M. Lofti, Doaa M. Medany, Samar A. Mohamed, Mai Alaa-Eldin, Amr Mounir Selim, Asmaa A. El Leithy, Haitham F. Kalil, Ahmed El-Tobgy, Ahmed Mohamed

Chemistry Faculty Publications

Non-muscle Invasive Bladder Cancer (NMIBC) accounts for 80% of all bladder cancers. Although it is mostly low-grade tumors, its high recurrence rate necessitates three-times-monthly follow-ups and cystoscopy examinations to detect and prevent its progression. A rapid liquid biopsy-based assay is needed to improve detection and reduce complications from invasive cystoscopy. Here, we present a rapid spectroscopic method to detect the recurrence of NMIBC in urine. Urine samples from previously-diagnosed NMIBC patients (n = 62) were collected during their follow-up visits before cystoscopy examination. Cystoscopy results were recorded (41 cancer-free and 21 recurrence) and attenuated total refraction Fourier transform infrared (ATR-FTIR) …